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Search of human proteins with 112734867
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
(1286 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|112734867 retinitis pigmentosa GTPase regulator interacting p... 2564 0.0
gi|189217904 RPGRIP1-like isoform b [Homo sapiens] 629 e-180
gi|118442834 RPGRIP1-like isoform a [Homo sapiens] 611 e-174
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 71 6e-12
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 67 8e-11
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 67 1e-10
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 66 2e-10
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 66 2e-10
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 65 3e-10
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 65 3e-10
gi|221139761 zinc finger protein 853 [Homo sapiens] 65 4e-10
gi|38044112 restin isoform b [Homo sapiens] 65 5e-10
gi|4506751 restin isoform a [Homo sapiens] 65 5e-10
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 65 5e-10
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 64 7e-10
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 64 7e-10
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 64 7e-10
gi|45439327 periplakin [Homo sapiens] 64 7e-10
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 64 1e-09
gi|21735548 centrosomal protein 2 [Homo sapiens] 63 2e-09
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 62 3e-09
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 62 3e-09
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 62 3e-09
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 62 3e-09
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 62 5e-09
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 62 5e-09
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 62 5e-09
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 62 5e-09
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 62 5e-09
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 61 6e-09
>gi|112734867 retinitis pigmentosa GTPase regulator interacting
protein 1 [Homo sapiens]
Length = 1286
Score = 2564 bits (6645), Expect = 0.0
Identities = 1286/1286 (100%), Positives = 1286/1286 (100%)
Query: 1 MSHLVDPTSGDLPVRDIDAIPLVLPASKGKNMKTQPPLSRMNREELEDSFFRLREDHMLV 60
MSHLVDPTSGDLPVRDIDAIPLVLPASKGKNMKTQPPLSRMNREELEDSFFRLREDHMLV
Sbjct: 1 MSHLVDPTSGDLPVRDIDAIPLVLPASKGKNMKTQPPLSRMNREELEDSFFRLREDHMLV 60
Query: 61 KELSWKQQDEIKRLRTTLLRLTAAGRDLRVAEEAAPLSETARRGQKAGWRQRLSMHQRPQ 120
KELSWKQQDEIKRLRTTLLRLTAAGRDLRVAEEAAPLSETARRGQKAGWRQRLSMHQRPQ
Sbjct: 61 KELSWKQQDEIKRLRTTLLRLTAAGRDLRVAEEAAPLSETARRGQKAGWRQRLSMHQRPQ 120
Query: 121 MHRLQGHFHCVGPASPRRAQPRVQVGHRQLHTAGAPVPEKPKRGPRDRLSYTAPPSFKEH 180
MHRLQGHFHCVGPASPRRAQPRVQVGHRQLHTAGAPVPEKPKRGPRDRLSYTAPPSFKEH
Sbjct: 121 MHRLQGHFHCVGPASPRRAQPRVQVGHRQLHTAGAPVPEKPKRGPRDRLSYTAPPSFKEH 180
Query: 181 ATNENRGEVASKPSELVSGSNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEEPPKS 240
ATNENRGEVASKPSELVSGSNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEEPPKS
Sbjct: 181 ATNENRGEVASKPSELVSGSNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEEPPKS 240
Query: 241 PEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEV 300
PEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEV
Sbjct: 241 PEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEV 300
Query: 301 QEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEF 360
QEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEF
Sbjct: 301 QEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEF 360
Query: 361 QERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAE 420
QERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAE
Sbjct: 361 QERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAE 420
Query: 421 LEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPA 480
LEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPA
Sbjct: 421 LEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPA 480
Query: 481 VLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEEL 540
VLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEEL
Sbjct: 481 VLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEEL 540
Query: 541 EAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPL 600
EAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPL
Sbjct: 541 EAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPL 600
Query: 601 SLCLETLPAHGDEDKVDISLLHQGENLFELHIHQAFLTSAALAQAGDTQPTTFCTYSFYD 660
SLCLETLPAHGDEDKVDISLLHQGENLFELHIHQAFLTSAALAQAGDTQPTTFCTYSFYD
Sbjct: 601 SLCLETLPAHGDEDKVDISLLHQGENLFELHIHQAFLTSAALAQAGDTQPTTFCTYSFYD 660
Query: 661 FETHCTPLSVGPQPLYDFTSQYVMETDSLFLHYLQEASARLDIHQAMASEHSTLAAGWIC 720
FETHCTPLSVGPQPLYDFTSQYVMETDSLFLHYLQEASARLDIHQAMASEHSTLAAGWIC
Sbjct: 661 FETHCTPLSVGPQPLYDFTSQYVMETDSLFLHYLQEASARLDIHQAMASEHSTLAAGWIC 720
Query: 721 FDRVLETVEKVHGLATLIGAGGEEFGVLEYWMRLRFPIKPSLQACNKRKKAQVYLSTDVL 780
FDRVLETVEKVHGLATLIGAGGEEFGVLEYWMRLRFPIKPSLQACNKRKKAQVYLSTDVL
Sbjct: 721 FDRVLETVEKVHGLATLIGAGGEEFGVLEYWMRLRFPIKPSLQACNKRKKAQVYLSTDVL 780
Query: 781 GGRKAQEEEFRSESWEPQNELWIEITKCCGLRSRWLGTQPSPYAVYRFFTFSDHDTAIIP 840
GGRKAQEEEFRSESWEPQNELWIEITKCCGLRSRWLGTQPSPYAVYRFFTFSDHDTAIIP
Sbjct: 781 GGRKAQEEEFRSESWEPQNELWIEITKCCGLRSRWLGTQPSPYAVYRFFTFSDHDTAIIP 840
Query: 841 ASNNPYFRDQARFPVLVTSDLDHYLRREALSIHVFDDEDLEPGSYLGRARVPLLPLAKNE 900
ASNNPYFRDQARFPVLVTSDLDHYLRREALSIHVFDDEDLEPGSYLGRARVPLLPLAKNE
Sbjct: 841 ASNNPYFRDQARFPVLVTSDLDHYLRREALSIHVFDDEDLEPGSYLGRARVPLLPLAKNE 900
Query: 901 SIKGDFNLTDPAEKPNGSIQVQLDWKFPYIPPESFLKPEAQTKGKDTKDSSKISSEEEKA 960
SIKGDFNLTDPAEKPNGSIQVQLDWKFPYIPPESFLKPEAQTKGKDTKDSSKISSEEEKA
Sbjct: 901 SIKGDFNLTDPAEKPNGSIQVQLDWKFPYIPPESFLKPEAQTKGKDTKDSSKISSEEEKA 960
Query: 961 SFPSQDQMASPEVPIEAGQYRSKRKPPHGGERKEKEHQVVSYSRRKHGKRIGVQGKNRME 1020
SFPSQDQMASPEVPIEAGQYRSKRKPPHGGERKEKEHQVVSYSRRKHGKRIGVQGKNRME
Sbjct: 961 SFPSQDQMASPEVPIEAGQYRSKRKPPHGGERKEKEHQVVSYSRRKHGKRIGVQGKNRME 1020
Query: 1021 YLSLNILNGNTPEQVNYTEWKFSETNSFIGDGFKNQHEEEEMTLSHSALKQKEPLHPVND 1080
YLSLNILNGNTPEQVNYTEWKFSETNSFIGDGFKNQHEEEEMTLSHSALKQKEPLHPVND
Sbjct: 1021 YLSLNILNGNTPEQVNYTEWKFSETNSFIGDGFKNQHEEEEMTLSHSALKQKEPLHPVND 1080
Query: 1081 KESSEQGSEVSEAQTTDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPEAEVMSDENIK 1140
KESSEQGSEVSEAQTTDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPEAEVMSDENIK
Sbjct: 1081 KESSEQGSEVSEAQTTDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPEAEVMSDENIK 1140
Query: 1141 QVYVEYKFYDLPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPQEQQGRRRFLFDMLNGQ 1200
QVYVEYKFYDLPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPQEQQGRRRFLFDMLNGQ
Sbjct: 1141 QVYVEYKFYDLPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPQEQQGRRRFLFDMLNGQ 1200
Query: 1201 DPDQGHLKFTVVSDPLDEEKKECEEVGYAYLQLWQILESGRDILEQELDIVSPEDLATPI 1260
DPDQGHLKFTVVSDPLDEEKKECEEVGYAYLQLWQILESGRDILEQELDIVSPEDLATPI
Sbjct: 1201 DPDQGHLKFTVVSDPLDEEKKECEEVGYAYLQLWQILESGRDILEQELDIVSPEDLATPI 1260
Query: 1261 GRLKVSLQAAAVLHAIYKEMTEDLFS 1286
GRLKVSLQAAAVLHAIYKEMTEDLFS
Sbjct: 1261 GRLKVSLQAAAVLHAIYKEMTEDLFS 1286
>gi|189217904 RPGRIP1-like isoform b [Homo sapiens]
Length = 1235
Score = 629 bits (1622), Expect = e-180
Identities = 435/1336 (32%), Positives = 697/1336 (52%), Gaps = 155/1336 (11%)
Query: 1 MSHLVDPTSGDLPVRD----IDAIPLVLPASKGKNMKTQPPLSRMNREELEDSFFRLRED 56
MS D T+GDLPV+D + + + S + MK++ +SR++REELED F RL ++
Sbjct: 1 MSGPTDETAGDLPVKDTGLNLFGMGGLQETSTTRTMKSRQAVSRVSREELEDRFLRLHDE 60
Query: 57 HMLVKELSWKQQDEIKRLRTTLLRLT--------------AAGRDLRVAEEAAPLSETAR 102
++L+K+ + KQ+D+IKR+ T L+RL GRD+ + E L E
Sbjct: 61 NILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRLGRDVEMEEMIEQLQEKVH 120
Query: 103 RGQKAGWRQRLSMHQRPQMHRLQGHFHCVGPASPRRAQPRVQVGHRQLHTAGAPVPEKPK 162
+K + + Q + QG+ Q R+ G R+ + A + E P+
Sbjct: 121 ELEKQNETLKNRLISAKQQLQTQGY----RQTPYNNVQSRINTGRRKAN-ENAGLQECPR 175
Query: 163 RGPRDR---LSYTAPPSFKEHATN---ENRGEVASKPSELVSGSNSIISFSSVISMAKPI 216
+G + + ++ T P F ++ + E RGE+
Sbjct: 176 KGIKFQDADVAETPHPMFTKYGNSLLEEARGEIR-------------------------- 209
Query: 217 GLCMPNSAHIMASNTMQVEEPPKSPE---KMWPKDENFEQRSSLEC-AQKAAELRASIKE 272
N +++ S Q+EE E + EN + S L+ Q+A + R++I++
Sbjct: 210 -----NLENVIQSQRGQIEELEHLAEILKTQLRRKENEIELSLLQLREQQATDQRSNIRD 264
Query: 273 KVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAE 332
VE+I+L K L E++ +L + + ++QE T L +H+AL+ +EL +
Sbjct: 265 NVEMIKLHKQLVEKSNALSAMEGKFIQLQEKQRT--------LRISHDALMANGDELNMQ 316
Query: 333 LKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSS 392
LKE+ K SL+ QL + + ++E Q+R+ DLEKER+LL +NYDKL +S + ++
Sbjct: 317 LKEQRLKCCSLEKQLHSMKFSERRIEELQDRINDLEKERELLKENYDKLYDS---AFSAA 373
Query: 393 SQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNI---- 448
+ W +L +QL+ Q++QL+ L ++L DK ++L L E+ QNE L E +
Sbjct: 374 HEEQW--KLKEQQLKVQIAQLETALKSDLTDKTEILDRLKTERDQNEKLVQENRELQLQY 431
Query: 449 LQKHKQEVELLQNAATISQPPDRQSEPATHPAVL------QENTQIEPSEPKNQE-EKKL 501
L++ +Q EL + +Q D ++ + +L Q+N + + E K L
Sbjct: 432 LEQKQQLDELKKRIKLYNQENDINADELSEALLLIKAQKEQKNGDLSFLVKVDSEINKDL 491
Query: 502 SQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
+ + ELQ +HAET ELEKTR+MLI+Q KIN YQ E+EA+ K +N +D++ K+E+
Sbjct: 492 ERSMRELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTRKMENLQQDYELKVEQY 551
Query: 562 TRLLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLL 621
LLD++ RI +LE QLKD+AYGT+ E +P ++ + L
Sbjct: 552 VHLLDIRAARIHKLEA-----------QLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHL 600
Query: 622 HQGENLFELHIHQAFLTSAALAQAGDTQPTTFCTYSFYDFETHCTPLSVGPQPLYDFTSQ 681
+GENLFE+HI++ +S L +GD +P TFCTY+FYDFE TP+ G P Y+FTSQ
Sbjct: 601 ERGENLFEIHINKVTFSSEVLQASGDKEPVTFCTYAFYDFELQTTPVVRGLHPEYNFTSQ 660
Query: 682 YVMETDSLFLHYLQEASARLDIHQAMASEHSTLAAGWICFDRVLETVEKVHGLATLIGAG 741
Y++ + LFL Y+Q+ + L++HQA ++E+ T+AA + F +LE ++ A+LIG
Sbjct: 661 YLVHVNDLFLQYIQKNTITLEVHQAYSTEYETIAACQLKFHEILEKSGRIFCTASLIGTK 720
Query: 742 GE--EFGVLEYWMRLRFPIKPSLQACNKRKKAQVYLSTDVLGGRKAQE---------EEF 790
G+ FG +EYW RLR P+ +++ +R KA Y++++ G Q +
Sbjct: 721 GDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKGPEHMQSLSQQAPKTAQLS 780
Query: 791 RSESWEPQ-NELWIEITKCCGLRSRWLGTQPSPYAVYRFFTFSDHDTAIIPASNNPYFRD 849
++S + NEL I I C L+SR QP PY VY+FF F+DHDTAIIP+SN+P F D
Sbjct: 781 STDSTDGNLNELHITIRCCNHLQSRASHLQPHPYVVYKFFDFADHDTAIIPSSNDPQFDD 840
Query: 850 QARFPVLVTSDLDHYLRREALSIHVFDDEDLEPGSYLGRARVPLLPLAKNESIKGDFNLT 909
FPV + DLD YL+ E+LS +VFDD D + Y+G+ VPL+ LA + I G F LT
Sbjct: 841 HMYFPVPMNMDLDRYLKSESLSFYVFDDSDTQENIYIGKVNVPLISLAHDRCISGIFELT 900
Query: 910 DPAEKPNGSIQVQLDWKFPYIPPESFLKPEAQTKGKDTKDSSKISSEEEKASFPSQDQMA 969
D + P G+I V L WKF Y+PP + T+D EE P Q
Sbjct: 901 DHQKHPAGTIHVILKWKFAYLPPSGSI---------TTEDLGNFIRSEE----PEVVQRL 947
Query: 970 SPEVPIEAGQYRSKRKPPHGGERKEKEHQVVSYSRRKHGKRIGVQGKNRMEYLSLNILNG 1029
P + + KP +K+ V H + +G S++ +
Sbjct: 948 PPASSVSTLVLAPRPKPRQRLTPVDKKVSFVDI--MPHQSDVSQEG-------SVDEVKE 998
Query: 1030 NTPEQVNYTEWKFSETNSFIGDGFKNQHEEEEMTLSHSALKQKEPLHPVNDKESSEQGSE 1089
NT + + + S + +G Q E+ + S + E L P +++ S
Sbjct: 999 NTEKM-----QQGKDDVSLLSEG---QLAEQSLASSEDETEITEDLEPEVEEDMS----- 1045
Query: 1090 VSEAQTTDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPEAEVMSDENIKQVYVEYKFY 1149
+DSDD I+P K K SEK+ IEI++L+ +++V D+ I++++VE +FY
Sbjct: 1046 -----ASDSDDCIIPGPISKNIKQPSEKIRIEIIALSL-NDSQVTMDDTIQRLFVECRFY 1099
Query: 1150 DLPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPQEQQGRRRFLFDMLNGQDPDQGHLKF 1209
LP ETPVSL KP++G+ +++++S VI +D + + +R L +L Q+ L+F
Sbjct: 1100 SLPAE--ETPVSLPKPKSGQWVYYNYSNVIYVDKENNKAKRDILKAILQKQEMPNRSLRF 1157
Query: 1210 TVVSD-PLDEEKKECEEVGYAYLQLWQILESGRDILEQELDIVSPEDLATPIGRLKVSLQ 1268
TVVSD P DE+ ECE++G A++ L + + GRD++EQ +D+ IG+L+V+++
Sbjct: 1158 TVVSDPPEDEQDLECEDIGVAHVDLADMFQEGRDLIEQNIDVFDARADGEGIGKLRVTVE 1217
Query: 1269 AAAVLHAIYKEMTEDL 1284
A L ++YK+ +DL
Sbjct: 1218 ALHALQSVYKQYRDDL 1233
>gi|118442834 RPGRIP1-like isoform a [Homo sapiens]
Length = 1315
Score = 611 bits (1575), Expect = e-174
Identities = 439/1395 (31%), Positives = 710/1395 (50%), Gaps = 193/1395 (13%)
Query: 1 MSHLVDPTSGDLPVRD----IDAIPLVLPASKGKNMKTQPPLSRMNREELEDSFFRLRED 56
MS D T+GDLPV+D + + + S + MK++ +SR++REELED F RL ++
Sbjct: 1 MSGPTDETAGDLPVKDTGLNLFGMGGLQETSTTRTMKSRQAVSRVSREELEDRFLRLHDE 60
Query: 57 HMLVKELSWKQQDEIKRLRTTLLRLT--------------AAGRDLRVAEEAAPLSETAR 102
++L+K+ + KQ+D+IKR+ T L+RL GRD+ + E L E
Sbjct: 61 NILLKQHARKQEDKIKRMATKLIRLVNDKKRYERVGGGPKRLGRDVEMEEMIEQLQEKVH 120
Query: 103 RGQKAGWRQRLSMHQRPQMHRLQGHFHCVGPASPRRAQPRVQVGHRQLHTAGAPVPEKPK 162
+K + + Q + QG+ Q R+ G R+ + A + E P+
Sbjct: 121 ELEKQNETLKNRLISAKQQLQTQGY----RQTPYNNVQSRINTGRRKAN-ENAGLQECPR 175
Query: 163 RGPRDR---LSYTAPPSFKEHATN---ENRGEVASKPSELVSGSNSIISFSSVISMAKPI 216
+G + + ++ T P F ++ + E RGE+
Sbjct: 176 KGIKFQDADVAETPHPMFTKYGNSLLEEARGEIR-------------------------- 209
Query: 217 GLCMPNSAHIMASNTMQVEEPPKSPE---KMWPKDENFEQRSSLEC-AQKAAELRASIKE 272
N +++ S Q+EE E + EN + S L+ Q+A + R++I++
Sbjct: 210 -----NLENVIQSQRGQIEELEHLAEILKTQLRRKENEIELSLLQLREQQATDQRSNIRD 264
Query: 273 KVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAE 332
VE+I+L K L E++ +L + + ++QE T L +H+AL+ +EL +
Sbjct: 265 NVEMIKLHKQLVEKSNALSAMEGKFIQLQEKQRT--------LRISHDALMANGDELNMQ 316
Query: 333 LKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSS 392
LKE+ K SL+ QL + + ++E Q+R+ DLEKER+LL +NYDKL +S + ++
Sbjct: 317 LKEQRLKCCSLEKQLHSMKFSERRIEELQDRINDLEKERELLKENYDKLYDS---AFSAA 373
Query: 393 SQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNI---- 448
+ W +L +QL+ Q++QL+ L ++L DK ++L L E+ QNE L E +
Sbjct: 374 HEEQW--KLKEQQLKVQIAQLETALKSDLTDKTEILDRLKTERDQNEKLVQENRELQLQY 431
Query: 449 LQKHKQEVELLQNAATISQPPDRQSEPATHPAVL------QENTQIEPSEPKNQE-EKKL 501
L++ +Q EL + +Q D ++ + +L Q+N + + E K L
Sbjct: 432 LEQKQQLDELKKRIKLYNQENDINADELSEALLLIKAQKEQKNGDLSFLVKVDSEINKDL 491
Query: 502 SQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
+ + ELQ +HAET ELEKTR+MLI+Q KIN YQ E+EA+ K +N +D++ K+E+
Sbjct: 492 ERSMRELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTRKMENLQQDYELKVEQY 551
Query: 562 TRLLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLL 621
LLD++ RI +LE QLKD+AYGT+ E +P ++ + L
Sbjct: 552 VHLLDIRAARIHKLEA-----------QLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHL 600
Query: 622 HQGENLFELHIHQAFLTSAALAQAGDTQPTTFCTYSFYDFETHCTPLSVGPQPLYDFTSQ 681
+GENLFE+HI++ +S L +GD +P TFCTY+FYDFE TP+ G P Y+FTSQ
Sbjct: 601 ERGENLFEIHINKVTFSSEVLQASGDKEPVTFCTYAFYDFELQTTPVVRGLHPEYNFTSQ 660
Query: 682 YVMETDSLFLHYLQEASARLDIHQAMASEHSTLAAGWICFDRVLETVEKVHGLATLIGAG 741
Y++ + LFL Y+Q+ + L++HQA ++E+ T+AA + F +LE ++ A+LIG
Sbjct: 661 YLVHVNDLFLQYIQKNTITLEVHQAYSTEYETIAACQLKFHEILEKSGRIFCTASLIGTK 720
Query: 742 GE--EFGVLEYWMRLRFPIKPSLQACNKRKKAQVYLSTDVLGGRKAQE---------EEF 790
G+ FG +EYW RLR P+ +++ +R KA Y++++ G Q +
Sbjct: 721 GDIPNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKGPEHMQSLSQQAPKTAQLS 780
Query: 791 RSESWEPQ-NELWIEITKCCGLRSRWLGTQPSPYAVYRFFTFSDHDTAIIPASNNPYFRD 849
++S + NEL I I C L+SR QP PY VY+FF F+DHDTAIIP+SN+P F D
Sbjct: 781 STDSTDGNLNELHITIRCCNHLQSRASHLQPHPYVVYKFFDFADHDTAIIPSSNDPQFDD 840
Query: 850 QARFPVLVTSDLDHYLRREALSIHVFDDEDLEPGSYLGRARVPLLPLAKNESIKGDFNLT 909
FPV + DLD YL+ E+LS +VFDD D + Y+G+ VPL+ LA + I G F LT
Sbjct: 841 HMYFPVPMNMDLDRYLKSESLSFYVFDDSDTQENIYIGKVNVPLISLAHDRCISGIFELT 900
Query: 910 DPAEKPNGSIQVQLDWKFPYIPPE---------SFLKPEAQTKGKDTKDSSKISSEEEKA 960
D + P G+I V L WKF Y+PP +F++ E + +S +S+ A
Sbjct: 901 DHQKHPAGTIHVILKWKFAYLPPSGSITTEDLGNFIRSEEPEVVQRLPPASSVST-LVLA 959
Query: 961 SFPSQDQMASPEVP----IEAGQYRSKRKPPHGGERKEKEHQVVSYSRRKHGKRIGVQGK 1016
P Q +P ++ ++S P +RKE +V +H I +
Sbjct: 960 PRPKPRQRLTPVDKKVSFVDIMPHQSDETSPPPEDRKEISPEV------EHIPEIEI-NM 1012
Query: 1017 NRMEYLSLNILNGNTPEQVNYTEWKFSETNSFIGDGFKNQHEEEEMTLSHSALKQKEPLH 1076
+ ++ G+ E TE K + + + Q E+ + S + E L
Sbjct: 1013 LTVPHVPKVSQEGSVDEVKENTE-KMQQGKDDVSLLSEGQLAEQSLASSEDETEITEDLE 1071
Query: 1077 PVNDKESSEQGSEVSEAQTTDSDDVIVP-------------------------------P 1105
P +++ S +DSDD I+P P
Sbjct: 1072 PEVEEDMS----------ASDSDDCIIPGPISKNIKQSLALSPGLGCSSAISAHCNFRLP 1121
Query: 1106 MSQKYPKA---------------DSEKMCIEIVSLAFYPEAEVMSDENIKQVYVEYKFYD 1150
S +P + SEK+ IEI++L+ +++V D+ I++++VE +FY
Sbjct: 1122 GSSDFPASASQVDGITGACHHTQPSEKIRIEIIALSL-NDSQVTMDDTIQRLFVECRFYS 1180
Query: 1151 LPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPQEQQGRRRFLFDMLNGQDPDQGHLKFT 1210
LP ETPVSL KP++G+ +++++S VI +D + + +R L +L Q+ L+FT
Sbjct: 1181 LPAE--ETPVSLPKPKSGQWVYYNYSNVIYVDKENNKAKRDILKAILQKQEMPNRSLRFT 1238
Query: 1211 VVSD-PLDEEKKECEEVGYAYLQLWQILESGRDILEQELDIVSPEDLATPIGRLKVSLQA 1269
VVSD P DE+ ECE++G A++ L + + GRD++EQ +D+ IG+L+V+++A
Sbjct: 1239 VVSDPPEDEQDLECEDIGVAHVDLADMFQEGRDLIEQNIDVFDARADGEGIGKLRVTVEA 1298
Query: 1270 AAVLHAIYKEMTEDL 1284
L ++YK+ +DL
Sbjct: 1299 LHALQSVYKQYRDDL 1313
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 71.2 bits (173), Expect = 6e-12
Identities = 99/431 (22%), Positives = 188/431 (43%), Gaps = 88/431 (20%)
Query: 243 KMWPKDENFEQRSSLECAQKAAELRASIKEKVELI----RLKKLLHERNASLVMTKAQLT 298
K+ P+ + + + E Q A L+ + EL+ +L++ + ERN + + ++
Sbjct: 2095 KVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVR 2154
Query: 299 EVQEAYETLLQKNQGILSAAHEALLK-QVNELRAELKEESKKAVSLKSQLE--------- 348
E+++A +K+ G + A E L+ Q+ R + + K+ +L+ QLE
Sbjct: 2155 ELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENK 2214
Query: 349 --DVSILQMTL----KEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPH------ 396
+V L M L KE R+++LE+E KL D+ +KL ++ +S S+Q
Sbjct: 2215 NEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGK 2274
Query: 397 -----WSNELIAEQLQQQVSQLQDQL-----DAELEDKRKVLLELSRE-----------K 435
E+ +QL +QV++LQ QL + +E+K +++ +L + K
Sbjct: 2275 FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVK 2334
Query: 436 AQNEDLKLEVTNILQKHKQEV-----ELLQNAATISQPPDRQSEPATHPAVLQENTQIEP 490
E+ ++ +++K +QE+ + NA ++S+ D V+ E +E
Sbjct: 2335 RNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQL--DVVIAEKLALEQ 2392
Query: 491 S-EPKNQEEKKLSQVLNELQVSHAETTLE---LEKTRDML-----ILQRKINVCY----- 536
E N+E + VL E + T E L++ R+ + I + +NV
Sbjct: 2393 QVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSK 2452
Query: 537 -QEELEAMMTKADNDNRDHKEKLERLTRLLDLKNN----------RIKQLEGILRSHDLP 585
+ ELE ++T+ D + LE T + N R+ QLE + + DL
Sbjct: 2453 DKPELEVVLTE------DALKSLENQTYFKSFEENGKGSIINLETRLLQLESTVSAKDLE 2506
Query: 586 TSE---QLKDV 593
++ Q+KD+
Sbjct: 2507 LTQCYKQIKDM 2517
Score = 52.0 bits (123), Expect = 4e-06
Identities = 74/346 (21%), Positives = 152/346 (43%), Gaps = 44/346 (12%)
Query: 249 ENFEQRSSLECAQKAAELRASIKEKVELIRLKK--LLHERNASLVMTKAQLTEVQEAYET 306
E + + Q+ L+ + +K+E ++ +K L+ ++N ++ +++++++ ++
Sbjct: 653 EKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLIL----EISKLKDLQQS 708
Query: 307 LLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKE----FQE 362
L+ ++ L K++ LR E KE+ ++ +L+ +KE QE
Sbjct: 709 LVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQE 768
Query: 363 RVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
+ LE E +L D K LE ML SQ E+L S D+ E
Sbjct: 769 KFAQLEAENSILKDE-KKTLEDMLKIHTPVSQ--------EERLIFLDSIKSKSKDSVWE 819
Query: 423 DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ---PPDRQSEPATHP 479
+ ++L+E +NEDLK + + +E+E +N + ++ + Q +
Sbjct: 820 KEIEILIE------ENEDLKQQCIQL----NEEIEKQRNTFSFAEKNFEVNYQELQEEYA 869
Query: 480 AVLQENTQIEPSEPKNQEE--KKLSQVLNELQVSHAE-TTLEL-----EKTRDMLILQRK 531
+L+ +E S+ K + E KL + EL + TT+++ ++ + + +
Sbjct: 870 CLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLE 929
Query: 532 INVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEG 577
+ +++ +M K + R EKLE RL DL + ++KQ G
Sbjct: 930 MGEVVEKDTTELMEKLEVTKR---EKLELSQRLSDL-SEQLKQKHG 971
Score = 49.7 bits (117), Expect = 2e-05
Identities = 88/430 (20%), Positives = 185/430 (43%), Gaps = 67/430 (15%)
Query: 205 SFSSVISMAKPIGLCMPNSAHIMASNTMQVEEPPKSPEKMWPK--DENFEQRSSLECA-- 260
S+S + P L M S +A ++EE + E+M E +Q E A
Sbjct: 144 SYSEQGAQDSPTHLEMMESE--LAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIK 201
Query: 261 -------QKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQG 313
Q A L+ + +EK E +R L E++ L + QL +A ETL
Sbjct: 202 QRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQL----QASETLRNSTHS 257
Query: 314 ILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKL 373
+A +Q+ + +L+E+ + + ED + +Q++ + + +V ++E+++K+
Sbjct: 258 STAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFT-MQISFLQEKIKVYEMEQDKKV 316
Query: 374 LNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSR 433
N N +++ E E I E+L ++ +E+++K L EL
Sbjct: 317 ENSNKEEIQEK---------------ETIIEELNTKI----------IEEEKKTL-ELKD 350
Query: 434 EKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEP 493
+ + L E+ + + QE++ ++ T S+ +RQS + Q +E +
Sbjct: 351 KLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSS----EEIKQLMGTVEELQK 406
Query: 494 KNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRD 553
+N ++ + + +Q ET +LE+ L+ +++ Y +++ M + R
Sbjct: 407 RNHKDSQFETDI--VQRMEQETQRKLEQ------LRAELDEMYGQQIVQMKQEL---IRQ 455
Query: 554 HKEKLERLTRLLDLKNNRIKQLEGILRSHDLPT--SEQLKDVAYGTRPLSLCLETLPAHG 611
H ++E ++K ++E LRS+ T +Q+K + L++ L+ +
Sbjct: 456 HMAQME------EMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQK 509
Query: 612 DEDKVDISLL 621
++ K ++ L+
Sbjct: 510 EKLKEELGLI 519
Score = 46.2 bits (108), Expect = 2e-04
Identities = 74/328 (22%), Positives = 142/328 (43%), Gaps = 43/328 (13%)
Query: 283 LHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEAL------LKQVNELRAELKEE 336
++E N L T +Q +++E +L++ + + + +Q+ R + E+
Sbjct: 495 INELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQ 554
Query: 337 SKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPH 396
K L V L+ + E ++LE + + NY LE ML+ ++
Sbjct: 555 ESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLE-MLEKEKNAVL-- 611
Query: 397 WSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQK----- 451
+ +AE + ++ +L+ QL E+ ELS+ K EDL++E ++K
Sbjct: 612 ---DRMAESQEAELERLRTQLLFSHEE------ELSKLK---EDLEIEHRINIEKLKDNL 659
Query: 452 ---HKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPK-------NQEEKKL 501
+KQ+++ LQN +SQ + + Q +E S+ K N + +++
Sbjct: 660 GIHYKQQIDGLQN--EMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEM 717
Query: 502 SQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
+ +NELQ E + EK + L + + E LE M + +ND ++ +LE
Sbjct: 718 TLQINELQ-KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAE 776
Query: 562 TRLLDLKNNRIKQLEGILRSHDLPTSEQ 589
+L + K LE +L+ H P S++
Sbjct: 777 NSIL---KDEKKTLEDMLKIH-TPVSQE 800
Score = 45.8 bits (107), Expect = 3e-04
Identities = 76/392 (19%), Positives = 167/392 (42%), Gaps = 65/392 (16%)
Query: 252 EQRSSLECAQ--KAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETL-- 307
E S LE A+ + +R S ++K E K E + +L E A E L
Sbjct: 1863 ETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEE-------LRERLHEESRAREQLAV 1915
Query: 308 -LQKNQGILSA-AHEALL--KQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQER 363
L K +G++ A E L +Q+ E + ++ + ++L+++ Q ++ QE
Sbjct: 1916 ELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQ---QQIQEE 1972
Query: 364 VEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELED 423
E L ++++ + + + +L ++ + + AE+++ + + L+ ++E+
Sbjct: 1973 RELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEE 2032
Query: 424 KRKVLLELSREK--------AQNEDLKLEVTNI---------------------LQKHKQ 454
+ +EL +EK QN+ L+ ++ + +QK +Q
Sbjct: 2033 QVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQ 2092
Query: 455 EVELLQNAATISQPPDRQSEP-ATH--------PAVLQENTQIEPS-EPKNQEEKKLSQV 504
+++++ IS+ R+ E A H +L Q++ + +N+E +KL
Sbjct: 2093 QLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKL--- 2149
Query: 505 LNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRD---HKEKLERL 561
E +V E L +E + ++ K + + +L+A D ++ +E+LE+
Sbjct: 2150 --EFRVRELEQALLVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQF 2207
Query: 562 TRLLDLKNNRIKQLEGILRSHDLPTSEQLKDV 593
L+ KN ++QL L ++ +L+++
Sbjct: 2208 REELENKNEEVQQLHMQLEIQKKESTTRLQEL 2239
Score = 40.8 bits (94), Expect = 0.008
Identities = 57/217 (26%), Positives = 98/217 (45%), Gaps = 24/217 (11%)
Query: 359 EFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHW----SNELIAEQLQQQVSQ-L 413
+F+E + L KE L ++ ++L S D D S E+ ++ V Q +
Sbjct: 1509 KFKEEFKPLSKE---LGEHGKEILLSNSDPHDIPESKDCVLTISEEMFSKDKTFIVRQSI 1565
Query: 414 QDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQS 473
D++ D + L+ L+ E Q ED++ E+ Q+H+Q ELL+ A + +RQ
Sbjct: 1566 HDEISVSSMDASRQLM-LNEE--QLEDMRQELVRQYQEHQQATELLRQAH--MRQMERQR 1620
Query: 474 EPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTL--ELEKTRDMLILQRK 531
E QE Q E + N++ + S + NE VS E L ELE + + + R+
Sbjct: 1621 ED-------QEQLQ-EEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGRE 1672
Query: 532 INVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLK 568
+C + + T+ N+N+ E+ + LD K
Sbjct: 1673 -KLCCELRNSSTQTQNGNENQGEVEEQTFKEKELDRK 1708
Score = 38.1 bits (87), Expect = 0.055
Identities = 52/205 (25%), Positives = 91/205 (44%), Gaps = 23/205 (11%)
Query: 242 EKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQ 301
E+M+ KD+ F R S+ + + AS +L+ ++ L + LV Q E Q
Sbjct: 1550 EEMFSKDKTFIVRQSIHDEISVSSMDASR----QLMLNEEQLEDMRQELVR---QYQEHQ 1602
Query: 302 EAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQ 361
+A E L Q AH +++ E + +L+EE K+ +Q + + + +
Sbjct: 1603 QATELLRQ--------AHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERER 1654
Query: 362 ERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAEL 421
+E+LE ++L +KL + +SS+Q NE E +Q + +LD +
Sbjct: 1655 VLLEELEALKQLSLAGREKL---CCELRNSSTQTQNGNENQGEVEEQTFK--EKELDRKP 1709
Query: 422 EDKRKVLLELSR---EKAQNEDLKL 443
ED +L R +KA N LK+
Sbjct: 1710 EDVPPEILSNERYALQKANNRLLKI 1734
Score = 37.7 bits (86), Expect = 0.071
Identities = 73/349 (20%), Positives = 143/349 (40%), Gaps = 39/349 (11%)
Query: 230 NTMQVEEPPKSPEKMWPKDENFEQ--RSSLECAQKAAELRASIK-EKVELIRLKKLLHER 286
N E KS E W ++ + RS ++ +L+ S++ +K ++L LL ++
Sbjct: 3199 NDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQ 3258
Query: 287 NASLVMTKAQLTEVQEAYETLLQKNQGI---LSAAHEALLKQVNELRAELKEESKKAVSL 343
L ++ ++ + Y+ L + QG L E+ ++ E+ + L E + L
Sbjct: 3259 KQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQL 3318
Query: 344 KS-----QLEDVSILQMTLKEFQERVEDLEKER-KLLNDNYDKLLESMLDSSD------- 390
+S Q + LKE Q+++E+ +LLN+ L+S+
Sbjct: 3319 QSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQV 3378
Query: 391 ------SSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLE 444
+ + + + +LQ +V LQ Q LE+KR+ + +L E + + + E
Sbjct: 3379 HRKTLQTEQEANTEGQKKMHELQSKVEDLQRQ----LEEKRQQVYKLDLEGQRLQGIMQE 3434
Query: 445 VTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQV 504
KQE+E + + +EP T ++ + T+ + K + E K S
Sbjct: 3435 F------QKQELEREEKRESRRILYQNLNEPTTW-SLTSDRTRNWVLQQKIEGETKESNY 3487
Query: 505 LNELQVSHAET--TLELEKTRDML-ILQRKINVCYQEELEAMMTKADND 550
++++ T ELE R L + K+ V Q+ E + + +D
Sbjct: 3488 AKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFETADD 3536
Score = 33.1 bits (74), Expect = 1.8
Identities = 67/314 (21%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 299 EVQEAYETLLQKNQGILSAAHEALLK---------------QVNELRAELKEESKKAVSL 343
E + A ++ +K +G+L A H ++ + ++ EE K ++
Sbjct: 2923 ESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINT 2982
Query: 344 KSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLL---ESMLDSSDSSSQPHWSNE 400
S L+D+ I +M L+ E V D + + +D +LL + + S + E
Sbjct: 2983 ISSLKDL-ITKMQLQREAE-VYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTE 3040
Query: 401 LIA--------------EQLQQQVSQLQDQLDA-ELEDKRKVLLELSREKAQNEDLKLEV 445
L A +++Q+Q + Q ++ + D+R +L E+ AQ K+ +
Sbjct: 3041 LTALGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITL 3100
Query: 446 TNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVL 505
+ K ELL+ I Q + E + +++ E E + E+ ++++
Sbjct: 3101 KREQESEKPSQELLE--YNIQQKQSQMLEMQVELSSMKDRA-TELQEQLSSEKMVVAELK 3157
Query: 506 NELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLL 565
+EL A+T LELE T L Q K + +ELEA + +D +++ L L
Sbjct: 3158 SEL----AQTKLELETT---LKAQHK----HLKELEAFRLEV----KDKTDEVHLLNDTL 3202
Query: 566 DLKNNRIKQLEGIL 579
+ + ++L+ L
Sbjct: 3203 ASEQKKSRELQWAL 3216
Score = 32.0 bits (71), Expect = 3.9
Identities = 37/186 (19%), Positives = 82/186 (44%), Gaps = 25/186 (13%)
Query: 333 LKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSS 392
L +E + +S+ SQ+ ++ + + K ++DLEK + L + + LES++ S
Sbjct: 1297 LPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTK--LEEQVQE-LESLISS---- 1349
Query: 393 SQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKH 452
LQQQ+ + + +AE+ +K L +S L V +++
Sbjct: 1350 -------------LQQQLKETEQNYEAEIHCLQKRLQAVSESTVPP---SLPVDSVVITE 1393
Query: 453 KQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQE--EKKLSQVLNELQV 510
+ + + + D E + V +E ++ E + QE E+++++V+ + +
Sbjct: 1394 SDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEETNIVKLLEKQYQEQLEEEVAKVIVSMSI 1453
Query: 511 SHAETT 516
+ A+ T
Sbjct: 1454 AFAQQT 1459
Score = 31.6 bits (70), Expect = 5.1
Identities = 50/225 (22%), Positives = 97/225 (43%), Gaps = 30/225 (13%)
Query: 264 AELRASIKEKVELIRLKKLLH----ERNASLVMTKAQLTEVQEAYETLLQKNQ--GILSA 317
AE KEK +L+ L+KLL ++ Q EV + L N+ G +
Sbjct: 2624 AEKNVLEKEK-KLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNE 2682
Query: 318 AHEALLKQVNELRAELKEESKKAVSLKSQL-----------EDVSILQMTLKEFQERVED 366
EAL + +AEL +KA L+ +L +D+S ++ L E +E++
Sbjct: 2683 L-EALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSI 2741
Query: 367 LEKERK----------LLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQ 416
LEKE + + KL +S+ +D + + SN+ ++ Q+ Q
Sbjct: 2742 LEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQ 2801
Query: 417 LDAELEDKRKVLLELSREKAQNEDL-KLEVTNILQKHKQEVELLQ 460
+ E+ +++ + + + + ++L E+ ++ +H E E L+
Sbjct: 2802 SECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLK 2846
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 67.4 bits (163), Expect = 8e-11
Identities = 89/380 (23%), Positives = 174/380 (45%), Gaps = 55/380 (14%)
Query: 242 EKMWPKDENFEQRSSLECAQKAAELRASIKEKV-------ELIRLKKLLHERNASLVMTK 294
E+ ++E+ Q+ LE A+L+ +E++ +L + KKLL +R A
Sbjct: 949 EEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFT--- 1005
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNE-LRAELKEESKKAVSLKSQLEDVSIL 353
LTE +E ++L + L HEA++ + E LR E K+ + + + D + L
Sbjct: 1006 TNLTEEEEKSKSLAK-----LKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDL 1060
Query: 354 QMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQL 413
+ E Q ++ +L+ + L ++L ++ + ++Q + + + I E L+ Q+S+L
Sbjct: 1061 SDQIAELQAQIAELKMQ---LAKKEEELQAALARVEEEAAQKNMALKKIRE-LESQISEL 1116
Query: 414 QDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNIL----------QKHKQEVELLQNAA 463
Q+ L++E + K + + E LK E+ + L K +QEV +L+
Sbjct: 1117 QEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTL 1176
Query: 464 TISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLN-ELQVSHAETTLELEK- 521
+ E TH A +QE Q + S+ + ++L Q + + A+ TLE E+
Sbjct: 1177 --------EEEAKTHEAQIQEMRQ-KHSQAVEELAEQLEQTKRVKANLEKAKQTLENERG 1227
Query: 522 ---TRDMLILQRKINVCY-----QEELEAMMTKADNDNRDHKEKLERLTRL-LDLKNNRI 572
++LQ K + + + +L+ + K + R E +++T+L ++L N
Sbjct: 1228 ELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDN--- 1284
Query: 573 KQLEGILRSHDLPTSEQLKD 592
+ G+L D +S+ KD
Sbjct: 1285 --VTGLLSQSDSKSSKLTKD 1302
Score = 54.3 bits (129), Expect = 7e-07
Identities = 101/486 (20%), Positives = 186/486 (38%), Gaps = 96/486 (19%)
Query: 179 EHATNENRGEVASKPSELVSGSNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEEPP 238
++A +R E ++ E + +S+A+ + M A + N E
Sbjct: 1459 KYAEERDRAEAEAREKE-----------TKALSLARALEEAMEQKAELERLNKQFRTE-- 1505
Query: 239 KSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLT 298
+ M KD+ + LE +++A E + + K +L L+ L + + + L
Sbjct: 1506 -MEDLMSSKDDVGKSVHELEKSKRALEQQVE-EMKTQLEELEDELQATEDAKLRLEVNLQ 1563
Query: 299 EVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKK---AVSLKSQLE------- 348
++ +E LQ + L++QV E+ AEL++E K+ AV+ + +LE
Sbjct: 1564 AMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
Query: 349 ----------DVSI-----LQMTLKEFQERVEDL--------------EKERKLLNDNYD 379
D +I LQ +K+ ++D EK+ K +
Sbjct: 1624 AHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMI 1683
Query: 380 KLLESMLDSSDSSSQPHWSNELIAEQ-----------------LQQQVSQLQDQLDAELE 422
+L E + + + Q + +A++ L+ +++QL+++L+ E
Sbjct: 1684 QLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQG 1743
Query: 423 DKRKVLLELSREKAQ----NEDLKLEVTNI---------LQKHKQEVEL-LQNAATISQP 468
+ + L + Q N DL LE ++ L++ +E+++ LQ +
Sbjct: 1744 NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKS 1803
Query: 469 PDRQSEPATHPAVLQENTQIEPSEPKNQ--------EEKKLSQVLNELQVSHAETTLELE 520
+ S A + Q Q++ + Q EKKL VL LQV E
Sbjct: 1804 KYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVL--LQVDDERRNAEQY 1861
Query: 521 KTR-DMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGIL 579
K + D + K EE E +A+ R + +LE T D N + L+ L
Sbjct: 1862 KDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKL 1921
Query: 580 RSHDLP 585
R DLP
Sbjct: 1922 RRGDLP 1927
Score = 50.1 bits (118), Expect = 1e-05
Identities = 74/334 (22%), Positives = 140/334 (41%), Gaps = 44/334 (13%)
Query: 248 DENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETL 307
D + S+ C + A E++ +++ +E L + E+ A+ + T +Q+ + L
Sbjct: 1368 DMKKKMEDSVGCLETAEEVKRKLQKDLE--GLSQRHEEKVAAYDKLEKTKTRLQQELDDL 1425
Query: 308 L----------------QKNQGILSAAHEALLKQVNELR----AELKEESKKAVSLKSQL 347
L QK L A + + + E R AE +E+ KA+SL L
Sbjct: 1426 LVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARAL 1485
Query: 348 EDV----SILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIA 403
E+ + L+ K+F+ +EDL + D+ K + + S + Q
Sbjct: 1486 EEAMEQKAELERLNKQFRTEMEDLMSSK----DDVGKSVHELEKSKRALEQQ-------V 1534
Query: 404 EQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNE-DLKLEVTNILQKHKQEVELLQ-- 460
E+++ Q+ +L+D+L A + K ++ + L KAQ E DL+ +K KQ V ++
Sbjct: 1535 EEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREM 1594
Query: 461 NAATISQPPDRQSEPATHPAVLQENTQIEPS-EPKNQEEKKLSQVLNELQVSHAETTLEL 519
A + R A + + +E + N+ + + L +LQ + EL
Sbjct: 1595 EAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMREL 1654
Query: 520 EKT---RDMLILQRKINVCYQEELEAMMTKADND 550
+ T R+ ++ Q K N + +EA M + +
Sbjct: 1655 DDTRASREEILAQAKENEKKLKSMEAEMIQLQEE 1688
Score = 47.8 bits (112), Expect = 7e-05
Identities = 93/417 (22%), Positives = 171/417 (41%), Gaps = 66/417 (15%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHER----NASLVMTKAQLTEVQEAYETL 307
E +L+ ELR+ +++V + LKK L E A + + + ++ E
Sbjct: 1147 ELEDTLDSTAAQQELRSKREQEVNI--LKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQ 1204
Query: 308 LQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDV-SILQMTLKEFQERVED 366
L++ + + + +A NE R EL E K + K E ++ L+E Q + +
Sbjct: 1205 LEQTKRVKANLEKAKQTLENE-RGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNE 1263
Query: 367 LEKERKLLNDNYDKL------LESMLDSSDSSS------------QPHWSNELIAEQLQQ 408
E+ R L D KL + +L SDS S Q + EL+ E+ +Q
Sbjct: 1264 GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQ 1323
Query: 409 QVS-------------QLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQE 455
++S ++QL+ E E K + +++ AQ D+K +K +
Sbjct: 1324 KLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK-------KKMEDS 1376
Query: 456 VELLQNAATISQPPDRQSEPAT--HPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHA 513
V L+ A + + + E + H + ++E ++ + Q+E L +L +L
Sbjct: 1377 VGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQE--LDDLLVDLD-HQR 1433
Query: 514 ETTLELEKTR---DMLILQRK-INVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKN 569
++ LEK + D L+ + K I+ Y EE + +A+ + R+ + K L R L+
Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERD----RAEAEAREKETKALSLARALEEAM 1489
Query: 570 NRIKQLEGILRS-----HDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLL 621
+ +LE + + DL +S+ DV L L +E K + L
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSSKD--DVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544
Score = 47.4 bits (111), Expect = 9e-05
Identities = 81/361 (22%), Positives = 151/361 (41%), Gaps = 88/361 (24%)
Query: 266 LRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQ 325
L+ S +E+ + + ++L+ R L + +LTE++ L+ + + + L+
Sbjct: 838 LQVSRQEEEMMAKEEELVKVREKQLA-AENRLTEMETLQSQLMAEKLQL-----QEQLQA 891
Query: 326 VNELRAELKEESKKAVSLKSQLEDVSI-LQMTLKEFQERVEDLEKERKLLNDNYDKLLES 384
EL AE +E + + K +LE++ L+ ++E +ER + L+ E+K
Sbjct: 892 ETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKK------------ 939
Query: 385 MLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLL-----ELSREKAQNE 439
++QQ + +L++QL+ E ++K+ L E +K + E
Sbjct: 940 --------------------KMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEE 979
Query: 440 DLKLEVTNI-LQKHKQEVE--LLQNAATISQPPDRQSEPA----THPAVLQE-NTQIEPS 491
+ LE N L K K+ +E + + +++ ++ A H A++ + ++
Sbjct: 980 QIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE 1039
Query: 492 EPKNQEEKK-----------LSQVLNELQVSHAETTLELEKTRDML-------------- 526
E + QE +K LS + ELQ AE ++L K + L
Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK 1099
Query: 527 -ILQRKINVC------YQEELE---AMMTKADNDNRDHKEKLERL-TRLLDLKNNRIKQL 575
+ +KI QE+LE A KA+ RD E+LE L T L D ++ Q
Sbjct: 1100 NMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ 1159
Query: 576 E 576
E
Sbjct: 1160 E 1160
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 66.6 bits (161), Expect = 1e-10
Identities = 97/429 (22%), Positives = 181/429 (42%), Gaps = 73/429 (17%)
Query: 235 EEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTK 294
EE E + +++N ++ E + ++R K E+ ++KKL+ E T+
Sbjct: 1501 EESIVGQETLRRENKNLQE----EISNLTNQVREGTKNLTEMEKVKKLIEEEK-----TE 1551
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLE-DVSIL 353
Q+T E E L++N+ + LL+ EL +L E+ ++ + + + + + L
Sbjct: 1552 VQVT--LEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSL 1609
Query: 354 QMTL-KEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQ 412
Q +L E + R+E ++K+ D L E L S ++ Q + + + QLQ Q+
Sbjct: 1610 QSSLDSEAKSRIEVTRLKKKMEED----LNEMELQLSCANRQVSEATKSLG-QLQIQIKD 1664
Query: 413 LQDQLD------------------------AELEDKRKVLLELSREKAQNEDLKLEVTNI 448
LQ QLD +ELED R + + R + +E+ LE T
Sbjct: 1665 LQMQLDDSTQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATER 1724
Query: 449 LQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNEL 508
+ + QN + +SQ +++ A +Q+ + E +N EEK +
Sbjct: 1725 IN-----LFYTQNTSLLSQKKKLEADVAR----MQKEAEEVVQECQNAEEKAKKAAIEAA 1775
Query: 509 QVSHA-----ETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTR 563
+S +T LE+TR+ + + Q+ L A +R +KLE
Sbjct: 1776 NLSEELKKKQDTIAHLERTRENM---EQTITDLQKRLAEAEQMALMGSRKQIQKLE---- 1828
Query: 564 LLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLLHQ 623
+R+++LEG L ++E + G R L C++ L +EDK ++S +
Sbjct: 1829 ------SRVRELEGELEGEIRRSAEAQR----GARRLERCIKELTYQAEEDKKNLSRMQT 1878
Query: 624 GENLFELHI 632
+ +L +
Sbjct: 1879 QMDKLQLKV 1887
Score = 58.9 bits (141), Expect = 3e-08
Identities = 82/358 (22%), Positives = 158/358 (44%), Gaps = 37/358 (10%)
Query: 247 KDENFEQRSSLECAQ----KAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQE 302
+DE FE + ++ + K+ + + + + KV+ L + + N + VQE
Sbjct: 956 EDECFELKKEIDDLETMLVKSEKEKRTTEHKVK--NLTEEVEFLNEDISKLNRAAKVVQE 1013
Query: 303 AYETLL------QKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMT 356
A++ L ++ LS A+ L +QV+EL L++E K ++ + +L L+
Sbjct: 1014 AHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHK---LEGN 1070
Query: 357 LKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE------QLQQQV 410
LK +E +E+LE ++ L + +L + L+ S +S+ L+A+ +LQ Q+
Sbjct: 1071 LKLNRESMENLESSQRHLAE---ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQI 1127
Query: 411 SQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPD 470
L+++L+AE + K+ E + DL + + ++E+ + T Q
Sbjct: 1128 KDLKEKLEAERTTRAKMERERADLTQDLADLNERLEEVGGSSLAQLEITKKQETKFQKLH 1187
Query: 471 RQSEPA-----THPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEK--TR 523
R E A T A L++ +E + Q E L QV +L+ ++ LE++ TR
Sbjct: 1188 RDMEEATLHFETTSASLKKRHADSLAELEGQVE-NLQQVKQKLEKDKSDLQLEVDDLLTR 1246
Query: 524 DMLILQRKIN-----VCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
+ + K N Y+E L K D + + + T+L +++LE
Sbjct: 1247 VEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLE 1304
Score = 52.4 bits (124), Expect = 3e-06
Identities = 80/374 (21%), Positives = 157/374 (41%), Gaps = 28/374 (7%)
Query: 210 ISMAKPIGLCMPNSAHIMASNTMQVEEPPKSPEKMWPKDE---NFEQRSSLECAQKAAEL 266
+++ + G N + I+ +E + K+ KDE NF ++ + L
Sbjct: 1554 VTLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSL 1613
Query: 267 RASIKEKVELIRLKKLLHE-RNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQ 325
+ K ++E+ RLKK + E N + +V EA ++L Q I + L
Sbjct: 1614 DSEAKSRIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDL--QMQLDD 1671
Query: 326 VNELRAELKEE----SKKAVSLKSQLEDVSILQMTLK-----EFQERVEDLEKERKLLND 376
+L ++LKE+ ++ L+S+LED+ LQ + +E +E E+
Sbjct: 1672 STQLNSDLKEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQ 1731
Query: 377 NYDKLLESMLDSSDSSSQPHWSNELI-----AEQLQQQVSQLQDQLDAELEDKRKVLLEL 431
N L + +D + + E++ AE+ ++ + L EL+ K+ + L
Sbjct: 1732 NTSLLSQKKKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHL 1791
Query: 432 SREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPS 491
R + E+++ +T+ LQK E E Q A S+ ++ E + +I S
Sbjct: 1792 ERTR---ENMEQTITD-LQKRLAEAE--QMALMGSRKQIQKLESRVRELEGELEGEIRRS 1845
Query: 492 EPKNQEEKKLSQVLNELQVSHAETTLELEKTR-DMLILQRKINVCYQEELEAMMTKADND 550
+ ++L + + EL E L + + M LQ K+ Y++++E T+A+
Sbjct: 1846 AEAQRGARRLERCIKELTYQAEEDKKNLSRMQTQMDKLQLKVQ-NYKQQVEVAETQANQY 1904
Query: 551 NRDHKEKLERLTRL 564
+K++ L +
Sbjct: 1905 LSKYKKQQHELNEV 1918
Score = 46.6 bits (109), Expect = 2e-04
Identities = 82/354 (23%), Positives = 161/354 (45%), Gaps = 36/354 (10%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
E+ + + ++ A+L + + E RL+++ A L +TK Q T+ Q+ + + +
Sbjct: 1137 ERTTRAKMERERADLTQDLADLNE--RLEEVGGSSLAQLEITKKQETKFQKLHRDMEEAT 1194
Query: 312 QGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLE-DVSILQMTLKEFQERVEDLEKE 370
+ + +L K+ + AEL+ + + +K +LE D S LQ+ + + RVE + +
Sbjct: 1195 LHFETTS-ASLKKRHADSLAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRA 1253
Query: 371 R---KLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKV 427
+ + L Y++ L D +Q +N+L A++ + + + LE+K +
Sbjct: 1254 KANAEKLCTLYEERLHEATAKLDKVTQ--LANDLAAQKTK--LWSESGEFLRRLEEKEAL 1309
Query: 428 LLELSREKA----QNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQ 483
+ +LSREK+ Q EDL+ + L+K + L +A Q R + +L+
Sbjct: 1310 INQLSREKSNFTRQIEDLRGQ----LEKETKSQSALAHAL---QKAQRDCD------LLR 1356
Query: 484 ENTQIEPSEPKNQEEKKLSQVLNEL-QVSHAETTLELEKTRDMLILQRKINVCYQEELEA 542
E + E E K + + LS+V E+ Q +++T D+ ++++ + QE EA
Sbjct: 1357 EQYE-EEQEVKAELHRTLSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEA 1415
Query: 543 M----MTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKD 592
M A + H+ +LE L DL +++ L L + + L D
Sbjct: 1416 MGVANARNASLERARHQLQLELGDALSDL--GKVRSAAARLDQKQLQSGKALAD 1467
Score = 41.6 bits (96), Expect = 0.005
Identities = 54/280 (19%), Positives = 128/280 (45%), Gaps = 25/280 (8%)
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
A + E + LL +Q + A LLK N + + K+ E++S L
Sbjct: 1466 ADWKQKHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQETLRRENKNLQEEISNLT 1525
Query: 355 MTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSS-----DSSSQPHWSNELI--AEQLQ 407
++E + + ++EK +KL+ + ++ ++ ++ + S H+ EL+ +L+
Sbjct: 1526 NQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAKAELE 1585
Query: 408 QQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ 467
+++S+ ++++ ++ + L ++EVT + +K ++++ ++ + +
Sbjct: 1586 RKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKSRIEVTRLKKKMEEDLNEMELQLSCA- 1644
Query: 468 PPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLI 527
+RQ AT ++ Q QI+ + + + +L+ L E QV+ AE R +
Sbjct: 1645 --NRQVSEAT-KSLGQLQIQIKDLQMQLDDSTQLNSDLKE-QVAVAE--------RRNSL 1692
Query: 528 LQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDL 567
LQ ++ E+L ++ + + R +E+L T ++L
Sbjct: 1693 LQSEL-----EDLRSLQEQTERGRRLSEEELLEATERINL 1727
Score = 33.9 bits (76), Expect = 1.0
Identities = 55/278 (19%), Positives = 113/278 (40%), Gaps = 33/278 (11%)
Query: 315 LSAAHEALLKQVNELRAELKEESKKAVSLKSQLE----DVSILQMTLKEFQERVEDLEKE 370
LS +Q+ +LR +L++E+K +L L+ D +L+ +E QE +L +
Sbjct: 1313 LSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRT 1372
Query: 371 RKLLNDNY--------DKLLESMLDSSDSSSQPHWSNELIAEQL------QQQVSQLQDQ 416
+N + +++ D D+ + + AE + + + + Q
Sbjct: 1373 LSKVNAEMVQWRMKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQ 1432
Query: 417 LDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPA 476
L EL D L ++ A+ + +L+ L KQ+ E Q SQ ++ +
Sbjct: 1433 LQLELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQ---KEVQAL 1489
Query: 477 THPAVLQENT---QIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKIN 533
+ + +NT I E +E K L + ++ L T E T+++ +++
Sbjct: 1490 STELLKLKNTYEESIVGQETLRRENKNLQEEISNL------TNQVREGTKNLTEMEKVKK 1543
Query: 534 VCYQEELEAMMTKADND---NRDHKEKLERLTRLLDLK 568
+ +E+ E +T + + R+ + L LL+ K
Sbjct: 1544 LIEEEKTEVQVTLEETEGALERNESKILHFQLELLEAK 1581
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 65.9 bits (159), Expect = 2e-10
Identities = 99/417 (23%), Positives = 184/417 (44%), Gaps = 56/417 (13%)
Query: 213 AKPIGLCMPNSAHIMASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKE 272
AKP GL +SA + S Q+EE + + FEQ++ AQ A E+ A IK
Sbjct: 124 AKPDGLVTDSSAELQ-SLEQQLEEAQTENFNIKQMKDLFEQKA----AQLATEI-ADIKS 177
Query: 273 KVELIRLKKLLHERNASLVMTKA--QLTEVQEAYETLLQKNQGILSAAHEALLKQVNELR 330
K + R + E+ + + + + T +Q+ LLQ+ A + L QV L
Sbjct: 178 KYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLM 237
Query: 331 -----------AELKEESKKAVS-----------LKSQL----EDVSILQMTLKEFQERV 364
+LK+E KK S L+S+L ++V++ L++ + V
Sbjct: 238 DNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSV 297
Query: 365 EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQ---VSQLQDQLDAEL 421
+L ++ + L +N K + + ++ S + I L Q+ QLQ +L A
Sbjct: 298 NELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASE 357
Query: 422 EDKRKVLLELSREKAQNEDLKLEVTNILQKH---KQEVELLQNAATISQPPDRQSEP--- 475
++ +ELS + + LK E++ + K+ K E + LQ + Q +
Sbjct: 358 TSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEIN 417
Query: 476 ATHPAVLQENTQIEPSEPKNQEEKKLS---------QVLN-ELQVSHAETTLELEKTRDM 525
H +L+ Q+ + + +E+++LS QV + +L++S E L+ EK +
Sbjct: 418 QLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK-EKVTNS 476
Query: 526 LILQRKINVCYQ--EELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILR 580
LQ +++ Q +E +A+ R+ + LE++ R + K+ +I+ LE +L+
Sbjct: 477 TELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQ 533
Score = 58.9 bits (141), Expect = 3e-08
Identities = 80/372 (21%), Positives = 152/372 (40%), Gaps = 59/372 (15%)
Query: 249 ENFEQRSSLECAQKAAELRASIKEKVEL--IRLKKLLHERNASLVMTKAQLTEVQEAYET 306
++ E ++S E A + + + + +EL L K L + T+ L + EA E+
Sbjct: 738 DSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALES 797
Query: 307 LLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSI-LQMTLKEFQE--- 362
+ QK L KQ E + ++ + K Q E+++ +Q T+ E Q+
Sbjct: 798 IKQK-----------LTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKM 846
Query: 363 RVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
E L E + D K+ +S+ +S + + + L++ +L+ QL ++E
Sbjct: 847 EKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQME 906
Query: 423 ----DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATH 478
+++++ L +EK + LKLE+ ++ + +L+Q T+ Q
Sbjct: 907 NTLKEQKELKKSLEKEKEASHQLKLELNSMQE------QLIQAQNTLKQ----------- 949
Query: 479 PAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQE 538
+EE++L +NEL+ S + ++E + L + +
Sbjct: 950 ---------------NEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELEN 994
Query: 539 ELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGIL---RSHDLPTSEQLKDVAY 595
+L+ +T+A + KEK+ L + KQL+ S L T + LK V
Sbjct: 995 KLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSV-- 1052
Query: 596 GTRPLSLCLETL 607
LSL E L
Sbjct: 1053 -EEKLSLAQEDL 1063
Score = 55.1 bits (131), Expect = 4e-07
Identities = 67/287 (23%), Positives = 126/287 (43%), Gaps = 17/287 (5%)
Query: 283 LHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVS 342
L E++ ++K + + Q+ Q LSA+ +L + + EL E+ +
Sbjct: 321 LEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSL----HRIHVELSEKGEATQK 376
Query: 343 LKSQLEDVSI----LQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWS 398
LK +L +V L+ K+ Q++ E+ E+ L ++L +L++ + H
Sbjct: 377 LKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLGEAHGR 436
Query: 399 NELIAEQLQQQVSQLQD--QLDAELEDKRKVLLELSREKAQNE-DLKLEVTNILQKHKQE 455
+ EQ Q +L D Q A+L+ K L E +EK N +L+ ++ Q+H QE
Sbjct: 437 ---LKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQH-QE 492
Query: 456 VELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKK-LSQVLNELQVSHAE 514
+ LQ + T + + ++ +I+ E Q+ K+ +S + E + +A+
Sbjct: 493 QQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAK 552
Query: 515 TTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
+T + LQ K N QE++ + K N + HK+ E L
Sbjct: 553 IQAGEGETAVLNQLQEK-NHTLQEQVTQLTEKLKNQSESHKQAQENL 598
Score = 46.6 bits (109), Expect = 2e-04
Identities = 48/244 (19%), Positives = 109/244 (44%), Gaps = 20/244 (8%)
Query: 322 LLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKL 381
L ++V +L+A LKEE + LK +LE LQ + V D E
Sbjct: 88 LRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAE----------- 136
Query: 382 LESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDL 441
L+S+ + + +++ + + + +Q+ +QL ++ A+++ K E++ E
Sbjct: 137 LQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEI-ADIKSK------YDEERSLREAA 189
Query: 442 KLEVTNILQKHKQEVELLQNAAT-ISQPPDRQSEPATHPAVLQENTQIE-PSEPKNQEEK 499
+ +VT + ++ +E ++Q+ T + Q P + ++Q T ++ + + +E +
Sbjct: 190 EQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESE 249
Query: 500 KLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLE 559
KL +LQ +A + + + R L + Y +EL+ + + + + ++ E
Sbjct: 250 KLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTE 309
Query: 560 RLTR 563
L +
Sbjct: 310 NLLK 313
Score = 41.2 bits (95), Expect = 0.006
Identities = 78/327 (23%), Positives = 139/327 (42%), Gaps = 59/327 (18%)
Query: 181 ATNENRGEVASKPS----ELVSGSNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEE 236
AT ++ V K S +L+S N I + + +I K + + A Q++E
Sbjct: 1044 ATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDS---AKKEQQLQE 1100
Query: 237 PPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQ 296
K+ + + K+++ +++ + K AE+ IK + E + KL E + + + +
Sbjct: 1101 RCKALQDI-QKEKSLKEKELVNEKSKLAEIE-EIKCRQEK-EITKLNEELKSHKLESIKE 1157
Query: 297 LTEVQEAYETLLQ--------------------KNQGILS----AAHEALLKQVNELRAE 332
+T +++A + L+Q +NQ IL E L K+ E A+
Sbjct: 1158 ITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAK 1217
Query: 333 LKEESK-KAVSLKSQLEDVSILQMTL-----------KEFQE---RVEDLEKERKLLNDN 377
L E K K V +K E+ + L M + KE+Q RV +LEK+ L
Sbjct: 1218 LHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGE 1277
Query: 378 YDKLLESMLDSSDSSS---QPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSRE 434
L ++ ++ D + E E+LQ +V +LQ +LD + + EL RE
Sbjct: 1278 IAVLEATVQNNQDERRALLERCLKGEGEIEKLQTKVLELQRKLD----NTTAAVQELGRE 1333
Query: 435 KAQNEDLKLEVTNILQKHKQEVELLQN 461
N+ L+++ T L + E +QN
Sbjct: 1334 ---NQSLQIKHTQALNRKWAEDNEVQN 1357
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 65.9 bits (159), Expect = 2e-10
Identities = 90/430 (20%), Positives = 184/430 (42%), Gaps = 53/430 (12%)
Query: 231 TMQVEEPPKSPEKMWPKDENFEQ-RSSLECAQKAAELRASIKEKVE--LIRLKKLLHERN 287
T Q EE + EK + FE+ +L AQK E R +K +++ + ++K E
Sbjct: 395 TTQGEELREQKEKS--ERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER 452
Query: 288 ASLVM----TKAQLTEV-----QEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESK 338
SL K ++ +V +E L + ++ L+ + L K++ E +E+ K
Sbjct: 453 ISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 512
Query: 339 KAVSLKSQLEDVSILQMTLKEFQERVEDLEKERK-LLNDNYDKLLESMLDSSDSSSQPHW 397
A+ KSQ E + I Q ++ +E+LE ++K +L ++ +KL + +
Sbjct: 513 VALE-KSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQE---------- 561
Query: 398 SNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSRE-KAQNEDLKLEVTNILQKHKQEV 456
AE + ++ +L+ L+ L++ + +L+ +A+ E+T +++KHK E+
Sbjct: 562 -----AETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTEL 616
Query: 457 ELLQNAA---------TISQPPDRQSEPATHPAVLQENTQIEPSEPKNQE--EKKLSQVL 505
E L++ + Q + E ++ T ++ E Q E+ + L
Sbjct: 617 ESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTL 676
Query: 506 NELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLL 565
+L V E + ++L + K+ +EEL + + D ++ + K++
Sbjct: 677 EKLDVKQTELESLSSELSEVLKARHKL----EEELSVLKDQTDKMKQELEAKMD------ 726
Query: 566 DLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLLHQGE 625
+ KN+ +Q++ I++ H++ K + L L L+ H E + + L
Sbjct: 727 EQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 786
Query: 626 NLFELHIHQA 635
E + QA
Sbjct: 787 KRSEGELQQA 796
Score = 61.6 bits (148), Expect = 5e-09
Identities = 83/379 (21%), Positives = 165/379 (43%), Gaps = 48/379 (12%)
Query: 231 TMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASL 290
T+ E E++ + + E+ L A+K +L +++ LI ++L ++ +
Sbjct: 310 TLLTSEKEALQEQLDERLQELEKIKDLHMAEKT-KLITQLRDAKNLI--EQLEQDKGMVI 366
Query: 291 VMTKAQLTEVQEAYE---TLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQL 347
TK Q+ E E E L+ ++ E L +Q + EE +KA+S +
Sbjct: 367 AETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT 426
Query: 348 EDVSILQMTLKEFQERVEDLEK----ERKLLNDNYDKLLESMLDSSDSSSQPHWSN---- 399
E+ + E E+++ +EK ER L ++ + ++D SS+ +
Sbjct: 427 EEAR--RKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 484
Query: 400 ---------ELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQ 450
+ + ++LQ + + Q+Q+ LE + L++S+EK Q E L LE
Sbjct: 485 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALE------ 538
Query: 451 KHKQEVELLQNA---ATISQPPDRQSEPATH-PAVLQENTQIEPS--EPKNQEEKKLSQV 504
E+EL + A + ++ D Q E T+ +L+ + +E S E KNQ + +
Sbjct: 539 ----ELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHL 594
Query: 505 LNELQVSHAETTLELEKTR-DMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTR 563
E + E T+ +EK + ++ L+ + + + E+L+ + + + +EK E+
Sbjct: 595 EAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQ--- 651
Query: 564 LLDLKNNRIKQLEGILRSH 582
K +K E I ++H
Sbjct: 652 ---EKETLLKDKEIIFQAH 667
Score = 55.1 bits (131), Expect = 4e-07
Identities = 83/407 (20%), Positives = 164/407 (40%), Gaps = 84/407 (20%)
Query: 225 HIMASNTMQVEEP-------PKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELI 277
HI+ VE P+S + + E E+ S C QK E + S+ ++ L
Sbjct: 1689 HILEEKLKSVESSQSETLIVPRSAKNVAAYTEQ-EEADSQGCVQKTYEEKISVLQR-NLT 1746
Query: 278 RLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEES 337
+KLL T + E++ Y+ L K + + HE + L+ EL+E++
Sbjct: 1747 EKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQ-SMIGHLQEELEEKN 1805
Query: 338 KKA----------------VSLKSQLEDV-SILQMTLKE-------FQERVEDLEK---- 369
KK + K LE+V +Q TL+E ++++++L+
Sbjct: 1806 KKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVR 1865
Query: 370 -------ERKLLNDNYDKL------------LESMLDSSDSSSQPHWSNELIAEQLQQQV 410
E + L Y+KL E + ++++ S+ H + ++ Q
Sbjct: 1866 QKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQH 1925
Query: 411 SQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPD 470
+ L+ +L +K+K+ E+ R L+ ++ + ++H+QE+E+L+ D
Sbjct: 1926 NDLEFKLAGAEREKQKLGKEIVR-------LQKDLRMLRKEHQQELEILKKEY------D 1972
Query: 471 RQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLI--- 527
++ E E + E + + + L Q++ E A+ ELE T I
Sbjct: 1973 QERE---------EKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKA 2023
Query: 528 --LQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRI 572
++ ++ +QEE ++ K + D K +R +LD + +
Sbjct: 2024 QEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM 2070
Score = 53.9 bits (128), Expect = 1e-06
Identities = 84/358 (23%), Positives = 155/358 (43%), Gaps = 65/358 (18%)
Query: 239 KSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLK----KLLHERNASLVMTK 294
K+ EK+ K E SS + + L+A K + EL LK K+ E A +
Sbjct: 674 KTLEKLDVKQTELESLSS----ELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM---D 726
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
Q Q+ ++++++++ + +AL Q+N+L LKE K
Sbjct: 727 EQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKH--------------- 771
Query: 355 MTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQ 414
LKE Q VE+LE + K + + S H + EQL +QLQ
Sbjct: 772 --LKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQL----AQLQ 825
Query: 415 DQLDAELEDKRKVLL-ELSREKAQNEDL-------KLEVTNILQK-HKQEVELLQNAATI 465
+L +LE +R +L +++ +AQ +D+ K++V +++Q+ KQ E+ Q ++
Sbjct: 826 QKL-LDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL 884
Query: 466 SQ-------PPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLE 518
+Q +++ E V +EN ++ E + +E + L+Q L+
Sbjct: 885 TQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLS------------ 932
Query: 519 LEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
K + IL + ++ + E M K ++ +E L++ +LLD + K+LE
Sbjct: 933 -AKEDSIHILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKK--KLLDQEAKLKKELE 986
Score = 51.2 bits (121), Expect = 6e-06
Identities = 82/384 (21%), Positives = 165/384 (42%), Gaps = 79/384 (20%)
Query: 278 RLKKLLHERNASLVMTKAQLTEVQEAYETLLQ---KNQGILSAAHEALLKQVNELRAELK 334
+L + L SL + + +E+ AY+ L + K QGILS + + L+++ ELR EL+
Sbjct: 138 QLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLRRIAELREELQ 197
Query: 335 --EESKKAV------SLKSQLEDVSILQMTLKEFQERVED-------------LEKERKL 373
+++KK + SL+ + + +S+LQ + ++R+ + LE + ++
Sbjct: 198 MDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEV 257
Query: 374 LNDNYD-------------------------KLLESMLDSSDSSSQPH--------WSNE 400
+ K E++L + Q H E
Sbjct: 258 FTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKE 317
Query: 401 LIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVE--L 458
+ EQL +++ +L+ D + +K K++ +L K E L+ + ++ + K+++ L
Sbjct: 318 ALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETL 377
Query: 459 LQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEE--------KKLSQVLNELQV 510
I+Q R + T L+E Q E SE EE +K + +L+
Sbjct: 378 EMKEEEIAQLRSRIKQMTTQGEELRE--QKEKSERAAFEELEKALSTAQKTEEARRKLKA 435
Query: 511 SHAETTLELEKT--RDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLK 568
E +EKT + + LQ++++ QE ++ M + +E++ +L +L + +
Sbjct: 436 EMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM-------KKSSEEQIAKLQKLHEKE 488
Query: 569 NNRIKQ-LEGILRSHDLPTSEQLK 591
R +Q L L++ + EQ+K
Sbjct: 489 LARKEQELTKKLQTREREFQEQMK 512
Score = 50.1 bits (118), Expect = 1e-05
Identities = 73/357 (20%), Positives = 147/357 (41%), Gaps = 55/357 (15%)
Query: 253 QRSSLECAQKAAELRASIKEKVE---------LIRLKKLLHERNASLV-MTKAQLTEVQE 302
+ ++LE +QK + A + E + + RL+ E+ SL + + +L +V
Sbjct: 986 ENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVIS 1045
Query: 303 AYETLLQKNQGILSAAHEALLKQVNELRAELKEE-----------SKKAVSLKSQ--LED 349
+E L + L HE L++ + AELK++ +K+ LK + +D
Sbjct: 1046 IWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQD 1105
Query: 350 VSI--LQMTLKEFQERVEDLEKERKLLNDNYDKL---LESMLDSSDSSSQPHWSNELIAE 404
++ LQ LK+ V L ++ L + +KL L L + + +++AE
Sbjct: 1106 TTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAE 1165
Query: 405 QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAAT 464
+ +++VS+L +L E+ + + + ED LE + ++ ++++
Sbjct: 1166 EDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTE 1225
Query: 465 ISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRD 524
A+L+ T +E N K + +L+ + TT K ++
Sbjct: 1226 ---------------ALLEAKT----NELINISSSKTNAILSRISHCQHRTT----KVKE 1262
Query: 525 MLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRS 581
L+ I C ELEA + + + ++ T L+ K N+IK ++ + S
Sbjct: 1263 ALL----IKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIES 1315
Score = 50.1 bits (118), Expect = 1e-05
Identities = 60/292 (20%), Positives = 131/292 (44%), Gaps = 26/292 (8%)
Query: 289 SLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNE---LRAELKEESKKAVSLKS 345
SLV K L + + + + ++ + L + +N ++ ELKE+ + SL
Sbjct: 1315 SLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSK 1374
Query: 346 QLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQ 405
QL D+++ E+ + RK ++ +LL+ + D S + + ++++
Sbjct: 1375 QLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLS-------FKVDTLSKE 1427
Query: 406 LQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATI 465
+ Q+ D + E K+K ++ + ++L++++ K K+ E + +
Sbjct: 1428 KISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE---LKSKEAYEKDEQINLL 1484
Query: 466 SQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDM 525
+ D+Q++ + + E + K++ EKK S + EL+ S +ELE
Sbjct: 1485 KEELDQQNKRF-------DCLKGEMEDDKSKMEKKESNLETELK-SQTARIMELEDH--- 1533
Query: 526 LILQRKINV-CYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
I Q+ I + E L+ + D ++++ +KL+ L + K+NR+K+ E
Sbjct: 1534 -ITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAE 1584
Score = 48.9 bits (115), Expect = 3e-05
Identities = 90/383 (23%), Positives = 160/383 (41%), Gaps = 70/383 (18%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
E R E A K AEL+ ++K+ I+ K+LL + K T LQ+
Sbjct: 1626 EDRLESESAAKLAELKRKAEQKIAAIK-KQLLSQMEEKEEQYKKGTESHLSELNTKLQER 1684
Query: 312 QGILSAAHEALLKQVNELRAE--LKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEK 369
+ + E L K V ++E + S K V+ ++ E+ K ++E++ L++
Sbjct: 1685 EREVHILEEKL-KSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR 1743
Query: 370 ERKLLNDNYDKLLESMLDSSDSSSQPH------WSNELI----AEQLQQQVSQLQDQLDA 419
+KLL+ + + + H + LI AE Q + + L
Sbjct: 1744 NLT----EKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQE 1799
Query: 420 ELEDKRK-----VLLELSREKAQNE-DLKLEVTNI---LQKHKQEVELL-----QNAATI 465
ELE+K K V + +E +N K + N+ +QK QE EL Q +
Sbjct: 1800 ELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKEL 1859
Query: 466 SQPPDRQSEPATHPAVLQENT--------------QIEPSE--PKNQEEKKLSQVL---- 505
RQ E H ++E T + +P+E +N EEK S ++
Sbjct: 1860 DSCLVRQKE--VHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL 1917
Query: 506 --------NELQVSHAETTLELEKT-RDMLILQRKINVC---YQEELEAMMTKADNDNRD 553
N+L+ A E +K ++++ LQ+ + + +Q+ELE + + D ++
Sbjct: 1918 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYD---QE 1974
Query: 554 HKEKLERLTRLLDLK-NNRIKQL 575
+EK+++ L+LK N+ +KQL
Sbjct: 1975 REEKIKQEQEDLELKHNSTLKQL 1997
Score = 43.1 bits (100), Expect = 0.002
Identities = 54/249 (21%), Positives = 111/249 (44%), Gaps = 34/249 (13%)
Query: 324 KQVNELRAELKEESKKAVSLKSQLED--------VSILQMTLKEFQERVEDLEKERKLLN 375
+Q+N L+ EL +++K+ LK ++ED S L+ LK R+ +LE
Sbjct: 1479 EQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKT 1538
Query: 376 DNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSRE- 434
+ L E + + + H EL+ Q Q +L ++ D +++ + +L L +
Sbjct: 1539 IEIESLNEVLKNYNQQKDIEH--KELV--QKLQHFQELGEEKDNRVKEAEEKILTLENQV 1594
Query: 435 ---KAQNEDLKLEVTNI---LQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQI 488
KA+ E K E+ ++ ++ ++E++ L++ +SE A A L+ +
Sbjct: 1595 YSMKAELETKKKELEHVNLSVKSKEEELKALEDRL--------ESESAAKLAELKRKAEQ 1646
Query: 489 EPSEPKNQ------EEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEA 542
+ + K Q E+++ + E +S T L+ E+ R++ IL+ K+ + E
Sbjct: 1647 KIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQ-EREREVHILEEKLKSVESSQSET 1705
Query: 543 MMTKADNDN 551
++ N
Sbjct: 1706 LIVPRSAKN 1714
Score = 41.2 bits (95), Expect = 0.006
Identities = 54/266 (20%), Positives = 115/266 (43%), Gaps = 22/266 (8%)
Query: 242 EKMWPKDENFEQRSSLECAQKAAEL---RASIKEKVELIRLKKLLHERNASLVMTKAQLT 298
E++ K E + ++ K EL K K L++ KLL A + +L
Sbjct: 1875 EELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQ-PKLLSNMEAQHNDLEFKLA 1933
Query: 299 EVQEAYETL------LQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSI 352
+ + L LQK+ +L H+ L+ + + + +EE K +L+ S
Sbjct: 1934 GAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNST 1993
Query: 353 LQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQ 412
L+ ++EF ++ E+E ++ + E++ + + ++ S++ QL +++++
Sbjct: 1994 LKQLMREFNTQLAQKEQELEM------TIKETINKAQEVEAELLESHQEETNQLLKKIAE 2047
Query: 413 LQDQLDAELEDKRKVLLELSRE-KAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDR 471
D L + ++L E A+ DL+ ++ + +K++Q++E +N D
Sbjct: 2048 KDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGN-----DN 2102
Query: 472 QSEPATHPAVLQENTQIEPSEPKNQE 497
+ + Q+ T I S+ K QE
Sbjct: 2103 VTIMELQTQLAQKTTLISDSKLKEQE 2128
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 65.5 bits (158), Expect = 3e-10
Identities = 97/439 (22%), Positives = 185/439 (42%), Gaps = 96/439 (21%)
Query: 243 KMWPKDENFEQRSSLECAQKAAELRASIKEKVELI----RLKKLLHERNASLVMTKAQLT 298
K+ P+ + + + E Q A L+ + EL+ +L++ + ERN + + ++
Sbjct: 2095 KVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVR 2154
Query: 299 EVQEAYETLLQKNQGILSAAHEALLKQVNELRAELK---------EESKKAVSLKSQLE- 348
E+++A Q + H ++ EL E++ + K+ +L+ QLE
Sbjct: 2155 ELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQ 2214
Query: 349 ----------DVSILQMTL----KEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQ 394
+V L M L KE R+++LE+E KL D+ +KL ++ +S S+Q
Sbjct: 2215 FREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQ 2274
Query: 395 PH-----------WSNELIAEQLQQQVSQLQDQL-----DAELEDKRKVLLELSRE---- 434
E+ +QL +QV++LQ QL + +E+K +++ +L +
Sbjct: 2275 DQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECL 2334
Query: 435 -------KAQNEDLKLEVTNILQKHKQEV-----ELLQNAATISQPPDRQSEPATHPAVL 482
K E+ ++ +++K +QE+ + NA ++S+ D V+
Sbjct: 2335 MSDQECVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQL--DVVI 2392
Query: 483 QENTQIEPS-EPKNQEEKKLSQVLNELQVSHAETTLE---LEKTRDML-----ILQRKIN 533
E +E E N+E + VL E + T E L++ R+ + I + +N
Sbjct: 2393 AEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENSVN 2452
Query: 534 VCY------QEELEAMMTKADNDNRDHKEKLERLTRLLDLKNN----------RIKQLEG 577
V + ELE ++T+ D + LE T + N R+ QLE
Sbjct: 2453 VAIDHLSKDKPELEVVLTE------DALKSLENQTYFKSFEENGKGSIINLETRLLQLES 2506
Query: 578 ILRSHDLPTSE---QLKDV 593
+ + DL ++ Q+KD+
Sbjct: 2507 TVSAKDLELTQCYKQIKDM 2525
Score = 52.0 bits (123), Expect = 4e-06
Identities = 74/346 (21%), Positives = 152/346 (43%), Gaps = 44/346 (12%)
Query: 249 ENFEQRSSLECAQKAAELRASIKEKVELIRLKK--LLHERNASLVMTKAQLTEVQEAYET 306
E + + Q+ L+ + +K+E ++ +K L+ ++N ++ +++++++ ++
Sbjct: 653 EKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLIL----EISKLKDLQQS 708
Query: 307 LLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKE----FQE 362
L+ ++ L K++ LR E KE+ ++ +L+ +KE QE
Sbjct: 709 LVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQE 768
Query: 363 RVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
+ LE E +L D K LE ML SQ E+L S D+ E
Sbjct: 769 KFAQLEAENSILKDE-KKTLEDMLKIHTPVSQ--------EERLIFLDSIKSKSKDSVWE 819
Query: 423 DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ---PPDRQSEPATHP 479
+ ++L+E +NEDLK + + +E+E +N + ++ + Q +
Sbjct: 820 KEIEILIE------ENEDLKQQCIQL----NEEIEKQRNTFSFAEKNFEVNYQELQEEYA 869
Query: 480 AVLQENTQIEPSEPKNQEE--KKLSQVLNELQVSHAE-TTLEL-----EKTRDMLILQRK 531
+L+ +E S+ K + E KL + EL + TT+++ ++ + + +
Sbjct: 870 CLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAETLE 929
Query: 532 INVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEG 577
+ +++ +M K + R EKLE RL DL + ++KQ G
Sbjct: 930 MGEVVEKDTTELMEKLEVTKR---EKLELSQRLSDL-SEQLKQKHG 971
Score = 49.7 bits (117), Expect = 2e-05
Identities = 88/430 (20%), Positives = 185/430 (43%), Gaps = 67/430 (15%)
Query: 205 SFSSVISMAKPIGLCMPNSAHIMASNTMQVEEPPKSPEKMWPK--DENFEQRSSLECA-- 260
S+S + P L M S +A ++EE + E+M E +Q E A
Sbjct: 144 SYSEQGAQDSPTHLEMMESE--LAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIK 201
Query: 261 -------QKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQG 313
Q A L+ + +EK E +R L E++ L + QL +A ETL
Sbjct: 202 QRDGIITQLTANLQQARREKDETMREFLELTEQSQKLQIQFQQL----QASETLRNSTHS 257
Query: 314 ILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKL 373
+A +Q+ + +L+E+ + + ED + +Q++ + + +V ++E+++K+
Sbjct: 258 STAADLLQAKQQILTHQQQLEEQDHLLEDYQKKKEDFT-MQISFLQEKIKVYEMEQDKKV 316
Query: 374 LNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSR 433
N N +++ E E I E+L ++ +E+++K L EL
Sbjct: 317 ENSNKEEIQEK---------------ETIIEELNTKI----------IEEEKKTL-ELKD 350
Query: 434 EKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEP 493
+ + L E+ + + QE++ ++ T S+ +RQS + Q +E +
Sbjct: 351 KLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSS----EEIKQLMGTVEELQK 406
Query: 494 KNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRD 553
+N ++ + + +Q ET +LE+ L+ +++ Y +++ M + R
Sbjct: 407 RNHKDSQFETDI--VQRMEQETQRKLEQ------LRAELDEMYGQQIVQMKQEL---IRQ 455
Query: 554 HKEKLERLTRLLDLKNNRIKQLEGILRSHDLPT--SEQLKDVAYGTRPLSLCLETLPAHG 611
H ++E ++K ++E LRS+ T +Q+K + L++ L+ +
Sbjct: 456 HMAQME------EMKTRHKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQK 509
Query: 612 DEDKVDISLL 621
++ K ++ L+
Sbjct: 510 EKLKEELGLI 519
Score = 46.2 bits (108), Expect = 2e-04
Identities = 74/328 (22%), Positives = 142/328 (43%), Gaps = 43/328 (13%)
Query: 283 LHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEAL------LKQVNELRAELKEE 336
++E N L T +Q +++E +L++ + + + +Q+ R + E+
Sbjct: 495 INELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQ 554
Query: 337 SKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPH 396
K L V L+ + E ++LE + + NY LE ML+ ++
Sbjct: 555 ESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLE-MLEKEKNAVL-- 611
Query: 397 WSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQK----- 451
+ +AE + ++ +L+ QL E+ ELS+ K EDL++E ++K
Sbjct: 612 ---DRMAESQEAELERLRTQLLFSHEE------ELSKLK---EDLEIEHRINIEKLKDNL 659
Query: 452 ---HKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPK-------NQEEKKL 501
+KQ+++ LQN +SQ + + Q +E S+ K N + +++
Sbjct: 660 GIHYKQQIDGLQN--EMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEM 717
Query: 502 SQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
+ +NELQ E + EK + L + + E LE M + +ND ++ +LE
Sbjct: 718 TLQINELQ-KEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAE 776
Query: 562 TRLLDLKNNRIKQLEGILRSHDLPTSEQ 589
+L + K LE +L+ H P S++
Sbjct: 777 NSIL---KDEKKTLEDMLKIH-TPVSQE 800
Score = 46.2 bits (108), Expect = 2e-04
Identities = 76/395 (19%), Positives = 171/395 (43%), Gaps = 63/395 (15%)
Query: 252 EQRSSLECAQ--KAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETL-- 307
E S LE A+ + +R S ++K E K E + +L E A E L
Sbjct: 1863 ETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEE-------LRERLHEESRAREQLAV 1915
Query: 308 -LQKNQGILSA-AHEALL--KQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQER 363
L K +G++ A E L +Q+ E + ++ + ++L+++ Q ++ QE
Sbjct: 1916 ELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQ---QQIQEE 1972
Query: 364 VEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELED 423
E L ++++ + + + +L ++ + + AE+++ + + L+ ++E+
Sbjct: 1973 RELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEE 2032
Query: 424 KRKVLLELSREK--------AQNEDLKLEVTNI---------------------LQKHKQ 454
+ +EL +EK QN+ L+ ++ + +QK +Q
Sbjct: 2033 QVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQ 2092
Query: 455 EVELLQNAATISQPPDRQSEP-ATH--------PAVLQENTQIEPS-EPKNQEEKKLSQV 504
+++++ IS+ R+ E A H +L Q++ + +N+E +KL
Sbjct: 2093 QLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFR 2152
Query: 505 LNELQ---VSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRD---HKEKL 558
+ EL+ + A+T ++E + ++ K + + +L+A D ++ +E+L
Sbjct: 2153 VRELEQALLVSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQL 2212
Query: 559 ERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDV 593
E+ L+ KN ++QL L ++ +L+++
Sbjct: 2213 EQFREELENKNEEVQQLHMQLEIQKKESTTRLQEL 2247
Score = 40.8 bits (94), Expect = 0.008
Identities = 57/217 (26%), Positives = 98/217 (45%), Gaps = 24/217 (11%)
Query: 359 EFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHW----SNELIAEQLQQQVSQ-L 413
+F+E + L KE L ++ ++L S D D S E+ ++ V Q +
Sbjct: 1509 KFKEEFKPLSKE---LGEHGKEILLSNSDPHDIPESKDCVLTISEEMFSKDKTFIVRQSI 1565
Query: 414 QDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQS 473
D++ D + L+ L+ E Q ED++ E+ Q+H+Q ELL+ A + +RQ
Sbjct: 1566 HDEISVSSMDASRQLM-LNEE--QLEDMRQELVRQYQEHQQATELLRQAH--MRQMERQR 1620
Query: 474 EPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTL--ELEKTRDMLILQRK 531
E QE Q E + N++ + S + NE VS E L ELE + + + R+
Sbjct: 1621 ED-------QEQLQ-EEIKRLNRQLAQRSSIDNENLVSERERVLLEELEALKQLSLAGRE 1672
Query: 532 INVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLK 568
+C + + T+ N+N+ E+ + LD K
Sbjct: 1673 -KLCCELRNSSTQTQNGNENQGEVEEQTFKEKELDRK 1708
Score = 38.1 bits (87), Expect = 0.055
Identities = 52/205 (25%), Positives = 91/205 (44%), Gaps = 23/205 (11%)
Query: 242 EKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQ 301
E+M+ KD+ F R S+ + + AS +L+ ++ L + LV Q E Q
Sbjct: 1550 EEMFSKDKTFIVRQSIHDEISVSSMDASR----QLMLNEEQLEDMRQELVR---QYQEHQ 1602
Query: 302 EAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQ 361
+A E L Q AH +++ E + +L+EE K+ +Q + + + +
Sbjct: 1603 QATELLRQ--------AHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERER 1654
Query: 362 ERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAEL 421
+E+LE ++L +KL + +SS+Q NE E +Q + +LD +
Sbjct: 1655 VLLEELEALKQLSLAGREKL---CCELRNSSTQTQNGNENQGEVEEQTFK--EKELDRKP 1709
Query: 422 EDKRKVLLELSR---EKAQNEDLKL 443
ED +L R +KA N LK+
Sbjct: 1710 EDVPPEILSNERYALQKANNRLLKI 1734
Score = 37.7 bits (86), Expect = 0.071
Identities = 73/349 (20%), Positives = 143/349 (40%), Gaps = 39/349 (11%)
Query: 230 NTMQVEEPPKSPEKMWPKDENFEQ--RSSLECAQKAAELRASIK-EKVELIRLKKLLHER 286
N E KS E W ++ + RS ++ +L+ S++ +K ++L LL ++
Sbjct: 3207 NDTLASEQKKSRELQWALEKEKAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQQ 3266
Query: 287 NASLVMTKAQLTEVQEAYETLLQKNQGI---LSAAHEALLKQVNELRAELKEESKKAVSL 343
L ++ ++ + Y+ L + QG L E+ ++ E+ + L E + L
Sbjct: 3267 KQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLESEKVRIREMSSTLDRERELHAQL 3326
Query: 344 KS-----QLEDVSILQMTLKEFQERVEDLEKER-KLLNDNYDKLLESMLDSSD------- 390
+S Q + LKE Q+++E+ +LLN+ L+S+
Sbjct: 3327 QSSDGTGQSRPPLPSEDLLKELQKQLEEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQV 3386
Query: 391 ------SSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLE 444
+ + + + +LQ +V LQ Q LE+KR+ + +L E + + + E
Sbjct: 3387 HRKTLQTEQEANTEGQKKMHELQSKVEDLQRQ----LEEKRQQVYKLDLEGQRLQGIMQE 3442
Query: 445 VTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQV 504
KQE+E + + +EP T ++ + T+ + K + E K S
Sbjct: 3443 F------QKQELEREEKRESRRILYQNLNEPTTW-SLTSDRTRNWVLQQKIEGETKESNY 3495
Query: 505 LNELQVSHAET--TLELEKTRDML-ILQRKINVCYQEELEAMMTKADND 550
++++ T ELE R L + K+ V Q+ E + + +D
Sbjct: 3496 AKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFETADD 3544
Score = 33.1 bits (74), Expect = 1.8
Identities = 67/314 (21%), Positives = 131/314 (41%), Gaps = 53/314 (16%)
Query: 299 EVQEAYETLLQKNQGILSAAHEALLK---------------QVNELRAELKEESKKAVSL 343
E + A ++ +K +G+L A H ++ + ++ EE K ++
Sbjct: 2931 ESESATDSFPKKIKGLLRAVHNEGMQVLSLTESPYSDGEDHSIQQVSEPWLEERKAYINT 2990
Query: 344 KSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLL---ESMLDSSDSSSQPHWSNE 400
S L+D+ I +M L+ E V D + + +D +LL + + S + E
Sbjct: 2991 ISSLKDL-ITKMQLQREAE-VYDSSQSHESFSDWRGELLLALQQVFLEERSVLLAAFRTE 3048
Query: 401 LIA--------------EQLQQQVSQLQDQLDA-ELEDKRKVLLELSREKAQNEDLKLEV 445
L A +++Q+Q + Q ++ + D+R +L E+ AQ K+ +
Sbjct: 3049 LTALGTTDAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITL 3108
Query: 446 TNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVL 505
+ K ELL+ I Q + E + +++ E E + E+ ++++
Sbjct: 3109 KREQESEKPSQELLE--YNIQQKQSQMLEMQVELSSMKDRA-TELQEQLSSEKMVVAELK 3165
Query: 506 NELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLL 565
+EL A+T LELE T L Q K + +ELEA + +D +++ L L
Sbjct: 3166 SEL----AQTKLELETT---LKAQHK----HLKELEAFRLEV----KDKTDEVHLLNDTL 3210
Query: 566 DLKNNRIKQLEGIL 579
+ + ++L+ L
Sbjct: 3211 ASEQKKSRELQWAL 3224
Score = 32.0 bits (71), Expect = 3.9
Identities = 37/186 (19%), Positives = 82/186 (44%), Gaps = 25/186 (13%)
Query: 333 LKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSS 392
L +E + +S+ SQ+ ++ + + K ++DLEK + L + + LES++ S
Sbjct: 1297 LPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTK--LEEQVQE-LESLISS---- 1349
Query: 393 SQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKH 452
LQQQ+ + + +AE+ +K L +S L V +++
Sbjct: 1350 -------------LQQQLKETEQNYEAEIHCLQKRLQAVSESTVPP---SLPVDSVVITE 1393
Query: 453 KQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQE--EKKLSQVLNELQV 510
+ + + + D E + V +E ++ E + QE E+++++V+ + +
Sbjct: 1394 SDAQRTMYPGSCVKKNIDGTIEFSGEFGVKEETNIVKLLEKQYQEQLEEEVAKVIVSMSI 1453
Query: 511 SHAETT 516
+ A+ T
Sbjct: 1454 AFAQQT 1459
Score = 31.6 bits (70), Expect = 5.1
Identities = 50/225 (22%), Positives = 97/225 (43%), Gaps = 30/225 (13%)
Query: 264 AELRASIKEKVELIRLKKLLH----ERNASLVMTKAQLTEVQEAYETLLQKNQ--GILSA 317
AE KEK +L+ L+KLL ++ Q EV + L N+ G +
Sbjct: 2632 AEKNVLEKEK-KLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNE 2690
Query: 318 AHEALLKQVNELRAELKEESKKAVSLKSQL-----------EDVSILQMTLKEFQERVED 366
EAL + +AEL +KA L+ +L +D+S ++ L E +E++
Sbjct: 2691 L-EALRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSI 2749
Query: 367 LEKERK----------LLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQ 416
LEKE + + KL +S+ +D + + SN+ ++ Q+ Q
Sbjct: 2750 LEKEDETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQ 2809
Query: 417 LDAELEDKRKVLLELSREKAQNEDL-KLEVTNILQKHKQEVELLQ 460
+ E+ +++ + + + + ++L E+ ++ +H E E L+
Sbjct: 2810 SECSSEEVTEIISQFTEKIEKMQELHAAEILDMESRHISETETLK 2854
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 65.5 bits (158), Expect = 3e-10
Identities = 92/419 (21%), Positives = 180/419 (42%), Gaps = 42/419 (10%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
EQ S L Q + +R ++ K E+ + + L L + AQ TE Q+ E ++
Sbjct: 135 EQGSGLSMDQHS-NIRDLLRFKEEVTKERDQLLSEVVKLRESLAQTTEQQQETERSKEEA 193
Query: 312 QGILSAAHEALLKQVNELRAELKEESKKAVSLK-------SQLEDVSILQMTLKEFQERV 364
+ +S + + ++ NE E +++ K LK S+ ++ LQ +++ +E +
Sbjct: 194 EHAISQFQQEIQQRQNEASREFRKKEKLEKELKQIQADMDSRQTEIKALQQYVQKSKEEL 253
Query: 365 EDLE---KERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAEL 421
+ LE KE+K+LN+ K LE + Q + + L+ EQL Q+ Q +L A+
Sbjct: 254 QKLEQQLKEQKILNERAAKELEQFQMRNAKLQQENEQHSLVCEQLSQENQQKALELKAKE 313
Query: 422 EDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQP---PDRQSEPATH 478
E+ ++ L++ + E + ++ + Q+ E+ Q+ T+ +R+ E +
Sbjct: 314 EEVHQMRLDIGKLNKIREQIHKKLHH---TEDQKAEVEQHKETLKNQIVGLEREVEASKK 370
Query: 479 PAVLQENTQIEPSEPKNQEEKKLSQVLNELQV--------SHAETTL--ELEKTRDMLIL 528
A L E ++ K + + +N Q A+ L E++ +D
Sbjct: 371 QAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQK 430
Query: 529 QRKINVCYQEELEAMMTKADNDNRDHKEKLE----RLTRLLDLKNN------RIKQLEGI 578
QRKI ++E + + +A + + +E R T++ D + ++KQ + +
Sbjct: 431 QRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNL 490
Query: 579 ---LRSHDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLLHQGENLFELHIHQ 634
+RS S+ L + + L+ + DE K DIS L +LH+ Q
Sbjct: 491 YEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDISAKESA--LVKLHLEQ 547
Score = 51.6 bits (122), Expect = 5e-06
Identities = 64/275 (23%), Positives = 115/275 (41%), Gaps = 46/275 (16%)
Query: 322 LLKQVNELRAELKEESKK-AVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDK 380
L+ + EL AE+ S K A +LK +D + + KE +EK K+++ YDK
Sbjct: 60 LMAKCRELNAEIVVNSAKVATALKLSQDDQTTIASLKKE-------IEKAWKMVDSAYDK 112
Query: 381 L----------------LESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDK 424
L +++ S SN + +++V++ +DQL +E+
Sbjct: 113 EQKAKETILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVTKERDQLLSEVVKL 172
Query: 425 RKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQE 484
R+ L + + ++ + E K E + + + +QE++ QN A+ + E +E
Sbjct: 173 RESLAQTTEQQQETERSKEEAEHAISQFQQEIQQRQNEASREFRKKEKLE--------KE 224
Query: 485 NTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMM 544
QI+ Q E + LQ ++ EL+K L Q+ +N +ELE
Sbjct: 225 LKQIQADMDSRQTE------IKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELEQFQ 278
Query: 545 ---TKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
K +N H E+L+ + N+ K LE
Sbjct: 279 MRNAKLQQENEQHSLVCEQLS-----QENQQKALE 308
Score = 51.6 bits (122), Expect = 5e-06
Identities = 90/397 (22%), Positives = 177/397 (44%), Gaps = 70/397 (17%)
Query: 253 QRSSLECAQKAAELRASIKE----KVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLL 308
++ S E QKA EL+A +E ++++ +L K+ + + L T+ Q EV++ ETL
Sbjct: 296 EQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKLHHTEDQKAEVEQHKETL- 354
Query: 309 QKNQGI-LSAAHEALLKQ-------VNELRAE---LKEESKKAVSLKSQLEDVSILQMTL 357
KNQ + L EA KQ ++EL E L + KAV+ + D+ L
Sbjct: 355 -KNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLKAVNATQKQTDLVKLHEQA 413
Query: 358 K-----EFQERVEDLEKERKLL--------------NDNYDKLLESMLDSSDSSSQPHWS 398
K E Q ++ +K+RK++ +D K+L +M D +Q
Sbjct: 414 KRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIKVRETQIFDY 473
Query: 399 NELIAE---QLQQQVS--------------QLQDQLDAELEDKRKVLLELSREKAQNEDL 441
+ IAE +L+QQ + L + D + KRK+ + + + ED+
Sbjct: 474 RKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVDELKEDI 533
Query: 442 KLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKL 501
+ + +++ H ++ + + T+ + + A L+ IE E EE+KL
Sbjct: 534 SAKESALVKLHLEQQRIEKEKETLKAELQKLRQQA-----LETKHFIEKQE---AEERKL 585
Query: 502 SQVLNELQVSHAETTLELEKT---RDML---ILQRKINVC-YQEELEAMMTKADNDNRDH 554
+++ E EL++ RD+L +++R + E+++ + + +
Sbjct: 586 LRIIAEADGERLRQKKELDQVISERDILGSQLVRRNDELALLYEKIKIQQSVLNKGESQY 645
Query: 555 KEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLK 591
++LE + R+L L+ ++++ +GIL + + E+L+
Sbjct: 646 NQRLEDM-RILRLEIKKLRREKGIL-ARSMANVEELR 680
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 65.1 bits (157), Expect = 4e-10
Identities = 88/396 (22%), Positives = 165/396 (41%), Gaps = 48/396 (12%)
Query: 239 KSPEKMWPKDENFE-QRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQL 297
+S E+ P++ N QR ++ A+E+ + ++L++L + QL
Sbjct: 50 ESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQHEQL 109
Query: 298 TEVQEAYETLLQKNQG-------ILSAAHEA-----------LLKQVNELRAELKEESKK 339
+ Q E Q Q + H++ L+ Q +L+ + +E ++
Sbjct: 110 QQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQR 169
Query: 340 AVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSN 399
+ QL+ + + + QE+++ +E++LL ++L + L Q
Sbjct: 170 LQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ---- 225
Query: 400 ELIAEQLQQQVSQLQDQLDAELEDKRKVLLE--LSREKAQNEDLKLEVTNILQKHKQEVE 457
+Q QQQ QLQ Q L ++ L + L +++AQ + LE Q Q+
Sbjct: 226 ----QQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQ---QAQLQQQL 278
Query: 458 LLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTL 517
LLQ + Q +Q + Q+ Q P EP+ +EE +L EL +
Sbjct: 279 LLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVEL-----ELMPVDLGSEQ 333
Query: 518 ELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEG 577
ELE+ R L Q+++ Q+E + K +E+L++L + L+ + +++Q E
Sbjct: 334 ELEQQRQELERQQELE--RQQEQRQLQLKL-------QEELQQLEQQLEQQQQQLEQQEV 384
Query: 578 ILRSHDLPTSEQLKDVAYGTRPL--SLCLETLPAHG 611
L + Q ++V P+ L LE +PA G
Sbjct: 385 QLELTPVELGAQQQEVQLELTPVQPELQLELVPAAG 420
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 64.7 bits (156), Expect = 5e-10
Identities = 98/393 (24%), Positives = 158/393 (40%), Gaps = 77/393 (19%)
Query: 247 KDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQ--EAY 304
K E + R LE A+K ++K L E+NA + E+Q E
Sbjct: 741 KSEMKKLRQQLEAAEK---------------QIKHLEIEKNAESSKASSITRELQGRELK 785
Query: 305 ETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSL-KSQLEDVSILQMTLKEFQER 363
T LQ+N +S E L K++ L+ + E S++AVS+ +S E V+ L ++F
Sbjct: 786 LTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNML 845
Query: 364 VEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELI--AEQLQQQVSQLQDQLDAEL 421
DLEK R+ L D +E+ D + +LI E+L+ ++++
Sbjct: 846 SSDLEKLRENLAD-----MEAKFREKDEREE-----QLIKAKEKLENDIAEIMKMSGDNS 895
Query: 422 EDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNA---ATISQPPDRQSEPATH 478
K+ EL ++ E+L+L++T K + LQ + T+ +Q H
Sbjct: 896 SQLTKMNDELRLKERDVEELQLKLT----KANENASFLQKSIEDMTVKAEQSQQEAAKKH 951
Query: 479 PAVLQE--------NTQIEPSEPKNQEEK-KLSQVLNELQVSHAETTLELEK----TRDM 525
+E ++E S + QE K + + +E + H E L+K T D
Sbjct: 952 EEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK 1011
Query: 526 LILQRKINVCYQEELEAMMTKADNDNRDH-------------KEKLERLTRLLD------ 566
L R+ N +ELE + +AD KEK E L L D
Sbjct: 1012 LKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA 1071
Query: 567 --------LKNNRIKQLEGILRSHDLPTSEQLK 591
LK N +K +E + +S +L T E K
Sbjct: 1072 KLQNELDTLKENNLKNVEELNKSKELLTVENQK 1104
Score = 57.8 bits (138), Expect = 7e-08
Identities = 92/413 (22%), Positives = 172/413 (41%), Gaps = 68/413 (16%)
Query: 179 EHATNENRGEVASKPSELVSG--SNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEE 236
EHA EN +A S+L + S+ +S +K +G + T + E
Sbjct: 564 EHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLG-----------TETAEFAE 612
Query: 237 PPKSPEKM----WPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVM 292
EKM + EN + + E A A E+ A +L K++ E+ SL
Sbjct: 613 LKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEAL------RAKLMKVIKEKENSLEA 666
Query: 293 TKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSI 352
+++L + ++ + ++ L A E +K++ L+A+ E++K + SQL
Sbjct: 667 IRSKLDKAEDQHLVEMEDTLNKLQEA-EIKVKELEVLQAKCNEQTKVIDNFTSQL----- 720
Query: 353 LQMTLKEFQERVEDLEKERKLLNDNYDKL------------------LESMLDSSDSSS- 393
K +E++ DL+ RK ++ ++ +E +SS +SS
Sbjct: 721 -----KATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSI 775
Query: 394 -QPHWSNELIAEQLQQ---QVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNIL 449
+ EL LQ+ +VSQ+++ L+ EL+ ++ E S E + E N L
Sbjct: 776 TRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKL 835
Query: 450 QKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQ 509
+ +++ +L S + A A +E + E K +E KL + E+
Sbjct: 836 HQKEEQFNMLS-----SDLEKLRENLADMEAKFREKDEREEQLIKAKE--KLENDIAEIM 888
Query: 510 VSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLT 562
+ + +L K D L L+ + EEL+ +TKA+ + ++ +E +T
Sbjct: 889 KMSGDNSSQLTKMNDELRLKER----DVEELQLKLTKANENASFLQKSIEDMT 937
Score = 56.6 bits (135), Expect = 1e-07
Identities = 75/349 (21%), Positives = 149/349 (42%), Gaps = 40/349 (11%)
Query: 266 LRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETL-------------LQKNQ 312
L+ ++KEK + +++LL ER+ + V E + L L+
Sbjct: 353 LQEALKEKQQ--HIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKM 410
Query: 313 GILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSI----LQMTLKEFQERVEDLE 368
L EA ++ EL +L+EE +K L+ ++E+ SI L++ + R+ +LE
Sbjct: 411 DQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELE 470
Query: 369 KERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVL 428
K+ L +L L+S+ + S L+ Q++S LQ++L+ D ++ +
Sbjct: 471 KDLALRVQEVAEL-RRRLESNKPAGDVDMSLSLL-----QEISSLQEKLEVTRTDHQREI 524
Query: 429 LELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQI 488
L E+ H++E++ L A T + +S + +EN+ +
Sbjct: 525 TSLKEHFGAREET----------HQKEIKALYTA-TEKLSKENESLKSKLEHANKENSDV 573
Query: 489 EPSEPKNQEEKKLS--QVLNELQVSHAETT-LELEKTRDMLILQRKINVCYQEELEAMMT 545
E S Q + EL+VS ++ E + ++ K+ + YQ E+E +
Sbjct: 574 IALWKSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQN 633
Query: 546 KADNDNRDHKEKLERL-TRLLDLKNNRIKQLEGILRSHDLPTSEQLKDV 593
+ D++ H +++E L +L+ + + LE I D + L ++
Sbjct: 634 QQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEM 682
Score = 48.1 bits (113), Expect = 5e-05
Identities = 76/361 (21%), Positives = 162/361 (44%), Gaps = 43/361 (11%)
Query: 235 EEPPKSPEKMWPKDENFEQRSSLECAQ-KAAELRASIKEKVELIRLKKLLHERNASLVMT 293
EE K E+ E + S +C + KA RA+ + K + +++L +L+ T
Sbjct: 952 EEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKT---KHEEILQNLQKTLLDT 1008
Query: 294 KAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAEL-----KEESKKAVSLKSQLE 348
+ +L +E LLQ+ + + A +A Q E ++ KE+++ SL+ +
Sbjct: 1009 EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQ 1068
Query: 349 DVSILQMTLKEFQER----VEDLEKERKLLN------DNYDKLLESMLDSSDSSSQPHWS 398
+ LQ L +E VE+L K ++LL + + K +E++ ++ SQ +
Sbjct: 1069 TNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSA 1128
Query: 399 NELIAEQLQQQVSQLQDQLDA--ELEDKRKVL----LELSREK------AQNEDLKLE-- 444
+ +L +++ + +D++ + +LE++R VL LE+ + + A E L+
Sbjct: 1129 LQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKS 1188
Query: 445 --VTNILQKHKQ-EVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKL 501
+T+ L K E+E L+N T+ + + ++ E+ +++ E +L
Sbjct: 1189 ISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQL 1248
Query: 502 SQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
+ N+ Q+S + + + D + +I+ L +++ N+D K K+E +
Sbjct: 1249 KE--NKRQLSSSSGNTDTQADEDERAQESQIDF-----LNSVIVDLQRKNQDLKMKVEMM 1301
Query: 562 T 562
+
Sbjct: 1302 S 1302
>gi|4506751 restin isoform a [Homo sapiens]
Length = 1427
Score = 64.7 bits (156), Expect = 5e-10
Identities = 98/393 (24%), Positives = 158/393 (40%), Gaps = 77/393 (19%)
Query: 247 KDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQ--EAY 304
K E + R LE A+K ++K L E+NA + E+Q E
Sbjct: 776 KSEMKKLRQQLEAAEK---------------QIKHLEIEKNAESSKASSITRELQGRELK 820
Query: 305 ETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSL-KSQLEDVSILQMTLKEFQER 363
T LQ+N +S E L K++ L+ + E S++AVS+ +S E V+ L ++F
Sbjct: 821 LTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNML 880
Query: 364 VEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELI--AEQLQQQVSQLQDQLDAEL 421
DLEK R+ L D +E+ D + +LI E+L+ ++++
Sbjct: 881 SSDLEKLRENLAD-----MEAKFREKDEREE-----QLIKAKEKLENDIAEIMKMSGDNS 930
Query: 422 EDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNA---ATISQPPDRQSEPATH 478
K+ EL ++ E+L+L++T K + LQ + T+ +Q H
Sbjct: 931 SQLTKMNDELRLKERDVEELQLKLT----KANENASFLQKSIEDMTVKAEQSQQEAAKKH 986
Query: 479 PAVLQE--------NTQIEPSEPKNQEEK-KLSQVLNELQVSHAETTLELEK----TRDM 525
+E ++E S + QE K + + +E + H E L+K T D
Sbjct: 987 EEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDK 1046
Query: 526 LILQRKINVCYQEELEAMMTKADNDNRDH-------------KEKLERLTRLLD------ 566
L R+ N +ELE + +AD KEK E L L D
Sbjct: 1047 LKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNA 1106
Query: 567 --------LKNNRIKQLEGILRSHDLPTSEQLK 591
LK N +K +E + +S +L T E K
Sbjct: 1107 KLQNELDTLKENNLKNVEELNKSKELLTVENQK 1139
Score = 57.8 bits (138), Expect = 7e-08
Identities = 92/413 (22%), Positives = 172/413 (41%), Gaps = 68/413 (16%)
Query: 179 EHATNENRGEVASKPSELVSG--SNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQVEE 236
EHA EN +A S+L + S+ +S +K +G + T + E
Sbjct: 599 EHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGLG-----------TETAEFAE 647
Query: 237 PPKSPEKM----WPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVM 292
EKM + EN + + E A A E+ A +L K++ E+ SL
Sbjct: 648 LKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEAL------RAKLMKVIKEKENSLEA 701
Query: 293 TKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSI 352
+++L + ++ + ++ L A E +K++ L+A+ E++K + SQL
Sbjct: 702 IRSKLDKAEDQHLVEMEDTLNKLQEA-EIKVKELEVLQAKCNEQTKVIDNFTSQL----- 755
Query: 353 LQMTLKEFQERVEDLEKERKLLNDNYDKL------------------LESMLDSSDSSS- 393
K +E++ DL+ RK ++ ++ +E +SS +SS
Sbjct: 756 -----KATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSI 810
Query: 394 -QPHWSNELIAEQLQQ---QVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNIL 449
+ EL LQ+ +VSQ+++ L+ EL+ ++ E S E + E N L
Sbjct: 811 TRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKL 870
Query: 450 QKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQ 509
+ +++ +L S + A A +E + E K +E KL + E+
Sbjct: 871 HQKEEQFNMLS-----SDLEKLRENLADMEAKFREKDEREEQLIKAKE--KLENDIAEIM 923
Query: 510 VSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLT 562
+ + +L K D L L+ + EEL+ +TKA+ + ++ +E +T
Sbjct: 924 KMSGDNSSQLTKMNDELRLKER----DVEELQLKLTKANENASFLQKSIEDMT 972
Score = 54.7 bits (130), Expect = 6e-07
Identities = 77/345 (22%), Positives = 147/345 (42%), Gaps = 39/345 (11%)
Query: 257 LECAQKAAELRASI----KEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQ 312
LE K +LR + +EKVEL L +L E+ K + + + E++ +
Sbjct: 404 LELEAKMDQLRTMVEAADREKVEL--LNQLEEEKR------KVEDLQFRVEEESI---TK 452
Query: 313 GILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERK 372
G L + ++ EL L E KA L+ +LED + ++ K R+ +LEK+
Sbjct: 453 GDLETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKS---RIMELEKDLA 509
Query: 373 LLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELS 432
L +L L+S+ + S L+ Q++S LQ++L+ D ++ + L
Sbjct: 510 LRVQEVAEL-RRRLESNKPAGDVDMSLSLL-----QEISSLQEKLEVTRTDHQREITSLK 563
Query: 433 REKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSE 492
E+ H++E++ L A T + +S + +EN+ +
Sbjct: 564 EHFGAREET----------HQKEIKALYTA-TEKLSKENESLKSKLEHANKENSDVIALW 612
Query: 493 PKNQEEKKLS--QVLNELQVSHAETT-LELEKTRDMLILQRKINVCYQEELEAMMTKADN 549
E S Q + EL+VS ++ E + ++ K+ + YQ E+E + + D+
Sbjct: 613 KSKLETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDS 672
Query: 550 DNRDHKEKLERL-TRLLDLKNNRIKQLEGILRSHDLPTSEQLKDV 593
+ H +++E L +L+ + + LE I D + L ++
Sbjct: 673 ERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEM 717
Score = 48.1 bits (113), Expect = 5e-05
Identities = 76/361 (21%), Positives = 162/361 (44%), Gaps = 43/361 (11%)
Query: 235 EEPPKSPEKMWPKDENFEQRSSLECAQ-KAAELRASIKEKVELIRLKKLLHERNASLVMT 293
EE K E+ E + S +C + KA RA+ + K + +++L +L+ T
Sbjct: 987 EEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKT---KHEEILQNLQKTLLDT 1043
Query: 294 KAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAEL-----KEESKKAVSLKSQLE 348
+ +L +E LLQ+ + + A +A Q E ++ KE+++ SL+ +
Sbjct: 1044 EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQ 1103
Query: 349 DVSILQMTLKEFQER----VEDLEKERKLLN------DNYDKLLESMLDSSDSSSQPHWS 398
+ LQ L +E VE+L K ++LL + + K +E++ ++ SQ +
Sbjct: 1104 TNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSA 1163
Query: 399 NELIAEQLQQQVSQLQDQLDA--ELEDKRKVL----LELSREK------AQNEDLKLE-- 444
+ +L +++ + +D++ + +LE++R VL LE+ + + A E L+
Sbjct: 1164 LQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKS 1223
Query: 445 --VTNILQKHKQ-EVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKL 501
+T+ L K E+E L+N T+ + + ++ E+ +++ E +L
Sbjct: 1224 ISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQL 1283
Query: 502 SQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
+ N+ Q+S + + + D + +I+ L +++ N+D K K+E +
Sbjct: 1284 KE--NKRQLSSSSGNTDTQADEDERAQESQIDF-----LNSVIVDLQRKNQDLKMKVEMM 1336
Query: 562 T 562
+
Sbjct: 1337 S 1337
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 64.7 bits (156), Expect = 5e-10
Identities = 61/245 (24%), Positives = 113/245 (46%), Gaps = 32/245 (13%)
Query: 266 LRASIKEKVELIR--LKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALL 323
++ S+K ++EL L+K +HE+ +L+ + QL EV+ + QK QG E L
Sbjct: 356 VQVSMKHEIELAMKLLEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQG-----SEDGL 410
Query: 324 KQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLE 383
K+ NE+ A L+E++ K + QLE +R++ EK + D +K L+
Sbjct: 411 KEKNEIIARLEEKTNKITAAMRQLE-------------QRLQQAEKAQMEAEDEDEKYLQ 457
Query: 384 SMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKL 443
L SDS + Q ++Q+ QL+ L E E ++ + +L +EK L+
Sbjct: 458 ECLSKSDSLQKQ-------ISQKEKQLVQLETDLKIEKEWRQTLQEDLQKEKDALSHLRN 510
Query: 444 EVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQ 503
E I+ K+ + L + + Q + A+ + ++ S+ K ++ K+ ++
Sbjct: 511 ETQQIISLKKEFLNLQDENQQLKKIYHEQEQ-----ALQELGNKLSESKLKIEDIKEANK 565
Query: 504 VLNEL 508
L L
Sbjct: 566 ALQGL 570
Score = 37.7 bits (86), Expect = 0.071
Identities = 49/248 (19%), Positives = 97/248 (39%), Gaps = 33/248 (13%)
Query: 353 LQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQ 412
L T+ RV+ LEK L + +++ + + Q N+LI + QQ +
Sbjct: 251 LNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEENHQLRSENKLILMKTQQHLEV 310
Query: 413 LQDQLDAELEDKR-------KVLLELSREKAQNEDLKLEVTN-----ILQKHKQEVELLQ 460
+ ++ EL+ + ++ E R+ L+ +V N + KH+ E+ +
Sbjct: 311 TKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQDVENELAVQVSMKHEIELAMKL 370
Query: 461 NAATISQPPD-----RQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAET 515
I + D RQ ++ +++ SE +E+ ++ L
Sbjct: 371 LEKDIHEKQDTLIGLRQQLEEVKAINIEMYQKLQGSEDGLKEKNEIIARLE--------- 421
Query: 516 TLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKE---KLERLTRLLDLKNNRI 572
EKT + R++ Q+ +A M D D + +E K + L + + K ++
Sbjct: 422 ----EKTNKITAAMRQLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQL 477
Query: 573 KQLEGILR 580
QLE L+
Sbjct: 478 VQLETDLK 485
Score = 33.1 bits (74), Expect = 1.8
Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 11/144 (7%)
Query: 233 QVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEK-VELIRLKKLLHERNASLV 291
Q+E+ + EK + E+ +++ EC K+ L+ I +K +L++L+ L
Sbjct: 433 QLEQRLQQAEKAQMEAEDEDEKYLQECLSKSDSLQKQISQKEKQLVQLETDLKIEKEWRQ 492
Query: 292 MTKAQLTEVQEAYETLLQKNQGILSAAHEAL-LKQVNELRAELKEESKKAVSLKSQLEDV 350
+ L + ++A L + Q I+S E L L+ N+ ++ E ++A +
Sbjct: 493 TLQEDLQKEKDALSHLRNETQQIISLKKEFLNLQDENQQLKKIYHEQEQA---------L 543
Query: 351 SILQMTLKEFQERVEDLEKERKLL 374
L L E + ++ED+++ K L
Sbjct: 544 QELGNKLSESKLKIEDIKEANKAL 567
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 64.3 bits (155), Expect = 7e-10
Identities = 82/375 (21%), Positives = 159/375 (42%), Gaps = 56/375 (14%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
++ S ++C + + LR +EKV L+K L E + ++ L E++ A E +N
Sbjct: 819 QEESVVQCEELKSLLRDYEQEKV---LLRKELEEIQSEKEALQSDLLEMKNANEKTRLEN 875
Query: 312 QGILSAAHEA----------------LLKQVNELRA-----ELKEESKKAVSLKSQLEDV 350
Q +L E +K+ L+ EL++ + + LK L
Sbjct: 876 QNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKS 935
Query: 351 SILQ----MTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQL 406
++ ++KE +E++E+LEKE K + +K+ + + + + E+L
Sbjct: 936 PSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEEL 995
Query: 407 QQQVSQLQDQLDAELED----------------KRKVLLELSREKAQNEDLKLE-VTNIL 449
+ S+ +DQL A + D K+ L++ +E+A N + ++E +T L
Sbjct: 996 ESLRSE-KDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQL 1054
Query: 450 QKHKQEVELL--QNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNE 507
+ + E + N +++ QS + E + + K E +KL + +
Sbjct: 1055 RNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQK--EQ 1112
Query: 508 LQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADN------DNRDHKEKLERL 561
HA T ELE+ + L ++K +ELE + A + D++ ++ L
Sbjct: 1113 KIKEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKEL 1172
Query: 562 TRLLDLKNNRIKQLE 576
+ L KNN+I+ LE
Sbjct: 1173 NQKLTNKNNKIEDLE 1187
Score = 59.3 bits (142), Expect = 2e-08
Identities = 98/408 (24%), Positives = 166/408 (40%), Gaps = 67/408 (16%)
Query: 239 KSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLT 298
K+ + ++ E+ S + ++ ++ E+++ + L+K E+ L + K +
Sbjct: 43 KAKSRCTELEKEIEELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQC-LSLKKENIK 101
Query: 299 EVQEAYETLLQKNQGI--LSAAHEALLKQV----NELRAELKEESKKAVSLKSQLEDVSI 352
QE +++ + L +H +K++ NEL A + S+ +L+ QLE+
Sbjct: 102 MKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMN 161
Query: 353 LQMTLKE---FQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQ 409
Q+ L E FQ E DN KL E + E I ++Q
Sbjct: 162 TQLELSEQLKFQNNSE----------DNVKKLQEEI--------------EKIRPGFEEQ 197
Query: 410 VSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPP 469
+ LQ QLDA ++K++ + +L N + N LQ+ ELLQ A
Sbjct: 198 ILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQE-----ELLQLKAI----- 247
Query: 470 DRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQ 529
Q E V + QIE S +++ E LNEL+ + + EK +Q
Sbjct: 248 -HQEE------VKELMCQIEASAKEHEAE---INKLNELKENLVKQCEASEKN-----IQ 292
Query: 530 RKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQ 589
+K C E L + A+ DN+ L+ T + + N ++K LE L+ + S
Sbjct: 293 KKYE-CELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHS-I 350
Query: 590 LKDVAYGTRPLSLCLETLPAHGDEDKVDISLLHQGENLFELHIHQAFL 637
LKD L L LE D + H+ E+L E I++ L
Sbjct: 351 LKDEVTYMNNLKLKLEM-----DAQHIKDEFFHEREDL-EFKINELLL 392
Score = 53.1 bits (126), Expect = 2e-06
Identities = 65/312 (20%), Positives = 148/312 (47%), Gaps = 51/312 (16%)
Query: 271 KEKVELIRLKKLLHERNASLVM---TKAQLTEVQEAYETLLQK--NQGILSAAHEALLKQ 325
K K+E + + L+ +++ K++ TE+++ E L K +G +AL ++
Sbjct: 19 KSKLETLPKEDLIKFAKKQMMLIQKAKSRCTELEKEIEELRSKPVTEGTGDII-KALTER 77
Query: 326 VNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESM 385
++ L E E ++ +SLK E++ + Q +++ ++ D KE + + NY K +E++
Sbjct: 78 LDALLLEKAETEQQCLSLKK--ENIKMKQ-EVEDSVTKMGDAHKELEQSHINYVKEIENL 134
Query: 386 LDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSRE-KAQNEDLKLE 444
NEL+A ++ + S+ + L +LE+ LELS + K QN
Sbjct: 135 ------------KNELMA--VRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNS---- 176
Query: 445 VTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQV 504
+ ++K ++E+E ++ P +L Q++ + + +E ++Q+
Sbjct: 177 -EDNVKKLQEEIEKIR--------------PGFEEQILYLQKQLDATTDEKKET--VTQL 219
Query: 505 LNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRL 564
N ++ + + ++ L+ ++ +QEE++ +M + + ++H+ ++ +L
Sbjct: 220 QNIIEANSQHYQKNINSLQEELL---QLKAIHQEEVKELMCQIEASAKEHEAEINKLN-- 274
Query: 565 LDLKNNRIKQLE 576
+LK N +KQ E
Sbjct: 275 -ELKENLVKQCE 285
Score = 53.1 bits (126), Expect = 2e-06
Identities = 83/363 (22%), Positives = 161/363 (44%), Gaps = 64/363 (17%)
Query: 252 EQRSSLECAQKAAEL---RASIKEKVELIR--LKKLLHERNASLVMTKAQLTEVQEAYET 306
E+R LE +K + + +++KV + L++ L E++ + + + +++
Sbjct: 620 EERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMK----- 674
Query: 307 LLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVED 366
+L +++ +LSA ++L ++ N+L +E K+ S+ SQ EDV + +E +
Sbjct: 675 VLSEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVIL--------KEHITQ 726
Query: 367 LEKERKLL---NDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELED 423
LEK+ +L+ DN +KLLE+ EQ+Q+ ++ QL L++
Sbjct: 727 LEKKLQLMVEEQDNLNKLLEN-------------------EQVQKLF--VKTQLYGFLKE 765
Query: 424 KRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELL--QNAATISQPPDRQSEPATHPAV 481
+ E S EK +V N+LQ + + + + Q ++ E
Sbjct: 766 MGSEVSEDSEEK--------DVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKC 817
Query: 482 LQENTQIEPSEPKN------QEEKKLSQVLNELQVSH---AETTLELEKTRDMLILQRKI 532
LQE + ++ E K+ QE+ L + L E+Q LE++ + L+ +
Sbjct: 818 LQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQN 877
Query: 533 NVCYQEELEAMMTKADNDNRDHK---EKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQ 589
+ EE+ +K++ N K ++ E L LL+ K R ++ E IL L S
Sbjct: 878 LLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLAKSPS 937
Query: 590 LKD 592
+K+
Sbjct: 938 VKN 940
Score = 53.1 bits (126), Expect = 2e-06
Identities = 78/354 (22%), Positives = 147/354 (41%), Gaps = 52/354 (14%)
Query: 253 QRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQ 312
+ S+L+C ++ + L KLL + + KA + + EA + LQK Q
Sbjct: 1055 RNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEK--LQKEQ 1112
Query: 313 GILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDV-------SILQMTLKEFQE--- 362
I H + ++ EL+ +L++E K+ +LE V +++ M + +++
Sbjct: 1113 KIKE--HATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMK 1170
Query: 363 -----------RVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVS 411
++EDLE+E K+ + L E + S Q N I + L +
Sbjct: 1171 ELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKK 1230
Query: 412 QLQDQLDAE-----LEDKRKVLLELSREKAQNEDLKL-EVTN-----------ILQKHKQ 454
+L D AE L+ K LE S+++ + ++L E+T+ ++H++
Sbjct: 1231 ELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQR 1290
Query: 455 EVELLQNAATISQPPDR--QSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSH 512
+ Q T Q R ++E AT + + + K Q+ K +SQ +
Sbjct: 1291 TLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQ-------AE 1343
Query: 513 AETTLELEKTRDMLILQRKINV-CYQEELEAMMTKADNDNRDHKEKLERLTRLL 565
E + + +MLI Q KI + Q L+ +++ +H LER ++L
Sbjct: 1344 TEGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKML 1397
Score = 46.6 bits (109), Expect = 2e-04
Identities = 71/338 (21%), Positives = 141/338 (41%), Gaps = 64/338 (18%)
Query: 247 KDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYET 306
KDE F +R LE K+ + L K E+ + K++L + + +
Sbjct: 373 KDEFFHEREDLEF-------------KINELLLAK--EEQGCVIEKLKSELAGLNKQFCY 417
Query: 307 LLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVED 366
++++ + + E K+++EL +S+K + L ++ +E+ E+
Sbjct: 418 TVEQHNREVQSLKEQHQKEISELNETFLSDSEK---------EKLTLMFEIQGLKEQCEN 468
Query: 367 LEKERKLLNDNYDKLLESM----LDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
L++E++ NY+ L E M + +S+ + E + +Q V +LQ +L
Sbjct: 469 LQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFT 528
Query: 423 DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVL 482
+K +L ++R + +NE L L ++ + + ++ LQ + ++
Sbjct: 529 EKDALLETVNRLQGENEKL-LSQQELVPELENTIKNLQ-----------EKNGVYLLSLS 576
Query: 483 QENTQIEPSEPK-NQEEKKLSQVLNELQVSHAE-------------TTLELEKTRDMLI- 527
Q +T ++ E K N ++ +N+L+ SH E LEL K + I
Sbjct: 577 QRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGKKVEQTIQ 636
Query: 528 ----LQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
L++K+N E + K ND +KLE+L
Sbjct: 637 YNSELEQKVNELTGGLEETLKEKDQND-----QKLEKL 669
Score = 38.9 bits (89), Expect = 0.032
Identities = 69/348 (19%), Positives = 152/348 (43%), Gaps = 37/348 (10%)
Query: 253 QRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQ 312
Q++ ++ +L+A +E+V K+L+ + AS +A++ ++ E E L+++ +
Sbjct: 231 QKNINSLQEELLQLKAIHQEEV-----KELMCQIEASAKEHEAEINKLNELKENLVKQCE 285
Query: 313 GILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKE--FQERVEDLEKE 370
A E +++ E E ++ + +Q+ + + + T E E+V+ LE
Sbjct: 286 -----ASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDT 340
Query: 371 RKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLE 430
K L + L + + ++ + + I ++ + L+ +++ L K +
Sbjct: 341 LKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCV 400
Query: 431 LSREKAQNEDLKLEVTNILQKHKQEVELL--QNAATISQ-----PPDRQSEPATHPAVLQ 483
+ + K++ L + +++H +EV+ L Q+ IS+ D + E T +Q
Sbjct: 401 IEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQ 460
Query: 484 ------ENTQIEPSEPKNQEEKKLSQVLNELQVSHAET---------TLELEKTRDMLIL 528
EN Q E E E L +++ LQ E+ +++ ++ D+ L
Sbjct: 461 GLKEQCENLQQEKQEAILNYE-SLREIMEILQTELGESAGKISQEFESMKQQQASDVHEL 519
Query: 529 QRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
Q+K+ + E+ +A++ + N + EKL L+ N IK L+
Sbjct: 520 QQKLRTAFTEK-DALL-ETVNRLQGENEKLLSQQELVPELENTIKNLQ 565
Score = 37.0 bits (84), Expect = 0.12
Identities = 59/298 (19%), Positives = 118/298 (39%), Gaps = 22/298 (7%)
Query: 283 LHERNASLVMTKAQLTEVQEAYETLL------QKNQGILSAAHEALLKQ-------VNEL 329
L E + +A +T E+Y+ + QKN+ + A E ++ +++L
Sbjct: 1302 LQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL 1361
Query: 330 RAELKEESKKAVSLKSQLEDVSILQMTLKEFQERV--EDLEKERKLLNDNYDKLLESMLD 387
+ +L++ S+L+ + TL E ++ E + KE +L E+M+
Sbjct: 1362 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMM 1421
Query: 388 SSDSS---SQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLE 444
S+ + SQ NE++ + QV LQ++ +E ++ +LS+ +AQ LK E
Sbjct: 1422 KSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQ---QLSKMEAQLFQLKNE 1478
Query: 445 -VTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQ 503
T +Q ++ L+ P E T E + + L Q
Sbjct: 1479 PTTRSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSSASTYTQSLEQ 1538
Query: 504 VLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERL 561
+LN + E T++ L+ + + L ++ + + N E+++ L
Sbjct: 1539 LLNSPETKLEPPLWHAEFTKEELVQKLSSTTKSADHLNGLLRETEATNAILMEQIKLL 1596
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 64.3 bits (155), Expect = 7e-10
Identities = 84/397 (21%), Positives = 176/397 (44%), Gaps = 61/397 (15%)
Query: 225 HIMASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLH 284
H + + + P SP K Q S+E A A++R RL++ L
Sbjct: 222 HFLPHASSSAQSPCGSPGM---KRTESRQHLSVELADAKAKIR----------RLRQELE 268
Query: 285 ERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLK 344
E+ L+ K +L +++ + L Q+N +LS A A + + +EL A L+E++ + L+
Sbjct: 269 EKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR-DELDA-LREKAVRVDKLE 326
Query: 345 SQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE 404
S++ ++ ++ RVE+L+++ ++L + +LE L+ + + S +EL E
Sbjct: 327 SEVSRYKERLHDIEFYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDK--LHELEKE 383
Query: 405 QLQQQVSQLQDQLDAELEDKR-------KVLLELSREKAQNEDLKLEVTNILQKHKQEVE 457
LQ + +++ +++ K+ + LE++++++ +E L L E+E
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHL---------GWELE 434
Query: 458 LLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVS------ 511
+ + +S+ P + + ++E E + L++ + EL+ +
Sbjct: 435 QISRTSELSEAPQKSLGHEVNELTSSRLLKLE------MENQSLTKTVEELRTTVDSVEG 488
Query: 512 HAETTLELEKTRDML----------ILQRK--INVCYQEELEAMMTKADNDN--RDHKEK 557
+A L++EK L I+Q K + C + M KA + +E
Sbjct: 489 NASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN 548
Query: 558 LERLTRLLDLKNNRIKQLEGILRSHDLPTSE-QLKDV 593
ER ++L+ +N + Q LR ++E ++KD+
Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDI 585
Score = 55.8 bits (133), Expect = 3e-07
Identities = 95/381 (24%), Positives = 166/381 (43%), Gaps = 84/381 (22%)
Query: 231 TMQVEEPPKSPEKMWPKDENFEQR---SSLECA-QKAAELRASIKE-KVELIRLKKLLHE 285
T Q+E K ++ +EN E R SL+CA K A+L+ KE + E +LKK L
Sbjct: 686 TFQLESLEKENSQL--DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLEL 743
Query: 286 RNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKS 345
AS T+ ++ +Y+ L +NQ L E K++ +L +EL++ + +L+
Sbjct: 744 LKASFKKTE----RLEVSYQGLDIENQR-LQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Query: 346 QLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQ 405
LE+ LK +R+E LEKE K
Sbjct: 799 NLEE-------LKISSKRLEQLEKENK--------------------------------S 819
Query: 406 LQQQVSQLQ-DQLDAELEDKRKVLLELSREKAQNEDLKLEVTNI----LQKH----KQEV 456
L+Q+ SQL+ D+ E E+KR R++A+ +D LE N+ L+K +E+
Sbjct: 820 LEQETSQLEKDKKQLEKENKR------LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Query: 457 ELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETT 516
+ + + + +++++ A + T + E E+ K Q+ N+L+ + T
Sbjct: 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE----KLT 929
Query: 517 LELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLE-RLTRLLDLKNNRIKQL 575
ELE KI + + L + D+ + + KLE L + L++K +I L
Sbjct: 930 HELE----------KIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAAL 979
Query: 576 EGILR---SHDLPTSEQLKDV 593
E L +++ ++LK V
Sbjct: 980 EARLEESTNYNQQLRQELKTV 1000
Score = 52.8 bits (125), Expect = 2e-06
Identities = 77/341 (22%), Positives = 151/341 (44%), Gaps = 30/341 (8%)
Query: 265 ELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLK 324
ELR ++ + VE K L E+ + K ++ E + E +N LS
Sbjct: 478 ELRTTV-DSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA 536
Query: 325 QVNELRAELKEESKKAVSLKSQLED------VSILQMTLKEFQERVEDLEKERKLLNDNY 378
Q+ + L+E S++ + + Q + S+ Q + + RV+D+EKE K+L+
Sbjct: 537 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILH--- 593
Query: 379 DKLLESMLDSSDSSSQPHWSNELIAEQLQ--QQVSQLQDQLDAELEDKRKVLLELSREKA 436
ES+ ++S S+ + I ++L+ ++ + ++L+ EL K EL ++K
Sbjct: 594 ----ESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKEN-ELLQKKI 648
Query: 437 QNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSE---P 493
N + E L++ E+E +N ++ ++ +EN+Q++
Sbjct: 649 TNLKITCEKIEALEQENSELER-ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 494 KNQEEKKLSQV-LNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNR 552
+N E K + + + +LQ+ + E E E+ + L L K + E LE D +N
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL-KASFKKTERLEVSYQGLDIEN- 765
Query: 553 DHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDV 593
+RL + L+ N +I+QLE L+ ++ K++
Sbjct: 766 ------QRLQKTLENSNKKIQQLESELQDLEMENQTLQKNL 800
Score = 52.0 bits (123), Expect = 4e-06
Identities = 74/348 (21%), Positives = 160/348 (45%), Gaps = 30/348 (8%)
Query: 247 KDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTE-VQEAYE 305
++E +++ SL+ Q + + +KEK +L + + L E + + Q E + +
Sbjct: 511 ENEIVQEKQSLQNCQNLS--KDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVS 568
Query: 306 TLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVE 365
+L Q++Q A + + K+ L +KE S K ++ + + KE ER E
Sbjct: 569 SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 366 DLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKR 425
+LE E L + ++LL+ + + + + + E +L+++ +L+ LD+ ++
Sbjct: 629 ELENELHHL-EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDS-FKNLT 686
Query: 426 KVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAA-TISQPPDRQSEPATHPAVLQE 484
L L +E +Q ++ LE+ ++ VE L+ A+ ++Q E + L++
Sbjct: 687 FQLESLEKENSQLDEENLEL-------RRNVESLKCASMKMAQLQLENKELESEKEQLKK 739
Query: 485 NTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMM 544
++ + K E ++S +++ + TLE +KI ++LE+ +
Sbjct: 740 GLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS--------NKKI-----QQLESEL 786
Query: 545 TKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKD 592
+ +N+ ++ LE L + + R++QLE +S + TS+ KD
Sbjct: 787 QDLEMENQTLQKNLEE----LKISSKRLEQLEKENKSLEQETSQLEKD 830
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 64.3 bits (155), Expect = 7e-10
Identities = 84/397 (21%), Positives = 176/397 (44%), Gaps = 61/397 (15%)
Query: 225 HIMASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLH 284
H + + + P SP K Q S+E A A++R RL++ L
Sbjct: 222 HFLPHASSSAQSPCGSPGM---KRTESRQHLSVELADAKAKIR----------RLRQELE 268
Query: 285 ERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLK 344
E+ L+ K +L +++ + L Q+N +LS A A + + +EL A L+E++ + L+
Sbjct: 269 EKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYR-DELDA-LREKAVRVDKLE 326
Query: 345 SQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE 404
S++ ++ ++ RVE+L+++ ++L + +LE L+ + + S +EL E
Sbjct: 327 SEVSRYKERLHDIEFYKARVEELKEDNQVLLET-KTMLEDQLEGTRARSDK--LHELEKE 383
Query: 405 QLQQQVSQLQDQLDAELEDKR-------KVLLELSREKAQNEDLKLEVTNILQKHKQEVE 457
LQ + +++ +++ K+ + LE++++++ +E L L E+E
Sbjct: 384 NLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHL---------GWELE 434
Query: 458 LLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVS------ 511
+ + +S+ P + + ++E E + L++ + EL+ +
Sbjct: 435 QISRTSELSEAPQKSLGHEVNELTSSRLLKLE------MENQSLTKTVEELRTTVDSVEG 488
Query: 512 HAETTLELEKTRDML----------ILQRK--INVCYQEELEAMMTKADNDN--RDHKEK 557
+A L++EK L I+Q K + C + M KA + +E
Sbjct: 489 NASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLREN 548
Query: 558 LERLTRLLDLKNNRIKQLEGILRSHDLPTSE-QLKDV 593
ER ++L+ +N + Q LR ++E ++KD+
Sbjct: 549 SERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDI 585
Score = 55.8 bits (133), Expect = 3e-07
Identities = 96/381 (25%), Positives = 167/381 (43%), Gaps = 85/381 (22%)
Query: 231 TMQVEEPPKSPEKMWPKDENFEQR---SSLECA-QKAAELRASIKE-KVELIRLKKLLHE 285
T Q+E K ++ +EN E R SL+CA K A+L+ KE + E +LKK L
Sbjct: 686 TFQLESLEKENSQL--DEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLEL 743
Query: 286 RNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKS 345
AS T+ ++ +Y+ L +NQ L E K++ +L +EL++ + +L+
Sbjct: 744 LKASFKKTE----RLEVSYQGLDIENQR-LQKTLENSNKKIQQLESELQDLEMENQTLQK 798
Query: 346 QLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQ 405
LE+ LK +R+E LEKE K
Sbjct: 799 NLEE-------LKISSKRLEQLEKENK--------------------------------S 819
Query: 406 LQQQVSQLQ-DQLDAELEDKRKVLLELSREKAQNEDLKLEVTNI----LQKH----KQEV 456
L+Q+ SQL+ D+ E E+KR R++A+ +D LE N+ L+K +E+
Sbjct: 820 LEQETSQLEKDKKQLEKENKR------LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEI 873
Query: 457 ELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETT 516
+ + + + +++++ A + T + E E+ K Q+ N+L+ + T
Sbjct: 874 GIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE----KLT 929
Query: 517 LELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLE-RLTRLLDLKNNRIKQL 575
ELEK I K + + E+ D+ + + KLE L + L++K +I L
Sbjct: 930 HELEK-----IGLNKERLLHDEQ------STDDRYKLLESKLESTLKKSLEIKEEKIAAL 978
Query: 576 EGILR---SHDLPTSEQLKDV 593
E L +++ ++LK V
Sbjct: 979 EARLEESTNYNQQLRQELKTV 999
Score = 52.0 bits (123), Expect = 4e-06
Identities = 74/348 (21%), Positives = 160/348 (45%), Gaps = 30/348 (8%)
Query: 247 KDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTE-VQEAYE 305
++E +++ SL+ Q + + +KEK +L + + L E + + Q E + +
Sbjct: 511 ENEIVQEKQSLQNCQNLS--KDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVS 568
Query: 306 TLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVE 365
+L Q++Q A + + K+ L +KE S K ++ + + KE ER E
Sbjct: 569 SLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAE 628
Query: 366 DLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKR 425
+LE E L + ++LL+ + + + + + E +L+++ +L+ LD+ ++
Sbjct: 629 ELENELHHL-EKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDS-FKNLT 686
Query: 426 KVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAA-TISQPPDRQSEPATHPAVLQE 484
L L +E +Q ++ LE+ ++ VE L+ A+ ++Q E + L++
Sbjct: 687 FQLESLEKENSQLDEENLEL-------RRNVESLKCASMKMAQLQLENKELESEKEQLKK 739
Query: 485 NTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMM 544
++ + K E ++S +++ + TLE +KI ++LE+ +
Sbjct: 740 GLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS--------NKKI-----QQLESEL 786
Query: 545 TKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKD 592
+ +N+ ++ LE L + + R++QLE +S + TS+ KD
Sbjct: 787 QDLEMENQTLQKNLEE----LKISSKRLEQLEKENKSLEQETSQLEKD 830
Score = 43.9 bits (102), Expect = 0.001
Identities = 80/352 (22%), Positives = 157/352 (44%), Gaps = 42/352 (11%)
Query: 261 QKAAELRASIKEKVELIRLK----KLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILS 316
+ L+ KE EL++ K L LV K + ++ E L + + I
Sbjct: 878 ESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI-G 936
Query: 317 AAHEALL--KQVNELRAELKE---ESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKER 371
E LL +Q + R +L E ES SL+ + E ++ L+ L+E + L +E
Sbjct: 937 LNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 996
Query: 372 KLLNDNYDKLL-----ESMLDSSD--SSSQPHWSNELIAEQLQQQVSQLQDQL------D 418
K + NY+ L E M+ SS S W E +++ +++ +++D+L +
Sbjct: 997 KTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERE--SQETTRELLKVKDRLIEVERNN 1054
Query: 419 AELE-DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELL-QNAATISQPPDRQSEPA 476
A L+ +K+ + +L + + QN +L+ + IL +Q V L QN +Q Q E +
Sbjct: 1055 ATLQAEKQALKTQLKQLETQNNNLQAQ---ILALQRQTVSLQEQNTTLQTQNAKLQVENS 1111
Query: 477 T----HPAVLQENTQ--IEPSEPKNQEEK--KLSQVLNELQVSHAETTLELEKTRDMLIL 528
T +++ +N Q I+ S +N+ E K + L L S + +LE +
Sbjct: 1112 TLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQAS 1171
Query: 529 QRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILR 580
+ + + L++ + ++RD +++ +L + + +++ LE +L+
Sbjct: 1172 EYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLK----QKGQLEDLEKMLK 1219
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 64.3 bits (155), Expect = 7e-10
Identities = 119/579 (20%), Positives = 228/579 (39%), Gaps = 74/579 (12%)
Query: 42 NREELEDSFFRLREDHMLVKELSWKQQDEIKRLRTTLLRLT-----AAGRD-----LRVA 91
N +LE + +L+EDH +L KQ++E+ L+ L RL A G+ L+V
Sbjct: 1062 NDPQLEAEYQQLQEDHQRQDQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVE 1121
Query: 92 EEAAP---LSETARRGQKAGWRQRLSMHQRPQMHR-------------LQGHFHCVGPAS 135
++AA +S+ R+ + + R S ++ ++ R +Q +
Sbjct: 1122 KDAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVRPD 1181
Query: 136 PRR----AQPRVQV---------GHRQLHTAGAPVPEKPKRGPRDRLSYTAPPSFKEHAT 182
P+ A R+++ QL + + + +RGP+ + K
Sbjct: 1182 PKAESEVANLRLELVEQERKYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTD 1241
Query: 183 NENRGEVASKPSELVSGSNSIISFS-SVISMAKPIGLCMPNSAHIMASNT----MQVEEP 237
E E+ E+V + I + + K I + +Q +E
Sbjct: 1242 PEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQED 1301
Query: 238 PKSPEKMWPKDENF--EQRSSLECAQKAAELRASIKEKVE-LIRLKKLLHERNASLVMTK 294
P++ E++ EQ+ ++ ++ A I K E L R+K+ + ++
Sbjct: 1302 PQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVKERVVQQEV------ 1355
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
V+ E L+ + + + L+Q+++LRAEL+ ++ L+ QLE++ +
Sbjct: 1356 -----VRYEEEPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEELERER 1410
Query: 355 MTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQ--PHWSNELIAEQLQQQVSQ 412
+E + V+ L++ L + E + + Q P + E +LQ + Q
Sbjct: 1411 QARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQ 1470
Query: 413 LQDQ-LDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDR 471
+ Q L+ ELE R+ L L EKA+ ++ K+ ++ +Q K + E S +
Sbjct: 1471 HRRQLLEGELETLRRKLAAL--EKAEVKE-KVVLSESVQVEKGDTEQEIQRLKSSLEEES 1527
Query: 472 QSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNE----LQVSHAETTLELEKTRDMLI 527
+S+ V + ++ E N + K L E LQ+ LE +
Sbjct: 1528 RSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETRR------ 1581
Query: 528 LQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLD 566
LQ +IN+ E + + +H +L L R LD
Sbjct: 1582 LQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELD 1620
Score = 40.0 bits (92), Expect = 0.014
Identities = 87/415 (20%), Positives = 172/415 (41%), Gaps = 75/415 (18%)
Query: 237 PPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKL-----LHERN--AS 289
PP PE + D Q S+ QKAA + +++++ E+++ + L R A
Sbjct: 453 PPTDPEALALADSLGSQYRSVR--QKAAGSKRTLQQRYEVLKTENPGDASDLQGRQLLAG 510
Query: 290 LVMTKAQLTEVQEAYETLL----QKNQGILSAAHEAL-LKQVNELRAELKEESKKAVS-- 342
L + L ++A +L ++ + + +A A LK + ++ E ++ +
Sbjct: 511 LDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIEPEKTRSTAEG 570
Query: 343 ---------------LKSQLEDVS-----ILQMTLKEFQERVEDLEKERKLLNDNYDKLL 382
L++++ED + +LQ+ L QE+V+ + K L +++ L
Sbjct: 571 EAFIQALPGSGTTPLLRTRVEDTNRKYEHLLQL-LDLAQEKVDVANRLEKSLQQSWELLA 629
Query: 383 --ESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQ--LDAELEDKRKVLLE-------- 430
E+ L+ D+ + + ++L +LQ Q L E+E + +
Sbjct: 630 THENHLNQDDTVPESSRVLDSKGQELAAMACELQAQKSLLGEVEQNLQAAKQCSSTLASR 689
Query: 431 -------LSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQ 483
L R++A+ L N+ Q+ ++ + LQ+A + R H VLQ
Sbjct: 690 FQEHCPDLERQEAEVHKLGQRFNNLRQQVERRAQSLQSAKAAYEHFHRG-----HDHVLQ 744
Query: 484 ENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAM 543
I EP QE LSQ+ E ++ + + L+ +R+ + +KI Q+ +A+
Sbjct: 745 FLVSIPSYEP--QETDSLSQM--ETKLKNQKNLLDEIASREQEV--QKICANSQQYQQAV 798
Query: 544 MTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDVAYGTR 598
+D++ + E+L LLDL+N R + R T + ++ A +
Sbjct: 799 --------KDYELEAEKLRSLLDLENGRSSHVSKRARLQSPATKVKEEEAALAAK 845
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 63.5 bits (153), Expect = 1e-09
Identities = 86/396 (21%), Positives = 177/396 (44%), Gaps = 67/396 (16%)
Query: 253 QRSSLECAQKAAELRASIKEKV-ELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
Q LE A +++L + + +K +L+ L+K L E+ + A+ E+++ L++KN
Sbjct: 675 QEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQE---LMEKN 731
Query: 312 QGILSAA------------------------HEALLKQVNELRAELKEESKKAVSLKSQL 347
+ I S H+ + KQ+ L A+L+ KK K Q
Sbjct: 732 EKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLE---KKDQQFKEQE 788
Query: 348 EDVSILQMTLKEFQERVEDLEK-------ERKLLNDNYDKLLESMLDSSDSSS----QPH 396
+ +S+LQ + Q +E L++ E K N D+ L+++ + + Q
Sbjct: 789 KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLD 848
Query: 397 WSNELIAEQLQQQVSQLQ---DQLDAELEDKRKVLLELSRE-KAQNEDL-KLEVTNILQK 451
+ E+ E+L ++QL+ ++ + +L+ K + + L +E K +N L + N++ +
Sbjct: 849 SALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQ 908
Query: 452 H---KQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNEL 508
H +Q+ L Q + D Q++ + L++ Q + + +KL ++ +
Sbjct: 909 HTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQ----KQRESSAEKLRKMEEKC 964
Query: 509 QVSHAETTLELEKTRDMLILQRKINV---CYQEELEAMMTKADNDNRDHKEKLERLTRL- 564
+ + E L+ +K ++ R++ + Y+EEL M + + RD + K L++L
Sbjct: 965 ESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLD 1024
Query: 565 ---------LDLKNNRIKQLEGILRSHDLPTSEQLK 591
L+ K N +K+LE + S + +E L+
Sbjct: 1025 MILDQTKTELEKKTNAVKELEKLQHSTETELTEALQ 1060
Score = 47.4 bits (111), Expect = 9e-05
Identities = 87/406 (21%), Positives = 173/406 (42%), Gaps = 60/406 (14%)
Query: 265 ELRASIKEKVELIR-LKKLLHERNASLV--MTKAQL--TEVQEAYETL------LQKNQG 313
+ + +++K ++ L+KL H L + K ++ TE+Q A+ L LQ+ +
Sbjct: 1029 QTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRD 1088
Query: 314 ILSAAHEALLKQ---VNELRAELKE-----ESKKAV-------------SLKSQLEDVSI 352
+L A +L ++ + +L AEL+E E KK LK + V+
Sbjct: 1089 VLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTH 1148
Query: 353 LQMTLKEFQERVED--------LEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE 404
L MT++E + +E LEK L + +K +ES+ D ++ + E I
Sbjct: 1149 LDMTIREHRGEMEQKIIKLEGTLEKSELELKE-CNKQIESLNDKLQNAKEQLREKEFIML 1207
Query: 405 QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAAT 464
Q +Q++SQL+ +++ + +++ + ++ E ++ Q+ + E +QN+ T
Sbjct: 1208 QNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHT 1267
Query: 465 ISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRD 524
+ A H V Q +IE + ++ K+LS+ + +H L K R+
Sbjct: 1268 -------ELAEARHQQV-QAQREIERLSSELEDMKQLSKE-KDAHGNHLAEELGASKVRE 1318
Query: 525 MLI---LQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRS 581
+ +Q +I E+E++ + H+E + D + + ++QL L
Sbjct: 1319 AHLEARMQAEIKK-LSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEK 1377
Query: 582 HDLPTSEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLLHQGENL 627
L E V+ + + E + A + +LL +GEN+
Sbjct: 1378 AKLELEEAQDTVSNLHQQVQDRNEVIEAANE------ALLTKGENV 1417
Score = 45.1 bits (105), Expect = 4e-04
Identities = 82/385 (21%), Positives = 162/385 (42%), Gaps = 55/385 (14%)
Query: 233 QVEEPPKSPEKMWPKDENF-EQRSSLECAQKAAELRASIKEKVELI------RLKKLLHE 285
Q+E EK KD+ F EQ ++ Q+ + E ++ + +KK +
Sbjct: 769 QIERLEAQLEK---KDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMK 825
Query: 286 RNASLVMTKAQLTEVQEAYETL-LQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLK 344
++ +L + Q++E ET+ +++ L E L+ +N+L KE+ +K LK
Sbjct: 826 KDEALKALQNQVSE-----ETIKVRQLDSALEICKEELVLHLNQLEGN-KEKFEK--QLK 877
Query: 345 SQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE 404
+ E+V LQ LK +++ ++ +L + + + + + + + + +
Sbjct: 878 KKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEK 937
Query: 405 QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLK----LEVTNILQKHKQEV---- 456
Q+ + +LQ Q ++ E RK + E A DLK +E+T ++ K E+
Sbjct: 938 QVSKLEQELQKQRESSAEKLRK-MEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYK 996
Query: 457 -ELLQNAATISQPPDRQSEPATHPAVL-----QENTQIEPSEPKNQEEKKLS-------- 502
EL + I A H + L Q T++E +E +KL
Sbjct: 997 EELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELT 1056
Query: 503 ------QVL-NELQVSHAETTLELEKTRDMLILQRKINVCYQE------ELEAMMTKADN 549
+VL ELQ +H E L + +++ + +K + +E +L A + +
Sbjct: 1057 EALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKM 1116
Query: 550 DNRDHKEKLERLTRLLDLKNNRIKQ 574
+ D K++L + + L +N +KQ
Sbjct: 1117 EIEDKKQELLEMDQALKERNWELKQ 1141
Score = 43.5 bits (101), Expect = 0.001
Identities = 79/386 (20%), Positives = 163/386 (42%), Gaps = 49/386 (12%)
Query: 162 KRGPRDRL-SYTAPPSFKEHATNENRGEVASKPSELVSGSNSI------ISFSSVISMAK 214
++ PRD++ S +AP + + E ++ + + LV+ ++S+ I F S AK
Sbjct: 213 QKKPRDKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAK 272
Query: 215 PIGLCMPN----SAHIMASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASI 270
L S I+ + +E + +K+ + EN ++S +K L+ S
Sbjct: 273 VSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQES- 331
Query: 271 KEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELR 330
K E I+LK L L + ++ Q+N+ + +A E L K + +
Sbjct: 332 --KEECIKLKVDL-------------LEQTKQGKRAERQRNEALYNA--EELSKAFQQYK 374
Query: 331 AELKEESKKAVSLKSQLE-DVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSS 389
++ E+ +K + + LE +++ + K QER + E ++L + +L E +
Sbjct: 375 KKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGK 434
Query: 390 DSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNIL 449
+ N + QL + + +L++ELE+K ++L + +N +LK+ V
Sbjct: 435 EKLRIMAVKNSEVMAQLTESRQSIL-KLESELENKDEILRDKFSLMNENRELKVRVA--- 490
Query: 450 QKHKQEVELLQNAATISQPPDRQSEPATHPAVLQEN--------TQIEPSEPKNQEEKKL 501
+ ++L Q S+ R E L+ ++ + S N+E++ +
Sbjct: 491 -AQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCI 549
Query: 502 ------SQVLNELQVSHAETTLELEK 521
V++EL++ A E++K
Sbjct: 550 GCCEANKLVISELRIKLAIKEAEIQK 575
Score = 43.1 bits (100), Expect = 0.002
Identities = 57/232 (24%), Positives = 104/232 (44%), Gaps = 31/232 (13%)
Query: 357 LKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQ--LQ 414
+K +E++ L ++ L L+ +Q ++ QQ S L+
Sbjct: 231 IKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILE 290
Query: 415 DQ---LDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQE-----VELLQNAATIS 466
+Q L+AE+ + KVL E + Q++ + +E LQ+ K+E V+LL+
Sbjct: 291 EQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQ-G 349
Query: 467 QPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKT---R 523
+ +RQ A + A E S+ Q +KK+++ L ++Q E LE T +
Sbjct: 350 KRAERQRNEALYNAE-------ELSKAFQQYKKKVAEKLEKVQAE--EEILERNLTNCEK 400
Query: 524 DMLILQRKINVCYQEELEAMMTK---ADNDNRDHKEKLERLTRLLDLKNNRI 572
+ LQ + + Y+ ELE + K +N + KEKL R++ +KN+ +
Sbjct: 401 ENKRLQERCGL-YKSELEILKEKLRQLKEENNNGKEKL----RIMAVKNSEV 447
Score = 42.7 bits (99), Expect = 0.002
Identities = 60/306 (19%), Positives = 129/306 (42%), Gaps = 26/306 (8%)
Query: 305 ETLLQKNQGILSAAHEA----LLKQVNELRAEL----KEESKKAVSLKSQLEDVSILQMT 356
E++ +NQ ++ +E L+ + ELR +L E S V++ + ++Q
Sbjct: 618 ESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEE 677
Query: 357 LKEFQERVEDLEKER-----KLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVS 411
L E LE E +LL +K LE + + S + + E + +++
Sbjct: 678 LLEKASNSSKLESEMTKKCSQLLT--LEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIR 735
Query: 412 QLQDQLDAELEDKRKVLLELSREKA----QNEDLKLEVTNI-LQKHKQEVELLQNAATIS 466
L+ ++ E E K+ L + K Q+++++ ++ + Q K++ + + T+S
Sbjct: 736 SLETNINTEHE---KICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMS 792
Query: 467 QPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDML 526
H L E K + KK + L LQ +E T+++ + L
Sbjct: 793 MLQQDIICKQHHLESLDRLLTESKGEMKKENMKK-DEALKALQNQVSEETIKVRQLDSAL 851
Query: 527 ILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQL--EGILRSHDL 584
+ ++ V + +LE K + + E++ L + L +KN+ +++ + ++ H L
Sbjct: 852 EICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTL 911
Query: 585 PTSEQL 590
+Q+
Sbjct: 912 QQQQQM 917
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 62.8 bits (151), Expect = 2e-09
Identities = 92/417 (22%), Positives = 183/417 (43%), Gaps = 81/417 (19%)
Query: 253 QRSSLECAQKAA--ELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQK 310
+RS E + AA +L + +E + +K HE+ ++ +++E +E
Sbjct: 818 ERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEK---------EVNQLREKWEKERSW 868
Query: 311 NQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDV------SILQMTLKEFQERV 364
+Q L+ A E+L ++ EL LKE+ + ++++Q E+ ++ QM L+ +ERV
Sbjct: 869 HQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERV 928
Query: 365 EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQ--QVSQLQDQ-----L 417
LE LL++ + +D+S Q E+L+Q +V +L++Q L
Sbjct: 929 SLLET-----------LLQTQKELADASQQ--------LERLRQDMKVQKLKEQETTGIL 969
Query: 418 DAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPAT 477
+L++ ++ L E +R+ + E ++ L + K +++ +Q E
Sbjct: 970 QTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQ-------------KQVEDLK 1016
Query: 478 HPAVLQENTQI---EPSEPKNQEEKKLSQVLNELQVSHAETTLEL-EKTRDMLILQRKIN 533
V Q+++Q + + K +E ++ +++ EL+ A TL L EK + +L+LQ +
Sbjct: 1017 SQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADS 1076
Query: 534 VCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQLKDV 593
+ Q+EL A+ + KE L+ ++L +K+ E + + E+L+
Sbjct: 1077 I-RQQELSALRQDMQEAQGEQKE----LSAQMELLRQEVKEKEADFLAQEAQLLEELE-- 1129
Query: 594 AYGTRPLSLCLETLPAHGDEDKVDISLLHQGENLFELHIHQAFLTSAALAQAGDTQP 650
+H E ++ SL Q +L + S A A + QP
Sbjct: 1130 --------------ASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQP 1172
Score = 59.3 bits (142), Expect = 2e-08
Identities = 92/424 (21%), Positives = 182/424 (42%), Gaps = 67/424 (15%)
Query: 218 LCMPNSAHIMASNTMQVE--EPPKSPEKMWPKDENFEQRSSLECAQKA-AELRASIKEKV 274
+C A A N +QV+ E K E +W K+ + E + L+ A++A AEL+A +++
Sbjct: 629 VCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLE--AQLQKAEEAGAELQADLRD-- 684
Query: 275 ELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELK 334
+ E + ++ QEA T L++ E L + V E A ++
Sbjct: 685 --------IQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVR 736
Query: 335 EESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQ 394
E++ V L++ D ++ E+++ L ++LL S+ ++ +S
Sbjct: 737 EKAALEVRLQAVERD-------RQDLAEQLQGLSSAKELLES-------SLFEAQQQNSV 782
Query: 395 PHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQK--- 451
+ + Q+Q V+Q ++ + E+ R + LEL E++Q E + L +
Sbjct: 783 IEVTKGQLEVQIQT-VTQAKEVIQGEV---RCLKLELDTERSQAEQERDAAARQLAQAEQ 838
Query: 452 ------------HKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEK 499
H++EV L+ + +Q ++ +E ++E + Q E
Sbjct: 839 EGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEM 898
Query: 500 KLSQVLNELQVSHAETTL---ELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKE 556
+ Q E + + AE+ L +LE ++ + L LE ++ + + D +
Sbjct: 899 EAIQAQREEERTQAESALCQMQLETEKERVSL-----------LETLL-QTQKELADASQ 946
Query: 557 KLERLTRLLDLKNNRIKQLE--GILRSHDLPTSEQLKDVAYGTRPLSLCLETLPAHGDED 614
+LERL + D+K ++K+ E GIL++ +LK+ A R L+ + +D
Sbjct: 947 QLERLRQ--DMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQD 1004
Query: 615 KVDI 618
K+D+
Sbjct: 1005 KMDL 1008
Score = 50.4 bits (119), Expect = 1e-05
Identities = 81/361 (22%), Positives = 150/361 (41%), Gaps = 44/361 (12%)
Query: 252 EQRSSLECAQKAAELRASIKE--KVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ 309
E +EC QK + +E +V L L L ER+ L +Q+ ++ E++ T+L
Sbjct: 1564 ENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDL-ESHSTVLA 1622
Query: 310 KNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVED--- 366
+ EL+E ++ S + Q+E++ + L + ER +
Sbjct: 1623 R---------------------ELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELM 1661
Query: 367 LEKER-KLLNDN---YDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
L+KER ++L D K+LE L+ S + QL Q+ ++
Sbjct: 1662 LQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQR 1721
Query: 423 DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVEL-LQNA-ATISQPPDRQSEPATHPA 480
+ + + R+K + + + E + LQ+ K ++E LQ + + S+
Sbjct: 1722 GSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIV 1781
Query: 481 VLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEEL 540
VLQ+ Q E E +E+ L L+E Q + A+ ELE + + +E+
Sbjct: 1782 VLQQQLQ-EAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKA 1840
Query: 541 EAM----------MTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSEQL 590
+A+ + + + +DHKE+ RL L ++ R++ LE +L + EQ
Sbjct: 1841 DALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQE 1900
Query: 591 K 591
K
Sbjct: 1901 K 1901
Score = 49.3 bits (116), Expect = 2e-05
Identities = 77/363 (21%), Positives = 144/363 (39%), Gaps = 63/363 (17%)
Query: 260 AQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAH 319
A A L ++ ++LK E + E++ A LQ+N +L+
Sbjct: 1371 ASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTL 1430
Query: 320 EALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKE-------FQERVEDLEKERK 372
++V LR +++E K+ K+ LE +L + LK+ QE++++LEK R
Sbjct: 1431 AEREEEVETLRGQIQELEKQREMQKAALE---LLSLDLKKRNQEVDLQQEQIQELEKCRS 1487
Query: 373 LL---------------------------NDNYDKLLESMLDSSDSSSQPHWSNELIAEQ 405
+L + +LE L + Q S +
Sbjct: 1488 VLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQD 1547
Query: 406 LQQQVSQLQ------DQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELL 459
L++Q+ L+ ++ ++E ++K++ EL ++ +T L++ QE++
Sbjct: 1548 LKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQ-- 1605
Query: 460 QNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLEL 519
A SQ D +S H VL Q E K+Q E+ + ELQ T +L
Sbjct: 1606 ---AQSSQIHDLES----HSTVLARELQERDQEVKSQREQ-----IEELQRQKEHLTQDL 1653
Query: 520 EKTRDMLILQRKINVCYQEELEAMMTKADNDNRDH-----KEKLERLTRLLDLKNNRIKQ 574
E+ RD ++ +K + E+ TK ++ + +E+ LT L R ++
Sbjct: 1654 ER-RDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEE 1712
Query: 575 LEG 577
+G
Sbjct: 1713 GKG 1715
Score = 48.1 bits (113), Expect = 5e-05
Identities = 95/373 (25%), Positives = 153/373 (41%), Gaps = 85/373 (22%)
Query: 247 KDENFEQRSSLECAQKAAELRASIKEKVEL-IRLKKLLHERNASLVMTKAQLTEVQEAYE 305
K +N E S E AQ +++E+ EL + K L E A L T L E +E E
Sbjct: 1389 KLKNEEVESERERAQ-------ALQEQGELKVAQGKALQENLALLTQT---LAEREEEVE 1438
Query: 306 TL------LQKNQGILSAAHEAL---LKQVNE---LRAELKEESKKAVSLKSQLE-DVSI 352
TL L+K + + AA E L LK+ N+ L+ E +E +K S+ L V
Sbjct: 1439 TLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQE 1498
Query: 353 LQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQ 412
+ L +E++ +LEK+R+ + +LE L + Q S + L++Q+
Sbjct: 1499 REQKLTVQREQIRELEKDRETQRN----VLEHQLLELEKKDQMIESQRGQVQDLKKQLVT 1554
Query: 413 LQ------DQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATIS 466
L+ ++ ++E ++K++ EL ++ +T L++ QE++ A S
Sbjct: 1555 LECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQ-----AQSS 1609
Query: 467 QPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDML 526
Q D +S H VL Q E K+Q E+ + ELQ T +LE+ L
Sbjct: 1610 QIHDLES----HSTVLARELQERDQEVKSQREQ-----IEELQRQKEHLTQDLERRDQEL 1660
Query: 527 ILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGIL------- 579
+LQ+ ER+ L D + + K LE L
Sbjct: 1661 MLQK----------------------------ERIQVLEDQRTRQTKILEEDLEQIKLSL 1692
Query: 580 --RSHDLPTSEQL 590
R +L T QL
Sbjct: 1693 RERGRELTTQRQL 1705
Score = 44.3 bits (103), Expect = 8e-04
Identities = 86/364 (23%), Positives = 154/364 (42%), Gaps = 52/364 (14%)
Query: 249 ENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLV--MTKAQLTEVQEAYET 306
+N E++S E Q + E E +EL HE ASL + +A+L ++
Sbjct: 1296 QNQEEKSKWEGKQNSLE-----SELMEL-------HETMASLQSRLRRAELQRMEA---- 1339
Query: 307 LLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVED 366
Q + +L AA E L QV L+A + E +A + ED+ + LK E VE
Sbjct: 1340 --QGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVES 1397
Query: 367 -------LEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDA 419
L+++ +L L E++ + + ++ E E L+ Q+ +L+ Q
Sbjct: 1398 ERERAQALQEQGELKVAQGKALQENLALLTQTLAE----REEEVETLRGQIQELEKQ--R 1451
Query: 420 ELEDKRKVLLELSREKAQNE-DLKLEVTNILQKHKQEVELLQNAA-------TISQPPDR 471
E++ LL L +K E DL+ E L+K + +E L A T+ + R
Sbjct: 1452 EMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIR 1511
Query: 472 QSEP--ATHPAVLQEN-TQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLIL 528
+ E T VL+ ++E + + ++ Q L + V+ LELE+ +
Sbjct: 1512 ELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMEC 1571
Query: 529 QRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSE 588
Q+K+ + + E + D LE ++ L ++++I LE SH +
Sbjct: 1572 QQKLIKELEGQRETQRVALTHLTLD----LEERSQELQAQSSQIHDLE----SHSTVLAR 1623
Query: 589 QLKD 592
+L++
Sbjct: 1624 ELQE 1627
Score = 41.2 bits (95), Expect = 0.006
Identities = 57/232 (24%), Positives = 100/232 (43%), Gaps = 34/232 (14%)
Query: 252 EQRSSLECAQKAAE--------LRASIKEKV-ELIRLKKLLHERNASLVMTKAQLTEVQE 302
EQ+ L A + E L A E + ELI L++ L + + + + TEV
Sbjct: 509 EQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTA 568
Query: 303 AYETLLQKNQGI--LSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEF 360
A L + Q I LS++ L +V +LRA + S A++ L+ V + Q L+
Sbjct: 569 A---LARAEQSIAELSSSENTLKTEVADLRAAAVKLS--ALNEALALDKVGLNQQLLQLE 623
Query: 361 QE------RVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQ 414
+E R+E E+ R L + L ++ + W E Q+ +
Sbjct: 624 EENQSVCSRMEAAEQARNALQVD--------LAEAEKRREALWEKNTHLEAQLQKAEEAG 675
Query: 415 DQLDAEL----EDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNA 462
+L A+L E+K ++ +LS + Q E ++ + Q+ K++ E+L A
Sbjct: 676 AELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARA 727
Score = 40.8 bits (94), Expect = 0.008
Identities = 111/542 (20%), Positives = 210/542 (38%), Gaps = 106/542 (19%)
Query: 53 LREDHMLVKELSWKQQDEIKRLRTTLLRLTAAGRDLRVAEEA-APLSETARRGQKAGWRQ 111
L + HM +KE + QD ++ R L GR ++ EE L +R +KA
Sbjct: 1847 LEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLAL 1906
Query: 112 RLSMHQRPQMHRLQGHFHCVGPASPRRAQPRVQVGHRQLHT--AGAPVPEKPKRGPRDRL 169
+ ++ Q H ++ S +AQ ++ ++L A + + R R
Sbjct: 1907 QQQCAEQAQEHEVETR---ALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARA 1963
Query: 170 SYTAPPSFKEHATNENRGEVASKPSELVSGSNSIISFSSVISMAKPIGLCMPNSAHIMAS 229
K HA + + + + +EL S S+ +S ++ + C +S + +
Sbjct: 1964 EALQEALGKAHAALQGKEQHLLEQAEL---SRSL--EASTATLQASLDACQAHSRQLEEA 2018
Query: 230 NTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNAS 289
+Q E Q L + +L+ ++ ++ E +R H++
Sbjct: 2019 LRIQ---------------EGEIQDQDLRYQEDVQQLQQALAQRDEELR-----HQQERE 2058
Query: 290 LVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLED 349
++ K+ VQ E ++Q+ Q L E +EE ++ +
Sbjct: 2059 QLLEKSLAQRVQ---ENMIQEKQ---------------NLGQEREEE-----EIRGLHQS 2095
Query: 350 VSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQ 409
V LQ+TL + ++ + +L + ++ N LE++ S +S P L + L+ +
Sbjct: 2096 VRELQLTLAQKEQEILELRETQQRNN------LEALPHSHKTS--PMEEQSLKLDSLEPR 2147
Query: 410 VSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPP 469
+ + ++L A L +E REKAQ+ L L T QEV + A+ + +
Sbjct: 2148 LQRELERLQAALRQTEAREIEW-REKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDS 2206
Query: 470 DRQ-------------------SEPATHPAVL----QENTQI--------EPSEPKNQEE 498
++Q S AT A L ++ Q+ EPS P E+
Sbjct: 2207 EQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPS-PDGMEK 2265
Query: 499 KKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKL 558
+ Q L LQ A LE++++R LQR + +L + + + + + R K +
Sbjct: 2266 QSWRQRLEHLQ--QAVARLEIDRSR----LQR-----HNVQLRSTLEQVERERRKLKREA 2314
Query: 559 ER 560
R
Sbjct: 2315 MR 2316
Score = 32.7 bits (73), Expect = 2.3
Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 403 AEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNA 462
A + Q++ QL+ Q D E + + + ELS Q++ + +++ ++ VE+L+
Sbjct: 260 AHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILET- 318
Query: 463 ATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVL-----NELQVSHAETTL 517
+E H A L N Q E Q K ++QV+ N Q S E +L
Sbjct: 319 --------NHTELMEHEASLSRNAQ-EEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSL 369
Query: 518 ELEKT 522
EL+ +
Sbjct: 370 ELDSS 374
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 62.4 bits (150), Expect = 3e-09
Identities = 91/364 (25%), Positives = 145/364 (39%), Gaps = 59/364 (16%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNAS-----LVMTKAQLTEVQEAYET 306
E +L+ ELRA K + E+ LKK L E S M + V+E E
Sbjct: 1154 ELEDTLDSTATQQELRA--KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1211
Query: 307 L---------LQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDV----SIL 353
L L KN+ L + L ++ L +E K L++Q++++ S
Sbjct: 1212 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG 1271
Query: 354 QMTLKEFQERVEDLEKERK----LLNDNYDKLLESMLDSSDSSSQPHWSNELIAE----- 404
+ E ++V L+ E + +LN+ K ++ D + SSQ + EL+ E
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Query: 405 --------QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEV 456
QL+++ + LQDQLD E+E K+ + +S Q D K + LQ V
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKK----LQDFASTV 1387
Query: 457 ELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETT 516
E L+ Q ++ E T + E K KL + N LQ +
Sbjct: 1388 EALEEGKKRFQ---KEIENLT-----------QQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
Query: 517 LELEKTRDMLI----LQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRI 572
++L+ R ++ QRK + EE AD +R E E+ T+ L L
Sbjct: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
Query: 573 KQLE 576
+ LE
Sbjct: 1494 EALE 1497
Score = 56.2 bits (134), Expect = 2e-07
Identities = 84/384 (21%), Positives = 166/384 (43%), Gaps = 36/384 (9%)
Query: 227 MASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHER 286
MA + +EE + E K + + + + + E+ + +L + +KLL ER
Sbjct: 948 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 1007
Query: 287 NASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVS-LKS 345
+ L A+ E ++A KN L HE+++ ++ E+R + +E+S++ + LK
Sbjct: 1008 ISDLTTNLAE--EEEKA------KNLTKLKNKHESMISEL-EVRLKKEEKSRQELEKLKR 1058
Query: 346 QLE-DVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE 404
+LE D S + + Q ++ +L+ + L ++L ++ D +Q + + + I E
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQ---LAKKEEELQAALARLDDEIAQKNNALKKIRE 1115
Query: 405 QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQ----------KHKQ 454
L+ +S LQ+ LD+E + K + + E LK E+ + L K +Q
Sbjct: 1116 -LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Query: 455 EVELLQNA---ATISQPPDRQSEPATHPAVLQENT-QIEPSEPKNQEEKKLSQVLNELQV 510
EV +L+ A T S Q H ++E T Q+E + K Q L +
Sbjct: 1175 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1234
Query: 511 SHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNN 570
A L + + + ++K +EL++ + + + +K+ +L N
Sbjct: 1235 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL-------QN 1287
Query: 571 RIKQLEGILRSHDLPTSEQLKDVA 594
++ + G+L + + KDVA
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVA 1311
Score = 51.6 bits (122), Expect = 5e-06
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 36/294 (12%)
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
+ L + Q ++ LL + + I S + + + AE +E+ KA+SL LE
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYAD----ERDRAEAEAREKETKALSLARALE------ 1493
Query: 355 MTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQ---QVS 411
E E E+LE+ K+L + L+ S D + + S + Q+++ Q+
Sbjct: 1494 ----EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
Query: 412 QLQDQLDAELEDKRKVLL-----------ELSREKAQNEDLKLEVTNILQKHKQEVELLQ 460
+L+D+L A + K ++ + +L QNE+ + ++ L +++ E+E +
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER 1609
Query: 461 NAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELE 520
++ ++ E LQ ++ I+ E ++ +KL + + Q +
Sbjct: 1610 KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ----RELEDAR 1665
Query: 521 KTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQ 574
+RD + K N + LEA + + D ER + DL+ + +
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQED----LAAAERARKQADLEKEELAE 1715
Score = 50.8 bits (120), Expect = 8e-06
Identities = 81/384 (21%), Positives = 159/384 (41%), Gaps = 61/384 (15%)
Query: 250 NFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ 309
N + +++ A+ A L + +++ EL L E + +L +++E +L
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQDTQEL------LQEETRQKLNVSTKLRQLEEERNSLQD 1350
Query: 310 KNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEK 369
+ + A L + ++ L +L + KK S +E L+ K FQ+ +E+L +
Sbjct: 1351 QLDEEMEAKQN-LERHISTLNIQLSDSKKKLQDFASTVE---ALEEGKKRFQKEIENLTQ 1406
Query: 370 ERKLLNDNYDKL------LESMLDS------------SDSSSQPHWSNELIAEQ--LQQQ 409
+ + YDKL L+ LD S+ + ++L+AE+ + +
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
Query: 410 VSQLQDQLDAELEDKRKVLLELSR--EKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ 467
+ +D+ +AE +K L L+R E+A +LE TN + K + E +L+ + + +
Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME-DLVSSKDDVGK 1525
Query: 468 PPDR--QSEPATHPAVLQENTQIEPSEPKNQ--EEKKLSQVLN----------------- 506
+S+ A + + TQ+E E + Q E+ KL +N
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 507 -------ELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLE 559
+LQ E ELE R L + +L+ + +AD+ + +E ++
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 560 RLTRLLDLKNNRIKQLEGILRSHD 583
+L +L + ++LE S D
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRD 1669
Score = 47.4 bits (111), Expect = 9e-05
Identities = 66/326 (20%), Positives = 138/326 (42%), Gaps = 73/326 (22%)
Query: 266 LRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAH--EALL 323
L +K +++ R ++ + + L TK + + + + L QK+ + + + L
Sbjct: 837 LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896
Query: 324 KQVNELRAELKEESKKAVSLKSQLEDV-SILQMTLKEFQERVEDLEKERKLLNDNYDKLL 382
+ EL AE +E + + K +LE++ ++ L+E ++R + L+ ERK K+
Sbjct: 897 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK-------KMA 949
Query: 383 ESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLK 442
+ MLD L++QL+ E ++K+ LE +A+ + L+
Sbjct: 950 QQMLD-------------------------LEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
Query: 443 LEV------TNILQKHKQEV-ELLQNAATISQPPDRQSEPAT-----HPAVLQE-NTQIE 489
E+ N L K ++ + E + + T + +++ T H +++ E +++
Sbjct: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
Query: 490 PSEPKNQEEKKLSQVLN-----------ELQVSHAETTLELEKTRDMLILQRKINVCYQE 538
E QE +KL + L +LQ AE ++L K +E
Sbjct: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKK--------------EE 1090
Query: 539 ELEAMMTKADNDNRDHKEKLERLTRL 564
EL+A + + D++ L+++ L
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIREL 1116
Score = 45.4 bits (106), Expect = 3e-04
Identities = 65/335 (19%), Positives = 134/335 (40%), Gaps = 26/335 (7%)
Query: 260 AQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ---KNQGILS 316
A + A+LR + + + ++ L R+ + QL YET L+ K + + +
Sbjct: 1557 ATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAA 1616
Query: 317 AAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDL--------- 367
AA + L + +L + K QL LQ +K+FQ +ED
Sbjct: 1617 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRK---LQAQMKDFQRELEDARASRDEIFA 1673
Query: 368 -----EKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
EK+ K L + +L E + + + Q E +AE+L +S ++ L E
Sbjct: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG-RNALQDEKR 1732
Query: 423 DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVL 482
+ +L E + + +++ ++K Q+ E L N + +++E A
Sbjct: 1733 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
Query: 483 Q-ENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELE 541
Q + + + E + + K + L+ A+ ++E+ K ++L+
Sbjct: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
Query: 542 AMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
++ + + D ++ E+ + N R+KQL+
Sbjct: 1853 EILLQVE----DERKMAEQYKEQAEKGNARVKQLK 1883
Score = 42.4 bits (98), Expect = 0.003
Identities = 49/210 (23%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 254 RSSLECAQKAAELR-ASIKEKVELIRLK-KLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
R++L+ ++ E R A ++E++E + + + +R QL+ + QKN
Sbjct: 1724 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1783
Query: 312 QGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKER 371
+ +A + L +Q ELR++L E + AV K + ++ L+ + + +E+VE +E+
Sbjct: 1784 E----SARQQLERQNKELRSKL-HEMEGAVKSKFK-STIAALEAKIAQLEEQVEQEAREK 1837
Query: 372 ----KLLNDNYDKLLESMLDSSDSSSQPHWSNELI------AEQLQQQVSQLQDQLDAEL 421
K L KL E +L D E +QL++Q+ + +++
Sbjct: 1838 QAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRIN 1897
Query: 422 EDKRKVLLELSREKAQNEDLKLEVTNILQK 451
++RK+ EL NE + EV + K
Sbjct: 1898 ANRRKLQRELDEATESNEAMGREVNALKSK 1927
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 62.4 bits (150), Expect = 3e-09
Identities = 91/364 (25%), Positives = 145/364 (39%), Gaps = 59/364 (16%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNAS-----LVMTKAQLTEVQEAYET 306
E +L+ ELRA K + E+ LKK L E S M + V+E E
Sbjct: 1161 ELEDTLDSTATQQELRA--KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1218
Query: 307 L---------LQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDV----SIL 353
L L KN+ L + L ++ L +E K L++Q++++ S
Sbjct: 1219 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG 1278
Query: 354 QMTLKEFQERVEDLEKERK----LLNDNYDKLLESMLDSSDSSSQPHWSNELIAE----- 404
+ E ++V L+ E + +LN+ K ++ D + SSQ + EL+ E
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Query: 405 --------QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEV 456
QL+++ + LQDQLD E+E K+ + +S Q D K + LQ V
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKK----LQDFASTV 1394
Query: 457 ELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETT 516
E L+ Q ++ E T + E K KL + N LQ +
Sbjct: 1395 EALEEGKKRFQ---KEIENLT-----------QQYEEKAAAYDKLEKTKNRLQQELDDLV 1440
Query: 517 LELEKTRDMLI----LQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRI 572
++L+ R ++ QRK + EE AD +R E E+ T+ L L
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500
Query: 573 KQLE 576
+ LE
Sbjct: 1501 EALE 1504
Score = 56.2 bits (134), Expect = 2e-07
Identities = 84/384 (21%), Positives = 166/384 (43%), Gaps = 36/384 (9%)
Query: 227 MASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHER 286
MA + +EE + E K + + + + + E+ + +L + +KLL ER
Sbjct: 955 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 1014
Query: 287 NASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVS-LKS 345
+ L A+ E ++A KN L HE+++ ++ E+R + +E+S++ + LK
Sbjct: 1015 ISDLTTNLAE--EEEKA------KNLTKLKNKHESMISEL-EVRLKKEEKSRQELEKLKR 1065
Query: 346 QLE-DVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE 404
+LE D S + + Q ++ +L+ + L ++L ++ D +Q + + + I E
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQ---LAKKEEELQAALARLDDEIAQKNNALKKIRE 1122
Query: 405 QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQ----------KHKQ 454
L+ +S LQ+ LD+E + K + + E LK E+ + L K +Q
Sbjct: 1123 -LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
Query: 455 EVELLQNA---ATISQPPDRQSEPATHPAVLQENT-QIEPSEPKNQEEKKLSQVLNELQV 510
EV +L+ A T S Q H ++E T Q+E + K Q L +
Sbjct: 1182 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1241
Query: 511 SHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNN 570
A L + + + ++K +EL++ + + + +K+ +L N
Sbjct: 1242 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL-------QN 1294
Query: 571 RIKQLEGILRSHDLPTSEQLKDVA 594
++ + G+L + + KDVA
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVA 1318
Score = 51.6 bits (122), Expect = 5e-06
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 36/294 (12%)
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
+ L + Q ++ LL + + I S + + + AE +E+ KA+SL LE
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYAD----ERDRAEAEAREKETKALSLARALE------ 1500
Query: 355 MTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQ---QVS 411
E E E+LE+ K+L + L+ S D + + S + Q+++ Q+
Sbjct: 1501 ----EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Query: 412 QLQDQLDAELEDKRKVLL-----------ELSREKAQNEDLKLEVTNILQKHKQEVELLQ 460
+L+D+L A + K ++ + +L QNE+ + ++ L +++ E+E +
Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER 1616
Query: 461 NAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELE 520
++ ++ E LQ ++ I+ E ++ +KL + + Q +
Sbjct: 1617 KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ----RELEDAR 1672
Query: 521 KTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQ 574
+RD + K N + LEA + + D ER + DL+ + +
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQED----LAAAERARKQADLEKEELAE 1722
Score = 50.8 bits (120), Expect = 8e-06
Identities = 81/384 (21%), Positives = 159/384 (41%), Gaps = 61/384 (15%)
Query: 250 NFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ 309
N + +++ A+ A L + +++ EL L E + +L +++E +L
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQDTQEL------LQEETRQKLNVSTKLRQLEEERNSLQD 1357
Query: 310 KNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEK 369
+ + A L + ++ L +L + KK S +E L+ K FQ+ +E+L +
Sbjct: 1358 QLDEEMEAKQN-LERHISTLNIQLSDSKKKLQDFASTVE---ALEEGKKRFQKEIENLTQ 1413
Query: 370 ERKLLNDNYDKL------LESMLDS------------SDSSSQPHWSNELIAEQ--LQQQ 409
+ + YDKL L+ LD S+ + ++L+AE+ + +
Sbjct: 1414 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1473
Query: 410 VSQLQDQLDAELEDKRKVLLELSR--EKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ 467
+ +D+ +AE +K L L+R E+A +LE TN + K + E +L+ + + +
Sbjct: 1474 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME-DLVSSKDDVGK 1532
Query: 468 PPDR--QSEPATHPAVLQENTQIEPSEPKNQ--EEKKLSQVLN----------------- 506
+S+ A + + TQ+E E + Q E+ KL +N
Sbjct: 1533 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 507 -------ELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLE 559
+LQ E ELE R L + +L+ + +AD+ + +E ++
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 560 RLTRLLDLKNNRIKQLEGILRSHD 583
+L +L + ++LE S D
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRD 1676
Score = 47.4 bits (111), Expect = 9e-05
Identities = 66/326 (20%), Positives = 138/326 (42%), Gaps = 73/326 (22%)
Query: 266 LRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAH--EALL 323
L +K +++ R ++ + + L TK + + + + L QK+ + + + L
Sbjct: 844 LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903
Query: 324 KQVNELRAELKEESKKAVSLKSQLEDV-SILQMTLKEFQERVEDLEKERKLLNDNYDKLL 382
+ EL AE +E + + K +LE++ ++ L+E ++R + L+ ERK K+
Sbjct: 904 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK-------KMA 956
Query: 383 ESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLK 442
+ MLD L++QL+ E ++K+ LE +A+ + L+
Sbjct: 957 QQMLD-------------------------LEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
Query: 443 LEV------TNILQKHKQEV-ELLQNAATISQPPDRQSEPAT-----HPAVLQE-NTQIE 489
E+ N L K ++ + E + + T + +++ T H +++ E +++
Sbjct: 992 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1051
Query: 490 PSEPKNQEEKKLSQVLN-----------ELQVSHAETTLELEKTRDMLILQRKINVCYQE 538
E QE +KL + L +LQ AE ++L K +E
Sbjct: 1052 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKK--------------EE 1097
Query: 539 ELEAMMTKADNDNRDHKEKLERLTRL 564
EL+A + + D++ L+++ L
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIREL 1123
Score = 45.4 bits (106), Expect = 3e-04
Identities = 65/335 (19%), Positives = 134/335 (40%), Gaps = 26/335 (7%)
Query: 260 AQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ---KNQGILS 316
A + A+LR + + + ++ L R+ + QL YET L+ K + + +
Sbjct: 1564 ATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAA 1623
Query: 317 AAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDL--------- 367
AA + L + +L + K QL LQ +K+FQ +ED
Sbjct: 1624 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRK---LQAQMKDFQRELEDARASRDEIFA 1680
Query: 368 -----EKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
EK+ K L + +L E + + + Q E +AE+L +S ++ L E
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG-RNALQDEKR 1739
Query: 423 DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVL 482
+ +L E + + +++ ++K Q+ E L N + +++E A
Sbjct: 1740 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1799
Query: 483 Q-ENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELE 541
Q + + + E + + K + L+ A+ ++E+ K ++L+
Sbjct: 1800 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1859
Query: 542 AMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
++ + + D ++ E+ + N R+KQL+
Sbjct: 1860 EILLQVE----DERKMAEQYKEQAEKGNARVKQLK 1890
Score = 42.4 bits (98), Expect = 0.003
Identities = 49/210 (23%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 254 RSSLECAQKAAELR-ASIKEKVELIRLK-KLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
R++L+ ++ E R A ++E++E + + + +R QL+ + QKN
Sbjct: 1731 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1790
Query: 312 QGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKER 371
+ +A + L +Q ELR++L E + AV K + ++ L+ + + +E+VE +E+
Sbjct: 1791 E----SARQQLERQNKELRSKL-HEMEGAVKSKFK-STIAALEAKIAQLEEQVEQEAREK 1844
Query: 372 ----KLLNDNYDKLLESMLDSSDSSSQPHWSNELI------AEQLQQQVSQLQDQLDAEL 421
K L KL E +L D E +QL++Q+ + +++
Sbjct: 1845 QAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRIN 1904
Query: 422 EDKRKVLLELSREKAQNEDLKLEVTNILQK 451
++RK+ EL NE + EV + K
Sbjct: 1905 ANRRKLQRELDEATESNEAMGREVNALKSK 1934
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 62.4 bits (150), Expect = 3e-09
Identities = 91/364 (25%), Positives = 145/364 (39%), Gaps = 59/364 (16%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNAS-----LVMTKAQLTEVQEAYET 306
E +L+ ELRA K + E+ LKK L E S M + V+E E
Sbjct: 1161 ELEDTLDSTATQQELRA--KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1218
Query: 307 L---------LQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDV----SIL 353
L L KN+ L + L ++ L +E K L++Q++++ S
Sbjct: 1219 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG 1278
Query: 354 QMTLKEFQERVEDLEKERK----LLNDNYDKLLESMLDSSDSSSQPHWSNELIAE----- 404
+ E ++V L+ E + +LN+ K ++ D + SSQ + EL+ E
Sbjct: 1279 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1338
Query: 405 --------QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEV 456
QL+++ + LQDQLD E+E K+ + +S Q D K + LQ V
Sbjct: 1339 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKK----LQDFASTV 1394
Query: 457 ELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETT 516
E L+ Q ++ E T + E K KL + N LQ +
Sbjct: 1395 EALEEGKKRFQ---KEIENLT-----------QQYEEKAAAYDKLEKTKNRLQQELDDLV 1440
Query: 517 LELEKTRDMLI----LQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRI 572
++L+ R ++ QRK + EE AD +R E E+ T+ L L
Sbjct: 1441 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1500
Query: 573 KQLE 576
+ LE
Sbjct: 1501 EALE 1504
Score = 56.2 bits (134), Expect = 2e-07
Identities = 84/384 (21%), Positives = 166/384 (43%), Gaps = 36/384 (9%)
Query: 227 MASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHER 286
MA + +EE + E K + + + + + E+ + +L + +KLL ER
Sbjct: 955 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 1014
Query: 287 NASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVS-LKS 345
+ L A+ E ++A KN L HE+++ ++ E+R + +E+S++ + LK
Sbjct: 1015 ISDLTTNLAE--EEEKA------KNLTKLKNKHESMISEL-EVRLKKEEKSRQELEKLKR 1065
Query: 346 QLE-DVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE 404
+LE D S + + Q ++ +L+ + L ++L ++ D +Q + + + I E
Sbjct: 1066 KLEGDASDFHEQIADLQAQIAELKMQ---LAKKEEELQAALARLDDEIAQKNNALKKIRE 1122
Query: 405 QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQ----------KHKQ 454
L+ +S LQ+ LD+E + K + + E LK E+ + L K +Q
Sbjct: 1123 -LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
Query: 455 EVELLQNA---ATISQPPDRQSEPATHPAVLQENT-QIEPSEPKNQEEKKLSQVLNELQV 510
EV +L+ A T S Q H ++E T Q+E + K Q L +
Sbjct: 1182 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1241
Query: 511 SHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNN 570
A L + + + ++K +EL++ + + + +K+ +L N
Sbjct: 1242 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL-------QN 1294
Query: 571 RIKQLEGILRSHDLPTSEQLKDVA 594
++ + G+L + + KDVA
Sbjct: 1295 EVESVTGMLNEAEGKAIKLAKDVA 1318
Score = 51.6 bits (122), Expect = 5e-06
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 36/294 (12%)
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
+ L + Q ++ LL + + I S + + + AE +E+ KA+SL LE
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYAD----ERDRAEAEAREKETKALSLARALE------ 1500
Query: 355 MTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQ---QVS 411
E E E+LE+ K+L + L+ S D + + S + Q+++ Q+
Sbjct: 1501 ----EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1556
Query: 412 QLQDQLDAELEDKRKVLL-----------ELSREKAQNEDLKLEVTNILQKHKQEVELLQ 460
+L+D+L A + K ++ + +L QNE+ + ++ L +++ E+E +
Sbjct: 1557 ELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER 1616
Query: 461 NAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELE 520
++ ++ E LQ ++ I+ E ++ +KL + + Q +
Sbjct: 1617 KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ----RELEDAR 1672
Query: 521 KTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQ 574
+RD + K N + LEA + + D ER + DL+ + +
Sbjct: 1673 ASRDEIFATAKENEKKAKSLEADLMQLQED----LAAAERARKQADLEKEELAE 1722
Score = 50.8 bits (120), Expect = 8e-06
Identities = 81/384 (21%), Positives = 159/384 (41%), Gaps = 61/384 (15%)
Query: 250 NFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ 309
N + +++ A+ A L + +++ EL L E + +L +++E +L
Sbjct: 1304 NEAEGKAIKLAKDVASLSSQLQDTQEL------LQEETRQKLNVSTKLRQLEEERNSLQD 1357
Query: 310 KNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEK 369
+ + A L + ++ L +L + KK S +E L+ K FQ+ +E+L +
Sbjct: 1358 QLDEEMEAKQN-LERHISTLNIQLSDSKKKLQDFASTVE---ALEEGKKRFQKEIENLTQ 1413
Query: 370 ERKLLNDNYDKL------LESMLDS------------SDSSSQPHWSNELIAEQ--LQQQ 409
+ + YDKL L+ LD S+ + ++L+AE+ + +
Sbjct: 1414 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1473
Query: 410 VSQLQDQLDAELEDKRKVLLELSR--EKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ 467
+ +D+ +AE +K L L+R E+A +LE TN + K + E +L+ + + +
Sbjct: 1474 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME-DLVSSKDDVGK 1532
Query: 468 PPDR--QSEPATHPAVLQENTQIEPSEPKNQ--EEKKLSQVLN----------------- 506
+S+ A + + TQ+E E + Q E+ KL +N
Sbjct: 1533 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 507 -------ELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLE 559
+LQ E ELE R L + +L+ + +AD+ + +E ++
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 560 RLTRLLDLKNNRIKQLEGILRSHD 583
+L +L + ++LE S D
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRD 1676
Score = 47.4 bits (111), Expect = 9e-05
Identities = 66/326 (20%), Positives = 138/326 (42%), Gaps = 73/326 (22%)
Query: 266 LRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAH--EALL 323
L +K +++ R ++ + + L TK + + + + L QK+ + + + L
Sbjct: 844 LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903
Query: 324 KQVNELRAELKEESKKAVSLKSQLEDV-SILQMTLKEFQERVEDLEKERKLLNDNYDKLL 382
+ EL AE +E + + K +LE++ ++ L+E ++R + L+ ERK K+
Sbjct: 904 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK-------KMA 956
Query: 383 ESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLK 442
+ MLD L++QL+ E ++K+ LE +A+ + L+
Sbjct: 957 QQMLD-------------------------LEEQLEEEEAARQKLQLEKVTAEAKIKKLE 991
Query: 443 LEV------TNILQKHKQEV-ELLQNAATISQPPDRQSEPAT-----HPAVLQE-NTQIE 489
E+ N L K ++ + E + + T + +++ T H +++ E +++
Sbjct: 992 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1051
Query: 490 PSEPKNQEEKKLSQVLN-----------ELQVSHAETTLELEKTRDMLILQRKINVCYQE 538
E QE +KL + L +LQ AE ++L K +E
Sbjct: 1052 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKK--------------EE 1097
Query: 539 ELEAMMTKADNDNRDHKEKLERLTRL 564
EL+A + + D++ L+++ L
Sbjct: 1098 ELQAALARLDDEIAQKNNALKKIREL 1123
Score = 45.4 bits (106), Expect = 3e-04
Identities = 65/335 (19%), Positives = 134/335 (40%), Gaps = 26/335 (7%)
Query: 260 AQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ---KNQGILS 316
A + A+LR + + + ++ L R+ + QL YET L+ K + + +
Sbjct: 1564 ATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAA 1623
Query: 317 AAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDL--------- 367
AA + L + +L + K QL LQ +K+FQ +ED
Sbjct: 1624 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRK---LQAQMKDFQRELEDARASRDEIFA 1680
Query: 368 -----EKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
EK+ K L + +L E + + + Q E +AE+L +S ++ L E
Sbjct: 1681 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG-RNALQDEKR 1739
Query: 423 DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVL 482
+ +L E + + +++ ++K Q+ E L N + +++E A
Sbjct: 1740 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1799
Query: 483 Q-ENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELE 541
Q + + + E + + K + L+ A+ ++E+ K ++L+
Sbjct: 1800 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1859
Query: 542 AMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
++ + + D ++ E+ + N R+KQL+
Sbjct: 1860 EILLQVE----DERKMAEQYKEQAEKGNARVKQLK 1890
Score = 42.4 bits (98), Expect = 0.003
Identities = 49/210 (23%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 254 RSSLECAQKAAELR-ASIKEKVELIRLK-KLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
R++L+ ++ E R A ++E++E + + + +R QL+ + QKN
Sbjct: 1731 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1790
Query: 312 QGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKER 371
+ +A + L +Q ELR++L E + AV K + ++ L+ + + +E+VE +E+
Sbjct: 1791 E----SARQQLERQNKELRSKL-HEMEGAVKSKFK-STIAALEAKIAQLEEQVEQEAREK 1844
Query: 372 ----KLLNDNYDKLLESMLDSSDSSSQPHWSNELI------AEQLQQQVSQLQDQLDAEL 421
K L KL E +L D E +QL++Q+ + +++
Sbjct: 1845 QAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRIN 1904
Query: 422 EDKRKVLLELSREKAQNEDLKLEVTNILQK 451
++RK+ EL NE + EV + K
Sbjct: 1905 ANRRKLQRELDEATESNEAMGREVNALKSK 1934
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 62.4 bits (150), Expect = 3e-09
Identities = 91/364 (25%), Positives = 145/364 (39%), Gaps = 59/364 (16%)
Query: 252 EQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNAS-----LVMTKAQLTEVQEAYET 306
E +L+ ELRA K + E+ LKK L E S M + V+E E
Sbjct: 1154 ELEDTLDSTATQQELRA--KREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 1211
Query: 307 L---------LQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDV----SIL 353
L L KN+ L + L ++ L +E K L++Q++++ S
Sbjct: 1212 LEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDG 1271
Query: 354 QMTLKEFQERVEDLEKERK----LLNDNYDKLLESMLDSSDSSSQPHWSNELIAE----- 404
+ E ++V L+ E + +LN+ K ++ D + SSQ + EL+ E
Sbjct: 1272 ERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQK 1331
Query: 405 --------QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEV 456
QL+++ + LQDQLD E+E K+ + +S Q D K + LQ V
Sbjct: 1332 LNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKK----LQDFASTV 1387
Query: 457 ELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETT 516
E L+ Q ++ E T + E K KL + N LQ +
Sbjct: 1388 EALEEGKKRFQ---KEIENLT-----------QQYEEKAAAYDKLEKTKNRLQQELDDLV 1433
Query: 517 LELEKTRDMLI----LQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRI 572
++L+ R ++ QRK + EE AD +R E E+ T+ L L
Sbjct: 1434 VDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALE 1493
Query: 573 KQLE 576
+ LE
Sbjct: 1494 EALE 1497
Score = 56.2 bits (134), Expect = 2e-07
Identities = 84/384 (21%), Positives = 166/384 (43%), Gaps = 36/384 (9%)
Query: 227 MASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHER 286
MA + +EE + E K + + + + + E+ + +L + +KLL ER
Sbjct: 948 MAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEER 1007
Query: 287 NASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVS-LKS 345
+ L A+ E ++A KN L HE+++ ++ E+R + +E+S++ + LK
Sbjct: 1008 ISDLTTNLAE--EEEKA------KNLTKLKNKHESMISEL-EVRLKKEEKSRQELEKLKR 1058
Query: 346 QLE-DVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAE 404
+LE D S + + Q ++ +L+ + L ++L ++ D +Q + + + I E
Sbjct: 1059 KLEGDASDFHEQIADLQAQIAELKMQ---LAKKEEELQAALARLDDEIAQKNNALKKIRE 1115
Query: 405 QLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQ----------KHKQ 454
L+ +S LQ+ LD+E + K + + E LK E+ + L K +Q
Sbjct: 1116 -LEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Query: 455 EVELLQNA---ATISQPPDRQSEPATHPAVLQENT-QIEPSEPKNQEEKKLSQVLNELQV 510
EV +L+ A T S Q H ++E T Q+E + K Q L +
Sbjct: 1175 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1234
Query: 511 SHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNN 570
A L + + + ++K +EL++ + + + +K+ +L N
Sbjct: 1235 DLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKL-------QN 1287
Query: 571 RIKQLEGILRSHDLPTSEQLKDVA 594
++ + G+L + + KDVA
Sbjct: 1288 EVESVTGMLNEAEGKAIKLAKDVA 1311
Score = 51.6 bits (122), Expect = 5e-06
Identities = 60/294 (20%), Positives = 123/294 (41%), Gaps = 36/294 (12%)
Query: 295 AQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
+ L + Q ++ LL + + I S + + + AE +E+ KA+SL LE
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYAD----ERDRAEAEAREKETKALSLARALE------ 1493
Query: 355 MTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQ---QVS 411
E E E+LE+ K+L + L+ S D + + S + Q+++ Q+
Sbjct: 1494 ----EALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLE 1549
Query: 412 QLQDQLDAELEDKRKVLL-----------ELSREKAQNEDLKLEVTNILQKHKQEVELLQ 460
+L+D+L A + K ++ + +L QNE+ + ++ L +++ E+E +
Sbjct: 1550 ELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDER 1609
Query: 461 NAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELE 520
++ ++ E LQ ++ I+ E ++ +KL + + Q +
Sbjct: 1610 KQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQ----RELEDAR 1665
Query: 521 KTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQ 574
+RD + K N + LEA + + D ER + DL+ + +
Sbjct: 1666 ASRDEIFATAKENEKKAKSLEADLMQLQED----LAAAERARKQADLEKEELAE 1715
Score = 50.8 bits (120), Expect = 8e-06
Identities = 81/384 (21%), Positives = 159/384 (41%), Gaps = 61/384 (15%)
Query: 250 NFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ 309
N + +++ A+ A L + +++ EL L E + +L +++E +L
Sbjct: 1297 NEAEGKAIKLAKDVASLSSQLQDTQEL------LQEETRQKLNVSTKLRQLEEERNSLQD 1350
Query: 310 KNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEK 369
+ + A L + ++ L +L + KK S +E L+ K FQ+ +E+L +
Sbjct: 1351 QLDEEMEAKQN-LERHISTLNIQLSDSKKKLQDFASTVE---ALEEGKKRFQKEIENLTQ 1406
Query: 370 ERKLLNDNYDKL------LESMLDS------------SDSSSQPHWSNELIAEQ--LQQQ 409
+ + YDKL L+ LD S+ + ++L+AE+ + +
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
Query: 410 VSQLQDQLDAELEDKRKVLLELSR--EKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ 467
+ +D+ +AE +K L L+R E+A +LE TN + K + E +L+ + + +
Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME-DLVSSKDDVGK 1525
Query: 468 PPDR--QSEPATHPAVLQENTQIEPSEPKNQ--EEKKLSQVLN----------------- 506
+S+ A + + TQ+E E + Q E+ KL +N
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 507 -------ELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLE 559
+LQ E ELE R L + +L+ + +AD+ + +E ++
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 560 RLTRLLDLKNNRIKQLEGILRSHD 583
+L +L + ++LE S D
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRD 1669
Score = 47.4 bits (111), Expect = 9e-05
Identities = 66/326 (20%), Positives = 138/326 (42%), Gaps = 73/326 (22%)
Query: 266 LRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAH--EALL 323
L +K +++ R ++ + + L TK + + + + L QK+ + + + L
Sbjct: 837 LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896
Query: 324 KQVNELRAELKEESKKAVSLKSQLEDV-SILQMTLKEFQERVEDLEKERKLLNDNYDKLL 382
+ EL AE +E + + K +LE++ ++ L+E ++R + L+ ERK K+
Sbjct: 897 QAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERK-------KMA 949
Query: 383 ESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLK 442
+ MLD L++QL+ E ++K+ LE +A+ + L+
Sbjct: 950 QQMLD-------------------------LEEQLEEEEAARQKLQLEKVTAEAKIKKLE 984
Query: 443 LEV------TNILQKHKQEV-ELLQNAATISQPPDRQSEPAT-----HPAVLQE-NTQIE 489
E+ N L K ++ + E + + T + +++ T H +++ E +++
Sbjct: 985 DEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLK 1044
Query: 490 PSEPKNQEEKKLSQVLN-----------ELQVSHAETTLELEKTRDMLILQRKINVCYQE 538
E QE +KL + L +LQ AE ++L K +E
Sbjct: 1045 KEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKK--------------EE 1090
Query: 539 ELEAMMTKADNDNRDHKEKLERLTRL 564
EL+A + + D++ L+++ L
Sbjct: 1091 ELQAALARLDDEIAQKNNALKKIREL 1116
Score = 45.4 bits (106), Expect = 3e-04
Identities = 65/335 (19%), Positives = 134/335 (40%), Gaps = 26/335 (7%)
Query: 260 AQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQ---KNQGILS 316
A + A+LR + + + ++ L R+ + QL YET L+ K + + +
Sbjct: 1557 ATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAA 1616
Query: 317 AAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDL--------- 367
AA + L + +L + K QL LQ +K+FQ +ED
Sbjct: 1617 AAKKKLEGDLKDLELQADSAIKGREEAIKQLRK---LQAQMKDFQRELEDARASRDEIFA 1673
Query: 368 -----EKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELE 422
EK+ K L + +L E + + + Q E +AE+L +S ++ L E
Sbjct: 1674 TAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG-RNALQDEKR 1732
Query: 423 DKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVL 482
+ +L E + + +++ ++K Q+ E L N + +++E A
Sbjct: 1733 RLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLER 1792
Query: 483 Q-ENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELE 541
Q + + + E + + K + L+ A+ ++E+ K ++L+
Sbjct: 1793 QNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLK 1852
Query: 542 AMMTKADNDNRDHKEKLERLTRLLDLKNNRIKQLE 576
++ + + D ++ E+ + N R+KQL+
Sbjct: 1853 EILLQVE----DERKMAEQYKEQAEKGNARVKQLK 1883
Score = 42.4 bits (98), Expect = 0.003
Identities = 49/210 (23%), Positives = 95/210 (45%), Gaps = 18/210 (8%)
Query: 254 RSSLECAQKAAELR-ASIKEKVELIRLK-KLLHERNASLVMTKAQLTEVQEAYETLLQKN 311
R++L+ ++ E R A ++E++E + + + +R QL+ + QKN
Sbjct: 1724 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1783
Query: 312 QGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKER 371
+ +A + L +Q ELR++L E + AV K + ++ L+ + + +E+VE +E+
Sbjct: 1784 E----SARQQLERQNKELRSKL-HEMEGAVKSKFK-STIAALEAKIAQLEEQVEQEAREK 1837
Query: 372 ----KLLNDNYDKLLESMLDSSDSSSQPHWSNELI------AEQLQQQVSQLQDQLDAEL 421
K L KL E +L D E +QL++Q+ + +++
Sbjct: 1838 QAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRIN 1897
Query: 422 EDKRKVLLELSREKAQNEDLKLEVTNILQK 451
++RK+ EL NE + EV + K
Sbjct: 1898 ANRRKLQRELDEATESNEAMGREVNALKSK 1927
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 61.6 bits (148), Expect = 5e-09
Identities = 79/349 (22%), Positives = 148/349 (42%), Gaps = 29/349 (8%)
Query: 242 EKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQ 301
E+M + FE+ E Q EL +++ + RL K L E S L E
Sbjct: 279 EEMVKEKNLFEE----ELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL 334
Query: 302 EAYETLLQKNQG-------ILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
+ E L+K+ +L ++++++ + ++ A+ ES KA++ S++ED+ +
Sbjct: 335 KGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQF--ESYKALTA-SEIEDLKLEN 391
Query: 355 MTLKEFQERV----EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQV 410
+L+E + ED++ + + + + +LD S+ + I Q++
Sbjct: 392 SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI 451
Query: 411 SQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ--- 467
+ LQ+QL + ED RK L + KA+ E+ E+T + K + E L N Q
Sbjct: 452 TDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQL 511
Query: 468 ---PPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLN---ELQVSHAETTLELEK 521
++Q+ H A ++ +I S K + L Q + +L+ +++ E+ K
Sbjct: 512 DAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSK 571
Query: 522 TRDMLILQRKINVCYQEELEAMM--TKADNDNRDHKEKLERLTRLLDLK 568
R L +++ QEEL ++ D H E E LK
Sbjct: 572 LRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLK 620
Score = 48.9 bits (115), Expect = 3e-05
Identities = 88/379 (23%), Positives = 151/379 (39%), Gaps = 69/379 (18%)
Query: 244 MWPKDENFE------QRSSLECAQKAAEL--------RASIKEKVELIRLKKLLHERNAS 289
M K E E QRS E K A+L + I EK E +L + + E + +
Sbjct: 98 MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCA 157
Query: 290 LVMTKAQLTEVQEAYETLLQKNQGILSAAHE------ALLKQVNELRAE---LKEESKKA 340
+ ++ + E L +KN ILS L KQV +L + L++E +
Sbjct: 158 SDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDH 217
Query: 341 VSLKSQ------LEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQ 394
V+ + E ++ Q + E QER + +KE ++ D LL+ + S S Q
Sbjct: 218 VNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQI-----DSLLQQEKELSSSLHQ 272
Query: 395 PHWS--------NELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSRE-KAQNEDLKL-- 443
S L E+L+Q + +L D+L + E +++ +L E K++ E+LKL
Sbjct: 273 KLCSFQEEMVKEKNLFEEELKQTLDEL-DKLQQKEEQAERLVKQLEEEAKSRAEELKLLE 331
Query: 444 --------EVTNILQKHKQEVELLQNA--ATISQPPDRQSEPATHPAVLQENTQIEPSEP 493
E+ H Q LLQ + + D ++ ++ A+ + E
Sbjct: 332 EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN 391
Query: 494 KNQEEKKLSQVLNELQVSH---AETTLELEKTRDMLILQRK----------INVCYQEEL 540
+ +EK N V H A + E R +L LQ K I V + +++
Sbjct: 392 SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI 451
Query: 541 EAMMTKADNDNRDHKEKLE 559
+ + D +++LE
Sbjct: 452 TDLQNQLKQQEEDFRKQLE 470
Score = 47.8 bits (112), Expect = 7e-05
Identities = 56/257 (21%), Positives = 128/257 (49%), Gaps = 18/257 (7%)
Query: 277 IRLKKLLHERNASL--VMTKAQLTEVQ-EAYETLLQKNQGILSAAHEALLKQVNELRAEL 333
+ L KL ++R + +M K + E++ + + L+++QG + A E L + + + +
Sbjct: 82 LELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKI-AQLEGKLVSIEKEKIDE 140
Query: 334 KEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDS----S 389
K E++K L +E++S +++++ + LE+ K ND L +S+ ++ S
Sbjct: 141 KSETEK---LLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILS 197
Query: 390 DSSSQPHWSNELIAEQLQQQVSQLQDQ---LDAELED-KRKVLLELS-REKAQNEDLKLE 444
+ +L+ ++ + V++ ++ L+AE+++ K+K +LE REK Q ++L+++
Sbjct: 198 KQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID 257
Query: 445 VTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQV 504
++LQ+ K+ L Q + + + Q +++ + K ++ ++L +
Sbjct: 258 --SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQ 315
Query: 505 LNELQVSHAETTLELEK 521
L E S AE LE+
Sbjct: 316 LEEEAKSRAEELKLLEE 332
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 61.6 bits (148), Expect = 5e-09
Identities = 79/349 (22%), Positives = 148/349 (42%), Gaps = 29/349 (8%)
Query: 242 EKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQ 301
E+M + FE+ E Q EL +++ + RL K L E S L E
Sbjct: 366 EEMVKEKNLFEE----ELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL 421
Query: 302 EAYETLLQKNQG-------ILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
+ E L+K+ +L ++++++ + ++ A+ ES KA++ S++ED+ +
Sbjct: 422 KGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQF--ESYKALTA-SEIEDLKLEN 478
Query: 355 MTLKEFQERV----EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQV 410
+L+E + ED++ + + + + +LD S+ + I Q++
Sbjct: 479 SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI 538
Query: 411 SQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ--- 467
+ LQ+QL + ED RK L + KA+ E+ E+T + K + E L N Q
Sbjct: 539 TDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQL 598
Query: 468 ---PPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLN---ELQVSHAETTLELEK 521
++Q+ H A ++ +I S K + L Q + +L+ +++ E+ K
Sbjct: 599 DAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSK 658
Query: 522 TRDMLILQRKINVCYQEELEAMM--TKADNDNRDHKEKLERLTRLLDLK 568
R L +++ QEEL ++ D H E E LK
Sbjct: 659 LRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLK 707
Score = 48.9 bits (115), Expect = 3e-05
Identities = 88/379 (23%), Positives = 151/379 (39%), Gaps = 69/379 (18%)
Query: 244 MWPKDENFE------QRSSLECAQKAAEL--------RASIKEKVELIRLKKLLHERNAS 289
M K E E QRS E K A+L + I EK E +L + + E + +
Sbjct: 185 MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCA 244
Query: 290 LVMTKAQLTEVQEAYETLLQKNQGILSAAHE------ALLKQVNELRAE---LKEESKKA 340
+ ++ + E L +KN ILS L KQV +L + L++E +
Sbjct: 245 SDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDH 304
Query: 341 VSLKSQ------LEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQ 394
V+ + E ++ Q + E QER + +KE ++ D LL+ + S S Q
Sbjct: 305 VNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQI-----DSLLQQEKELSSSLHQ 359
Query: 395 PHWS--------NELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSRE-KAQNEDLKL-- 443
S L E+L+Q + +L D+L + E +++ +L E K++ E+LKL
Sbjct: 360 KLCSFQEEMVKEKNLFEEELKQTLDEL-DKLQQKEEQAERLVKQLEEEAKSRAEELKLLE 418
Query: 444 --------EVTNILQKHKQEVELLQNA--ATISQPPDRQSEPATHPAVLQENTQIEPSEP 493
E+ H Q LLQ + + D ++ ++ A+ + E
Sbjct: 419 EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN 478
Query: 494 KNQEEKKLSQVLNELQVSH---AETTLELEKTRDMLILQRK----------INVCYQEEL 540
+ +EK N V H A + E R +L LQ K I V + +++
Sbjct: 479 SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI 538
Query: 541 EAMMTKADNDNRDHKEKLE 559
+ + D +++LE
Sbjct: 539 TDLQNQLKQQEEDFRKQLE 557
Score = 47.8 bits (112), Expect = 7e-05
Identities = 56/257 (21%), Positives = 128/257 (49%), Gaps = 18/257 (7%)
Query: 277 IRLKKLLHERNASL--VMTKAQLTEVQ-EAYETLLQKNQGILSAAHEALLKQVNELRAEL 333
+ L KL ++R + +M K + E++ + + L+++QG + A E L + + + +
Sbjct: 169 LELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKI-AQLEGKLVSIEKEKIDE 227
Query: 334 KEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDS----S 389
K E++K L +E++S +++++ + LE+ K ND L +S+ ++ S
Sbjct: 228 KSETEK---LLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILS 284
Query: 390 DSSSQPHWSNELIAEQLQQQVSQLQDQ---LDAELED-KRKVLLELS-REKAQNEDLKLE 444
+ +L+ ++ + V++ ++ L+AE+++ K+K +LE REK Q ++L+++
Sbjct: 285 KQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID 344
Query: 445 VTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQV 504
++LQ+ K+ L Q + + + Q +++ + K ++ ++L +
Sbjct: 345 --SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQ 402
Query: 505 LNELQVSHAETTLELEK 521
L E S AE LE+
Sbjct: 403 LEEEAKSRAEELKLLEE 419
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 61.6 bits (148), Expect = 5e-09
Identities = 79/349 (22%), Positives = 148/349 (42%), Gaps = 29/349 (8%)
Query: 242 EKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQ 301
E+M + FE+ E Q EL +++ + RL K L E S L E
Sbjct: 350 EEMVKEKNLFEE----ELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL 405
Query: 302 EAYETLLQKNQG-------ILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
+ E L+K+ +L ++++++ + ++ A+ ES KA++ S++ED+ +
Sbjct: 406 KGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQF--ESYKALTA-SEIEDLKLEN 462
Query: 355 MTLKEFQERV----EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQV 410
+L+E + ED++ + + + + +LD S+ + I Q++
Sbjct: 463 SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI 522
Query: 411 SQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ--- 467
+ LQ+QL + ED RK L + KA+ E+ E+T + K + E L N Q
Sbjct: 523 TDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQL 582
Query: 468 ---PPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLN---ELQVSHAETTLELEK 521
++Q+ H A ++ +I S K + L Q + +L+ +++ E+ K
Sbjct: 583 DAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSK 642
Query: 522 TRDMLILQRKINVCYQEELEAMM--TKADNDNRDHKEKLERLTRLLDLK 568
R L +++ QEEL ++ D H E E LK
Sbjct: 643 LRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLK 691
Score = 48.9 bits (115), Expect = 3e-05
Identities = 88/379 (23%), Positives = 151/379 (39%), Gaps = 69/379 (18%)
Query: 244 MWPKDENFE------QRSSLECAQKAAEL--------RASIKEKVELIRLKKLLHERNAS 289
M K E E QRS E K A+L + I EK E +L + + E + +
Sbjct: 169 MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCA 228
Query: 290 LVMTKAQLTEVQEAYETLLQKNQGILSAAHE------ALLKQVNELRAE---LKEESKKA 340
+ ++ + E L +KN ILS L KQV +L + L++E +
Sbjct: 229 SDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDH 288
Query: 341 VSLKSQ------LEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQ 394
V+ + E ++ Q + E QER + +KE ++ D LL+ + S S Q
Sbjct: 289 VNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQI-----DSLLQQEKELSSSLHQ 343
Query: 395 PHWS--------NELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSRE-KAQNEDLKL-- 443
S L E+L+Q + +L D+L + E +++ +L E K++ E+LKL
Sbjct: 344 KLCSFQEEMVKEKNLFEEELKQTLDEL-DKLQQKEEQAERLVKQLEEEAKSRAEELKLLE 402
Query: 444 --------EVTNILQKHKQEVELLQNA--ATISQPPDRQSEPATHPAVLQENTQIEPSEP 493
E+ H Q LLQ + + D ++ ++ A+ + E
Sbjct: 403 EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN 462
Query: 494 KNQEEKKLSQVLNELQVSH---AETTLELEKTRDMLILQRK----------INVCYQEEL 540
+ +EK N V H A + E R +L LQ K I V + +++
Sbjct: 463 SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI 522
Query: 541 EAMMTKADNDNRDHKEKLE 559
+ + D +++LE
Sbjct: 523 TDLQNQLKQQEEDFRKQLE 541
Score = 47.8 bits (112), Expect = 7e-05
Identities = 56/257 (21%), Positives = 128/257 (49%), Gaps = 18/257 (7%)
Query: 277 IRLKKLLHERNASL--VMTKAQLTEVQ-EAYETLLQKNQGILSAAHEALLKQVNELRAEL 333
+ L KL ++R + +M K + E++ + + L+++QG + A E L + + + +
Sbjct: 153 LELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKI-AQLEGKLVSIEKEKIDE 211
Query: 334 KEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDS----S 389
K E++K L +E++S +++++ + LE+ K ND L +S+ ++ S
Sbjct: 212 KSETEK---LLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILS 268
Query: 390 DSSSQPHWSNELIAEQLQQQVSQLQDQ---LDAELED-KRKVLLELS-REKAQNEDLKLE 444
+ +L+ ++ + V++ ++ L+AE+++ K+K +LE REK Q ++L+++
Sbjct: 269 KQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID 328
Query: 445 VTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQV 504
++LQ+ K+ L Q + + + Q +++ + K ++ ++L +
Sbjct: 329 --SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQ 386
Query: 505 LNELQVSHAETTLELEK 521
L E S AE LE+
Sbjct: 387 LEEEAKSRAEELKLLEE 403
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 61.6 bits (148), Expect = 5e-09
Identities = 79/349 (22%), Positives = 148/349 (42%), Gaps = 29/349 (8%)
Query: 242 EKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQ 301
E+M + FE+ E Q EL +++ + RL K L E S L E
Sbjct: 365 EEMVKEKNLFEE----ELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKL 420
Query: 302 EAYETLLQKNQG-------ILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQ 354
+ E L+K+ +L ++++++ + ++ A+ ES KA++ S++ED+ +
Sbjct: 421 KGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQF--ESYKALTA-SEIEDLKLEN 477
Query: 355 MTLKEFQERV----EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQV 410
+L+E + ED++ + + + + +LD S+ + I Q++
Sbjct: 478 SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI 537
Query: 411 SQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQ--- 467
+ LQ+QL + ED RK L + KA+ E+ E+T + K + E L N Q
Sbjct: 538 TDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQL 597
Query: 468 ---PPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLN---ELQVSHAETTLELEK 521
++Q+ H A ++ +I S K + L Q + +L+ +++ E+ K
Sbjct: 598 DAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSK 657
Query: 522 TRDMLILQRKINVCYQEELEAMM--TKADNDNRDHKEKLERLTRLLDLK 568
R L +++ QEEL ++ D H E E LK
Sbjct: 658 LRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLK 706
Score = 48.9 bits (115), Expect = 3e-05
Identities = 88/379 (23%), Positives = 151/379 (39%), Gaps = 69/379 (18%)
Query: 244 MWPKDENFE------QRSSLECAQKAAEL--------RASIKEKVELIRLKKLLHERNAS 289
M K E E QRS E K A+L + I EK E +L + + E + +
Sbjct: 184 MMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCA 243
Query: 290 LVMTKAQLTEVQEAYETLLQKNQGILSAAHE------ALLKQVNELRAE---LKEESKKA 340
+ ++ + E L +KN ILS L KQV +L + L++E +
Sbjct: 244 SDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDH 303
Query: 341 VSLKSQ------LEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQ 394
V+ + E ++ Q + E QER + +KE ++ D LL+ + S S Q
Sbjct: 304 VNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQI-----DSLLQQEKELSSSLHQ 358
Query: 395 PHWS--------NELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSRE-KAQNEDLKL-- 443
S L E+L+Q + +L D+L + E +++ +L E K++ E+LKL
Sbjct: 359 KLCSFQEEMVKEKNLFEEELKQTLDEL-DKLQQKEEQAERLVKQLEEEAKSRAEELKLLE 417
Query: 444 --------EVTNILQKHKQEVELLQNA--ATISQPPDRQSEPATHPAVLQENTQIEPSEP 493
E+ H Q LLQ + + D ++ ++ A+ + E
Sbjct: 418 EKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLEN 477
Query: 494 KNQEEKKLSQVLNELQVSH---AETTLELEKTRDMLILQRK----------INVCYQEEL 540
+ +EK N V H A + E R +L LQ K I V + +++
Sbjct: 478 SSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI 537
Query: 541 EAMMTKADNDNRDHKEKLE 559
+ + D +++LE
Sbjct: 538 TDLQNQLKQQEEDFRKQLE 556
Score = 47.8 bits (112), Expect = 7e-05
Identities = 56/257 (21%), Positives = 128/257 (49%), Gaps = 18/257 (7%)
Query: 277 IRLKKLLHERNASL--VMTKAQLTEVQ-EAYETLLQKNQGILSAAHEALLKQVNELRAEL 333
+ L KL ++R + +M K + E++ + + L+++QG + A E L + + + +
Sbjct: 168 LELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKI-AQLEGKLVSIEKEKIDE 226
Query: 334 KEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDS----S 389
K E++K L +E++S +++++ + LE+ K ND L +S+ ++ S
Sbjct: 227 KSETEK---LLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILS 283
Query: 390 DSSSQPHWSNELIAEQLQQQVSQLQDQ---LDAELED-KRKVLLELS-REKAQNEDLKLE 444
+ +L+ ++ + V++ ++ L+AE+++ K+K +LE REK Q ++L+++
Sbjct: 284 KQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQID 343
Query: 445 VTNILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQV 504
++LQ+ K+ L Q + + + Q +++ + K ++ ++L +
Sbjct: 344 --SLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQ 401
Query: 505 LNELQVSHAETTLELEK 521
L E S AE LE+
Sbjct: 402 LEEEAKSRAEELKLLEE 418
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 61.6 bits (148), Expect = 5e-09
Identities = 94/392 (23%), Positives = 169/392 (43%), Gaps = 71/392 (18%)
Query: 254 RSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQG 313
R S + A L AS+++ E RL+ L SL TK L V+ E Q+++
Sbjct: 560 RKSEQGLGSAEGLIASLQDSQE--RLQNELDLTKDSLKETKDALLNVEGELEQERQQHEE 617
Query: 314 ILSA------------AHEALLKQVNELRAEL-----------KEESKKAVSLKSQLEDV 350
++A AH+ +K LR E +E+ K A+S QL+D
Sbjct: 618 TIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDR 677
Query: 351 SILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQV 410
+Q++VEDL + LL N LE L S +S Q QLQ Q
Sbjct: 678 E-KNAARDSWQKKVEDLLNQISLLKQN----LEIQLSQSQTSLQ----------QLQAQF 722
Query: 411 SQLQDQLDAELED-------------KRKVLLELSREKAQNEDLKLEVTNILQKHKQEVE 457
+Q + +L ELE+ + VL + E+ + ++ + ++ QKH E++
Sbjct: 723 TQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQ 782
Query: 458 LLQNAATISQPPDR---QSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSH-- 512
L++A S R + E T L++ + + +++ + + ++ L+ +H
Sbjct: 783 SLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQ 842
Query: 513 --AETTLELEKTRDMLILQRKINVC----YQEEL---EAMMTKADNDNRDHKEKLERLTR 563
A +ELE++ D+ Q K ++C QEEL E +++ D + + E + LT+
Sbjct: 843 ELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTK 902
Query: 564 LLDLKNNRIKQLEG----ILRSHDLPTSEQLK 591
L+ K I ++ +R H+ +++L+
Sbjct: 903 ELEFKGKEILRIRSESNQQIRLHEQDLNKRLE 934
Score = 55.1 bits (131), Expect = 4e-07
Identities = 67/333 (20%), Positives = 142/333 (42%), Gaps = 27/333 (8%)
Query: 261 QKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGI---LSA 317
Q + S+ +K + ++ + E N ++ + QL + +E LL K++ + L+A
Sbjct: 310 QMVQDEAGSLLDKCQKLQTALAIAENNVQVL--QKQLDDAKEGEMALLSKHKEVESELAA 367
Query: 318 AHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDN 377
A E L +Q ++L + + +Q + L+ ER+ LE+ER L
Sbjct: 368 ARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSK 427
Query: 378 YDKL----------LESMLDSSDSSSQPHWSNEL--IAEQLQQQVSQLQDQLDAELED-- 423
L LE ++ + + Q ++ EL + +L+++V+QL + LE+
Sbjct: 428 TQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELA 487
Query: 424 -KRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHP--A 480
K + +E A + KL++ Q +K ++ L ++ + Q + E
Sbjct: 488 WKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNT 547
Query: 481 VLQENTQIEPSEPKNQEEKKLSQ-VLNELQVSHAETTLELEKTRDMLILQRKINVCYQEE 539
QE ++ K+++ ++ ++ LQ S EL+ T+D L + + + E
Sbjct: 548 ANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGE 607
Query: 540 LEAMMTKADND----NRDHKEKLERLTRLLDLK 568
LE + + + K K++++ L++K
Sbjct: 608 LEQERQQHEETIAAMKEEEKLKVDKMAHDLEIK 640
Score = 47.8 bits (112), Expect = 7e-05
Identities = 91/453 (20%), Positives = 182/453 (40%), Gaps = 60/453 (13%)
Query: 176 SFKEHATNENRGEVASKPSEL-VSGSNSIISFSSVISMAKPIGLCMPNSAHIMASNTMQV 234
S+++H + + A P+ ++G + S + M+K I + I A NT
Sbjct: 7 SWQQHYYGGSAAKFAPSPATAQLAGHSMDYSQEMHLKMSKKIAQL---TKVIYALNTKN- 62
Query: 235 EEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTK 294
+E + + + E Q+ E +K + ++ + E+++L R ++L + K
Sbjct: 63 DEHESAIQALKDAHEEEIQQILAETREKILQYKSKVTEELDLRRKIQVLESSLEDHIKMK 122
Query: 295 AQLTEVQEAYETLLQKNQGILSAAH----EALLKQVNELRAELKEESKKAVSLKSQLEDV 350
Q EAY+ ++ Q A H + ++V E+R + +E+ + L+ Q E
Sbjct: 123 QQALTEFEAYKHRVEDMQLCAEAQHVQRIVTMSREVEEIRRKFEEKLRSFGQLQVQFEKD 182
Query: 351 SILQMT------LKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNEL--- 401
L + +E QE ++ + +N +K E L + S EL
Sbjct: 183 KRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEE--LHRMEVESLNKMLEELRLE 240
Query: 402 ---IAEQLQQQVSQLQDQLDAELEDKRKVLL----ELSREKAQNEDLKLE-------VTN 447
+ E + ++++ Q + EL+ ++ L L K + DL+ E +
Sbjct: 241 RKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRK 300
Query: 448 ILQKHKQEVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNE 507
+ K K E++++Q+ A D+ + T A+ + N Q+ + + +E +++
Sbjct: 301 TIGKLKTELQMVQDEA--GSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMA----- 353
Query: 508 LQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMMTKADNDNRDHKEKLERLTRLLDL 567
L H E EL R+ L Q++ ++ KA + ++ + + DL
Sbjct: 354 LLSKHKEVESELAAARERL----------QQQASDLVLKASHIGMLQATQMTQEVTIKDL 403
Query: 568 K------NNRIKQLE---GILRSHDLPTSEQLK 591
+ N R+ QLE LRS E+ K
Sbjct: 404 ESEKSRVNERLSQLEEERAFLRSKTQSLDEEQK 436
Score = 40.4 bits (93), Expect = 0.011
Identities = 68/334 (20%), Positives = 144/334 (43%), Gaps = 31/334 (9%)
Query: 232 MQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAE--------LRASIKEKVELIRLKKLL 283
+Q EE KS + ++ E+ ++ + QK E L+ +++ ++L + + L
Sbjct: 658 LQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLE--IQLSQSQTSL 715
Query: 284 HERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSL 343
+ A + +LT+ E E Q+ L AH + + E KE+ ++A+
Sbjct: 716 QQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTME----EEKEKEQRALEN 771
Query: 344 KSQLEDVSILQMTLKEFQERVE----DLEKERKLLNDNYDKLLESMLDS--SDSSSQPHW 397
Q + + LQ +E +E ++E+E + L + ++ML S S+ + Q
Sbjct: 772 HLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAA 831
Query: 398 SNELIAEQLQQQVSQLQDQLDAELEDKRKVLLE-LSREKAQNEDLKLEVTNILQKHKQEV 456
+ +L+ Q+++ + +L+ ++ R+ E + R E+L+ +I + K+
Sbjct: 832 AIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQ 891
Query: 457 ELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAE-- 514
L +N + +++ + + + + N QI E K+L + L+ + H
Sbjct: 892 HLHENISALTKELEFKGKEILR-IRSESNQQIRLHE--QDLNKRLEKELDVMTADHLREK 948
Query: 515 --TTLELEKTRDMLILQRKINVCYQEELEAMMTK 546
+ KT ++L ++IN Q LE M K
Sbjct: 949 NIMRADFNKTNELL---KEINAALQVSLEEMEEK 979
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 61.2 bits (147), Expect = 6e-09
Identities = 91/372 (24%), Positives = 160/372 (43%), Gaps = 67/372 (18%)
Query: 254 RSSLECAQKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQG 313
R S + A L AS+++ E RL+ L SL TK L V+ E Q+++
Sbjct: 440 RKSEQGLGSAEGLIASLQDSQE--RLQNELDLTKDSLKETKDALLNVEGELEQERQQHEE 497
Query: 314 ILSA------------AHEALLKQVNELRAEL-----------KEESKKAVSLKSQLEDV 350
++A AH+ +K LR E +E+ K A+S QL+D
Sbjct: 498 TIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDR 557
Query: 351 SILQMTLKEFQERVEDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQV 410
+Q++VEDL + LL N LE L S +S Q QLQ Q
Sbjct: 558 E-KNAARDSWQKKVEDLLNQISLLKQN----LEIQLSQSQTSLQ----------QLQAQF 602
Query: 411 SQLQDQLDAELED-------------KRKVLLELSREKAQNEDLKLEVTNILQKHKQEVE 457
+Q + +L ELE+ + VL + E+ + ++ + ++ QKH E++
Sbjct: 603 TQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHLQQKHSAELQ 662
Query: 458 LLQNAATISQPPDR---QSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSH-- 512
L++A S R + E T L++ + + +++ + + ++ L+ +H
Sbjct: 663 SLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAAAIDLLRHNHHQ 722
Query: 513 --AETTLELEKTRDMLILQRKINVC----YQEEL---EAMMTKADNDNRDHKEKLERLTR 563
A +ELE++ D+ Q K ++C QEEL E +++ D + + E + LT+
Sbjct: 723 ELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQHLHENISALTK 782
Query: 564 LLDLKNNRIKQL 575
L+ K I ++
Sbjct: 783 ELEFKGKEILRI 794
Score = 55.1 bits (131), Expect = 4e-07
Identities = 67/333 (20%), Positives = 142/333 (42%), Gaps = 27/333 (8%)
Query: 261 QKAAELRASIKEKVELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGI---LSA 317
Q + S+ +K + ++ + E N ++ + QL + +E LL K++ + L+A
Sbjct: 190 QMVQDEAGSLLDKCQKLQTALAIAENNVQVL--QKQLDDAKEGEMALLSKHKEVESELAA 247
Query: 318 AHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERVEDLEKERKLLNDN 377
A E L +Q ++L + + +Q + L+ ER+ LE+ER L
Sbjct: 248 ARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAFLRSK 307
Query: 378 YDKL----------LESMLDSSDSSSQPHWSNEL--IAEQLQQQVSQLQDQLDAELED-- 423
L LE ++ + + Q ++ EL + +L+++V+QL + LE+
Sbjct: 308 TQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTLEELA 367
Query: 424 -KRKVLLELSREKAQNEDLKLEVTNILQKHKQEVELLQNAATISQPPDRQSEPATHP--A 480
K + +E A + KL++ Q +K ++ L ++ + Q + E
Sbjct: 368 WKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNT 427
Query: 481 VLQENTQIEPSEPKNQEEKKLSQ-VLNELQVSHAETTLELEKTRDMLILQRKINVCYQEE 539
QE ++ K+++ ++ ++ LQ S EL+ T+D L + + + E
Sbjct: 428 ANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDALLNVEGE 487
Query: 540 LEAMMTKADND----NRDHKEKLERLTRLLDLK 568
LE + + + K K++++ L++K
Sbjct: 488 LEQERQQHEETIAAMKEEEKLKVDKMAHDLEIK 520
Score = 44.7 bits (104), Expect = 6e-04
Identities = 68/303 (22%), Positives = 129/303 (42%), Gaps = 62/303 (20%)
Query: 315 LSAAHEALLKQVNELRAELKEESKKAVSL-KSQLEDVSILQMTLKEFQERVEDLEKERKL 373
L AAH +++ EL LK + + S+ K Q + + +M ++ + +E+L ERK
Sbjct: 70 LQAAHR---REIQEL---LKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKK 123
Query: 374 LNDNY---------------DKLLESMLDSSDSSSQPHWSNELIAEQLQQQ--------- 409
L ++Y D L S L +++S + ++ Q Q
Sbjct: 124 LIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIG 183
Query: 410 -----VSQLQDQLDAELEDKRKVLLELSRE-------KAQNEDLKLEVTNILQKHKQ-EV 456
+ +QD+ + L+ +K+ L+ + Q +D K +L KHK+ E
Sbjct: 184 KLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVES 243
Query: 457 ELLQNAATISQPPDRQSEPATHPAVL------QENTQIEPSEPKNQEEKKLSQVLNELQV 510
EL + Q A+H +L QE T + K++ ++LSQ+ E
Sbjct: 244 ELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLEEERAF 303
Query: 511 SHAET-TLELEKTRDMLILQRKINVC-------YQEELEAMMTKADND----NRDHKEKL 558
++T +L+ E+ + +L L++K+N Y+ EL+ + ++ + + N H + L
Sbjct: 304 LRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEAHSKTL 363
Query: 559 ERL 561
E L
Sbjct: 364 EEL 366
Score = 34.3 bits (77), Expect = 0.79
Identities = 50/251 (19%), Positives = 113/251 (45%), Gaps = 21/251 (8%)
Query: 232 MQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAE--------LRASIKEKVELIRLKKLL 283
+Q EE KS + ++ E+ ++ + QK E L+ +++ ++L + + L
Sbjct: 538 LQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLE--IQLSQSQTSL 595
Query: 284 HERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSL 343
+ A + +LT+ E E Q+ L AH + + E KE+ ++A+
Sbjct: 596 QQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTME----EEKEKEQRALEN 651
Query: 344 KSQLEDVSILQMTLKEFQERVE----DLEKERKLLNDNYDKLLESMLDS--SDSSSQPHW 397
Q + + LQ +E +E ++E+E + L + ++ML S S+ + Q
Sbjct: 652 HLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLASLRSELNHQHAA 711
Query: 398 SNELIAEQLQQQVSQLQDQLDAELEDKRKVLLE-LSREKAQNEDLKLEVTNILQKHKQEV 456
+ +L+ Q+++ + +L+ ++ R+ E + R E+L+ +I + K+
Sbjct: 712 AIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELRHREHHISELDKEVQ 771
Query: 457 ELLQNAATISQ 467
L +N + +++
Sbjct: 772 HLHENISALTK 782
Score = 30.8 bits (68), Expect = 8.7
Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 8/81 (9%)
Query: 1081 KESSEQGSEVSEAQTTDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPEAEVM---SDE 1137
KE +G E+ ++ + + + M +KY +S+ I++++ E + M D+
Sbjct: 782 KELEFKGKEILRIRSESNQQIRLEEMEEKYLMRESKPEDIQMIT-----ELKAMLTERDQ 836
Query: 1138 NIKQVYVEYKFYDLPLSETET 1158
IK++ + KFY L L ET
Sbjct: 837 IIKKLIEDNKFYQLELVNRET 857
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,394,507
Number of Sequences: 37866
Number of extensions: 2507187
Number of successful extensions: 12629
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 1006
Number of HSP's that attempted gapping in prelim test: 8977
Number of HSP's gapped (non-prelim): 3349
length of query: 1286
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1172
effective length of database: 13,930,794
effective search space: 16326890568
effective search space used: 16326890568
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.