Guide to the Human Genome
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Search of human proteins with 20302153

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20302153 hyaluronan synthase 3 isoform a [Homo sapiens]
         (553 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20302153 hyaluronan synthase 3 isoform a [Homo sapiens]           1126   0.0  
gi|4885391 hyaluronan synthase 2 [Homo sapiens]                       821   0.0  
gi|167466171 hyaluronan synthase 1 [Homo sapiens]                     619   e-177
gi|20302155 hyaluronan synthase 3 isoform b [Homo sapiens]            493   e-139
gi|52317104 olfactory receptor, family 5, subfamily AR, member 1...    30   4.4  
gi|52317209 olfactory receptor, family 2, subfamily M, member 7 ...    30   4.4  
gi|4503947 glucagon receptor [Homo sapiens]                            30   5.8  

>gi|20302153 hyaluronan synthase 3 isoform a [Homo sapiens]
          Length = 553

 Score = 1126 bits (2913), Expect = 0.0
 Identities = 553/553 (100%), Positives = 553/553 (100%)

Query: 1   MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS 60
           MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS
Sbjct: 1   MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS 60

Query: 61  LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM 120
           LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM
Sbjct: 61  LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM 120

Query: 121 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA 180
           VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA
Sbjct: 121 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA 180

Query: 181 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG 240
           STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG
Sbjct: 181 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG 240

Query: 241 VGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLE 300
           VGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLE
Sbjct: 241 VGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLE 300

Query: 301 DWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKS 360
           DWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKS
Sbjct: 301 DWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKS 360

Query: 361 YFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVG 420
           YFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVG
Sbjct: 361 YFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVG 420

Query: 421 IIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIG 480
           IIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIG
Sbjct: 421 IIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIG 480

Query: 481 LIPVSIWVAVLLGGLAYTAYCQDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCG 540
           LIPVSIWVAVLLGGLAYTAYCQDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCG
Sbjct: 481 LIPVSIWVAVLLGGLAYTAYCQDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRCG 540

Query: 541 KKPEQYSLAFAEV 553
           KKPEQYSLAFAEV
Sbjct: 541 KKPEQYSLAFAEV 553


>gi|4885391 hyaluronan synthase 2 [Homo sapiens]
          Length = 552

 Score =  821 bits (2120), Expect = 0.0
 Identities = 385/544 (70%), Positives = 468/544 (86%), Gaps = 9/544 (1%)

Query: 9   LRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHR 68
           LR++GT+LF +++L GI AAY+ GYQFI T+ +Y SFGLYGA L  HL+IQSLFAFLEHR
Sbjct: 10  LRIIGTTLFGVSLLLGITAAYIVGYQFIQTDNYYFSFGLYGAFLASHLIIQSLFAFLEHR 69

Query: 69  RMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVMVVDGNRQE 128
           +M+++   L+ P     +VALCIAAYQEDPDYLRKCL+S +R+++P +KVVMV+DGN ++
Sbjct: 70  KMKKS---LETPIKLNKTVALCIAAYQEDPDYLRKCLQSVKRLTYPGIKVVMVIDGNSED 126

Query: 129 DAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRASTFSCIMQ 188
           D YM+DIF EV+G  +++  ++W++NFHE G GET+ S +E    V  +V ++   CIMQ
Sbjct: 127 DLYMMDIFSEVMG-RDKSATYIWKNNFHEKGPGETDESHKESSQHVTQLVLSNKSICIMQ 185

Query: 189 KWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGGVGGDVQIL 248
           KWGGKREVMYTAF+ALG SVDY+QVCDSDT+LDPA ++EM++VLEEDP VGGVGGDVQIL
Sbjct: 186 KWGGKREVMYTAFRALGRSVDYVQVCDSDTMLDPASSVEMVKVLEEDPMVGGVGGDVQIL 245

Query: 249 NKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQQFLEDWYHQKFL 308
           NKYDSWISFLSSVRYWMAFN+ERACQSYFGCVQCISGPLGMYRNSLL +F+EDWY+Q+F+
Sbjct: 246 NKYDSWISFLSSVRYWMAFNIERACQSYFGCVQCISGPLGMYRNSLLHEFVEDWYNQEFM 305

Query: 309 GSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTRWSKSYFREWLYN 368
           G++CSFGDDRHLTNRVLSLGY TKYTARSKCLTETP +YLRWLNQQTRWSKSYFREWLYN
Sbjct: 306 GNQCSFGDDRHLTNRVLSLGYATKYTARSKCLTETPIEYLRWLNQQTRWSKSYFREWLYN 365

Query: 369 SLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYAC 428
           ++WFHKHHLWMTYE+++TGFFPFFLIATVIQLFYRG+IWNILLFLLTVQLVG+IK+++A 
Sbjct: 366 AMWFHKHHLWMTYEAIITGFFPFFLIATVIQLFYRGKIWNILLFLLTVQLVGLIKSSFAS 425

Query: 429 FLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWV 488
            LRGN  M+FMSLYS+LYMSSLLPAK+FAIATINK+GWGTSGRKTIVVNFIGLIPVS+W 
Sbjct: 426 CLRGNIVMVFMSLYSVLYMSSLLPAKMFAIATINKAGWGTSGRKTIVVNFIGLIPVSVWF 485

Query: 489 AVLLGGLAYTAYCQDL--FSETELAFLVSGAILYGCYWVALLMLYLAIIARRCG--KKPE 544
            +LLGG+ +T Y +    FSE++   L+ G +LY CYWV LL LY+ +I  +CG  KK +
Sbjct: 486 TILLGGVIFTIYKESKRPFSESKQTVLIVGTLLYACYWVMLLTLYVVLI-NKCGRRKKGQ 544

Query: 545 QYSL 548
           QY +
Sbjct: 545 QYDM 548


>gi|167466171 hyaluronan synthase 1 [Homo sapiens]
          Length = 578

 Score =  619 bits (1596), Expect = e-177
 Identities = 310/556 (55%), Positives = 392/556 (70%), Gaps = 21/556 (3%)

Query: 10  RVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQSLFAFLEHRR 69
           R V T  FAL +LG +  AY  G          L+FGLYGA L  HL+ QSLFA+LEHRR
Sbjct: 21  RRVLTIAFALLILGLMTWAYAAGVPLASDRYGLLAFGLYGAFLSAHLVAQSLFAYLEHRR 80

Query: 70  MRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPD--LKVVMVVDGNRQ 127
           +  A +   L +    SVAL I+AYQEDP YLR+CL SA+ + +P   L+V+MVVDGNR 
Sbjct: 81  VAAAARG-PLDAATARSVALTISAYQEDPAYLRQCLASARALLYPRARLRVLMVVDGNRA 139

Query: 128 EDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDR-----------VRD 176
           ED YM+D+F EV    + A + VW  N+H+  E     ++  G  R           V  
Sbjct: 140 EDLYMVDMFREVFADEDPATY-VWDGNYHQPWEPAAAGAVGAGAYREVEAEDPGRLAVEA 198

Query: 177 VVRASTFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDP 236
           +VR     C+ Q+WGGKREVMYTAFKALGDSVDY+QVCDSDT LDP   +E++RVL+EDP
Sbjct: 199 LVRTRRCVCVAQRWGGKREVMYTAFKALGDSVDYVQVCDSDTRLDPMALLELVRVLDEDP 258

Query: 237 QVGGVGGDVQILNKYDSWISFLSSVRYWMAFNVERACQSYFGCVQCISGPLGMYRNSLLQ 296
           +VG VGGDV+ILN  DSW+SFLSS+RYW+AFNVERACQSYF CV CISGPLG+YRN+LLQ
Sbjct: 259 RVGAVGGDVRILNPLDSWVSFLSSLRYWVAFNVERACQSYFHCVSCISGPLGLYRNNLLQ 318

Query: 297 QFLEDWYHQKFLGSKCSFGDDRHLTNRVLSLGYRTKYTARSKCLTETPTKYLRWLNQQTR 356
           QFLE WY+QKFLG+ C+FGDDRHLTNR+LS+GY TKYT+RS+C +ETP+ +LRWL+QQTR
Sbjct: 319 QFLEAWYNQKFLGTHCTFGDDRHLTNRMLSMGYATKYTSRSRCYSETPSSFLRWLSQQTR 378

Query: 357 WSKSYFREWLYNSLWFHKHHLWMTYESVVTGFFPFFLIATVIQLFYRGRIWNILLFLLTV 416
           WSKSYFREWLYN+LW+H+HH WMTYE+VV+G FPFF+ ATV++LFY GR W +L  LL V
Sbjct: 379 WSKSYFREWLYNALWWHRHHAWMTYEAVVSGLFPFFVAATVLRLFYAGRPWALLWVLLCV 438

Query: 417 QLVGIIKATYACFLRGNAEMIFMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVV 476
           Q V + KA +A +LRG   M+ +SLY+ LYM  LLPAK  A+ T+N+SGWGTSGR+ +  
Sbjct: 439 QGVALAKAAFAAWLRGCLRMVLLSLYAPLYMCGLLPAKFLALVTMNQSGWGTSGRRKLAA 498

Query: 477 NFIGLIPVSIWVAVLLGGLAYT------AYCQDLFSETELAFLVSGAILYGCYWVALLML 530
           N++ L+P+++W  +LLGGL  +      A         E   L +GA  Y  YWVA+L L
Sbjct: 499 NYVPLLPLALWALLLLGGLVRSVAHEARADWSGPSRAAEAYHLAAGAGAYVGYWVAMLTL 558

Query: 531 YLAIIARRCGKKPEQY 546
           Y   + R C ++   Y
Sbjct: 559 YWVGVRRLCRRRTGGY 574


>gi|20302155 hyaluronan synthase 3 isoform b [Homo sapiens]
          Length = 281

 Score =  493 bits (1270), Expect = e-139
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS 60
           MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS
Sbjct: 1   MPVQLTTALRVVGTSLFALAVLGGILAAYVTGYQFIHTEKHYLSFGLYGAILGLHLLIQS 60

Query: 61  LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM 120
           LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM
Sbjct: 61  LFAFLEHRRMRRAGQALKLPSPRRGSVALCIAAYQEDPDYLRKCLRSAQRISFPDLKVVM 120

Query: 121 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA 180
           VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA
Sbjct: 121 VVDGNRQEDAYMLDIFHEVLGGTEQAGFFVWRSNFHEAGEGETEASLQEGMDRVRDVVRA 180

Query: 181 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG 240
           STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG
Sbjct: 181 STFSCIMQKWGGKREVMYTAFKALGDSVDYIQVCDSDTVLDPACTIEMLRVLEEDPQVGG 240

Query: 241 VGGDVQ 246
           VGGDVQ
Sbjct: 241 VGGDVQ 246


>gi|52317104 olfactory receptor, family 5, subfamily AR, member 1
           [Homo sapiens]
          Length = 310

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 36/143 (25%), Positives = 55/143 (38%), Gaps = 13/143 (9%)

Query: 388 FFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLLYM 447
           FF  FLI  ++ +   G I  I+L     QL      T   F   N     +S   L Y 
Sbjct: 27  FFVVFLIVYLVNVV--GNIGMIILITTDTQL-----HTPMYFFLCN-----LSFVDLGYS 74

Query: 448 SSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYCQDLFSE 507
           S++ P  +    T N      S   T    F+G +    +V   +    + A C+ L   
Sbjct: 75  SAIAPRMLADFLT-NHKVISFSSCATQFAFFVGFVDAECYVLAAMAYGRFVAICRPLHYS 133

Query: 508 TELAFLVSGAILYGCYWVALLML 530
           T ++  V  A++ G Y   L+ L
Sbjct: 134 TFMSKQVCLALMLGSYLAGLVSL 156


>gi|52317209 olfactory receptor, family 2, subfamily M, member 7
           [Homo sapiens]
          Length = 312

 Score = 30.4 bits (67), Expect = 4.4
 Identities = 30/119 (25%), Positives = 50/119 (42%), Gaps = 11/119 (9%)

Query: 386 TGFFPFFLIATVIQLFYRGRIWNILLFLLTVQLVGIIKATYACFLRGNAEMIFMSLYSLL 445
           T  F FFL+  +  + + G    +LL  L  QL      T   FL        +SL  L+
Sbjct: 23  THTFLFFLVLAIFSVAFMGNSIMVLLIYLDTQL-----HTPMYFLLSQ-----LSLMDLM 72

Query: 446 YMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAYTAYCQDL 504
            + + +P   F   + +KS    +G  T +  +I L+    ++  ++    YTA C  L
Sbjct: 73  LICTTVPKMAFNYLSGSKS-ISMAGCATQIFFYISLLGSECFLLAVMSYDRYTAICHPL 130


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 2/102 (1%)

Query: 438 FMSLYSLLYMSSLLPAKIFAIATINKSGWGTSGRKTIVVNFIGLIPVSIWVAVLLGGLAY 497
           F  +Y++ Y  SL  A + A+A +         R  I  N      +     +++ GL  
Sbjct: 141 FQVMYTVGYSLSL-GALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLR 199

Query: 498 TAYCQDLFSETELAFLVSGAILYGCYWVALLMLYLAIIARRC 539
           T Y Q +  +  ++  +S   + GC   A+ M Y  I+A  C
Sbjct: 200 TRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQY-GIVANYC 240


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,860,212
Number of Sequences: 37866
Number of extensions: 831975
Number of successful extensions: 2047
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2034
Number of HSP's gapped (non-prelim): 8
length of query: 553
length of database: 18,247,518
effective HSP length: 107
effective length of query: 446
effective length of database: 14,195,856
effective search space: 6331351776
effective search space used: 6331351776
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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