Search of human proteins with 22749023

Search of human proteins with 22749023

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22749023 transmembrane protein 56 [Homo sapiens]
         (263 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22749023 transmembrane protein 56 [Homo sapiens]                   531   e-151
gi|31083053 ceroid-lipofuscinosis, neuronal 8 [Homo sapiens]           44   2e-04
gi|19923999 TLC domain containing 1 isoform 1 [Homo sapiens]           43   2e-04
gi|239756685 PREDICTED: TLC domain containing 2 [Homo sapiens]         39   0.004
gi|239751182 PREDICTED: hypothetical protein [Homo sapiens]            39   0.004
gi|239745670 PREDICTED: TLC domain containing 2 [Homo sapiens]         39   0.004
gi|237874289 TLC domain containing 1 isoform 2 [Homo sapiens]          34   0.11 
gi|122937404 membrane bound O-acyltransferase domain containing ...    28   8.2  

>gi|22749023 transmembrane protein 56 [Homo sapiens]
          Length = 263

 Score =  531 bits (1368), Expect = e-151
 Identities = 263/263 (100%), Positives = 263/263 (100%)

Query: 1   MEINTKLLISVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSL 60
           MEINTKLLISVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSL
Sbjct: 1   MEINTKLLISVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSL 60

Query: 61  VVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIGDKFFIM 120
           VVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIGDKFFIM
Sbjct: 61  VVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIGDKFFIM 120

Query: 121 HHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALKYPKFSKAIVINGILM 180
           HHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALKYPKFSKAIVINGILM
Sbjct: 121 HHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALKYPKFSKAIVINGILM 180

Query: 181 TVVFFIVRIASMLPHYGFMYSVYGTEPYIRLGVLIQLSWVISCVVLDVMNVMWMIKISKG 240
           TVVFFIVRIASMLPHYGFMYSVYGTEPYIRLGVLIQLSWVISCVVLDVMNVMWMIKISKG
Sbjct: 181 TVVFFIVRIASMLPHYGFMYSVYGTEPYIRLGVLIQLSWVISCVVLDVMNVMWMIKISKG 240

Query: 241 CIKVISHIRQEKAKNSLQNGKLD 263
           CIKVISHIRQEKAKNSLQNGKLD
Sbjct: 241 CIKVISHIRQEKAKNSLQNGKLD 263


>gi|31083053 ceroid-lipofuscinosis, neuronal 8 [Homo sapiens]
          Length = 286

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 3/153 (1%)

Query: 10  SVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSLVVGIFGLYI 69
           S   ++ F F L  + V +  S+ ++  + SL  ++K+ W+         +     GL+ 
Sbjct: 25  STLMVAGFVFYLGVFVVCHQLSSSLNATYRSLVAREKVFWDLAATRAVFGVQSTAAGLWA 84

Query: 70  FLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIG--DKFFIMHHCASLY 127
            L D    AD   G  +    +I  A+G+   +   + L   +    D F ++HH  +  
Sbjct: 85  LLGDPVLHADKARGQQNWCWFHITTATGFFCFENVAVHLSNLIFRTFDLFLVIHHLFAFL 144

Query: 128 AYYLVLKNGVLA-YIGNFRLLAELSSPFVNQRW 159
            +   L N     Y+    LL E+S+PF    W
Sbjct: 145 GFLGCLVNLQAGHYLAMTTLLLEMSTPFTCVSW 177


>gi|19923999 TLC domain containing 1 isoform 1 [Homo sapiens]
          Length = 247

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 42/178 (23%), Positives = 81/178 (45%), Gaps = 9/178 (5%)

Query: 49  WNSRVVSTCHSLVVGIFGLYIF--LFDEATKADPLWGGPSLAN-VNIAIASGYLISDLSI 105
           W++ +VS  HS+V GI+ L       D   + +  W   SL+  + +  ++GY I D   
Sbjct: 45  WHNLLVSFAHSIVSGIWALLCVWQTPDMLVEIETAW---SLSGYLLVCFSAGYFIHDTVD 101

Query: 106 IILYWKVIGDKFFIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALK 165
           I+   +      +++HH  ++ A++  +        G   LL E+S+ F+  R   + + 
Sbjct: 102 IVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVSNIFLTIRMMMK-IS 160

Query: 166 YPKFSKAIVINGILMTVVFFIVRIA--SMLPHYGFMYSVYGTEPYIRLGVLIQLSWVI 221
             +      +N  +  V++F+ R+A  + L H+   Y    T     LG+L+ L  +I
Sbjct: 161 NAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTFLLGILLMLDVMI 218


>gi|239756685 PREDICTED: TLC domain containing 2 [Homo sapiens]
          Length = 264

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 2/112 (1%)

Query: 48  EWNSRVVSTCHSLVVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIII 107
           +W +  VS  HSL+ G   L          ADP+ G P  A V +A++ GY ++D    +
Sbjct: 38  QWWNLCVSLAHSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLAD-GADL 96

Query: 108 LYWKVIGDKF-FIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQR 158
           L+ + +G  +  + HH   +      + +G         LL EL+S  ++ R
Sbjct: 97  LWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLR 148


>gi|239751182 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 264

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 2/112 (1%)

Query: 48  EWNSRVVSTCHSLVVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIII 107
           +W +  VS  HSL+ G   L          ADP+ G P  A V +A++ GY ++D    +
Sbjct: 38  QWWNLCVSLAHSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLAD-GADL 96

Query: 108 LYWKVIGDKF-FIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQR 158
           L+ + +G  +  + HH   +      + +G         LL EL+S  ++ R
Sbjct: 97  LWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLR 148


>gi|239745670 PREDICTED: TLC domain containing 2 [Homo sapiens]
          Length = 264

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 2/112 (1%)

Query: 48  EWNSRVVSTCHSLVVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIII 107
           +W +  VS  HSL+ G   L          ADP+ G P  A V +A++ GY ++D    +
Sbjct: 38  QWWNLCVSLAHSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLAD-GADL 96

Query: 108 LYWKVIGDKF-FIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQR 158
           L+ + +G  +  + HH   +      + +G         LL EL+S  ++ R
Sbjct: 97  LWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLR 148


>gi|237874289 TLC domain containing 1 isoform 2 [Homo sapiens]
          Length = 200

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 29/132 (21%), Positives = 59/132 (44%), Gaps = 3/132 (2%)

Query: 92  IAIASGYLISDLSIIILYWKVIGDKFFIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELS 151
           +  ++GY I D   I+   +      +++HH  ++ A++  +        G   LL E+S
Sbjct: 41  VCFSAGYFIHDTVDIVASGQTRASWEYLVHHVMAMGAFFSGIFWSSFVGGGVLTLLVEVS 100

Query: 152 SPFVNQRWFFEALKYPKFSKAIVINGILMTVVFFIVRIA--SMLPHYGFMYSVYGTEPYI 209
           + F+  R   + +   +      +N  +  V++F+ R+A  + L H+   Y    T    
Sbjct: 101 NIFLTIRMMMK-ISNAQDHLLYRVNKYVNLVMYFLFRLAPQAYLTHFFLRYVNQRTLGTF 159

Query: 210 RLGVLIQLSWVI 221
            LG+L+ L  +I
Sbjct: 160 LLGILLMLDVMI 171


>gi|122937404 membrane bound O-acyltransferase domain containing 1
          [Homo sapiens]
          Length = 495

 Score = 28.1 bits (61), Expect = 8.2
 Identities = 16/59 (27%), Positives = 24/59 (40%), Gaps = 14/59 (23%)

Query: 14 ISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSLVVGIFGLYIFLF 72
          ++F   QL+  F ++WF   + PG  S              S     V  IFG+Y  +F
Sbjct: 34 VNFVVCQLVALFAAFWFRIYLRPGTTS--------------SDVRHAVATIFGIYFVIF 78


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.142    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,695,316
Number of Sequences: 37866
Number of extensions: 326668
Number of successful extensions: 793
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 785
Number of HSP's gapped (non-prelim): 9
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.