Guide to the Human Genome
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Search of human proteins with 226529429

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226529429 Na+/K+ transporting ATPase interacting 4 [Homo
sapiens]
         (208 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226529429 Na+/K+ transporting ATPase interacting 4 [Homo sapi...   434   e-122
gi|94158939 T-cell lymphoma breakpoint-associated target 1 [Homo...   254   4e-68
gi|27735000 Na+/K+ transporting ATPase interacting 3 [Homo sapiens]   253   1e-67
gi|13375664 Na+/K+ transporting ATPase interacting 1 [Homo sapiens]   164   4e-41
gi|58530842 desmoplakin isoform II [Homo sapiens]                      29   3.2  
gi|58530840 desmoplakin isoform I [Homo sapiens]                       29   3.2  
gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo s...    29   3.2  
gi|16306483 solute carrier family 26, member 7 isoform a [Homo s...    29   3.2  
gi|20336282 solute carrier family 26, member 7 isoform b [Homo s...    29   3.2  
gi|94538366 transient receptor potential cation channel, subfami...    27   9.4  

>gi|226529429 Na+/K+ transporting ATPase interacting 4 [Homo
           sapiens]
          Length = 208

 Score =  434 bits (1117), Expect = e-122
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MGSCSGRCALVVLCAFQLVAALERQVFDFLGYQWAPILANFVHIIIVILGLFGTIQYRLR 60
           MGSCSGRCALVVLCAFQLVAALERQVFDFLGYQWAPILANFVHIIIVILGLFGTIQYRLR
Sbjct: 1   MGSCSGRCALVVLCAFQLVAALERQVFDFLGYQWAPILANFVHIIIVILGLFGTIQYRLR 60

Query: 61  YVMVYTLWAAVWVTWNVFIICFYLEVGGLLKDSELLTFSLSRHRSWWRERWPGCLHEEVP 120
           YVMVYTLWAAVWVTWNVFIICFYLEVGGLLKDSELLTFSLSRHRSWWRERWPGCLHEEVP
Sbjct: 61  YVMVYTLWAAVWVTWNVFIICFYLEVGGLLKDSELLTFSLSRHRSWWRERWPGCLHEEVP 120

Query: 121 AVGLGAPHGQALVSGAGCALEPSYVEALHSCLQILIALLGFVCGCQVVSVFTEEEDSFDF 180
           AVGLGAPHGQALVSGAGCALEPSYVEALHSCLQILIALLGFVCGCQVVSVFTEEEDSFDF
Sbjct: 121 AVGLGAPHGQALVSGAGCALEPSYVEALHSCLQILIALLGFVCGCQVVSVFTEEEDSFDF 180

Query: 181 IGGFDPFPLYHVNEKPSSLLSKQVYLPA 208
           IGGFDPFPLYHVNEKPSSLLSKQVYLPA
Sbjct: 181 IGGFDPFPLYHVNEKPSSLLSKQVYLPA 208


>gi|94158939 T-cell lymphoma breakpoint-associated target 1 [Homo
           sapiens]
          Length = 208

 Score =  254 bits (649), Expect = 4e-68
 Identities = 122/207 (58%), Positives = 146/207 (70%), Gaps = 2/207 (0%)

Query: 1   MGSCSGRCALVVLCAFQLVAALERQVFDFLGYQWAPILANFVHIIIVILGLFGTIQYRLR 60
           MG CSGRC L+ +C  QLV  LERQ+FDFLGYQWAPILANFVHIIIVILGLFGTIQYR R
Sbjct: 1   MGYCSGRCTLIFICGMQLVCVLERQIFDFLGYQWAPILANFVHIIIVILGLFGTIQYRPR 60

Query: 61  YVMVYTLWAAVWVTWNVFIICFYLEVGGLLKDSEL-LTFSLSRHRSWWRERWPGCLHEEV 119
           Y+  Y +W  +WVTWNVF+ICFYLE G L K+++L LTF++S HRSWW E  PGC    V
Sbjct: 61  YITGYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSV 120

Query: 120 PAVGLGAPHGQALVSGAGCALEPSYVEALHSCLQILIALLGFVCGCQVVSVFTEEEDSFD 179
                 AP     ++ +GC LE  Y+E  HS LQI++AL GF+  C VV   TEEEDSFD
Sbjct: 121 TPAPDWAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCITEEEDSFD 180

Query: 180 FIGGFDPFPLYHVNEKPSSLLSKQVYL 206
           FIGGFD +  Y   +K S L  + +Y+
Sbjct: 181 FIGGFDSYG-YQGPQKTSHLQLQPMYM 206


>gi|27735000 Na+/K+ transporting ATPase interacting 3 [Homo sapiens]
          Length = 197

 Score =  253 bits (645), Expect = 1e-67
 Identities = 112/178 (62%), Positives = 142/178 (79%)

Query: 1   MGSCSGRCALVVLCAFQLVAALERQVFDFLGYQWAPILANFVHIIIVILGLFGTIQYRLR 60
           MG C+GRC+L+ LCA QLV+ALERQ+FDFLG+QWAPIL NF+HII+VILGLFGTIQYR R
Sbjct: 1   MGCCTGRCSLICLCALQLVSALERQIFDFLGFQWAPILGNFLHIIVVILGLFGTIQYRPR 60

Query: 61  YVMVYTLWAAVWVTWNVFIICFYLEVGGLLKDSELLTFSLSRHRSWWRERWPGCLHEEVP 120
           Y+MVYT+W A+WVTWNVFIICFYLEVGGL KD++L+TF++S HRSWWRE  PGC+   +P
Sbjct: 61  YIMVYTVWTALWVTWNVFIICFYLEVGGLSKDTDLMTFNISVHRSWWREHGPGCVRRVLP 120

Query: 121 AVGLGAPHGQALVSGAGCALEPSYVEALHSCLQILIALLGFVCGCQVVSVFTEEEDSF 178
               G       VS  GC ++  Y+E +HS +QIL++L+GFV  C V+S+  EEED++
Sbjct: 121 PSAHGMMDDYTYVSVTGCIVDFQYLEVIHSAVQILLSLVGFVYACYVISISMEEEDTY 178


>gi|13375664 Na+/K+ transporting ATPase interacting 1 [Homo sapiens]
          Length = 163

 Score =  164 bits (416), Expect = 4e-41
 Identities = 85/160 (53%), Positives = 105/160 (65%), Gaps = 3/160 (1%)

Query: 47  VILGLFGTIQYRLRYVMVYTLWAAVWVTWNVFIICFYLEVGGLLKDSE-LLTFSLSRHRS 105
           VILG+FGT+QYR RY+++Y  W  +WV WN FIICFYLEVG L +D + ++TF+ S HRS
Sbjct: 3   VILGIFGTVQYRSRYLILYAAWLVLWVGWNAFIICFYLEVGQLSQDRDFIMTFNTSLHRS 62

Query: 106 WWRERWPGCLHEEVPAVGLGAPHGQALVSGAGCALEPSYVEALHSCLQILIALLGFVCGC 165
           WW E  PGCL   V    L A     ++S  GC L+  Y+EAL S LQI +AL GFV  C
Sbjct: 63  WWMENGPGCLVTPVLNSRL-ALEDHHVISVTGCLLDYPYIEALSSALQIFLALFGFVFAC 121

Query: 166 QVVSVFTEEEDSFDFIGGFDPFPLYHVNEKPSSLLSKQVY 205
            V  VF EEEDSFDFIGGFD +  Y   +K S L  + +Y
Sbjct: 122 YVSKVFLEEEDSFDFIGGFDSYG-YQAPQKTSHLQLQPLY 160


>gi|58530842 desmoplakin isoform II [Homo sapiens]
          Length = 2272

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 21/83 (25%), Positives = 32/83 (38%)

Query: 80  ICFYLEVGGLLKDSELLTFSLSRHRSWWRERWPGCLHEEVPAVGLGAPHGQALVSGAGCA 139
           +C Y +   ++   +      +  RS W    PG +   VP+VGL  P    L     C 
Sbjct: 466 LCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCK 525

Query: 140 LEPSYVEALHSCLQILIALLGFV 162
           +E  Y   L    Q+ I +   V
Sbjct: 526 IEQYYEAILALWNQLYINMKSLV 548


>gi|58530840 desmoplakin isoform I [Homo sapiens]
          Length = 2871

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 21/83 (25%), Positives = 32/83 (38%)

Query: 80  ICFYLEVGGLLKDSELLTFSLSRHRSWWRERWPGCLHEEVPAVGLGAPHGQALVSGAGCA 139
           +C Y +   ++   +      +  RS W    PG +   VP+VGL  P    L     C 
Sbjct: 466 LCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSVGLIIPPPNPLAVDLSCK 525

Query: 140 LEPSYVEALHSCLQILIALLGFV 162
           +E  Y   L    Q+ I +   V
Sbjct: 526 IEQYYEAILALWNQLYINMKSLV 548


>gi|46358417 glutamate receptor, metabotropic 3 precursor [Homo
           sapiens]
          Length = 879

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 11/24 (45%), Positives = 17/24 (70%)

Query: 154 ILIALLGFVCGCQVVSVFTEEEDS 177
           + IA LGF+C C VV+VF +  ++
Sbjct: 581 VTIACLGFMCTCMVVTVFIKHNNT 604


>gi|16306483 solute carrier family 26, member 7 isoform a [Homo
           sapiens]
          Length = 656

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 34  WAPILANFVHIIIVILGLFGT-IQYR--LRYVMVYTLWAAVWVTWNVFIICFYLEVG 87
           W P+    V   I+++GL G  IQ+R   +Y  V  +   +WV+  VF ICF   VG
Sbjct: 403 WLPMC---VLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVFTICFAANVG 456


>gi|20336282 solute carrier family 26, member 7 isoform b [Homo
           sapiens]
          Length = 663

 Score = 28.9 bits (63), Expect = 3.2
 Identities = 21/57 (36%), Positives = 30/57 (52%), Gaps = 6/57 (10%)

Query: 34  WAPILANFVHIIIVILGLFGT-IQYR--LRYVMVYTLWAAVWVTWNVFIICFYLEVG 87
           W P+    V   I+++GL G  IQ+R   +Y  V  +   +WV+  VF ICF   VG
Sbjct: 403 WLPMC---VLASIIVVGLKGMLIQFRDLKKYWNVDKIDWGIWVSTYVFTICFAANVG 456


>gi|94538366 transient receptor potential cation channel, subfamily
           M, member 1 [Homo sapiens]
          Length = 1603

 Score = 27.3 bits (59), Expect = 9.4
 Identities = 16/55 (29%), Positives = 26/55 (47%)

Query: 10  LVVLCAFQLVAALERQVFDFLGYQWAPILANFVHIIIVILGLFGTIQYRLRYVMV 64
           LV +  F + A L  Q   ++GY       + +   I +L +FG  +Y   YVM+
Sbjct: 904 LVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIFWYIRVLDIFGVNKYLGPYVMM 958


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.144    0.482 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,319,188
Number of Sequences: 37866
Number of extensions: 362373
Number of successful extensions: 888
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 874
Number of HSP's gapped (non-prelim): 11
length of query: 208
length of database: 18,247,518
effective HSP length: 98
effective length of query: 110
effective length of database: 14,536,650
effective search space: 1599031500
effective search space used: 1599031500
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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