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Search of human proteins with 18093112
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18093112 ABT1-associated protein [Homo sapiens]
(851 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18093112 ABT1-associated protein [Homo sapiens] 1687 0.0
gi|169173337 PREDICTED: similar to ABT1-associated protein [Homo... 176 1e-43
gi|169172536 PREDICTED: similar to ABT1-associated protein [Homo... 176 1e-43
gi|169173104 PREDICTED: similar to ABT1-associated protein [Homo... 176 1e-43
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 72 2e-12
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 72 2e-12
gi|148746195 trichohyalin [Homo sapiens] 68 4e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 65 2e-10
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 65 3e-10
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 65 3e-10
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 65 3e-10
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 64 6e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 64 6e-10
gi|24415404 MDN1, midasin homolog [Homo sapiens] 63 1e-09
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 62 2e-09
gi|115529449 upstream binding transcription factor, RNA polymera... 62 3e-09
gi|115529451 upstream binding transcription factor, RNA polymera... 62 3e-09
gi|7657671 upstream binding transcription factor, RNA polymerase... 62 3e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 61 4e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 61 4e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 61 4e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 61 4e-09
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 60 9e-09
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 60 9e-09
gi|71061468 centromere protein E [Homo sapiens] 60 9e-09
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 59 1e-08
gi|51477718 TATA box binding protein-associated factor, RNA poly... 59 1e-08
gi|34577114 cytomatrix protein p110 [Homo sapiens] 59 2e-08
gi|104526627 triadin [Homo sapiens] 59 2e-08
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 58 3e-08
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 1687 bits (4370), Expect = 0.0
Identities = 851/851 (100%), Positives = 851/851 (100%)
Query: 1 MSSKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPI 60
MSSKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPI
Sbjct: 1 MSSKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPI 60
Query: 61 SHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKA 120
SHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKA
Sbjct: 61 SHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKA 120
Query: 121 NHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSS 180
NHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSS
Sbjct: 121 NHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSS 180
Query: 181 LEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALE 240
LEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALE
Sbjct: 181 LEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALE 240
Query: 241 EDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGP 300
EDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGP
Sbjct: 241 EDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGP 300
Query: 301 DLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRL 360
DLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRL
Sbjct: 301 DLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRL 360
Query: 361 KAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSR 420
KAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSR
Sbjct: 361 KAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSR 420
Query: 421 EKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEP 480
EKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEP
Sbjct: 421 EKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEP 480
Query: 481 KDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYL 540
KDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYL
Sbjct: 481 KDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYL 540
Query: 541 ASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKEND 600
ASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKEND
Sbjct: 541 ASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKEND 600
Query: 601 MEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEE 660
MEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEE
Sbjct: 601 MEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEE 660
Query: 661 LPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSK 720
LPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSK
Sbjct: 661 LPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSK 720
Query: 721 KHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNF 780
KHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNF
Sbjct: 721 KHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNF 780
Query: 781 KKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTE 840
KKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTE
Sbjct: 781 KKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTE 840
Query: 841 QFQARKKQKVK 851
QFQARKKQKVK
Sbjct: 841 QFQARKKQKVK 851
>gi|169173337 PREDICTED: similar to ABT1-associated protein [Homo
sapiens]
Length = 101
Score = 176 bits (445), Expect = 1e-43
Identities = 87/99 (87%), Positives = 91/99 (91%)
Query: 1 MSSKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPI 60
MSSKQEIMSDQ FR+VAKDPRFWEMPE+DRKVKI +R RAMFHDKKFKLNYAVDKRGRP
Sbjct: 1 MSSKQEIMSDQLFRQVAKDPRFWEMPEEDRKVKIHRRCRAMFHDKKFKLNYAVDKRGRPN 60
Query: 61 SHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKT 99
+HSTTEDLK FYDLSDSDSNLS EDSKAL QKKIKK KT
Sbjct: 61 NHSTTEDLKHFYDLSDSDSNLSNEDSKALKQKKIKKIKT 99
>gi|169172536 PREDICTED: similar to ABT1-associated protein [Homo
sapiens]
Length = 101
Score = 176 bits (445), Expect = 1e-43
Identities = 87/99 (87%), Positives = 91/99 (91%)
Query: 1 MSSKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPI 60
MSSKQEIMSDQ FR+VAKDPRFWEMPE+DRKVKI +R RAMFHDKKFKLNYAVDKRGRP
Sbjct: 1 MSSKQEIMSDQLFRQVAKDPRFWEMPEEDRKVKIHRRCRAMFHDKKFKLNYAVDKRGRPN 60
Query: 61 SHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKT 99
+HSTTEDLK FYDLSDSDSNLS EDSKAL QKKIKK KT
Sbjct: 61 NHSTTEDLKHFYDLSDSDSNLSNEDSKALKQKKIKKIKT 99
>gi|169173104 PREDICTED: similar to ABT1-associated protein [Homo
sapiens]
Length = 101
Score = 176 bits (445), Expect = 1e-43
Identities = 87/99 (87%), Positives = 91/99 (91%)
Query: 1 MSSKQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPI 60
MSSKQEIMSDQ FR+VAKDPRFWEMPE+DRKVKI +R RAMFHDKKFKLNYAVDKRGRP
Sbjct: 1 MSSKQEIMSDQLFRQVAKDPRFWEMPEEDRKVKIHRRCRAMFHDKKFKLNYAVDKRGRPN 60
Query: 61 SHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKT 99
+HSTTEDLK FYDLSDSDSNLS EDSKAL QKKIKK KT
Sbjct: 61 NHSTTEDLKHFYDLSDSDSNLSNEDSKALKQKKIKKIKT 99
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 72.4 bits (176), Expect = 2e-12
Identities = 69/302 (22%), Positives = 132/302 (43%), Gaps = 31/302 (10%)
Query: 73 DLSDSDSNLSGEDSKALSQKKIKKKKTQTKKE---IDSKNLVEKKKETKKANHKG----- 124
+L + +S + K +K + + T TK++ + S+ LV K + +N+K
Sbjct: 29 ELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTK 88
Query: 125 SENKTDLDN-----SIGIKKMKTSCKFKIDSNIS--PKKDSKEFTQKNKKEKKNIVQHTT 177
++ T+ N S K++ K ++ S+ S P K+ E T K++ + + T
Sbjct: 89 GKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPT 148
Query: 178 DSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKD 237
E +D S +S + E + E S + + SD N+T+ E ++
Sbjct: 149 PDGSERIGLEVDRRASRSSQSSKEEVNS--EEYGSDHETGSSGSSDEQGNNTENE---EE 203
Query: 238 ALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSD 297
+EED E E+ D E + E+ G+++ E++EEE+E+EEE+E+ + ++ D+ +
Sbjct: 204 GVEEDVEEDEEVEEDAEEDEEVDE----DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
Query: 298 SGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDW 357
G D +T SE D ++ G + D + E R + + +
Sbjct: 260 EGND-------YDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVF 312
Query: 358 DR 359
DR
Sbjct: 313 DR 314
Score = 38.9 bits (89), Expect = 0.020
Identities = 26/102 (25%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Query: 545 EDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
E++EE+EE+ + D+ V+EDG+ ++ ++++EE+ + + E+++K + ND +
Sbjct: 210 EEDEEVEEDAEEDE--EVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTR 267
Query: 605 IKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLK 646
+ +S E V + + EKKKE+KR +
Sbjct: 268 SE----ASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRAR 305
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 72.4 bits (176), Expect = 2e-12
Identities = 69/302 (22%), Positives = 132/302 (43%), Gaps = 31/302 (10%)
Query: 73 DLSDSDSNLSGEDSKALSQKKIKKKKTQTKKE---IDSKNLVEKKKETKKANHKG----- 124
+L + +S + K +K + + T TK++ + S+ LV K + +N+K
Sbjct: 29 ELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTK 88
Query: 125 SENKTDLDN-----SIGIKKMKTSCKFKIDSNIS--PKKDSKEFTQKNKKEKKNIVQHTT 177
++ T+ N S K++ K ++ S+ S P K+ E T K++ + + T
Sbjct: 89 GKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPT 148
Query: 178 DSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKD 237
E +D S +S + E + E S + + SD N+T+ E ++
Sbjct: 149 PDGSERIGLEVDRRASRSSQSSKEEVNS--EEYGSDHETGSSGSSDEQGNNTENE---EE 203
Query: 238 ALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSD 297
+EED E E+ D E + E+ G+++ E++EEE+E+EEE+E+ + ++ D+ +
Sbjct: 204 GVEEDVEEDEEVEEDAEEDEEVDE----DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKE 259
Query: 298 SGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDW 357
G D +T SE D ++ G + D + E R + + +
Sbjct: 260 EGND-------YDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRARGISPIVF 312
Query: 358 DR 359
DR
Sbjct: 313 DR 314
Score = 38.9 bits (89), Expect = 0.020
Identities = 26/102 (25%), Positives = 54/102 (52%), Gaps = 6/102 (5%)
Query: 545 EDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
E++EE+EE+ + D+ V+EDG+ ++ ++++EE+ + + E+++K + ND +
Sbjct: 210 EEDEEVEEDAEEDE--EVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTR 267
Query: 605 IKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLK 646
+ +S E V + + EKKKE+KR +
Sbjct: 268 SE----ASDSGSESVSFTDGSVRSGSGTDGSDEKKKERKRAR 305
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 67.8 bits (164), Expect = 4e-11
Identities = 145/822 (17%), Positives = 334/822 (40%), Gaps = 113/822 (13%)
Query: 69 KRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKN----LVEK---KKETKKAN 121
+R L + + L + + SQ++ + +K + + E + K L K +++ +K
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Query: 122 HKGSENKTDLDNSIGIKKMKTSCK--FKIDSNISPKKDS--KEFTQKNKKEKKNIVQHTT 177
E + +L K+ + + ++ + + +++ +E +K +++++ Q+
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERER-QYRK 962
Query: 178 DSSLEEKQRTLDSGTSEIVKSPRIECSKTRRE----MQSVVQLIMTRDSDGYENSTDGEM 233
D L++K+ L E K R E K RE Q QL+ + +
Sbjct: 963 DKKLQQKEEQLLGEEPE--KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 234 CDKDALEEDSESVSEIGSD----EESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDED 289
KD L+++ E + + +E E + +++ +E E +E E +
Sbjct: 1021 RKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQY 1080
Query: 290 SEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRR 349
++++ L R + E E + + E RE +++ R E+ R+
Sbjct: 1081 RKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE-EREKRRRQELERQ 1139
Query: 350 LAVCNMDWDRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIP 409
+ + ++ ++ L +P+ K E ++ +EE++Q E L
Sbjct: 1140 YR----EEEEVQQEEEQLLRE--EPE-------KRRRQELERQYREEEELQQEEEQLLRE 1186
Query: 410 EDAPEKDWTSREKLRDYQFKRLKYYYAVVDCDS---------PETASKIYED---CDGLE 457
E + R+ + + +R K D D PE + + ++ C G E
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 458 FESSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHE 517
E F L D + +D S+ +L +G E +
Sbjct: 1247 NEQ---FRQLE--------DSQLRDRQSQQDL---------QHLLGEQQERDR--EQERR 1284
Query: 518 RITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEE 577
R +R F +EE L+ + Q +E ++ L+ E+ + K+ +++ +
Sbjct: 1285 RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR--------EEREEKRRRQETDR 1336
Query: 578 QIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLE 637
+ + QLLQ +E+ + +E D ++ EE ++++ +G+ L ++
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERD-----------RKFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 638 KKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEE 697
+++E+K LK +Q+ +E E++L D D F EE +Q+ + +D EE
Sbjct: 1386 QERERKFLKEEQQLRCQE-REQQLRQD---RDRKFREEEQQLS------RQERDRKFREE 1435
Query: 698 EIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKE----LIEDDF 753
E ++ RQ+ E L E+E + + K E + L +++++Q + ++E +E++
Sbjct: 1436 EQQVRRQERERKFL---EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 754 EVNVNDARFQAMYTSHLFNLDP------SDPNFKKTKAMEKILEEKARQRERKEQELTQA 807
++ R + L + +P + + + K L+E+ + R ++ + +
Sbjct: 1493 QLR-RQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
Query: 808 IKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQK 849
+ ++ E++ +++ + LS + K + E+ + R++++
Sbjct: 1552 DRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Score = 63.9 bits (154), Expect = 6e-10
Identities = 148/887 (16%), Positives = 369/887 (41%), Gaps = 108/887 (12%)
Query: 24 EMPEKDRKVKIDKRFRA---MFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDLSDSDSN 80
E PEK R+ + +K++R + +++ L +KR R ++ +R Y D
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR-------QEWERQYRKKDE--- 1025
Query: 81 LSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNSIGIKKM 140
L E+ + L +++ K++ + +++ + +++++E + + + +L+ K+
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR-KEE 1084
Query: 141 KTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPR 200
+ + + P+K ++ ++ +E++ + Q EE++ K R
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREERE-----------KRRR 1133
Query: 201 IECSKTRREMQSVVQ----LIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSD---- 252
E + RE + V Q L+ + + +++ L+++ E + +
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 253 -------EESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARG 305
EE E + + D+D D + + E E+E+ D++ K +
Sbjct: 1194 ERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQL 1253
Query: 306 KGNIETSSEDEDDTADLFPEESGFEHA-----WRELDKDAPRADEITRRLAVCNMDWDRL 360
+ + + + D L E+ + W++ D+ P +++ R DR
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR- 1312
Query: 361 KAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAP----EKD 416
K+++ L + + K E ++ +EEQ LL E+ P E+D
Sbjct: 1313 KSQEEKQLLREEREE-------KRRRQETDRKFREEEQ------LLQEREEQPLRRQERD 1359
Query: 417 WTSREKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPD-DIT 475
RE+ +Q + K+ E K ++ E + C + + D D
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKE----EQQLRCQEREQQLRQDRDRK 1415
Query: 476 FDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEE-LLDM 534
F +E + ++ + ++ + + E + E + + +RKF++EE LL
Sbjct: 1416 FREEEQQLSRQERDRKFREE---EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472
Query: 535 DFQAYLASSSEDEEEIEEELQ----GDDGVNVEEDGKTKKSQK---DDEEQIAKYRQLLQ 587
+ L D + +EEE Q D E++ ++++ ++ ++E+Q+ + ++ +
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Query: 588 VIQEKEK-------KGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKK 640
+QE+++ + + D + + + L++ EE ++ E K EQ + +++
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Query: 641 EKKRLKRKQKALAEEASEEELPSDVDLN---DPYFAEEVKQIGINKKSVKSAKDGTSPEE 697
++++ ++ L + +++L + D D +E ++ ++++ +D EE
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQE----RDRKFLEE 1648
Query: 698 EIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKE---------- 747
E ++ RQ+ E L D D ++ + E Q L ++++ + +++E
Sbjct: 1649 EPQLRRQEREQQL-RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 748 -LIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQ 806
++++ ++ + + L + ++ + KILEE+ + ER+EQ+L +
Sbjct: 1708 KFLQEEQQLRRQELERKFREEEQL-RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766
Query: 807 AIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQ--FQARKKQKVK 851
+ ++ E++ +++ + L K + E+ Q R++Q+++
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLR 1813
Score = 60.8 bits (146), Expect = 5e-09
Identities = 71/336 (21%), Positives = 157/336 (46%), Gaps = 53/336 (15%)
Query: 523 NRKFKKEELLDMDFQAYLASSSEDEEEIEEE------LQGDDGVNVEEDGKTKKSQKD-- 574
+RKF+++EL + + E+E+++ + LQ + + +E G+ ++ +D
Sbjct: 1500 DRKFREQELRSQEPERKFL---EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556
Query: 575 --DEEQIAKYRQLLQVI-QEKEKK-----GKENDMEMEIKWVPGLKESAEEMVKNKL--E 624
+EEQ+ + R+ Q+ QE+++K K E E K++ ++ + + +L E
Sbjct: 1557 FREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQE 1616
Query: 625 GKDKLTPWEQFLEKKKEKK--RLKRKQKALAEEAS------EEELPSDVDLNDPYFAEEV 676
K EQ L++++E++ R +R +K L EE E++L D D F EE
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD---RDRKFREEE 1673
Query: 677 K--QIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNL 734
+ Q G ++ + +D EEE ++ RQ+ E L E++ ++ K E + L
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ--EEQQLRRQELERKFREEEQL 1731
Query: 735 SKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKA 794
++ +++ ++++E R++ + + + ++ + K EE+
Sbjct: 1732 RQETEQEQLRRQE-------------RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQ 1778
Query: 795 RQRERKEQELTQAIK----KKESEIEKESQRKSIDP 826
++ER+EQ+L ++E ++ +E + + + P
Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRP 1814
Score = 53.1 bits (126), Expect = 1e-06
Identities = 52/304 (17%), Positives = 142/304 (46%), Gaps = 23/304 (7%)
Query: 527 KKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLL 586
++E+L ++ Q L ++EE+ ++ L+ + + +++ + ++ Q++ EQ + Q
Sbjct: 274 EEEQLRKLERQE-LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 587 QVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKR-- 644
+ +++ ++ +E E +++ +E EE + +L + + EQ L ++++ +R
Sbjct: 333 ERREQQLRREQEERREQQLR-----REQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 645 -LKRKQKALAEEA--SEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEI 701
L+R+Q+ E+ E++L + L +Q+ ++ + + E +
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 702 ERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDAR 761
+R++ E + E+E + H+ +K++ + +++E E ++ + R
Sbjct: 448 KREQEERRDWLKREEETER----------HEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Query: 762 FQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQR 821
Q + + ++ K E+ EE+ +QR R EQ+L + +++ ++ K +
Sbjct: 498 EQQERREQQLRREQEERREQRLKRQEE--EERLQQRLRSEQQLRREQEERREQLLKREEE 555
Query: 822 KSID 825
K ++
Sbjct: 556 KRLE 559
Score = 52.4 bits (124), Expect = 2e-06
Identities = 57/341 (16%), Positives = 157/341 (46%), Gaps = 25/341 (7%)
Query: 524 RKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKY- 582
R+ K+++ + + + ++ + E L+ ++ EE+ + ++ +++EEQ+ K
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 583 -RQLLQVIQEKEKKGK--ENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKK 639
++L + QE+E++ + + ++ K +E EE + + + + EQ L ++
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 640 KEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEI 699
+E++R ++ ++ EE E++L + + EE ++ + ++ + E+++
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQE-------EERREQQLRREQQLRREQQLRREQQL 395
Query: 700 EIERQKAEMALLMMDED---------EDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIE 750
E+Q L ++ E + + E ++ ++++++L +++E
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Query: 751 DDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKK 810
D + R + D + ++ +E+ EE+ Q+ER+EQ+L ++
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEE--EERREQQERREQQLR---RE 510
Query: 811 KESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQKVK 851
+E E+ +R+ + L ++S + + + R++Q +K
Sbjct: 511 QEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Score = 50.8 bits (120), Expect = 5e-06
Identities = 61/304 (20%), Positives = 137/304 (45%), Gaps = 30/304 (9%)
Query: 523 NRKFKKEE-LLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAK 581
+RKF+++E LL + L D + +EEE Q + + ++ + D + + +
Sbjct: 1618 DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQ------LRRQEREQQLRHDRDRKFRE 1671
Query: 582 YRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKE 641
QLLQ +E++ + +E D + EE + E + K EQ L +++E
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFR----------EEEQQLRRQERERKFLQEEQQL-RRQE 1720
Query: 642 KKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEI 701
+R R+++ L +E +E+L E+++ ++ + +D EEE ++
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE-QL 1779
Query: 702 ERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKK--KQLMKKKELIEDDFEVNVND 759
+++ E L + D ++ + E Q L +++ K ++++L ++ E +
Sbjct: 1780 RQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839
Query: 760 ARFQAMYTSHLFNLDPSDPNFKKTKAMEKIL---EEKARQRERKEQELTQAIKKKESEIE 816
R + F +K++ E+ L EE+ R++ER+ + + I++++ E +
Sbjct: 1840 ERDRQYRAEEQFATQ------EKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQ 1893
Query: 817 KESQ 820
+ Q
Sbjct: 1894 RHRQ 1897
Score = 50.4 bits (119), Expect = 7e-06
Identities = 56/305 (18%), Positives = 144/305 (47%), Gaps = 25/305 (8%)
Query: 545 EDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
E EE +E+ L+ ++ +E++ + ++ K +E + + +QLL+ +++E++ ++ E +
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 605 IKWVPGLK-ESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPS 663
+ LK E EE ++ +L+ + + EQ L ++++++ +R + + + + E +
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712
Query: 664 DVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHF 723
D + Y + KQ G ++ + K E E++ Q+ E A E+E ++ F
Sbjct: 713 DARQSKVY-SRPRKQEGQRRRQEQEEK---RRRRESELQWQEEERAHRQQQEEEQ-RRDF 767
Query: 724 NYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKT 783
+ E + S++ +++L + L E + R Q ++
Sbjct: 768 TWQWQAEEK--SERGRQRLSARPPLREQRERQLRAEERQQ-----------------REQ 808
Query: 784 KAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQ 843
+ + + E++ R+R+R+E+E ++E ++++ + + + L + + + Q Q
Sbjct: 809 RFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQ 868
Query: 844 ARKKQ 848
R ++
Sbjct: 869 RRDQK 873
Score = 48.5 bits (114), Expect = 3e-05
Identities = 59/364 (16%), Positives = 161/364 (44%), Gaps = 30/364 (8%)
Query: 517 ERITMLNRKFKKEELL-----DMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKS 571
E + L ++ ++E+ L + + + L S E EE +++L+ + E+ K ++
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Query: 572 QKDDEEQIAKY----RQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKD 627
++ E+++ + R+ ++ +E++++ +E KW L+ A+ ++K+ +
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR-QSKVYSRP 723
Query: 628 KLTPWEQFLEKKKEKKRLKRKQKALAEEA----SEEELPSDVDLNDPYFAEEVKQIGINK 683
+ ++ ++++EK+R + + EE ++E D + AEE + G +
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783
Query: 684 KSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLM 743
S + + ERQ+ E L +E+++ ++ + E Q L ++++ Q
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843
Query: 744 KKKELI---EDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAM-------------E 787
++ + + ED + + R Q + + ++ + +
Sbjct: 844 ERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQ 903
Query: 788 KILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARKK 847
++L+E+ + +R+E+E + +++ E+E ++ + L + + + + Q RK
Sbjct: 904 QLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Query: 848 QKVK 851
+K++
Sbjct: 964 KKLQ 967
Score = 45.4 bits (106), Expect = 2e-04
Identities = 61/358 (17%), Positives = 147/358 (41%), Gaps = 28/358 (7%)
Query: 517 ERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDE 576
ER+ ++ + E L + + E EEE ++L + + ++ Q++
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 577 EQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKL------------- 623
EQ K + + ++++ K+ E + E + +E A E +K+++
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEE-RREQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Query: 624 -EGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEEL--------PSDVDLNDPYFAE 674
+ K P +Q +++++++ KR+++ + EEE D + AE
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAE 774
Query: 675 EVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNL 734
E + G + S + + ERQ+ E L +E+++ ++ + E Q L
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFL 834
Query: 735 SKKKKKQLMKKKELI---EDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILE 791
++++ Q ++ + + ED + + R Q + + +K + +
Sbjct: 835 EEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEE--RKRRRHTLYAK 892
Query: 792 EKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQK 849
+++ RKEQ+L Q +++ E+E +R+ + ++ + EQ +++K
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK 950
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/279 (20%), Positives = 133/279 (47%), Gaps = 37/279 (13%)
Query: 545 EDEEEIEEELQGDDGVNVE-EDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEM 603
E+EE +++ L+ + + E E+ + + ++++E+++ + R+ ++ +E+E++ +
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKRE 582
Query: 604 EIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPS 663
E + LK EE ++ +L+ ++ E+ ++++ ++RLKR++ EE ++ L S
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEV----ERLEQEERREQRLKREEP--EEERRQQLLKS 636
Query: 664 DVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHF 723
+ EE +Q + ++ + + EE E ++ E L E+E ++
Sbjct: 637 EEQ-------EERRQQQLRREQQERREQRLKREE----EEERLEQRLKREHEEERREQEL 685
Query: 724 NYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKT 783
E + ++ K ++ K + +E + DAR +Y S P ++
Sbjct: 686 AEE---EQEQARERIKSRIPKWQWQLESE-----ADARQSKVY---------SRPRKQEG 728
Query: 784 KAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRK 822
+ + EEK R+RE + Q Q ++ + ++E QR+
Sbjct: 729 QRRRQEQEEKRRRRESELQ--WQEEERAHRQQQEEEQRR 765
Score = 45.1 bits (105), Expect = 3e-04
Identities = 57/323 (17%), Positives = 152/323 (47%), Gaps = 31/323 (9%)
Query: 527 KKEELLDMDFQAYLASSSEDEE-EIEEELQGDDGVNVEEDGKTKKSQKDDEEQIA---KY 582
++E+LL + + L ++ + E+E + D + EE+ + ++ +++ EE++ K
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 583 RQLLQVIQE--KEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKK 640
++ ++ QE +E++ K + E E + E EE + +L +++ EQ L++++
Sbjct: 605 EEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLR-REQQERREQRLKREE 663
Query: 641 EKKRLKRKQKAL-AEEASEEELPSD--------VDLNDPYFAEEVKQIGINKKSVKSAK- 690
E++RL+++ K EE E+EL + + P + +++ ++S ++
Sbjct: 664 EEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRP 723
Query: 691 ---DGTSPEEEIEIERQKAEMALLMMDE--------DEDSKKHFNYNKIVEHQNLSKKKK 739
+G +E E +R++ E L +E +E+ ++ F + E ++ ++
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS---ERG 780
Query: 740 KQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRER 799
+Q + + + + E + Q L + + ++ + EK L+ + +
Sbjct: 781 RQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL 840
Query: 800 KEQELTQAIKKKESEIEKESQRK 822
+ +E Q ++++E ++++ +R+
Sbjct: 841 QRRERAQQLQEEEDGLQEDQERR 863
Score = 42.7 bits (99), Expect = 0.001
Identities = 62/323 (19%), Positives = 136/323 (42%), Gaps = 48/323 (14%)
Query: 508 EITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSED-----------EEEIEEELQG 556
E+ W E + ++ ++E+ D +Q SE E+ E +L+
Sbjct: 745 ELQWQEEERAH----RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA 800
Query: 557 DDGVNVEEDGKTKKSQKDDEEQIAKYRQL-LQVIQEKEKKGKENDMEMEIKWVPGLKESA 615
++ E+ ++ +K+ + + R+ LQ ++E+E+ + + + GL+E
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Query: 616 EEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEE 675
E +++ + +D+ W+ E+K +R+ A+ A +E+L + L EE
Sbjct: 861 ERR-RSQEQRRDQKWRWQLEEERK------RRRHTLYAKPALQEQLRKEQQL----LQEE 909
Query: 676 VKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLS 735
+++ ++ + + E ERQ E L +E++ ++ + E +
Sbjct: 910 EEELQREEREKRRRQ---------EQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Query: 736 KKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKAR 795
+K KK K+++L+ ++ E R + + + E++L E+
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE-----------ELQQEEEQLLREERE 1009
Query: 796 QRERKEQELTQAIKKKESEIEKE 818
+R R+E E Q KK E + E+E
Sbjct: 1010 KRRRQEWE-RQYRKKDELQQEEE 1031
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/319 (18%), Positives = 147/319 (46%), Gaps = 45/319 (14%)
Query: 547 EEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGK--ENDMEME 604
+EE + + D EE G+ ++ ++ ++E R+L + ++ EK+ + + D +
Sbjct: 115 QEEDQRRFEPRDRQLEEEPGQRRRQKRQEQE-----RELAEGEEQSEKQERLEQRDRQRR 169
Query: 605 IKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKA-LAEEASEEELPS 663
+ + ++ +E + + E + + E+ ++++L+R++ L + EE+
Sbjct: 170 DEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 664 DVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKK-- 721
+ D F EE ++ +++V ++ EEE + +R+ + +E+E +K
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE-------LQEEEEQLRKLE 282
Query: 722 --HFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPN 779
+ E Q + +++Q +++K+ E++ + R Q
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQ--EEERREQQEERREQQ--------------- 325
Query: 780 FKKTKAMEKILEEKAR--QRERKEQEL--TQAIKKKESEIEKESQRKSIDPAL---SMLI 832
++ + E+ E++ R Q ER+EQ+L Q +++E ++ +E + + + L L
Sbjct: 326 -ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384
Query: 833 KSIKTKTEQFQARKKQKVK 851
+ + + EQ Q R++Q+++
Sbjct: 385 REQQLRREQ-QLRREQQLR 402
Score = 36.6 bits (83), Expect = 0.10
Identities = 39/187 (20%), Positives = 87/187 (46%), Gaps = 6/187 (3%)
Query: 522 LNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAK 581
L RKF++EE L + + E +I EE Q ++ + ++ +K EE+
Sbjct: 1721 LERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE--- 1777
Query: 582 YRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKE 641
QL Q +E++ + +E+D + + + +++ + +GK + + LE++++
Sbjct: 1778 --QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835
Query: 642 KKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEI 701
+ R +R ++ AEE + S + + + EE K+ ++ ++ +EE +
Sbjct: 1836 RLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEE-QR 1894
Query: 702 ERQKAEM 708
RQ E+
Sbjct: 1895 HRQVGEI 1901
Score = 30.4 bits (67), Expect = 7.3
Identities = 48/293 (16%), Positives = 117/293 (39%), Gaps = 39/293 (13%)
Query: 4 KQEIMSDQRFRRVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHS 63
+QE +QR +R E PE++R+ ++ K ++ ++R + +
Sbjct: 611 EQEERREQRLKR--------EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE 662
Query: 64 TTED-----LKRFYDLSDSDSNLSGEDSKALSQK---KIKKKKTQTKKEIDSKNLVEKKK 115
E+ LKR ++ + L+ E+ + ++ +I K + Q + E D++ + K
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR---QSKV 719
Query: 116 ETKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQH 175
++ +G + + + + + +S + +++ + Q+ ++E++
Sbjct: 720 YSRPRKQEGQRRRQEQEEK----------RRRRESELQWQEEERAHRQQQEEEQRR--DF 767
Query: 176 TTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCD 235
T EEK + G + P + + +RE Q + R+ + E
Sbjct: 768 TWQWQAEEKS---ERGRQRLSARPPL---REQRERQLRAEERQQREQRFLPEEEEKEQRR 821
Query: 236 KDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDE 288
+ E + E + +EE + ++DG ++D+E +E+ D+
Sbjct: 822 RQRREREKEL--QFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 65.5 bits (158), Expect = 2e-10
Identities = 93/440 (21%), Positives = 183/440 (41%), Gaps = 72/440 (16%)
Query: 392 ERMKEEQVQGPVELLSIPE-----DAPEKDWTSREKLRDYQFKRLKYYYAVVDCDSPETA 446
ER KE LS+P D E + T +E+ + + +R + + ET
Sbjct: 116 ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY-------EIEETETV 168
Query: 447 SKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYKPKYFTSAAMGTST 506
+K Y+ D + E + +D+ K+ E KPK ++G +
Sbjct: 169 TKSYQKNDWRDAEENKK-------------EDKEKEEEEEE-----KPK---RGSIGENQ 207
Query: 507 VEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDG 566
VE+ +E E +EE + M + SS E ++E E E QG D ++ E
Sbjct: 208 VEVMVEEKTTE---------SQEETVVMSLKNGQISSEEPKQEEERE-QGSDEISHHEKM 257
Query: 567 KTKKSQKDDEEQI---AKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKL 623
+ + ++ + E+ A+ R+ ++ Q+K+ + +E E K +E E + ++
Sbjct: 258 EEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERM 317
Query: 624 EGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINK 683
++K E+ K++EK+ + +Q+ EE E + + AEE ++ +
Sbjct: 318 REEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEE 377
Query: 684 KSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLM 743
EE+ ++E QK L + KKH ++ + + +K + + +
Sbjct: 378 ------------EEKAKVEEQKRNKQL-------EEKKHAMQETKIKGEKVEQKIEGKWV 418
Query: 744 KKKELIEDDFEVNVNDARFQAMYT---SHLFNLDPSDPNFKKTKAMEKILEEKARQRERK 800
+K+ ED + V + + T + L P FKK E+I +EK ++ +
Sbjct: 419 NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKK----EEIKDEKIKKDKEP 474
Query: 801 EQELTQAIKKKESEIEKESQ 820
++E+ + +K+ E +SQ
Sbjct: 475 KEEVKSFMDRKKGFTEVKSQ 494
Score = 53.5 bits (127), Expect = 8e-07
Identities = 133/702 (18%), Positives = 275/702 (39%), Gaps = 119/702 (16%)
Query: 72 YDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSEN-KTD 130
Y +D D E++ +++ ++++ + K+E +S V + E N E KT
Sbjct: 27 YQRNDDDE----EEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTT 82
Query: 131 LDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHT-TDSSLEEKQRTLD 189
N+ +++ + ++ +++ ++ + E++ T TD+SL R +
Sbjct: 83 TTNT----QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQ 138
Query: 190 SGTSEIVKSPRIECSKTRREMQSVVQ---LIMTRDSDGYENSTDGEMCDKDALEEDSES- 245
+ T+E + + E S++R+E + + + + + + ++ + + DK+ EE+ E
Sbjct: 139 NDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP 198
Query: 246 -------------VSEIGSDEESENEITSV--GRASGDDDGSEDDEEEDEDE----EEDE 286
V E ++ + E + S+ G+ S ++ E++ E+ DE E+ E
Sbjct: 199 KRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKME 258
Query: 287 DEDSEDDD--------------KSDSGPDLARGKGNIETSSE---------DEDDTADLF 323
+ED E + K++ +A + IE + + ++ +
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMR 318
Query: 324 PEESGFEHAWRELDKDAPRADEITRRLAV----CNMDWDRLKAKDLLALFNSFKPKGGVI 379
EE + + ++ RA E +R+ + R+K ++ A + +
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378
Query: 380 FSVKIYPSEFGKE------RMKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQFKRLKY 433
K+ + K+ M+E +++G E E W + +K ++ + +
Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQETKIKGEKV-----EQKIEGKWVNEKKAQEDKLQT--- 430
Query: 434 YYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYK 493
AV+ E +K+ + L+ E +F + I D EPK+ EV +
Sbjct: 431 --AVLKKQGEEKGTKVQAKREKLQ-EDKPTFKKEEIKDEKIKKDKEPKE---EVKSFMDR 484
Query: 494 PKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEE 553
K FT E + + K K E F +S D +E E
Sbjct: 485 KKGFT--------------EVKSQNGEFMTHKLKHTE---NTFSRPGGRASVDTKEAEGA 527
Query: 554 LQGDDGVNVEE----DGKT------KKSQKDDE-----EQIAKYRQ-LLQVIQEKEKKGK 597
Q + G +EE G+T K QK E E++ K R+ +V++E+E++ K
Sbjct: 528 PQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRK 587
Query: 598 ENDMEMEIKWVPGLKESAEEMVKNKLEGKDK--LTPWEQFLEKKKEKKRLKRKQKALAEE 655
+ + + +++ + EE+ + + E +K P + + KK K K +L E
Sbjct: 588 QEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIE 647
Query: 656 ASEEELPSDVD----LNDPYFAEEVKQIGINKKSVKSAKDGT 693
E L V + + A V +I + SA +GT
Sbjct: 648 ERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGT 689
Score = 48.5 bits (114), Expect = 3e-05
Identities = 57/286 (19%), Positives = 128/286 (44%), Gaps = 33/286 (11%)
Query: 545 EDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
E+E+ EE Q EE+ K K ++ +Q+ + + +Q E + KG++ + ++E
Sbjct: 361 EEEKRAAEERQR---ARAEEEEKAKVEEQKRNKQLEEKKHAMQ---ETKIKGEKVEQKIE 414
Query: 605 IKWVPGLKESAEEMVKN---KLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEEL 661
KWV K++ E+ ++ K +G++K T + EK +E K +K++ E+ +++
Sbjct: 415 GKWV-NEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKE 473
Query: 662 PSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKK 721
P EEVK KK K +++ + + D+K+
Sbjct: 474 PK----------EEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKE 523
Query: 722 HFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFK 781
++ + L + +++ + E ++FE + A+ L K
Sbjct: 524 AEGAPQVEAGKRLEELRRR----RGETESEEFEKLKQKQQEAALELEELK---------K 570
Query: 782 KTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPA 827
K + K+LEE+ ++R+++E + ++++ +++E +R+ + A
Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAA 616
Score = 45.8 bits (107), Expect = 2e-04
Identities = 67/365 (18%), Positives = 150/365 (41%), Gaps = 65/365 (17%)
Query: 546 DEEEIEEEL--QGDDGVNVEEDGKTKKSQKDDEEQIAKYR------QLLQVIQEKEKKGK 597
D+ E EL Q + + +E + + DDEE+ A+ R + L+ QE+E G+
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 598 END-MEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEK--KKEKKRLKRKQKALAE 654
D +E+ + +E+ ++EG D+ FLE+ ++E++R KR Q+AL
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAA----FLERLARREERRQKRLQEALER 117
Query: 655 EASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMD 714
+ + +D L+ P + ++ ++ + + S +E EIE + +
Sbjct: 118 QKEFDPTITDASLSLP--SRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKN 175
Query: 715 EDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKE--LIEDDFEVNVNDARFQAMYTSHLFN 772
+ D++++ +K E + K K+ + + + ++E+ + + ++ + +
Sbjct: 176 DWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISS 235
Query: 773 LDPSDPNFK------------------------------------KTKAMEKILEEKAR- 795
+P + K + +KI +E+AR
Sbjct: 236 EEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARI 295
Query: 796 ---------QRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARK 846
+RER+E E + ++++E +E QR + + + + E+ A +
Sbjct: 296 EAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 355
Query: 847 KQKVK 851
+Q++K
Sbjct: 356 RQRIK 360
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/286 (25%), Positives = 120/286 (41%), Gaps = 31/286 (10%)
Query: 89 LSQKKIKKKKT-----QTKKEIDSKNLVEKKKETKKANHKGSEN---KTDLDNSIGIKKM 140
+ +KK +K + + E ++K +K+ + K SE K + S K+
Sbjct: 426 IDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKES 485
Query: 141 KTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDS----SLEEKQRTLDSGTSEIV 196
+ + SPKK+SK+ T KN E+ + + + D S EE T +S +
Sbjct: 486 EEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSE 545
Query: 197 KSPRIECSKTRREMQSVVQ-----LIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGS 251
K +CS+ + E S + L D +G E + DK+ E DSE+ SE
Sbjct: 546 KESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSEN-SEF-E 603
Query: 252 DEESENEITSVG-RASGDDDGSEDDEEEDEDE---EEDEDEDSEDDDKSDSGPDLARGKG 307
D+ SE + G D+D E +EEED E +++ DE +++ + G + A K
Sbjct: 604 DDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKA 663
Query: 308 N--------IETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADE 345
E S + ED+ AD E E + + D + DE
Sbjct: 664 EEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDE 709
Score = 52.0 bits (123), Expect = 2e-06
Identities = 64/263 (24%), Positives = 110/263 (41%), Gaps = 40/263 (15%)
Query: 90 SQKKIKKKKTQTKKEIDSKNLVEKKKE------------TKKANHKGSENKTDLDNSIGI 137
S KK KKKT K + + L ++ ++ TK++ SE ++D D S
Sbjct: 498 SPKKESKKKT-LKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSE-- 554
Query: 138 KKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVK 197
K+ + + + + N K +E ++K E N++ + + E D G+ +++
Sbjct: 555 KQSEDGSEREFEENGLEKDLDEEGSEKELHE--NVLDKELEENDSENSEFEDDGSEKVLD 612
Query: 198 SPRIEC-----SKTRREMQSVVQLIMTRDSDG-----YENSTDGEMCDKDALEEDS-ESV 246
E S + E + + + +SD Y + E DK A E D+ E +
Sbjct: 613 EEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKL 672
Query: 247 SEIGSDEESEN----EITSVGRASGDDDGSED---DEEEDEDEEEDEDEDSEDD----DK 295
E D+E E+ E+ +DD S + DEEED E+ +D D
Sbjct: 673 FEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGS 732
Query: 296 SDSGPDLARGKGNIETSSEDEDD 318
+ GP L+ G I +S +D+DD
Sbjct: 733 VEEGP-LSTGSSFILSSDDDDDD 754
Score = 43.1 bits (100), Expect = 0.001
Identities = 56/229 (24%), Positives = 96/229 (41%), Gaps = 29/229 (12%)
Query: 524 RKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYR 583
++ KK+ L + + LA SED+ E E + EED K+S +D E+
Sbjct: 501 KESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEK----- 555
Query: 584 QLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKK 643
Q E++ +EN +E ++ KE E ++ +LE D +F + E
Sbjct: 556 ---QSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSEN--SEFEDDGSE-- 608
Query: 644 RLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIER 703
K L EE SE E D D + E+ + + +S + + + E+ +E
Sbjct: 609 ------KVLDEEGSEREFDEDSDEKEE--EEDTYEKVFDDESDEKEDEEYADEKGLEAAD 660
Query: 704 QKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDD 752
+KAE E + +K F + E ++ K+ + +K L EDD
Sbjct: 661 KKAE-------EGDADEKLFEESDDKEDEDADGKEVEDADEK--LFEDD 700
Score = 40.0 bits (92), Expect = 0.009
Identities = 75/378 (19%), Positives = 147/378 (38%), Gaps = 95/378 (25%)
Query: 516 HERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDD 575
HER+ ++ F MDF ED+ + E++ D V + G+ +K D
Sbjct: 262 HERVVIIKNMFHP-----MDF--------EDDPLVLNEIREDLRVECSKFGQIRKLLLFD 308
Query: 576 EEQIAKYRQLLQVIQEKEKKGKEND---MEMEIKWVPGLKESAE--------EMVKNKLE 624
V + +E D ++ +W G + +A+ ++ + E
Sbjct: 309 RHPDG-------VASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSRE 361
Query: 625 GKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASE-------EELPSDVDLNDPYFAEEVK 677
+++L WE FL + + L+R A E + E PS +N A +
Sbjct: 362 REERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMA 421
Query: 678 -QIGINKKSVKSAKDG--------------TSPEEEIE--------------------IE 702
+ I++K + +DG +SPE+E E
Sbjct: 422 FEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCS 481
Query: 703 RQKAEMALLMMDEDEDSKKHFNYNKIVEH------------QNLSKKKKKQLMKKKELIE 750
++++E + +EDS K + K +++ +L+K+ ++++ KE E
Sbjct: 482 QKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEE 541
Query: 751 DDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKK 810
DD E ++ S + D S+ F++ +EK L+E+ ++E E L + +++
Sbjct: 542 DDSEKESDED------CSEKQSEDGSEREFEE-NGLEKDLDEEGSEKELHENVLDKELEE 594
Query: 811 KE---SEIEKESQRKSID 825
+ SE E + K +D
Sbjct: 595 NDSENSEFEDDGSEKVLD 612
Score = 32.0 bits (71), Expect = 2.5
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 16/153 (10%)
Query: 516 HERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKK--SQK 573
HE + L+++ ++ + + +F+ + DEE E E D EE+ +K +
Sbjct: 584 HENV--LDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDE 641
Query: 574 DDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWE 633
DE++ +Y + ++ +KK +E D + + L E +++ +GK+ E
Sbjct: 642 SDEKEDEEYAD-EKGLEAADKKAEEGDADEK------LFEESDDKEDEDADGKEVEDADE 694
Query: 634 QFLEKKKEKKRLKRKQKALAEEASEEELPSDVD 666
+ E ++L + EE S E+L D D
Sbjct: 695 KLFEDDDSNEKLFDE-----EEDSSEKLFDDSD 722
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/286 (25%), Positives = 120/286 (41%), Gaps = 31/286 (10%)
Query: 89 LSQKKIKKKKT-----QTKKEIDSKNLVEKKKETKKANHKGSEN---KTDLDNSIGIKKM 140
+ +KK +K + + E ++K +K+ + K SE K + S K+
Sbjct: 426 IDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKES 485
Query: 141 KTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDS----SLEEKQRTLDSGTSEIV 196
+ + SPKK+SK+ T KN E+ + + + D S EE T +S +
Sbjct: 486 EEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSE 545
Query: 197 KSPRIECSKTRREMQSVVQ-----LIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGS 251
K +CS+ + E S + L D +G E + DK+ E DSE+ SE
Sbjct: 546 KESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSEN-SEF-E 603
Query: 252 DEESENEITSVG-RASGDDDGSEDDEEEDEDE---EEDEDEDSEDDDKSDSGPDLARGKG 307
D+ SE + G D+D E +EEED E +++ DE +++ + G + A K
Sbjct: 604 DDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKA 663
Query: 308 N--------IETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADE 345
E S + ED+ AD E E + + D + DE
Sbjct: 664 EEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDE 709
Score = 52.0 bits (123), Expect = 2e-06
Identities = 64/263 (24%), Positives = 110/263 (41%), Gaps = 40/263 (15%)
Query: 90 SQKKIKKKKTQTKKEIDSKNLVEKKKE------------TKKANHKGSENKTDLDNSIGI 137
S KK KKKT K + + L ++ ++ TK++ SE ++D D S
Sbjct: 498 SPKKESKKKT-LKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSE-- 554
Query: 138 KKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVK 197
K+ + + + + N K +E ++K E N++ + + E D G+ +++
Sbjct: 555 KQSEDGSEREFEENGLEKDLDEEGSEKELHE--NVLDKELEENDSENSEFEDDGSEKVLD 612
Query: 198 SPRIEC-----SKTRREMQSVVQLIMTRDSDG-----YENSTDGEMCDKDALEEDS-ESV 246
E S + E + + + +SD Y + E DK A E D+ E +
Sbjct: 613 EEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKL 672
Query: 247 SEIGSDEESEN----EITSVGRASGDDDGSED---DEEEDEDEEEDEDEDSEDD----DK 295
E D+E E+ E+ +DD S + DEEED E+ +D D
Sbjct: 673 FEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGS 732
Query: 296 SDSGPDLARGKGNIETSSEDEDD 318
+ GP L+ G I +S +D+DD
Sbjct: 733 VEEGP-LSTGSSFILSSDDDDDD 754
Score = 43.1 bits (100), Expect = 0.001
Identities = 56/229 (24%), Positives = 96/229 (41%), Gaps = 29/229 (12%)
Query: 524 RKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYR 583
++ KK+ L + + LA SED+ E E + EED K+S +D E+
Sbjct: 501 KESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEK----- 555
Query: 584 QLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKK 643
Q E++ +EN +E ++ KE E ++ +LE D +F + E
Sbjct: 556 ---QSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSEN--SEFEDDGSE-- 608
Query: 644 RLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIER 703
K L EE SE E D D + E+ + + +S + + + E+ +E
Sbjct: 609 ------KVLDEEGSEREFDEDSDEKEE--EEDTYEKVFDDESDEKEDEEYADEKGLEAAD 660
Query: 704 QKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDD 752
+KAE E + +K F + E ++ K+ + +K L EDD
Sbjct: 661 KKAE-------EGDADEKLFEESDDKEDEDADGKEVEDADEK--LFEDD 700
Score = 40.0 bits (92), Expect = 0.009
Identities = 75/378 (19%), Positives = 147/378 (38%), Gaps = 95/378 (25%)
Query: 516 HERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDD 575
HER+ ++ F MDF ED+ + E++ D V + G+ +K D
Sbjct: 262 HERVVIIKNMFHP-----MDF--------EDDPLVLNEIREDLRVECSKFGQIRKLLLFD 308
Query: 576 EEQIAKYRQLLQVIQEKEKKGKEND---MEMEIKWVPGLKESAE--------EMVKNKLE 624
V + +E D ++ +W G + +A+ ++ + E
Sbjct: 309 RHPDG-------VASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEETSRE 361
Query: 625 GKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASE-------EELPSDVDLNDPYFAEEVK 677
+++L WE FL + + L+R A E + E PS +N A +
Sbjct: 362 REERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETATGMA 421
Query: 678 -QIGINKKSVKSAKDG--------------TSPEEEIE--------------------IE 702
+ I++K + +DG +SPE+E E
Sbjct: 422 FEEPIDEKKFEKTEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCS 481
Query: 703 RQKAEMALLMMDEDEDSKKHFNYNKIVEH------------QNLSKKKKKQLMKKKELIE 750
++++E + +EDS K + K +++ +L+K+ ++++ KE E
Sbjct: 482 QKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEE 541
Query: 751 DDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKK 810
DD E ++ S + D S+ F++ +EK L+E+ ++E E L + +++
Sbjct: 542 DDSEKESDED------CSEKQSEDGSEREFEE-NGLEKDLDEEGSEKELHENVLDKELEE 594
Query: 811 KE---SEIEKESQRKSID 825
+ SE E + K +D
Sbjct: 595 NDSENSEFEDDGSEKVLD 612
Score = 32.0 bits (71), Expect = 2.5
Identities = 34/153 (22%), Positives = 68/153 (44%), Gaps = 16/153 (10%)
Query: 516 HERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKK--SQK 573
HE + L+++ ++ + + +F+ + DEE E E D EE+ +K +
Sbjct: 584 HENV--LDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDE 641
Query: 574 DDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWE 633
DE++ +Y + ++ +KK +E D + + L E +++ +GK+ E
Sbjct: 642 SDEKEDEEYAD-EKGLEAADKKAEEGDADEK------LFEESDDKEDEDADGKEVEDADE 694
Query: 634 QFLEKKKEKKRLKRKQKALAEEASEEELPSDVD 666
+ E ++L + EE S E+L D D
Sbjct: 695 KLFEDDDSNEKLFDE-----EEDSSEKLFDDSD 722
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 64.7 bits (156), Expect = 3e-10
Identities = 64/274 (23%), Positives = 110/274 (40%), Gaps = 30/274 (10%)
Query: 76 DSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNSI 135
D N +D +S+KK ++K + +++E + + E+KK+ ++ + KG E D +
Sbjct: 918 DEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETEN 977
Query: 136 GIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEI 195
G K K K + +PK + + K K + K I+ + DSS E+K + D G
Sbjct: 978 GPKPKKRRPP-KAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEG---- 1032
Query: 196 VKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDG------------EMCDKDALEEDS 243
PR S + + + + +SD EN + D+D+ +
Sbjct: 1033 --HPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQP 1090
Query: 244 ESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLA 303
E+S+NE GR+ SE+D E + E D SG
Sbjct: 1091 SRKRRPSGSEQSDNESVQSGRS--HSGVSENDSRPASPSAESDHESERGSDNEGSG---- 1144
Query: 304 RGKGNIETSSEDEDDTADLFPEESGFEHAWRELD 337
+G GN E E + ++ + G EH + D
Sbjct: 1145 QGSGN-----ESEPEGSNNEASDRGSEHGSDDSD 1173
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 63.9 bits (154), Expect = 6e-10
Identities = 49/250 (19%), Positives = 91/250 (36%), Gaps = 9/250 (3%)
Query: 72 YDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDL 131
Y+ +S N +G DSK + + K + KG + +D
Sbjct: 493 YNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDS 552
Query: 132 DNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSG 191
D+S +S DS+ S + + + + + + +S + + S
Sbjct: 553 DSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSD 612
Query: 192 TSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGS 251
+S+ S + ++ E S DSD +S+D D + S+S + S
Sbjct: 613 SSDSSDSSDSKSDSSKSESDS-------SDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 252 DEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIET 311
+ S++ +S +S D S D + + E DS D SDS + N +
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSD--SSDSSNSNS 723
Query: 312 SSEDEDDTAD 321
S D +++D
Sbjct: 724 SDSDSSNSSD 733
Score = 63.9 bits (154), Expect = 6e-10
Identities = 48/262 (18%), Positives = 98/262 (37%), Gaps = 1/262 (0%)
Query: 61 SHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQT-KKEIDSKNLVEKKKETKK 119
S S + D D SDS + DS S K K+++ + DSK+ +
Sbjct: 591 SDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDS 650
Query: 120 ANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDS 179
+++ S + ++ NS S S+ S DS + + + + + ++DS
Sbjct: 651 SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710
Query: 180 SLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDAL 239
+ + +S +S+ S + S + S + SD ++S D
Sbjct: 711 DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770
Query: 240 EEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSG 299
+ S+S S + +++ +S S + S + + + + + + S D S+S
Sbjct: 771 SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 300 PDLARGKGNIETSSEDEDDTAD 321
+ + S D D +D
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSD 852
Score = 62.8 bits (151), Expect = 1e-09
Identities = 53/251 (21%), Positives = 86/251 (34%), Gaps = 5/251 (1%)
Query: 73 DLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLD 132
D S S+S+ S DSK+ S + DS N + ++ S + +D
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 133 NSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGT 192
NS S S S DS + + + N +DSS + +
Sbjct: 685 NSSDSSDSSDSSN---SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSS 741
Query: 193 SEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSD 252
S S + S + SD ++S D + S+S S
Sbjct: 742 DSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSS 801
Query: 253 EESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDS--GPDLARGKGNIE 310
+ S + +S S D D S + + + D S+ D SDS G D +
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861
Query: 311 TSSEDEDDTAD 321
++S D D++D
Sbjct: 862 SNSSDSSDSSD 872
Score = 62.0 bits (149), Expect = 2e-09
Identities = 48/255 (18%), Positives = 84/255 (32%)
Query: 63 STTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANH 122
S + D D SDS + +S S + + DS + E + +N
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 123 KGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLE 182
S + +D +S S SN S DS + + + + +++SS
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Query: 183 EKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEED 242
+ S + S + S + SD ++S + D +
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Query: 243 SESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDL 302
S+S S + S++ ++ S D S D + + + DS D +S
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Query: 303 ARGKGNIETSSEDED 317
G GN S D D
Sbjct: 1274 KSGNGNNNGSDSDSD 1288
Score = 61.2 bits (147), Expect = 4e-09
Identities = 52/260 (20%), Positives = 92/260 (35%), Gaps = 6/260 (2%)
Query: 63 STTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANH 122
S + D D S+S + + DS S + + DS N + + ++
Sbjct: 1010 SDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1069
Query: 123 KGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLE 182
S + +D +S S S+ S DS + + + + +++DSS
Sbjct: 1070 SDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1129
Query: 183 EKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEED 242
++ S E S + S + SD ++S D +
Sbjct: 1130 SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1189
Query: 243 SESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDD-DKSDSGPD 301
S+S S + S++ +S S D S D + + + +E DS D D SDS
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSS-- 1247
Query: 302 LARGKGNIETSSEDEDDTAD 321
+ SS+ D T+D
Sbjct: 1248 ---NSSDSSDSSDSSDSTSD 1264
Score = 60.8 bits (146), Expect = 5e-09
Identities = 50/266 (18%), Positives = 92/266 (34%), Gaps = 1/266 (0%)
Query: 63 STTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANH 122
S + D D S+S + + DS S + + DS + + + ++
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063
Query: 123 KGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLE 182
S + +D +S S SN S DS + + + + ++DSS
Sbjct: 1064 SDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123
Query: 183 EKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEED 242
+ S + S + S + SD ++S + D +
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183
Query: 243 SESVSEIGSDEESENEITSVGRASGDD-DGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPD 301
S+S S + S++ +S S D D S+ + D + D + +E D SDS
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243
Query: 302 LARGKGNIETSSEDEDDTADLFPEES 327
+ + S D D+ +ES
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDES 1269
Score = 60.1 bits (144), Expect = 9e-09
Identities = 52/260 (20%), Positives = 90/260 (34%), Gaps = 4/260 (1%)
Query: 63 STTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANH 122
S + D D SDS + G DS + S + + + DS N + +
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDS-SNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNES 888
Query: 123 KGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSS-L 181
S + +D NS S S+ S DS E + + + +++DSS
Sbjct: 889 SNSSDSSDSSNS-SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS 947
Query: 182 EEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEE 241
+ + DS S + + + DS +S+D +
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 242 DSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPD 301
DS S+ + +S N S +S D S+ + D + D + S D SDS
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDS-SNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066
Query: 302 LARGKGNIETSSEDEDDTAD 321
+ + S D +++D
Sbjct: 1067 SDSSDSSDSSDSSDSSESSD 1086
Score = 59.3 bits (142), Expect = 1e-08
Identities = 48/247 (19%), Positives = 90/247 (36%), Gaps = 11/247 (4%)
Query: 75 SDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNS 134
S SDS+ S DS S + + DS + + + ++ K +K++ D+S
Sbjct: 576 SSSDSDSSDSDSSDSSDSD-SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSS 634
Query: 135 IGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSE 194
K +S DSN S D+ + + + + ++DSS + +
Sbjct: 635 DSDSKSDSS-----DSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Query: 195 IVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEE 254
S S++ S DS +S++ D D+ S S SD
Sbjct: 690 SDSSDSSNSSESSDSSDS-----SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 255 SENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSE 314
++ ++ +S D S + D + D + S D +DS + + S
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 315 DEDDTAD 321
+ D++D
Sbjct: 805 NSSDSSD 811
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/246 (19%), Positives = 89/246 (36%), Gaps = 6/246 (2%)
Query: 73 DLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLD 132
D SDS + DS S + + DS + + + ++ S + +D
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1121
Query: 133 NSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGT 192
NS S SN S DS E + + + ++DSS + + DS
Sbjct: 1122 NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS--DSSDSSDSSN 1179
Query: 193 SEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSD 252
S S + S + S + SD ++S + D + S+S S
Sbjct: 1180 S----SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESS 1235
Query: 253 EESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETS 312
+ S++ +S S D S D + D ++ D S+ + +++G D +++
Sbjct: 1236 DSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
Query: 313 SEDEDD 318
DD
Sbjct: 1296 HSTSDD 1301
Score = 57.0 bits (136), Expect = 7e-08
Identities = 50/259 (19%), Positives = 100/259 (38%), Gaps = 9/259 (3%)
Query: 63 STTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANH 122
S + D D SDS SN S + + S + + DS N + + ++
Sbjct: 783 SDSNDSSNSSDSSDS-SNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841
Query: 123 KGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLE 182
S + +D +S + +S S+ S DS + + N +++DSS
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNS----SDSSDSSDSSNSSDSSDSSDSNESSNSSDSS-- 895
Query: 183 EKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEED 242
+ + DS +S+ S + S + S + +S+ ++S + D
Sbjct: 896 DSSNSSDSDSSDSSNSS--DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953
Query: 243 SESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDL 302
S+S + S S++ ++ +S + S+ + D + D + S D SDS
Sbjct: 954 SDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1013
Query: 303 ARGKGNIETSSEDEDDTAD 321
+ ++S D +++D
Sbjct: 1014 DSSNSSDSSNSSDSSNSSD 1032
Score = 53.9 bits (128), Expect = 6e-07
Identities = 55/265 (20%), Positives = 93/265 (35%), Gaps = 42/265 (15%)
Query: 57 GRPISHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKE 116
G + HS T SDSN G DS K ++ D N ++
Sbjct: 433 GNKVGHSNT----------GSDSNSDGYDSYDFDDKSMQG---------DDPNSSDESNG 473
Query: 117 TKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHT 176
AN + N + ++ S + K + N S K +++ + + N +
Sbjct: 474 NDDANSESDNNSSSRGDA-----SYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNG 528
Query: 177 TDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDK 236
++ + DSG + S + S DS ++S D
Sbjct: 529 NGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSS--------DSSDSDSSDSNSSSDS 580
Query: 237 DALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKS 296
D+ + DS S+ S + S + +S S D S D + D + E + S+ D KS
Sbjct: 581 DSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKS 640
Query: 297 DSGPDLARGKGNIETSSEDEDDTAD 321
DS +++S D D +D
Sbjct: 641 DSS----------DSNSSDSSDNSD 655
Score = 52.4 bits (124), Expect = 2e-06
Identities = 64/316 (20%), Positives = 110/316 (34%), Gaps = 36/316 (11%)
Query: 48 KLNYAVDKR--GRPISHSTTEDLKRFYDL-------SDSDSNLSGEDSKALSQKKIKKK- 97
KLN+ KR R S T + + D S + N++ E K K+ K +
Sbjct: 346 KLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQH 405
Query: 98 -----KTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNI 152
K K + + N+ ++++ N G N NS G + D
Sbjct: 406 GMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDS------YDFDDKS 459
Query: 153 SPKKDSKEFTQKNKKEKKNIVQHTTDSSLEE----KQRTLDSGTSEIVKSPRIECSKTRR 208
D + N + N SS + + D+G K + S +
Sbjct: 460 MQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTS 519
Query: 209 EMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGD 268
+ T +SD N +G D + + + S+ + S++ +S S D
Sbjct: 520 D---------TNNSDSNGNGNNGN--DDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSD 568
Query: 269 DDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESG 328
D S+ + D D + + DS D D SDS + + S D D++D + S
Sbjct: 569 SDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 329 FEHAWRELDKDAPRAD 344
E + D + +D
Sbjct: 629 SESDSSDSDSKSDSSD 644
Score = 40.8 bits (94), Expect = 0.005
Identities = 41/141 (29%), Positives = 61/141 (43%), Gaps = 21/141 (14%)
Query: 224 GYENSTDGE--MCDKDALEED--SESVSEIGSDEES--ENEIT-SVGRASGDDD------ 270
G NSTD E + + E SE +I S E E+T G +G D+
Sbjct: 188 GSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPS 247
Query: 271 --GSEDDEEE----DEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFP 324
G+++DE+E DEDEE +DS ++ K G D GK + SS ++ + +
Sbjct: 248 GNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQD--HGKEDDHDSSIGQNSDSKEYY 305
Query: 325 EESGFEHAWRELDKDAPRADE 345
+ G E E+D D E
Sbjct: 306 DPEGKEDPHNEVDGDKTSKSE 326
Score = 35.8 bits (81), Expect = 0.17
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 20/156 (12%)
Query: 178 DSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENST-----DGE 232
D +E R + TSEI +P+I + + V T + G +NS +G
Sbjct: 197 DEIIENSCRN-EGNTSEI--TPQINSKRNGTKEAEVTP--GTGEDAGLDNSDGSPSGNGA 251
Query: 233 MCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSED 292
D+D D E E G+ ++S N S G+ G D G EDD + + D E +
Sbjct: 252 DEDEDEGSGDDED-EEAGNGKDSSN--NSKGQ-EGQDHGKEDDHDSSIGQNSDSKEYYDP 307
Query: 293 DDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESG 328
+ K D ++ K +S+ E+++A + PE++G
Sbjct: 308 EGKEDPHNEVDGDK-----TSKSEENSAGI-PEDNG 337
Score = 30.4 bits (67), Expect = 7.3
Identities = 24/118 (20%), Positives = 38/118 (32%)
Query: 63 STTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANH 122
S + D D SDS + DS S + + DS + + + ++
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237
Query: 123 KGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSS 180
S + +D NS S DSN SK N + +DS+
Sbjct: 1238 SDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 63.9 bits (154), Expect = 6e-10
Identities = 68/332 (20%), Positives = 134/332 (40%), Gaps = 31/332 (9%)
Query: 17 AKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDLSD 76
A+D + +KD+K K ++ KK V ++ E+ ++ + +
Sbjct: 305 AEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEE 364
Query: 77 SDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNSIG 136
L ++K +++++++K + KK+ + + KKE K E + + ++
Sbjct: 365 RIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATL- 423
Query: 137 IKKMKTSCKFKIDSNIS-PKKDSKEFTQKNKKEKKNIVQHTTDSSLE--EKQRTLDSGTS 193
K+ + ++ S S PKK +K KK + + S+E ++ G
Sbjct: 424 --KLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVP 481
Query: 194 EIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDE 253
E ++P + + E++ D + D +A+ D E+ G+
Sbjct: 482 EKEETPP------------------PVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKV 523
Query: 254 ESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDD-------DKSDSGPDLARGK 306
E + +++ ED+E E+E+EEE E E SE D D+ DSG L +
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKP 583
Query: 307 GNIETSSEDEDDTADLFPEESGFEHAWRELDK 338
+S + D D EE ++ A R ++K
Sbjct: 584 SKEMSSDSEYDSDDDRTKEERAYDKAKRRIEK 615
Score = 61.6 bits (148), Expect = 3e-09
Identities = 82/373 (21%), Positives = 143/373 (38%), Gaps = 63/373 (16%)
Query: 15 RVAKDPRFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGRPISHSTTEDLKRFYDL 74
R K+ E +KD+ + K + F ++ K VD P S E
Sbjct: 251 RKLKEKEELETGKKDQSKQ--KESQRKFEEETVKSKVTVDTGVIPASEEKAE-------- 300
Query: 75 SDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKG-SENKTDLDN 133
+ + ED +KK KKK + +KE K EKKK KA K E L
Sbjct: 301 ----TPTAAEDDNEGDKKKKDKKKKKGEKEEKEK---EKKKGPSKATVKAMQEALAKLKE 353
Query: 134 SIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTS 193
+K + + K + K+ +E ++ K+E+K + L+++ + L
Sbjct: 354 EEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQR 413
Query: 194 EIVKSPRIECSKTRREMQSVVQLIMTRDS--------------------DGYENSTDGEM 233
E R T + +Q+ + ++DS + E S E+
Sbjct: 414 EA----RARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMEL 469
Query: 234 CD-----KDALEEDSESVSEIGSDEESENEITSVG--RASGDDDGSED------------ 274
C + + E E+ + +EE + E + A D+ +E
Sbjct: 470 CAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKE 529
Query: 275 --DEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFEHA 332
+EEE+E+EEE+EDE+SE++++ + + + G E S+++D L + S +
Sbjct: 530 NPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSS 589
Query: 333 WRELDKDAPRADE 345
E D D R E
Sbjct: 590 DSEYDSDDDRTKE 602
Score = 50.1 bits (118), Expect = 9e-06
Identities = 68/322 (21%), Positives = 143/322 (44%), Gaps = 28/322 (8%)
Query: 508 EITWDETDHERITMLNRKFKKEELLD-MDFQAYLASSSEDEEEIEEELQGD-DGVNVEED 565
E+ + D + RKF++E + + + +SE++ E + D +G ++D
Sbjct: 258 ELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKD 317
Query: 566 GKTKKSQKDDEEQIAKY---RQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNK 622
K KK +K+++E+ K + ++ +QE K KE + + + +K E K K
Sbjct: 318 KKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRK 377
Query: 623 LEGKDKLTPWEQFLEKKKEKK-RLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGI 681
E + + E+ +K+KE+K RLK++ K L + E ++ L + ++ G+
Sbjct: 378 EEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATL------KLLQAQGV 431
Query: 682 NKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQ 741
S KD + I ++++ ++ + ++ V Q + +K++
Sbjct: 432 EVPS----KDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETP 487
Query: 742 LMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKE 801
+ E ED + ++D ++AM SD +K + + +E K E +E
Sbjct: 488 PPVEPEEEEDTEDAGLDD--WEAM---------ASDEETEKVEGNKVHIEVKENPEEEEE 536
Query: 802 QELTQAIKKKESEIEKESQRKS 823
+E + + +ESE E+E + +S
Sbjct: 537 EE-EEEEEDEESEEEEEEEGES 557
Score = 49.7 bits (117), Expect = 1e-05
Identities = 118/589 (20%), Positives = 223/589 (37%), Gaps = 100/589 (16%)
Query: 76 DSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETK----------------- 118
+++ + +D K KK +K K Q+ + DS+ L +K ++K
Sbjct: 86 NNEEEFTSKDKK----KKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDD 141
Query: 119 --------------KANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQK 164
K+N K ++ D DNS IK+ + +I+S+ +S EF Q
Sbjct: 142 DFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKE-----RSRINSSGESGDESDEFLQS 196
Query: 165 NKKEKKNIVQH---TTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRD 221
K +KKN +S E+ + T K+ + E + +R+ + +L ++
Sbjct: 197 RKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD-EEKAKLRKLKE 255
Query: 222 SDGYENSTDGEMCDKDAL----EEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEE 277
+ E + K++ EE +S + + +E + + +DD D ++
Sbjct: 256 KEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKK 315
Query: 278 EDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELD 337
+D+ +++ E E+ E + K GP A K E ++ +++ EE E R +
Sbjct: 316 KDKKKKKGEKEEKEKEKK--KGPSKATVKAMQEALAKLKEEEERQKREEE--ERIKRLEE 371
Query: 338 KDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEE 397
+A R +E RL + + K K+ K +G ++ + + +K
Sbjct: 372 LEAKRKEE--ERLEQEKRERKKQKEKERK---ERLKKEGKLLTKSQREARARAEATLKLL 426
Query: 398 QVQGPVELLSIPEDAPEKDWTSREKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLE 457
Q QG + P KD + +K Y+ K+ K KI + + E
Sbjct: 427 QAQG--------VEVPSKD-SLPKKRPIYEDKKRK---------------KIPQQLESKE 462
Query: 458 FESSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDE-TDH 516
S A EV K T + E T D D
Sbjct: 463 VSESMELC-----------------AAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDD 505
Query: 517 ERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDE 576
+ + +K E + + E+EEE EEE + EE+G+++ S+ D+E
Sbjct: 506 WEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEE 565
Query: 577 -EQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLE 624
E+++ + + + +K K +D E + +E A + K ++E
Sbjct: 566 DEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIE 614
Score = 48.9 bits (115), Expect = 2e-05
Identities = 129/708 (18%), Positives = 262/708 (37%), Gaps = 109/708 (15%)
Query: 102 KKEIDSKNLVEKKKETKKANHKGSENKTDLDN----SIGIKKMKTSCKFKIDSNISPKKD 157
K++ K+ +KKKE KK + + +L+ + GIK + + K N +
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFT 92
Query: 158 SKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLI 217
SK+ +K +K KK LE+K SK+++ + V++
Sbjct: 93 SKDKKKKGQKGKKQSFDDNDSEELEDKD------------------SKSKKTAKPKVEMY 134
Query: 218 MTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEE 277
D D D K A + +S + EE E+ + S + E +E
Sbjct: 135 SGSDDD-----DDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDE 189
Query: 278 EDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADL----FPEESGFEHAW 333
DE + + + + + K+ GP NIE+ +ED+D + + + E
Sbjct: 190 SDEFLQSRKGQ--KKNQKNKPGP-------NIESGNEDDDASFKIKTVAQKKAEKKERER 240
Query: 334 RELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKER 393
++ D++ + ++ + + D+ K K+ F K V + P+
Sbjct: 241 KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPA------ 294
Query: 394 MKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQFKRLKYYYAVVDCDSPETASKIYEDC 453
EE+ + P A E D +K +D + K+ K ++
Sbjct: 295 -SEEKAETPT--------AAEDDNEGDKKKKDKKKKK---------------GEKEEKEK 330
Query: 454 DGLEFESSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDE 513
+ + S + ++ + ++E + E + + E+
Sbjct: 331 EKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLE--------------ELEAKR 376
Query: 514 TDHERITMLNRKFKKE------ELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGK 567
+ ER+ R+ KK+ E L + + S E E L+ VE K
Sbjct: 377 KEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSK 436
Query: 568 TKKSQKDDEEQIAKYRQLLQVIQEKE-KKGKENDMEMEI--KWVPGLKESAEEMVKNKLE 624
+K + K +++ Q ++ KE + E +E+ + VP +E+ + + E
Sbjct: 437 DSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEE 496
Query: 625 GKDK--LTPWEQFL-EKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGI 681
+ L WE +++ EK + + E EEE + + D EE ++ G
Sbjct: 497 DTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGE 556
Query: 682 NKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQ 741
++ S +G +E++ E+ + ++ S ++ + + + K K+
Sbjct: 557 SEGS-----EGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKR 611
Query: 742 LMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKI 789
++K+ L + NVN + +A L ++D KTK ++K+
Sbjct: 612 RIEKRRL---EHSKNVNTEKLRAPIICVLGHVDTG-----KTKILDKL 651
Score = 48.1 bits (113), Expect = 3e-05
Identities = 65/300 (21%), Positives = 133/300 (44%), Gaps = 42/300 (14%)
Query: 550 IEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVP 609
IE + DD + KK++K + E+ + + ++ + KEK+ E + + K
Sbjct: 212 IESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKE 271
Query: 610 GLKESAEEMVKNKL--------EGKDKL-TPWEQFLEKKKEKKRLKRKQKALAEEASEEE 660
++ EE VK+K+ ++K TP + + +KK+ +K+K +E E+E
Sbjct: 272 SQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKE 331
Query: 661 LPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSP-EEEIEIERQKAEMALLMMDEDEDS 719
K+ G +K +VK+ ++ + +EE E ++++ E + ++E E
Sbjct: 332 ----------------KKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAK 375
Query: 720 KKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDD--FEVNVNDARFQAMYTSHLFNLD--- 774
+K + +E + +KK+K+ +K+ L ++ + +AR +A T L
Sbjct: 376 RKE---EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVE 432
Query: 775 -PSDPNFKK------TKAMEKILEEKARQRERKEQELTQAIKKKESEI-EKESQRKSIDP 826
PS + K K +KI ++ + + EL A++ E + EKE ++P
Sbjct: 433 VPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEP 492
Score = 47.8 bits (112), Expect = 4e-05
Identities = 78/344 (22%), Positives = 148/344 (43%), Gaps = 50/344 (14%)
Query: 506 TVEITWDETDHERITMLNRKFK-----KEELLDMDFQAYLASSSEDEEEIEEELQGDDGV 560
TV + E + E T ++K K K+ D D + S+ ++ + +++ G
Sbjct: 78 TVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGS 137
Query: 561 NVEED---------GKTKKSQK------DDEEQIAKYRQLLQVIQEKEKKGKENDMEMEI 605
+ ++D GK +KS K +DE+ K ++ ++ E G E+D ++
Sbjct: 138 DDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGES-GDESDEFLQS 196
Query: 606 KWVPGLKESAEEM----VKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEEL 661
+ G K++ + +++ E D + +KK EKK +RK++ E+A +L
Sbjct: 197 R--KGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD-EEKAKLRKL 253
Query: 662 PSDVDLND---PYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDED 718
+L ++ Q +++VKS T I +KAE D++E
Sbjct: 254 KEKEELETGKKDQSKQKESQRKFEEETVKSKV--TVDTGVIPASEEKAETPTAAEDDNEG 311
Query: 719 SKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDP 778
KK KK KK+ +KE E + + + A +AM + L L +
Sbjct: 312 DKK--------------KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA-LAKLKEEEE 356
Query: 779 NFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRK 822
K+ + E+I + + +RKE+E + +K+E + +KE +RK
Sbjct: 357 RQKREEE-ERIKRLEELEAKRKEEERLEQ-EKRERKKQKEKERK 398
Score = 46.2 bits (108), Expect = 1e-04
Identities = 71/304 (23%), Positives = 117/304 (38%), Gaps = 73/304 (24%)
Query: 546 DEEEIEEELQGDDGVNVEEDGKTK-KSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
D + + E++G +E K+K K +K+ ++Q +L+ ++E + +
Sbjct: 18 DLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQ------- 70
Query: 605 IKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEE----- 659
G+K E + E + E+F K K+KK K K+++ + SEE
Sbjct: 71 -----GIKADRETVAVKPTENNE-----EEFTSKDKKKKGQKGKKQSFDDNDSEELEDKD 120
Query: 660 -----------ELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEM 708
E+ S D +D + K G +KS K DG S E+E ++ K
Sbjct: 121 SKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKW-DG-SEEDEDNSKKIKERS 178
Query: 709 ALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTS 768
+ E D F Q+ +KK Q K IE E
Sbjct: 179 RINSSGESGDESDEFL-------QSRKGQKKNQKNKPGPNIESGNE-------------- 217
Query: 769 HLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESE----------IEKE 818
D +FK +K E+K R+R+++++E + K KE E +KE
Sbjct: 218 ------DDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKE 271
Query: 819 SQRK 822
SQRK
Sbjct: 272 SQRK 275
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 62.8 bits (151), Expect = 1e-09
Identities = 68/294 (23%), Positives = 119/294 (40%), Gaps = 40/294 (13%)
Query: 76 DSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNSI 135
DS S++ GED+ + ++ D K + +E ++ + K DLD +
Sbjct: 4715 DSKSDIKGEDNAI-----------EMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHM 4763
Query: 136 GIKKMKTSCKFKIDSNISPKKDSKEFTQK--NKKEKKNIVQHTTDSSLEEKQRTLDSGTS 193
G + K+D + D +E ++ NK E+ DS L K LDSG S
Sbjct: 4764 G--DLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNS 4821
Query: 194 EIVKSPR--------IECSKTRREMQSVVQLIMTRDSDGYENSTDG-------------- 231
KS + E + + + I RD D EN D
Sbjct: 4822 NKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYD--ENEVDPYHGNQEKVPEPEAL 4879
Query: 232 EMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSE 291
++ D L+ + ++ E +EE E E + ++ G E +E + + +++E + +
Sbjct: 4880 DLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQ 4939
Query: 292 DDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADE 345
+ ++ S D A G+ ++T ++D+D A PEE E +KD ADE
Sbjct: 4940 EPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKD-KEADE 4992
Score = 45.8 bits (107), Expect = 2e-04
Identities = 111/549 (20%), Positives = 198/549 (36%), Gaps = 88/549 (16%)
Query: 73 DLSDSDSNL-SGEDSKALSQKKIKKKKTQTK------------KEIDSKNLVEKKKETKK 119
+L D NL SG +K SQ+ K++K + + ++ID ++ E + +
Sbjct: 4808 ELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYH 4867
Query: 120 ANHKG--SENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTT 177
N + DL + + + D N D++E ++N E K +
Sbjct: 4868 GNQEKVPEPEALDLPDDLNLDSE--------DKNGGEDTDNEEGEEENPLEIKEKPEEAG 4919
Query: 178 DSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKD 237
+ E + D S+ + P S+ + D DG D ++
Sbjct: 4920 HEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDG-----DAAQHPEE 4974
Query: 238 ALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSD 297
EE +SV E D+E++ E G A E++E ED D EE E E + +
Sbjct: 4975 HSEEQQQSVEE--KDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHAS 5032
Query: 298 SGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDW 357
G G N++ + E A E+ EH D + E + +
Sbjct: 5033 CG---QTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKH 5089
Query: 358 DRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDW 417
R + SFK K G + + G + + V+ S E P +
Sbjct: 5090 TRKNTQ-------SFKRKPGQADNER----SMGDHNERVHKRLRTVDTDSHAEQGPAQQP 5138
Query: 418 TSREKLRDYQFKRLKYYYAVVDCDSPETASKIYEDC---DGLEFESSCSFIDLRFIPDDI 474
++ + D F+ +K D + + ASK + G + E +D
Sbjct: 5139 QAQVEDAD-AFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEE--------EIEDT 5189
Query: 475 TFDDEPKDVASEVNLTAYKP---KYFTSAAMG--TSTVEITWDETDHERITMLNRKFKKE 529
D E ++ ++ KP K T+A +G VEI +T+ ++ ++ K+
Sbjct: 5190 LMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKET 5249
Query: 530 E------------------LLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKS 571
E L+D FQ +L +E +E+E +L E + ++S
Sbjct: 5250 ENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQL---------EMWQPRES 5300
Query: 572 QKDDEEQIA 580
+EE++A
Sbjct: 5301 GNPEEEKVA 5309
Score = 45.4 bits (106), Expect = 2e-04
Identities = 133/664 (20%), Positives = 249/664 (37%), Gaps = 138/664 (20%)
Query: 232 EMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDE-DEDS 290
++ D+ EE E + G +++ E+ S G+D+ E E+ D + E +E
Sbjct: 4688 DVSDQIGNEEQVEDTFQKGQEKDKEDP-DSKSDIKGEDNAIEMSEDFDGKMHDGELEEQE 4746
Query: 291 EDDDKSDS-GPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRR 349
EDD+KSDS G DL + G++ D+ D E W + D++ +E +
Sbjct: 4747 EDDEKSDSEGGDLDKHMGDLNGEEADKLD-----------ERLWGDDDEEEDEEEEDNKT 4795
Query: 350 ----LAVCNMDWDRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVEL 405
+ D + + D L NS K K S+ K+ KEE
Sbjct: 4796 EETGPGMDEEDSELVAKDDNLDSGNSNKDK-----------SQQDKKEEKEE-------- 4836
Query: 406 LSIPEDAPEKDWTSREKL--RDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCS 463
+ +D + + E++ RDY + Y+ K+ E + L+
Sbjct: 4837 -AEADDGGQGEDKINEQIDERDYDENEVDPYHG--------NQEKVPEP-EALD------ 4880
Query: 464 FIDLRFIPDDITFDDEPK--------DVASEVNLTAYKPKYFTSAAMGTSTVEITWDETD 515
+PDD+ D E K + E N K K G E ETD
Sbjct: 4881 ------LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEK---PEEAGHEAEERGETETD 4931
Query: 516 HERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDD 575
N +E + S +D+ E EEE+ D G + ++ + ++
Sbjct: 4932 Q------NESQSPQEPEE-------GPSEDDKAEGEEEM--DTGADDQDGDAAQHPEEHS 4976
Query: 576 EEQIAKYRQLLQVIQEKEKKGKENDME---MEIKWVPGLKE-----SAEEMVKNKLEGKD 627
EEQ Q ++EK+K+ E E + + P +E EE V LE K+
Sbjct: 4977 EEQ-------QQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKE 5029
Query: 628 KLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPS---DVDLNDPYFAEEVKQIGINKK 684
+ + +E + + ++ A +E +EE S D + + + + + Q+ K
Sbjct: 5030 HASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKH 5089
Query: 685 SVKSAKDGTSPEEEIEIER------QKAEMALLMMD-----------------EDEDSKK 721
+ K+ + + + ER ++ L +D ED D+ +
Sbjct: 5090 TRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFE 5149
Query: 722 HFNYNK---IVEHQNLSKKKKKQLMKK--KELIEDDFEVNVNDARFQAMY-TSHLFNLDP 775
H + +++ K+++Q K K+ E++ E + D Q + + + L P
Sbjct: 5150 HIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKP 5209
Query: 776 SDPNFKKTKAM----EKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSML 831
+ T + ++ + + E ++ +A K+ E+E + S+ +I A L
Sbjct: 5210 EEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFL 5269
Query: 832 IKSI 835
+ +I
Sbjct: 5270 MDTI 5273
Score = 34.7 bits (78), Expect = 0.38
Identities = 65/356 (18%), Positives = 139/356 (39%), Gaps = 50/356 (14%)
Query: 494 PKYFTSAAMGTSTVEITWDET----DHERITMLNRKFKKEELLDMDFQAYLASSSEDEEE 549
PK F + G E E + E + ++ + EE ++ FQ ED +
Sbjct: 4657 PKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDS 4716
Query: 550 IEEELQGDDGVNVEE-------DGKTKKSQKDDE------------------EQIAKYRQ 584
+ D+ + + E DG+ ++ ++DDE E+ K +
Sbjct: 4717 KSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDE 4776
Query: 585 LLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKR 644
L ++E+ +E D + E + PG+ E E+V D L +K ++ K+
Sbjct: 4777 RLWGDDDEEEDEEEEDNKTE-ETGPGMDEEDSELVAK----DDNLDSGNSNKDKSQQDKK 4831
Query: 645 LKRKQKALAEEA--SEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIE 702
+ K++A A++ E+++ +D D Y EV N++ V + P++
Sbjct: 4832 -EEKEEAEADDGGQGEDKINEQIDERD-YDENEVDPYHGNQEKVPEPEALDLPDD----- 4884
Query: 703 RQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARF 762
L + ED++ + + + E L K+K + + + E + N+++
Sbjct: 4885 -------LNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQS 4937
Query: 763 QAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKE 818
D ++ + + + A+ E +E Q++++K+ E ++E
Sbjct: 4938 PQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEE 4993
Score = 33.5 bits (75), Expect = 0.86
Identities = 74/406 (18%), Positives = 150/406 (36%), Gaps = 55/406 (13%)
Query: 54 DKRGRPISHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEK 113
+K P + +DL + + + E+ + + +IK+K + E + + E
Sbjct: 4871 EKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETET 4930
Query: 114 KKETKKANHKGSENKTDLDNSIGIKKMKTSCKFKI-DSNISPKKDSKEFTQKNKKEKKNI 172
+ ++ + E ++ D + G ++M T + D+ P++ S+E Q +++ K
Sbjct: 4931 DQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEA 4990
Query: 173 VQHTTDS-------SLEEKQRTLDSGTSEIV-----KSPRIECSKTRREMQSVVQLI--- 217
+ ++ +E++ DS T E V + C +T E Q +
Sbjct: 4991 DEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELA 5050
Query: 218 --MTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASG--DDDGSE 273
G E G A +S ++++ S + + S R G D++ S
Sbjct: 5051 GAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSM 5110
Query: 274 DDEEE---------DEDEEEDED---------EDSEDDDKSDSGPDLARGKGNIETSSED 315
D E D D ++ ED++ + G D A + +S++
Sbjct: 5111 GDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSD-AYDAQTYDVASKE 5169
Query: 316 EDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLALFNSFKPK 375
+ +A ++SG + E++ +E A D ++LK +++ K
Sbjct: 5170 QQQSA----KDSGKDQEEEEIEDTLMDTEEQEEFKAA---DVEQLKPEEI---------K 5213
Query: 376 GGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSRE 421
G + E + +K E+ Q P + E EK SRE
Sbjct: 5214 SGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRE 5259
Score = 32.7 bits (73), Expect = 1.5
Identities = 57/278 (20%), Positives = 110/278 (39%), Gaps = 41/278 (14%)
Query: 570 KSQKDDEEQIAKYRQLLQVIQEKEKKGKEN-DMEMEIKWVPG----------------LK 612
+ KD +QI Q+ Q+ ++K KE+ D + +IK L+
Sbjct: 4684 EGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELE 4743
Query: 613 ESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYF 672
E E+ K+ EG D L L ++ K +R EE EEE + + P
Sbjct: 4744 EQEEDDEKSDSEGGD-LDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGM 4802
Query: 673 AEEVKQI---GINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIV 729
EE ++ N S S KD + +++ E E +A D+ + N+ +
Sbjct: 4803 DEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEA---------DDGGQGEDKINEQI 4853
Query: 730 EHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKI 789
+ ++ + + +E + + +++ D NLD D N + E+
Sbjct: 4854 DERDYDENEVDPYHGNQEKVPEPEALDLPDD----------LNLDSEDKNGGEDTDNEEG 4903
Query: 790 LEEKARQ-RERKEQELTQAIKKKESEIEKESQRKSIDP 826
EE + +E+ E+ +A ++ E+E ++ + +P
Sbjct: 4904 EEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEP 4941
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 62.4 bits (150), Expect = 2e-09
Identities = 72/285 (25%), Positives = 122/285 (42%), Gaps = 23/285 (8%)
Query: 61 SHSTTEDLKRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKA 120
S E + F S S + S ++SQ I + QT+ + + + + A
Sbjct: 1731 SEGPVEHVPVFGSTSGSVRSTSPNVQPSISQP-ILTVQQQTQATAFVQPTQQSHPQIEPA 1789
Query: 121 NHKGSENKTDLDNSIGIKKMKTSCKF-----KIDSNISPKKDSKEFTQKNKKEKKNIVQH 175
N + S N ++ S +++ TS S+ PK+ +E + +
Sbjct: 1790 NQELSSNIVEVVQSSPVERPSTSTAVFGTVSATPSSSLPKRTREEEEDSTIEASDQVSDD 1849
Query: 176 TTDSSLEEKQRTLDS-GTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMC 234
T + L +K +++ GT E V + T E+++ V ++DS G E T G+
Sbjct: 1850 TVEMPLPKKLKSVTPVGTEEEVMAEE----STDGEVETQVYNQDSQDSIG-EGVTQGDYT 1904
Query: 235 DKDALEEDSESVS-EIGSDEESENEITSV--GRASGDD-------DGSEDDEEED-EDEE 283
+ EE S+S+ ++G + + TS G+ GDD D EDD+E D E E+
Sbjct: 1905 PMEDSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHED 1964
Query: 284 EDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTADLFPEESG 328
+EDE+ +DDD+ D+G N T S D +D + E G
Sbjct: 1965 YEEDEEDDDDDEDDTGMGDEGEDSNEGTGSADGNDGYEADDAEGG 2009
Score = 42.7 bits (99), Expect = 0.001
Identities = 66/333 (19%), Positives = 149/333 (44%), Gaps = 51/333 (15%)
Query: 522 LNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAK 581
L++ K+ + Q +L + ++++E+E+ +E+ G+ +K ++ + ++
Sbjct: 310 LHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEM-------LEKIGRLEKELENANDLLSA 362
Query: 582 YRQLLQVIQEKEKKGKENDMEMEIKWV-PGLKESAEEMVKNKLEGKDKLTPWEQFLEKKK 640
++ ++ E+E K V PG+K + E+ +E +D+L L +K
Sbjct: 363 TKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLT--ELYNAYVETQDQL------LLEKL 414
Query: 641 EKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIE 700
E KR+ + +E+ +V+ P + ++ +K+V S ++
Sbjct: 415 ENKRINKYL---------DEIVKEVEAKAPILKRQREEYERAQKAVASLS--------VK 457
Query: 701 IERQKAEMALLMMDEDEDSKKHF-----NYNKIVEHQNLSKKKKKQLMKKKE-----LIE 750
+E+ E+ L D D+ +K+ N ++ ++LS++ + LM+ +E +I
Sbjct: 458 LEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIR 517
Query: 751 DDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKK 810
D+ + + + + + HL + + ++ + + L E RER+EQE T + K
Sbjct: 518 DEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSS-KI 576
Query: 811 KESEIEKESQRKSIDPALSMLIKSIKTKTEQFQ 843
E +++ ES AL+ L + K++ Q Q
Sbjct: 577 TELQLKLES-------ALTELEQLRKSRQHQMQ 602
Score = 41.2 bits (95), Expect = 0.004
Identities = 45/215 (20%), Positives = 85/215 (39%), Gaps = 39/215 (18%)
Query: 168 EKKNIVQHTTDSSLE------EKQRTLDSGTSEIVKSPRIECSKTRREMQSVV------Q 215
E++ + + +TD +E + Q ++ G ++ +P + +T + +Q + Q
Sbjct: 1868 EEEVMAEESTDGEVETQVYNQDSQDSIGEGVTQGDYTPMEDSEETSQSLQIDLGPLQSDQ 1927
Query: 216 LIMTRDSDGYENSTDGEMCDKDALEEDS-------ESVSEIGSDEESENEITSVG----- 263
T DG D + D D EED E E D++ + + T +G
Sbjct: 1928 QTTTSSQDGQGKGDDVIVIDSDDEEEDDDENDGEHEDYEEDEEDDDDDEDDTGMGDEGED 1987
Query: 264 --RASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDTAD 321
+G DG++ E +D + + D +E ++ + G+GN + +
Sbjct: 1988 SNEGTGSADGNDGYEADDAEGGDGTDPGTETEE------SMGGGEGNHRAADSQNSGEGN 2041
Query: 322 LFPEESGF-EHAWRE------LDKDAPRADEITRR 349
ES F + RE ++ APRA + RR
Sbjct: 2042 TGAAESSFSQEVSREQQPSSASERQAPRAPQSPRR 2076
Score = 38.9 bits (89), Expect = 0.020
Identities = 74/371 (19%), Positives = 153/371 (41%), Gaps = 43/371 (11%)
Query: 488 NLTAYKPKYFTSAAMGTSTVEITWDETDHER--ITMLNRKFKKEELLDMDFQAYLASSSE 545
+L + K T + E+ D + R IT L+ + +K + + + ++
Sbjct: 706 DLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQ 765
Query: 546 DEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEI 605
D E+L + V E K K+ K E ++++ R+ L E++G +N + +
Sbjct: 766 DLRGANEKLAVAE-VRAENLKKEKEMLKLSEVRLSQQRESLLA----EQRG-QNLLLTNL 819
Query: 606 KWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDV 665
+ + G+ E +E K +L Q + + E LK+K + E+ DV
Sbjct: 820 QTIQGILERSETETKQRLSS--------QIEKLEHEISHLKKKLENEVEQRHTLTRNLDV 871
Query: 666 DLNDPYFAEEVK-QIGINKKSV-KSAKD--GTSPEEEIEIERQKAEMALLMMDEDEDSKK 721
L D + + + +N K + K+A+ T + +E Q A + + + S K
Sbjct: 872 QLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNK 931
Query: 722 HFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFK 781
+ + +V ++++ L ++ + + E ++QAM TS + +
Sbjct: 932 E-DVDDLVSQLRQTEEQVNDLKERLKTSTSNVE------QYQAMVTS-------LEESLN 977
Query: 782 KTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQR---------KSIDPALSMLI 832
K K + + + + R ++ E ++KK E+EKE Q +S++ LS L
Sbjct: 978 KEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELK 1037
Query: 833 KSIKTKTEQFQ 843
K++ + + Q
Sbjct: 1038 KTLSSVQNEVQ 1048
Score = 37.0 bits (84), Expect = 0.077
Identities = 61/282 (21%), Positives = 117/282 (41%), Gaps = 46/282 (16%)
Query: 576 EEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQF 635
+EQ++K + Q ++E +K + +E + W E E M+K+++ K +
Sbjct: 1100 KEQVSKMASVRQHLEETTQKAESQLLECKASW-----EERERMLKDEVS---KCVCRCED 1151
Query: 636 LEKKKE---KKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDG 692
LEK+ + K K +A + P +V L++ ++E QI + ++ K+
Sbjct: 1152 LEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQE--QILEILRFIRREKEI 1209
Query: 693 TSPEEEI-EIE----RQKAEMALLMMDEDEDS------KKHFNYNKIVEHQNLSKKKK-- 739
E+ ++E RQ+ E+ + E +DS K + +H+ L KK +
Sbjct: 1210 AETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETM 1269
Query: 740 -------KQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAM----EK 788
K L ++KE +E D + R + + L ++ + M +K
Sbjct: 1270 NVVMETNKMLREEKERLEQDLQQMQAKVRKLEL---DILPLQEANAELSEKSGMLQAEKK 1326
Query: 789 ILEEKARQRERKEQELTQAIKKKESE------IEKESQRKSI 824
+LEE ++ + + Q L K ++E EKE K I
Sbjct: 1327 LLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRI 1368
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 61.6 bits (148), Expect = 3e-09
Identities = 77/331 (23%), Positives = 128/331 (38%), Gaps = 44/331 (13%)
Query: 21 RFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGR-PISHSTTEDLKRFYDLSDSDS 79
R W + +K K R A+ + K ++RG+ P S E++ + + D +
Sbjct: 406 RMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLA 465
Query: 80 NLSGEDSKALSQKKI-------KKKKTQTKKEIDSKNLVEKK-----------KETKKAN 121
+ KAL ++ K+K KK + + E++ +KK
Sbjct: 466 RFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMK 525
Query: 122 HKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDS--------KEFTQKNKKEKKNIV 173
+G K ++ G +K + N P K+ + +Q K+ K +
Sbjct: 526 FQGEPKKPPMN---GYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLA 582
Query: 174 QHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEM 233
EE+Q+ VKS + +E S + MT+ S+ +
Sbjct: 583 --------EEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTL 634
Query: 234 CDKDALEEDSESVSEIGSDEESENEITSVGRASGD----DDGSEDDEEEDEDEEEDEDED 289
K EED E E DE+ E E G +S D + S +DE ED DE E++DED
Sbjct: 635 QSKSESEEDDEE-DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693
Query: 290 SEDDDKSDSGPD-LARGKGNIETSSEDEDDT 319
+DD+ D D + G + +SS D D+
Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 724
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 61.6 bits (148), Expect = 3e-09
Identities = 77/331 (23%), Positives = 128/331 (38%), Gaps = 44/331 (13%)
Query: 21 RFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGR-PISHSTTEDLKRFYDLSDSDS 79
R W + +K K R A+ + K ++RG+ P S E++ + + D +
Sbjct: 406 RMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLA 465
Query: 80 NLSGEDSKALSQKKI-------KKKKTQTKKEIDSKNLVEKK-----------KETKKAN 121
+ KAL ++ K+K KK + + E++ +KK
Sbjct: 466 RFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMK 525
Query: 122 HKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDS--------KEFTQKNKKEKKNIV 173
+G K ++ G +K + N P K+ + +Q K+ K +
Sbjct: 526 FQGEPKKPPMN---GYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLA 582
Query: 174 QHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEM 233
EE+Q+ VKS + +E S + MT+ S+ +
Sbjct: 583 --------EEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTL 634
Query: 234 CDKDALEEDSESVSEIGSDEESENEITSVGRASGD----DDGSEDDEEEDEDEEEDEDED 289
K EED E E DE+ E E G +S D + S +DE ED DE E++DED
Sbjct: 635 QSKSESEEDDEE-DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 693
Query: 290 SEDDDKSDSGPD-LARGKGNIETSSEDEDDT 319
+DD+ D D + G + +SS D D+
Sbjct: 694 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 724
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 61.6 bits (148), Expect = 3e-09
Identities = 77/331 (23%), Positives = 128/331 (38%), Gaps = 44/331 (13%)
Query: 21 RFWEMPEKDRKVKIDKRFRAMFHDKKFKLNYAVDKRGR-PISHSTTEDLKRFYDLSDSDS 79
R W + +K K R A+ + K ++RG+ P S E++ + + D +
Sbjct: 443 RMWNDLSEKKKAKYKAREAALKAQSERKPGGEREERGKLPESPKRAEEIWQQSVIGDYLA 502
Query: 80 NLSGEDSKALSQKKI-------KKKKTQTKKEIDSKNLVEKK-----------KETKKAN 121
+ KAL ++ K+K KK + + E++ +KK
Sbjct: 503 RFKNDRVKALKAMEMTWNNMEKKEKLMWIKKAAEDQKRYERELSEMRAPPAATNSSKKMK 562
Query: 122 HKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDS--------KEFTQKNKKEKKNIV 173
+G K ++ G +K + N P K+ + +Q K+ K +
Sbjct: 563 FQGEPKKPPMN---GYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLA 619
Query: 174 QHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEM 233
EE+Q+ VKS + +E S + MT+ S+ +
Sbjct: 620 --------EEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTL 671
Query: 234 CDKDALEEDSESVSEIGSDEESENEITSVGRASGD----DDGSEDDEEEDEDEEEDEDED 289
K EED E E DE+ E E G +S D + S +DE ED DE E++DED
Sbjct: 672 QSKSESEEDDEE-DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDED 730
Query: 290 SEDDDKSDSGPD-LARGKGNIETSSEDEDDT 319
+DD+ D D + G + +SS D D+
Sbjct: 731 EDDDEDDDEDEDNESEGSSSSSSSSGDSSDS 761
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 61.2 bits (147), Expect = 4e-09
Identities = 166/875 (18%), Positives = 348/875 (39%), Gaps = 144/875 (16%)
Query: 74 LSDSDSNLSGEDSKALSQKKIKKK--------KTQTKKEIDSKNLVEKKKETKKANHKG- 124
+SD +NL+ E+ KA + K+K K + + KKE S+ +EK K + +
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Query: 125 SENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEK 184
E DL I KM+ + K + + + + E QKN KK + + +
Sbjct: 1068 HEQIADLQAQIAELKMQLA-KKEEELQAALARLDDEIAQKNNALKK---IRELEGHISDL 1123
Query: 185 QRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSE 244
Q LDS ++ R + K +R++ ++ + T D D A +++
Sbjct: 1124 QEDLDS-----ERAARNKAEKQKRDLGEELEALKTELED---------TLDSTATQQELR 1169
Query: 245 SVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLAR 304
+ + E E+T + +A ++ S E + +E + ++ ++ R
Sbjct: 1170 A--------KREQEVTVLKKALDEETRS----HEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 305 GKGNIETSSED-EDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAK 363
K N++ + + E + ADL E A +E++ + + + L D +R +A+
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 364 ---DLLALFNSFKPKGGVIFSVKIYPSEFGKE-RMKEEQVQGPVELL------------- 406
+ L N + G++ + + K+ Q+Q ELL
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337
Query: 407 --------SIPEDAPEKDWTSREKLRDY----------QFKRLKYYYAVVDCDSPETASK 448
+ +D +++ +++ L + K+L+ + + V+ E +
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA-LEEGKKR 1396
Query: 449 IYEDCDGL--EFESSCSFID--------LRFIPDDITFD-DEPKDVASEVNLTAYKPKYF 497
++ + L ++E + D L+ DD+ D D + + S NL + K+
Sbjct: 1397 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS--NLEKKQRKFD 1454
Query: 498 TSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIE------ 551
A + DE D + +++E + L + E +EE+E
Sbjct: 1455 QLLAEEKNISSKYADERDR-----AEAEAREKETKALSLARALEEALEAKEELERTNKML 1509
Query: 552 ----EEL---QGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
E+L + D G NV E +KS++ E Q+ + + L+ ++++ + ++ + +E
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE 1566
Query: 605 IKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASE------ 658
+ + ++ + ++K ++ L + + + +RKQ+ALA A +
Sbjct: 1567 VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1626
Query: 659 EELPSDVDLNDPYFAEEVKQIGINKKSVK----SAKDGTSPEEEI-------EIERQKAE 707
++L D E +KQ+ + +K +D + +EI E + + E
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Query: 708 MALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYT 767
L+ + ED + + +E + L+++ L + L ++ + A+ +
Sbjct: 1687 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE 1746
Query: 768 SHLFNLDP-SDPNFKKTKAMEKILEEKARQR-------------ERKEQELTQAIKKKES 813
N++ SD K T+ E++ E A +R ER+ +EL + + E
Sbjct: 1747 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG 1806
Query: 814 EIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
+ +S+ KS AL I ++ + EQ +AR+KQ
Sbjct: 1807 AV--KSKFKSTIAALEAKIAQLEEQVEQ-EAREKQ 1838
Score = 58.9 bits (141), Expect = 2e-08
Identities = 169/869 (19%), Positives = 335/869 (38%), Gaps = 146/869 (16%)
Query: 68 LKRFYDLSDSDSNLSGE-DSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSE 126
LK+ +L S+L + DS+ ++ K +K+K +E+++ L + ++T + E
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA--LKTELEDTLDSTATQQE 1167
Query: 127 NKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTD-----SSL 181
+ + + + K K + S + +E QK+ + + + + ++L
Sbjct: 1168 LRAKREQEVTVLK-----KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 182 EEKQRTLDSGTSEIVKSPRI------ECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCD 235
++ ++TL+ +++ R+ E ++++++ VQ + ++ SDG E+ D
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG--ERARAELND 1280
Query: 236 K-DALEEDSESVSEIGSDEESE-----NEITSVGRASGDDDGSEDDEEEDE--------- 280
K L+ + ESV+ + ++ E + ++ S+ D +E +
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 281 -DEEEDEDEDSEDDDK-----------------SDSGPDLARGKGNIETSSED----EDD 318
+EE + +D D++ SDS L +E E + +
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 319 TADLFPEESGFEHAWRELDKDAPR---------ADEITRRLAVCNMDWDRLKAKDLLALF 369
+L + A+ +L+K R D +R V N++ + K LLA
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 370 NSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQFK 429
+ K Y E ++R + E + + LS+ A E+ ++E+L K
Sbjct: 1461 KNISSK---------YADE--RDRAEAEAREKETKALSLAR-ALEEALEAKEELERTN-K 1507
Query: 430 RLKYYYAVVDCDSPETASKIYE---DCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASE 486
LK + + ++E LE + L + D++ ++ K + E
Sbjct: 1508 MLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-LRLE 1566
Query: 487 VNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKK--EELLDMDFQAYLASSS 544
VN+ A K ++ DE + E+ L R+ + EL D Q LA+++
Sbjct: 1567 VNMQALKGQFERDLQAR--------DEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 545 EDEEE---IEEELQGDDGVNVEEDG---------KTKKSQKDDEEQIAKYRQLLQVIQEK 592
+ + E + ELQ D + E+ + K Q++ E+ A ++ +E
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Query: 593 EKKGK--ENDM----------EMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKK 640
EKK K E D+ E K KE E + + L G++ L EK++
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD-----EKRR 1733
Query: 641 EKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIE 700
+ R+ + ++ L EE E SD AE++ ++S + +
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ---- 1789
Query: 701 IERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVN-D 759
+ERQ E+ +K+ E + K K K + E E V +
Sbjct: 1790 LERQNKELR----------------SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1833
Query: 760 ARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKES 819
AR + T L D E+ + E+ +++ K + +K++ E E+ES
Sbjct: 1834 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1893
Query: 820 QRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
QR I+ L + + TE +A ++
Sbjct: 1894 QR--INANRRKLQRELDEATESNEAMGRE 1920
Score = 42.7 bits (99), Expect = 0.001
Identities = 74/371 (19%), Positives = 149/371 (40%), Gaps = 64/371 (17%)
Query: 513 ETDHERIT----MLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKT 568
E H ++T +L + + E L + + + ++E+EE L + EE+ +
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Query: 569 KKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDK 628
++ Q + ++ + L + ++E+E ++ +E K +AE +K KLE
Sbjct: 939 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE---------KVTAEAKIK-KLE---- 984
Query: 629 LTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKS 688
++ L + +L +++K L E S DL EE K + K +K+
Sbjct: 985 ----DEILVMDDQNNKLSKERKLLEERIS--------DLTTNLAEEEEKAKNLTK--LKN 1030
Query: 689 AKDGTSPEEEIEIER-QKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKE 747
+ E E+ +++ +K+ L + + + +I + Q + K QL KK+E
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 748 -------LIEDDFEVNVNDARFQAMYTSHLFNL--DPSDPNFKKTKA------------- 785
++D+ N + H+ +L D + KA
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 786 ----MEKILEEKARQRE---RKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTK 838
+E L+ A Q+E ++EQE+T + KK + E S + ++++
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVT--VLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 839 TEQFQARKKQK 849
TEQ + K+ K
Sbjct: 1209 TEQLEQFKRAK 1219
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 61.2 bits (147), Expect = 4e-09
Identities = 166/875 (18%), Positives = 348/875 (39%), Gaps = 144/875 (16%)
Query: 74 LSDSDSNLSGEDSKALSQKKIKKK--------KTQTKKEIDSKNLVEKKKETKKANHKG- 124
+SD +NL+ E+ KA + K+K K + + KKE S+ +EK K + +
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074
Query: 125 SENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEK 184
E DL I KM+ + K + + + + E QKN KK + + +
Sbjct: 1075 HEQIADLQAQIAELKMQLA-KKEEELQAALARLDDEIAQKNNALKK---IRELEGHISDL 1130
Query: 185 QRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSE 244
Q LDS ++ R + K +R++ ++ + T D D A +++
Sbjct: 1131 QEDLDS-----ERAARNKAEKQKRDLGEELEALKTELED---------TLDSTATQQELR 1176
Query: 245 SVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLAR 304
+ + E E+T + +A ++ S E + +E + ++ ++ R
Sbjct: 1177 A--------KREQEVTVLKKALDEETRS----HEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 305 GKGNIETSSED-EDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAK 363
K N++ + + E + ADL E A +E++ + + + L D +R +A+
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 364 ---DLLALFNSFKPKGGVIFSVKIYPSEFGKE-RMKEEQVQGPVELL------------- 406
+ L N + G++ + + K+ Q+Q ELL
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344
Query: 407 --------SIPEDAPEKDWTSREKLRDY----------QFKRLKYYYAVVDCDSPETASK 448
+ +D +++ +++ L + K+L+ + + V+ E +
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA-LEEGKKR 1403
Query: 449 IYEDCDGL--EFESSCSFID--------LRFIPDDITFD-DEPKDVASEVNLTAYKPKYF 497
++ + L ++E + D L+ DD+ D D + + S NL + K+
Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS--NLEKKQRKFD 1461
Query: 498 TSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIE------ 551
A + DE D + +++E + L + E +EE+E
Sbjct: 1462 QLLAEEKNISSKYADERDR-----AEAEAREKETKALSLARALEEALEAKEELERTNKML 1516
Query: 552 ----EEL---QGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
E+L + D G NV E +KS++ E Q+ + + L+ ++++ + ++ + +E
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE 1573
Query: 605 IKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASE------ 658
+ + ++ + ++K ++ L + + + +RKQ+ALA A +
Sbjct: 1574 VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1633
Query: 659 EELPSDVDLNDPYFAEEVKQIGINKKSVK----SAKDGTSPEEEI-------EIERQKAE 707
++L D E +KQ+ + +K +D + +EI E + + E
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Query: 708 MALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYT 767
L+ + ED + + +E + L+++ L + L ++ + A+ +
Sbjct: 1694 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE 1753
Query: 768 SHLFNLDP-SDPNFKKTKAMEKILEEKARQR-------------ERKEQELTQAIKKKES 813
N++ SD K T+ E++ E A +R ER+ +EL + + E
Sbjct: 1754 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG 1813
Query: 814 EIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
+ +S+ KS AL I ++ + EQ +AR+KQ
Sbjct: 1814 AV--KSKFKSTIAALEAKIAQLEEQVEQ-EAREKQ 1845
Score = 58.9 bits (141), Expect = 2e-08
Identities = 169/869 (19%), Positives = 335/869 (38%), Gaps = 146/869 (16%)
Query: 68 LKRFYDLSDSDSNLSGE-DSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSE 126
LK+ +L S+L + DS+ ++ K +K+K +E+++ L + ++T + E
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA--LKTELEDTLDSTATQQE 1174
Query: 127 NKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTD-----SSL 181
+ + + + K K + S + +E QK+ + + + + ++L
Sbjct: 1175 LRAKREQEVTVLK-----KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1229
Query: 182 EEKQRTLDSGTSEIVKSPRI------ECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCD 235
++ ++TL+ +++ R+ E ++++++ VQ + ++ SDG E+ D
Sbjct: 1230 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG--ERARAELND 1287
Query: 236 K-DALEEDSESVSEIGSDEESE-----NEITSVGRASGDDDGSEDDEEEDE--------- 280
K L+ + ESV+ + ++ E + ++ S+ D +E +
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347
Query: 281 -DEEEDEDEDSEDDDK-----------------SDSGPDLARGKGNIETSSED----EDD 318
+EE + +D D++ SDS L +E E + +
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 319 TADLFPEESGFEHAWRELDKDAPR---------ADEITRRLAVCNMDWDRLKAKDLLALF 369
+L + A+ +L+K R D +R V N++ + K LLA
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 370 NSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQFK 429
+ K Y E ++R + E + + LS+ A E+ ++E+L K
Sbjct: 1468 KNISSK---------YADE--RDRAEAEAREKETKALSLAR-ALEEALEAKEELERTN-K 1514
Query: 430 RLKYYYAVVDCDSPETASKIYE---DCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASE 486
LK + + ++E LE + L + D++ ++ K + E
Sbjct: 1515 MLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-LRLE 1573
Query: 487 VNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKK--EELLDMDFQAYLASSS 544
VN+ A K ++ DE + E+ L R+ + EL D Q LA+++
Sbjct: 1574 VNMQALKGQFERDLQAR--------DEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625
Query: 545 EDEEE---IEEELQGDDGVNVEEDG---------KTKKSQKDDEEQIAKYRQLLQVIQEK 592
+ + E + ELQ D + E+ + K Q++ E+ A ++ +E
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Query: 593 EKKGK--ENDM----------EMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKK 640
EKK K E D+ E K KE E + + L G++ L EK++
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD-----EKRR 1740
Query: 641 EKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIE 700
+ R+ + ++ L EE E SD AE++ ++S + +
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ---- 1796
Query: 701 IERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVN-D 759
+ERQ E+ +K+ E + K K K + E E V +
Sbjct: 1797 LERQNKELR----------------SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1840
Query: 760 ARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKES 819
AR + T L D E+ + E+ +++ K + +K++ E E+ES
Sbjct: 1841 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1900
Query: 820 QRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
QR I+ L + + TE +A ++
Sbjct: 1901 QR--INANRRKLQRELDEATESNEAMGRE 1927
Score = 42.7 bits (99), Expect = 0.001
Identities = 74/371 (19%), Positives = 149/371 (40%), Gaps = 64/371 (17%)
Query: 513 ETDHERIT----MLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKT 568
E H ++T +L + + E L + + + ++E+EE L + EE+ +
Sbjct: 886 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 945
Query: 569 KKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDK 628
++ Q + ++ + L + ++E+E ++ +E K +AE +K KLE
Sbjct: 946 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE---------KVTAEAKIK-KLE---- 991
Query: 629 LTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKS 688
++ L + +L +++K L E S DL EE K + K +K+
Sbjct: 992 ----DEILVMDDQNNKLSKERKLLEERIS--------DLTTNLAEEEEKAKNLTK--LKN 1037
Query: 689 AKDGTSPEEEIEIER-QKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKE 747
+ E E+ +++ +K+ L + + + +I + Q + K QL KK+E
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 748 -------LIEDDFEVNVNDARFQAMYTSHLFNL--DPSDPNFKKTKA------------- 785
++D+ N + H+ +L D + KA
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 786 ----MEKILEEKARQRE---RKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTK 838
+E L+ A Q+E ++EQE+T + KK + E S + ++++
Sbjct: 1158 LKTELEDTLDSTATQQELRAKREQEVT--VLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 839 TEQFQARKKQK 849
TEQ + K+ K
Sbjct: 1216 TEQLEQFKRAK 1226
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 61.2 bits (147), Expect = 4e-09
Identities = 166/875 (18%), Positives = 348/875 (39%), Gaps = 144/875 (16%)
Query: 74 LSDSDSNLSGEDSKALSQKKIKKK--------KTQTKKEIDSKNLVEKKKETKKANHKG- 124
+SD +NL+ E+ KA + K+K K + + KKE S+ +EK K + +
Sbjct: 1015 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1074
Query: 125 SENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEK 184
E DL I KM+ + K + + + + E QKN KK + + +
Sbjct: 1075 HEQIADLQAQIAELKMQLA-KKEEELQAALARLDDEIAQKNNALKK---IRELEGHISDL 1130
Query: 185 QRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSE 244
Q LDS ++ R + K +R++ ++ + T D D A +++
Sbjct: 1131 QEDLDS-----ERAARNKAEKQKRDLGEELEALKTELED---------TLDSTATQQELR 1176
Query: 245 SVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLAR 304
+ + E E+T + +A ++ S E + +E + ++ ++ R
Sbjct: 1177 A--------KREQEVTVLKKALDEETRS----HEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 305 GKGNIETSSED-EDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAK 363
K N++ + + E + ADL E A +E++ + + + L D +R +A+
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 364 ---DLLALFNSFKPKGGVIFSVKIYPSEFGKE-RMKEEQVQGPVELL------------- 406
+ L N + G++ + + K+ Q+Q ELL
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1344
Query: 407 --------SIPEDAPEKDWTSREKLRDY----------QFKRLKYYYAVVDCDSPETASK 448
+ +D +++ +++ L + K+L+ + + V+ E +
Sbjct: 1345 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA-LEEGKKR 1403
Query: 449 IYEDCDGL--EFESSCSFID--------LRFIPDDITFD-DEPKDVASEVNLTAYKPKYF 497
++ + L ++E + D L+ DD+ D D + + S NL + K+
Sbjct: 1404 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS--NLEKKQRKFD 1461
Query: 498 TSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIE------ 551
A + DE D + +++E + L + E +EE+E
Sbjct: 1462 QLLAEEKNISSKYADERDR-----AEAEAREKETKALSLARALEEALEAKEELERTNKML 1516
Query: 552 ----EEL---QGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
E+L + D G NV E +KS++ E Q+ + + L+ ++++ + ++ + +E
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE 1573
Query: 605 IKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASE------ 658
+ + ++ + ++K ++ L + + + +RKQ+ALA A +
Sbjct: 1574 VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1633
Query: 659 EELPSDVDLNDPYFAEEVKQIGINKKSVK----SAKDGTSPEEEI-------EIERQKAE 707
++L D E +KQ+ + +K +D + +EI E + + E
Sbjct: 1634 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1693
Query: 708 MALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYT 767
L+ + ED + + +E + L+++ L + L ++ + A+ +
Sbjct: 1694 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE 1753
Query: 768 SHLFNLDP-SDPNFKKTKAMEKILEEKARQR-------------ERKEQELTQAIKKKES 813
N++ SD K T+ E++ E A +R ER+ +EL + + E
Sbjct: 1754 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG 1813
Query: 814 EIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
+ +S+ KS AL I ++ + EQ +AR+KQ
Sbjct: 1814 AV--KSKFKSTIAALEAKIAQLEEQVEQ-EAREKQ 1845
Score = 58.9 bits (141), Expect = 2e-08
Identities = 169/869 (19%), Positives = 335/869 (38%), Gaps = 146/869 (16%)
Query: 68 LKRFYDLSDSDSNLSGE-DSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSE 126
LK+ +L S+L + DS+ ++ K +K+K +E+++ L + ++T + E
Sbjct: 1117 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA--LKTELEDTLDSTATQQE 1174
Query: 127 NKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTD-----SSL 181
+ + + + K K + S + +E QK+ + + + + ++L
Sbjct: 1175 LRAKREQEVTVLK-----KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1229
Query: 182 EEKQRTLDSGTSEIVKSPRI------ECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCD 235
++ ++TL+ +++ R+ E ++++++ VQ + ++ SDG E+ D
Sbjct: 1230 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG--ERARAELND 1287
Query: 236 K-DALEEDSESVSEIGSDEESE-----NEITSVGRASGDDDGSEDDEEEDE--------- 280
K L+ + ESV+ + ++ E + ++ S+ D +E +
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347
Query: 281 -DEEEDEDEDSEDDDK-----------------SDSGPDLARGKGNIETSSED----EDD 318
+EE + +D D++ SDS L +E E + +
Sbjct: 1348 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1407
Query: 319 TADLFPEESGFEHAWRELDKDAPR---------ADEITRRLAVCNMDWDRLKAKDLLALF 369
+L + A+ +L+K R D +R V N++ + K LLA
Sbjct: 1408 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1467
Query: 370 NSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQFK 429
+ K Y E ++R + E + + LS+ A E+ ++E+L K
Sbjct: 1468 KNISSK---------YADE--RDRAEAEAREKETKALSLAR-ALEEALEAKEELERTN-K 1514
Query: 430 RLKYYYAVVDCDSPETASKIYE---DCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASE 486
LK + + ++E LE + L + D++ ++ K + E
Sbjct: 1515 MLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-LRLE 1573
Query: 487 VNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKK--EELLDMDFQAYLASSS 544
VN+ A K ++ DE + E+ L R+ + EL D Q LA+++
Sbjct: 1574 VNMQALKGQFERDLQAR--------DEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625
Query: 545 EDEEE---IEEELQGDDGVNVEEDG---------KTKKSQKDDEEQIAKYRQLLQVIQEK 592
+ + E + ELQ D + E+ + K Q++ E+ A ++ +E
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Query: 593 EKKGK--ENDM----------EMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKK 640
EKK K E D+ E K KE E + + L G++ L EK++
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD-----EKRR 1740
Query: 641 EKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIE 700
+ R+ + ++ L EE E SD AE++ ++S + +
Sbjct: 1741 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ---- 1796
Query: 701 IERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVN-D 759
+ERQ E+ +K+ E + K K K + E E V +
Sbjct: 1797 LERQNKELR----------------SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1840
Query: 760 ARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKES 819
AR + T L D E+ + E+ +++ K + +K++ E E+ES
Sbjct: 1841 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1900
Query: 820 QRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
QR I+ L + + TE +A ++
Sbjct: 1901 QR--INANRRKLQRELDEATESNEAMGRE 1927
Score = 42.7 bits (99), Expect = 0.001
Identities = 74/371 (19%), Positives = 149/371 (40%), Gaps = 64/371 (17%)
Query: 513 ETDHERIT----MLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKT 568
E H ++T +L + + E L + + + ++E+EE L + EE+ +
Sbjct: 886 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 945
Query: 569 KKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDK 628
++ Q + ++ + L + ++E+E ++ +E K +AE +K KLE
Sbjct: 946 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE---------KVTAEAKIK-KLE---- 991
Query: 629 LTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKS 688
++ L + +L +++K L E S DL EE K + K +K+
Sbjct: 992 ----DEILVMDDQNNKLSKERKLLEERIS--------DLTTNLAEEEEKAKNLTK--LKN 1037
Query: 689 AKDGTSPEEEIEIER-QKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKE 747
+ E E+ +++ +K+ L + + + +I + Q + K QL KK+E
Sbjct: 1038 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1097
Query: 748 -------LIEDDFEVNVNDARFQAMYTSHLFNL--DPSDPNFKKTKA------------- 785
++D+ N + H+ +L D + KA
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1157
Query: 786 ----MEKILEEKARQRE---RKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTK 838
+E L+ A Q+E ++EQE+T + KK + E S + ++++
Sbjct: 1158 LKTELEDTLDSTATQQELRAKREQEVT--VLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1215
Query: 839 TEQFQARKKQK 849
TEQ + K+ K
Sbjct: 1216 TEQLEQFKRAK 1226
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 61.2 bits (147), Expect = 4e-09
Identities = 166/875 (18%), Positives = 348/875 (39%), Gaps = 144/875 (16%)
Query: 74 LSDSDSNLSGEDSKALSQKKIKKK--------KTQTKKEIDSKNLVEKKKETKKANHKG- 124
+SD +NL+ E+ KA + K+K K + + KKE S+ +EK K + +
Sbjct: 1008 ISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDF 1067
Query: 125 SENKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEK 184
E DL I KM+ + K + + + + E QKN KK + + +
Sbjct: 1068 HEQIADLQAQIAELKMQLA-KKEEELQAALARLDDEIAQKNNALKK---IRELEGHISDL 1123
Query: 185 QRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSE 244
Q LDS ++ R + K +R++ ++ + T D D A +++
Sbjct: 1124 QEDLDS-----ERAARNKAEKQKRDLGEELEALKTELED---------TLDSTATQQELR 1169
Query: 245 SVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLAR 304
+ + E E+T + +A ++ S E + +E + ++ ++ R
Sbjct: 1170 A--------KREQEVTVLKKALDEETRS----HEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 305 GKGNIETSSED-EDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAK 363
K N++ + + E + ADL E A +E++ + + + L D +R +A+
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 364 ---DLLALFNSFKPKGGVIFSVKIYPSEFGKE-RMKEEQVQGPVELL------------- 406
+ L N + G++ + + K+ Q+Q ELL
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 1337
Query: 407 --------SIPEDAPEKDWTSREKLRDY----------QFKRLKYYYAVVDCDSPETASK 448
+ +D +++ +++ L + K+L+ + + V+ E +
Sbjct: 1338 LRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEA-LEEGKKR 1396
Query: 449 IYEDCDGL--EFESSCSFID--------LRFIPDDITFD-DEPKDVASEVNLTAYKPKYF 497
++ + L ++E + D L+ DD+ D D + + S NL + K+
Sbjct: 1397 FQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS--NLEKKQRKFD 1454
Query: 498 TSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIE------ 551
A + DE D + +++E + L + E +EE+E
Sbjct: 1455 QLLAEEKNISSKYADERDR-----AEAEAREKETKALSLARALEEALEAKEELERTNKML 1509
Query: 552 ----EEL---QGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME 604
E+L + D G NV E +KS++ E Q+ + + L+ ++++ + ++ + +E
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHE---LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLE 1566
Query: 605 IKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASE------ 658
+ + ++ + ++K ++ L + + + +RKQ+ALA A +
Sbjct: 1567 VNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDL 1626
Query: 659 EELPSDVDLNDPYFAEEVKQIGINKKSVK----SAKDGTSPEEEI-------EIERQKAE 707
++L D E +KQ+ + +K +D + +EI E + + E
Sbjct: 1627 KDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLE 1686
Query: 708 MALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYT 767
L+ + ED + + +E + L+++ L + L ++ + A+ +
Sbjct: 1687 ADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELE 1746
Query: 768 SHLFNLDP-SDPNFKKTKAMEKILEEKARQR-------------ERKEQELTQAIKKKES 813
N++ SD K T+ E++ E A +R ER+ +EL + + E
Sbjct: 1747 EEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEG 1806
Query: 814 EIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
+ +S+ KS AL I ++ + EQ +AR+KQ
Sbjct: 1807 AV--KSKFKSTIAALEAKIAQLEEQVEQ-EAREKQ 1838
Score = 58.9 bits (141), Expect = 2e-08
Identities = 169/869 (19%), Positives = 335/869 (38%), Gaps = 146/869 (16%)
Query: 68 LKRFYDLSDSDSNLSGE-DSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSE 126
LK+ +L S+L + DS+ ++ K +K+K +E+++ L + ++T + E
Sbjct: 1110 LKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA--LKTELEDTLDSTATQQE 1167
Query: 127 NKTDLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTD-----SSL 181
+ + + + K K + S + +E QK+ + + + + ++L
Sbjct: 1168 LRAKREQEVTVLK-----KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANL 1222
Query: 182 EEKQRTLDSGTSEIVKSPRI------ECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCD 235
++ ++TL+ +++ R+ E ++++++ VQ + ++ SDG E+ D
Sbjct: 1223 DKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG--ERARAELND 1280
Query: 236 K-DALEEDSESVSEIGSDEESE-----NEITSVGRASGDDDGSEDDEEEDE--------- 280
K L+ + ESV+ + ++ E + ++ S+ D +E +
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 281 -DEEEDEDEDSEDDDK-----------------SDSGPDLARGKGNIETSSED----EDD 318
+EE + +D D++ SDS L +E E + +
Sbjct: 1341 LEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKE 1400
Query: 319 TADLFPEESGFEHAWRELDKDAPR---------ADEITRRLAVCNMDWDRLKAKDLLALF 369
+L + A+ +L+K R D +R V N++ + K LLA
Sbjct: 1401 IENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEE 1460
Query: 370 NSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQFK 429
+ K Y E ++R + E + + LS+ A E+ ++E+L K
Sbjct: 1461 KNISSK---------YADE--RDRAEAEAREKETKALSLAR-ALEEALEAKEELERTN-K 1507
Query: 430 RLKYYYAVVDCDSPETASKIYE---DCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASE 486
LK + + ++E LE + L + D++ ++ K + E
Sbjct: 1508 MLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK-LRLE 1566
Query: 487 VNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKK--EELLDMDFQAYLASSS 544
VN+ A K ++ DE + E+ L R+ + EL D Q LA+++
Sbjct: 1567 VNMQALKGQFERDLQAR--------DEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 545 EDEEE---IEEELQGDDGVNVEEDG---------KTKKSQKDDEEQIAKYRQLLQVIQEK 592
+ + E + ELQ D + E+ + K Q++ E+ A ++ +E
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Query: 593 EKKGK--ENDM----------EMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKK 640
EKK K E D+ E K KE E + + L G++ L EK++
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQD-----EKRR 1733
Query: 641 EKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIE 700
+ R+ + ++ L EE E SD AE++ ++S + +
Sbjct: 1734 LEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ---- 1789
Query: 701 IERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVN-D 759
+ERQ E+ +K+ E + K K K + E E V +
Sbjct: 1790 LERQNKELR----------------SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQE 1833
Query: 760 ARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKES 819
AR + T L D E+ + E+ +++ K + +K++ E E+ES
Sbjct: 1834 AREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEES 1893
Query: 820 QRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
QR I+ L + + TE +A ++
Sbjct: 1894 QR--INANRRKLQRELDEATESNEAMGRE 1920
Score = 42.7 bits (99), Expect = 0.001
Identities = 74/371 (19%), Positives = 149/371 (40%), Gaps = 64/371 (17%)
Query: 513 ETDHERIT----MLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKT 568
E H ++T +L + + E L + + + ++E+EE L + EE+ +
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Query: 569 KKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDK 628
++ Q + ++ + L + ++E+E ++ +E K +AE +K KLE
Sbjct: 939 QQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE---------KVTAEAKIK-KLE---- 984
Query: 629 LTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKS 688
++ L + +L +++K L E S DL EE K + K +K+
Sbjct: 985 ----DEILVMDDQNNKLSKERKLLEERIS--------DLTTNLAEEEEKAKNLTK--LKN 1030
Query: 689 AKDGTSPEEEIEIER-QKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKE 747
+ E E+ +++ +K+ L + + + +I + Q + K QL KK+E
Sbjct: 1031 KHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEE 1090
Query: 748 -------LIEDDFEVNVNDARFQAMYTSHLFNL--DPSDPNFKKTKA------------- 785
++D+ N + H+ +L D + KA
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEA 1150
Query: 786 ----MEKILEEKARQRE---RKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTK 838
+E L+ A Q+E ++EQE+T + KK + E S + ++++
Sbjct: 1151 LKTELEDTLDSTATQQELRAKREQEVT--VLKKALDEETRSHEAQVQEMRQKHAQAVEEL 1208
Query: 839 TEQFQARKKQK 849
TEQ + K+ K
Sbjct: 1209 TEQLEQFKRAK 1219
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 60.1 bits (144), Expect = 9e-09
Identities = 161/845 (19%), Positives = 313/845 (37%), Gaps = 125/845 (14%)
Query: 69 KRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENK 128
KR S S S+ + K+ I KKK QT+ E + + E +KE K + G+
Sbjct: 740 KRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDS-ELEKEIKSMSKIGAART 798
Query: 129 T--------DLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKN-------IV 173
T D D+S K K + N+ ++ + K+E++ +
Sbjct: 799 TKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVD 858
Query: 174 QHTTDSSLEE---KQRTLDSGTSEIVKSPRIECSKTRREMQSVVQL----------IMTR 220
+ TT L + K++ + T + K E S T E++ V + +
Sbjct: 859 KDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKK 918
Query: 221 DSDGYENSTDG--EMCDKDALEEDSESVSEIGSDEESENE------ITSVGRASGDDDGS 272
DG + + + D ED + S+ G++E+ + I + DG+
Sbjct: 919 VQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT 978
Query: 273 EDDEEEDE--------------------DEEEDEDEDSEDDDKSDSGPDLARGKGNIETS 312
E E +E ++ D+ S+ D+ + + GKG+ S
Sbjct: 979 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDS 1038
Query: 313 SEDEDDTADLFPEESGF-----EHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLA 367
SED+ + E + + + D + ++ + + CN RLK +L
Sbjct: 1039 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1098
Query: 368 LFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQ 427
N +R +E G S DA E +++K +
Sbjct: 1099 RRN------------------LSSKRNTKEIQSG-----SSSSDAEESSEDNKKKKQRTS 1135
Query: 428 FKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASEV 487
K+ +S T++K + S D I + + + + K V +
Sbjct: 1136 SKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENL 1195
Query: 488 NLTAYKPKYFTSAAMGTS-TVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSED 546
L+++ +S S +V +T D+ D + + K+ LL+ + +A L SS ED
Sbjct: 1196 VLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP--ENRIAKKMLLE-EIKANL-SSDED 1251
Query: 547 EEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIK 606
+E +G + GK + DEE K + E+D + E
Sbjct: 1252 GSSDDEPEEGK-----KRTGKQNEENPGDEEA-------------KNQVNSESDSDSEES 1293
Query: 607 WVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVD 666
P + ++++KL D + E+ + K+ K+ R ++ ++ E SE D D
Sbjct: 1294 KKPRYRH---RLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE-----DSD 1345
Query: 667 LNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYN 726
+ +EEV + ++ + EE +QK + + + ED S+ N
Sbjct: 1346 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSE 1405
Query: 727 KIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAM 786
+ +++K++ +++E E++ E +D++ + + D +T+
Sbjct: 1406 E-------EEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK--LRTETQ 1456
Query: 787 EKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARK 846
+ EE+ R++ E+E + ++ EIE S K +L + +TK Q +
Sbjct: 1457 NALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHR 1516
Query: 847 KQKVK 851
+K
Sbjct: 1517 NMVIK 1521
Score = 30.8 bits (68), Expect = 5.6
Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 43/241 (17%)
Query: 60 ISHSTTEDLKRFYDLSDSDSNLSGEDSKALSQ--KKIKKKKTQTKKEIDSK----NLVEK 113
++ S + LK+ D S+ S KA IKK +++++S+ + V K
Sbjct: 328 MNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNK 387
Query: 114 KKETKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKD-SKEFTQKNKKEKKNI 172
+K TK+ HK + K + +K + C + KKD SK + ++K+ +
Sbjct: 388 EKNTKE--HKVIDAKFETK----ARKGEKPCALE-------KKDISKSEAKLSRKQVDS- 433
Query: 173 VQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGE 232
+H + E+QRT S E KS R ++ YE + E
Sbjct: 434 -EHMHQNVPTEEQRTNKSTGGEHKKSDR-------------------KEEPQYEPANTSE 473
Query: 233 MCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSED 292
D D + S +I + E+ E+ S G DGS E+E E + S+D
Sbjct: 474 DLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQG--DGSSGTEQEVESSSVKLNISSKD 531
Query: 293 D 293
+
Sbjct: 532 N 532
Score = 30.0 bits (66), Expect = 9.5
Identities = 56/294 (19%), Positives = 119/294 (40%), Gaps = 48/294 (16%)
Query: 564 EDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKL 623
+ +T D +E +A +++ ++ N++ K + LK A + K K
Sbjct: 682 KQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKR 741
Query: 624 EGKDKLTPWE-----------QFLEKKKEK-------------KRLKRKQKALAEEASEE 659
+ K + + + KKK + K +K K A +++
Sbjct: 742 KRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKK 801
Query: 660 ELPSDVDLNDPYFAEEVKQIGINK--KSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDE 717
+P+ D + + K+ N+ K++K++++G+S + E + ER+ A +D+D
Sbjct: 802 RIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKD- 860
Query: 718 DSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSD 777
I+E + +L KK++ V+ + Q+ + + + +
Sbjct: 861 --------TTIME-------LRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETK 905
Query: 778 PNFK--KTKAMEKI---LEEKARQRERKEQ-ELTQAIKKKESEIEKESQRKSID 825
K KTK +K+ L + A + +K+Q + T KK+S+ E ++K D
Sbjct: 906 EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSD 959
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 60.1 bits (144), Expect = 9e-09
Identities = 161/845 (19%), Positives = 313/845 (37%), Gaps = 125/845 (14%)
Query: 69 KRFYDLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENK 128
KR S S S+ + K+ I KKK QT+ E + + E +KE K + G+
Sbjct: 778 KRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDS-ELEKEIKSMSKIGAART 836
Query: 129 T--------DLDNSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKN-------IV 173
T D D+S K K + N+ ++ + K+E++ +
Sbjct: 837 TKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVD 896
Query: 174 QHTTDSSLEE---KQRTLDSGTSEIVKSPRIECSKTRREMQSVVQL----------IMTR 220
+ TT L + K++ + T + K E S T E++ V + +
Sbjct: 897 KDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKK 956
Query: 221 DSDGYENSTDG--EMCDKDALEEDSESVSEIGSDEESENE------ITSVGRASGDDDGS 272
DG + + + D ED + S+ G++E+ + I + DG+
Sbjct: 957 VQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGT 1016
Query: 273 EDDEEEDE--------------------DEEEDEDEDSEDDDKSDSGPDLARGKGNIETS 312
E E +E ++ D+ S+ D+ + + GKG+ S
Sbjct: 1017 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDS 1076
Query: 313 SEDEDDTADLFPEESGF-----EHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLA 367
SED+ + E + + + D + ++ + + CN RLK +L
Sbjct: 1077 SEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRE 1136
Query: 368 LFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAPEKDWTSREKLRDYQ 427
N +R +E G S DA E +++K +
Sbjct: 1137 RRN------------------LSSKRNTKEIQSG-----SSSSDAEESSEDNKKKKQRTS 1173
Query: 428 FKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASEV 487
K+ +S T++K + S D I + + + + K V +
Sbjct: 1174 SKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENL 1233
Query: 488 NLTAYKPKYFTSAAMGTS-TVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSED 546
L+++ +S S +V +T D+ D + + K+ LL+ + +A L SS ED
Sbjct: 1234 VLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDP--ENRIAKKMLLE-EIKANL-SSDED 1289
Query: 547 EEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIK 606
+E +G + GK + DEE K + E+D + E
Sbjct: 1290 GSSDDEPEEGK-----KRTGKQNEENPGDEEA-------------KNQVNSESDSDSEES 1331
Query: 607 WVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVD 666
P + ++++KL D + E+ + K+ K+ R ++ ++ E SE D D
Sbjct: 1332 KKPRYRH---RLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSE-----DSD 1383
Query: 667 LNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYN 726
+ +EEV + ++ + EE +QK + + + ED S+ N
Sbjct: 1384 FQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSE 1443
Query: 727 KIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAM 786
+ +++K++ +++E E++ E +D++ + + D +T+
Sbjct: 1444 E-------EEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDK--LRTETQ 1494
Query: 787 EKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARK 846
+ EE+ R++ E+E + ++ EIE S K +L + +TK Q +
Sbjct: 1495 NALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTKLVLDEDEETKEPLVQVHR 1554
Query: 847 KQKVK 851
+K
Sbjct: 1555 NMVIK 1559
Score = 30.8 bits (68), Expect = 5.6
Identities = 57/241 (23%), Positives = 96/241 (39%), Gaps = 43/241 (17%)
Query: 60 ISHSTTEDLKRFYDLSDSDSNLSGEDSKALSQ--KKIKKKKTQTKKEIDSK----NLVEK 113
++ S + LK+ D S+ S KA IKK +++++S+ + V K
Sbjct: 366 MNSSYVKFLKQATDNSEISSATKLRQLKAFKSVLADIKKAHLALEEDLNSEFRAMDAVNK 425
Query: 114 KKETKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDSNISPKKD-SKEFTQKNKKEKKNI 172
+K TK+ HK + K + +K + C + KKD SK + ++K+ +
Sbjct: 426 EKNTKE--HKVIDAKFETK----ARKGEKPCALE-------KKDISKSEAKLSRKQVDS- 471
Query: 173 VQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGE 232
+H + E+QRT S E KS R ++ YE + E
Sbjct: 472 -EHMHQNVPTEEQRTNKSTGGEHKKSDR-------------------KEEPQYEPANTSE 511
Query: 233 MCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSED 292
D D + S +I + E+ E+ S G DGS E+E E + S+D
Sbjct: 512 DLDMDIVSVPSSVPEDIFENLETAMEVQSSVDHQG--DGSSGTEQEVESSSVKLNISSKD 569
Query: 293 D 293
+
Sbjct: 570 N 570
Score = 30.4 bits (67), Expect = 7.3
Identities = 29/131 (22%), Positives = 57/131 (43%), Gaps = 21/131 (16%)
Query: 209 EMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSD----EESENEITSVGR 264
++ ++VQ + + E S + + A+ ++++ +S GS+ E S+ E TS
Sbjct: 10 KLNTLVQKLHDFLAHSSEESEETSSPPRLAMNQNTDKISGSGSNSDMMENSKEEGTSSSE 69
Query: 265 ASGDDDGSE--------------DDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIE 310
S S DDE+ +DE +ED +E+ + + L +G ++
Sbjct: 70 KSKSSGSSRSKRKPSIVTKYVESDDEKPLDDETVNEDASNENSENDITMQSLPKGTVIVQ 129
Query: 311 TS---SEDEDD 318
+ED+DD
Sbjct: 130 PEPVLNEDKDD 140
Score = 30.0 bits (66), Expect = 9.5
Identities = 56/294 (19%), Positives = 119/294 (40%), Gaps = 48/294 (16%)
Query: 564 EDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKL 623
+ +T D +E +A +++ ++ N++ K + LK A + K K
Sbjct: 720 KQSETVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKR 779
Query: 624 EGKDKLTPWE-----------QFLEKKKEK-------------KRLKRKQKALAEEASEE 659
+ K + + + KKK + K +K K A +++
Sbjct: 780 KRKSSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKK 839
Query: 660 ELPSDVDLNDPYFAEEVKQIGINK--KSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDE 717
+P+ D + + K+ N+ K++K++++G+S + E + ER+ A +D+D
Sbjct: 840 RIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKD- 898
Query: 718 DSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSD 777
I+E + +L KK++ V+ + Q+ + + + +
Sbjct: 899 --------TTIME-------LRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETK 943
Query: 778 PNFK--KTKAMEKI---LEEKARQRERKEQ-ELTQAIKKKESEIEKESQRKSID 825
K KTK +K+ L + A + +K+Q + T KK+S+ E ++K D
Sbjct: 944 EKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSD 997
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 60.1 bits (144), Expect = 9e-09
Identities = 104/503 (20%), Positives = 214/503 (42%), Gaps = 57/503 (11%)
Query: 391 KERMKE-----EQVQGPVELLSIPEDAPEKDWTSREKLRDYQFKRLKYYYAVVD------ 439
KE+MKE +Q++ ++L +A +K EK F + +++D
Sbjct: 652 KEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKD 711
Query: 440 -----------CDSPETASKIYEDCDGLEFESSCSFIDLRFIPDDIT-FDDEPKDVASEV 487
D + +K E+ + L E +L+ +P ++ E +D + E+
Sbjct: 712 LLCNLELEGKITDLQKELNKEVEENEALR-EEVILLSELKSLPSEVERLRKEIQDKSEEL 770
Query: 488 NL-TAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSED 546
++ T+ K K F+ S V+ +E + + + + D +FQ + +
Sbjct: 771 HIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKST-DQEFQNFKTLHMDF 829
Query: 547 EEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKE-----NDM 601
E++ + L+ ++ +N E +K++QK D A +L QE ++K +E N+M
Sbjct: 830 EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEM 889
Query: 602 EMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKK----EKKRLKRKQKALAEEAS 657
E + + + + + + K +KL +Q LE+ K EK LK+ Q++L +
Sbjct: 890 EQLKEQLENRDSTLQTVEREKTLITEKL---QQTLEEVKTLTQEKDDLKQLQESL--QIE 944
Query: 658 EEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDE 717
++L SD+ + +Q+ + +++S K ++ + + L M+E+
Sbjct: 945 RDQLKSDIHDTVNMNIDTQEQL---RNALESLKQHQETINTLKSKISEEVSRNLHMEENT 1001
Query: 718 DSKKHFNYNKIV---EHQNLSKKKKKQL---MKKKELIEDD---FEVNVNDARFQAMYTS 768
K K+V + Q+L K + L +K E+IE F + Q M S
Sbjct: 1002 GETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLES 1061
Query: 769 HLFNLDPSDPNFKKTKAMEKILEEKAR---QRERKEQELTQAIKKKESEIEKESQRKSID 825
+ + + K+ M +E+ R +K+QE+ ++K I+KE +
Sbjct: 1062 VIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEI--VAQEKNHAIKKEGELSRTC 1119
Query: 826 PALSMLIKSIKTKTEQFQARKKQ 848
L+ + + +K K++Q Q +++Q
Sbjct: 1120 DRLAEVEEKLKEKSQQLQEKQQQ 1142
Score = 51.6 bits (122), Expect = 3e-06
Identities = 144/828 (17%), Positives = 316/828 (38%), Gaps = 96/828 (11%)
Query: 85 DSKALSQKKIKKKKTQTK-KEIDSKNLVEKKKETKKANHKGSENKTDLDNS-IGIKKMKT 142
D A ++K+K+K Q + K+ N+ E+ E +K ++ K +L N + ++ M+T
Sbjct: 1120 DRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMET 1179
Query: 143 SCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQ--HTTDSSLEEKQRTLDSG---TSEIVK 197
+ ++ ++ + + K +K K + + T L R +++ T E +K
Sbjct: 1180 E-RLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELK 1238
Query: 198 SPRIECSK--------TRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEI 249
I + R + Q+I T+D + E+ +E +V E+
Sbjct: 1239 IAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEV 1298
Query: 250 GSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDED-EDSEDDDKSDSGPDLARGKGN 308
+E+ NE+ + S D + E E +E ++S+++ KS L + + N
Sbjct: 1299 SETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKS-----LTKERDN 1353
Query: 309 IETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAKDLLAL 368
++T E + D EH L K + + L + D + K +++
Sbjct: 1354 LKTIKEALEVKHDQLK-----EHIRETLAKIQESQSKQEQSLNMKEKDNETTK---IVSE 1405
Query: 369 FNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPV-----ELLSIPEDAPEKDWTSREKL 423
FKPK + ++I K + V +L + E + +E +
Sbjct: 1406 MEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENI 1465
Query: 424 RDYQFKRL--KYYYAVVDC---DSPETASKIYEDCDGLEFESSCSFIDLRFIPDDI---- 474
++ K L + V C + ET +++ + E E S L I D +
Sbjct: 1466 KEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKI 1525
Query: 475 --TFDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEELL 532
++ E + +++ K + + + + + NR + +E +
Sbjct: 1526 QEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEI 1585
Query: 533 DMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQ-- 590
+ + E+ + ++E LQ + E + K+ +E+ ++ ++ V +
Sbjct: 1586 QI-----MIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQ 1640
Query: 591 -------------EKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLE 637
E +K EN I+ L E+ EEM ++ + +D L E+ L+
Sbjct: 1641 EKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEM-RSVTKERDDLRSVEETLK 1699
Query: 638 KKKEKKRLKRKQKALAEEASEEEL----------PSDVDLNDPYFAEEVKQIGINKKSVK 687
++++ + ++ + +EEL +D +E+ +I +K ++
Sbjct: 1700 VERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLE 1759
Query: 688 SAKDGTSPEE-EIEIERQKAEMALLMMDE---------DEDSKKHFNYNKIVEHQNLSKK 737
+ D ++ +I+ E + A M L E E + K N K +E+ N +
Sbjct: 1760 HSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQ 1819
Query: 738 KKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQR 797
+K Q +K E + +VN+ + + L K+ K L + +
Sbjct: 1820 EKIQELKANEHQLITLKKDVNETQKKVSEMEQL---------KKQIKDQSLTLSKLEIEN 1870
Query: 798 ERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQAR 845
Q+L + +++ +S +++ + ++ L + +K ++ +AR
Sbjct: 1871 LNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKAR 1918
Score = 41.6 bits (96), Expect = 0.003
Identities = 77/377 (20%), Positives = 156/377 (41%), Gaps = 57/377 (15%)
Query: 515 DHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQG--DDGVNVEEDGKTKKSQ 572
+ E + +L + KK+ Q +A + E EL D VEE K K Q
Sbjct: 1083 NQEELRLLGDELKKQ-------QEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQ 1135
Query: 573 KDDEEQIAKYRQLLQVIQE-KEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTP 631
+++Q QLL V +E E + K N++E + + + E M +LE KL
Sbjct: 1136 LQEKQQ-----QLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNE 1190
Query: 632 -WEQFLEKKKEKKRLKRKQKALAEE------------ASEEELPSDVDLNDPYFAEEVKQ 678
+E+ KE+K LK QK+ E A+ + ++ + + E +
Sbjct: 1191 NYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQET 1250
Query: 679 IGINKKSVKSA-----------KDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNK 727
I ++SV K T +EEI + ++ E+ L + E ++++ N +
Sbjct: 1251 IDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQEL-LPNVKEVSETQETMNELE 1309
Query: 728 IVEHQNLSKKKKK--QLMKKKELIEDDFEVNVNDARFQAMYTSHLFNL--------DPSD 777
++ Q+ +K ++ ++ + + F+ + + + +L + D
Sbjct: 1310 LLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLK 1369
Query: 778 PNFKKTKAMEKILEEKARQRE-----RKEQELTQAIKKKESEIEKESQRKSIDPALSMLI 832
+ ++T A KI E +++Q + K+ E T+ + + E K+S I+ + L
Sbjct: 1370 EHIRETLA--KIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLS 1427
Query: 833 KSIKTKTEQFQARKKQK 849
K ++ ++ ++ K+K
Sbjct: 1428 KRLQESHDEMKSVAKEK 1444
Score = 40.8 bits (94), Expect = 0.005
Identities = 73/319 (22%), Positives = 133/319 (41%), Gaps = 44/319 (13%)
Query: 546 DEEEIEEELQG--DDGVNVEEDGKTKKSQKDDEEQIAKYRQLL---QVIQEKEKKGKEND 600
++E IE EL D N+ D + +++K++ E K + L + ++ K KK +E
Sbjct: 492 NQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQ 551
Query: 601 MEMEIKWVPGLKESAE---EMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEAS 657
+ EI + L + AE + ++N+L K +L EK+ + K+L+ + E
Sbjct: 552 LIHEISNLKNLVKHAEVYNQDLENELSSKVEL-----LREKEDQIKKLQEYIDSQKLENI 606
Query: 658 EEELPSDVD-LNDPYFAEEVKQIGINKKSVKSAKDGTSP---EEEIEIERQKAEMALLMM 713
+ +L ++ + DP +++KQ + ++V S E +E++ + E+A
Sbjct: 607 KMDLSYSLESIEDP---KQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYK 663
Query: 714 DEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLF-N 772
+ D + + L KKK Q+ +KEL E+ + L N
Sbjct: 664 QMENDIQLY--------QSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCN 715
Query: 773 LDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLI 832
L+ K + K +EE RE E L +K SE+E+ L
Sbjct: 716 LELEGKITDLQKELNKEVEENEALRE--EVILLSELKSLPSEVER-------------LR 760
Query: 833 KSIKTKTEQFQARKKQKVK 851
K I+ K+E+ +K K
Sbjct: 761 KEIQDKSEELHIITSEKDK 779
Score = 40.8 bits (94), Expect = 0.005
Identities = 58/259 (22%), Positives = 116/259 (44%), Gaps = 23/259 (8%)
Query: 498 TSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEE-----IEE 552
TS A G V T + + +T + E++ +++ + A S +E +++
Sbjct: 2351 TSLASGAQ-VNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIKMQK 2409
Query: 553 ELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKG----KENDMEMEIKWV 608
EL+ + + + K +S K E K ++ +QV+Q+K G KE ++++K V
Sbjct: 2410 ELEVTNDIIAKLQAKVHESNKCLE----KTKETIQVLQDKVALGAKPYKEEIEDLKMKLV 2465
Query: 609 PGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSD---- 664
K E+M KN E + +++ + +E +KE RL R+ +++A + + S+
Sbjct: 2466 ---KIDLEKM-KNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTDP 2521
Query: 665 VDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHF- 723
N P I N K++ + E+EI +Q+ E + +E + +H
Sbjct: 2522 QPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLS 2581
Query: 724 NYNKIVEHQNLSKKKKKQL 742
N K + + L ++ KQ+
Sbjct: 2582 NEVKTWKERTLKREAHKQV 2600
Score = 37.7 bits (86), Expect = 0.045
Identities = 139/776 (17%), Positives = 308/776 (39%), Gaps = 90/776 (11%)
Query: 93 KIKKKKTQTKKEIDSKNLVEKKKE--TKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDS 150
++++ K Q + + VE++K T+K E KT +K+++ S + + D
Sbjct: 888 EMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 947
Query: 151 NISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTS----EIVKSPRIE--CS 204
S D+ +++ +N ++ SL++ Q T+++ S E+ ++ +E
Sbjct: 948 LKSDIHDTVNMNIDTQEQLRNALE-----SLKQHQETINTLKSKISEEVSRNLHMEENTG 1002
Query: 205 KTRREMQS-VVQLIMTRDSDGYENST-DGEMCDKDALEEDSESVSEIGSDEESENEITSV 262
+T+ E Q +V + +D + T ++ D + +E+ + S I E + + SV
Sbjct: 1003 ETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESV 1062
Query: 263 GRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDE-DDTAD 321
+ + D +E E E+++E D+ ++ + N E E T D
Sbjct: 1063 --IAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCD 1120
Query: 322 LFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLKAK--DLLALFNSFKPKGGVI 379
E +L + + + E ++L + ++ K ++ L N K K +
Sbjct: 1121 RLAEVE------EKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTL 1174
Query: 380 FSVKIYPSEFGKERMKE-EQVQGPVELLSIPEDAPEKDWTSREKLRDYQFKRLKYYYAVV 438
++ E ++ + E+V+ + + ++ + T R+ LR Y
Sbjct: 1175 EHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGY------------ 1222
Query: 439 DCDSPETASKIYE-DCDGLEFESSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYKPKYF 497
I E + GL+ + + T D+ + V+ +
Sbjct: 1223 ----------IREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEK----------- 1261
Query: 498 TSAAMGTSTVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEE-ELQG 556
T+ + T +E + + E I +L+ +++ELL + SE +E + E EL
Sbjct: 1262 TAQIINTQDLEKSHTKLQEE-IPVLH---EEQELLPN-----VKEVSETQETMNELEL-- 1310
Query: 557 DDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEME-IKWVPGLKESA 615
+ E TK S ++ + R L + QE +++ K E + +K + E
Sbjct: 1311 -----LTEQSTTKDSTTLARIEMERLR-LNEKFQESQEEIKSLTKERDNLKTIKEALEVK 1364
Query: 616 EEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEEL--PSDVDLNDPYFA 673
+ +K + ++ L ++ K+++ +K K + SE E P D L
Sbjct: 1365 HDQLKEHI--RETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSAL----LR 1418
Query: 674 EEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQN 733
E++ +G++K+ +S + S +E + ++ E+ D+ +++ K + +
Sbjct: 1419 IEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEE 1478
Query: 734 LSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEK 793
L K +K++E ++ VN+++ + K + EK +
Sbjct: 1479 L--KVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFN 1536
Query: 794 ARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQK 849
+Q ++++ + + KE K+S +SI+ + L ++ E+ Q K+K
Sbjct: 1537 IKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEK 1592
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 59.3 bits (142), Expect = 1e-08
Identities = 166/870 (19%), Positives = 328/870 (37%), Gaps = 134/870 (15%)
Query: 74 LSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKK--KETKKANHKGSENKTDL 131
+++ S L+ E+ KA + KI+ K+ +++ + E+K +E +KA K TDL
Sbjct: 1008 IAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDL 1067
Query: 132 DNSIG-----IKKMKTS-CKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQ 185
+ I I ++K K + + + + E KN K V + + E Q
Sbjct: 1068 QDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALK---VVRELQAQIAELQ 1124
Query: 186 RTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSES 245
+S K+ R + K +R++ ++ + T E++ D ++ + +
Sbjct: 1125 EDFES-----EKASRNKAEKQKRDLSEELEALKTE----LEDTLDTTAAQQELRTKREQE 1175
Query: 246 VSEI--GSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLA 303
V+E+ +EE++N + +D + E+ E E
Sbjct: 1176 VAELKKALEEETKNHEAQI----------QDMRQRHATALEELSEQLE---------QAK 1216
Query: 304 RGKGNIETSSED-EDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCNMDWDRLK- 361
R K N+E + + E D +L E + E + + D + L + DRL+
Sbjct: 1217 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
Query: 362 --AKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMK-EEQVQGPVELLS----------- 407
A+ L N ++ + +F K+ E Q+Q ELL
Sbjct: 1277 ELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSS 1336
Query: 408 -IPEDAPEKDWTSREKLRDYQF-KRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFI 465
I + EK+ ++ + + K L+ + +T K+ +D +E
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIE-------- 1388
Query: 466 DLRFIPDDITFDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHER--ITMLN 523
L + D E E AY T + ++T D DH+R + L
Sbjct: 1389 SLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVD-LDHQRQVASNLE 1447
Query: 524 RKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYR 583
+K KK + L + ++ A +E+ + E E + + + +++ + EE + +
Sbjct: 1448 KKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNK 1507
Query: 584 QLL----QVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWE------ 633
QL ++ K+ GK N E+E K L++ EEM E +D+L E
Sbjct: 1508 QLRADMEDLMSSKDDVGK-NVHELE-KSKRALEQQVEEMRTQLEELEDELQATEDAKLRL 1565
Query: 634 ---------QFL-------EKKKEKKRL--------------KRKQKALA------EEAS 657
QF E+ +EKKRL +RKQ+ALA E
Sbjct: 1566 EVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEID 1625
Query: 658 EEELPSDVDLNDPYFAEEVKQIGINKKSVK-----------SAKDGTSPEEEIEIERQKA 706
++L + ++ + E +KQ+ + +K S + + +E E + +
Sbjct: 1626 LKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSL 1685
Query: 707 EMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMY 766
E +L + E+ S + + E L+ + K L+++ + A+ +
Sbjct: 1686 EAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEEL 1745
Query: 767 TSHLFNLDPSDPNFKKTKAMEKILEEK---ARQRERKEQELTQAIKKKESEIEKESQ--R 821
N++ + F+KT L + R +K Q ++++ E++ + Q
Sbjct: 1746 EEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELE 1805
Query: 822 KSIDPALSMLIKSIKTKTEQFQARKKQKVK 851
++ I +++ K Q + + +Q+ K
Sbjct: 1806 GAVKSKFKATISALEAKIGQLEEQLEQEAK 1835
Score = 49.7 bits (117), Expect = 1e-05
Identities = 68/346 (19%), Positives = 141/346 (40%), Gaps = 28/346 (8%)
Query: 512 DETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKS 571
+E H+ + + + ++ ++L + + A + EE+++EE + +E+ K
Sbjct: 921 EEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKI 980
Query: 572 QKDDEEQIAKYRQLLQVIQEK--------EKKGKENDMEMEIKWVPGLKESAEEMVKNKL 623
+K +EE + Q + I+EK E + + E + K + ++ E M+ +
Sbjct: 981 KKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLE 1040
Query: 624 EGKDKLTPWEQFLEKKKEK---------KRLKRKQKALAE-----EASEEELPSDVDLND 669
E K Q LEK K K ++ Q + E EEEL + D
Sbjct: 1041 ERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGD 1100
Query: 670 PYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKK---HFNYN 726
+ + + ++ + E + R KAE + E+ ++ K +
Sbjct: 1101 DETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLD 1160
Query: 727 KIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAM 786
Q L K+++++ + K+ +E+ E ++A+ Q M H L+ ++ K
Sbjct: 1161 TTAAQQELRTKREQEVAELKKALEE--ETKNHEAQIQDMRQRHATALEELSEQLEQAKRF 1218
Query: 787 EKILEEKARQRERKEQELTQAIK-KKESEIEKESQRKSIDPALSML 831
+ LE+ + E +EL +K ++ + E E +RK +D + L
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQEL 1264
Score = 49.3 bits (116), Expect = 2e-05
Identities = 67/276 (24%), Positives = 123/276 (44%), Gaps = 36/276 (13%)
Query: 573 KDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPW 632
+ +EE AK +LL+V +EK+ K + EME K L+E + ++ +L+ + +L
Sbjct: 849 RQEEELQAKDEELLKV-KEKQTKVEGELEEMERKHQQLLEE--KNILAEQLQAETEL--- 902
Query: 633 EQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDG 692
F E ++ + RL K++ L E + E + + EE QI N+K A
Sbjct: 903 --FAEAEEMRARLAAKKQELEEILHDLESRVEEE-------EERNQILQNEKKKMQAHIQ 953
Query: 693 TSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDD 752
E+ E E + ++ L + + KK ++E QN + +K+K+L+ED
Sbjct: 954 DLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQN------SKFIKEKKLMEDR 1007
Query: 753 FEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKI----LEEKARQRERKEQELTQAI 808
A +S L + N K + +++ LEE+ ++ E+ QEL +A
Sbjct: 1008 I----------AECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAK 1057
Query: 809 KKKESE-IEKESQRKSIDPALSMLIKSIKTKTEQFQ 843
+K + E + + Q + + L + K E+ Q
Sbjct: 1058 RKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQ 1093
Score = 44.3 bits (103), Expect = 5e-04
Identities = 71/345 (20%), Positives = 152/345 (44%), Gaps = 24/345 (6%)
Query: 517 ERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDE 576
E +L + + E L + + A + ++E+EE L + EE+ + + Q + +
Sbjct: 887 EEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKK 946
Query: 577 EQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMV----KNKLEGKDKLTPW 632
+ A + L + + E+E ++ +E ++ +K+ EE++ +N K+K
Sbjct: 947 KMQAHIQDLEEQLDEEEGARQKLQLE-KVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 633 EQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDG 692
++ E + + K K LA+ +++E+ DL + EE + + K K +
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMIS-DLEERLKKEEKTRQELEKAKRKLDGET 1064
Query: 693 TSPEEEI-EIERQKAEMALLMMDEDEDSKKHF-NYNKIVEHQNLSKKKKKQLMKKKELIE 750
T +++I E++ Q E+ L + ++E+ + + H+N + K ++L + ++
Sbjct: 1065 TDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQ 1124
Query: 751 DDFE---VNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRE---RKEQEL 804
+DFE + N A Q D S+ +E L+ A Q+E ++EQE+
Sbjct: 1125 EDFESEKASRNKAEKQ--------KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV 1176
Query: 805 TQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKTEQFQARKKQK 849
+ KK E E ++ I +++ +EQ + K+ K
Sbjct: 1177 AEL--KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFK 1219
Score = 30.8 bits (68), Expect = 5.6
Identities = 21/103 (20%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 725 YNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTK 784
+ K+ +++++++ K +EL++ + + + M H L+ + ++ +
Sbjct: 838 FTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQ 897
Query: 785 AMEKILEEKARQRER---KEQELTQAIKKKESEIEKESQRKSI 824
A ++ E R R K+QEL + + ES +E+E +R I
Sbjct: 898 AETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQI 940
>gi|51477718 TATA box binding protein-associated factor, RNA
polymerase II, Q [Homo sapiens]
Length = 462
Score = 59.3 bits (142), Expect = 1e-08
Identities = 43/148 (29%), Positives = 76/148 (51%), Gaps = 12/148 (8%)
Query: 164 KNKKEKKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSD 223
KN ++K+ T + + + S +E ++SP +E ++ +R ++S + + TR
Sbjct: 227 KNVRKKRF---RKTQKKVPDVKEMEKSSFTEYIESPDVE-NEVKRLLRSDAEAVSTRWEV 282
Query: 224 GYENSTDGEMCDKDALEE-------DSESVSEIGSDEESENEITSVGRASGDDDGSEDDE 276
E+ T E+ + ++ S S+ + E+ S R++ DDD EDDE
Sbjct: 283 IAEDGTK-EIESQGSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDE 341
Query: 277 EEDEDEEEDEDEDSEDDDKSDSGPDLAR 304
+EDEDE+EDEDED E++++ S L R
Sbjct: 342 DEDEDEDEDEDEDKEEEEEDCSEEYLER 369
Score = 36.6 bits (83), Expect = 0.10
Identities = 37/150 (24%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 155 KKDSKEFTQKNKKEKKNIVQHTTDSSLE-EKQRTLDSGTSEIVKSPRIECSKTRREMQSV 213
+K K+ + EK + ++ +E E +R L S + + +E++S
Sbjct: 235 RKTQKKVPDVKEMEKSSFTEYIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQ 294
Query: 214 VQLIMTRDSDGYENSTDGEMCDK-DALEE---DSESVSEIGSDEESENEITSVGRASGDD 269
+ S G + G + D L E DS S ++ DE+ E+E D+
Sbjct: 295 GSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDE-----DEDEDE 349
Query: 270 DGSEDDEEEDEDEEEDEDEDSEDDDKSDSG 299
D ED EEE+ED E+ E + +SG
Sbjct: 350 DEDEDKEEEEEDCSEEYLERQLQAEFIESG 379
Score = 33.5 bits (75), Expect = 0.86
Identities = 52/253 (20%), Positives = 99/253 (39%), Gaps = 32/253 (12%)
Query: 618 MVKNKLEGKDKLTPWEQFLE---KKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAE 674
+V+ K G+++ W+ + K KKR ++ QK + + E+ + P
Sbjct: 204 IVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYIESPDVEN 263
Query: 675 EVKQI------GINKKSVKSAKDGTSPEEEIEIERQKAEMALLM---MDEDEDSKKHFNY 725
EVK++ ++ + A+DGT EIE Q + L+ M + Y
Sbjct: 264 EVKRLLRSDAEAVSTRWEVIAEDGTK-----EIESQGSIPGFLISSGMSSHKQGHTSSEY 318
Query: 726 NKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKA 785
+ + E + S+ + + ED+ E D + D S+ ++
Sbjct: 319 DMLREMFSDSRSNNDDDEDEDDEDEDEDEDEDEDEDKEEE------EEDCSEEYLERQLQ 372
Query: 786 MEKILEEKARQRERKE---QELTQAIKKKESEIEKESQRKSIDPALSMLIKSIKTKT--- 839
E I + R E E+ + I+KKE ++ K + L M ++++ K
Sbjct: 373 AEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKAQRQKDLIMKVENLTLKNHFQ 432
Query: 840 ---EQFQARKKQK 849
EQ + ++KQK
Sbjct: 433 SVLEQLELQEKQK 445
Score = 31.6 bits (70), Expect = 3.3
Identities = 37/148 (25%), Positives = 63/148 (42%), Gaps = 22/148 (14%)
Query: 205 KTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVS-------EIGSDE-ESE 256
KT++++ V ++ + ++ Y S D E K L D+E+VS E G+ E ES+
Sbjct: 236 KTQKKVPDVKEMEKSSFTE-YIESPDVENEVKRLLRSDAEAVSTRWEVIAEDGTKEIESQ 294
Query: 257 NEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDS-----EDDDKSDSGPDLARGKGNIET 311
I +SG + + D + DS +D+D+ D D E
Sbjct: 295 GSIPGFLISSGMSSHKQGHTSSEYDMLREMFSDSRSNNDDDEDEDDEDED--------ED 346
Query: 312 SSEDEDDTADLFPEESGFEHAWRELDKD 339
EDED+ + E+ E+ R+L +
Sbjct: 347 EDEDEDEDKEEEEEDCSEEYLERQLQAE 374
Score = 30.4 bits (67), Expect = 7.3
Identities = 93/453 (20%), Positives = 169/453 (37%), Gaps = 75/453 (16%)
Query: 245 SVSEIGSDEESENEI---TSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPD 301
S SE+ S +E + + + S D ++ + DE+ D DS + + +
Sbjct: 21 STSEVTSQQEPQIPVDRGSETTYESSADIAGDEGTQIPADEDTQTDADSSAQAAAQAPEN 80
Query: 302 LARGKGNIETSSEDEDDTADLFPEESGFEHAWRELD---------KDAPRADEITR-RLA 351
GK E+ E D+ + F EHA + KD + D + R A
Sbjct: 81 FQEGKDMSESQDEVPDEVENQFILRLPLEHACTVRNLARSQSVKMKDKLKIDLLPDGRHA 140
Query: 352 VCNMDWDRLKAK--DLLALFNSFKPKGGVIF------SVKIYPSEFGKERMKEEQVQGPV 403
V ++ L AK DL + S + F S + + G + E+
Sbjct: 141 VVEVEDVPLAAKLVDLPCVIESLRTLDKKTFYKTADISQMLVCTADGDIHLSPEEPAAST 200
Query: 404 ELLSIPEDAPEKDWTSREK----------LRDYQFKRL-KYYYAVVDCDSPETASKI-YE 451
+ P +K+ EK L++ + KR K V D E +S Y
Sbjct: 201 D----PNIVRKKERGREEKCVWKHGITPPLKNVRKKRFRKTQKKVPDVKEMEKSSFTEYI 256
Query: 452 DCDGLEFE------SSCSFIDLRFIPDDITFDDEPKDVASEVNLTAYKPKYFTSAAMGTS 505
+ +E E S + R+ ++ +D K++ S+ ++ P + S+ M +
Sbjct: 257 ESPDVENEVKRLLRSDAEAVSTRW---EVIAEDGTKEIESQGSI----PGFLISSGMSSH 309
Query: 506 TVEITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEED 565
T E D R + + ++ D D EDE+E E+E +ED
Sbjct: 310 KQGHTSSEYDMLREMFSDSRSNNDDDEDED--------DEDEDEDEDE---------DED 352
Query: 566 GKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKE--NDMEMEIKWVPGLKESAEEMVKNKL 623
++ ++D E+ + + + I+ + + E + + MEI+ KE ++NK
Sbjct: 353 EDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGTSSIVMEIQKQIEKKEKKLHKIQNKA 412
Query: 624 EGKDKLTPWEQFLEKKK------EKKRLKRKQK 650
+ + L + L K E+ L+ KQK
Sbjct: 413 QRQKDLIMKVENLTLKNHFQSVLEQLELQEKQK 445
>gi|34577114 cytomatrix protein p110 [Homo sapiens]
Length = 957
Score = 58.9 bits (141), Expect = 2e-08
Identities = 75/322 (23%), Positives = 134/322 (41%), Gaps = 45/322 (13%)
Query: 548 EEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKW 607
E ++E+ + DD +EE +K KD +E++ L + EKE
Sbjct: 598 ERLKEQRERDDRERLEEIESFRKENKDLKEKV---NALQAELTEKESS------------ 642
Query: 608 VPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDL 667
+ LKE A + L+ KL E +E+KKE+ K A+ + D +
Sbjct: 643 LIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEEC-----SKLEAQLKKAHNIEDDSRM 697
Query: 668 NDPYFAEEVKQIGINKKSVKSAKDGTSPEEEI--------EIERQK-------AEMALLM 712
N P FA+++KQ+ +K++ + + E+ E+E +K AE+ L
Sbjct: 698 N-PEFADQIKQL--DKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESLT 754
Query: 713 MDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQAMYTSHLFN 772
+ +D K + +Q L KKK QL+++ ED N + + + +
Sbjct: 755 LRHMKDQNK--KVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKT 812
Query: 773 LDPSDPNFKKTKAMEKILEEK----ARQRERKEQELTQAIKKKESEIEKESQRKSIDPAL 828
D + + ++ L EK A R + ++L + ++ K+ + K + AL
Sbjct: 813 RQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMKQEALLAAISEKDANIAL 872
Query: 829 SMLIKSIKTKT-EQFQARKKQK 849
L S K KT E+ A K++K
Sbjct: 873 LELSASKKKKTQEEVMALKREK 894
Score = 45.4 bits (106), Expect = 2e-04
Identities = 59/300 (19%), Positives = 121/300 (40%), Gaps = 49/300 (16%)
Query: 548 EEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKW 607
E ++E+L+ D + K Q D L + + EKE+
Sbjct: 549 ENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERI------------ 596
Query: 608 VPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDL 667
+ LKE E + +++L E F +KE K LK K AL E +E+E S +DL
Sbjct: 597 IERLKEQRER------DDRERLEEIESF---RKENKDLKEKVNALQAELTEKE-SSLIDL 646
Query: 668 NDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDE--------DS 719
+ A + G+ + S + + +++ E + +A++ ED+ D
Sbjct: 647 KE--HASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQ 704
Query: 720 KKHFNYNKIVEHQNLSKKKKK-----QLMKKKELIEDDFEVNVNDARFQAMYTSHLFNLD 774
K + K + + +++K+ E ++D + + A +++ H+ + +
Sbjct: 705 IKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKI--AELESLTLRHMKDQN 762
Query: 775 PSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQRKSIDPALSMLIKS 834
N K + +EK +K +L + ++++E + SQ I+ ++ L K+
Sbjct: 763 KKVANLKHNQQLEK----------KKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKT 812
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 58.9 bits (141), Expect = 2e-08
Identities = 79/347 (22%), Positives = 147/347 (42%), Gaps = 34/347 (9%)
Query: 522 LNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDG-KTKKSQKDDEEQIA 580
+ +K K E Q ++ + EE+ ++E++G V++ K K+ QK +
Sbjct: 190 IEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKE 249
Query: 581 KYRQLLQVIQEKEKKGKENDMEMEIK-WVPG-LKESAEEMVKNKL--EGKDKLTPWEQFL 636
K + + + E+K + I +V G LK + L E + TP L
Sbjct: 250 KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPAL 309
Query: 637 EKKKEKKR---------LKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVK 687
E+K+ +K+ K+K+K ++ SE+E DV+ +P A E KQ G K + +
Sbjct: 310 EEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQ-GTVKIAAQ 368
Query: 688 SAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKE 747
+A +E+ + ++ AE+ + E +KH K + ++ K+ K +
Sbjct: 369 AAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTER 428
Query: 748 LIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQA 807
E+ V++ A P K TK +E+ + ++ + + +
Sbjct: 429 AKEEIGAVSIKKA-------------VPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEP 475
Query: 808 IKKKESEI-----EKESQRKSIDPALSMLIKSIKTKTEQFQARKKQK 849
IK KE ++ EKE + K D +S K +K K Q Q +K++K
Sbjct: 476 IKGKEEKVPASLKEKEPETKK-DEKMSKAGKEVKPKPPQLQGKKEEK 521
Score = 54.7 bits (130), Expect = 4e-07
Identities = 87/363 (23%), Positives = 145/363 (39%), Gaps = 66/363 (18%)
Query: 543 SSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQ--VIQEKEKKGKEND 600
SSEDEE+ + + D G E + K+ KD E+ K + +Q V ++++KGKE
Sbjct: 115 SSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKV 174
Query: 601 MEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQ----------K 650
E E P K + +E ++ K + + K EQ K EK K K+ K
Sbjct: 175 REKE---KPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVK 231
Query: 651 ALAEEASE-EELPSDVDLNDPYFAEEVKQIGINKKSVKSA----------------KDGT 693
A + E ++ PS P E+ ++ ++K K K G
Sbjct: 232 QTAAKVKEVQKTPSK-----PKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQ 286
Query: 694 SPEEEIEIERQKAEM---ALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIE 750
SP + ++A A ++E E KK E +KKK+K+ +KKK E
Sbjct: 287 SPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSE----TKKKEKEDIKKKSEKE 342
Query: 751 DDFEVNVNDARFQAMYTSHLFNL--------DPSDPNFKKTKAMEKILEEKARQRERKEQ 802
+V + + + D + KKTK ++ + K +++E+KE+
Sbjct: 343 TAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEK 402
Query: 803 ELTQAIK-KKESEIEKESQRK-------------SIDPALSMLIKSIKTKTEQFQARKKQ 848
+ A KKE + + Q K SI A+ + TKT + + RK++
Sbjct: 403 HVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEK 462
Query: 849 KVK 851
K
Sbjct: 463 SGK 465
Score = 47.4 bits (111), Expect = 6e-05
Identities = 116/630 (18%), Positives = 241/630 (38%), Gaps = 76/630 (12%)
Query: 243 SESVSEIGSD---------EESENEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDD 293
+ S+++IGSD EE+ + I D SED+E++D DE+ D+ E E
Sbjct: 78 ASSIAKIGSDPLKLVRDAMEETTDWIYGFFSLLSDIISSEDEEDDDGDEDTDKGEIDE-- 135
Query: 294 DKSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVC 353
P L + + + + + + E + ++ H +E K+ R E + A
Sbjct: 136 ------PPLRKKEIHKDKTEKQEKPERKI---QTKVTHKEKEKGKEKVREKEKPEKKATH 186
Query: 354 NMDWDRLKAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAP 413
++ + + L K K +E +E+ K+E G E +
Sbjct: 187 KEKIEKKEKPETKTLAKEQK---------KAKTAEKSEEKTKKEVKGGKQEKVKQTAAKV 237
Query: 414 EKDWTSREKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDD 473
++ + K ++ + D + A +E D F C ++ F+ D
Sbjct: 238 KEVQKTPSKPKEKE-------------DKEKAAVSKHEQKDQYAF---CRYMIDIFVHGD 281
Query: 474 ITFDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHER------ITMLNRKFK 527
+ P A P T A + +E + E+ +T +K +
Sbjct: 282 LKPGQSP----------AIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKE 331
Query: 528 KEELLDM-DFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLL 586
KE++ + + + ++ + E QG V + KK +K ++ + K ++
Sbjct: 332 KEDIKKKSEKETAIDVEKKEPGKASETKQGT--VKIAAQAAAKKDEKKEDSK--KTKKPA 387
Query: 587 QVIQEKEKKGKENDMEMEIKWVPGLKES--AEEMVKNKLE-GKDKL--TPWEQFLEKKKE 641
+V Q K KK ++ + +E P + S +++ VK K E K+++ ++ + KKE
Sbjct: 388 EVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKE 447
Query: 642 KKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEI 701
+K K ++ + +E S + D EE + +K ++ KD + E+
Sbjct: 448 EKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEV 507
Query: 702 ERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDAR 761
+ + ++ ++ E K I E + K+ ++K ++ + +
Sbjct: 508 KPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQ---DIVKPEKTVSHGKPEEKVLKQ 564
Query: 762 FQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESEIEKESQR 821
+A+ P+ + + I +K + + E+T++ KKK EKES+
Sbjct: 565 VKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKE 624
Query: 822 KSIDPALSMLIKSIKTKTEQFQARKKQKVK 851
K+ + + + T+ E Q K +
Sbjct: 625 KA--DMKHLREEKVSTRKESLQLHNVTKAE 652
Score = 41.2 bits (95), Expect = 0.004
Identities = 54/240 (22%), Positives = 100/240 (41%), Gaps = 29/240 (12%)
Query: 86 SKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLD---NSIGIKKMKT 142
S AL +K+ +KKK + K++ S E KK+ K+ K SE +T +D G
Sbjct: 306 SPALEEKEGEKKKAE--KKVTS----ETKKKEKEDIKKKSEKETAIDVEKKEPGKASETK 359
Query: 143 SCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGTS----EIVKS 198
KI + + KKD K+ K K +K V+ E+K++ ++ S V S
Sbjct: 360 QGTVKIAAQAAAKKDEKKEDSK-KTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPS 418
Query: 199 PRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESENE 258
+ +KT R + + + + + G + + +++ +E S S I D+E
Sbjct: 419 DKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIK- 477
Query: 259 ITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDD 318
G E E+ +E E E +D+ S +G ++ ++ E++ +
Sbjct: 478 ------------GKE--EKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPE 523
Score = 39.7 bits (91), Expect = 0.012
Identities = 47/236 (19%), Positives = 92/236 (38%), Gaps = 14/236 (5%)
Query: 91 QKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNSIGIKKMKTSCKFKIDS 150
++KI+ K T +KE + + EK+K KKA HK K + + + K + K S
Sbjct: 155 ERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKS 214
Query: 151 NISPKKDSKEFTQKNKKE---KKNIVQHTTDSSLEEKQRTLDSGTSEIVKSPRIECSKTR 207
KK+ K Q+ K+ K VQ T E++ + + + K C
Sbjct: 215 EEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFC---- 270
Query: 208 REMQSVVQLIMTRD-SDGYENSTDGEMCDKDALEEDSESVS---EIGSDEESENEITSVG 263
+ ++ + + D G + + + A S + + G +++E ++TS
Sbjct: 271 ---RYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSET 327
Query: 264 RASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIETSSEDEDDT 319
+ +D + E+E + E ++ + K + A+ + ED T
Sbjct: 328 KKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKT 383
Score = 35.4 bits (80), Expect = 0.23
Identities = 33/136 (24%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
Query: 73 DLSDSDSNLSGEDSKALSQKKIKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLD 132
D D D++ D L +K+I K KT+ +++ E+K +T K HK E +
Sbjct: 122 DDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEK------PERKIQT-KVTHKEKEKGKEKV 174
Query: 133 NSIGIKKMKTSCKFKIDSNISPKKDSKEFTQKNKKEKKNIVQHTTDSSLEEKQRTLDSGT 192
+ K + K KI+ P ++K ++ KK K T + S E+ ++ + G
Sbjct: 175 REKEKPEKKATHKEKIEKKEKP--ETKTLAKEQKKAK------TAEKSEEKTKKEVKGGK 226
Query: 193 SEIVKSPRIECSKTRR 208
E VK + + ++
Sbjct: 227 QEKVKQTAAKVKEVQK 242
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 58.2 bits (139), Expect = 3e-08
Identities = 59/307 (19%), Positives = 147/307 (47%), Gaps = 28/307 (9%)
Query: 522 LNRKFKKEELL--DMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDEEQI 579
L RK ++ +LL QA ++ + + +LQ VEE+ + + EE++
Sbjct: 247 LKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQ----VEENELWNRLNQQQEEKM 302
Query: 580 AKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNK---LEGKDKLTPWEQFL 636
+ + +Q +EK ++ +E E E K ++E E+M + + E ++K+ E+ +
Sbjct: 303 WRQEEKIQEWEEKIQEQEEKIREQEEK----IREQEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 637 EKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPE 696
+K+EK ++R+++ + E+ + ++ E+++ ++ ++ ++ E
Sbjct: 359 WEKEEK--MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE 416
Query: 697 EEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVN 756
E+I + ++ E M ++E KI E + ++++K++ +++E I + ++
Sbjct: 417 EKIREQEKRQEQEAKMWRQEE---------KIREQEEKIREQEKKMWRQEEKIHEQEKIR 467
Query: 757 VNDAR--FQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQELTQAIKKKESE 814
+ R + M+ + + +K K E+ EEK R++E K + I+++E +
Sbjct: 468 EEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQ--EEKIRKQEEKVWRQEEKIREQEEK 525
Query: 815 IEKESQR 821
I ++ ++
Sbjct: 526 IREQEEK 532
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/318 (19%), Positives = 147/318 (46%), Gaps = 38/318 (11%)
Query: 517 ERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGKTKKSQKDDE 576
E+I K +++E + + + + E E EE+++ + + E++ K ++ ++
Sbjct: 328 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 387
Query: 577 EQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFL 636
E+ K R+L + + E+EK ++ + E +E E K + E + K+ E+ +
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQE-------EEKIREQEKRQ-EQEAKMWRQEEKI 439
Query: 637 EKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPE 696
+++EK R + K+ EE E+ E++++ ++ + +
Sbjct: 440 REQEEKIREQEKKMWRQEEKIHEQ-------------EKIREEEKRQEQEEMWRQEEKIH 486
Query: 697 EEIEIERQKAEMALLMMDEDEDSKKH-----FNYNKIVEHQNLSKKKKKQLMKKKELIED 751
E+ EI RQK + M +++E +K KI E + +++++++ +++E I +
Sbjct: 487 EQEEIWRQKEK----MHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIRE 542
Query: 752 DFEVNVNDARF--QAMYTSHLFNLDPSDPNFKKTKAM----EKI--LEEKARQRERKEQE 803
E+ + + Q + D +++ + + EK+ EEK R++E K QE
Sbjct: 543 QEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQE 602
Query: 804 LTQAIKKKESEIEKESQR 821
+ + K+E +I ++ ++
Sbjct: 603 QEEKMWKQEEKIREQEEK 620
Score = 52.4 bits (124), Expect = 2e-06
Identities = 61/349 (17%), Positives = 162/349 (46%), Gaps = 22/349 (6%)
Query: 508 EITWDETDHERITMLNRKFKKEELLDMDFQAYLASSSEDEEEIEEELQGDDGVNVEEDGK 567
E+ W++ + R ++KEE + + + E E+EE++ + + +E+ +
Sbjct: 356 EMMWEKEEKMR-RQEEMMWEKEEKMRRQ-EEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413
Query: 568 TK----KSQKDDEEQIAKYRQLLQVIQEKEKKGKENDMEMEIKWVPGLKESAEEMVKNKL 623
+ + Q+ +EQ AK + + I+E+E+K +E + +M W K +E ++ +
Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKM---WRQEEKIHEQEKIREEE 470
Query: 624 EGKDKLTPWEQFLEKKKEKKRLKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINK 683
+ +++ W Q + ++++ ++K+K +E + V + E+ ++I +
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Query: 684 KSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQNLSKKKKKQLM 743
+ + ++ +EE+ E +K + +E+ K+ +K+ + +++++++
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEE---KRQEQEDKMWRQEEKIREQEEKVW 587
Query: 744 KKKELIEDDFEVNVNDARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQRERKEQE 803
+++E I + E + + K + EKI E++ + RE ++E
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKI-----REQEEKIQEQEEKIREQEEKIRE--QEE 640
Query: 804 LTQAIKKKESEIEK---ESQRKSIDPALSMLIKSIKTKTEQFQARKKQK 849
+TQ ++K E E+ E + K + +M + K + ++ + R++++
Sbjct: 641 MTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEE 689
Score = 52.0 bits (123), Expect = 2e-06
Identities = 64/339 (18%), Positives = 154/339 (45%), Gaps = 39/339 (11%)
Query: 543 SSEDEEEI---EEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEKEKKGKEN 599
+ + EE++ EE++Q + E++ K ++ ++ EQ K R+ +++ EKE+K +
Sbjct: 295 NQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ 354
Query: 600 DMEMEIKWVPGLK-ESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKR-------------- 644
+ E+ W K EEM+ K ++K+ E+ + +K+EK R
Sbjct: 355 E---EMMWEKEEKMRRQEEMMWEK---EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
Query: 645 ---LKRKQKALAEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEI 701
+++++ + E+ +E + + + E+ ++I +K + ++ +E+I
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 702 ERQKAEMALLMMDED---EDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVN 758
E ++ E + E+ E + K+ E + +K+++++ +++E I + E
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 759 DARFQAMYTSHLFNLDPSDPNFKKTKAMEKILEEKARQ--------RERKEQELTQAIKK 810
+ + +K EKI EE+ RQ +E K +E + + +
Sbjct: 529 QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWR 588
Query: 811 KESEI-EKESQRKSIDPALSMLIKSIKTKTEQFQARKKQ 848
+E +I E+E +R+ + + + I+ + E+ Q ++++
Sbjct: 589 QEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEK 627
Score = 44.3 bits (103), Expect = 5e-04
Identities = 95/591 (16%), Positives = 232/591 (39%), Gaps = 70/591 (11%)
Query: 178 DSSLEEKQRTLDSGTSEIVKSPRIECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKD 237
++ L+EK + ++S SEI ++ + +R+++ L+ + + D
Sbjct: 223 NAKLQEKLQLVESEKSEI----QLNVKELKRKLERAKLLLPQQQLQA----------EAD 268
Query: 238 ALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEE---EDEDEDSEDDD 294
L ++ +SVS + ENE+ + ++ +E+ E EE E E++ E ++
Sbjct: 269 HLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEE 328
Query: 295 KSDSGPDLARGKGNIETSSEDEDDTADLFPEESGFEHAWRELDKDAPRADEITRRLAVCN 354
K + R + + E++ + E E R ++ +E RR
Sbjct: 329 KIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK--EEKMRRQEEMMWEKEEKMRRQE--E 384
Query: 355 MDWDRL-KAKDLLALFNSFKPKGGVIFSVKIYPSEFGKERMKEEQVQGPVELLSIPEDAP 413
M W++ K ++L K++ E +E+ ++ Q + + ++
Sbjct: 385 MMWEKEEKIREL---------------EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 414 EKDWTSREKLRDYQFKRLKYYYAVVDCDSPETASKIYEDCDGLEFESSCSFIDLRFIPDD 473
K W EK+R+ + K E K++ + + + + R ++
Sbjct: 430 AKMWRQEEKIREQEEK------------IREQEKKMWRQEEKIHEQEKIREEEKRQEQEE 477
Query: 474 ITFDDEPKDVASEVNLTAYKPKYFTSAAMGTSTVEITWDETDHERITMLNRKFKKEELLD 533
+ +E + + + K K E W + E+I K +++E
Sbjct: 478 MWRQEEK--IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQ--EEKIREQEEKIREQE--- 530
Query: 534 MDFQAYLASSSEDEEEI-EEELQGDDGVNVEEDGKTKKSQKDDEEQIAKYRQLLQVIQEK 592
EE+I E+E + + E K + +K E++ +RQ ++ +++
Sbjct: 531 -------EKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQE 583
Query: 593 EKKGKENDMEMEIKWVPGLKESAEEMVKNKLEGKDKLTPWEQFLEKKKEKKRLKRKQKAL 652
EK ++ + E +E +E + + ++K+ E+ +++++EK R + ++
Sbjct: 584 EKVWRQEEKIRE------QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637
Query: 653 AEEASEEELPSDVDLNDPYFAEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLM 712
EE ++E+ + + +E K + + + E++I + +K M
Sbjct: 638 QEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEM 697
Query: 713 MDEDEDSKKHFNYNKIVEHQNLSKKKKKQLMKKKELIEDDFEVNVNDARFQ 763
M E E+ + + + ++++K +++++ E + + + + Q
Sbjct: 698 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,718,666
Number of Sequences: 37866
Number of extensions: 1745935
Number of successful extensions: 42150
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 755
Number of HSP's successfully gapped in prelim test: 1119
Number of HSP's that attempted gapping in prelim test: 12129
Number of HSP's gapped (non-prelim): 14165
length of query: 851
length of database: 18,247,518
effective HSP length: 111
effective length of query: 740
effective length of database: 14,044,392
effective search space: 10392850080
effective search space used: 10392850080
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.