Search of human proteins with 18644732

Search of human proteins with 18644732

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18644732 cystatin 11 isoform 2 precursor [Homo sapiens]
         (103 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18644732 cystatin 11 isoform 2 precursor [Homo sapiens]            212   4e-56
gi|19882249 cystatin 11 isoform 1 precursor [Homo sapiens]            194   1e-50
gi|18104940 cystatin 9-like precursor [Homo sapiens]                   41   2e-04
gi|4885163 cystatin 8 precursor [Homo sapiens]                         39   7e-04
gi|4503105 cystatin SA precursor [Homo sapiens]                        39   7e-04
gi|4503109 cystatin S precursor [Homo sapiens]                         37   0.004
gi|4503107 cystatin C precursor [Homo sapiens]                         36   0.006
gi|19882251 cystatin SN precursor [Homo sapiens]                       35   0.010
gi|19882259 cystatin-like 1 precursor [Homo sapiens]                   29   0.70 
gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...    29   0.91 
gi|194595509 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) ...    29   0.91 
gi|28610147 interleukin 6 signal transducer isoform 1 precursor ...    28   2.0  
gi|4503113 cystatin M precursor [Homo sapiens]                         27   2.6  
gi|19882256 cystatin D precursor [Homo sapiens]                        27   2.6  
gi|20302139 cystatin F [Homo sapiens]                                  26   7.7  
gi|75905803 parathyroid hormone-responsive B1 isoform 4 [Homo sa...    26   7.7  
gi|75905801 parathyroid hormone-responsive B1 isoform 3 [Homo sa...    26   7.7  
gi|38569434 parathyroid hormone-responsive B1 isoform 2 [Homo sa...    26   7.7  
gi|38569432 parathyroid hormone-responsive B1 isoform 1 [Homo sa...    26   7.7  

>gi|18644732 cystatin 11 isoform 2 precursor [Homo sapiens]
          Length = 103

 Score =  212 bits (540), Expect = 4e-56
 Identities = 103/103 (100%), Positives = 103/103 (100%)

Query: 1   MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESD 60
           MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESD
Sbjct: 1   MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESD 60

Query: 61  DKYHFRIFRVLKVQRQQVNCFFSVFAVPWFEQYKILNKSCSSD 103
           DKYHFRIFRVLKVQRQQVNCFFSVFAVPWFEQYKILNKSCSSD
Sbjct: 61  DKYHFRIFRVLKVQRQQVNCFFSVFAVPWFEQYKILNKSCSSD 103


>gi|19882249 cystatin 11 isoform 1 precursor [Homo sapiens]
          Length = 138

 Score =  194 bits (494), Expect = 1e-50
 Identities = 103/138 (74%), Positives = 103/138 (74%), Gaps = 35/138 (25%)

Query: 1   MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESD 60
           MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESD
Sbjct: 1   MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESD 60

Query: 61  DKYHFRIFRVLKVQRQ-----------------------------------QVNCFFSVF 85
           DKYHFRIFRVLKVQRQ                                   QVNCFFSVF
Sbjct: 61  DKYHFRIFRVLKVQRQVTDHLEYHLNVEMQWTTCQKPETTNCVPQERELHKQVNCFFSVF 120

Query: 86  AVPWFEQYKILNKSCSSD 103
           AVPWFEQYKILNKSCSSD
Sbjct: 121 AVPWFEQYKILNKSCSSD 138


>gi|18104940 cystatin 9-like precursor [Homo sapiens]
          Length = 147

 Score = 41.2 bits (95), Expect = 2e-04
 Identities = 32/144 (22%), Positives = 55/144 (38%), Gaps = 46/144 (31%)

Query: 1   MMAEPWQ-----ALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQY 55
           M+  PW+     AL LLL     L+   +   ++     H VMA   Y   ++++    +
Sbjct: 1   MLGLPWKGGLSWALLLLLLGSQILLIYAWHFHEQRDCDEHNVMA--RYLPATVEFAVHTF 58

Query: 56  NKESDDKYHFRIFRVLKVQRQQV------------------------------------- 78
           N++S D Y +R+  +L   ++QV                                     
Sbjct: 59  NQQSKDYYAYRLGHILNSWKEQVESKTVFSMELLLGRTRCGKFEDDIDNCHFQESTELNN 118

Query: 79  --NCFFSVFAVPWFEQYKILNKSC 100
              CFF++   PW  Q+ +LNK+C
Sbjct: 119 TFTCFFTISTRPWMTQFSLLNKTC 142


>gi|4885163 cystatin 8 precursor [Homo sapiens]
          Length = 142

 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 34/135 (25%), Positives = 52/135 (38%), Gaps = 41/135 (30%)

Query: 6   WQALQLLLAILLTLMALPYQARKKTFL--SVHEVMAVENYAKDSLQWITDQYNKESDDKY 63
           W +L +LL I L L+A     + +T +   +  V A     K  L +   +YNKES+DKY
Sbjct: 6   WLSL-ILLTIPLALVARKDPKKNETGVLRKLKPVNASNANVKQCLWFAMQEYNKESEDKY 64

Query: 64  HFRIFRVLKVQRQQVN--------------------------------------CFFSVF 85
            F + + L+ Q Q  N                                      C F V 
Sbjct: 65  VFLVVKTLQAQLQVTNLLEYLIDVEIARSDCRKPLSTNEICAIQENSKLKRKLSCSFLVG 124

Query: 86  AVPWFEQYKILNKSC 100
           A+PW  ++ ++ K C
Sbjct: 125 ALPWNGEFTVMEKKC 139


>gi|4503105 cystatin SA precursor [Homo sapiens]
          Length = 141

 Score = 39.3 bits (90), Expect = 7e-04
 Identities = 25/136 (18%), Positives = 54/136 (39%), Gaps = 41/136 (30%)

Query: 6   WQALQLLLAILLTLMALPYQARKKTFL---SVHEVMAVENYAKDSLQWITDQYNKESDDK 62
           W    LLL +    +AL +  +++  +    +++    +   + +L ++  +YNK ++D+
Sbjct: 3   WPLCTLLLLLATQAVALAWSPQEEDRIIEGGIYDADLNDERVQRALHFVISEYNKATEDE 62

Query: 63  YHFRIFRVLKVQRQQVN--------------------------------------CFFSV 84
           Y+ R+ RVL+ + Q V                                       C F +
Sbjct: 63  YYRRLLRVLRAREQIVGGVNYFFDIEVGRTICTKSQPNLDTCAFHEQPELQKKQLCSFQI 122

Query: 85  FAVPWFEQYKILNKSC 100
           + VPW ++  ++N  C
Sbjct: 123 YEVPWEDRMSLVNSRC 138


>gi|4503109 cystatin S precursor [Homo sapiens]
          Length = 141

 Score = 36.6 bits (83), Expect = 0.004
 Identities = 24/87 (27%), Positives = 44/87 (50%), Gaps = 4/87 (4%)

Query: 2  MAEPWQALQLLLAILLTLMALPYQARKKTFLS-VHEVMAVENYAKDSLQWITDQYNKESD 60
          MA P   L LL+A L   +A   +   +     +++    + + + +L +   +YNK ++
Sbjct: 1  MARPLCTLLLLMATLAGALASSSKEENRIIPGGIYDADLNDEWVQRALHFAISEYNKATE 60

Query: 61 DKYHFRIFRVLKVQRQQ---VNCFFSV 84
          D+Y+ R  +VL+ + Q    VN FF V
Sbjct: 61 DEYYRRPLQVLRAREQTFGGVNYFFDV 87


>gi|4503107 cystatin C precursor [Homo sapiens]
          Length = 146

 Score = 36.2 bits (82), Expect = 0.006
 Identities = 28/92 (30%), Positives = 43/92 (46%), Gaps = 9/92 (9%)

Query: 2  MAEPWQALQLLLAILLTLMALPYQARK------KTFLSVHEVMAVENYAKDSLQWITDQY 55
          MA P +A  LLLAIL   +A+   A        +      +    E   + +L +   +Y
Sbjct: 1  MAGPLRAPLLLLAILAVALAVSPAAGSSPGKPPRLVGGPMDASVEEEGVRRALDFAVGEY 60

Query: 56 NKESDDKYHFRIFRVLKVQRQ---QVNCFFSV 84
          NK S+D YH R  +V++ ++Q    VN F  V
Sbjct: 61 NKASNDMYHSRALQVVRARKQIVAGVNYFLDV 92


>gi|19882251 cystatin SN precursor [Homo sapiens]
          Length = 141

 Score = 35.4 bits (80), Expect = 0.010
 Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 7/85 (8%)

Query: 7  QALQLLLAILLTL-MALPYQARKKTFL---SVHEVMAVENYAKDSLQWITDQYNKESDDK 62
          Q L  LL +L TL +AL +  +++  +    ++     + + + +L +   +YNK + D 
Sbjct: 3  QYLSTLLLLLATLAVALAWSPKEEDRIIPGGIYNADLNDEWVQRALHFAISEYNKATKDD 62

Query: 63 YHFRIFRVLKVQRQQ---VNCFFSV 84
          Y+ R  RVL+ ++Q    VN FF V
Sbjct: 63 YYRRPLRVLRARQQTVGGVNYFFDV 87


>gi|19882259 cystatin-like 1 precursor [Homo sapiens]
          Length = 145

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 26/132 (19%), Positives = 50/132 (37%), Gaps = 40/132 (30%)

Query: 6   WQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHF 65
           W+   LLL  L+    L +  R + F    ++M+ +N    +L +    YN  S+D Y +
Sbjct: 6   WRNPLLLLIALVLSAKLGHFQRWEGFQQ--KLMSKKNM-NSTLNFFIQSYNNASNDTYLY 62

Query: 66  RIFRVLKVQ-------------------------------------RQQVNCFFSVFAVP 88
           R+ R+++ Q                                     R+ + C   ++ +P
Sbjct: 63  RVQRLIRSQMQLTTGVEYIVTVKIGWTKCKRNDTSNSSCPLQSKKLRKSLICESLIYTMP 122

Query: 89  WFEQYKILNKSC 100
           W   +++ N SC
Sbjct: 123 WINYFQLWNNSC 134


>gi|154759259 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
            isoform 2 [Homo sapiens]
          Length = 2472

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 12/86 (13%)

Query: 3    AEPWQALQLLLAILLTLMALPY------------QARKKTFLSVHEVMAVENYAKDSLQW 50
            A PW++ +L++  + T  ++              + R +   S HEV      A ++ +W
Sbjct: 1189 ASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEW 1248

Query: 51   ITDQYNKESDDKYHFRIFRVLKVQRQ 76
            I ++    + D Y   +  V  +QR+
Sbjct: 1249 IEEKNQALNTDNYGHDLASVQALQRK 1274


>gi|194595509 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
            isoform 1 [Homo sapiens]
          Length = 2477

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 12/86 (13%)

Query: 3    AEPWQALQLLLAILLTLMALPY------------QARKKTFLSVHEVMAVENYAKDSLQW 50
            A PW++ +L++  + T  ++              + R +   S HEV      A ++ +W
Sbjct: 1189 ASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEW 1248

Query: 51   ITDQYNKESDDKYHFRIFRVLKVQRQ 76
            I ++    + D Y   +  V  +QR+
Sbjct: 1249 IEEKNQALNTDNYGHDLASVQALQRK 1274


>gi|28610147 interleukin 6 signal transducer isoform 1 precursor
           [Homo sapiens]
          Length = 918

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 16/50 (32%), Positives = 26/50 (52%), Gaps = 7/50 (14%)

Query: 14  AILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKY 63
           A +LT+ A  +QA        H VM ++ + KD++ W+     +ES  KY
Sbjct: 411 AAVLTIPACDFQA-------THPVMDLKAFPKDNMLWVEWTTPRESVKKY 453


>gi|4503113 cystatin M precursor [Homo sapiens]
          Length = 149

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 9/27 (33%), Positives = 16/27 (59%)

Query: 74  QRQQVNCFFSVFAVPWFEQYKILNKSC 100
           Q++++ C F V  VPW    ++L  +C
Sbjct: 120 QQEKLRCDFEVLVVPWQNSSQLLKHNC 146



 Score = 26.9 bits (58), Expect = 3.5
 Identities = 18/71 (25%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 12 LLAILLTLMALPYQAR----KKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHFRI 67
          L  +   L+ALP  AR    ++    + ++   +   + + Q     YN  S+  Y+FR 
Sbjct: 12 LALVAFCLLALPRDARARPQERMVGELRDLSPDDPQVQKAAQAAVASYNMGSNSIYYFRD 71

Query: 68 FRVLKVQRQQV 78
            ++K Q Q V
Sbjct: 72 THIIKAQSQLV 82


>gi|19882256 cystatin D precursor [Homo sapiens]
          Length = 142

 Score = 27.3 bits (59), Expect = 2.6
 Identities = 29/139 (20%), Positives = 48/139 (34%), Gaps = 40/139 (28%)

Query: 2   MAEPWQALQLLLAILLTLMALPYQARKKTFLS-VHEVMAVENYAKDSLQWITDQYNKE-S 59
           M  P     LLL  L+  +A    A+ +T    +H     +   + +L +   +YNK  +
Sbjct: 1   MMWPMHTPLLLLTALMVAVAGSASAQSRTLAGGIHATDLNDKSVQCALDFAISEYNKVIN 60

Query: 60  DDKYHFRIFRVLKVQRQQVN--------------------------------------CF 81
            D+Y+ R  +V+   +Q V                                       C 
Sbjct: 61  KDEYYSRPLQVMAAYQQIVGGVNYYFNVKFGRTTCTKSQPNLDNCPFNDQPKLKEEEFCS 120

Query: 82  FSVFAVPWFEQYKILNKSC 100
           F +  VPW ++  ILN  C
Sbjct: 121 FQINEVPWEDKISILNYKC 139


>gi|20302139 cystatin F [Homo sapiens]
          Length = 167

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 7/28 (25%), Positives = 17/28 (60%)

Query: 68  FRVLKVQRQQVNCFFSVFAVPWFEQYKI 95
           F+     +Q ++C+  V+ VPW + +++
Sbjct: 134 FQTNHTLKQTLSCYSEVWVVPWLQHFEV 161


>gi|75905803 parathyroid hormone-responsive B1 isoform 4 [Homo
           sapiens]
          Length = 882

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/41 (29%), Positives = 21/41 (51%)

Query: 22  LPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDK 62
           L Y +R  +FL+V     VE+Y    L + TD   ++  ++
Sbjct: 184 LAYSSRTDSFLTVSSCQQVESYKYQVLAFATDADKRQETEQ 224


>gi|75905801 parathyroid hormone-responsive B1 isoform 3 [Homo
           sapiens]
          Length = 852

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/41 (29%), Positives = 21/41 (51%)

Query: 22  LPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDK 62
           L Y +R  +FL+V     VE+Y    L + TD   ++  ++
Sbjct: 184 LAYSSRTDSFLTVSSCQQVESYKYQVLAFATDADKRQETEQ 224


>gi|38569434 parathyroid hormone-responsive B1 isoform 2 [Homo
           sapiens]
          Length = 887

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/41 (29%), Positives = 21/41 (51%)

Query: 22  LPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDK 62
           L Y +R  +FL+V     VE+Y    L + TD   ++  ++
Sbjct: 184 LAYSSRTDSFLTVSSCQQVESYKYQVLAFATDADKRQETEQ 224


>gi|38569432 parathyroid hormone-responsive B1 isoform 1 [Homo
           sapiens]
          Length = 847

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 12/41 (29%), Positives = 21/41 (51%)

Query: 22  LPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDK 62
           L Y +R  +FL+V     VE+Y    L + TD   ++  ++
Sbjct: 184 LAYSSRTDSFLTVSSCQQVESYKYQVLAFATDADKRQETEQ 224


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.134    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,282,087
Number of Sequences: 37866
Number of extensions: 101805
Number of successful extensions: 328
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 299
Number of HSP's gapped (non-prelim): 28
length of query: 103
length of database: 18,247,518
effective HSP length: 74
effective length of query: 29
effective length of database: 15,445,434
effective search space: 447917586
effective search space used: 447917586
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.