Search of human proteins with 229577352

Search of human proteins with 229577352

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|229577352 coiled-coil and C2 domain containing 2B isoform 1
[Homo sapiens]
         (401 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|229577352 coiled-coil and C2 domain containing 2B isoform 1 [...   835   0.0  
gi|109452583 coiled-coil and C2 domain containing 2B isoform 2 [...   544   e-155
gi|197209817 coiled-coil and C2 domain containing 2A isoform b [...   397   e-111
gi|197209974 coiled-coil and C2 domain containing 2A isoform a [...   376   e-104
gi|21314728 centrosomal protein 76kDa [Homo sapiens]                   78   1e-14
gi|4507525 translocation protein 1 [Homo sapiens]                      29   6.6  

>gi|229577352 coiled-coil and C2 domain containing 2B isoform 1
           [Homo sapiens]
          Length = 401

 Score =  835 bits (2157), Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%)

Query: 1   MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA 60
           MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA
Sbjct: 1   MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA 60

Query: 61  MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP 120
           MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP
Sbjct: 61  MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP 120

Query: 121 NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180
           NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV
Sbjct: 121 NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180

Query: 181 VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE 240
           VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE
Sbjct: 181 VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE 240

Query: 241 SFWKQLLPKNVQGTKIQSIQPEEIIYFETDKSMVEDLRNRIERTLKSKVMEWRPKHPTHW 300
           SFWKQLLPKNVQGTKIQSIQPEEIIYFETDKSMVEDLRNRIERTLKSKVMEWRPKHPTHW
Sbjct: 241 SFWKQLLPKNVQGTKIQSIQPEEIIYFETDKSMVEDLRNRIERTLKSKVMEWRPKHPTHW 300

Query: 301 NRQCTFILRQILPKLEFGIGSFVSSEGDNEFERILQFYWVTGFPIQMPYIDVQSIIDAVY 360
           NRQCTFILRQILPKLEFGIGSFVSSEGDNEFERILQFYWVTGFPIQMPYIDVQSIIDAVY
Sbjct: 301 NRQCTFILRQILPKLEFGIGSFVSSEGDNEFERILQFYWVTGFPIQMPYIDVQSIIDAVY 360

Query: 361 QTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQHQ 401
           QTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQHQ
Sbjct: 361 QTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQHQ 401


>gi|109452583 coiled-coil and C2 domain containing 2B isoform 2
           [Homo sapiens]
          Length = 322

 Score =  544 bits (1401), Expect = e-155
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA 60
           MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA
Sbjct: 1   MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA 60

Query: 61  MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP 120
           MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP
Sbjct: 61  MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP 120

Query: 121 NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180
           NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV
Sbjct: 121 NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180

Query: 181 VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE 240
           VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE
Sbjct: 181 VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE 240

Query: 241 SFWKQLLPKNVQGTKIQSIQ 260
           SFWKQLLPKNVQGTKIQSIQ
Sbjct: 241 SFWKQLLPKNVQGTKIQSIQ 260



 Score =  131 bits (329), Expect = 1e-30
 Identities = 63/67 (94%), Positives = 64/67 (95%)

Query: 335 LQFYWVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYL 394
           +Q   VTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYL
Sbjct: 256 IQSIQVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYL 315

Query: 395 ASLVQHQ 401
           ASLVQHQ
Sbjct: 316 ASLVQHQ 322


>gi|197209817 coiled-coil and C2 domain containing 2A isoform b [Homo
            sapiens]
          Length = 1512

 Score =  397 bits (1020), Expect = e-111
 Identities = 184/397 (46%), Positives = 264/397 (66%), Gaps = 2/397 (0%)

Query: 7    EDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTE--VLQRAQIFKKNCKAMFPN 64
            ED   +    H+ I ++WLGC+  PFS +  Q+ F  Q +  +LQ  + F+  C   FPN
Sbjct: 1116 EDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARFESQEDEKLLQATEKFQAECALKFPN 1175

Query: 65   RRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNTPD 124
            R+ +TTV +  G    +TRY+K LNPPQ+LL+++ +N  AT +L+AR+VSLIPF+P+T  
Sbjct: 1176 RQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVS 1235

Query: 125  ENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYVVTQE 184
                 D+W TS+  + L  G++EEHA+LLCN+FL  GKKA +L+G ++ EG  AYV+T E
Sbjct: 1236 FGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWE 1295

Query: 185  TNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKESFWK 244
               YL+WNP +G  Y QFD FCPLK+V CL    N+WFNIQ+  +P+ + FD ++   WK
Sbjct: 1296 QGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWK 1355

Query: 245  QLLPKNVQGTKIQSIQPEEIIYFETDKSMVEDLRNRIERTLKSKVMEWRPKHPTHWNRQC 304
                +++    + S+QPEE+IY  +DK+   +L++RIE+ LK K+M+WRP+H T WNR C
Sbjct: 1356 SFFSRSLPYPGLSSVQPEELIYQRSDKAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYC 1415

Query: 305  TFILRQILPKLEFGIGSFVSSEGDNEFERILQFYWVTGFPIQMPYIDVQSIIDAVYQTGI 364
            T  LR  LP LE   G  V  +   E  + L  Y  +GFP+ MPY +V+ +IDAVY TG+
Sbjct: 1416 TSTLRHFLPLLEKSQGEDVEDDHRAELLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGV 1475

Query: 365  HSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQHQ 401
            H+ + P  EFALAVYIHPYP N+LSVW+Y+ASL++++
Sbjct: 1476 HNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRNR 1512


>gi|197209974 coiled-coil and C2 domain containing 2A isoform a [Homo
            sapiens]
          Length = 1620

 Score =  376 bits (966), Expect = e-104
 Identities = 172/371 (46%), Positives = 250/371 (67%)

Query: 31   PFSALLQQSEFLDQTEVLQRAQIFKKNCKAMFPNRRIVTTVFNDEGIQFLVTRYIKALNP 90
            P  ++ ++ E  +  ++LQ  + F+  C   FPNR+ +TTV +  G    +TRY+K LNP
Sbjct: 1250 PGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNP 1309

Query: 91   PQQLLDIFLHNSNATFDLIARFVSLIPFVPNTPDENDGSDIWMTSEHCISLAIGNKEEHA 150
            PQ+LL+++ +N  AT +L+AR+VSLIPF+P+T       D+W TS+  + L  G++EEHA
Sbjct: 1310 PQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHA 1369

Query: 151  ILLCNFFLYFGKKALVLLGTSVLEGHVAYVVTQETNEYLLWNPSTGQCYKQFDPFCPLKS 210
            +LLCN+FL  GKKA +L+G ++ EG  AYV+T E   YL+WNP +G  Y QFD FCPLK+
Sbjct: 1370 VLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKN 1429

Query: 211  VDCLFDDRNVWFNIQQNNTPMAVFFDYSKESFWKQLLPKNVQGTKIQSIQPEEIIYFETD 270
            V CL    N+WFNIQ+  +P+ + FD ++   WK    +++    + S+QPEE+IY  +D
Sbjct: 1430 VGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQPEELIYQRSD 1489

Query: 271  KSMVEDLRNRIERTLKSKVMEWRPKHPTHWNRQCTFILRQILPKLEFGIGSFVSSEGDNE 330
            K+   +L++RIE+ LK K+M+WRP+H T WNR CT  LR  LP LE   G  V  +   E
Sbjct: 1490 KAAAAELQDRIEKILKEKIMDWRPRHLTRWNRYCTSTLRHFLPLLEKSQGEDVEDDHRAE 1549

Query: 331  FERILQFYWVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSV 390
              + L  Y  +GFP+ MPY +V+ +IDAVY TG+H+ + P  EFALAVYIHPYP N+LSV
Sbjct: 1550 LLKQLGDYRFSGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSV 1609

Query: 391  WVYLASLVQHQ 401
            W+Y+ASL++++
Sbjct: 1610 WIYVASLIRNR 1620



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 12/33 (36%), Positives = 19/33 (57%)

Query: 7    EDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQS 39
            ED   +    H+ I ++WLGC+  PFS +  Q+
Sbjct: 1165 EDDRERGSGIHTRIERHWLGCVKMPFSTIYFQA 1197


>gi|21314728 centrosomal protein 76kDa [Homo sapiens]
          Length = 659

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 93/364 (25%), Positives = 152/364 (41%), Gaps = 45/364 (12%)

Query: 64  NRRIVTTVFNDE-GIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNT 122
           N R+V     DE GI   V  Y+K L   + LLD        T    ARFV+++ +    
Sbjct: 302 NSRLVKIFAQDENGINRPVCSYVKPLRAGR-LLD--------TPRQAARFVNVLGY-ERA 351

Query: 123 PDENDGS--DIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180
           P    G   + W T    +    G+ E+HA LLC+  L +G +A V +GT       A+V
Sbjct: 352 PVIGGGGKQEQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWV 411

Query: 181 VTQETNEYL-LWNPSTGQCY-------------KQFDPFCPLKSVDCLFDDRNVWFNIQQ 226
           +T  T+  +  W   TG  Y             +Q  P  P +++ C+F+ +    N Q 
Sbjct: 412 MTCGTDGAITFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQP 471

Query: 227 NNTPMAVFFDYSKESFWKQLLPKNVQGT----KIQSIQPEEIIYFETDKSMVEDLRNRIE 282
           ++      FD + ES WK +  + ++         S+ P   +   T  + V    N IE
Sbjct: 472 SDAVETCVFDLNDESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTS--NEIE 529

Query: 283 RTLKSKVMEWRPK--HPTHWNRQCTFILRQILPKLEFGIGSFVSSEGDNEFERILQ---- 336
             L+  V E R      T W  Q +++L   L   EF   + +S+ G+ EF+  ++    
Sbjct: 530 MQLRLLVSEHRKDLGLTTVWEDQLSYLLSPALASYEFERTTSISA-GNEEFQDAIRRAVP 588

Query: 337 -FYWVTGFPIQMPYIDVQ----SIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVW 391
             +   GFPI   Y + +    + + + +   I      Q   A+ V +  YP +  +VW
Sbjct: 589 DGHTFKGFPIHFVYRNARRAFATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVW 648

Query: 392 VYLA 395
           +  A
Sbjct: 649 IMFA 652


>gi|4507525 translocation protein 1 [Homo sapiens]
          Length = 399

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 12/116 (10%)

Query: 187 EYLLWN---PSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNN----TPMAVFFDYSK 239
           +YL +N    ST     + D F   K+VDCL D +  W   ++      T      DY  
Sbjct: 26  KYLRFNCPTKSTNMMGHRVDYFIASKAVDCLLDSK--WAKAKKGEEALFTTRESVVDYCN 83

Query: 240 ESFWKQLLPKNVQGTKIQSIQPEEIIYFETDKSMVEDLRNRIERTLKSKVMEWRPK 295
               KQ   +     K+  ++ ++ I  E DK   E  +   +++ K  + + + K
Sbjct: 84  RLLKKQFFHR---ALKVMKMKYDKDIKKEKDKGKAESGKEEDKKSKKENIKDEKTK 136


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,096,345
Number of Sequences: 37866
Number of extensions: 635154
Number of successful extensions: 1528
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1518
Number of HSP's gapped (non-prelim): 8
length of query: 401
length of database: 18,247,518
effective HSP length: 104
effective length of query: 297
effective length of database: 14,309,454
effective search space: 4249907838
effective search space used: 4249907838
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.