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Search of human proteins with 18087817
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18087817 coiled-coil domain containing 34 isoform 2 [Homo
sapiens]
(229 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18087817 coiled-coil domain containing 34 isoform 2 [Homo sap... 470 e-133
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 417 e-117
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 1e-05
gi|210032580 SET domain containing 1B [Homo sapiens] 47 1e-05
gi|88759339 aster-associated protein [Homo sapiens] 47 1e-05
gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo s... 46 3e-05
gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo s... 46 3e-05
gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo s... 46 3e-05
gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo s... 46 3e-05
gi|63252866 osteosarcoma amplified 9 isoform 2 precursor [Homo s... 45 4e-05
gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo sa... 45 4e-05
gi|34878777 ring finger protein 20 [Homo sapiens] 44 9e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 44 9e-05
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens] 44 1e-04
gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo s... 44 2e-04
gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo s... 44 2e-04
gi|83281438 eukaryotic translation initiation factor 3, subunit ... 43 3e-04
gi|13027602 DDRGK domain containing 1 [Homo sapiens] 42 3e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 42 4e-04
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 41 7e-04
gi|148746195 trichohyalin [Homo sapiens] 41 7e-04
gi|55956788 nucleolin [Homo sapiens] 41 0.001
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 41 0.001
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 41 0.001
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 40 0.001
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 40 0.001
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 40 0.001
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 40 0.002
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 40 0.002
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 40 0.002
>gi|18087817 coiled-coil domain containing 34 isoform 2 [Homo
sapiens]
Length = 229
Score = 470 bits (1210), Expect = e-133
Identities = 229/229 (100%), Positives = 229/229 (100%)
Query: 1 MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS 60
MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS
Sbjct: 1 MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS 60
Query: 61 NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS
Sbjct: 61 NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE
Sbjct: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
Query: 181 REKRKIIAEEKHKEWVQKKNEQVRRGKWIHTLTSLLQNISSYYTSLPRF 229
REKRKIIAEEKHKEWVQKKNEQVRRGKWIHTLTSLLQNISSYYTSLPRF
Sbjct: 181 REKRKIIAEEKHKEWVQKKNEQVRRGKWIHTLTSLLQNISSYYTSLPRF 229
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
Length = 373
Score = 417 bits (1073), Expect = e-117
Identities = 203/205 (99%), Positives = 204/205 (99%)
Query: 1 MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS 60
MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS
Sbjct: 1 MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCS 60
Query: 61 NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS
Sbjct: 61 NSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCAS 120
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE
Sbjct: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
Query: 181 REKRKIIAEEKHKEWVQKKNEQVRR 205
REKRKIIAEEKHKEWVQKKNEQ R+
Sbjct: 181 REKRKIIAEEKHKEWVQKKNEQKRK 205
Score = 33.5 bits (75), Expect = 0.16
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 11/96 (11%)
Query: 114 ELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLE 173
E++ A+ ++E E QE+ K+ ++ W K EE +R + + +E QQ E
Sbjct: 214 EMEEKAAKELEKEYLQEKAKE---------KYQEWLKKKNAEECERKKKEKEKEKQQQAE 264
Query: 174 --KRKEMEEREKRKIIAEEKHKEWVQKKNEQVRRGK 207
++KE+ E++ ++ + KHK K+ GK
Sbjct: 265 IQEKKEIAEKKFQEWLENAKHKPRPAAKSYGYANGK 300
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 47.4 bits (111), Expect = 1e-05
Identities = 33/125 (26%), Positives = 64/125 (51%), Gaps = 12/125 (9%)
Query: 82 GDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQ---VRLP 138
GD E+ ++V+ + H SE + L +E Q S++ E E +EE+++ VR
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265
Query: 139 ESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQK 198
E KE+EE + Q++ EE ++ +K K+ EE ++++ + EEK + ++
Sbjct: 2266 EEER---------KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEE 2316
Query: 199 KNEQV 203
+ E +
Sbjct: 2317 ETESL 2321
Score = 45.4 bits (106), Expect = 4e-05
Identities = 37/127 (29%), Positives = 68/127 (53%), Gaps = 8/127 (6%)
Query: 83 DGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQV---ESENNQEEQKQVRLPE 139
D E+E +++EE + + + RG + + S+QV ESE + E+ + L E
Sbjct: 2177 DDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE 2236
Query: 140 SRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKI--IAEEKHKEWVQ 197
+ +E+EER+ + + EE+ ++ E+RKE EE E++++ EEK K+ +
Sbjct: 2237 LEK---QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKE 2293
Query: 198 KKNEQVR 204
KK E+V+
Sbjct: 2294 KKKEEVQ 2300
Score = 42.0 bits (97), Expect = 4e-04
Identities = 37/142 (26%), Positives = 69/142 (48%), Gaps = 18/142 (12%)
Query: 60 SNSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCA 119
S SLL L Q E++ + E+EE+ ++EE +E+ E E +G
Sbjct: 2227 SEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKE---------EEEG-E 2276
Query: 120 STQVESENNQEEQKQVRLPESRLTPWEVWFIGKE----KEERDRLQLKALEE----LNQQ 171
QVE E ++++K+ + + E F KE +EE + L + EE L ++
Sbjct: 2277 EKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEE 2336
Query: 172 LEKRKEMEEREKRKIIAEEKHK 193
+++ KE+ ++EK+ + E++ K
Sbjct: 2337 VDREKEILKKEKQFKLQEQRRK 2358
Score = 30.8 bits (68), Expect = 1.0
Identities = 31/132 (23%), Positives = 55/132 (41%), Gaps = 30/132 (22%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
+DEE+V EE+V + + E +V E + QEE K R+ R
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTE--------------EQRHIQEEHKWARIHRKRAR- 1583
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKR----KIIAEEKHK-----EW 195
++K ++ +L EE Q E++ EER+ KI +++ ++
Sbjct: 1584 ------AEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKF 1637
Query: 196 VQKKNEQVRRGK 207
QK+ +RG+
Sbjct: 1638 AQKEETLAQRGE 1649
Score = 30.4 bits (67), Expect = 1.3
Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 6/84 (7%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKEKEE--RDRLQLKALEELNQQLEKRKEMEEREK 183
E +E K+++ E + WE K KE+ +D ++ EE++++ E++++ E+
Sbjct: 1507 EEMLQEDKKLKWEEWKQV-WENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQ 1565
Query: 184 RKIIAEEKHKEWVQKKNEQVRRGK 207
R I +E+HK W + ++ R K
Sbjct: 1566 RHI--QEEHK-WARIHRKRARAEK 1586
Score = 30.4 bits (67), Expect = 1.3
Identities = 44/163 (26%), Positives = 70/163 (42%), Gaps = 13/163 (7%)
Query: 69 PLGHQSFQFDEDDGDGEDEEDVDDEEDV---DEDAHDSEAK-VASLRGMELQGCASTQVE 124
P Q+ + E + E EE D E++ +E+ + E K V + + + A
Sbjct: 1701 PQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQR 1760
Query: 125 SENNQEEQKQVRLPESRLTPWEVWFIGKEK--EERDRLQLKA--LEELNQQLEKRKE--- 177
+ ++EE K + E + E KEK EE +RL K L E +L +++E
Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWI 1820
Query: 178 --MEEREKRKIIAEEKHKEWVQKKNEQVRRGKWIHTLTSLLQN 218
MEE K K+I +K +KKN + K +LL N
Sbjct: 1821 NSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYN 1863
Score = 29.3 bits (64), Expect = 2.9
Identities = 30/140 (21%), Positives = 67/140 (47%), Gaps = 14/140 (10%)
Query: 85 EDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E+++ + +EE+ E + E K+A + +Q E EE++++
Sbjct: 1744 EEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKRE 1803
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQ---LEKRKEMEEREKRKIIAEEKHKEWVQ 197
+L ++ K ++R+R + ++EEL + L ++K + + +K +A+EK K +
Sbjct: 1804 QLIEKKM----KLAQKRERW-INSMEELTKNKMILYQKKNLAQEKKN--LAQEKEKLAQR 1856
Query: 198 KKNEQVRRGKWIHTLTSLLQ 217
K+N + + H+ L+Q
Sbjct: 1857 KENLLYNKERLTHSKKQLVQ 1876
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 47.4 bits (111), Expect = 1e-05
Identities = 43/172 (25%), Positives = 76/172 (44%), Gaps = 15/172 (8%)
Query: 23 RPRSRPSSDS-CSVPMTGARGQGLEVVRSPSPPLPLSCSNSTRSLLSPLGHQSFQFDEDD 81
R R R +D+ C + +G G+ R P+ PL L S Q +E++
Sbjct: 996 RERDRDMADTPCELAKRDPKGVGVR--RRPARPLELDSGGEEDEKESLSEEQESTEEEEE 1053
Query: 82 GDGEDEEDVDDEEDV---DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLP 138
+ E+EE+ DD++D DE +D E S AS + E ++++EE +
Sbjct: 1054 AEEEEEEEDDDDDDSDDRDESENDDEDTALSE--------ASEKDEGDSDEEETVSIVTS 1105
Query: 139 ESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
++ T E E + E+ +++ R+E EE E+ +++AEE
Sbjct: 1106 KAEATSSSESSESSEFESSSESSPSSSED-EEEVVAREEEEEEEEEEMVAEE 1156
Score = 32.0 bits (71), Expect = 0.45
Identities = 25/111 (22%), Positives = 52/111 (46%), Gaps = 10/111 (9%)
Query: 86 DEEDVDDEEDVDEDAHDSEAKVASL--RGMELQGCASTQVESENNQEEQKQVRLPESRLT 143
DEED + E + D D D+ ++A +G+ ++ + +E ++ EE ++ L E + +
Sbjct: 988 DEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQES 1047
Query: 144 PWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKE 194
E +E+EE D + + + R E E ++ ++E K+
Sbjct: 1048 TEEEEEAEEEEEEED--------DDDDDSDDRDESENDDEDTALSEASEKD 1090
>gi|88759339 aster-associated protein [Homo sapiens]
Length = 647
Score = 47.0 bits (110), Expect = 1e-05
Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 122 QVESENN--QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEME 179
++ESEN Q EQK+ E L +E W KEKE + K LEE N K+K E
Sbjct: 448 RIESENLRIQNEQKKAAKREEALASFEAWKAMKEKEAKKIAAKKRLEEKN----KKKTEE 503
Query: 180 EREKRKIIAEEKHKEWVQKKNEQVR 204
E RK A + ++W +KK E ++
Sbjct: 504 ENAARKGEALQAFEKWKEKKMEYLK 528
Score = 33.9 bits (76), Expect = 0.12
Identities = 22/84 (26%), Positives = 45/84 (53%), Gaps = 12/84 (14%)
Query: 125 SENNQEEQKQVRLPESRLTPWEVWFIGKE----KEERDRLQLKALEELNQQLEKRKEMEE 180
++ +EE+ + LT E W KE ++E++++ K EEL KR E ++
Sbjct: 540 AKKQKEEETVAEKKKDNLTAVEKWNEKKEAFFKQKEKEKINEKRKEEL-----KRAEKKD 594
Query: 181 REKRKIIAEEKHKEWVQKKNEQVR 204
++K+ I ++++W++ K +Q R
Sbjct: 595 KDKQAI---NEYEKWLENKEKQER 615
>gi|154354972 phosphatase and actin regulator 2 isoform 4 [Homo
sapiens]
Length = 554
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 14/135 (10%)
Query: 71 GHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
GH+ +Q ++ D DG D++ED DED A + +R + S+ E
Sbjct: 354 GHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELE 413
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
++ ++ +EER ++ + +L ++L +R EE E+R I+ ++
Sbjct: 414 DKNILQ--------------RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQK 459
Query: 191 KHKEWVQKKNEQVRR 205
+E + K E RR
Sbjct: 460 NEEEEQEAKMELKRR 474
>gi|154354974 phosphatase and actin regulator 2 isoform 3 [Homo
sapiens]
Length = 634
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 14/135 (10%)
Query: 71 GHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
GH+ +Q ++ D DG D++ED DED A + +R + S+ E
Sbjct: 434 GHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELE 493
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
++ ++ +EER ++ + +L ++L +R EE E+R I+ ++
Sbjct: 494 DKNILQ--------------RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQK 539
Query: 191 KHKEWVQKKNEQVRR 205
+E + K E RR
Sbjct: 540 NEEEEQEAKMELKRR 554
>gi|154354970 phosphatase and actin regulator 2 isoform 2 [Homo
sapiens]
Length = 565
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 14/135 (10%)
Query: 71 GHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
GH+ +Q ++ D DG D++ED DED A + +R + S+ E
Sbjct: 365 GHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELE 424
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
++ ++ +EER ++ + +L ++L +R EE E+R I+ ++
Sbjct: 425 DKNILQ--------------RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQK 470
Query: 191 KHKEWVQKKNEQVRR 205
+E + K E RR
Sbjct: 471 NEEEEQEAKMELKRR 485
>gi|154354968 phosphatase and actin regulator 2 isoform 1 [Homo
sapiens]
Length = 645
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 14/135 (10%)
Query: 71 GHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
GH+ +Q ++ D DG D++ED DED A + +R + S+ E
Sbjct: 445 GHREYQANDSDSDGPILYTDDEDEDEDEDGSGESALASKIRRRDTLAIKLGNRPSKKELE 504
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
++ ++ +EER ++ + +L ++L +R EE E+R I+ ++
Sbjct: 505 DKNILQ--------------RTSEEERQEIRQQIGTKLVRRLSQRPTTEELEQRNILKQK 550
Query: 191 KHKEWVQKKNEQVRR 205
+E + K E RR
Sbjct: 551 NEEEEQEAKMELKRR 565
>gi|63252866 osteosarcoma amplified 9 isoform 2 precursor [Homo
sapiens]
Length = 612
Score = 45.4 bits (106), Expect = 4e-05
Identities = 35/132 (26%), Positives = 66/132 (50%), Gaps = 17/132 (12%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGC--------ASTQVESEN 127
+++ GD E + ++++EED DED + E + L EL+G ++V++
Sbjct: 401 EKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGM 460
Query: 128 NQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKII 187
+E + ++ E L P + K++ ERDR L LN+ + K +EE++ +++
Sbjct: 461 ERELENIIQETEKELDPDGL----KKESERDRAMLALTSTLNKLI---KRLEEKQSPELV 513
Query: 188 AEEKHKEWVQKK 199
+ K K V KK
Sbjct: 514 KKHKKKRVVPKK 525
>gi|5803109 osteosarcoma amplified 9 isoform 1 precursor [Homo
sapiens]
Length = 667
Score = 45.4 bits (106), Expect = 4e-05
Identities = 35/132 (26%), Positives = 66/132 (50%), Gaps = 17/132 (12%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGC--------ASTQVESEN 127
+++ GD E + ++++EED DED + E + L EL+G ++V++
Sbjct: 401 EKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSEVKAGM 460
Query: 128 NQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKII 187
+E + ++ E L P + K++ ERDR L LN+ + K +EE++ +++
Sbjct: 461 ERELENIIQETEKELDPDGL----KKESERDRAMLALTSTLNKLI---KRLEEKQSPELV 513
Query: 188 AEEKHKEWVQKK 199
+ K K V KK
Sbjct: 514 KKHKKKRVVPKK 525
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 44.3 bits (103), Expect = 9e-05
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 30/132 (22%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E E++ D +D ++ HD K E + ++E + QE QK+++L
Sbjct: 599 ESEKERDSAKDKEKGKHDDGRK------KEAEIIKQLKIELKKAQESQKEMKLLLDM--- 649
Query: 145 WEVWFIGKEKEERDRLQLKALE-----ELNQQLEKRKEMEEREK------------RKII 187
+ KE+RD++QL A E EL ++ K++E++EK RKI
Sbjct: 650 ----YRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIR 705
Query: 188 AEEKHKEWVQKK 199
A E+ E++QKK
Sbjct: 706 AVEEQIEYLQKK 717
Score = 32.7 bits (73), Expect = 0.26
Identities = 17/50 (34%), Positives = 31/50 (62%), Gaps = 1/50 (2%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
+++EER+R + + E ++ EK KE EREK+K+ EK ++ + K +
Sbjct: 564 RDEEERERERREKEREREREREKEKE-REREKQKLKESEKERDSAKDKEK 612
Score = 30.4 bits (67), Expect = 1.3
Identities = 24/122 (19%), Positives = 62/122 (50%), Gaps = 19/122 (15%)
Query: 87 EEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWE 146
E+ D+ ++ D+ D ++ ++ + + + +++S+ ++EE+++ R
Sbjct: 527 EDPKDEPAELKPDSEDLSSQSSASKASQED---ANEIKSKRDEEERERER---------- 573
Query: 147 VWFIGKEKE-ERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQVRR 205
+EKE ER+R + K E ++ + ++ +ER+ K + KH + +K+ E +++
Sbjct: 574 -----REKEREREREREKEKEREREKQKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQ 628
Query: 206 GK 207
K
Sbjct: 629 LK 630
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 44.3 bits (103), Expect = 9e-05
Identities = 39/146 (26%), Positives = 69/146 (47%), Gaps = 8/146 (5%)
Query: 70 LGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRG-MELQGCASTQVESENN 128
+ H +ED E E + E+ + + + K+A R +E + A+ Q
Sbjct: 251 ISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERRE 310
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEK---EERDRL---QLKALEELNQ-QLEKRKEMEER 181
EE++++R E R +EK EER R+ + +A EE + + E+++ EER
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370
Query: 182 EKRKIIAEEKHKEWVQKKNEQVRRGK 207
++ + EEK K QK+N+Q+ K
Sbjct: 371 QRARAEEEEKAKVEEQKRNKQLEEKK 396
Score = 32.7 bits (73), Expect = 0.26
Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 6/102 (5%)
Query: 99 DAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEK---- 154
D ++E G L+ + E+E+ + E+ + + E+ L E+ +E+
Sbjct: 520 DTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVL 579
Query: 155 --EERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKE 194
EE+ R Q +A +L ++ EKR+ EE E+R+ A EK ++
Sbjct: 580 EEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621
Score = 30.4 bits (67), Expect = 1.3
Identities = 27/100 (27%), Positives = 54/100 (54%), Gaps = 8/100 (8%)
Query: 108 ASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEE 167
AS+ E +G + QVE+ EE ++ R E+ +E K+K++ L+L+ L++
Sbjct: 517 ASVDTKEAEG--APQVEAGKRLEELRR-RRGETESEEFEKL---KQKQQEAALELEELKK 570
Query: 168 LNQQLEKRKEMEEREKRKIIAEEKHKEWVQKK--NEQVRR 205
++ K E EE+ +++ A+ K +E +K+ E++ R
Sbjct: 571 KREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIER 610
Score = 28.5 bits (62), Expect = 5.0
Identities = 34/139 (24%), Positives = 64/139 (46%), Gaps = 22/139 (15%)
Query: 84 GEDEEDVDDEEDVDEDAHDSEAKVASLRGMEL------------QGCASTQVESENNQEE 131
GE++ +V EE E E V SL+ ++ QG + +E+
Sbjct: 204 GENQVEVMVEEKTTES--QEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEED 261
Query: 132 QKQVRLPESRLTPWEVWFIGKEKEER---DRLQLKALEELNQQLEKRKEMEEREKRKIIA 188
+++ +RL E I E++++ +R +++A E+ Q +R+E EERE +
Sbjct: 262 KERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERE---RMR 318
Query: 189 EEKHK--EWVQKKNEQVRR 205
EE+ + E Q+ E+ +R
Sbjct: 319 EEEKRAAEERQRIKEEEKR 337
>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
Length = 439
Score = 43.9 bits (102), Expect = 1e-04
Identities = 36/135 (26%), Positives = 67/135 (49%), Gaps = 11/135 (8%)
Query: 74 SFQFDEDDGDGEDEEDVDDEE------DVDEDAHDSEAKVASLRGMELQGCASTQVESEN 127
+++ + +D E+EE++DDEE + + A + + + + +E +G + + ESE+
Sbjct: 124 AWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESES 183
Query: 128 NQEEQKQVR-LPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK--R 184
EE E RL P V+ K++ + +AL++ + E ++ EER K
Sbjct: 184 EYEEYTDSEDEMEPRLKP--VFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTL 241
Query: 185 KIIAEEKHKEWVQKK 199
KI+ EE KE + K
Sbjct: 242 KIVEEETKKELEENK 256
Score = 31.2 bits (69), Expect = 0.77
Identities = 21/93 (22%), Positives = 45/93 (48%), Gaps = 22/93 (23%)
Query: 93 EEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGK 152
EE+ ++ +++ +A+L + + EN++EE +E W + +
Sbjct: 245 EEETKKELEENKRSLAALDALN--------TDDENDEEE-------------YEAWKVRE 283
Query: 153 EKE-ERDRLQLKALEELNQQLEKRKEMEEREKR 184
K +RDR +ALE+ ++E+ + + E E+R
Sbjct: 284 LKRIKRDREDREALEKEKAEIERMRNLTEEERR 316
>gi|63252870 osteosarcoma amplified 9 isoform 4 precursor [Homo
sapiens]
Length = 652
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/124 (26%), Positives = 59/124 (47%), Gaps = 16/124 (12%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQEEQKQV 135
+++ GD E + ++++EED DED + E + L EL+G E +K++
Sbjct: 401 EKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKEL 460
Query: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
P+ K++ ERDR L LN+ + K +EE++ +++ + K K
Sbjct: 461 D-PDGL----------KKESERDRAMLALTSTLNKLI---KRLEEKQSPELVKKHKKKRV 506
Query: 196 VQKK 199
V KK
Sbjct: 507 VPKK 510
>gi|63252868 osteosarcoma amplified 9 isoform 3 precursor [Homo
sapiens]
Length = 597
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/124 (26%), Positives = 59/124 (47%), Gaps = 16/124 (12%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQEEQKQV 135
+++ GD E + ++++EED DED + E + L EL+G E +K++
Sbjct: 401 EKERGDPERQREMEEEEDEDEDEDEDEDERQLLGEFEKELEGILLPSDRDRLRSETEKEL 460
Query: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
P+ K++ ERDR L LN+ + K +EE++ +++ + K K
Sbjct: 461 D-PDGL----------KKESERDRAMLALTSTLNKLI---KRLEEKQSPELVKKHKKKRV 506
Query: 196 VQKK 199
V KK
Sbjct: 507 VPKK 510
>gi|83281438 eukaryotic translation initiation factor 3, subunit 1
alpha, 35kDa [Homo sapiens]
Length = 258
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/99 (30%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
Query: 80 DDGDGEDE-EDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLP 138
D +GEDE EDV D D D+D EA+V + + + +++ + Q++++Q +
Sbjct: 37 DRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIK 96
Query: 139 ESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE 177
+ P E + E++ D+L+LK L+E LE KE
Sbjct: 97 KRLEEPEEPKVLTPEEQLADKLRLKKLQE-ESDLELAKE 134
Score = 28.1 bits (61), Expect = 6.5
Identities = 13/37 (35%), Positives = 23/37 (62%)
Query: 166 EELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQ 202
+E ++ E + E++ EK+KI + K KE QKK ++
Sbjct: 57 DEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQE 93
>gi|13027602 DDRGK domain containing 1 [Homo sapiens]
Length = 314
Score = 42.4 bits (98), Expect = 3e-04
Identities = 36/125 (28%), Positives = 62/125 (49%), Gaps = 24/125 (19%)
Query: 81 DGDGEDEEDV---DDEEDVDEDAH---DSEAKVASLRGMELQGCASTQVESENNQEEQKQ 134
+ D +EE V +EE V++ A + LR +E + Q E+E + E+++
Sbjct: 87 EADENEEEAVILAQEEEGVEKPAETHLSGKIGAKKLRKLEEKQARKAQREAEEAEREERK 146
Query: 135 VRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKE 194
RL R W K++EER RL+ E++KE EER+ R+ A+ +H+E
Sbjct: 147 -RLESQREAEW------KKEEERLRLE-----------EEQKEEEERKAREEQAQREHEE 188
Query: 195 WVQKK 199
+++ K
Sbjct: 189 YLKLK 193
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 42.0 bits (97), Expect = 4e-04
Identities = 37/132 (28%), Positives = 61/132 (46%), Gaps = 15/132 (11%)
Query: 73 QSFQFDEDDGD-GEDEEDV-DDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
Q Q E +G GE EE + + EE + + + +R E Q Q E QE
Sbjct: 190 QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQ--MGEQEEQVQKQE 247
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
EQ Q + + R ++EE+ R Q + + E +Q+ K+KE E+E++ EE
Sbjct: 248 EQVQKQEEQMR-----------KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEE 296
Query: 191 KHKEWVQKKNEQ 202
+ +E ++ EQ
Sbjct: 297 QMREQEEQMREQ 308
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/136 (25%), Positives = 66/136 (48%), Gaps = 10/136 (7%)
Query: 70 LGHQSFQFDEDDGD-GEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENN 128
+G Q Q E + GE EE + +E+ + + K G + + Q + E
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE---QVQKQEEQV 250
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIA 188
Q++++Q+R E ++ E +E+EE+ Q + E+ Q E+ ++M E+E++
Sbjct: 251 QKQEEQMRKQEEQMREQEEQM--REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ 308
Query: 189 EEKHKEWVQKKNEQVR 204
EE+ +E + EQ+R
Sbjct: 309 EEQMRE----QEEQMR 320
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/135 (22%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQ 132
Q Q E +G ++E E++ + E +V G + + + +E++
Sbjct: 127 QEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 184
Query: 133 KQVRLPESRLTPWEVWFIGKEKE--ERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
QVR E ++ E +E++ E++ K E++ +Q E+ ++ EE+ + +
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 191 KHKEWVQKKNEQVRR 205
K +E VQK+ EQ+R+
Sbjct: 245 KQEEQVQKQEEQMRK 259
Score = 40.0 bits (92), Expect = 0.002
Identities = 27/130 (20%), Positives = 67/130 (51%), Gaps = 6/130 (4%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
++++ E EE + +++ E + + +R E Q + + E +E+++Q+R
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ----MREQEEQMREQEEQMRE 321
Query: 138 PESRLTPWE--VWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
E ++ E +W ++ E+ K E++ +Q E+ ++ EE+ +++ K +E
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQ 381
Query: 196 VQKKNEQVRR 205
++K+ EQ+R+
Sbjct: 382 MRKQEEQMRK 391
Score = 37.4 bits (85), Expect = 0.011
Identities = 32/134 (23%), Positives = 63/134 (47%), Gaps = 18/134 (13%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQE 130
Q Q E +G ++E E++ + E +V G E +G Q E QE
Sbjct: 155 QEGQVREQEGQVREQEGQVREQE--GQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQE 212
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
EQ Q + + E+EE+ R Q + + E +Q++K++E ++++ ++
Sbjct: 213 EQMQKQEEQMG-----------EQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM---R 258
Query: 191 KHKEWVQKKNEQVR 204
K +E ++++ EQ+R
Sbjct: 259 KQEEQMREQEEQMR 272
Score = 37.0 bits (84), Expect = 0.014
Identities = 29/135 (21%), Positives = 63/135 (46%), Gaps = 8/135 (5%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQ 132
Q Q ++++ GE EE + ++E+ + + +R E Q Q E QEEQ
Sbjct: 281 QKEQTEQEEQTGEQEEQMREQEEQMREQEEQ------MREQEEQ--MREQEEQMGKQEEQ 332
Query: 133 KQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKH 192
+ + ++W ++ E++ K E++ +Q E+ ++ EE+ +++ K
Sbjct: 333 MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
Query: 193 KEWVQKKNEQVRRGK 207
+E + ++ EQ+ K
Sbjct: 393 EEQMGEQKEQMGEQK 407
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 41.2 bits (95), Expect = 7e-04
Identities = 30/131 (22%), Positives = 65/131 (49%), Gaps = 3/131 (2%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
++++ +GE++E +E + E K R E + + E + + E+++ R
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERE-RKEERKREERKERERKKEEREKERERK 161
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ 197
+ +V +E++E++R + K E + E++KE E +E+R+ E K KE +
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRER--NRKERKKERERKERRERKKERKKKEERK 219
Query: 198 KKNEQVRRGKW 208
K+ ++ R+ W
Sbjct: 220 KERQKDRQTNW 230
Score = 32.3 bits (72), Expect = 0.35
Identities = 18/60 (30%), Positives = 36/60 (60%), Gaps = 4/60 (6%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ----KKNEQVRRGK 207
+EK +R+R + + E ++ + ++ EERE++K E+++KE + KK E+ RG+
Sbjct: 66 REKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGR 125
Score = 31.6 bits (70), Expect = 0.59
Identities = 16/56 (28%), Positives = 35/56 (62%), Gaps = 2/56 (3%)
Query: 152 KEKEERDRLQLKALEELNQ--QLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQVRR 205
++KEER+R + + +E + + EKRK+ E++E+ + E K +E +++ + R+
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Score = 30.8 bits (68), Expect = 1.0
Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 153 EKEERDR-LQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQVRRGK 207
E ER+R ++ + + ++ E++KE EREKRK E++ K KK ++ R K
Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKK 92
Score = 29.3 bits (64), Expect = 2.9
Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 23/124 (18%)
Query: 87 EEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWE 146
EE + E +E + E K R + G + + + +E +K+ R + R
Sbjct: 142 EERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER----- 196
Query: 147 VWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQK---KNEQV 203
K+ER+R +E ++ ++RK+ EER+K + +++ W +K K E+
Sbjct: 197 -------KKERER------KERRERKKERKKKEERKKER--QKDRQTNWREKERGKRERK 241
Query: 204 RRGK 207
R K
Sbjct: 242 ERKK 245
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 41.2 bits (95), Expect = 7e-04
Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 18/118 (15%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E+E+ ++E + + E ++ L EL+ E +EEQ+Q RL +
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKLERQELR--------RERQEEEQQQQRLRREQQL- 306
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQ 202
+ K+E +R + + EE +Q E+R++ EER ++++ E++ + Q + EQ
Sbjct: 307 -------RRKQEEERREQQ--EERREQQERREQQEERREQQLRREQEERREQQLRREQ 355
Score = 39.7 bits (91), Expect = 0.002
Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 1/83 (1%)
Query: 122 QVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER 181
Q E + QE+Q++ R E R W + +E++ R R L A L +QL K +++ +
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRR-RHTLYAKPALQEQLRKEQQLLQE 908
Query: 182 EKRKIIAEEKHKEWVQKKNEQVR 204
E+ ++ EE+ K Q++ Q R
Sbjct: 909 EEEELQREEREKRRRQEQERQYR 931
Score = 39.3 bits (90), Expect = 0.003
Identities = 33/129 (25%), Positives = 64/129 (49%), Gaps = 9/129 (6%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQEEQKQVRLPESRL 142
E+EE++ EE + E + + E + + E QE ++Q R + +L
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR-KDKKL 966
Query: 143 TPWEVWFIGKEKEERDRLQ----LKALEELNQQLEK--RKEMEEREKRKIIAEEKHKEWV 196
E +G+E E+R R + + EEL Q+ E+ R+E E+R +++ + + K+ +
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 197 QKKNEQVRR 205
Q++ EQ+ R
Sbjct: 1027 QQEEEQLLR 1035
Score = 39.3 bits (90), Expect = 0.003
Identities = 34/138 (24%), Positives = 69/138 (50%), Gaps = 9/138 (6%)
Query: 76 QFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQEEQK 133
Q+ E++ ++EE + EE + E + + E + + E QE ++
Sbjct: 1049 QYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERER 1108
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRLQL----KALEELNQQLEK--RKEMEEREKRKII 187
Q R E L E + +E+E+R R +L + EE+ Q+ E+ R+E E+R ++++
Sbjct: 1109 QCR-EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 188 AEEKHKEWVQKKNEQVRR 205
+ + +E +Q++ EQ+ R
Sbjct: 1168 RQYREEEELQQEEEQLLR 1185
Score = 38.9 bits (89), Expect = 0.004
Identities = 31/104 (29%), Positives = 52/104 (50%), Gaps = 13/104 (12%)
Query: 111 RGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQ 170
R ELQ + + +EEQ+ R W+ + +EK ER R +L A L +
Sbjct: 742 RESELQWQEEERAHRQQQEEEQR-------RDFTWQ--WQAEEKSERGRQRLSARPPLRE 792
Query: 171 QLEKRKEMEEREKR--KIIAEEKHKEWVQKKNEQVRRGKWIHTL 212
Q E++ EER++R + + EE+ KE Q++ ++ R K + L
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKE--QRRRQRREREKELQFL 834
Score = 38.1 bits (87), Expect = 0.006
Identities = 31/134 (23%), Positives = 64/134 (47%), Gaps = 10/134 (7%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMEL--QGCASTQVESENNQE 130
Q Q+ E++ ++EE + EE + E + + ++ + + E QE
Sbjct: 926 QERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQE 985
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
+K+ R E L E + +E+E+R R +E +Q K+ E+++ E+ +++ EE
Sbjct: 986 REKKYR-EEEELQQEEEQLLREEREKRRR------QEWERQYRKKDELQQ-EEEQLLREE 1037
Query: 191 KHKEWVQKKNEQVR 204
+ K +Q++ Q R
Sbjct: 1038 REKRRLQERERQYR 1051
Score = 37.7 bits (86), Expect = 0.008
Identities = 28/122 (22%), Positives = 64/122 (52%), Gaps = 9/122 (7%)
Query: 91 DDEEDVDEDAHDSEAKVASLRGM--ELQGCASTQVESENNQEEQKQVRLPESRLTPW-EV 147
+ EE+ E H+ E + L+ E + + E+E +++E+++ +L + E
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 148 WFIGKEKEERDRLQ------LKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
W +E+E R++ + + EE +Q KR+E EER ++++ +E++ + +++ E
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 202 QV 203
Q+
Sbjct: 548 QL 549
Score = 37.4 bits (85), Expect = 0.011
Identities = 28/88 (31%), Positives = 49/88 (55%), Gaps = 7/88 (7%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL----KALEELNQQLEK--RKE 177
E QE ++Q R E L E +G+E+E R R +L + EEL Q+ E+ R+E
Sbjct: 1039 EKRRLQERERQYR-EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREE 1097
Query: 178 MEEREKRKIIAEEKHKEWVQKKNEQVRR 205
E+R +++ + + +E +Q++ EQ+ R
Sbjct: 1098 PEKRRRQERERQCREEEELQQEEEQLLR 1125
Score = 37.0 bits (84), Expect = 0.014
Identities = 20/82 (24%), Positives = 51/82 (62%), Gaps = 1/82 (1%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE-MEERE 182
E Q+E+++ +L + E +E+EER + +L++ ++L ++ E+R+E + +RE
Sbjct: 494 EERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKRE 553
Query: 183 KRKIIAEEKHKEWVQKKNEQVR 204
+ K + +E+ ++ ++++ E+ R
Sbjct: 554 EEKRLEQERREQRLKREQEERR 575
Score = 36.6 bits (83), Expect = 0.018
Identities = 25/113 (22%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Query: 98 EDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEER 157
E+ + K + +E + +++ E +EE++Q L + +E++ER
Sbjct: 595 EERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQER 654
Query: 158 DRLQLKALEELNQQLEKR--KEMEEREKRKIIAEEKHKEWVQKKNEQVRRGKW 208
+LK EE ++LE+R +E EE + + +AEE+ ++ ++ ++ + +W
Sbjct: 655 REQRLKREEE-EERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQW 706
Score = 36.2 bits (82), Expect = 0.024
Identities = 34/138 (24%), Positives = 63/138 (45%), Gaps = 14/138 (10%)
Query: 79 EDDGDGEDEEDVDDEEDVDEDAHDS----EAKVASLRGMELQGCASTQVESENNQEEQKQ 134
E + ++EE ++ +E D +A+ S RG + E Q ++
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEE 802
Query: 135 VRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE---- 190
+ E R P E +EKE+R R + + +EL Q LE+ ++++ RE+ + + EE
Sbjct: 803 RQQREQRFLPEE-----EEKEQRRRQRREREKEL-QFLEEEEQLQRRERAQQLQEEEDGL 856
Query: 191 KHKEWVQKKNEQVRRGKW 208
+ + ++ EQ R KW
Sbjct: 857 QEDQERRRSQEQRRDQKW 874
Score = 36.2 bits (82), Expect = 0.024
Identities = 27/112 (24%), Positives = 55/112 (49%), Gaps = 1/112 (0%)
Query: 92 DEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIG 151
D + +E+ E + LR + G + E +E+++++R R E F
Sbjct: 1794 DRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853
Query: 152 KEKEERDRLQLKALEELNQQLEK-RKEMEEREKRKIIAEEKHKEWVQKKNEQ 202
+EK R+ +L EE ++ E+ RK EE +R+ E++H++ + K+++
Sbjct: 1854 QEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905
Score = 35.8 bits (81), Expect = 0.031
Identities = 36/159 (22%), Positives = 73/159 (45%), Gaps = 29/159 (18%)
Query: 66 LLSPLGHQSFQFDEDDG-----------DGEDEEDVDDEEDVDEDAHDSEAKVASLRGME 114
L S GH++ +F +++ G +E+ E D + E K R
Sbjct: 193 LQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETV 252
Query: 115 LQGCASTQVESENNQEE----QKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELN- 169
L+ E E QEE Q++++ E +L E + +E++E ++ Q + E
Sbjct: 253 LRK------EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQL 306
Query: 170 ---QQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQVRR 205
Q+ E+R++ EER ++ +E+ ++ +++ +Q+RR
Sbjct: 307 RRKQEEERREQQEERREQ----QERREQQEERREQQLRR 341
Score = 35.4 bits (80), Expect = 0.041
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 9/80 (11%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRK 185
E + EQ+ R E R W +E+ ER E QQL++ +E E RE+
Sbjct: 439 EQERREQRLKREQEERRD----WLKREEETERHEQ-----ERRKQQLKRDQEEERRERWL 489
Query: 186 IIAEEKHKEWVQKKNEQVRR 205
+ EE+ +E +++ +Q+RR
Sbjct: 490 KLEEEERREQQERREQQLRR 509
Score = 34.7 bits (78), Expect = 0.070
Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 30/127 (23%)
Query: 93 EEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGK 152
+ D +E+ + K+ E Q Q+ E QEE+++ RL K
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRRE--QEERREQRL--------------K 520
Query: 153 EKEERDRLQLKALEE--------------LNQQLEKRKEMEEREKRKIIAEEKHKEWVQK 198
+EE +RLQ + E L ++ EKR E E RE+R +E+ ++ + K
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Query: 199 KNEQVRR 205
+ E+ R+
Sbjct: 581 REEERRQ 587
Score = 34.3 bits (77), Expect = 0.091
Identities = 30/146 (20%), Positives = 60/146 (41%), Gaps = 27/146 (18%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
+D +D+ + E + R + Q E E E+Q+++ + +
Sbjct: 111 QDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRD 170
Query: 145 WEVWFIGKEKEER------------------------DRLQLKALEELNQQLEKRKEMEE 180
E+W +E +ER ++L+ + L EL ++ + K+ +
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230
Query: 181 REKR-KIIAEEKHKEWVQKKNEQVRR 205
RE++ ++ EE+ KEW +K E V R
Sbjct: 231 RERQDRVFQEEEEKEW--RKRETVLR 254
Score = 34.3 bits (77), Expect = 0.091
Identities = 29/144 (20%), Positives = 62/144 (43%), Gaps = 12/144 (8%)
Query: 76 QFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQV 135
Q +E E E ++ + E + LR + + Q+ E +E ++Q
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376
Query: 136 RLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
E +L + + +E++ R QL+ ++L ++ + R+E + R ++++ E++ +
Sbjct: 377 LRREQQLRREQQ--LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 196 VQK----------KNEQVRRGKWI 209
QK K EQ R W+
Sbjct: 435 EQKHEQERREQRLKREQEERRDWL 458
Score = 33.5 bits (75), Expect = 0.16
Identities = 31/127 (24%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
Query: 85 EDEEDVDDEEDVDE-DAHDSEA--KVASLRGMELQGCASTQVESENNQEEQKQVRL-PES 140
E EE +EE + H++E LR EL E + Q ++Q R+ E
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 141 RLTPWEV--WFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQK 198
W + KE+E+ + + EL ++ E+ +++E +E R+ EE+ ++ +
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
Query: 199 KNEQVRR 205
+ +Q+RR
Sbjct: 302 REQQLRR 308
Score = 33.5 bits (75), Expect = 0.16
Identities = 25/123 (20%), Positives = 59/123 (47%), Gaps = 13/123 (10%)
Query: 85 EDEEDVDDEE---DVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
E EE+ +++ + +E+ + + + E Q Q+ E ++Q+R +
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ- 412
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
+ +E++ R QL+ +E ++ E++ E E RE+R +E+ ++W++++ E
Sbjct: 413 --------LRREQQLRREQQLRREQE-EERHEQKHEQERREQRLKREQEERRDWLKREEE 463
Query: 202 QVR 204
R
Sbjct: 464 TER 466
Score = 33.1 bits (74), Expect = 0.20
Identities = 22/122 (18%), Positives = 63/122 (51%), Gaps = 10/122 (8%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
+ EE+ ++++ + + + R +L+ + E + +E++++ R + R
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR-- 366
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEK-HKEWVQKKNEQV 203
+++EER QL+ ++L ++ + R+E + R ++++ E++ +E ++ +Q+
Sbjct: 367 -------EQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419
Query: 204 RR 205
RR
Sbjct: 420 RR 421
Score = 33.1 bits (74), Expect = 0.20
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 122 QVESENNQEEQKQVRLPES-RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
Q+ E ++Q+R + R E K ++ER +LK +E + KR+E E
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETE 465
Query: 181 REKRKIIAEEKHKEWVQKKNEQVRRGKWI 209
R + +E+ K+ +++ E+ RR +W+
Sbjct: 466 RHE-----QERRKQQLKRDQEEERRERWL 489
Score = 33.1 bits (74), Expect = 0.20
Identities = 19/77 (24%), Positives = 42/77 (54%), Gaps = 15/77 (19%)
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIA 188
+EE++Q RL ++E+ +RL+ + E ++LE+ + E+R KR+
Sbjct: 582 EEERRQQRL---------------KREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 189 EEKHKEWVQKKNEQVRR 205
EE+ ++ ++ + ++ RR
Sbjct: 627 EERRQQLLKSEEQEERR 643
Score = 33.1 bits (74), Expect = 0.20
Identities = 26/88 (29%), Positives = 45/88 (51%), Gaps = 10/88 (11%)
Query: 124 ESENNQEEQKQVR-LPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEERE 182
E E +EEQ+Q R +SR+ W+ W + + E D Q K +Q +R+ E+ E
Sbjct: 682 EQELAEEEQEQARERIKSRIPKWQ-WQL---ESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 183 KRK-----IIAEEKHKEWVQKKNEQVRR 205
KR+ + +E+ + Q++ E+ RR
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRR 765
Score = 33.1 bits (74), Expect = 0.20
Identities = 32/142 (22%), Positives = 68/142 (47%), Gaps = 16/142 (11%)
Query: 78 DEDDGDGEDEEDVDDEED---------VDEDA----HDSEAKVASLRGMELQGCASTQVE 124
+E+DG ED+E +E ++E+ H AK A + + + E
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 125 SENNQEEQKQVRLPESRLTPWEVWFIGKEKEE--RDRLQLKALEELNQQLEKRKEMEERE 182
E +EE+++ R E E + +E+E+ R+ + + +E +Q K K+++++E
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 183 KRKIIAEEKHKEWVQKKNEQVR 204
+ +++ EE K Q++ ++ R
Sbjct: 971 E-QLLGEEPEKRRRQEREKKYR 991
Score = 31.6 bits (70), Expect = 0.59
Identities = 22/79 (27%), Positives = 42/79 (53%), Gaps = 3/79 (3%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
E E Q+E++Q+ E + W ++ ++D LQ + + L ++ EKR+ ++ERE+
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEW--ERQYRKKDELQQEEEQLLREEREKRR-LQERER 1048
Query: 184 RKIIAEEKHKEWVQKKNEQ 202
+ EE +E Q E+
Sbjct: 1049 QYREEEELQQEEEQLLGEE 1067
Score = 31.6 bits (70), Expect = 0.59
Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 12/125 (9%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E+EE +EE + + + R EL+ + E E QEE++ +R +
Sbjct: 1112 EEEELQQEEEQLLREEREKR------RRQELE--RQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 145 WEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQVR 204
E + ++ E + LQ + + L ++ EKR++ ER+ R+ ++ K + ++E R
Sbjct: 1164 QE---LERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQR 1220
Query: 205 RG-KW 208
KW
Sbjct: 1221 SDLKW 1225
Score = 31.6 bits (70), Expect = 0.59
Identities = 26/126 (20%), Positives = 64/126 (50%), Gaps = 9/126 (7%)
Query: 86 DEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPW 145
D + +++E+ + D + + LR E + + + + Q+ Q++ E +L
Sbjct: 1484 DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ 1543
Query: 146 EVWFIGKEKEERDRLQLKALEELNQQLEKRK-EMEEREKRKIIAEEKHKEWVQKK----- 199
E + +++RDR + + E+L Q+ E+++ +ER+++ + E+K + Q++
Sbjct: 1544 ERG--QQRRQDRDR-KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED 1600
Query: 200 NEQVRR 205
+Q+RR
Sbjct: 1601 EQQLRR 1606
Score = 31.2 bits (69), Expect = 0.77
Identities = 18/54 (33%), Positives = 31/54 (57%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQVRR 205
+E+EER LK EE QQ KR++ E E+R E + E +++ ++++R
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKR 622
Score = 30.8 bits (68), Expect = 1.0
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
Query: 130 EEQKQVRLPESRLTPWEVWFIGKEKE------ERDRLQLKALEELNQQLEKRKEMEEREK 183
EE++Q+R R E + + +E ERDR L+ ++L +Q E+ ++ E+E
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ-ERDRKFREQEL 1508
Query: 184 RKIIAEEKHKEWVQKKNEQVRRGKWI 209
R E K E Q+ + Q R+ K++
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFL 1534
Score = 30.4 bits (67), Expect = 1.3
Identities = 25/88 (28%), Positives = 48/88 (54%), Gaps = 7/88 (7%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQL--KALEELNQQLEKRKEM--- 178
E + +EEQK+ + + R + E + +E+EE+ R Q + E Q L++R+E
Sbjct: 1296 EEQLEREEQKEAKRRD-RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 179 -EEREKRKIIAEEKHKEWVQKKNEQVRR 205
+ER+++ E +H+E +K E+ +R
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQR 1382
Score = 30.0 bits (66), Expect = 1.7
Identities = 33/130 (25%), Positives = 60/130 (46%), Gaps = 21/130 (16%)
Query: 85 EDEEDVDDEEDVDEDAH--DSEAKVASLRGMELQGCASTQVESENN----QEEQKQVRLP 138
E+EE + +E ++ E + L+ E + ++ SE QEE+++ L
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 139 ---ESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEW 195
E RL E+E R++ + EE QL KR+ EER ++++ E++ +
Sbjct: 552 REEEKRL----------EQERREQRLKREQEERRDQLLKRE--EERRQQRLKREQEERLE 599
Query: 196 VQKKNEQVRR 205
+ K E+V R
Sbjct: 600 QRLKREEVER 609
Score = 30.0 bits (66), Expect = 1.7
Identities = 26/118 (22%), Positives = 58/118 (49%), Gaps = 6/118 (5%)
Query: 92 DEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIG 151
D + +E+ E + LR E + + QE +++ E +L E+
Sbjct: 1666 DRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKF 1725
Query: 152 KEKE----ERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQVRR 205
+E+E E ++ QL+ E + LE+ + ERE++++ +E+ +++ ++ EQ+R+
Sbjct: 1726 REEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKF--REEEQLRQ 1781
Score = 29.3 bits (64), Expect = 2.9
Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 9/86 (10%)
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKE----KEERDRLQLKALEELN-----QQLEKRKEME 179
QE ++ R E R F+ +E ++ER+R LK ++L QQL + ++ +
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 180 EREKRKIIAEEKHKEWVQKKNEQVRR 205
RE+ + ++ ++ +++ +QVRR
Sbjct: 1416 FREEEQQLSRQERDRKFREEEQQVRR 1441
Score = 29.3 bits (64), Expect = 2.9
Identities = 21/91 (23%), Positives = 50/91 (54%), Gaps = 23/91 (25%)
Query: 120 STQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQ-----LEK 174
S Q +EE++QVR ++ER+R L+ ++L Q+ E+
Sbjct: 1424 SRQERDRKFREEEQQVR-----------------RQERERKFLEEEQQLRQERHRKFREE 1466
Query: 175 RKEMEEREKRKIIAEEKHKEWVQKKNEQVRR 205
+ ++ERE++++ +E+ +++++++ +Q+RR
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEE-QQLRR 1496
Score = 28.9 bits (63), Expect = 3.8
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 5/84 (5%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
+ E ++E++++ R P E +E++E R K+ EE E+R+E R++
Sbjct: 1274 QQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE 1333
Query: 184 --RKIIAEEKHKEWVQKKNEQVRR 205
RK EE + +Q++ EQ R
Sbjct: 1334 TDRKFREEE---QLLQEREEQPLR 1354
Score = 28.9 bits (63), Expect = 3.8
Identities = 23/96 (23%), Positives = 51/96 (53%), Gaps = 6/96 (6%)
Query: 114 ELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKE----ERDRLQLKALEELN 169
E Q ++E + +EEQ + + +L E + E+E ER+ QL+ E
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 170 QQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQVRR 205
+ E+ + +ERE++++ ++E +++ ++ EQ+R+
Sbjct: 1772 KFREEEQLRQEREEQQLRSQESDRKF--REEEQLRQ 1805
Score = 28.9 bits (63), Expect = 3.8
Identities = 19/79 (24%), Positives = 39/79 (49%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
E + EQ+Q+R E E + E+EE+ + + + ++ + R+E EE++
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL 1788
Query: 184 RKIIAEEKHKEWVQKKNEQ 202
R ++ K +E Q + E+
Sbjct: 1789 RSQESDRKFREEEQLRQER 1807
Score = 27.7 bits (60), Expect = 8.5
Identities = 20/80 (25%), Positives = 44/80 (55%), Gaps = 11/80 (13%)
Query: 129 QEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIA 188
QE ++Q+R R E + ++ ERDR + +++ +Q +RK +EE ++ +
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQ--ERDRKFREEEQQVRRQERERKFLEEEQQ---LR 1456
Query: 189 EEKHKEW------VQKKNEQ 202
+E+H+++ +Q++ EQ
Sbjct: 1457 QERHRKFREEEQLLQEREEQ 1476
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 40.8 bits (94), Expect = 0.001
Identities = 19/54 (35%), Positives = 29/54 (53%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEE 131
DEDD D ED+ED DDE+D +E+ + E V G + A + E +++
Sbjct: 244 DEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297
Score = 40.4 bits (93), Expect = 0.001
Identities = 31/119 (26%), Positives = 57/119 (47%), Gaps = 8/119 (6%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEA------KVASLRGMELQGCASTQVESENNQEE 131
DEDD D ED+ED DD+E+ D + E K A + ++ + A + E E++++E
Sbjct: 186 DEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDE 245
Query: 132 QKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
E + +E+EE + +A + +++ K+K E +K+K+ E
Sbjct: 246 DDDD--DEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302
Score = 39.3 bits (90), Expect = 0.003
Identities = 23/86 (26%), Positives = 40/86 (46%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+EDD D +D++D DDE+D DED + E + E G ++ + E K+ ++
Sbjct: 239 EEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKV 298
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLK 163
+ T F+G + +LK
Sbjct: 299 EGTEPTTAFNLFVGNLNFNKSAPELK 324
Score = 32.3 bits (72), Expect = 0.35
Identities = 13/55 (23%), Positives = 33/55 (60%), Gaps = 4/55 (7%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQ 132
++ D + +D+ + D+E+D DED + E + A+++ A+ E E++++++
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKA----AAAAPASEDEDDEDDE 193
Score = 31.6 bits (70), Expect = 0.59
Identities = 33/188 (17%), Positives = 76/188 (40%), Gaps = 8/188 (4%)
Query: 17 GFSADCRPRSRPSSDSCSVPMTGARGQ--GLEVVRSPSPPLPLSCSNSTRSLLSPLGHQS 74
G A P + + + +V G +G G +V +P + ++ + S
Sbjct: 86 GKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDS 145
Query: 75 FQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQ 134
+ ++DD + ++E+D D++ED DE + A+ E + + + +++ +E+
Sbjct: 146 DEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDD 205
Query: 135 VRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKE 194
TP K K+ + +KA + E+ + +E + E+ E
Sbjct: 206 SEEEAMETTP------AKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDDE 259
Query: 195 WVQKKNEQ 202
+++ E+
Sbjct: 260 DDEEEEEE 267
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/141 (21%), Positives = 67/141 (47%), Gaps = 19/141 (13%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
+ EE + +EE + E + ++R E + + E ++E +Q RLPE +
Sbjct: 441 DQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 500
Query: 145 WE----------VWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER--EKRKIIAEEKH 192
WE +W +E++ RD+ ++ E+ + EK +E E++ E+ + + +++
Sbjct: 501 WEQEKMQEQEEKIW--EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 558
Query: 193 KEW-----VQKKNEQVRRGKW 208
K W ++KK ++ + W
Sbjct: 559 KMWDQEERMEKKTQEQEKKTW 579
Score = 39.7 bits (91), Expect = 0.002
Identities = 32/133 (24%), Positives = 67/133 (50%), Gaps = 14/133 (10%)
Query: 85 EDEEDVDDEED----VDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E E+ + D+E+ DE + E ++ M Q E + QE++K+ R E
Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ--VEKMREEKKMQEQEKKTRDQEE 444
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE----MEERE-KRKIIAEEKHKEW 195
++ E +E+E++ R + + + E ++++K++E EE+E +++ + E+K K W
Sbjct: 445 KMQEEERI---REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW 501
Query: 196 VQKKNEQVRRGKW 208
Q+K ++ W
Sbjct: 502 EQEKMQEQEEKIW 514
Score = 39.3 bits (90), Expect = 0.003
Identities = 37/126 (29%), Positives = 68/126 (53%), Gaps = 16/126 (12%)
Query: 85 EDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E EE + ++E+ +E + E K M Q + E + ++EQK +R E
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEK------MWRQEERLWEQEKQMREQEQK-MRDQEE 397
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEK--HKEWVQK 198
R+ WE +EKEER R Q K E++ +++ + K+M+E+EK+ EEK +E +++
Sbjct: 398 RM--WEQDERLREKEERMREQEKMWEQV-EKMREEKKMQEQEKKTRDQEEKMQEEERIRE 454
Query: 199 KNEQVR 204
+ +++R
Sbjct: 455 REKKMR 460
Score = 39.3 bits (90), Expect = 0.003
Identities = 31/139 (22%), Positives = 65/139 (46%), Gaps = 15/139 (10%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+++D E EE + D+E D + K + + E E +E +K++R
Sbjct: 541 EQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQL-EKRKEMEEREKRKIIAEEK----- 191
E + +E+EE+ + Q + ++E +++ E+ ++M+E+E++ EEK
Sbjct: 601 EEEMM---------REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 651
Query: 192 HKEWVQKKNEQVRRGKWIH 210
K W Q++ + + W H
Sbjct: 652 EKMWEQQRLPEQKEKLWEH 670
Score = 39.3 bits (90), Expect = 0.003
Identities = 33/132 (25%), Positives = 65/132 (49%), Gaps = 17/132 (12%)
Query: 72 HQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEE 131
H+ Q E + E EE + ++E +++ + E K M E E+ +E
Sbjct: 670 HEKMQ--EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMR---------EEESMRER 718
Query: 132 QKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEERE-KRKIIAEE 190
+K++R E + E K +E+ +++Q + EE+ +Q EK E EE+ +++ + E+
Sbjct: 719 EKKMREEEEMMREQEE----KMQEQEEKMQEQE-EEMWEQEEKMWEQEEKMWEQQRLPEQ 773
Query: 191 KHKEWVQKKNEQ 202
K K W +K ++
Sbjct: 774 KEKLWEHEKMQE 785
Score = 36.2 bits (82), Expect = 0.024
Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 12/91 (13%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKE------------KEERDRLQLKALEELNQQ 171
+ E +E++K++R E ++ E +E +E+R R Q K L E ++
Sbjct: 277 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKE 336
Query: 172 LEKRKEMEEREKRKIIAEEKHKEWVQKKNEQ 202
L ++KE+ E+E++ EEK E +K EQ
Sbjct: 337 LREQKELREQEEQMQEQEEKMWEQEEKMREQ 367
Score = 35.8 bits (81), Expect = 0.031
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
Query: 85 EDEEDVDDEEDVDEDAH---DSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
E +E + ++E + E + E K+ M Q + E QE+Q + + R
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
++W + E++ + Q K + +++ + + M EREK+ EE +E +K E
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 202 Q 202
Q
Sbjct: 615 Q 615
Score = 35.8 bits (81), Expect = 0.031
Identities = 32/142 (22%), Positives = 61/142 (42%), Gaps = 14/142 (9%)
Query: 70 LGHQSFQFDEDDGDGEDEEDVDDEEDV---------DEDAHDSEAKVASLRGMELQGCAS 120
L Q ++++ E EE + D+E++ E + E ++ E +
Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM-----WEQEEKMR 554
Query: 121 TQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEE 180
Q + +QEE+ + + E W+ +E+E + K EE E+ ++M+E
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 181 REKRKIIAEEKHKEWVQKKNEQ 202
+E++ EEK E +K EQ
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQ 636
Score = 35.0 bits (79), Expect = 0.053
Identities = 24/82 (29%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
+ E +E++ ++R E ++ E +EKE R+ Q K L E + E+ ++M+E+E+
Sbjct: 298 QEERLREQEGKMREQEEKMWRQEKRLREQEKELRE--QEKELREQKELREQEEQMQEQEE 355
Query: 184 RKIIAEEKHKEWVQKKNEQVRR 205
+ EEK +E +K Q R
Sbjct: 356 KMWEQEEKMREQEEKMWRQEER 377
Score = 34.7 bits (78), Expect = 0.070
Identities = 28/124 (22%), Positives = 62/124 (50%), Gaps = 9/124 (7%)
Query: 85 EDEEDVDDEEDVDEDAH--DSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRL 142
++++ D EE + E+ + E K+ M + Q + E QE+++++ E ++
Sbjct: 574 QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKM 633
Query: 143 TPWEVWFIGKEK----EERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQK 198
E +E+ +E + + L E ++L + ++M+E+EK + E++ K W Q+
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEK---MQEQEEKIWEQE 690
Query: 199 KNEQ 202
K E+
Sbjct: 691 KMEK 694
Score = 34.7 bits (78), Expect = 0.070
Identities = 32/132 (24%), Positives = 64/132 (48%), Gaps = 13/132 (9%)
Query: 78 DEDDGDGEDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQK 133
++++ E EE + ++E+ +E + E K+ E Q + + +++ Q+
Sbjct: 621 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM-----WEQQRLPEQKEKLWEHEKMQE 675
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRL---QLKALEELNQQLEKRKEMEEREKRKIIAEE 190
Q ++ E WE + K+ +E+++ Q K EE + + E+ K+M E E+ EE
Sbjct: 676 QEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR-EREKKMREEEEMMREQEE 734
Query: 191 KHKEWVQKKNEQ 202
K +E +K EQ
Sbjct: 735 KMQEQEEKMQEQ 746
Score = 33.5 bits (75), Expect = 0.16
Identities = 31/131 (23%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Query: 73 QSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQ 132
+ Q E+ ++E+ + EE + E E K ++Q Q + E E++
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690
Query: 133 K-QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEK 191
K + + E W+ + +E+ R+R + K EE E+ ++M+E+E++ EE+
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMRER-EKKMREEEEMMREQEEKMQEQEEKMQEQEEE 749
Query: 192 HKEWVQKKNEQ 202
E +K EQ
Sbjct: 750 MWEQEEKMWEQ 760
Score = 33.1 bits (74), Expect = 0.20
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 13/94 (13%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQ--------QLEKR 175
E + ++E+K R E RL E +EKE R++ +L+ EE Q Q EK
Sbjct: 306 EGKMREQEEKMWR-QEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKM 364
Query: 176 KEMEE---REKRKIIAEEKH-KEWVQKKNEQVRR 205
+E EE R++ ++ +EK +E QK +Q R
Sbjct: 365 REQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 398
Score = 32.0 bits (71), Expect = 0.45
Identities = 24/85 (28%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 124 ESENNQEEQKQVR-----LPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQL-EKRKE 177
E E EQK++R + E WE +E+EE+ Q + L E +Q+ E+ ++
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK 391
Query: 178 MEEREKRKIIAEEKHKEWVQKKNEQ 202
M ++E+R +E+ +E ++ EQ
Sbjct: 392 MRDQEERMWEQDERLREKEERMREQ 416
Score = 30.8 bits (68), Expect = 1.0
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 6/86 (6%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKE---KEERDRLQLKALEELNQQLEK-RKEMEER 181
+ N E Q+++ L ES + E+ KE K ER + L ++ Q E R+E E R
Sbjct: 225 KKNAELQEKLPLAESEKS--EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 282
Query: 182 EKRKIIAEEKHKEWVQKKNEQVRRGK 207
E+ K I +++ K W Q++ + + GK
Sbjct: 283 EQEKKIRKQEEKMWRQEERLREQEGK 308
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 10/136 (7%)
Query: 78 DEDDGDGEDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQK 133
+E++ E EE + ++E+ +E + E K+ + ++ E E EQ+
Sbjct: 16 EEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQE-QEEKMWEQEEKMWEQEEKMWEQQ 74
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER--EKRKIIAEEK 191
RLPE + WE +EKEER R Q K +++ + EK+K EE+ E+ + + E++
Sbjct: 75 --RLPEQKEKMWEQDERLREKEERMREQ-KMWQQVEKMREKKKTQEEKMQEQEEKMQEQE 131
Query: 192 HKEWVQKKNEQVRRGK 207
W Q++ Q + K
Sbjct: 132 EMMWEQEEKMQEQEEK 147
Score = 37.4 bits (85), Expect = 0.011
Identities = 28/137 (20%), Positives = 68/137 (49%), Gaps = 20/137 (14%)
Query: 78 DEDDGDGEDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQK 133
++++ E EE + ++E+ +E + E K+ + + Q E E+ +
Sbjct: 37 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ--------KEKMWEQDE 88
Query: 134 QVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE--------MEEREKRK 185
++R E R+ ++W ++ E+ + Q + ++E +++++++E M+E+E++
Sbjct: 89 RLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWEQEEKMQEQEEKM 148
Query: 186 IIAEEKHKEWVQKKNEQ 202
EEK +E +K EQ
Sbjct: 149 WEQEEKMREQEEKMREQ 165
Score = 32.7 bits (73), Expect = 0.26
Identities = 22/86 (25%), Positives = 49/86 (56%), Gaps = 5/86 (5%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE-MEERE 182
E E +E +K++R E + E +E+EE+ R Q + + E +++++++E M E+E
Sbjct: 3 EEERMREREKKMREEEEMMREQEEKM--QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 60
Query: 183 KRKIIAEEKHKEWVQKKNEQVRRGKW 208
++ + E++ K W Q++ + + W
Sbjct: 61 EK--MWEQEEKMWEQQRLPEQKEKMW 84
Score = 28.9 bits (63), Expect = 3.8
Identities = 16/51 (31%), Positives = 27/51 (52%)
Query: 152 KEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQ 202
+E+E + K EE E+ ++M+E+E++ EEK E +K EQ
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQ 52
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
[Homo sapiens]
Length = 3969
Score = 40.4 bits (93), Expect = 0.001
Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 125 SENNQEEQKQVRLP-----ESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEME 179
+E NQ +KQ P S TP WF + ER R + KA EEL++ + K +E
Sbjct: 810 AEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVE 869
Query: 180 EREKRKIIAEEKHKEWVQKKNEQVRRGKWIHTLTSL 215
+ + R+ E + + + + E+ ++G I + ++L
Sbjct: 870 KDKSRERDREREKENKRESRKEKRKKGSEIQSSSAL 905
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 40.4 bits (93), Expect = 0.001
Identities = 36/124 (29%), Positives = 63/124 (50%), Gaps = 12/124 (9%)
Query: 86 DEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPW 145
+E++ + EE E+ + E K+ + + + V +E++ E + PE T
Sbjct: 11 EEKEDETEESSSEEEEEVEDKLPRRESLRPKRKRTRDVINEDDPEPE-----PEDEETRK 65
Query: 146 EVWFIGKEKEERDRLQLKALEE-LNQQLEKRKEMEEREKRKIIAEEKHKEW-VQKKNEQV 203
+EKE R RL+ A EE ++++ +R + E EKR+IIA K K W ++KK E +
Sbjct: 66 -----AREKERRRRLKRGAEEEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVL 120
Query: 204 RRGK 207
+ K
Sbjct: 121 KEAK 124
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 40.4 bits (93), Expect = 0.001
Identities = 30/124 (24%), Positives = 57/124 (45%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+E+ G+GE+EE +EE+ E E + + G + + E +EE+ +
Sbjct: 732 EEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEG 791
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ 197
+ E G+EKEE ++ +EE + E+ +E E E+ + EE+ E +
Sbjct: 792 DQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEE 851
Query: 198 KKNE 201
++ E
Sbjct: 852 EEGE 855
Score = 36.2 bits (82), Expect = 0.024
Identities = 30/132 (22%), Positives = 62/132 (46%), Gaps = 18/132 (13%)
Query: 71 GHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQE 130
G + + + ++G+GE EE+ + E +E+ + E +G + E E +E
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG---------EEEGEGEEEGEGEGEEE 1016
Query: 131 EQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE 190
E+ +V E + E G+E+E + + + E ++ + +E EE E E
Sbjct: 1017 EEGEV---EGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE------EG 1067
Query: 191 KHKEWVQKKNEQ 202
K++E +++NE+
Sbjct: 1068 KYQETGEEENER 1079
Score = 35.4 bits (80), Expect = 0.041
Identities = 30/124 (24%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+E +G+GE+EE ++ E+ E + E + E++G + E E EE++
Sbjct: 984 EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGE-EGEGEGEEEEGEEE 1042
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKI---IAEEKHKE 194
E R E + +EE + + K E ++ E++ E ++ KI + KHK
Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKT 1102
Query: 195 WVQK 198
+ +K
Sbjct: 1103 YQKK 1106
Score = 33.5 bits (75), Expect = 0.16
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 7/135 (5%)
Query: 80 DDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPE 139
+DG+GE EE+ + E +E+ + G E +G + +EE+ + E
Sbjct: 942 EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Query: 140 SRLTPWEVWFIGKEKEERD---RLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWV 196
E G+E+EE + ++ + E ++ E +E EEREK E +
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRR---- 1057
Query: 197 QKKNEQVRRGKWIHT 211
++ E+ GK+ T
Sbjct: 1058 NREEEEEEEGKYQET 1072
Score = 32.0 bits (71), Expect = 0.45
Identities = 27/128 (21%), Positives = 55/128 (42%), Gaps = 6/128 (4%)
Query: 79 EDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLP 138
E++G+GE EE+ + E + + + + E + G E + E E N+ +++
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEE 1065
Query: 139 ESRLTPWEVWFIGKEKEER-DRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ 197
E + G+E+ ER D + K + ++ ++ K ++K + KE
Sbjct: 1066 EGKYQE-----TGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGKEQRS 1120
Query: 198 KKNEQVRR 205
K Q +R
Sbjct: 1121 KMPVQSKR 1128
Score = 29.6 bits (65), Expect = 2.2
Identities = 31/134 (23%), Positives = 59/134 (44%), Gaps = 10/134 (7%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+E++G+GE+EE +EE+ + + + E K G E +G + +EE+ +
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEGK-GEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ 197
E E G+E+E + + E ++ + K EE E+ + EE+ E
Sbjct: 888 EE------EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941
Query: 198 KKNE---QVRRGKW 208
+ E + G+W
Sbjct: 942 EDGEGEGEEEEGEW 955
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 40.0 bits (92), Expect = 0.002
Identities = 30/127 (23%), Positives = 62/127 (48%), Gaps = 14/127 (11%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTP 144
E EE + +EE + E + ++R E + + E ++E +Q RLPE +
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL 442
Query: 145 WE----------VWFIGKEKEERDRLQLKALEELNQQLEKRKEMEER--EKRKIIAEEKH 192
WE +W +E++ RD+ ++ E+ + EK +E E++ E+ + + +++
Sbjct: 443 WEQEKMQEQEEKIW--EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Query: 193 KEWVQKK 199
K W Q++
Sbjct: 501 KMWDQEE 507
Score = 38.9 bits (89), Expect = 0.004
Identities = 32/121 (26%), Positives = 57/121 (47%), Gaps = 9/121 (7%)
Query: 85 EDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEE---QKQVRLPESR 141
+ EE + +EE + E + +R E + Q E QEE +++ ++ E
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEK--MQEQEEKMREQEEKMWEQEEKMQEQE 608
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNE 201
WE E+EE D++Q E+ E+ ++M+E+E++ EEK +E +K E
Sbjct: 609 EKMWEQEEKMWEQEEEDKMQ----EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE 664
Query: 202 Q 202
Q
Sbjct: 665 Q 665
Score = 36.6 bits (83), Expect = 0.018
Identities = 28/128 (21%), Positives = 61/128 (47%), Gaps = 24/128 (18%)
Query: 85 EDEEDVDDEED----VDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E E+ + D+E+ DE + E ++ M E E +E++++R E
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERMREQEKMW---------EQEEKMQEEERIREREK 399
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKN 200
++ +E+EE R Q + +++ + + +++E E +++R + E+K K W Q+K
Sbjct: 400 KM---------REEEETMREQEEKMQKQEENMWEQEEKEWQQQR--LPEQKEKLWEQEKM 448
Query: 201 EQVRRGKW 208
++ W
Sbjct: 449 QEQEEKIW 456
Score = 36.6 bits (83), Expect = 0.018
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 8/125 (6%)
Query: 70 LGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQ 129
L Q ++++ E EE + D+E++ E K+ M Q + E +
Sbjct: 442 LWEQEKMQEQEEKIWEQEEKIRDQEEM----WGQEKKMWRQEKMREQEDQMWEQEEKMRD 497
Query: 130 EEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAE 189
+EQK E WE +EKEER R Q K ++ +++ + K+ +E+EK+ E
Sbjct: 498 QEQKMWDQEERM---WEQDERLREKEERMREQKKMWQQ-EEKMREEKKTQEQEKKTWDQE 553
Query: 190 EKHKE 194
EK +E
Sbjct: 554 EKMRE 558
Score = 35.4 bits (80), Expect = 0.041
Identities = 26/94 (27%), Positives = 50/94 (53%), Gaps = 10/94 (10%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIG-----KEKEERDRLQLKALEELNQQL-EKRKE 177
+ E +E++K++R E ++ E +E+EE+ R Q K L E ++L E+ KE
Sbjct: 239 QEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKE 298
Query: 178 MEE----REKRKIIAEEKHKEWVQKKNEQVRRGK 207
+ E RE+ + + E++ K W Q++ + + K
Sbjct: 299 LREQKKLREQEEQMQEQEEKMWEQEEKMREQEEK 332
Score = 35.4 bits (80), Expect = 0.041
Identities = 31/121 (25%), Positives = 57/121 (47%), Gaps = 12/121 (9%)
Query: 97 DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEE 156
+E+ + E K+ + + + +E+++++R E RL E +EKE
Sbjct: 240 EEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKEL 299
Query: 157 RDRLQLKALEELNQ--------QLEKRKEMEE---REKRKIIAEEKH-KEWVQKKNEQVR 204
R++ +L+ EE Q Q EK +E EE R++ ++ +EK +E QK +Q
Sbjct: 300 REQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 359
Query: 205 R 205
R
Sbjct: 360 R 360
Score = 35.4 bits (80), Expect = 0.041
Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 22/136 (16%)
Query: 78 DEDDGDGEDEEDVDDEE-----------DVDEDAHDSEAKVASLRGMELQGCASTQVESE 126
+++D E EE + D+E + DE + E ++ + M Q E +
Sbjct: 483 EQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ--EEKMREEK 540
Query: 127 NNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKI 186
QE++K+ E ++ +E+E + K EE E+ ++M+E+E++
Sbjct: 541 KTQEQEKKTWDQEEKM---------REEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Query: 187 IAEEKHKEWVQKKNEQ 202
EEK E +K EQ
Sbjct: 592 EQEEKMWEQEEKMQEQ 607
Score = 33.5 bits (75), Expect = 0.16
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 6/86 (6%)
Query: 126 ENNQEEQKQVRLPESRLTPWEVWFIGKE---KEERDRLQLKALEELNQQLEK-RKEMEER 181
+ N E Q+++RL ES + E+ KE K ER + L ++ Q E R+E E R
Sbjct: 187 KKNAELQEKLRLAESEKS--EIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELR 244
Query: 182 EKRKIIAEEKHKEWVQKKNEQVRRGK 207
E+ K I +++ K W Q++ + + GK
Sbjct: 245 EQEKKIRKQEEKMWRQEERLREQEGK 270
Score = 33.5 bits (75), Expect = 0.16
Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 21/128 (16%)
Query: 85 EDEEDVDDEEDV----DEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPES 140
E EE + ++E+ +E + E K M Q + E + ++EQK +R E
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEK------MWRQEERLWEQEKQMREQEQK-MRDQEE 359
Query: 141 RLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEE-----KHKEW 195
R+ WE +EKEER R Q K E+ +++++ + + EREK+ + EE + +E
Sbjct: 360 RM--WEQDERLREKEERMREQEKMWEQ-EEKMQEEERIREREKK--MREEEETMREQEEK 414
Query: 196 VQKKNEQV 203
+QK+ E +
Sbjct: 415 MQKQEENM 422
Score = 33.1 bits (74), Expect = 0.20
Identities = 29/125 (23%), Positives = 59/125 (47%), Gaps = 11/125 (8%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+E ++++ D EE + E+ E + E+ + + E QE+++++R
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM-----REQEEKMQEQEEKMRE 592
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ 197
E ++ WE +EK + ++ EE + E+ +M+E+E+ EEK +E +
Sbjct: 593 QEEKM--WEQ----EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 198 KKNEQ 202
K EQ
Sbjct: 647 KMWEQ 651
Score = 32.7 bits (73), Expect = 0.26
Identities = 26/87 (29%), Positives = 48/87 (55%), Gaps = 10/87 (11%)
Query: 124 ESENNQEEQKQVRLPESRLTPWE--VWFIGKEKEERDRLQLKALEELNQQL-EKRKEMEE 180
E E EQK++R E ++ E +W E+EE+ R Q + + ++L E+ K+M E
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMW----EQEEKMREQEEKMWRQEERLWEQEKQMRE 349
Query: 181 REKRKIIAEEK---HKEWVQKKNEQVR 204
+E++ EE+ E +++K E++R
Sbjct: 350 QEQKMRDQEERMWEQDERLREKEERMR 376
Score = 32.3 bits (72), Expect = 0.35
Identities = 26/125 (20%), Positives = 56/125 (44%), Gaps = 9/125 (7%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
+E++ E EE + ++E E + E K+ + + E E++++ ++
Sbjct: 571 EEEEMMREQEEKMQEQE---EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM 627
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ 197
E WE ++E+ + K E+ + E+ ++M E+E++ EEK +E +
Sbjct: 628 QEQEEMMWE------QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 198 KKNEQ 202
K Q
Sbjct: 682 KMQGQ 686
Score = 31.2 bits (69), Expect = 0.77
Identities = 28/122 (22%), Positives = 58/122 (47%), Gaps = 11/122 (9%)
Query: 85 EDEEDVDDEEDVDEDAH---DSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESR 141
E +E + ++E + E + E K+ M Q + E QE+Q + + R
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 496
Query: 142 LTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKR----KIIAEEKHKEWVQ 197
++W ++EER Q + L E +++ ++K+M ++E++ K E++ K W Q
Sbjct: 497 DQEQKMW----DQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQ 552
Query: 198 KK 199
++
Sbjct: 553 EE 554
Score = 30.4 bits (67), Expect = 1.3
Identities = 22/92 (23%), Positives = 47/92 (51%), Gaps = 10/92 (10%)
Query: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKE------ 177
E E +E +K++R E + E +E+EE+ R Q + + E +++++++E
Sbjct: 558 EEERMREREKKMREEEEMMREQEEKM--QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 178 --MEEREKRKIIAEEKHKEWVQKKNEQVRRGK 207
M E+E+ + E++ W Q++ Q + K
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 40.0 bits (92), Expect = 0.002
Identities = 32/127 (25%), Positives = 63/127 (49%), Gaps = 9/127 (7%)
Query: 85 EDEEDVDDEED--VDEDAHDSEAK-----VASLRGMELQGCASTQVESENNQEEQKQVRL 137
E +E + +E+D +D+ E K VA ++ +L+ + QE++ +V
Sbjct: 1486 EQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSE 1545
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRK-IIAEEKHKEWV 196
+ + + W +G +K+E ++ALEE +Q E+ ++E + RK + EEK E V
Sbjct: 1546 KKDQALEQKYWALG-QKDEALEQNIQALEENHQTQEQESLVQEDKTRKPKMLEEKSPEKV 1604
Query: 197 QKKNEQV 203
+ E++
Sbjct: 1605 KAMEEKL 1611
Score = 30.8 bits (68), Expect = 1.0
Identities = 31/113 (27%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
Query: 91 DDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFI 150
D+ V +A + K +G +L+ T +E ++ E K L E + I
Sbjct: 1391 DEALHVKNEAVKQQDKALEQKGRDLEQ-KDTALEQKDKALEPKDKDLEEKDKALEQKDKI 1449
Query: 151 GKEKEERDRLQLKALEELNQQLE-KRKEMEER----EKRKIIAEEKHKEWVQK 198
+EK++ + ALE+ ++ LE K K++E++ E+++ I EEK K QK
Sbjct: 1450 PEEKDKALEQKDTALEQKDKALEPKDKDLEQKDRVLEQKEKIPEEKDKALDQK 1502
Score = 30.0 bits (66), Expect = 1.7
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 10/97 (10%)
Query: 9 PTFP-SSYAGFSADCRPRSRPSSD-SCSVPMTGARGQGLEVVRSPSPPLP---LSCSNST 63
PTF ++ AG + RP PS + S + P R L + PSPPL LSCS
Sbjct: 2031 PTFSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILS--KGPSPPLNGNILSCSPDR 2088
Query: 64 RSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDA 100
R SP +S + DD + E + E +++A
Sbjct: 2089 R---SPSPKESGRSHWDDSTSDSELEKGAREQPEKEA 2122
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 40.0 bits (92), Expect = 0.002
Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 20/130 (15%)
Query: 78 DEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRL 137
D D G+ E EE+ DDEE+++E K+A +G S N E QK +
Sbjct: 574 DNDTGNEEQEEEEDDEEEMEE-------KLAKAKG-------SQAPSLPNTSEAQKIKEV 619
Query: 138 PESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQ 197
P L E E+E+ D L++K L+ K ++++E K ++K + +
Sbjct: 620 PTQFLDRDE------EEEDADFLKVKRHNVFGLDLKDEKTLQKKEPSKSSIKKKMTKVAE 673
Query: 198 KKNEQVRRGK 207
K R K
Sbjct: 674 AKKVMKRNFK 683
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,140,207
Number of Sequences: 37866
Number of extensions: 552518
Number of successful extensions: 12252
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 393
Number of HSP's successfully gapped in prelim test: 580
Number of HSP's that attempted gapping in prelim test: 5524
Number of HSP's gapped (non-prelim): 4029
length of query: 229
length of database: 18,247,518
effective HSP length: 99
effective length of query: 130
effective length of database: 14,498,784
effective search space: 1884841920
effective search space used: 1884841920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.