Guide to the Human Genome
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Search of human proteins with 212274477

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|212274477 lanthionine synthetase C-like protein 1 [Homo
sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174445 lanthionine synthetase C-like protein 1 [Homo sapiens]     839   0.0  
gi|212274477 lanthionine synthetase C-like protein 1 [Homo sapiens]   839   0.0  
gi|212274337 lanthionine synthetase C-like protein 1 [Homo sapiens]   839   0.0  
gi|8923911 LanC lantibiotic synthetase component C-like 2 [Homo ...   483   e-136
gi|38348330 LanC lantibiotic synthetase component C-like 3 [Homo...   177   1e-44
gi|4557599 glucose-6-phosphatase, catalytic subunit [Homo sapiens]     30   2.9  
gi|22218355 WAP four-disulfide core domain 11 precursor [Homo sa...    29   8.6  

>gi|5174445 lanthionine synthetase C-like protein 1 [Homo sapiens]
          Length = 399

 Score =  839 bits (2168), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT 60
           MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT
Sbjct: 1   MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT 60

Query: 61  GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL 120
           GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL
Sbjct: 61  GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL 120

Query: 121 YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ 180
           YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ
Sbjct: 121 YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ 180

Query: 181 QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL 240
           QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL
Sbjct: 181 QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL 240

Query: 241 HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC 300
           HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC
Sbjct: 241 HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC 300

Query: 301 DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE 360
           DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE
Sbjct: 301 DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE 360

Query: 361 HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL 399
           HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL
Sbjct: 361 HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL 399


>gi|212274477 lanthionine synthetase C-like protein 1 [Homo sapiens]
          Length = 399

 Score =  839 bits (2168), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT 60
           MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT
Sbjct: 1   MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT 60

Query: 61  GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL 120
           GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL
Sbjct: 61  GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL 120

Query: 121 YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ 180
           YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ
Sbjct: 121 YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ 180

Query: 181 QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL 240
           QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL
Sbjct: 181 QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL 240

Query: 241 HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC 300
           HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC
Sbjct: 241 HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC 300

Query: 301 DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE 360
           DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE
Sbjct: 301 DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE 360

Query: 361 HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL 399
           HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL
Sbjct: 361 HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL 399


>gi|212274337 lanthionine synthetase C-like protein 1 [Homo sapiens]
          Length = 399

 Score =  839 bits (2168), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT 60
           MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT
Sbjct: 1   MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT 60

Query: 61  GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL 120
           GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL
Sbjct: 61  GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL 120

Query: 121 YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ 180
           YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ
Sbjct: 121 YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ 180

Query: 181 QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL 240
           QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL
Sbjct: 181 QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL 240

Query: 241 HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC 300
           HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC
Sbjct: 241 HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC 300

Query: 301 DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE 360
           DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE
Sbjct: 301 DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE 360

Query: 361 HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL 399
           HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL
Sbjct: 361 HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL 399


>gi|8923911 LanC lantibiotic synthetase component C-like 2 [Homo
           sapiens]
          Length = 450

 Score =  483 bits (1244), Expect = e-136
 Identities = 231/426 (54%), Positives = 304/426 (71%), Gaps = 27/426 (6%)

Query: 1   MAQRAFPNPYADYNKS----LAEGYFDAAGRLTP-------------------EFSQRLT 37
           M +RAF NP+ DY  +    LA G  +  G + P                    F +R+ 
Sbjct: 19  MEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPGLPFHQDGKIIHNFIRRIQ 78

Query: 38  NKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLN 97
            KI++LLQQME GLK+ADP D + YTGW GIA+LYL LY V  D  YL  +  YVK++L 
Sbjct: 79  TKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVTCDQTYLLRSLDYVKRTLR 138

Query: 98  CLTKRSITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKI----DPHAPNEMLY 153
            L  R +TFLCGDAGPLAV AV+YHK+ ++ ++++C+T+L+ L +     +   P+E+LY
Sbjct: 139 NLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQLQRSVVCQESDLPDELLY 198

Query: 154 GRIGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEY 213
           GR GY+YALL++N   G   + +S I+++   I+ SG+ L+R+   T + PL+Y+W+++ 
Sbjct: 199 GRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSREERKTERCPLLYQWHRKQ 258

Query: 214 YVGAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLV 273
           YVGAAHG+AGIYY LMQP+ +V Q  L  +VKPS+DYV   KF SGNYP  + +  D LV
Sbjct: 259 YVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKKFRSGNYPSSLSNETDRLV 318

Query: 274 HWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFL 333
           HWCHGAPGVI+ML+QAYKVF+EEKYL +A +C+DVIWQ GLL+KGYG+CHG+AGN Y+FL
Sbjct: 319 HWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLLRKGYGICHGTAGNGYSFL 378

Query: 334 TLYNLTQDMKYLYRACKFAEWCLEYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKAR 393
           +LY LTQD KYLYRACKFAEWCL+YG HGCR PD P+SLFEGMAG I+FL+D+L P  +R
Sbjct: 379 SLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEGMAGAIHFLSDVLGPETSR 438

Query: 394 FPAFEL 399
           FPAFEL
Sbjct: 439 FPAFEL 444


>gi|38348330 LanC lantibiotic synthetase component C-like 3 [Homo
           sapiens]
          Length = 388

 Score =  177 bits (449), Expect = 1e-44
 Identities = 120/376 (31%), Positives = 180/376 (47%), Gaps = 43/376 (11%)

Query: 3   QRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGTG- 61
           +R F N + DY  SL  G  + A       +  +T  I  +LQ++      A+ R  T  
Sbjct: 4   KRCFANRFDDYQGSLLAGQCEEA------VAPLVTATIERILQELPPLGGGAEARGATAG 57

Query: 62  --------YTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCL-------------T 100
                   Y G AG+A +   LY V   P +      Y++ +   +              
Sbjct: 58  ASACQGGLYGGVAGVAYM---LYHVSQSPLFATARERYLRSAKRLIDACARAEEWGEPDA 114

Query: 101 KRSITFLCGDAGPLAVAAVLYHKMNNEKQAED-----CITRLIHLNKIDPHAPNEMLYGR 155
                FL G AG  AVA ++YH +      +       +  +           +E+  GR
Sbjct: 115 DTRAAFLLGGAGVYAVATLVYHALGRSDYVQPLGKFRALCAVCAPVSFLECGSDELFVGR 174

Query: 156 IGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEYYV 215
            GY+ A L + +    E +  + I+ IC+ IL SG+  A K+      PLMY +Y   Y+
Sbjct: 175 AGYLCAALVLKQKLAQEVLTPAQIKSICQAILDSGKQYAIKKR--KPFPLMYSYYGTEYL 232

Query: 216 GAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLKFPSGNYPPCIGDN---RDLL 272
           GAAHGL+ I   L+     +       LV  SVD++ + +  + N+PP +G+     + L
Sbjct: 233 GAAHGLSSILQMLLSYHEHLKPSD-RELVWQSVDFLMEQE-QNCNWPPELGETIERENEL 290

Query: 273 VHWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAF 332
           VHWCHGAPG+ Y+  +AY V ++ +YL    +C ++ WQ GLLKKG G+CHG AG+AY F
Sbjct: 291 VHWCHGAPGIAYLFAKAYLVSKKPQYLDTCIRCGELTWQKGLLKKGPGICHGVAGSAYVF 350

Query: 333 LTLYNLTQDMKYLYRA 348
           L LY LT + KY+YRA
Sbjct: 351 LLLYRLTGNSKYIYRA 366


>gi|4557599 glucose-6-phosphatase, catalytic subunit [Homo sapiens]
          Length = 357

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 14/37 (37%), Positives = 22/37 (59%), Gaps = 4/37 (10%)

Query: 216 GAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVC 252
           G A G AG+YY ++  +L + QGK    +KP+  + C
Sbjct: 118 GHAMGTAGVYYVMVTSTLSIFQGK----IKPTYRFRC 150


>gi|22218355 WAP four-disulfide core domain 11 precursor [Homo
           sapiens]
          Length = 87

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 267 DNRDLLVHWCHGAPGVIYMLIQAYKVFR--EEKYLCDAYQCADVIW 310
           D ++LL+  C G P V     +  K FR  ++ Y C    C ++ W
Sbjct: 33  DRKELLLEECWGKPNVKECTNKCSKAFRCKDKNYTCCWTYCGNICW 78


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,026,606
Number of Sequences: 37866
Number of extensions: 711866
Number of successful extensions: 1274
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1252
Number of HSP's gapped (non-prelim): 8
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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