Guide to the Human Genome
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Search of human proteins with 190014632

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190014632
UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase isoform
1 [Homo sapiens]
         (753 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190014632 UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosa...  1503   0.0  
gi|4885285 UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosami...  1438   0.0  
gi|157671949 rearranged L-myc fusion [Homo sapiens]                    35   0.34 
gi|4501915 ADAM metallopeptidase domain 9 isoform 1 precursor [H...    34   0.57 
gi|148747437 Mob4B protein [Homo sapiens]                              33   0.75 
gi|27735029 MOB1, Mps One Binder kinase activator-like 1A [Homo ...    32   2.2  

>gi|190014632
           UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine
           kinase isoform 1 [Homo sapiens]
          Length = 753

 Score = 1503 bits (3892), Expect = 0.0
 Identities = 753/753 (100%), Positives = 753/753 (100%)

Query: 1   METYGYLQRESCFQGPHELYFKNLSKRNKQIMEKNGNNRKLRVCVATCNRADYSKLAPIM 60
           METYGYLQRESCFQGPHELYFKNLSKRNKQIMEKNGNNRKLRVCVATCNRADYSKLAPIM
Sbjct: 1   METYGYLQRESCFQGPHELYFKNLSKRNKQIMEKNGNNRKLRVCVATCNRADYSKLAPIM 60

Query: 61  FGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVG 120
           FGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVG
Sbjct: 61  FGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVG 120

Query: 121 LALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHA 180
           LALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHA
Sbjct: 121 LALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHA 180

Query: 181 ITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDV 240
           ITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDV
Sbjct: 181 ITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSIIRMWLGDDV 240

Query: 241 KSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKG 300
           KSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKG
Sbjct: 241 KSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKG 300

Query: 301 IEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGE 360
           IEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGE
Sbjct: 301 IEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGE 360

Query: 361 NVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCF 420
           NVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCF
Sbjct: 361 NVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCF 420

Query: 421 PPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLI 480
           PPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLI
Sbjct: 421 PPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLI 480

Query: 481 LQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLH 540
           LQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLH
Sbjct: 481 LQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLH 540

Query: 541 LPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGH 600
           LPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGH
Sbjct: 541 LPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGH 600

Query: 601 LVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQ 660
           LVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQ
Sbjct: 601 LVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQ 660

Query: 661 AAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALS 720
           AAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALS
Sbjct: 661 AAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALS 720

Query: 721 SVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY 753
           SVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY
Sbjct: 721 SVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY 753


>gi|4885285 UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine
           kinase isoform 2 [Homo sapiens]
          Length = 722

 Score = 1438 bits (3722), Expect = 0.0
 Identities = 722/722 (100%), Positives = 722/722 (100%)

Query: 32  MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRM 91
           MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRM
Sbjct: 1   MEKNGNNRKLRVCVATCNRADYSKLAPIMFGIKTEPEFFELDVVVLGSHLIDDYGNTYRM 60

Query: 92  IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA 151
           IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA
Sbjct: 61  IEQDDFDINTRLHTIVRGEDEAAMVESVGLALVKLPDVLNRLKPDIMIVHGDRFDALALA 120

Query: 152 TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL 211
           TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL
Sbjct: 121 TSAALMNIRILHIEGGEVSGTIDDSIRHAITKLAHYHVCCTRSAEQHLISMCEDHDRILL 180

Query: 212 AGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDAL 271
           AGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDAL
Sbjct: 181 AGCPSYDKLLSAKNKDYMSIIRMWLGDDVKSKDYIVALQHPVTTDIKHSIKMFELTLDAL 240

Query: 272 ISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN 331
           ISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN
Sbjct: 241 ISFNKRTLVLFPNIDAGSKEMVRVMRKKGIEHHPNFRAVKHVPFDQFIQLVAHAGCMIGN 300

Query: 332 SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKI 391
           SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKI
Sbjct: 301 SSCGVREVGAFGTPVINLGTRQIGRETGENVLHVRDADTQDKILQALHLQFGKQYPCSKI 360

Query: 392 YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLR 451
           YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLR
Sbjct: 361 YGDGNAVPRILKFLKSIDLQEPLQKKFCFPPVKENISQDIDHILETLSALAVDLGGTNLR 420

Query: 452 VAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNP 511
           VAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNP
Sbjct: 421 VAIVSMKGEIVKKYTQFNPKTYEERINLILQMCVEAAAEAVKLNCRILGVGISTGGRVNP 480

Query: 512 REGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTL 571
           REGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTL
Sbjct: 481 REGIVLHSTKLIQEWNSVDLRTPLSDTLHLPVWVDNDGNCAALAERKFGQGKGLENFVTL 540

Query: 572 ITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREA 631
           ITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREA
Sbjct: 541 ITGTGIGGGIIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREA 600

Query: 632 KKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTM 691
           KKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTM
Sbjct: 601 KKLHDEDLLLVEGMSVPKDEAVGALHLIQAAKLGNAKAQSILRTAGTALGLGVVNILHTM 660

Query: 692 NPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRR 751
           NPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRR
Sbjct: 661 NPSLVILSGVLASHYIHIVKDVIRQQALSSVQDVDVVVSDLVDPALLGAASMVLDYTTRR 720

Query: 752 IY 753
           IY
Sbjct: 721 IY 722


>gi|157671949 rearranged L-myc fusion [Homo sapiens]
          Length = 1914

 Score = 34.7 bits (78), Expect = 0.34
 Identities = 14/55 (25%), Positives = 26/55 (47%)

Query: 581 IIHQHELIHGSSFCAAELGHLVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLH 635
           ++  +E + G S    +   + V  DG   +CG  GC   Y +   +Q+  +K+H
Sbjct: 925 VLLSNEKVFGPSSLKEKCSSMAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVH 979


>gi|4501915 ADAM metallopeptidase domain 9 isoform 1 precursor [Homo
           sapiens]
          Length = 819

 Score = 33.9 bits (76), Expect = 0.57
 Identities = 35/109 (32%), Positives = 51/109 (46%), Gaps = 9/109 (8%)

Query: 556 ERKFGQGKGLENFVTLITGTGIGG-GIIHQHELIHGSSFCAAELGHLVVSL--DGPDCSC 612
           ++ FG   G+    T+ + +  GG  +  Q  +   +S  A ELGH +     DG DCSC
Sbjct: 306 KKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRDCSC 365

Query: 613 GSHGCI-EAYASGMALQREAKKLHDEDLLLVEG----MSVPK-DEAVGA 655
           G+  CI  + ASG            E L L +G    +++PK DEA  A
Sbjct: 366 GAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSA 414


>gi|148747437 Mob4B protein [Homo sapiens]
          Length = 216

 Score = 33.5 bits (75), Expect = 0.75
 Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 424 KENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQM 483
           K+NI +   H  E L      LG  NLR A++  +GE + ++   N   +  +IN++   
Sbjct: 16  KKNIPEG-SHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGT 74

Query: 484 CVEAAAEAVKLNCRILGVG 502
             E   EA   +C ++  G
Sbjct: 75  ITEFCTEA---SCPVMSAG 90


>gi|27735029 MOB1, Mps One Binder kinase activator-like 1A [Homo
           sapiens]
          Length = 216

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 4/79 (5%)

Query: 424 KENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLILQM 483
           K+NI +   H  E L      LG  NLR+A++  +GE + ++   N   +  +IN++   
Sbjct: 16  KKNIPEG-SHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGT 74

Query: 484 CVEAAAEAVKLNCRILGVG 502
             +   E    +C ++  G
Sbjct: 75  ITDFCTEE---SCPVMSAG 90


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,722,890
Number of Sequences: 37866
Number of extensions: 1140963
Number of successful extensions: 2381
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2377
Number of HSP's gapped (non-prelim): 6
length of query: 753
length of database: 18,247,518
effective HSP length: 110
effective length of query: 643
effective length of database: 14,082,258
effective search space: 9054891894
effective search space used: 9054891894
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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