Guide to the Human Genome
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Search of human proteins with 189083688

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189083688 exosome component 7 [Homo sapiens]
         (291 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189083688 exosome component 7 [Homo sapiens]                       581   e-166
gi|31415882 exosome component 8 [Homo sapiens]                        112   4e-25
gi|77812672 exosome component 9 isoform 1 [Homo sapiens]              104   1e-22
gi|77812670 exosome component 9 isoform 2 [Homo sapiens]              104   1e-22
gi|188528628 polyribonucleotide nucleotidyltransferase 1 [Homo s...    29   5.6  
gi|20149698 l(3)mbt-like 2 [Homo sapiens]                              28   7.3  
gi|9506689 exosome component 4 [Homo sapiens]                          28   7.3  

>gi|189083688 exosome component 7 [Homo sapiens]
          Length = 291

 Score =  581 bits (1498), Expect = e-166
 Identities = 291/291 (100%), Positives = 291/291 (100%)

Query: 1   MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60
           MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV
Sbjct: 1   MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60

Query: 61  GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120
           GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD
Sbjct: 61  GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120

Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180
           LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI
Sbjct: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180

Query: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 240
           ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR
Sbjct: 181 ELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACSLASLLVSVTSKGVVTCMR 240

Query: 241 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG 291
           KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG
Sbjct: 241 KVGKGSLDPESIFEMMETGKRVGKVLHASLQSVVHKEESLGPKRQKVGFLG 291


>gi|31415882 exosome component 8 [Homo sapiens]
          Length = 276

 Score =  112 bits (280), Expect = 4e-25
 Identities = 73/264 (27%), Positives = 125/264 (47%), Gaps = 10/264 (3%)

Query: 18  VQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGVKAEMGTPKLEKPNEG 77
           ++E+ R DGR   ++R   V    +S   GSA VKLG+T ++ GVKAE   P  + P++G
Sbjct: 18  LKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKG 77

Query: 78  YLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYV 137
           Y+   VD     +  F      +     +  +  +  N   +  + LCISP +  WVLY 
Sbjct: 78  YVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYC 137

Query: 138 DVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENV 197
           D++ L+  GN+ DA + A+ AAL N ++P V  + +E    ++ L    Y    L++   
Sbjct: 138 DLICLDYDGNILDACTFALLAALKNVQLPEV-TINEETALAEVNLKKKSY----LNIRTH 192

Query: 198 PCIVTLCKI-GYRHVVDATLQEEACSLASLLVSVTSKGVVTCMRKVGKGSLDPESIFEMM 256
           P   +         +VD T +EE  +  +L + +  +G + C+ K G   L    + + M
Sbjct: 193 PVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCM 252

Query: 257 ETG----KRVGKVLHASLQSVVHK 276
                  K V K++   ++S+  K
Sbjct: 253 SRAVTRHKEVKKLMDEVIKSMKPK 276


>gi|77812672 exosome component 9 isoform 1 [Homo sapiens]
          Length = 456

 Score =  104 bits (259), Expect = 1e-22
 Identities = 78/292 (26%), Positives = 137/292 (46%), Gaps = 11/292 (3%)

Query: 1   MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60
           M    LS  E+ +++  ++E  R+DGR   DYR + +         G   V+LG T +L 
Sbjct: 1   MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 57

Query: 61  GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120
            V  E+ +PKL +  EG L F ++ S  A P FE     DL  ++   + R   N   +D
Sbjct: 58  QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117

Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180
            ++LC+   E  W + VD+ LL   GN+ DA SIA   AL + R P V V    +G +  
Sbjct: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 173

Query: 181 ELSDDPYDCIRLSVENVPCIVTLC--KIGYRHVVDATLQEEACSLASLLVSVTSKGVVTC 238
             + +  D + LS+ ++P  V+    + G   +VD   +EE      L++++     +  
Sbjct: 174 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICT 233

Query: 239 MRKVGKGSLDPESIFEMME-TGKRVGKVLHASLQSVVHKEESLGPKRQKVGF 289
           ++  G   L  + +    +  G +V ++    L++ +  ++ +  +  K GF
Sbjct: 234 IQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKA-LENDQKVRKEGGKFGF 284


>gi|77812670 exosome component 9 isoform 2 [Homo sapiens]
          Length = 439

 Score =  104 bits (259), Expect = 1e-22
 Identities = 78/292 (26%), Positives = 137/292 (46%), Gaps = 11/292 (3%)

Query: 1   MASVTLSEAEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILV 60
           M    LS  E+ +++  ++E  R+DGR   DYR + +         G   V+LG T +L 
Sbjct: 1   MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRIS---FGTDYGCCIVELGKTRVLG 57

Query: 61  GVKAEMGTPKLEKPNEGYLEFFVDCSASATPEFEGRGGDDLGTEIANTLYRIFNNKSSVD 120
            V  E+ +PKL +  EG L F ++ S  A P FE     DL  ++   + R   N   +D
Sbjct: 58  QVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCID 117

Query: 121 LKTLCISPREHCWVLYVDVLLLECGGNLFDAISIAVKAALFNTRIPRVRVLEDEEGSKDI 180
            ++LC+   E  W + VD+ LL   GN+ DA SIA   AL + R P V V    +G +  
Sbjct: 118 TESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSV----QGDEVT 173

Query: 181 ELSDDPYDCIRLSVENVPCIVTLC--KIGYRHVVDATLQEEACSLASLLVSVTSKGVVTC 238
             + +  D + LS+ ++P  V+    + G   +VD   +EE      L++++     +  
Sbjct: 174 LYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICT 233

Query: 239 MRKVGKGSLDPESIFEMME-TGKRVGKVLHASLQSVVHKEESLGPKRQKVGF 289
           ++  G   L  + +    +  G +V ++    L++ +  ++ +  +  K GF
Sbjct: 234 IQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKA-LENDQKVRKEGGKFGF 284


>gi|188528628 polyribonucleotide nucleotidyltransferase 1 [Homo
           sapiens]
          Length = 783

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 18/54 (33%), Positives = 25/54 (46%)

Query: 9   AEKVYIVHGVQEDLRVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTDILVGV 62
           A++V+    + E  R DGR     R V  E D+     GSA  + G T +L  V
Sbjct: 344 AKEVFRSIVLNEYKRCDGRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTV 397


>gi|20149698 l(3)mbt-like 2 [Homo sapiens]
          Length = 705

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 164 RIPRVRVLEDEEGSKDIELSDDPYDCIRLSVENVPCIVTLCKIGYRHVVDATLQEEACS 222
           RIP  +     +GSK   L DDP    ++S E VP  +   ++   H +D    ++A S
Sbjct: 632 RIPPTKTRPLRQGSKKPLLEDDPQGARKISSEPVPGEIIAVRVKEEH-LDVASPDKASS 689


>gi|9506689 exosome component 4 [Homo sapiens]
          Length = 245

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 12/148 (8%)

Query: 23  RVDGRGCEDYRCVEVETDVVSNTSGSARVKLGHTD---ILVGVKAEMGTPKLEKPNEGYL 79
           RVDGR   + R ++    V +   GSA ++ G+T    ++ G     G+     P+   +
Sbjct: 13  RVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALV 72

Query: 80  EFFVDCSASATPEFEGR-GGDDLGTEIANTLYRIFNNKSSVDLKTLCISPREHCWVLYVD 138
                 +  +T E + R  GD    E+   L + F       L      PR     + + 
Sbjct: 73  NCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQL-----HPRSQ---IDIY 124

Query: 139 VLLLECGGNLFDAISIAVKAALFNTRIP 166
           V +L+  G  + A   A   A+ +  IP
Sbjct: 125 VQVLQADGGTYAACVNAATLAVLDAGIP 152


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,768,589
Number of Sequences: 37866
Number of extensions: 455281
Number of successful extensions: 994
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 984
Number of HSP's gapped (non-prelim): 7
length of query: 291
length of database: 18,247,518
effective HSP length: 101
effective length of query: 190
effective length of database: 14,423,052
effective search space: 2740379880
effective search space used: 2740379880
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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