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Search of human proteins with 21361302
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo sapiens]
(427 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 856 0.0
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 341 7e-94
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 336 2e-92
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 333 1e-91
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 332 5e-91
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 330 1e-90
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 319 3e-87
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 319 3e-87
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 319 3e-87
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 319 3e-87
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 319 3e-87
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 319 3e-87
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 319 3e-87
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 319 3e-87
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 319 3e-87
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 319 3e-87
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 319 3e-87
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 319 3e-87
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 241 9e-64
gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ... 216 3e-56
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 184 2e-46
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 179 3e-45
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 178 1e-44
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 177 2e-44
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 170 2e-42
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 169 6e-42
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 164 1e-40
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 164 1e-40
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 164 2e-40
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (... 160 2e-39
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 856 bits (2211), Expect = 0.0
Identities = 427/427 (100%), Positives = 427/427 (100%)
Query: 1 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF 60
MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF
Sbjct: 1 MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAF 60
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG
Sbjct: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ
Sbjct: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT
Sbjct: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR
Sbjct: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS
Sbjct: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK
Sbjct: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
Query: 421 VVDPTKP 427
VVDPTKP
Sbjct: 421 VVDPTKP 427
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 341 bits (875), Expect = 7e-94
Identities = 183/385 (47%), Positives = 256/385 (66%), Gaps = 7/385 (1%)
Query: 44 EGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILE 103
+ +P+ ++ N DFAFR Y + ETP +NIFFSP+S+S + AMLSLGA S +++QIL+
Sbjct: 55 KSTPASQVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQ 114
Query: 104 GLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVY 163
GLGFNLT ES +H+GFQHL+H+L +P L ++GSALF+ L+ A FL + +Y
Sbjct: 115 GLGFNLTHTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLY 174
Query: 164 EAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPF 223
EA++F T+F + IN HVKK+T+GK+VD++ L MVLVN+I+FKA WEKPF
Sbjct: 175 EAEVFSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPF 234
Query: 224 ISSRTTPK-DFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPN 282
T F V E TV VPMM Q ++ + + D L C VL+MDYKGDA FF+LP+
Sbjct: 235 HPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGV-DTELNCFVLQMDYKGDAVAFFVLPS 293
Query: 283 QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLF 342
+GKMR++E+ L+ L +W++ L+KR +E+ +P+FSIS SY L+ ILP++G ++F
Sbjct: 294 KGKMRQLEQALSARTLRKWSHSLQKR----WIEVFIPRFSISASYNLETILPKMGIQNVF 349
Query: 343 SKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHI-LRFNR 401
K AD SGI K+ L+ SK+ HKA LDV E GTEA AAT+ S + + FNR
Sbjct: 350 DKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNR 409
Query: 402 PFLVVIFSTSTQSVLFLGKVVDPTK 426
FL++I + +T +LFLGKV +PTK
Sbjct: 410 TFLMMITNKATDGILFLGKVENPTK 434
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 336 bits (862), Expect = 2e-92
Identities = 189/420 (45%), Positives = 264/420 (62%), Gaps = 18/420 (4%)
Query: 6 YLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANA-DFAFRFYY 64
+LLL LV LL+ LH H E + T +AP++ DF F Y
Sbjct: 4 FLLLCLV-LLSPQGASLHRHHPREMKKRVEDLHVGAT--------VAPSSRRDFTFDLYR 54
Query: 65 LIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHL 124
+AS P ++IFFSP+SIS + AMLSLGA S ++ QILEGLG NL + SE ++HRGFQ L
Sbjct: 55 ALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQL 114
Query: 125 LHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLIND 184
L LN P G + +G+ALF + F++ +Y A F TNF D+ G ++ IND
Sbjct: 115 LQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQIND 174
Query: 185 HVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVP 244
+V K+T+GKIVDL+ L + ++++VNYI+FKA WE F T +DFYV T VRVP
Sbjct: 175 YVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVP 234
Query: 245 MMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNL 304
MM ++ ++H YL DR L C V+ + Y+G+AT FILP++GKM+++E L+ + L +W +
Sbjct: 235 MMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKM 293
Query: 305 LRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFH 364
+KR +LEL+LPKFSI GSY L+++LP LG +++F+ ADLSGI+ ++ S+ H
Sbjct: 294 FKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVH 349
Query: 365 KATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424
KA ++VDE+GT AAAAT F SA+ N L FNRPFL+ I ++LFLGKV P
Sbjct: 350 KAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVD---NNILFLGKVNRP 406
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 333 bits (855), Expect = 1e-91
Identities = 187/422 (44%), Positives = 275/422 (65%), Gaps = 10/422 (2%)
Query: 6 YLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSL-KIAPANADFAFRFYY 64
+L LL G+LA H Q + H +S + + E +P+ +I P +FA R Y
Sbjct: 5 WLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRH-QLSEPAPAYHRITPTITNFALRLYK 63
Query: 65 LIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHL 124
+A++ PG NIFFSP+SIS A+LSLGA +++ + ILEGLGFNLTE E+D+H+GF+ L
Sbjct: 64 ELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSL 122
Query: 125 LHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLIND 184
LHTL LP LE +VG++LFL LK +L+ +Y A F NF D+V T + IND
Sbjct: 123 LHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQIND 182
Query: 185 HVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKD-FYVDENTTVRV 243
+++++T G++VD + E +D MVL NYI+FKA W+ PF +T ++ F+VDE T+++V
Sbjct: 183 YLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQV 242
Query: 244 PMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNN 303
PMM Q +E H +L+D+ L C+VL+++Y+G+A +LP+ GKM+++E L P+ L +W
Sbjct: 243 PMMHQ-KEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQ 301
Query: 304 LLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSF 363
LL L+LHLP+FSISG+Y L+ ILP++G T++ + AD SG+T Q SK
Sbjct: 302 LL----LPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVS 357
Query: 364 HKATLDVDEAGTEAAAATSFAIKFFSAQT-NRHILRFNRPFLVVIFSTSTQSVLFLGKVV 422
HKA +D+ E GTEA AA+ + S T + FNRPFL++++ +TQS+LFLGKVV
Sbjct: 358 HKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVV 417
Query: 423 DP 424
+P
Sbjct: 418 NP 419
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 332 bits (850), Expect = 5e-91
Identities = 188/419 (44%), Positives = 249/419 (59%), Gaps = 4/419 (0%)
Query: 7 LLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLI 66
L LL +GLLA + H + Q + L +A AN DFAF Y +
Sbjct: 5 LPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQL 64
Query: 67 ASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLH 126
+ P KN+ FSPLSIS A A LSLGA + + ++IL+GL FNLTE SE+++H+ FQHLL
Sbjct: 65 VLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLR 124
Query: 127 TLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHV 186
TLN L+ +G+A+F+ L L +F D +Y ++ F T+F D+ +LIND+V
Sbjct: 125 TLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYV 184
Query: 187 KKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMM 246
K TRGKI DL+ +L +MVLVNYI+FKA WE PF T FY+ + V VPMM
Sbjct: 185 KNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMM 244
Query: 247 LQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLR 306
Y D L C+V+ + Y G+A+ FILP+Q KM E+E +L PE L RW + L
Sbjct: 245 SLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLE 304
Query: 307 KRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKA 366
R EL+LPKFSIS Y L+ IL +LG + F+ ADLSGIT + L S+ HKA
Sbjct: 305 FREIG---ELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKA 361
Query: 367 TLDVDEAGTEAAAATSFAIKFFSAQT-NRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424
LDV E GTEA+AAT+ I SA R I+RFNRPFL++I T TQ++ F+ KV +P
Sbjct: 362 VLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 330 bits (847), Expect = 1e-90
Identities = 185/423 (43%), Positives = 265/423 (62%), Gaps = 16/423 (3%)
Query: 6 YLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYL 65
YL+LL++GL A H E +C +S L K++ NADFAF Y
Sbjct: 6 YLVLLVLGLHATIHCA-SPEGKVTACHSSQPNATL--------YKMSSINADFAFNLYRR 56
Query: 66 IASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLL 125
ETP KNIFFSP+SISAA MLS GAC ++++I+E LGFNLT+ ++ GFQHL+
Sbjct: 57 FTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLI 116
Query: 126 HTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDH 185
+LN P LE ++G+ALF+ +LK LAKFLND +YE ++F T+F + Q IN H
Sbjct: 117 CSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSH 176
Query: 186 VKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRT-TPKDFYVDENTTVRVP 244
V+ +T+GK+V L+ +LK + +MVLVNYI+FKA W PF S+T F +D+ TTV+VP
Sbjct: 177 VEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVP 236
Query: 245 MMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNL 304
MM Q E +++L D L C+VL+MDY +A F+LP +G+M +E ++ + L +WN L
Sbjct: 237 MMHQ-MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRL 295
Query: 305 LRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFH 364
L+K ++L +PKFSIS +Y L L ++G +S+ AD SG+T+ L+ S + H
Sbjct: 296 LQK----GWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAH 351
Query: 365 KATLDVDEAGTEAAAATSFAIKFFSAQTNRH-ILRFNRPFLVVIFSTSTQSVLFLGKVVD 423
KA L + E GTEAAA + T H I++ +R F+++I ST+S+LFLGKVV+
Sbjct: 352 KAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVN 411
Query: 424 PTK 426
PT+
Sbjct: 412 PTE 414
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 319 bits (818), Expect = 3e-87
Identities = 169/374 (45%), Positives = 239/374 (63%), Gaps = 8/374 (2%)
Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110
+A AN DFAF Y + + +P KNIF SP+SIS A AMLSLG C H+R+Q+L+GLGFNLT
Sbjct: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170
E SE+++H+GFQHL LE +G+ALFL +L+ L F D YE+++
Sbjct: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230
NF D + IN +VK +T+GKIVDL S L ++VLVNYI+FK W +PF + T
Sbjct: 159 NFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTRE 218
Query: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIE 290
++FYVDE T V+VPMMLQ YLHD LPC +++M+Y G+ TVFFILP++GKM +
Sbjct: 219 ENFYVDETTVVKVPMMLQSSTIS-YLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVI 277
Query: 291 EVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG 350
L+ + + RW+ L +++L++PK +ISG Y L +L +G DLF+ A+ S
Sbjct: 278 AALSRDTINRWSAGLTS----SQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSR 333
Query: 351 ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFST 410
IT+ +L++SK HKA L ++E G + A +T + S ILRFN+PF+++IF
Sbjct: 334 ITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPI---ILRFNQPFIIMIFDH 390
Query: 411 STQSVLFLGKVVDP 424
T S LFL +V++P
Sbjct: 391 FTWSSLFLARVMNP 404
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 319 bits (817), Expect = 3e-87
Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%)
Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60
+ + +LLL GL L L + G++ +++SH + P+ KI P A+FAF
Sbjct: 5 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 59
Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120
Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G
Sbjct: 60 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 119
Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180
FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT +
Sbjct: 120 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240
IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT
Sbjct: 180 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 239
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ +
Sbjct: 240 VKVPMMKRLGMFN-IQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 298
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
+ +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S
Sbjct: 299 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 354
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420
K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK
Sbjct: 355 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 411
Query: 421 VVDPTK 426
VV+PT+
Sbjct: 412 VVNPTQ 417
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 241 bits (615), Expect = 9e-64
Identities = 130/379 (34%), Positives = 221/379 (58%), Gaps = 18/379 (4%)
Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109
++A N D F+ +A PG+NIF SPLSIS A++ML LGA + +I +G FN
Sbjct: 47 ELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNF 104
Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169
++ E D+H GF +++H L L+ +G+ LF+ L+ KFL D Y A+
Sbjct: 105 RKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETIL 164
Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229
TNF + + IND + ++T GKI +L+ + +M+L NYI+F+A W+ F + T
Sbjct: 165 TNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTK 224
Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREI 289
+DF++++N++V+VPMM + + D+ L C++L + Y+ + T FILP++GK++ +
Sbjct: 225 EEDFFLEKNSSVKVPMMFRSGIYQVGYDDK-LSCTILEIPYQKNITAIFILPDEGKLKHL 283
Query: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLS 349
E+ L + RW LL +R +++ +P+ ++G++ L + L +G + +F + DL+
Sbjct: 284 EKGLQVDTFSRWKTLLSRR----VVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLT 339
Query: 350 GITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT----NRHILRFNRPFLV 405
I + L+ ++ HKA L +DE GTE AA T AQT +++ ++P+L+
Sbjct: 340 KIAPHRSLKVGEAVHKAELKMDERGTEGAAGT-------GAQTLPMETPLVVKIDKPYLL 392
Query: 406 VIFSTSTQSVLFLGKVVDP 424
+I+S SVLFLGK+V+P
Sbjct: 393 LIYSEKIPSVLFLGKIVNP 411
>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
B [Homo sapiens]
Length = 335
Score = 216 bits (550), Expect = 3e-56
Identities = 119/247 (48%), Positives = 163/247 (65%), Gaps = 7/247 (2%)
Query: 182 INDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPK-DFYVDENTT 240
IN HVKK+T+GK+VD++ L MVLVN+I+FKA WEKPF T F V E T
Sbjct: 93 INSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVT 152
Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300
V VPMM Q ++ + + D L C VL+MDYKGDA FF+LP++GKMR++E+ L+ L +
Sbjct: 153 VHVPMMHQKEQFAFGV-DTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360
W++ L+KR +E+ +P+FSIS SY L+ ILP++G ++F K AD SGI K+ L+ S
Sbjct: 212 WSHSLQKR----WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVS 267
Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHI-LRFNRPFLVVIFSTSTQSVLFLG 419
K+ HKA LDV E GTEA AAT+ S + + FNR FL++I + +T +LFLG
Sbjct: 268 KATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLG 327
Query: 420 KVVDPTK 426
KV +PTK
Sbjct: 328 KVENPTK 334
Score = 42.7 bits (99), Expect = 6e-04
Identities = 18/41 (43%), Positives = 27/41 (65%)
Query: 44 EGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISA 84
+ +P+ ++ N DFAFR Y + ETP +NIFFSP I++
Sbjct: 55 KSTPASQVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINS 95
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 184 bits (466), Expect = 2e-46
Identities = 130/391 (33%), Positives = 200/391 (51%), Gaps = 21/391 (5%)
Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF--- 107
++ AN F F + ++ NIF+SP+SI++A M+ LGA ++ QI + L F
Sbjct: 4 LSEANTKFMFDLFQQFR-KSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQV 62
Query: 108 --NLTELSES-------DVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLND 158
N TE + + +VH FQ LL N E ++ + LF +FL ++L+
Sbjct: 63 TENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDA 122
Query: 159 TMAVYEAKLFHTNFYDTVG-TIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYF 215
Y+ + T+F + + + IN V+ +T KI +L + + D +VLVN IYF
Sbjct: 123 IKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYF 182
Query: 216 KALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKG-DA 274
K WE F T + F+ ++NT V MM Q ++ L + + VL + YKG D
Sbjct: 183 KGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLED-VQAKVLEIPYKGKDL 241
Query: 275 TVFFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQIL 333
++ +LPN+ ++++EE LT E LM W +L R ++LHLP+F + SY L L
Sbjct: 242 SMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETC--VDLHLPRFKMEESYDLKDTL 299
Query: 334 PRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTN 393
+G ++F+ ADLSG+T L SK HKA ++V E G EAAAAT+ + S+ +
Sbjct: 300 RTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPST 359
Query: 394 RHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424
N PFL I T S+LF G+ P
Sbjct: 360 NEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 179 bits (455), Expect = 3e-45
Identities = 130/392 (33%), Positives = 199/392 (50%), Gaps = 23/392 (5%)
Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN-L 109
++ AN F F + ++ NIF+SP+SI++A M+ LGA ++ QI + L F+ +
Sbjct: 4 LSEANTKFMFDLFQQFR-KSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQV 62
Query: 110 TELS-----------ESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLND 158
TE + +VH FQ LL N E ++ + LF FL ++L+
Sbjct: 63 TENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDA 122
Query: 159 TMAVYEAKLFHTNFYDTVG-TIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYF 215
Y+ + +F + + + IN V+ +T KI +L+ E + + +VLVN IYF
Sbjct: 123 IKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYF 182
Query: 216 KALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWY-LHDRYLPCSVLRMDYKG-D 273
K WEK F T + F+ ++NT + MM Q H+ L D + VL + YKG D
Sbjct: 183 KGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLED--VQAKVLEIPYKGKD 240
Query: 274 ATVFFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQI 332
++ +LPN+ ++++EE LT E LM W +L R +++LHLP+F + SY L
Sbjct: 241 LSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRE--TRVDLHLPRFKVEESYDLKDT 298
Query: 333 LPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT 392
L +G D+F+ ADLSG+T + L S HKA ++V E G EAAAAT+ S +
Sbjct: 299 LRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTS 358
Query: 393 NRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424
N PFL I T S+LF G+ P
Sbjct: 359 TNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 178 bits (451), Expect = 1e-44
Identities = 131/387 (33%), Positives = 202/387 (52%), Gaps = 22/387 (5%)
Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109
+++ AN FA + ++ P NIF SP SIS+A AM+ LG ++ +Q+ + FN
Sbjct: 3 QLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNT 62
Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169
E +VH FQ L +N G ++ + L+ FL +FL T Y A L
Sbjct: 63 VE----EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLAS 118
Query: 170 TNF-YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVL--MVLVNYIYFKALWEKPFISS 226
+F + + + IN VK +T GKI +L++ D + +VLVN IYFK W+ F+
Sbjct: 119 VDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKE 178
Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEH-HWYLHDRYLPCSVLRMDYKG-DATVFFILPNQG 284
TT F +++ V MM Q ++ + Y+ D L C VL + Y+G + ++ +LP+
Sbjct: 179 ATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIED--LKCRVLELPYQGEELSMVILLPDDI 236
Query: 285 K-----MREIEEVLTPEMLMRWNNLLRKRNF-YKKLELHLPKFSISGSYVLDQILPRLGF 338
+ +++IEE LT E L W + N + ++ + LP+F + SY L+ L RLG
Sbjct: 237 EDESTGLKKIEEQLTLEKLHEWT---KPENLDFIEVNVSLPRFKLEESYTLNSDLARLGV 293
Query: 339 TDLF-SKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHIL 397
DLF S ADLSG++ + + SK HK+ ++V+E GTEAAAAT+ I F
Sbjct: 294 QDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATA-GIATFCMLMPEENF 352
Query: 398 RFNRPFLVVIFSTSTQSVLFLGKVVDP 424
+ PFL I S+ S+LFLG+ P
Sbjct: 353 TADHPFLFFIRHNSSGSILFLGRFSSP 379
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 177 bits (449), Expect = 2e-44
Identities = 130/386 (33%), Positives = 203/386 (52%), Gaps = 17/386 (4%)
Query: 50 KIAPANADFAFRFY-YLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108
+++ AN+ FA FY +L S+ NIF SPLSIS A+AM LGAC+ + Q++E F+
Sbjct: 82 ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFD 141
Query: 109 -LTELSESDVHRGFQHLLHTLNLPGHGLETRVGS-ALFLSHNLKFLAKFLNDTMAVYEAK 166
++E + +H F L L + V + LF +L F + + + VY AK
Sbjct: 142 TISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAK 201
Query: 167 LFHTNFYDTVGTIQL-INDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPF 223
L +F + + IN V +T G+I D++ + + ++VLVN IYFK LW+ F
Sbjct: 202 LQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKF 261
Query: 224 ISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGD-ATVFFILPN 282
T + FY + + MM Q+ + + VL + +KGD T+ ILP
Sbjct: 262 SPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE--GTQVLELPFKGDDITMVLILPK 319
Query: 283 QGK-MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDL 341
K + ++E+ LTPE+L W + L + L +H+P+F I + L + L +G DL
Sbjct: 320 PEKSLAKVEKELTPEVLQEWLDELEEM----MLVVHMPRFRIEDGFSLKEQLQDMGLVDL 375
Query: 342 FS-KWADLSGITKQQK--LEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILR 398
FS + + L GI + + L S +FHKA L+V+E G+EAAA+T+ I S NR +
Sbjct: 376 FSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFK 435
Query: 399 FNRPFLVVIFSTSTQSVLFLGKVVDP 424
NRPFLV I +++F+G+V +P
Sbjct: 436 ANRPFLVFIREVPLNTIIFMGRVANP 461
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 170 bits (431), Expect = 2e-42
Identities = 119/380 (31%), Positives = 194/380 (51%), Gaps = 13/380 (3%)
Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110
++ A+ FA R ++ + P N+F SP+SIS+A AM+ LGA ++ +Q+ + L N
Sbjct: 4 LSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN-- 61
Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170
+E D+HR FQ LL +N G R + LF +FL+ F + Y A+L
Sbjct: 62 --TEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKEL 119
Query: 171 NFYDTV-GTIQLINDHVKKETRGKIVDLV--SELKKDVLMVLVNYIYFKALWEKPFISSR 227
+F + + IN V K+T GKI +L+ S + + +VLVN IYFK W +PF +
Sbjct: 120 SFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETY 179
Query: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDY-KGDATVFFILPNQG-K 285
T F +++ V MM Q+ H + +L + Y + + ++ +LP+ G +
Sbjct: 180 TREMPFKINQEEQRPVQMMYQEATFK-LAHVGEVRAQLLELPYARKELSLLVLLPDDGVE 238
Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345
+ +E+ LT E L W ++ ++E+ LPKF + Y ++ +L LG D F +
Sbjct: 239 LSTVEKSLTFEKLTAWTKPDCMKS--TEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQG 296
Query: 346 -ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404
ADLS ++ ++ L SK HK+ ++V+E GTEAAAA+S + + + PFL
Sbjct: 297 KADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFL 356
Query: 405 VVIFSTSTQSVLFLGKVVDP 424
I S+LF G+ P
Sbjct: 357 FFIRHNRANSILFCGRFSSP 376
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 169 bits (427), Expect = 6e-42
Identities = 126/383 (32%), Positives = 201/383 (52%), Gaps = 19/383 (4%)
Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110
+A AN FA + + KN+FFSP+S+S A AM+ +GA ++ +Q+ + L FN +
Sbjct: 4 LAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKS 62
Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170
D+H+GFQ LL +N G R+ + LF + FL+ F + Y+A++
Sbjct: 63 G-GGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEEL 121
Query: 171 NFYDTV-GTIQLINDHVKKETRGKIVDLVSELKKDVL--MVLVNYIYFKALWEKPFISSR 227
+F V + + IN V ++T GKI +L+S D L +VLVN +YF+ W++ F
Sbjct: 122 DFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKEN 181
Query: 228 TTPKDFYVDENTTVRVPMML-QDQEHHWYLHDRYLPCSVLRMDYKG-DATVFFILPNQ-G 284
T + F V +N V MM Q Y+ + + +L + Y G + + +LP++
Sbjct: 182 TEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIF--TQILVLPYVGKELNMIIMLPDETT 239
Query: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344
+R +E+ LT E + W L +++E+ LP+F + SY ++ +L LG TD F
Sbjct: 240 DLRTVEKELTYEKFVEWTRLDMMDE--EEVEVSLPRFKLEESYDMESVLRNLGMTDAFEL 297
Query: 345 W-ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRF--NR 401
AD SG++ Q L SK HK+ ++V+E GTEAAAAT+ + A R + RF +
Sbjct: 298 GKADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCA---RFVPRFCADH 353
Query: 402 PFLVVIFSTSTQSVLFLGKVVDP 424
PFL I + T +LF G+ P
Sbjct: 354 PFLFFIQHSKTNGILFCGRFSSP 376
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 164 bits (416), Expect = 1e-40
Identities = 113/381 (29%), Positives = 195/381 (51%), Gaps = 17/381 (4%)
Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109
++A ++F F I+ G N+ FSP +S A L LGA + +QI GL
Sbjct: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132
Query: 110 TELSESDVHRG-FQHLLHTLNLPGHGLETRV--GSALFLSHNLKFLAKFLNDTMAVYEAK 166
+ ++ + F+ L TL+ LE + GS F+ + F N + ++ +
Sbjct: 133 LKPTKPGLLPSLFKGLRETLS---RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189
Query: 167 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 226
NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF
Sbjct: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 249
Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFIL-PNQGK 285
T F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L G
Sbjct: 250 FTEVDTFHLDKYKTIKVPMMYGAGKFA-STFDKNFRCHVLKLPYQGNATMLVVLMEKMGD 308
Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345
+E+ LT +++ W ++ RN +E+ PKF + Y + ++L ++G +FS +
Sbjct: 309 HLALEDYLTTDLVETWLRNMKTRN----MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF 364
Query: 346 ADLSGITKQ-QKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404
ADLS ++ + L+ S+ + ++VDE GTEA A I +S +++ +RPF
Sbjct: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFH 421
Query: 405 VVIFSTSTQSVLFLGKVVDPT 425
+I+ ++ +LFLG+VV+PT
Sbjct: 422 FMIYEETSGMLLFLGRVVNPT 442
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 164 bits (416), Expect = 1e-40
Identities = 113/381 (29%), Positives = 195/381 (51%), Gaps = 17/381 (4%)
Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109
++A ++F F I+ G N+ FSP +S A L LGA + +QI GL
Sbjct: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132
Query: 110 TELSESDVHRG-FQHLLHTLNLPGHGLETRV--GSALFLSHNLKFLAKFLNDTMAVYEAK 166
+ ++ + F+ L TL+ LE + GS F+ + F N + ++ +
Sbjct: 133 LKPTKPGLLPSLFKGLRETLS---RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 189
Query: 167 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 226
NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF
Sbjct: 190 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 249
Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFIL-PNQGK 285
T F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L G
Sbjct: 250 FTEVDTFHLDKYKTIKVPMMYGAGKFA-STFDKNFRCHVLKLPYQGNATMLVVLMEKMGD 308
Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345
+E+ LT +++ W ++ RN +E+ PKF + Y + ++L ++G +FS +
Sbjct: 309 HLALEDYLTTDLVETWLRNMKTRN----MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF 364
Query: 346 ADLSGITKQ-QKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404
ADLS ++ + L+ S+ + ++VDE GTEA A I +S +++ +RPF
Sbjct: 365 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP---VIKVDRPFH 421
Query: 405 VVIFSTSTQSVLFLGKVVDPT 425
+I+ ++ +LFLG+VV+PT
Sbjct: 422 FMIYEETSGMLLFLGRVVNPT 442
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 164 bits (414), Expect = 2e-40
Identities = 123/402 (30%), Positives = 196/402 (48%), Gaps = 36/402 (8%)
Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110
+A + FA +A GKNIFFS SIS + ++ LGA + +Q+ + L FN
Sbjct: 4 LATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRD 63
Query: 111 E-----------------LSESD-VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFL 152
+ LS S+ +H FQ L+ + P + +A++ F
Sbjct: 64 QGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFH 123
Query: 153 AKFLNDTMAVYEAKLFHTNFYDTVGTIQL-INDHVKKETRGKIVDLVSELKKD--VLMVL 209
K+L D + A+ NF + I+ IN V+++T GKI +L+ + D M+L
Sbjct: 124 NKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMIL 183
Query: 210 VNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMD 269
VN +YFK +WE F+ TT K F ++E T+ V MM ++ H + H L++
Sbjct: 184 VNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIF-HIEKPKAVGLQLY 242
Query: 270 YKG-DATVFFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSY 327
YK D ++ +LP + ++E+ +T E L W + + +++LHLPKF + SY
Sbjct: 243 YKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELY--EVQLHLPKFKLEDSY 300
Query: 328 VLDQILPRLGFTDLFSK-WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAAT----S 382
L L +G +D FS+ AD SG++ + L S FHKA ++++E GTEAAA +
Sbjct: 301 DLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEID 360
Query: 383 FAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424
I+ S + N N PFL I T ++LF G++ P
Sbjct: 361 IRIRVPSIEFNA-----NHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 12 [Homo sapiens]
Length = 405
Score = 160 bits (406), Expect = 2e-39
Identities = 128/408 (31%), Positives = 196/408 (48%), Gaps = 40/408 (9%)
Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110
+ AN F F + I + KNIFFSPLS+SAA M+ LGA S S QI E L FN
Sbjct: 4 LVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEF 63
Query: 111 ELSESD----------------------VHRGFQHLLHTLNLPGHGLETRVGSALFLSHN 148
+ES V F LL L+ + + L+
Sbjct: 64 SQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYGEQE 123
Query: 149 LKFLAKFLNDTMAVYEAKLFHTNFY-DTVGTIQLINDHVKKETRGKIVDLVSE--LKKDV 205
++L+ + Y + +F + + Q IN V+ +++GKI +L S+ + +
Sbjct: 124 FPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAET 183
Query: 206 LMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSV 265
++VLVN +YFKA WE F T F ++ N V MM Q + + + +
Sbjct: 184 VLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEE-VKAQI 242
Query: 266 LRMDY-KGDATVFFILPNQGK-----MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLP 319
L M Y KG ++F +LP+ K + E+E +T E ++ W++ + + + L P
Sbjct: 243 LEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSS--SENMSEESVVLSFP 300
Query: 320 KFSISGSYVLDQILPRLGFTDLFSKW-ADLSGITKQQKLEASKSFHKATLDVDEAGTEAA 378
+F++ SY L+ IL +G TD+F + ADL+GI+ L SK HK ++VDE GT+AA
Sbjct: 301 RFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAA 360
Query: 379 AATSFAIKFFSAQTNRHILRF--NRPFLVVIFSTSTQSVLFLGKVVDP 424
AAT + S ++ R + F N PFL I TQ++LF G+V P
Sbjct: 361 AATGAVV---SERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,234,557
Number of Sequences: 37866
Number of extensions: 639541
Number of successful extensions: 1516
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1237
Number of HSP's gapped (non-prelim): 79
length of query: 427
length of database: 18,247,518
effective HSP length: 105
effective length of query: 322
effective length of database: 14,271,588
effective search space: 4595451336
effective search space used: 4595451336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.