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Search of human proteins with 17978475
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17978475 oligodendrocyte lineage transcription factor 2
[Homo sapiens]
(323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 647 0.0
gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens] 272 3e-73
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 138 8e-33
gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens] 109 3e-24
gi|57529222 basic helix-loop-helix domain containing, class B, 4... 105 4e-23
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 73 3e-13
gi|31077092 neurogenin 2 [Homo sapiens] 67 3e-11
gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 66 4e-11
gi|121114306 neurogenic differentiation 1 [Homo sapiens] 65 1e-10
gi|153792190 neurogenic differentiation 4 [Homo sapiens] 65 1e-10
gi|38455396 neurogenin 1 [Homo sapiens] 64 2e-10
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 59 6e-09
gi|27475985 neurogenic differentiation 6 [Homo sapiens] 57 2e-08
gi|4885075 atonal homolog 1 [Homo sapiens] 56 5e-08
gi|68989258 neurogenin 3 [Homo sapiens] 55 1e-07
gi|5902108 SRY-box 21 [Homo sapiens] 54 2e-07
gi|4507741 twist [Homo sapiens] 54 2e-07
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 54 2e-07
gi|21553337 atonal homolog 7 [Homo sapiens] 54 2e-07
gi|239751178 PREDICTED: basic helix-loop-helix family, member a9... 53 3e-07
gi|239745666 PREDICTED: basic helix-loop-helix family, member a9... 53 3e-07
gi|226498192 atonal homolog 8 [Homo sapiens] 53 4e-07
gi|4885187 distal-less homeobox 5 [Homo sapiens] 51 2e-06
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 50 3e-06
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 50 3e-06
gi|111120318 NK6 transcription factor related, locus 1 [Homo sap... 48 1e-05
gi|7661892 REST corepressor 1 [Homo sapiens] 48 1e-05
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens] 48 1e-05
gi|6912372 forkhead box D3 [Homo sapiens] 47 2e-05
gi|18104952 T-box 1 isoform C [Homo sapiens] 47 2e-05
>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
sapiens]
Length = 323
Score = 647 bits (1670), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG 60
MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG
Sbjct: 1 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG 60
Query: 61 SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR 120
SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR
Sbjct: 61 SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR 120
Query: 121 MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH 180
MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH
Sbjct: 121 MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH 180
Query: 181 HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS 240
HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS
Sbjct: 181 HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS 240
Query: 241 ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV 300
ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV
Sbjct: 241 ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV 300
Query: 301 PPPHHHVSAMGAGSLPRLTSDAK 323
PPPHHHVSAMGAGSLPRLTSDAK
Sbjct: 301 PPPHHHVSAMGAGSLPRLTSDAK 323
>gi|28411948 oligodendrocyte transcription factor 3 [Homo sapiens]
Length = 272
Score = 272 bits (696), Expect = 3e-73
Identities = 159/323 (49%), Positives = 203/323 (62%), Gaps = 55/323 (17%)
Query: 1 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG 60
M+SD+S VSSR SSP+ D+++L + SST D ++
Sbjct: 1 MNSDSSSVSSRASSPDMDEMYLRDHHHRHHHHQESRLNSVSSTQGDMMQKM--------- 51
Query: 61 SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR 120
PG+ L +G K+ A SS K KKQ++E +LQQLRLKIN RERKR
Sbjct: 52 -----PGESLSRAGAKA-----------AGESSKYKIKKQLSEQDLQQLRLKINGRERKR 95
Query: 121 MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH 180
MHDLN+AMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLT+SLEEMKRLV EIYGGH
Sbjct: 96 MHDLNLAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTSSLEEMKRLVGEIYGGH 155
Query: 181 HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS 240
H+ FH CG + HSA HPA AA++ HP+ P A ++ A++ +S+
Sbjct: 156 HSAFH---CGTVGHSA------GHPAHAANSV------HPVHPILGGALSSGNASSPLSA 200
Query: 241 ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV 300
AS LP++G+IRPPH LLK+PS A LG GFQHW G+PCPC++CQ+
Sbjct: 201 AS-----LPAIGTIRPPHSLLKAPSTPPALQLG---------SGFQHWAGLPCPCTICQM 246
Query: 301 PPPHHHVSAMGAGSLPRLTSDAK 323
PPP H+SA+ ++ RL++++K
Sbjct: 247 PPP-PHLSALSTANMARLSAESK 268
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 138 bits (347), Expect = 8e-33
Identities = 91/191 (47%), Positives = 113/191 (59%), Gaps = 22/191 (11%)
Query: 57 GAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSR 116
G +G G G G SG S S S +SS+++SS+KK K+Q + LRL IN+R
Sbjct: 198 GGLGGGGGG-GSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQ------KALRLNINAR 250
Query: 117 ERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEI 176
ER+RMHDLN A+D LR V+PYAH PSVRKLSKIATLLLA+NYILM +LEEM+RLV+ +
Sbjct: 251 ERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYL 310
Query: 177 YGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAH---AAHHPAVHHPI---LPPAAAAAA 230
G A S P AA A AAA H A+ A +P LPPAA+
Sbjct: 311 NQGQAIS---------AASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCPE 361
Query: 231 AAAAAAAVSSA 241
A +VSS+
Sbjct: 362 KCALFNSVSSS 372
Score = 33.1 bits (74), Expect = 0.34
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 6/58 (10%)
Query: 227 AAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGG 284
A A AA S+A L G G+ PP GL +++ GGGGGSG+ G
Sbjct: 173 AGGGGAKAAEGCSNAHLHG------GASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSG 224
Score = 32.0 bits (71), Expect = 0.76
Identities = 41/144 (28%), Positives = 54/144 (37%), Gaps = 31/144 (21%)
Query: 179 GHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAV 238
G H G + L L A+T+ AA + P + + PP A
Sbjct: 4 GMHLGAAAAGEDDLFLHKSLSASTSKRLEAAFRSTPPGMDLSLAPPPRERPA-------- 55
Query: 239 SSASLPGSGLPSVGSIRP--PHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCS 296
SS+S P +G P P G + P GGGGGGS SGG GG+ P
Sbjct: 56 SSSSSP------LGCFEPADPEG-----AGLLLPPPGGGGGGSAGSGG-GGGGGVGVPGL 103
Query: 297 MCQVPPPHHHVSAMGAGSLPRLTS 320
+ V + G G P L+S
Sbjct: 104 L---------VGSAGVGGDPSLSS 118
>gi|237757328 oligodendrocyte transcription factor 1 [Homo sapiens]
Length = 271
Score = 109 bits (273), Expect = 3e-24
Identities = 102/297 (34%), Positives = 124/297 (41%), Gaps = 107/297 (36%)
Query: 26 SKGSSGSAFTGGTVSSSTPSDC-------PPELSAELRGAMGSAGAHPGDKLGGSGFKSS 78
S SS ++ T T SSST + PE AE G +GAHPG
Sbjct: 43 SSSSSSTSSTSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPG----------- 91
Query: 79 SSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREV-MPY 137
S + D K E + QQLR KINSRERKRM DLN+AMD LREV +PY
Sbjct: 92 -------------GSARPDAK---EEQQQQLRRKINSRERKRMQDLNLAMDALREVILPY 135
Query: 138 A----HGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLA 193
+ G RKLSKIATLLLARNYIL+L +SL+E++R + E G P+A L
Sbjct: 136 SAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGE-------GAGPAAPRLLL 188
Query: 194 HSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGS 253
PL AA PGS L + G+
Sbjct: 189 AGLPLLAAA-----------------------------------------PGSVLLAPGA 207
Query: 254 IRPPHGL---------LKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVP 301
+ PP L L P A GGG GG G C C++C+ P
Sbjct: 208 VGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGL-----------CTCAVCKFP 253
>gi|57529222 basic helix-loop-helix domain containing, class B, 4
[Homo sapiens]
Length = 225
Score = 105 bits (263), Expect = 4e-23
Identities = 60/107 (56%), Positives = 73/107 (68%), Gaps = 4/107 (3%)
Query: 105 ELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTN 164
E + LRL IN+RER+RMHDLN A+DGLR V+PYAH PSVRKLSKIATLLLA+NYILM
Sbjct: 97 EQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQ 156
Query: 165 SLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHA 211
+L+EM+RLV+ + G +A A P AT P +A A
Sbjct: 157 ALDEMRRLVAFLNQGQGLAAPVNA----APLTPFGQATVCPFSAGAA 199
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 73.2 bits (178), Expect = 3e-13
Identities = 75/227 (33%), Positives = 100/227 (44%), Gaps = 28/227 (12%)
Query: 98 KKQMTEPELQQLRL---KINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLL 154
K++MT+ L++ +L K N+RER RMHDLN A+D LR+V+P +KLSKI TL L
Sbjct: 108 KRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCY--SKTQKLSKIETLRL 165
Query: 155 ARNYILMLTNSLEEMKR--LVSEIYGGHHAGFHP-----SACGGLAHSAPLPAATAHPAA 207
A+NYI L+ L KR LVS + P + C L L A A
Sbjct: 166 AKNYIWALSEILRSGKRPDLVSYVQTLCKGLSQPTTNLVAGCLQLNSRNFLTEQGADGAG 225
Query: 208 AAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAA 267
H + P HP P + A A AA G G + ++R HG +
Sbjct: 226 RFHGSGGPFAMHPYPYPCSRLAGAQCQAAG-------GLGGGAAHALR-THGYCAAYETL 277
Query: 268 AAAPLGGGGGGSGASGGFQHWGGMPCPC------SMCQVPPPHHHVS 308
AA GGGG S ++ G + P S+ Q P H S
Sbjct: 278 YAA--AGGGGASPDYNSSEYEGPLSPPLCLNGNFSLKQDSSPDHEKS 322
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 66.6 bits (161), Expect = 3e-11
Identities = 72/248 (29%), Positives = 104/248 (41%), Gaps = 26/248 (10%)
Query: 16 EPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSA---ELRGAMGSAGAHPGDKLGG 72
E +D+ + S + +A T + S+ + P S RGA GA G G
Sbjct: 12 EEEDVLVLLGSASPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGA 71
Query: 73 SGFKSSS-----SSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIA 127
G + + S A A S + + + RLK N+RER RMH+LN A
Sbjct: 72 EGCRPARLLGLVHDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAA 131
Query: 128 MDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPS 187
+D LREV+P P KL+KI TL A NYI LT +L RL GG G P
Sbjct: 132 LDALREVLPTF--PEDAKLTKIETLRFAHNYIWALTETL----RLADHCGGG--GGGLP- 182
Query: 188 ACGGLAHSAPLPAATAHPAAAAHAAHHPA-------VHHPILPPAAAAAAAAAAAAAVSS 240
G L A L + AA + + P+ + P + ++ + + + +S
Sbjct: 183 --GALFSEAVLLSPGGASAALSSSGDSPSPASTWSCTNSPAPSSSVSSNSTSPYSCTLSP 240
Query: 241 ASLPGSGL 248
AS GS +
Sbjct: 241 ASPAGSDM 248
>gi|30039710 pancreas specific transcription factor, 1a [Homo
sapiens]
Length = 328
Score = 66.2 bits (160), Expect = 4e-11
Identities = 68/220 (30%), Positives = 93/220 (42%), Gaps = 22/220 (10%)
Query: 14 SPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGS 73
+P L L S G G GG + PP G+ S A+P G+
Sbjct: 73 APPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYP---CAGA 129
Query: 74 GFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLRE 133
S + S AAA++ ++ ++ +E ELQQLR N RER+RM +N A +GLR
Sbjct: 130 AVLSPGARLRG-LSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRS 188
Query: 134 VMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLA 193
+P P ++LSK+ TL LA YI N L E+ + + GG G CGG
Sbjct: 189 HIPTL--PYEKRLSKVDTLRLAIGYI----NFLSELVQADLPLRGGGAGG-----CGGPG 237
Query: 194 HSAPL----PAATAHPAAAAH-AAHHPAVHHPI--LPPAA 226
L P + A H P+ P LPP A
Sbjct: 238 GGGRLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLA 277
>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
Length = 356
Score = 64.7 bits (156), Expect = 1e-10
Identities = 61/171 (35%), Positives = 80/171 (46%), Gaps = 27/171 (15%)
Query: 98 KKQMTEPELQQL---RLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLL 154
KK+MT+ L++ R+K N+RER RMH LN A+D LR+V+P +KLSKI TL L
Sbjct: 88 KKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCY--SKTQKLSKIETLRL 145
Query: 155 ARNYILMLTNSLEEMKR--LVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAA 212
A+NYI L+ L K LVS F + C GL S P A
Sbjct: 146 AKNYIWALSEILRSGKSPDLVS---------FVQTLCKGL--SQPTTNLVAGCLQLNPRT 194
Query: 213 HHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKS 263
P + + P A+A+ V S GLPS PP+G + S
Sbjct: 195 FLPEQNQDMPP----HLPTASASFPVHPYSYQSPGLPS-----PPYGTMDS 236
>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
Length = 331
Score = 64.7 bits (156), Expect = 1e-10
Identities = 39/73 (53%), Positives = 48/73 (65%), Gaps = 5/73 (6%)
Query: 98 KKQMTEPELQQLR---LKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLL 154
KK+MT+ L++ R +K N+RER RMH LN A+D LR VMP +KLSKI TL L
Sbjct: 74 KKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCY--SKTQKLSKIETLRL 131
Query: 155 ARNYILMLTNSLE 167
ARNYI L+ LE
Sbjct: 132 ARNYIWALSEVLE 144
>gi|38455396 neurogenin 1 [Homo sapiens]
Length = 237
Score = 63.9 bits (154), Expect = 2e-10
Identities = 69/236 (29%), Positives = 91/236 (38%), Gaps = 21/236 (8%)
Query: 29 SSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSS 88
SSGS +G DC A L+ A ++G + G +S +
Sbjct: 17 SSGSDLSGFLTDEE---DC-----ARLQQAASASGPPAPARRGAPNISRASEVPGAQDDE 68
Query: 89 AAASSTKKDKKQMTEPELQQLR----LKINSRERKRMHDLNIAMDGLREVMPYAHGPSVR 144
+ + +E L LR +K N RER RMH+LN A+D LR V+P P
Sbjct: 69 QERRRRRGRTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLP--SFPDDT 126
Query: 145 KLSKIATLLLARNYILMLTNSLEEMKRLVSEIY--GGHHAGFHPSACGGLAHSAPLPAAT 202
KL+KI TL A NYI L +L RL + GG P C P PA+
Sbjct: 127 KLTKIETLRFAYNYIWALAETL----RLADQGLPGGGARERLLPPQCVPCLPGPPSPASD 182
Query: 203 AHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPH 258
A + AA P + P P A+ S SLP L + P H
Sbjct: 183 AESWGSGAAAASP-LSDPSSPAASEDFTYRPGDPVFSFPSLPKDLLHTTPCFIPYH 237
>gi|29126247 basic helix-loop-helix family, member a15 [Homo
sapiens]
Length = 189
Score = 58.9 bits (141), Expect = 6e-09
Identities = 34/62 (54%), Positives = 42/62 (67%), Gaps = 2/62 (3%)
Query: 108 QLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLE 167
Q RL+ N RER+RMH LN A LREV+P H + +KLSKI TL LA+NYI LT ++
Sbjct: 75 QRRLESNERERQRMHKLNNAFQALREVIP--HVRADKKLSKIETLTLAKNYIKSLTATIL 132
Query: 168 EM 169
M
Sbjct: 133 TM 134
>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
Length = 337
Score = 57.0 bits (136), Expect = 2e-08
Identities = 35/77 (45%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Query: 98 KKQMTEPELQQLRLK---INSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLL 154
KK+ T+ L++++ + N+RER RMH LN A+D LR+V+P +KLSKI TL L
Sbjct: 81 KKKTTKLRLERVKFRRQEANARERNRMHGLNDALDNLRKVVPCY--SKTQKLSKIETLRL 138
Query: 155 ARNYILMLTNSLEEMKR 171
A+NYI L+ L KR
Sbjct: 139 AKNYIWALSEILRIGKR 155
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 55.8 bits (133), Expect = 5e-08
Identities = 64/214 (29%), Positives = 86/214 (40%), Gaps = 41/214 (19%)
Query: 49 PELSAELRGAMGSAGAHPGDKLGGSG--FKSSSSSTSSSTSSA----------------- 89
PEL A S A P D++ G G + SS SSS S
Sbjct: 85 PELGA-------SEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVV 137
Query: 90 ---AASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKL 146
S + + +Q RL N+RER+RMH LN A D LR V+P + +KL
Sbjct: 138 DELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNND--KKL 195
Query: 147 SKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAA---TA 203
SK TL +A+ YI N+L E+ + S GG P++C H A+ A
Sbjct: 196 SKYETLQMAQIYI----NALSELLQTPS---GGEQPPPPPASCKSDHHHLRTAASYEGGA 248
Query: 204 HPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAA 237
A AA A PP + +A A+A
Sbjct: 249 GNATAAGAQQASGGSQRPTPPGSCRTRFSAPASA 282
>gi|68989258 neurogenin 3 [Homo sapiens]
Length = 214
Score = 54.7 bits (130), Expect = 1e-07
Identities = 31/57 (54%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
Query: 110 RLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSL 166
R K N RER RMH+LN A+D LR V+P P KL+KI TL A NYI LT +L
Sbjct: 85 RKKANDRERNRMHNLNSALDALRGVLPTF--PDDAKLTKIETLRFAHNYIWALTQTL 139
>gi|5902108 SRY-box 21 [Homo sapiens]
Length = 276
Score = 53.9 bits (128), Expect = 2e-07
Identities = 54/149 (36%), Positives = 65/149 (43%), Gaps = 19/149 (12%)
Query: 182 AGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAA---- 237
AG H A GGL + L A AAAA AA V P AAAAAAAAAAA +
Sbjct: 115 AGLHAGAGGGLVPESLL--ANPEKAAAAAAAAAARVFFPQSAAAAAAAAAAAAAGSPYSL 172
Query: 238 ------VSSASLPGSGLPSVGSIRPP---HGLLKSPSAAAAAPLGGGGGGSGASGGFQHW 288
++ S SGLP S+ P G +AAAAA GG + + +
Sbjct: 173 LDLGSKMAEISSSSSGLPYASSLGYPTAGAGAFHGAAAAAAAAAAAAGGHTHSHPSPGNP 232
Query: 289 GGM-PCPCSMCQVP---PPHHHVSAMGAG 313
G M PC CS P PP ++ G G
Sbjct: 233 GYMIPCNCSAWPSPGLQPPLAYILLPGMG 261
>gi|4507741 twist [Homo sapiens]
Length = 202
Score = 53.5 bits (127), Expect = 2e-07
Identities = 57/180 (31%), Positives = 69/180 (38%), Gaps = 40/180 (22%)
Query: 8 VSSRPSSP----------EPDDLFLPARSKG----------SSGSAFTGGTVSSSTPSDC 47
VSS P SP EPD P+ +G + G A GG
Sbjct: 5 VSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSRRSAGGGAGPGGAAGGGVGGGD 64
Query: 48 PPELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQ 107
P A+ + SAG G GG G SS + S ELQ
Sbjct: 65 EPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYE-----------------ELQ 107
Query: 108 QLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLE 167
R+ N RER+R LN A LR+++P PS KLSKI TL LA YI L L+
Sbjct: 108 TQRVMANVRERQRTQSLNEAFAALRKIIPTL--PS-DKLSKIQTLKLAARYIDFLYQVLQ 164
Score = 30.8 bits (68), Expect = 1.7
Identities = 22/65 (33%), Positives = 23/65 (35%), Gaps = 14/65 (21%)
Query: 228 AAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQH 287
A AA V PGS P G SA GGGGG+G GG
Sbjct: 50 AGPGGAAGGGVGGGDEPGS---------PAQGKRGKKSAGC-----GGGGGAGGGGGSSS 95
Query: 288 WGGMP 292
GG P
Sbjct: 96 GGGSP 100
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/142 (34%), Positives = 60/142 (42%), Gaps = 32/142 (22%)
Query: 187 SACGGLAHSAPLPAATA-HPAAAAHAAHHP--------AVHHPIL--------------P 223
+A G A +A P AT+ P A HP + HP L
Sbjct: 299 AAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGLNSAAS 358
Query: 224 PAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPL---------GG 274
AAAAAAAAAAA++ ++A P SG + S H + +AAAAA GG
Sbjct: 359 AAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAALGSRGGGGGG 418
Query: 275 GGGGSGASGGFQHWGGMPCPCS 296
GGGG G GG GG CS
Sbjct: 419 GGGGGGGGGGAGAGGGSDFGCS 440
Score = 40.0 bits (92), Expect = 0.003
Identities = 46/163 (28%), Positives = 61/163 (37%), Gaps = 39/163 (23%)
Query: 185 HPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLP 244
HP+ + AAT H+ H P ++P + AAAAAAAA+ AA +++S
Sbjct: 254 HPADPSFYTYMMTHAAATGSLPYPFHS-HVPLHYYPHVGVTAAAAAAAASGAAAAASS-- 310
Query: 245 GSGLPSVGSIRP---------PH----------------------GLLKSPSAAAAAPLG 273
P SIRP P+ GL + SAAAAA
Sbjct: 311 ----PFATSIRPLDTFRALSHPYSRPELLCSFRHPGLYQAPAAAAGLNSAASAAAAAAAA 366
Query: 274 GGGGGSGASGGFQHWGG-MPCPCSMCQVPPPHHHVSAMGAGSL 315
S A+ G GG PC C C +A A +L
Sbjct: 367 AAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAAAAAL 409
>gi|21553337 atonal homolog 7 [Homo sapiens]
Length = 152
Score = 53.5 bits (127), Expect = 2e-07
Identities = 40/94 (42%), Positives = 48/94 (51%), Gaps = 10/94 (10%)
Query: 110 RLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEM 169
RL N+RER+RM LN A D LR V+P +KLSK TL +A +YI+ LT L E
Sbjct: 42 RLAANARERRRMQGLNTAFDRLRRVVP--QWGQDKKLSKYETLQMALSYIMALTRILAEA 99
Query: 170 KRLVSE--IYGGHHAGFHPSACGGLAHSAPLPAA 201
+R SE G H F G H P P A
Sbjct: 100 ERFGSERDWVGLHCEHF------GRDHYLPFPGA 127
>gi|239751178 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 235
Score = 53.1 bits (126), Expect = 3e-07
Identities = 60/213 (28%), Positives = 83/213 (38%), Gaps = 19/213 (8%)
Query: 59 MGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRER 118
+G PG G G +S S + A + + + R+ N RER
Sbjct: 23 LGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKAR-------RMAANVRER 75
Query: 119 KRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYG 178
KR+ D N A + LR + H ++LSKIATL A + I L+ L
Sbjct: 76 KRILDYNEAFNALRRAL--RHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPC-- 131
Query: 179 GHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAV 238
GH P+A G + P A P+ A A P+V P P A+ A A
Sbjct: 132 GHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSV--PSAPRCASCPPHAPLARPS 189
Query: 239 SSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAP 271
+ A PG S GS R + P A++A P
Sbjct: 190 AVAEGPGLAQASGGSWR------RCPGASSAGP 216
>gi|239745666 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 235
Score = 53.1 bits (126), Expect = 3e-07
Identities = 60/213 (28%), Positives = 83/213 (38%), Gaps = 19/213 (8%)
Query: 59 MGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRER 118
+G PG G G +S S + A + + + R+ N RER
Sbjct: 23 LGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKAR-------RMAANVRER 75
Query: 119 KRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYG 178
KR+ D N A + LR + H ++LSKIATL A + I L+ L
Sbjct: 76 KRILDYNEAFNALRRAL--RHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPC-- 131
Query: 179 GHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAV 238
GH P+A G + P A P+ A A P+V P P A+ A A
Sbjct: 132 GHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSV--PSAPRCASCPPHAPLARPS 189
Query: 239 SSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAP 271
+ A PG S GS R + P A++A P
Sbjct: 190 AVAEGPGLAQASGGSWR------RCPGASSAGP 216
>gi|226498192 atonal homolog 8 [Homo sapiens]
Length = 321
Score = 52.8 bits (125), Expect = 4e-07
Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 17/115 (14%)
Query: 76 KSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVM 135
+ SS+S A A+S++ Q T RL N+RER R+H ++ A + LR+ +
Sbjct: 204 QDSSASPRKRPGEATAASSEIKALQQTR------RLLANARERTRVHTISAAFEALRKQV 257
Query: 136 P-YAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSAC 189
P Y++G +KLSK+A L +A NYIL L RL Y H+ S C
Sbjct: 258 PCYSYG---QKLSKLAILRIACNYILSLA-------RLADLDYSADHSNLSFSEC 302
>gi|4885187 distal-less homeobox 5 [Homo sapiens]
Length = 289
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/222 (22%), Positives = 98/222 (44%), Gaps = 12/222 (5%)
Query: 54 ELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKI 113
+ G GSAG++P + SS + + S+T + +K++TEPE++ + K
Sbjct: 76 QYHGVNGSAGSYPAKAYADYSYASSYHQYGGAYNRVP-SATNQPEKEVTEPEVRMVNGKP 134
Query: 114 NSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLL-LARNYI-LMLTNSLEEMKR 171
+ R + + L+ ++ + +++A L L + + + N ++K+
Sbjct: 135 KKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQNKRSKIKK 194
Query: 172 LVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHA-AHHPAVHHPILPPAAAAAA 230
++ G PS+ +A ++P A P ++ + +HHP H P +
Sbjct: 195 IMKN--GEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPP------TSNQ 246
Query: 231 AAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPL 272
+ A++ +SAS S S+ S PP G L+ P A A+ L
Sbjct: 247 SPASSYLENSASWYTSAASSINSHLPPPGSLQHPLALASGTL 288
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 50.1 bits (118), Expect = 3e-06
Identities = 39/107 (36%), Positives = 51/107 (47%), Gaps = 21/107 (19%)
Query: 186 PSACGGLAHSAP--LPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASL 243
P+A G S P L + +A P ++++ + P AAAAAAAAAAAAA SA
Sbjct: 426 PAASSGYESSTPPGLVSPSAEPQSSSNLS----------PAAAAAAAAAAAAAAAVSAVH 475
Query: 244 PGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGG 290
G G S G+ + + GGGGGG+G GG GG
Sbjct: 476 RGGGSGSGGA---------GGGSGGGSGSGGGGGGAGGGGGGSSGGG 513
Score = 31.6 bits (70), Expect = 1.00
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 9/64 (14%)
Query: 230 AAAAAAAAVSSASLPGSGLPSV-----GSIRPPHGLLKSPSAAAAAPLG----GGGGGSG 280
++ AA++ S++ PG PS ++ P + +AAAAA + GGG GSG
Sbjct: 424 SSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSG 483
Query: 281 ASGG 284
+GG
Sbjct: 484 GAGG 487
Score = 31.2 bits (69), Expect = 1.3
Identities = 27/66 (40%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 224 PAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGG--GSGA 281
P +AAAAAAAAA +A + P S R L +S +AP GG G G GA
Sbjct: 86 PGSAAAAAAAAALGPHAAHVGSYSGPPFNSTR--DFLFRSRGFGDSAPGGGQHGLFGPGA 143
Query: 282 SGGFQH 287
GG H
Sbjct: 144 -GGLHH 148
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 50.1 bits (118), Expect = 3e-06
Identities = 40/109 (36%), Positives = 47/109 (43%), Gaps = 11/109 (10%)
Query: 186 PSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPG 245
P GG H H P H P AAAAAAAAAA ++A+
Sbjct: 147 PDVKGGAGRDDLHAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAA--- 203
Query: 246 SGLPSV--GSIRPPHGLLKSP------SAAAAAPLGGGGGGSGASGGFQ 286
+ LPS+ G PP LL S + +AP G GGGG GA GG Q
Sbjct: 204 AHLPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQ 252
Score = 46.6 bits (109), Expect = 3e-05
Identities = 41/120 (34%), Positives = 48/120 (40%), Gaps = 20/120 (16%)
Query: 204 HPAAAAHAAHHPAVHHPILPP--------AAAAAAAAAAAAAVSSASLPGSGLPSVGSIR 255
H A H P + P PP AAAAAAAAAAAA ++A LP + G
Sbjct: 159 HAGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSM---AGGQQP 215
Query: 256 PPHGLLKSPS---------AAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHHH 306
PP LL S +A P GGGGG G + H G + HHH
Sbjct: 216 PPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHH 275
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/107 (33%), Positives = 42/107 (39%), Gaps = 6/107 (5%)
Query: 210 HAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAA 269
H H LP AAAAAAAAAAAA +S+ GS + GS + P P
Sbjct: 89 HMLSHAHQWVTALPHAAAAAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPD 148
Query: 270 APLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHH--HVSAMGAGS 314
G G A H G P + PPP H H GA +
Sbjct: 149 VKGGAGRDDLHAGTALHHRG----PPHLGPPPPPPHQGHPGGWGAAA 191
Score = 38.1 bits (87), Expect = 0.011
Identities = 25/56 (44%), Positives = 28/56 (50%), Gaps = 8/56 (14%)
Query: 235 AAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGG 290
A A S+ LPG+ L + GSI S AA A GGGGGG G GG GG
Sbjct: 2 ATAASNPYLPGNSLLAAGSI--------VHSDAAGAGGGGGGGGGGGGGGAGGGGG 49
>gi|111120318 NK6 transcription factor related, locus 1 [Homo
sapiens]
Length = 367
Score = 48.1 bits (113), Expect = 1e-05
Identities = 36/85 (42%), Positives = 50/85 (58%), Gaps = 8/85 (9%)
Query: 192 LAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSV 251
+A A LP+A+ ++++ ++ A +AAAAAAAAAAAA SS + +GLP
Sbjct: 109 VASGAALPSASPSGSSSSSSSSASASS-----ASAAAAAAAAAAAAASSPAGLLAGLPRF 163
Query: 252 GSIR---PPHGLLKSPSAAAAAPLG 273
S+ PP GL SPSAAA A +G
Sbjct: 164 SSLSPPPPPPGLYFSPSAAAVAAVG 188
Score = 35.0 bits (79), Expect = 0.090
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 17/100 (17%)
Query: 5 ASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAEL--------- 55
+S SS SSP P L + G TGG S +P P +LSA
Sbjct: 50 SSSSSSSSSSPSPP---LGTHNPGGLKPPATGGLSSLGSP---PQQLSAATPHGINDILS 103
Query: 56 RGAM--GSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASS 93
R +M S A P GS SSSS+++SS S+AAA++
Sbjct: 104 RPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAA 143
Score = 32.3 bits (72), Expect = 0.58
Identities = 35/127 (27%), Positives = 52/127 (40%), Gaps = 20/127 (15%)
Query: 178 GGHH-AGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAA 236
G H+ G P A GGL+ P + AA H + + P +P A+ AA +A+ +
Sbjct: 65 GTHNPGGLKPPATGGLSSLGSPPQQLS--AATPHGIND-ILSRPSMPVASGAALPSASPS 121
Query: 237 AVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCS 296
SS+S S S S + +AAA++P G G+P S
Sbjct: 122 GSSSSS---SSSASASSASAAAAAAAAAAAAASSPAG-------------LLAGLPRFSS 165
Query: 297 MCQVPPP 303
+ PPP
Sbjct: 166 LSPPPPP 172
Score = 32.0 bits (71), Expect = 0.76
Identities = 30/95 (31%), Positives = 41/95 (43%), Gaps = 5/95 (5%)
Query: 3 SDASLVSSRPSSP----EPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGA 58
S +S SS PS P P L PA G S +S++TP LS
Sbjct: 51 SSSSSSSSSPSPPLGTHNPGGLKPPATG-GLSSLGSPPQQLSAATPHGINDILSRPSMPV 109
Query: 59 MGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASS 93
A G S SSS+S SS++++AAA++
Sbjct: 110 ASGAALPSASPSGSSSSSSSSASASSASAAAAAAA 144
Score = 31.2 bits (69), Expect = 1.3
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 12/89 (13%)
Query: 187 SACGGLAHSAPLPAATAHPAAAAHAAHHPA-----------VHHPILPPAAAAAAAAAAA 235
S+ A ++ AA A AAAA AA PA + P PP + +AAA
Sbjct: 125 SSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAV 184
Query: 236 AAVSSASLPGSGLPSVGSIRPPHGLLKSP 264
AAV P + LP I P G+++SP
Sbjct: 185 AAVGRYPKPLAELPGRTPIFWP-GVMQSP 212
Score = 30.0 bits (66), Expect = 2.9
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 199 PAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPP 257
P A H A +PA + PP A +++++++ SS+ P G + G ++PP
Sbjct: 21 PLAALHSMAEMKTPLYPAAY----PPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPP 75
>gi|7661892 REST corepressor 1 [Homo sapiens]
Length = 482
Score = 47.8 bits (112), Expect = 1e-05
Identities = 36/97 (37%), Positives = 48/97 (49%), Gaps = 20/97 (20%)
Query: 200 AATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHG 259
AA + AAAA AA A P A+ AAA++A+AAA S+A+ P +G
Sbjct: 18 AAASASAAAASAAASAACASPAATAASGAAASSASAAAASAAAAPNNG------------ 65
Query: 260 LLKSPSAAAAAPLGGGG------GGSGASGGFQHWGG 290
++ S AAAAP G G SG+S +H GG
Sbjct: 66 --QNKSLAAAAPNGNSSSNSWEEGSSGSSSDEEHGGG 100
>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
Length = 193
Score = 47.8 bits (112), Expect = 1e-05
Identities = 39/129 (30%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Query: 114 NSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLV 173
N RER R+ +N+ LR+ +P HG + +KLSK+ TL A YI L L E +
Sbjct: 56 NERERNRVKLVNLGFQALRQHVP--HGGASKKLSKVETLRSAVEYIRALQRLLAEHDAVR 113
Query: 174 SEIYGG-HHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAA 232
+ + GG PSA G + P+ A+ P+ A+ + P P +A ++ +
Sbjct: 114 NALAGGLRPQAVRPSAPRGPPGTTPVAAS---PSRASSSPGRGGSSEPGSPRSAYSSDDS 170
Query: 233 AAAAAVSSA 241
A+S A
Sbjct: 171 GCEGALSPA 179
>gi|6912372 forkhead box D3 [Homo sapiens]
Length = 478
Score = 47.0 bits (110), Expect = 2e-05
Identities = 46/140 (32%), Positives = 55/140 (39%), Gaps = 30/140 (21%)
Query: 179 GHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAA-----------A 227
G G HP+A G A+S P AA A AAA + P+LPPA A
Sbjct: 272 GRPYGLHPAAAAG-AYSHPAAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKA 330
Query: 228 AA-----------------AAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAA 270
AA AAAAAA +A S + S S RP + AA
Sbjct: 331 AAFGSQLGPGLQLQLNSLGAAAAAAGTAGAAGTTASLIKSEPSARPSFSIENIIGGGPAA 390
Query: 271 PLGGGGGGSGASGGFQHWGG 290
P GG G+G +GG GG
Sbjct: 391 P-GGSAVGAGVAGGTGGSGG 409
Score = 38.9 bits (89), Expect = 0.006
Identities = 40/116 (34%), Positives = 47/116 (40%), Gaps = 26/116 (22%)
Query: 166 LEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPA 225
L E L+ + +G + A G L HPAAAA A HPA
Sbjct: 245 LREQTALMMQSFGAYSLAAAAGAAGPYGRPYGL-----HPAAAAGAYSHPA--------- 290
Query: 226 AAAAAAAAAAAAVSSASLPGSGLPSVGSIRP------PHGLLKSPSAAAAAPLGGG 275
AAAAAAAAAA A LP V + P P G L +AA + LG G
Sbjct: 291 AAAAAAAAAALQYPYA------LPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPG 340
Score = 32.3 bits (72), Expect = 0.58
Identities = 28/104 (26%), Positives = 37/104 (35%), Gaps = 18/104 (17%)
Query: 205 PAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSP 264
PAA H P P+ P AA A A V + G G + G
Sbjct: 63 PAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCK----GGVGGEEG----- 113
Query: 265 SAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHHHVS 308
A GG G GSG++GG P V PP+ +++
Sbjct: 114 ----GASGGGPGAGSGSAGGL-----APSKPKNSLVKPPYSYIA 148
Score = 28.5 bits (62), Expect = 8.4
Identities = 30/79 (37%), Positives = 33/79 (41%), Gaps = 17/79 (21%)
Query: 174 SEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHP-------AVHHPILP--- 223
S + G G S G A S P T +AA A H P A PIL
Sbjct: 394 SAVGAGVAGGTGGSGGGSTAQSFLRPPGTVQ-SAALMATHQPLSLSRTTATIAPILSVPL 452
Query: 224 ------PAAAAAAAAAAAA 236
PAA+AAAAAAAAA
Sbjct: 453 SGQFLQPAASAAAAAAAAA 471
>gi|18104952 T-box 1 isoform C [Homo sapiens]
Length = 495
Score = 47.0 bits (110), Expect = 2e-05
Identities = 34/80 (42%), Positives = 40/80 (50%), Gaps = 15/80 (18%)
Query: 180 HHAGFHPSAC-----GGLAHSAPLPAATA-----HPAAAAHAAHHPAVHHPILPPAAAAA 229
HH +P+A G + AP P HP A H HH HHP+ P AAAAA
Sbjct: 413 HHPYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPH--HH---HHPVSPAAAAAA 467
Query: 230 AAAAAAAAVSSASLPGSGLP 249
AAAAAAAA + S G+ P
Sbjct: 468 AAAAAAAAANMYSSAGAAPP 487
Score = 29.6 bits (65), Expect = 3.8
Identities = 27/85 (31%), Positives = 30/85 (35%), Gaps = 13/85 (15%)
Query: 198 LPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPP 257
L AA P AA+ A P PP AAAA A G PP
Sbjct: 21 LGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAP-------------GPPPPP 67
Query: 258 HGLLKSPSAAAAAPLGGGGGGSGAS 282
H +P+A AA G GAS
Sbjct: 68 HAYPFAPAAGAATSAAAEPEGPGAS 92
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.126 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,077,059
Number of Sequences: 37866
Number of extensions: 870926
Number of successful extensions: 16712
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 415
Number of HSP's successfully gapped in prelim test: 677
Number of HSP's that attempted gapping in prelim test: 8854
Number of HSP's gapped (non-prelim): 4781
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.