Search of human proteins with 116686106

Search of human proteins with 116686106

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116686106 diptheria toxin resistance protein required for
diphthamide biosynthesis-like 1 [Homo sapiens]
         (443 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116686106 diptheria toxin resistance protein required for dip...   892   0.0  
gi|21536476 diphthamide biosynthesis protein 2 isoform a [Homo s...   101   1e-21
gi|88853059 diphthamide biosynthesis protein 2 isoform b [Homo s...    64   4e-10
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin...    30   3.4  
gi|115387102 adenylate cyclase 2 [Homo sapiens]                        30   4.4  
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ...    29   9.8  

>gi|116686106 diptheria toxin resistance protein required for
           diphthamide biosynthesis-like 1 [Homo sapiens]
          Length = 443

 Score =  892 bits (2305), Expect = 0.0
 Identities = 443/443 (100%), Positives = 443/443 (100%)

Query: 1   MRRQVMAALVVSGAAEQGGRDGPGRGRAPRGRVANQIPPEILKNPQLQAAIRVLPSNYNF 60
           MRRQVMAALVVSGAAEQGGRDGPGRGRAPRGRVANQIPPEILKNPQLQAAIRVLPSNYNF
Sbjct: 1   MRRQVMAALVVSGAAEQGGRDGPGRGRAPRGRVANQIPPEILKNPQLQAAIRVLPSNYNF 60

Query: 61  EIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDF 120
           EIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDF
Sbjct: 61  EIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDDF 120

Query: 121 TARALGADFLVHYGHSCLIPMDTSAQDFRVLYVFVDIRIDTTHLLDSLRLTFPPATALAL 180
           TARALGADFLVHYGHSCLIPMDTSAQDFRVLYVFVDIRIDTTHLLDSLRLTFPPATALAL
Sbjct: 121 TARALGADFLVHYGHSCLIPMDTSAQDFRVLYVFVDIRIDTTHLLDSLRLTFPPATALAL 180

Query: 181 VSTIQFVSTLQAAAQELKAEYRVSVPQCKPLSPGEILGCTSPRLSKEVEAVVYLGDGRFH 240
           VSTIQFVSTLQAAAQELKAEYRVSVPQCKPLSPGEILGCTSPRLSKEVEAVVYLGDGRFH
Sbjct: 181 VSTIQFVSTLQAAAQELKAEYRVSVPQCKPLSPGEILGCTSPRLSKEVEAVVYLGDGRFH 240

Query: 241 LESVMIANPNVPAYRYDPYSKVLSREHYDHQRMQAARQEAIATARSAKSWGLILGTLGRQ 300
           LESVMIANPNVPAYRYDPYSKVLSREHYDHQRMQAARQEAIATARSAKSWGLILGTLGRQ
Sbjct: 241 LESVMIANPNVPAYRYDPYSKVLSREHYDHQRMQAARQEAIATARSAKSWGLILGTLGRQ 300

Query: 301 GSPKILEHLESRLRALGLSFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGTAFPK 360
           GSPKILEHLESRLRALGLSFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGTAFPK
Sbjct: 301 GSPKILEHLESRLRALGLSFVRLLLSEIFPSKLSLLPEVDVWVQVACPRLSIDWGTAFPK 360

Query: 361 PLLTPYEAAVALRDISWQQPYPMDFYAGSSLGPWTVNHGQDRRPHAPGRPARGKVQEGSA 420
           PLLTPYEAAVALRDISWQQPYPMDFYAGSSLGPWTVNHGQDRRPHAPGRPARGKVQEGSA
Sbjct: 361 PLLTPYEAAVALRDISWQQPYPMDFYAGSSLGPWTVNHGQDRRPHAPGRPARGKVQEGSA 420

Query: 421 RPPSAVACEDCSCRDEKVAPLAP 443
           RPPSAVACEDCSCRDEKVAPLAP
Sbjct: 421 RPPSAVACEDCSCRDEKVAPLAP 443


>gi|21536476 diphthamide biosynthesis protein 2 isoform a [Homo
           sapiens]
          Length = 489

 Score =  101 bits (252), Expect = 1e-21
 Identities = 97/356 (27%), Positives = 149/356 (41%), Gaps = 48/356 (13%)

Query: 60  FEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDD 119
           +E+ +    ++    ++VALQ P+ LL  A  +   LE  T +++ ++GD  YG+CCVD 
Sbjct: 33  YELERVAGFVRDLGCERVALQFPDQLLGDAVAVAARLEETTGSKMFILGDTAYGSCCVDV 92

Query: 120 FTARALGADFLVHYGHSCLIPMDTSAQDFRVLYVFVDIRIDTTHLLDSLRLTFP-PATAL 178
             A   GA  L+H+G +CL P    A+   V +V     +     + +     P P   +
Sbjct: 93  LGAEQAGAQALIHFGPACLSP---PARPLPVAFVLRQRSVALELCVKAFEAQNPDPKAPV 149

Query: 179 ALVSTIQFVSTLQAAAQELKAEY---RVSVPQCK--------------------PLSPGE 215
            L+S       L+A A  L+  Y    VS P                       PL+PG 
Sbjct: 150 VLLSEPACAHALEALATLLRPRYLDLLVSSPAFPQPVGSLSPEPMPLERFGRRFPLAPGR 209

Query: 216 ILGCTSPRLSKEVEAVVYLGDGRF--------HLESVMIA-NPNVPAYRYDPYSKVLSRE 266
            L         E     Y+G  +          L  +++   P  P     P +     E
Sbjct: 210 RL---------EEYGAFYVGGSKASPDPDLDPDLSRLLLGWAPGQPFSSCCPDTGKTQDE 260

Query: 267 HYDHQRMQAARQEAIATARSAKSWGLILGTLGRQGSPKILEHLESRLRALGLSFVRLLLS 326
                R++A R+  +  AR A+  GL+ GTLG     + L HL +  +A G     L L 
Sbjct: 261 GARAGRLRARRRYLVERARDARVVGLLAGTLGVAQHREALAHLRNLTQAAGKRSYVLALG 320

Query: 327 EIFPSKLSLLPEVDVWVQVACP--RLSIDWGTAFPKPLLTPYEAAVALRDISWQQP 380
              P+KL+  PEVDV+V +ACP   L+     +F +P+L P E   A    +W  P
Sbjct: 321 RPTPAKLANFPEVDVFVLLACPLGALAPQLSGSFFQPILAPCELEAACNP-AWPPP 375


>gi|88853059 diphthamide biosynthesis protein 2 isoform b [Homo
           sapiens]
          Length = 261

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 29/81 (35%), Positives = 47/81 (58%)

Query: 60  FEIPKTIWRIQQAQAKKVALQMPEGLLLFACTIVDILERFTEAEVMVMGDVTYGACCVDD 119
           +E+ +    ++    ++VALQ P+ LL  A  +   LE  T +++ ++GD  YG+CCVD 
Sbjct: 33  YELERVAGFVRDLGCERVALQFPDQLLGDAVAVAARLEETTGSKMFILGDTAYGSCCVDV 92

Query: 120 FTARALGADFLVHYGHSCLIP 140
             A   GA  L+H+G +CL P
Sbjct: 93  LGAEQAGAQALIHFGPACLSP 113


>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
           isoform a [Homo sapiens]
          Length = 1749

 Score = 30.4 bits (67), Expect = 3.4
 Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 11/93 (11%)

Query: 355 GTAFPKPLLTPYEAAVALRDISWQQPYPMDFYAGS----SLGPWTVNHGQDRRPHAPGRP 410
           G+  P P   P +A+    +    +P P    +G     +LGP T +HG    P  P +P
Sbjct: 779 GSPVPAP---PTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHG----PRHPPKP 831

Query: 411 ARGKVQEGSARPPSAVACEDCSCRDEKVAPLAP 443
            R K  E   + P          RD++     P
Sbjct: 832 PRSKATERPGQEPEGPGATPAGERDDQSPDSVP 864


>gi|115387102 adenylate cyclase 2 [Homo sapiens]
          Length = 1091

 Score = 30.0 bits (66), Expect = 4.4
 Identities = 18/76 (23%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 118 DDFTARALGADFLVHYGHSCLIPMDTSAQDFRVLYVFVDIR---IDTTHLLDSLRLTFPP 174
           + F AR+L  + L H  + C+  M  S  DF+  Y   D+    ++   LL+ +   F  
Sbjct: 866 EHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDD 925

Query: 175 ATALALVSTIQFVSTL 190
             +    S ++ + T+
Sbjct: 926 LLSKPKFSGVEKIKTI 941


>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1
           [Homo sapiens]
          Length = 1194

 Score = 28.9 bits (63), Expect = 9.8
 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 12/100 (12%)

Query: 206 PQCKPLSPGEILGCTSPRLSKE-------VEAVVYLGDGRFHLESVMI-ANPNVPAYR-- 255
           P C   +PG  +   S  L KE       + +V+    G  H +  ++  + N P  +  
Sbjct: 28  PMCVNPTPGGTISRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKV 87

Query: 256 --YDPYSKVLSREHYDHQRMQAARQEAIATARSAKSWGLI 293
             +  + K +  E Y  +++ A RQ A A  +  K WGL+
Sbjct: 88  TLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLL 127


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,810,351
Number of Sequences: 37866
Number of extensions: 824539
Number of successful extensions: 2496
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2491
Number of HSP's gapped (non-prelim): 7
length of query: 443
length of database: 18,247,518
effective HSP length: 105
effective length of query: 338
effective length of database: 14,271,588
effective search space: 4823796744
effective search space used: 4823796744
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.