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Search of human proteins with 169168628
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169168628 PREDICTED: hypothetical protein LOC100131031 [Homo
sapiens]
(252 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169168964 PREDICTED: hypothetical protein LOC100131031 [Homo ... 493 e-140
gi|169168628 PREDICTED: hypothetical protein LOC100131031 [Homo ... 493 e-140
gi|169169551 PREDICTED: hypothetical protein LOC100131031 [Homo ... 493 e-140
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 143 1e-34
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 143 1e-34
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 143 1e-34
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 135 4e-32
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 135 4e-32
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 135 4e-32
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 130 1e-30
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 119 3e-27
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 117 7e-27
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 117 7e-27
gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens] 117 1e-26
gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo... 117 1e-26
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 116 2e-26
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 116 2e-26
gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo... 115 5e-26
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 114 8e-26
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 111 7e-25
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 110 2e-24
gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens] 109 3e-24
gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Hom... 108 4e-24
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 106 2e-23
gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH po... 102 4e-22
gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH po... 102 4e-22
gi|115495445 ankyrin repeat domain 30A [Homo sapiens] 101 5e-22
gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo... 94 9e-20
gi|239755970 PREDICTED: FLJ46358 protein [Homo sapiens] 85 5e-17
gi|239750493 PREDICTED: FLJ46358 protein [Homo sapiens] 85 5e-17
>gi|169168964 PREDICTED: hypothetical protein LOC100131031 [Homo
sapiens]
Length = 252
Score = 493 bits (1269), Expect = e-140
Identities = 252/252 (100%), Positives = 252/252 (100%)
Query: 1 MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV 60
MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV
Sbjct: 1 MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV 60
Query: 61 LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE 120
LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE
Sbjct: 61 LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE 120
Query: 121 EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY 180
EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY
Sbjct: 121 EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY 180
Query: 181 GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL 240
GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL
Sbjct: 181 GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL 240
Query: 241 QRAQDVSLQERK 252
QRAQDVSLQERK
Sbjct: 241 QRAQDVSLQERK 252
>gi|169168628 PREDICTED: hypothetical protein LOC100131031 [Homo
sapiens]
Length = 252
Score = 493 bits (1269), Expect = e-140
Identities = 252/252 (100%), Positives = 252/252 (100%)
Query: 1 MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV 60
MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV
Sbjct: 1 MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV 60
Query: 61 LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE 120
LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE
Sbjct: 61 LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE 120
Query: 121 EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY 180
EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY
Sbjct: 121 EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY 180
Query: 181 GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL 240
GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL
Sbjct: 181 GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL 240
Query: 241 QRAQDVSLQERK 252
QRAQDVSLQERK
Sbjct: 241 QRAQDVSLQERK 252
>gi|169169551 PREDICTED: hypothetical protein LOC100131031 [Homo
sapiens]
Length = 252
Score = 493 bits (1269), Expect = e-140
Identities = 252/252 (100%), Positives = 252/252 (100%)
Query: 1 MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV 60
MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV
Sbjct: 1 MPLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEV 60
Query: 61 LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE 120
LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE
Sbjct: 61 LNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSE 120
Query: 121 EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY 180
EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY
Sbjct: 121 EEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQY 180
Query: 181 GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL 240
GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL
Sbjct: 181 GQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELAL 240
Query: 241 QRAQDVSLQERK 252
QRAQDVSLQERK
Sbjct: 241 QRAQDVSLQERK 252
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 143 bits (361), Expect = 1e-34
Identities = 114/355 (32%), Positives = 170/355 (47%), Gaps = 106/355 (29%)
Query: 2 PLMKAVHCQEEICVIILLECGT---------------------------------NPDLM 28
PLMKAVH QEE C I+LLECG N + +
Sbjct: 211 PLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEAL 270
Query: 29 DVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN--KDTEVL-----NKDANTPLLLA-- 79
+ N L +A+ + + E L + N ++ K T ++ N + LLL
Sbjct: 271 NKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQN 330
Query: 80 ----------------IVC---KTQQKPTMEMKDSVVKKAIERKNEQTS----------- 109
+C ++ ++ +E K+ ++K + N++T+
Sbjct: 331 IRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRK 390
Query: 110 ---KAEQEVQVTSEEEQEKLE-SENKQPQVEEARKKHERTSKG----KKDIEIVKE---- 157
KAE ++V SEE+QE+L+ SENKQPQ ++ K + G KKDI ++KE
Sbjct: 391 ERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYA 450
Query: 158 ---------------------MNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKS 196
+N + +++++LN K +TKTV++Y QQLNDLK EN L S
Sbjct: 451 IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNS 510
Query: 197 KLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQDVSLQER 251
+LEKE NKERLEAEVES H+ LA AI+E ++ V+ ++DLEL L RA DVS E+
Sbjct: 511 ELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE-RKDLELVLWRADDVSRHEK 564
Score = 30.8 bits (68), Expect = 1.2
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 24/129 (18%)
Query: 44 NTLLAEKLPSHHVNTEVLN--KDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVK--- 98
N L+AEK V++E +N KD EVL+++ + + C+ +K +++ V+
Sbjct: 858 NDLVAEK---EAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKT 914
Query: 99 ----------KAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTSKG 148
K E K+E +A QE++ E +K K Q+E+ K + + K
Sbjct: 915 HMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEK--QLEQLNKDNTASLKK 972
Query: 149 K----KDIE 153
K KD+E
Sbjct: 973 KELTLKDVE 981
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 143 bits (361), Expect = 1e-34
Identities = 114/355 (32%), Positives = 170/355 (47%), Gaps = 106/355 (29%)
Query: 2 PLMKAVHCQEEICVIILLECGT---------------------------------NPDLM 28
PLMKAVH QEE C I+LLECG N + +
Sbjct: 104 PLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEAL 163
Query: 29 DVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN--KDTEVL-----NKDANTPLLLA-- 79
+ N L +A+ + + E L + N ++ K T ++ N + LLL
Sbjct: 164 NKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQN 223
Query: 80 ----------------IVC---KTQQKPTMEMKDSVVKKAIERKNEQTS----------- 109
+C ++ ++ +E K+ ++K + N++T+
Sbjct: 224 IRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRK 283
Query: 110 ---KAEQEVQVTSEEEQEKLE-SENKQPQVEEARKKHERTSKG----KKDIEIVKE---- 157
KAE ++V SEE+QE+L+ SENKQPQ ++ K + G KKDI ++KE
Sbjct: 284 ERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYA 343
Query: 158 ---------------------MNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKS 196
+N + +++++LN K +TKTV++Y QQLNDLK EN L S
Sbjct: 344 IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNS 403
Query: 197 KLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQDVSLQER 251
+LEKE NKERLEAEVES H+ LA AI+E ++ V+ ++DLEL L RA DVS E+
Sbjct: 404 ELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE-RKDLELVLWRADDVSRHEK 457
Score = 32.7 bits (73), Expect = 0.31
Identities = 44/190 (23%), Positives = 86/190 (45%), Gaps = 40/190 (21%)
Query: 44 NTLLAEKLPSHHVNTEVLN--KDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVK--- 98
N L+AEK V++E +N KD EVL+++ + + C+ +K +++ V+
Sbjct: 751 NDLVAEK---EAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKT 807
Query: 99 ----------KAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTSKG 148
K E K+E +A QE++ E +K K Q+E+ K + + K
Sbjct: 808 HMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEK--QLEQLNKDNTASLKK 865
Query: 149 K----KDIE--------IVKEMNDDLQE-------TIKLNGKTLTKTVSQYGQQLNDLKT 189
K KD+E +E+ +L+E +K N +++K + + +++ + T
Sbjct: 866 KELTLKDVECKFSKMKTAYEEVTTELEEFKEAFAGAVKAN-NSMSKKLMKSDKKIAVIST 924
Query: 190 ENTMLKSKLE 199
+ M K ++E
Sbjct: 925 KLFMEKERME 934
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 143 bits (361), Expect = 1e-34
Identities = 114/355 (32%), Positives = 170/355 (47%), Gaps = 106/355 (29%)
Query: 2 PLMKAVHCQEEICVIILLECGT---------------------------------NPDLM 28
PLMKAVH QEE C I+LLECG N + +
Sbjct: 211 PLMKAVHSQEEACAIVLLECGANPNIEDIYGNTALHYAVYNKGTSLAERLLSHHANIEAL 270
Query: 29 DVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN--KDTEVL-----NKDANTPLLLA-- 79
+ N L +A+ + + E L + N ++ K T ++ N + LLL
Sbjct: 271 NKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQN 330
Query: 80 ----------------IVC---KTQQKPTMEMKDSVVKKAIERKNEQTS----------- 109
+C ++ ++ +E K+ ++K + N++T+
Sbjct: 331 IRISSQDMFGQTAEDYALCSDLRSIRQQILEHKNKMLKNHLRNDNQETAAMKPANLKKRK 390
Query: 110 ---KAEQEVQVTSEEEQEKLE-SENKQPQVEEARKKHERTSKG----KKDIEIVKE---- 157
KAE ++V SEE+QE+L+ SENKQPQ ++ K + G KKDI ++KE
Sbjct: 391 ERAKAEHNLKVASEEKQERLQRSENKQPQDSQSYGKKKDAMYGNFMLKKDIAMLKEELYA 450
Query: 158 ---------------------MNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKS 196
+N + +++++LN K +TKTV++Y QQLNDLK EN L S
Sbjct: 451 IKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEKMITKTVARYSQQLNDLKAENARLNS 510
Query: 197 KLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQDVSLQER 251
+LEKE NKERLEAEVES H+ LA AI+E ++ V+ ++DLEL L RA DVS E+
Sbjct: 511 ELEKEKHNKERLEAEVESLHSSLATAINEYNEIVE-RKDLELVLWRADDVSRHEK 564
Score = 30.8 bits (68), Expect = 1.2
Identities = 34/129 (26%), Positives = 59/129 (45%), Gaps = 24/129 (18%)
Query: 44 NTLLAEKLPSHHVNTEVLN--KDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVK--- 98
N L+AEK V++E +N KD EVL+++ + + C+ +K +++ V+
Sbjct: 858 NDLVAEK---EAVSSECVNLAKDNEVLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKT 914
Query: 99 ----------KAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTSKG 148
K E K+E +A QE++ E +K K Q+E+ K + + K
Sbjct: 915 HMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQKQAEYEK--QLEQLNKDNTASLKK 972
Query: 149 K----KDIE 153
K KD+E
Sbjct: 973 KELTLKDVE 981
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 135 bits (339), Expect = 4e-32
Identities = 113/363 (31%), Positives = 166/363 (45%), Gaps = 115/363 (31%)
Query: 2 PLMKAVHCQEEICVII---------------------------------LLECGTNPDLM 28
PLMKAVHCQEE C II LL N + +
Sbjct: 203 PLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEAL 262
Query: 29 DVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN--KDTEVL-----NKDANTPLLL--- 78
+ N L +A+ + + E L + N ++ K T ++ N + LLL
Sbjct: 263 NKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQN 322
Query: 79 ----------------AIVC--KTQQKPTMEMKDSVVKKAIERKNEQTS----------- 109
A C ++ Q+ +E K+ ++K + N++T+
Sbjct: 323 IHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRK 382
Query: 110 ------------KAEQEVQVTSEEEQEKLE-SENKQPQVEEA--RKKHE----------- 143
KAE ++V SEE+QE+LE SENKQPQ ++ +KK E
Sbjct: 383 KRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDI 442
Query: 144 ----------------RTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDL 187
+ K ++I+ + E+N + +++++LN + +TK V+QY QQLNDL
Sbjct: 443 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDL 502
Query: 188 KTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQDVS 247
K EN L SKLEKE NKERLEAEVES H+ LA AI+E ++ + ++DLEL L RA DVS
Sbjct: 503 KAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNE-ILERKDLELVLWRADDVS 561
Query: 248 LQE 250
E
Sbjct: 562 RHE 564
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 135 bits (339), Expect = 4e-32
Identities = 113/363 (31%), Positives = 166/363 (45%), Gaps = 115/363 (31%)
Query: 2 PLMKAVHCQEEICVII---------------------------------LLECGTNPDLM 28
PLMKAVHCQEE C II LL N + +
Sbjct: 232 PLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEAL 291
Query: 29 DVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN--KDTEVL-----NKDANTPLLL--- 78
+ N L +A+ + + E L + N ++ K T ++ N + LLL
Sbjct: 292 NKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQN 351
Query: 79 ----------------AIVC--KTQQKPTMEMKDSVVKKAIERKNEQTS----------- 109
A C ++ Q+ +E K+ ++K + N++T+
Sbjct: 352 IHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRK 411
Query: 110 ------------KAEQEVQVTSEEEQEKLE-SENKQPQVEEA--RKKHE----------- 143
KAE ++V SEE+QE+LE SENKQPQ ++ +KK E
Sbjct: 412 KRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDI 471
Query: 144 ----------------RTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDL 187
+ K ++I+ + E+N + +++++LN + +TK V+QY QQLNDL
Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDL 531
Query: 188 KTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQDVS 247
K EN L SKLEKE NKERLEAEVES H+ LA AI+E ++ + ++DLEL L RA DVS
Sbjct: 532 KAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNE-ILERKDLELVLWRADDVS 590
Query: 248 LQE 250
E
Sbjct: 591 RHE 593
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 135 bits (339), Expect = 4e-32
Identities = 113/363 (31%), Positives = 166/363 (45%), Gaps = 115/363 (31%)
Query: 2 PLMKAVHCQEEICVII---------------------------------LLECGTNPDLM 28
PLMKAVHCQEE C II LL N + +
Sbjct: 232 PLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEAL 291
Query: 29 DVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN--KDTEVL-----NKDANTPLLL--- 78
+ N L +A+ + + E L + N ++ K T ++ N + LLL
Sbjct: 292 NKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQN 351
Query: 79 ----------------AIVC--KTQQKPTMEMKDSVVKKAIERKNEQTS----------- 109
A C ++ Q+ +E K+ ++K + N++T+
Sbjct: 352 IHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRK 411
Query: 110 ------------KAEQEVQVTSEEEQEKLE-SENKQPQVEEA--RKKHE----------- 143
KAE ++V SEE+QE+LE SENKQPQ ++ +KK E
Sbjct: 412 KRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDI 471
Query: 144 ----------------RTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDL 187
+ K ++I+ + E+N + +++++LN + +TK V+QY QQLNDL
Sbjct: 472 AMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDL 531
Query: 188 KTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQDVS 247
K EN L SKLEKE NKERLEAEVES H+ LA AI+E ++ + ++DLEL L RA DVS
Sbjct: 532 KAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNE-ILERKDLELVLWRADDVS 590
Query: 248 LQE 250
E
Sbjct: 591 RHE 593
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 130 bits (326), Expect = 1e-30
Identities = 75/156 (48%), Positives = 105/156 (67%), Gaps = 4/156 (2%)
Query: 93 KDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTSKGKK-- 150
K ++ A ++ N + S + +E + S + L+ E ++E K++ K KK
Sbjct: 885 KQKEIEMAQKKMNSENSHSHEEEKDLSHKNS-MLQEEIAMLRLEIDTIKNQNQEKEKKCF 943
Query: 151 -DIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLE 209
D++IVKE N+DLQ+TIK N +TLT+T+SQY +L+ L EN ML SKLE E Q+KERLE
Sbjct: 944 EDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLE 1003
Query: 210 AEVESFHARLAAAISECDQSVKTKRDLELALQRAQD 245
AEVES+H+RLAAAI + DQS +KR+LELA QRA+D
Sbjct: 1004 AEVESYHSRLAAAIHDRDQSETSKRELELAFQRARD 1039
Score = 92.0 bits (227), Expect = 4e-19
Identities = 73/222 (32%), Positives = 110/222 (49%), Gaps = 30/222 (13%)
Query: 3 LMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN 62
LMKAV CQEE C ILLE G +P+L DV+ N ALHYAVYNE+ +A KL + N E N
Sbjct: 117 LMKAVQCQEEKCATILLEHGADPNLADVHGNTALHYAVYNEDISVATKLLLYDANIEAKN 176
Query: 63 KDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEE 122
KD TPLLLA+ K QQ M + ++KK + K E Q+ SE +
Sbjct: 177 KDD-------LTPLLLAVSGKKQQ-----MVEFLIKK--KANVNAVDKLESSHQLISEYK 222
Query: 123 QEKLESENKQ--PQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTK----- 175
+E++ + Q V+E+ + GK ++ +DD E + + K + K
Sbjct: 223 EERIPKHSSQNSNSVDESSEDSLSRLSGKPGVDDSWPTSDD--EDLNFDTKNVPKPSLAK 280
Query: 176 --TVSQYGQQ-----LNDLKTENTMLKSKLEKENQNKERLEA 210
T SQ ++ ++T N L + ++Q++ +E+
Sbjct: 281 LMTASQQSRKNLEATYGTVRTGNRTLFEDRDSDSQDEVVVES 322
Score = 70.9 bits (172), Expect = 1e-12
Identities = 42/79 (53%), Positives = 53/79 (67%), Gaps = 2/79 (2%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKA-EQEVQVTSEEEQEKLESENKQPQVEEARKKHERT 145
KPT+EMKDSV KA K+ QTSKA E +++V SEEEQE+ SEN QPQVEE RKKH R
Sbjct: 497 KPTIEMKDSVPNKAGGMKDVQTSKAAEHDLEVASEEEQEREGSENNQPQVEEERKKH-RN 555
Query: 146 SKGKKDIEIVKEMNDDLQE 164
++ + I DD ++
Sbjct: 556 NEMEVSANIHDGATDDAED 574
Score = 38.9 bits (89), Expect = 0.004
Identities = 37/153 (24%), Positives = 70/153 (45%), Gaps = 13/153 (8%)
Query: 97 VKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHE----------RTS 146
+KK +E K +QE++ E E+E +N + ++E +TS
Sbjct: 1332 LKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHGDLKTS 1391
Query: 147 KGKKDIEI--VKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQN 204
+ + DI+I +K DDL ++ G ++ +L + T+ K K EK +N
Sbjct: 1392 QFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQK-KCEKLQKN 1450
Query: 205 KERLEAEVESFHARLAAAISECDQSVKTKRDLE 237
K++LE EV + + + + E Q + K+++E
Sbjct: 1451 KKKLEQEVINLRSHIERNMVELGQVKQYKQEIE 1483
Score = 32.7 bits (73), Expect = 0.31
Identities = 32/147 (21%), Positives = 65/147 (44%), Gaps = 8/147 (5%)
Query: 66 EVLNKDANTPLLLAIVCKTQQK-PTMEMKDSVVKKAIERKN---EQTSKAEQEVQVTSEE 121
+V N N +L + KT+ K ++E++ + A+ K E+ K + Q +E
Sbjct: 1051 DVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKE 1110
Query: 122 EQEKLESENKQPQ--VEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQ 179
++K ++E + + + ER S+ + + ++++ DD KT+ Q
Sbjct: 1111 MEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHNKADNKEKTVINIQDQ 1170
Query: 180 YGQQLNDLKTENTMLKSKLEKENQNKE 206
+ + L+ E+ K L E +NKE
Sbjct: 1171 FHAIVQKLQAESE--KQSLLLEERNKE 1195
Score = 32.3 bits (72), Expect = 0.40
Identities = 24/110 (21%), Positives = 55/110 (50%), Gaps = 7/110 (6%)
Query: 81 VCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARK 140
V + + T E+K + + +E + E S + EEE+ + + E+ R+
Sbjct: 762 VLQRELSETKEIKSQLEHQKVEWERELCSL---RFSLNQEEEKRRNADTLYEKIREQLRR 818
Query: 141 KHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTE 190
K E+ +K++E+ +++ LQ T+++ +T+ ++Q Q+ ND + +
Sbjct: 819 KEEQY---RKEVEVKQQLELSLQ-TLEMELRTVKSNLNQVVQERNDAQRQ 864
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 119 bits (298), Expect = 3e-27
Identities = 73/186 (39%), Positives = 110/186 (59%), Gaps = 21/186 (11%)
Query: 85 QQKPTMEMKDSVVKKAIERKN-----------EQTSKAEQEVQVTSEEEQEKLESEN--- 130
+ + +E K+ KK +E K +T++ + EE + L EN
Sbjct: 458 KNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCIL 517
Query: 131 -------KQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQ 183
+Q E+ +K KDI+IVKE N L++ IKLN + +T+T +Y Q+
Sbjct: 518 KADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQE 577
Query: 184 LNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRA 243
LNDLK ENT L ++L KE ++K+RLEA++ES+ +RLAAAIS+ +SVKT+R+L+LAL+R
Sbjct: 578 LNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERT 637
Query: 244 QDVSLQ 249
QDVS+Q
Sbjct: 638 QDVSVQ 643
Score = 107 bits (266), Expect = 1e-23
Identities = 53/102 (51%), Positives = 68/102 (66%), Gaps = 7/102 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL++AVHCQEE C +ILLE G NP+L D+Y N ALHYAVY+E+T LAEKL SH + E L
Sbjct: 103 PLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEAL 162
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIER 103
+KD NTPLL AI+CK ++ +K A++R
Sbjct: 163 DKDN-------NTPLLFAIICKKEKMVEFLLKKKASSHAVDR 197
Score = 66.2 bits (160), Expect = 3e-11
Identities = 65/209 (31%), Positives = 95/209 (45%), Gaps = 38/209 (18%)
Query: 47 LAEKLP--SHHVNTEVLNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERK 104
++E LP SH ++N E A P L KP+ E++D VK A++RK
Sbjct: 305 VSEPLPGSSHEKGNRIVNGQGE--GPPAKHPSL---------KPSTEVEDPAVKGAVQRK 353
Query: 105 NEQTSKAEQEVQVTSEEEQEKLE-SENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQ 163
N QT +AEQ + V SEEEQ++ E SE KQPQV+E T+K +K I++ + + D
Sbjct: 354 NVQTLRAEQALPVASEEEQQRHERSEKKQPQVKEG----NNTNKSEK-IQLSENICDSTS 408
Query: 164 ETIKLNGKTLTKTVSQYGQQL----------------NDLKTENTMLKSKLEKENQNKER 207
K Y QQ N+ KT ML K +E + KE+
Sbjct: 409 SAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEK 468
Query: 208 -LEAEVESFHARLAAAISECDQSVKTKRD 235
+ EVE+ +L + + KT R+
Sbjct: 469 QYKKEVEA--KQLEPTVQSLEMKSKTARN 495
Score = 33.1 bits (74), Expect = 0.24
Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL+ A+ C++E V LL+ + +D +AL AVY ++ + L N +V
Sbjct: 169 PLLFAIICKKEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ--NIDVF 226
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
+D + +DA + + K QQ+ +E K ++KK K++ S E V + E
Sbjct: 227 AQD--MCGRDAEDYAISHHLTKIQQQ-ILEHKKKILKK---EKSDVGSSDESAVSIFHEL 280
Query: 122 EQEKL-ESENKQPQVEEARKKHERTSK 147
+ L S++K V + E+ S+
Sbjct: 281 RVDSLPASDDKDLNVATKQCVPEKVSE 307
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 117 bits (294), Expect = 7e-27
Identities = 72/186 (38%), Positives = 110/186 (59%), Gaps = 21/186 (11%)
Query: 85 QQKPTMEMKDSVVKKAIERKN-----------EQTSKAEQEVQVTSEEEQEKLESEN--- 130
+ + +E K+ KK +E K +T++ + EE + L EN
Sbjct: 458 KNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCIL 517
Query: 131 -------KQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQ 183
+Q E+ +K KDI+IVKE N L++ IKLN + +T+T +Y Q+
Sbjct: 518 KADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQE 577
Query: 184 LNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRA 243
LNDLK ENT L ++L KE ++K+RLEA++ES+ +RLAAAIS+ +SVKT+R+L+LAL+R
Sbjct: 578 LNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERT 637
Query: 244 QDVSLQ 249
+DVS+Q
Sbjct: 638 RDVSVQ 643
Score = 106 bits (265), Expect = 2e-23
Identities = 53/102 (51%), Positives = 68/102 (66%), Gaps = 7/102 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL++AVHCQEE C +ILLE G NP+L D+Y N ALHYAVY+E+T LAEKL SH + E L
Sbjct: 103 PLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEAL 162
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIER 103
+KD NTPLL AI+CK ++ +K A++R
Sbjct: 163 DKDN-------NTPLLFAIICKKEKMVEFLLKRKASSHAVDR 197
Score = 67.4 bits (163), Expect = 1e-11
Identities = 66/209 (31%), Positives = 95/209 (45%), Gaps = 38/209 (18%)
Query: 47 LAEKLP--SHHVNTEVLNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERK 104
++E LP SH ++N E A P L KP+ E++D VK A++RK
Sbjct: 305 VSEPLPGSSHEKGNRIVNGQGE--GPPAKHPSL---------KPSTEVEDPAVKGAVQRK 353
Query: 105 NEQTSKAEQEVQVTSEEEQEKLE-SENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQ 163
N QT +AEQ + V SEEEQE+ E SE KQPQV+E T+K +K I++ + + D
Sbjct: 354 NVQTLRAEQALPVASEEEQERHERSEKKQPQVKEG----NNTNKSEK-IQLSENICDSTS 408
Query: 164 ETIKLNGKTLTKTVSQYGQQL----------------NDLKTENTMLKSKLEKENQNKER 207
K Y QQ N+ KT ML K +E + KE+
Sbjct: 409 SAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEK 468
Query: 208 -LEAEVESFHARLAAAISECDQSVKTKRD 235
+ EVE+ +L + + KT R+
Sbjct: 469 QYKKEVEA--KQLEPTVQSLEMKSKTARN 495
Score = 33.1 bits (74), Expect = 0.24
Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL+ A+ C++E V LL+ + +D +AL AVY ++ + L N +V
Sbjct: 169 PLLFAIICKKEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ--NIDVF 226
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
+D + +DA + + K QQ+ +E K ++KK K++ S E V + E
Sbjct: 227 AQD--MCGRDAEDYAISHHLTKIQQQ-ILEHKKKILKK---EKSDVGSSDESAVSIFHEL 280
Query: 122 EQEKL-ESENKQPQVEEARKKHERTSK 147
+ L S++K V + E+ S+
Sbjct: 281 RVDSLPASDDKDLNVATKQCVPEKVSE 307
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 117 bits (294), Expect = 7e-27
Identities = 72/186 (38%), Positives = 110/186 (59%), Gaps = 21/186 (11%)
Query: 85 QQKPTMEMKDSVVKKAIERKN-----------EQTSKAEQEVQVTSEEEQEKLESEN--- 130
+ + +E K+ KK +E K +T++ + EE + L EN
Sbjct: 458 KNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCIL 517
Query: 131 -------KQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQ 183
+Q E+ +K KDI+IVKE N L++ IKLN + +T+T +Y Q+
Sbjct: 518 KADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQE 577
Query: 184 LNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRA 243
LNDLK ENT L ++L KE ++K+RLEA++ES+ +RLAAAIS+ +SVKT+R+L+LAL+R
Sbjct: 578 LNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERT 637
Query: 244 QDVSLQ 249
+DVS+Q
Sbjct: 638 RDVSVQ 643
Score = 107 bits (266), Expect = 1e-23
Identities = 53/102 (51%), Positives = 68/102 (66%), Gaps = 7/102 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL++AVHCQEE C +ILLE G NP+L D+Y N ALHYAVY+E+T LAEKL SH + E L
Sbjct: 103 PLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEAL 162
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIER 103
+KD NTPLL AI+CK ++ +K A++R
Sbjct: 163 DKDN-------NTPLLFAIICKKEKMVEFLLKKKASSHAVDR 197
Score = 67.4 bits (163), Expect = 1e-11
Identities = 66/209 (31%), Positives = 95/209 (45%), Gaps = 38/209 (18%)
Query: 47 LAEKLP--SHHVNTEVLNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERK 104
++E LP SH ++N E A P L KP+ E++D VK A++RK
Sbjct: 305 VSEPLPGSSHEKGNRIVNGQGE--GPPAKHPSL---------KPSTEVEDPAVKGAVQRK 353
Query: 105 NEQTSKAEQEVQVTSEEEQEKLE-SENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQ 163
N QT +AEQ + V SEEEQE+ E SE KQPQV+E T+K +K I++ + + D
Sbjct: 354 NVQTLRAEQALPVASEEEQERHERSEKKQPQVKEG----NNTNKSEK-IQLSENICDSTS 408
Query: 164 ETIKLNGKTLTKTVSQYGQQL----------------NDLKTENTMLKSKLEKENQNKER 207
K Y QQ N+ KT ML K +E + KE+
Sbjct: 409 SAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEK 468
Query: 208 -LEAEVESFHARLAAAISECDQSVKTKRD 235
+ EVE+ +L + + KT R+
Sbjct: 469 QYKKEVEA--KQLEPTVQSLEMKSKTARN 495
Score = 33.1 bits (74), Expect = 0.24
Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL+ A+ C++E V LL+ + +D +AL AVY ++ + L N +V
Sbjct: 169 PLLFAIICKKEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ--NIDVF 226
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
+D + +DA + + K QQ+ +E K ++KK K++ S E V + E
Sbjct: 227 AQD--MCGRDAEDYAISHHLTKIQQQ-ILEHKKKILKK---EKSDVGSSDESAVSIFHEL 280
Query: 122 EQEKL-ESENKQPQVEEARKKHERTSK 147
+ L S++K V + E+ S+
Sbjct: 281 RVDSLPASDDKDLNVATKQCVPEKVSE 307
>gi|239756999 PREDICTED: ankyrin repeat domain 62 [Homo sapiens]
Length = 917
Score = 117 bits (292), Expect = 1e-26
Identities = 64/160 (40%), Positives = 101/160 (63%), Gaps = 1/160 (0%)
Query: 83 KTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKH 142
K Q K T++ + +K N+ E+E + E + E + +++ + ++
Sbjct: 523 KKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQN 582
Query: 143 ERT-SKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKE 201
+ T +K KDIEI+KE N+DL++T+K N +TLTKT+++Y ++LN L ENTML S+L+KE
Sbjct: 583 QETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKE 642
Query: 202 NQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQ 241
Q+ RLE E+ES+ RLAAA+ + DQ +KRDL+LA Q
Sbjct: 643 KQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQ 682
Score = 84.0 bits (206), Expect = 1e-16
Identities = 86/324 (26%), Positives = 132/324 (40%), Gaps = 104/324 (32%)
Query: 3 LMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN 62
L+KAV CQEE+C ILLE G NP++ D+Y N ALHYA+ NEN +A KL ++
Sbjct: 109 LIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAY-------G 161
Query: 63 KDTEVLNKDANTPLLLAIVCKTQQ--------KPTMEMKDSVVKKA--IERKNEQTSKAE 112
D E ++D +T LLLA+ K +Q KP + D+ + A + +N TS
Sbjct: 162 ADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVY 221
Query: 113 QEVQ-----------------------------------------------------VTS 119
Q +Q +TS
Sbjct: 222 QLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTS 281
Query: 120 EEEQEKLES-ENKQPQVEEARKKHERTSKGKKDIEIVKEM--------NDDLQETIKL-- 168
E EQE+LE E+ QPQVEE KK K +E+ + + NDD+ E I
Sbjct: 282 EGEQERLEGCESSQPQVEEKMKKCR-----NKKMEVSRNVHADDSDNYNDDVDELIHKIK 336
Query: 169 -----NGKTLTKTVSQYGQQLNDLKTENTMLKSKL-------------EKENQNKERLEA 210
N ++ K ++ + E + +KS++ EK +++ E +
Sbjct: 337 NRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYS 396
Query: 211 EVESFHARLAAAISECDQSVKTKR 234
+ E+F + + EC V +
Sbjct: 397 DDENFMLLIKQSGMECKDFVSLSK 420
Score = 30.8 bits (68), Expect = 1.2
Identities = 26/123 (21%), Positives = 56/123 (45%), Gaps = 12/123 (9%)
Query: 103 RKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDL 162
+K + K +QV E+ EKL++E + ++EE K + K+ + E +
Sbjct: 795 KKADNQEKTIINIQVKCEDTVEKLQAECR--KLEENNKGLMKECTLLKERQCQYEKEKEE 852
Query: 163 QETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAA 222
+E ++ Q ++++D + +L++ LE ++ + LE E +S +L
Sbjct: 853 REVVR----------RQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLGQM 902
Query: 223 ISE 225
S+
Sbjct: 903 RSQ 905
>gi|239751514 PREDICTED: ankyrin repeat domain 62 isoform 4 [Homo
sapiens]
Length = 917
Score = 117 bits (292), Expect = 1e-26
Identities = 64/160 (40%), Positives = 101/160 (63%), Gaps = 1/160 (0%)
Query: 83 KTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKH 142
K Q K T++ + +K N+ E+E + E + E + +++ + ++
Sbjct: 523 KKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQN 582
Query: 143 ERT-SKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKE 201
+ T +K KDIEI+KE N+DL++T+K N +TLTKT+++Y ++LN L ENTML S+L+KE
Sbjct: 583 QETENKYFKDIEIIKENNEDLEKTLKRNEETLTKTITRYSKELNVLMDENTMLNSELQKE 642
Query: 202 NQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQ 241
Q+ RLE E+ES+ RLAAA+ + DQ +KRDL+LA Q
Sbjct: 643 KQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQ 682
Score = 84.0 bits (206), Expect = 1e-16
Identities = 86/324 (26%), Positives = 132/324 (40%), Gaps = 104/324 (32%)
Query: 3 LMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN 62
L+KAV CQEE+C ILLE G NP++ D+Y N ALHYA+ NEN +A KL ++
Sbjct: 109 LIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAY-------G 161
Query: 63 KDTEVLNKDANTPLLLAIVCKTQQ--------KPTMEMKDSVVKKA--IERKNEQTSKAE 112
D E ++D +T LLLA+ K +Q KP + D+ + A + +N TS
Sbjct: 162 ADIEARSQDGHTSLLLAVNRKKEQMVSFLLKKKPDLTAIDNFGRTALILAARNGSTSVVY 221
Query: 113 QEVQ-----------------------------------------------------VTS 119
Q +Q +TS
Sbjct: 222 QLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRRKSLQNSNSEQDLEMTS 281
Query: 120 EEEQEKLES-ENKQPQVEEARKKHERTSKGKKDIEIVKEM--------NDDLQETIKL-- 168
E EQE+LE E+ QPQVEE KK K +E+ + + NDD+ E I
Sbjct: 282 EGEQERLEGCESSQPQVEEKMKKCR-----NKKMEVSRNVHADDSDNYNDDVDELIHKIK 336
Query: 169 -----NGKTLTKTVSQYGQQLNDLKTENTMLKSKL-------------EKENQNKERLEA 210
N ++ K ++ + E + +KS++ EK +++ E +
Sbjct: 337 NRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYS 396
Query: 211 EVESFHARLAAAISECDQSVKTKR 234
+ E+F + + EC V +
Sbjct: 397 DDENFMLLIKQSGMECKDFVSLSK 420
Score = 30.8 bits (68), Expect = 1.2
Identities = 26/123 (21%), Positives = 56/123 (45%), Gaps = 12/123 (9%)
Query: 103 RKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDL 162
+K + K +QV E+ EKL++E + ++EE K + K+ + E +
Sbjct: 795 KKADNQEKTIINIQVKCEDTVEKLQAECR--KLEENNKGLMKECTLLKERQCQYEKEKEE 852
Query: 163 QETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAA 222
+E ++ Q ++++D + +L++ LE ++ + LE E +S +L
Sbjct: 853 REVVR----------RQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLGQM 902
Query: 223 ISE 225
S+
Sbjct: 903 RSQ 905
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 116 bits (291), Expect = 2e-26
Identities = 73/197 (37%), Positives = 113/197 (57%), Gaps = 10/197 (5%)
Query: 54 HHVNTEVLNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQ 113
H N E L + + K+ Q +PT++ + K A N+ E+
Sbjct: 456 HKKNREELERKEKQYKKEVEAK---------QLEPTVQSLEMKPKTARNTPNQDFHNHEE 506
Query: 114 EVQVTSEEEQEKLESENKQPQVEEARKKH-ERTSKGKKDIEIVKEMNDDLQETIKLNGKT 172
+ E K + + ++ + + E+ +K KDI+I KE N L++ IKLN +
Sbjct: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEM 566
Query: 173 LTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKT 232
+TKT Y Q+LNDLK ENT L S+L KE ++K++LEAE+ES+ +RLAAAIS+ ++VKT
Sbjct: 567 ITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKT 626
Query: 233 KRDLELALQRAQDVSLQ 249
+R+L+LAL+R QD+S Q
Sbjct: 627 ERNLKLALERTQDISEQ 643
Score = 106 bits (265), Expect = 2e-23
Identities = 52/102 (50%), Positives = 70/102 (68%), Gaps = 7/102 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL++AVHCQEE C +ILLE G NP+L D+Y N ALHYAVY+E+T LAEKL H
Sbjct: 103 PLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFH------- 155
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIER 103
++ E L+KD+NTPLL AI+CK ++ +K+ A++R
Sbjct: 156 GENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDR 197
Score = 63.2 bits (152), Expect = 2e-10
Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 28/208 (13%)
Query: 52 PSHHVNTEVLNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKA 111
PSH ++N E A P L KP+ EM+D VK A++ KN QT +A
Sbjct: 312 PSHGKGNRIVNGKGE--GPPAKHPSL---------KPSTEMEDPAVKGAVQXKNVQTLRA 360
Query: 112 EQEVQVTSEEEQEKLE-SENKQPQVEEARK--KHERTSKGKKDIEIVKEMNDDLQETIKL 168
EQ + V SEEEQ++ E SE KQPQV E K E+ + D +
Sbjct: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
Query: 169 NGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKEN------QNKERLEAEVESFHARLAAA 222
GKT + Q+ ++L + T+ + EK N +N+E LE + + + +
Sbjct: 421 IGKTYPQ---QFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEV--- 474
Query: 223 ISECDQSVKTKRDLELALQRAQDVSLQE 250
E Q T + LE+ + A++ Q+
Sbjct: 475 --EAKQLEPTVQSLEMKPKTARNTPNQD 500
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 116 bits (291), Expect = 2e-26
Identities = 73/197 (37%), Positives = 113/197 (57%), Gaps = 10/197 (5%)
Query: 54 HHVNTEVLNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQ 113
H N E L + + K+ Q +PT++ + K A N+ E+
Sbjct: 456 HKKNREELERKEKQYKKEVEAK---------QLEPTVQSLEMKPKTARNTPNQDFHNHEE 506
Query: 114 EVQVTSEEEQEKLESENKQPQVEEARKKH-ERTSKGKKDIEIVKEMNDDLQETIKLNGKT 172
+ E K + + ++ + + E+ +K KDI+I KE N L++ IKLN +
Sbjct: 507 VKDLMDENCILKTDIAILRQEICTMKNDNLEKENKYLKDIKIAKETNAALEKCIKLNEEM 566
Query: 173 LTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKT 232
+TKT Y Q+LNDLK ENT L S+L KE ++K++LEAE+ES+ +RLAAAIS+ ++VKT
Sbjct: 567 ITKTAFWYQQELNDLKAENTRLNSELLKEKESKKKLEAEIESYQSRLAAAISKHSENVKT 626
Query: 233 KRDLELALQRAQDVSLQ 249
+R+L+LAL+R QD+S Q
Sbjct: 627 ERNLKLALERTQDISEQ 643
Score = 106 bits (265), Expect = 2e-23
Identities = 52/102 (50%), Positives = 70/102 (68%), Gaps = 7/102 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL++AVHCQEE C +ILLE G NP+L D+Y N ALHYAVY+E+T LAEKL H
Sbjct: 103 PLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFH------- 155
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIER 103
++ E L+KD+NTPLL AI+CK ++ +K+ A++R
Sbjct: 156 GENIEALDKDSNTPLLFAIICKKEKMVEFLLKNKASTHAVDR 197
Score = 63.2 bits (152), Expect = 2e-10
Identities = 61/208 (29%), Positives = 93/208 (44%), Gaps = 28/208 (13%)
Query: 52 PSHHVNTEVLNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKA 111
PSH ++N E A P L KP+ EM+D VK A++ KN QT +A
Sbjct: 312 PSHGKGNRIVNGKGE--GPPAKHPSL---------KPSTEMEDPAVKGAVQXKNVQTLRA 360
Query: 112 EQEVQVTSEEEQEKLE-SENKQPQVEEARK--KHERTSKGKKDIEIVKEMNDDLQETIKL 168
EQ + V SEEEQ++ E SE KQPQV E K E+ + D +
Sbjct: 361 EQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSEKIQLSENICHSTFSAAADRLTQQRK 420
Query: 169 NGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKEN------QNKERLEAEVESFHARLAAA 222
GKT + Q+ ++L + T+ + EK N +N+E LE + + + +
Sbjct: 421 IGKTYPQ---QFPKKLKEEHDRCTLKQENEEKTNVNMLHKKNREELERKEKQYKKEV--- 474
Query: 223 ISECDQSVKTKRDLELALQRAQDVSLQE 250
E Q T + LE+ + A++ Q+
Sbjct: 475 --EAKQLEPTVQSLEMKPKTARNTPNQD 500
>gi|239746016 PREDICTED: ankyrin repeat domain 62 isoform 1 [Homo
sapiens]
Length = 917
Score = 115 bits (287), Expect = 5e-26
Identities = 63/160 (39%), Positives = 100/160 (62%), Gaps = 1/160 (0%)
Query: 83 KTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKH 142
K Q K T++ + +K N+ E+E + E + E + +++ + ++
Sbjct: 523 KKQSKLTLKSLEVELKTVRSNSNQNFHTHERERDLWQENHLMRDEIARLRLEIDTIKHQN 582
Query: 143 ERT-SKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKE 201
+ T +K KDIEI+KE N+DL++T+K N + LTKT+++Y ++LN L ENTML S+L+KE
Sbjct: 583 QETENKYFKDIEIIKENNEDLEKTLKRNEEALTKTITRYSKELNVLMDENTMLNSELQKE 642
Query: 202 NQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQ 241
Q+ RLE E+ES+ RLAAA+ + DQ +KRDL+LA Q
Sbjct: 643 KQSMSRLETEMESYRCRLAAALCDHDQRQSSKRDLQLAFQ 682
Score = 84.0 bits (206), Expect = 1e-16
Identities = 86/324 (26%), Positives = 132/324 (40%), Gaps = 104/324 (32%)
Query: 3 LMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN 62
L+KAV CQEE+C ILLE G NP++ D+Y N ALHYA+ NEN +A KL ++
Sbjct: 109 LIKAVQCQEEVCASILLEHGANPNVRDMYGNTALHYAIDNENISMARKLLAY-------G 161
Query: 63 KDTEVLNKDANTPLLLAIVCKTQQ--------KPTMEMKDSVVKKA--IERKNEQTSKAE 112
D E ++D +T LLLA+ K +Q KP + D+ + A + +N TS
Sbjct: 162 ADIEARSQDGHTSLLLAVNRKKEQMVAFLLKKKPDLTAIDNFGRTALILAARNGSTSVVY 221
Query: 113 QEVQ-----------------------------------------------------VTS 119
Q +Q +TS
Sbjct: 222 QLLQHNIDVFCQDISGWTAEDYAVASKFQAIRGMISEYKANKRCKSLQNSNSEQDLEMTS 281
Query: 120 EEEQEKLES-ENKQPQVEEARKKHERTSKGKKDIEIVKEM--------NDDLQETIKL-- 168
E EQE+LE E+ QPQVEE KK K +E+ + + NDD+ E I
Sbjct: 282 EGEQERLEGCESSQPQVEEKMKKCR-----NKKMEVSRNVHADDSDNYNDDVDELIHKIK 336
Query: 169 -----NGKTLTKTVSQYGQQLNDLKTENTMLKSKL-------------EKENQNKERLEA 210
N ++ K ++ + E + +KS++ EK +++ E +
Sbjct: 337 NRKPDNHQSPGKENGEFDRLARKTSNEKSKVKSQIYFTDDLNDISGSSEKTSEDDELPYS 396
Query: 211 EVESFHARLAAAISECDQSVKTKR 234
+ E+F + + EC V +
Sbjct: 397 DDENFMLLIEQSGMECKDFVSLSK 420
Score = 30.8 bits (68), Expect = 1.2
Identities = 26/123 (21%), Positives = 56/123 (45%), Gaps = 12/123 (9%)
Query: 103 RKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDL 162
+K + K +QV E+ EKL++E + ++EE K + K+ + E +
Sbjct: 795 KKADNQEKTIINIQVKCEDTVEKLQAECR--KLEENNKGLMKECTLLKERQCQYEKEKEE 852
Query: 163 QETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAA 222
+E ++ Q ++++D + +L++ LE ++ + LE E +S +L
Sbjct: 853 REVVR----------RQLQREVDDALNKQLLLEAMLEISSERRINLEDEAQSLKKKLGQM 902
Query: 223 ISE 225
S+
Sbjct: 903 RSQ 905
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 114 bits (285), Expect = 8e-26
Identities = 71/186 (38%), Positives = 109/186 (58%), Gaps = 21/186 (11%)
Query: 85 QQKPTMEMKDSVVKKAIERKN-----------EQTSKAEQEVQVTSEEEQEKLESEN--- 130
+ + +E K+ KK +E K +T++ + EE + L EN
Sbjct: 458 KNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNRDFHNHEEMKGLMDENCIL 517
Query: 131 -------KQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQ 183
+Q E+ +K KDI+IVKE N L++ IKLN + +T+T +Y Q+
Sbjct: 518 KADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQE 577
Query: 184 LNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRA 243
LN LK ENT L ++L KE ++K+RLEA++ES+ +RLAAAIS+ +SVKT+R+L+LAL+R
Sbjct: 578 LNYLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERT 637
Query: 244 QDVSLQ 249
+DVS+Q
Sbjct: 638 RDVSVQ 643
Score = 106 bits (265), Expect = 2e-23
Identities = 53/102 (51%), Positives = 68/102 (66%), Gaps = 7/102 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL++AVHCQEE C +ILLE G NP+L D+Y N ALHYAVY+E+T LAEKL SH + E L
Sbjct: 103 PLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEAL 162
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIER 103
+KD NTPLL AI+CK ++ +K A++R
Sbjct: 163 DKDN-------NTPLLFAIICKKEKMVEFLLKRKASSHAVDR 197
Score = 67.4 bits (163), Expect = 1e-11
Identities = 66/209 (31%), Positives = 95/209 (45%), Gaps = 38/209 (18%)
Query: 47 LAEKLP--SHHVNTEVLNKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERK 104
++E LP SH ++N E A P L KP+ E++D VK A++RK
Sbjct: 305 VSEPLPGSSHEKGNRIVNGQGE--GPPAKHPSL---------KPSTEVEDPAVKGAVQRK 353
Query: 105 NEQTSKAEQEVQVTSEEEQEKLE-SENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQ 163
N QT +AEQ + V SEEEQE+ E SE KQPQV+E T+K +K I++ + + D
Sbjct: 354 NVQTLRAEQALPVASEEEQERHERSEKKQPQVKEG----NNTNKSEK-IQLSENICDSTS 408
Query: 164 ETIKLNGKTLTKTVSQYGQQL----------------NDLKTENTMLKSKLEKENQNKER 207
K Y QQ N+ KT ML K +E + KE+
Sbjct: 409 SAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEK 468
Query: 208 -LEAEVESFHARLAAAISECDQSVKTKRD 235
+ EVE+ +L + + KT R+
Sbjct: 469 QYKKEVEA--KQLEPTVQSLEMKSKTARN 495
Score = 33.1 bits (74), Expect = 0.24
Identities = 38/147 (25%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL+ A+ C++E V LL+ + +D +AL AVY ++ + L N +V
Sbjct: 169 PLLFAIICKKEKMVEFLLKRKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQ--NIDVF 226
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
+D + +DA + + K QQ+ +E K ++KK K++ S E V + E
Sbjct: 227 AQD--MCGRDAEDYAISHHLTKIQQQ-ILEHKKKILKK---EKSDVGSSDESAVSIFHEL 280
Query: 122 EQEKL-ESENKQPQVEEARKKHERTSK 147
+ L S++K V + E+ S+
Sbjct: 281 RVDSLPASDDKDLNVATKQCVPEKVSE 307
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 111 bits (277), Expect = 7e-25
Identities = 69/162 (42%), Positives = 99/162 (61%), Gaps = 5/162 (3%)
Query: 86 QKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERT 145
Q + K ++ A ++ N + S Q+ + E+ L+ E ++E K++
Sbjct: 785 QDQILTSKQKELEMARKKMNSEISHRHQKEKDLFHEDC-MLQEEIALLRLEIDTIKNQNK 843
Query: 146 SKGKK---DIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKEN 202
K KK DIE VKE ND+LQ+ IKLN +TLT+T+ QY QLN+L EN +L S+LE
Sbjct: 844 QKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETILQYSGQLNNLTAENKILNSELENGK 903
Query: 203 QNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQ 244
QN+ERLE E+ES+ RLAAA+ +CDQS +T RDL+L QR +
Sbjct: 904 QNQERLEIEMESYRCRLAAAVRDCDQS-QTARDLKLDFQRTR 944
Score = 39.7 bits (91), Expect = 0.003
Identities = 18/32 (56%), Positives = 28/32 (87%), Gaps = 1/32 (3%)
Query: 104 KNEQTSKAEQEVQVTSEEEQEKLES-ENKQPQ 134
+N+++ +AEQ+ ++TSEEEQE+L+ ENKQPQ
Sbjct: 215 ENKESKEAEQDSELTSEEEQERLKGCENKQPQ 246
Score = 33.1 bits (74), Expect = 0.24
Identities = 42/182 (23%), Positives = 78/182 (42%), Gaps = 23/182 (12%)
Query: 49 EKLPSHHVNTEVLNKDTEVLNKDANTPLLLAIV--CKTQQKPTMEMKDSVV--KKAIERK 104
E +PS ++ L+ + EVL + AI C+T QK ++K VV K +ER
Sbjct: 1132 ETVPSRCLH---LDAENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERN 1188
Query: 105 NEQTSKAEQEVQVTSEEEQEKLESE--------NKQPQVEE---ARKKHERTSKGKKDIE 153
+ KAE + E ++++E + KQ V + + + T+ K +E
Sbjct: 1189 MLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQLVQLREDNTTSIKTQME 1248
Query: 154 I-VKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEV 212
+ +K++ ++ IK + KT ++ +L E ++ L E + AEV
Sbjct: 1249 LTIKDLESEISR-IKTSQADFNKTEL---ERYKELYLEEVKVRESLSNELSRTNEMIAEV 1304
Query: 213 ES 214
+
Sbjct: 1305 ST 1306
Score = 30.0 bits (66), Expect = 2.0
Identities = 37/173 (21%), Positives = 72/173 (41%), Gaps = 21/173 (12%)
Query: 83 KTQQKPTMEMKDSVVKKAIERKNEQTSKAEQE-VQVTSEEEQEKLESENKQPQVEEA--- 138
K Q P + DS+ I ++ + S + E + E+ + + + P++++
Sbjct: 585 KNQIYPEADFADSMEPSEIASEDCELSHSVYENFMLLIEQLRMEYKDSASLPRIQDTFCL 644
Query: 139 -------RKKH--ERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKT 189
+ H + T K K+ +V + ++L ET KT Q Q + +
Sbjct: 645 CEHLLKLKNNHCDQLTVKLKQMENMVSVLQNELSET--------KKTKLQLELQKIEWEK 696
Query: 190 ENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQR 242
E L+ L++EN+ K + +L EC + V+TK+ L+ L+R
Sbjct: 697 ELYDLRLALKQENEEKRNADMLYNKDSEQLRIKEEECGKVVETKQQLKWNLRR 749
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 110 bits (274), Expect = 2e-24
Identities = 71/170 (41%), Positives = 99/170 (58%), Gaps = 6/170 (3%)
Query: 83 KTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKH 142
K Q + T+ ++D +K N+ + E E + E L+ E ++E A KH
Sbjct: 1046 KQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCM--LKKEIAMLKLEVATLKH 1103
Query: 143 ERTSKGKK---DIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLE 199
+ K K DI+I++E N +LQ T+KL KT+TK SQY +QL L ENTML SKL
Sbjct: 1104 QHQVKENKYFEDIKILQEKNAELQMTLKLKQKTVTKRASQYREQLKVLTAENTMLTSKL- 1162
Query: 200 KENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQDVSLQ 249
KE Q+KE LE E+ES H RLA+A+ + DQSV ++++ ELA A D LQ
Sbjct: 1163 KEKQDKEILETEIESHHPRLASALQDHDQSVTSRKNQELAFHSAGDAPLQ 1212
Score = 71.6 bits (174), Expect = 6e-13
Identities = 39/85 (45%), Positives = 53/85 (62%), Gaps = 7/85 (8%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PLMKA+ C+ E C IL++ G + + +DVY N ALHYAVY+EN L+ L S+
Sbjct: 109 PLMKALQCEREACANILIDAGADLNYVDVYGNTALHYAVYSENLLMVATLLSY------- 161
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQ 86
EV NK + TPLLLAI +++Q
Sbjct: 162 GAVIEVQNKASLTPLLLAIQKRSKQ 186
Score = 36.6 bits (83), Expect = 0.021
Identities = 19/55 (34%), Positives = 31/55 (56%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKK 141
KP +EM+ +V KA E KNEQT +A Q S+++ ++ S + + E +K
Sbjct: 533 KPAVEMQKTVPNKAFELKNEQTLRAAQMFPSESKQKDDEENSWDSESPCETVSQK 587
Score = 34.7 bits (78), Expect = 0.081
Identities = 38/175 (21%), Positives = 74/175 (42%), Gaps = 63/175 (36%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEV-----------------------QVTSEEEQ 123
+P EM++SV K +E KN+QT +A+ Q+T++ EQ
Sbjct: 917 EPATEMQNSVPNKGLEWKNKQTLRADSTTLSKILDALPSCERGRELKKDNCEQITAKMEQ 976
Query: 124 EK----------LESENKQPQVEEARKKHERT-----------SKGKKDIEIVKE----- 157
K E++ + Q+E + K E+ + +++++I+KE
Sbjct: 977 TKNKFCVLQKELSEAKEIKSQLENQKAKWEQELCSVRLTLNQEEEKRRNVDILKEKIRPE 1036
Query: 158 --------MNDDLQETIKLNG---KTLTKTVSQYG---QQLNDLKTENTMLKSKL 198
+ L++T+++ K++T ++Q + NDL EN MLK ++
Sbjct: 1037 EQLRKKLEVKQQLEQTLRIQDIELKSVTSNLNQVSHTHESENDLFHENCMLKKEI 1091
Score = 34.3 bits (77), Expect = 0.11
Identities = 46/198 (23%), Positives = 76/198 (38%), Gaps = 52/198 (26%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEVQV-----------TSEEEQEKLESENKQPQV 135
KPT MK S+ KA+E K+ +T KAE V T + K+E +
Sbjct: 771 KPTCGMKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTTK 830
Query: 136 EEARKKHERTSKGKKDIEIVKEMNDD---LQETIKLNGKTLTKTVSQ------------- 179
E A K T + ++DI I++ D T +L K TK+ S
Sbjct: 831 EGATK--TVTGQQERDIGIIERAPQDQTNKMPTSELGRKEDTKSTSDSEIISVSDTQNYE 888
Query: 180 ---YGQQLNDLKTENTMLKSKLEK-------------------ENQNKERLEAEVESFHA 217
++KT N ++ EK E +NK+ L A+ + +
Sbjct: 889 CLPEATYQKEIKTTNGKIEESPEKPSHFEPATEMQNSVPNKGLEWKNKQTLRADSTTL-S 947
Query: 218 RLAAAISECDQSVKTKRD 235
++ A+ C++ + K+D
Sbjct: 948 KILDALPSCERGRELKKD 965
Score = 32.3 bits (72), Expect = 0.40
Identities = 47/201 (23%), Positives = 79/201 (39%), Gaps = 38/201 (18%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAE-------------QEVQVTSEEEQEKLESENKQP 133
KPT K S+ KA+E K+ +T KAE ++V + ++ + K K
Sbjct: 652 KPTCGRKVSLPNKALELKDRETLKAESPDNDGLLKPTCGRKVSLPNKALELKDRETFKAA 711
Query: 134 QVEEARKKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTM 193
Q+ + K + + D E E LQ + L T K +L + ++ +
Sbjct: 712 QMFPSESKQKDDEENSWDFESFLETL--LQNDVCLPKATHQKEFDTLSGKLEESPDKDGL 769
Query: 194 LK----SKLEKEN-----QNKERLEAE----VESFHARLAAAISECDQSVKTKRDLELAL 240
LK K+ N +++E +AE VES + +E QS K + D L
Sbjct: 770 LKPTCGMKISLPNKALELKDRETFKAEDVSSVESTFSLFGKPTTENSQSTKVEEDFNLTT 829
Query: 241 ----------QRAQDVSLQER 251
Q+ +D+ + ER
Sbjct: 830 KEGATKTVTGQQERDIGIIER 850
>gi|239741684 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
Length = 1524
Score = 109 bits (272), Expect = 3e-24
Identities = 63/138 (45%), Positives = 88/138 (63%), Gaps = 8/138 (5%)
Query: 116 QVTSEEEQEKLESENKQPQVEEARKKHERTS--------KGKKDIEIVKEMNDDLQETIK 167
QV+ +E+E L EN+ Q E AR + E+ + K KD EIVK ++DLQ+ +K
Sbjct: 1106 QVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK 1165
Query: 168 LNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECD 227
NG+TL KT++ Y QL L ENT L+SKLEK+ ++++RLE E++S+H RL AA + D
Sbjct: 1166 RNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHD 1225
Query: 228 QSVKTKRDLELALQRAQD 245
QS +KRD ELA Q D
Sbjct: 1226 QSHSSKRDQELAFQGTVD 1243
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/191 (25%), Positives = 86/191 (45%), Gaps = 32/191 (16%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTS-KAEQEVQVTSEEEQEKLES-ENKQPQVEEARKKHER 144
K T+E K+SV+ A + K+ QTS AEQ++++ SE EQ++LE EN QPQV+ +
Sbjct: 877 KATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDD 936
Query: 145 TSKGKKDIEIVKEMNDDL------------QETIKLNG--------------KTLTKTVS 178
+ + V E D L Q +K K L K
Sbjct: 937 LDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKD 996
Query: 179 QYGQQL----NDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKR 234
+ +QL LK + ++L+ ++ ++ + K +L+ E+ L + Q K +R
Sbjct: 997 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRR 1056
Query: 235 DLELALQRAQD 245
++E Q+ ++
Sbjct: 1057 NVEEVHQKVRE 1067
Score = 31.6 bits (70), Expect = 0.69
Identities = 30/162 (18%), Positives = 71/162 (43%), Gaps = 17/162 (10%)
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
++D + K L I C + Q + +++ ++ +E++ E + E E+Q
Sbjct: 1157 HEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ----- 1211
Query: 122 EQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDD----LQETIKLNGKTLTKTV 177
+ ++ AR H+++ K+D E+ + D LQE + + L+ +
Sbjct: 1212 --------SYHCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQL 1263
Query: 178 SQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARL 219
S+ + LKTE L+++ E +++E++ +++
Sbjct: 1264 SKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQM 1305
>gi|169163827 PREDICTED: similar to UPF0634 protein KIAA1641 [Homo
sapiens]
Length = 475
Score = 108 bits (270), Expect = 4e-24
Identities = 63/138 (45%), Positives = 85/138 (61%), Gaps = 8/138 (5%)
Query: 116 QVTSEEEQEKLESENKQPQVEEAR--------KKHERTSKGKKDIEIVKEMNDDLQETIK 167
QV+ +E+E L EN+ Q E AR K K KD EIVK ++DLQ+ +K
Sbjct: 156 QVSETDEKEDLLHENRLMQDEIARLRLDTDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK 215
Query: 168 LNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECD 227
NG+TL KT++ Y QL L ENT L+SKLEK+ ++++RLE E++S+H RL AA + D
Sbjct: 216 RNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYHCRLNAARCDHD 275
Query: 228 QSVKTKRDLELALQRAQD 245
QS +KRD ELA Q D
Sbjct: 276 QSHSSKRDQELAFQGTVD 293
Score = 32.0 bits (71), Expect = 0.53
Identities = 36/201 (17%), Positives = 85/201 (42%), Gaps = 36/201 (17%)
Query: 42 NENTLLAEKLPSHHVNTEVLN---------KDTEVLN----------KDANTPLLLAIVC 82
+EN L+ +++ ++T+ + KD E++ K L I C
Sbjct: 168 HENRLMQDEIARLRLDTDTIKNQNLEKKYLKDFEIVKRKHEDLQKALKRNGETLAKTIAC 227
Query: 83 KTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKH 142
+ Q + +++ ++ +E++ E + E E+Q + ++ AR H
Sbjct: 228 YSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ-------------SYHCRLNAARCDH 274
Query: 143 ERTSKGKKDIEIVKEMNDD----LQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKL 198
+++ K+D E+ + D LQE + + L+ +S+ + LKTE L
Sbjct: 275 DQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQLSKAESKSRVLKTELHYTGEAL 334
Query: 199 EKENQNKERLEAEVESFHARL 219
+++ E +++E++ +++
Sbjct: 335 KEKALVFEHVQSELKQKQSQM 355
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 106 bits (264), Expect = 2e-23
Identities = 62/138 (44%), Positives = 87/138 (63%), Gaps = 8/138 (5%)
Query: 116 QVTSEEEQEKLESENKQPQVEEARKKHERTS--------KGKKDIEIVKEMNDDLQETIK 167
QV+ +E+E L EN+ Q E AR + E+ + K KD EIVK ++DLQ+ +K
Sbjct: 703 QVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK 762
Query: 168 LNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECD 227
NG+TL KT++ Y QL L ENT L+SKLEK+ ++++RLE E++S+ RL AA + D
Sbjct: 763 RNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQSYRCRLNAARCDHD 822
Query: 228 QSVKTKRDLELALQRAQD 245
QS +KRD ELA Q D
Sbjct: 823 QSHSSKRDQELAFQGTVD 840
Score = 53.9 bits (128), Expect = 1e-07
Identities = 50/191 (26%), Positives = 85/191 (44%), Gaps = 32/191 (16%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTS-KAEQEVQVTSEEEQEKLES-ENKQPQVEEARKKHER 144
K T+E KDSV+ A + K QTS AEQ++++ SE EQ++LE EN QPQV+ +
Sbjct: 474 KATIENKDSVLNTATKMKEVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDD 533
Query: 145 TSKGKKDIEIVKEMNDDL------------QETIKLNG--------------KTLTKTVS 178
+ + V E D L Q +K K L K
Sbjct: 534 LDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKNTFCLWKRLIKLKD 593
Query: 179 QYGQQL----NDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKR 234
+ +QL LK + ++L+ ++ ++ + K +L+ E+ L + Q K +R
Sbjct: 594 NHCEQLRVKIRKLKNKASVLQKRISEKEEIKSQLKHEILELEKELCSLRFAIQQEKKKRR 653
Query: 235 DLELALQRAQD 245
++E Q+ ++
Sbjct: 654 NVEELHQKVRE 664
Score = 32.0 bits (71), Expect = 0.53
Identities = 30/162 (18%), Positives = 72/162 (44%), Gaps = 17/162 (10%)
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
++D + K L I C + Q + +++ ++ +E++ E + E E+Q
Sbjct: 754 HEDLQKALKRNGETLAKTIACYSGQLAALTDENTTLRSKLEKQRESRQRLETEMQ----- 808
Query: 122 EQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDD----LQETIKLNGKTLTKTV 177
+ + ++ AR H+++ K+D E+ + D LQE + + L+ +
Sbjct: 809 --------SYRCRLNAARCDHDQSHSSKRDQELAFQGTVDKCRHLQENLNSHVLILSLQL 860
Query: 178 SQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARL 219
S+ + LKTE L+++ E +++E++ +++
Sbjct: 861 SKAESKSRVLKTELHYTGEALKEKALVFEHVQSELKQKQSQM 902
>gi|239747793 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 868
Score = 102 bits (253), Expect = 4e-22
Identities = 60/138 (43%), Positives = 86/138 (62%), Gaps = 8/138 (5%)
Query: 116 QVTSEEEQEKLESENKQPQVEEARKKHERTS--------KGKKDIEIVKEMNDDLQETIK 167
QV+ +E+E L EN+ Q E AR + E+ + K KD EIVK ++DLQ+ +K
Sbjct: 450 QVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK 509
Query: 168 LNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECD 227
N +TL +T++ Y QL L ENT L+SKLEK+ ++ +RLE E++S+ RL AA+ + D
Sbjct: 510 RNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHD 569
Query: 228 QSVKTKRDLELALQRAQD 245
QS +KRD ELA Q D
Sbjct: 570 QSHSSKRDQELAFQGTVD 587
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/191 (26%), Positives = 86/191 (45%), Gaps = 32/191 (16%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTS-KAEQEVQVTSEEEQEKLES-ENKQPQVEEARKKHER 144
K T+E K+SV+ A + K+ QTS AEQ++++ SE EQ++LE EN QPQV+ +
Sbjct: 221 KATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDD 280
Query: 145 TSKGKKDIEIVKEMNDDL------------QETIKLNG--------------KTLTKTVS 178
+ + V E D L Q +K K LT+
Sbjct: 281 LDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKD 340
Query: 179 QYGQQL----NDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKR 234
+ +QL LK + ++L+ +L ++ + K +L+ E L + Q K +R
Sbjct: 341 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRR 400
Query: 235 DLELALQRAQD 245
++E Q+ ++
Sbjct: 401 NVEELHQKVRE 411
Score = 27.7 bits (60), Expect = 9.9
Identities = 28/162 (17%), Positives = 71/162 (43%), Gaps = 17/162 (10%)
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
++D + K L I C + Q + +++ ++ +E++ E + E E+Q
Sbjct: 501 HEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ----- 555
Query: 122 EQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDD----LQETIKLNGKTLTKTV 177
+ + ++ A H+++ K+D E+ + D LQE + + L+ +
Sbjct: 556 --------SYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQL 607
Query: 178 SQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARL 219
S+ + L+TE L+++ E +++E++ +++
Sbjct: 608 SKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQM 649
>gi|239741673 PREDICTED: protein immuno-reactive with anti-PTH
polyclonal antibodies [Homo sapiens]
Length = 1430
Score = 102 bits (253), Expect = 4e-22
Identities = 60/138 (43%), Positives = 86/138 (62%), Gaps = 8/138 (5%)
Query: 116 QVTSEEEQEKLESENKQPQVEEARKKHERTS--------KGKKDIEIVKEMNDDLQETIK 167
QV+ +E+E L EN+ Q E AR + E+ + K KD EIVK ++DLQ+ +K
Sbjct: 1012 QVSETDEKEDLLHENRLMQDEIARLRLEKDTIKNQNLEKKYLKDFEIVKRKHEDLQKALK 1071
Query: 168 LNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECD 227
N +TL +T++ Y QL L ENT L+SKLEK+ ++ +RLE E++S+ RL AA+ + D
Sbjct: 1072 RNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQSYRCRLNAALCDHD 1131
Query: 228 QSVKTKRDLELALQRAQD 245
QS +KRD ELA Q D
Sbjct: 1132 QSHSSKRDQELAFQGTVD 1149
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/191 (26%), Positives = 86/191 (45%), Gaps = 32/191 (16%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTS-KAEQEVQVTSEEEQEKLES-ENKQPQVEEARKKHER 144
K T+E K+SV+ A + K+ QTS AEQ++++ SE EQ++LE EN QPQV+ +
Sbjct: 783 KATIENKNSVLNTATKMKDVQTSTPAEQDLEMASEGEQKRLEEYENNQPQVKNQIHSRDD 842
Query: 145 TSKGKKDIEIVKEMNDDL------------QETIKLNG--------------KTLTKTVS 178
+ + V E D L Q +K K LT+
Sbjct: 843 LDDIIQSSQTVSEDGDSLCCNCKNVILLIDQHEMKCKDCVHLLKIKKTFCLCKRLTELKD 902
Query: 179 QYGQQL----NDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKR 234
+ +QL LK + ++L+ +L ++ + K +L+ E L + Q K +R
Sbjct: 903 NHCEQLRVKIRKLKNKASVLQKRLSEKEEIKSQLKHETLELEKELCSLRFAIQQEKKKRR 962
Query: 235 DLELALQRAQD 245
++E Q+ ++
Sbjct: 963 NVEELHQKVRE 973
Score = 27.7 bits (60), Expect = 9.9
Identities = 28/162 (17%), Positives = 71/162 (43%), Gaps = 17/162 (10%)
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
++D + K L I C + Q + +++ ++ +E++ E + E E+Q
Sbjct: 1063 HEDLQKALKRNEETLAETIACYSGQLAALTDENTTLRSKLEKQRESGQRLETEMQ----- 1117
Query: 122 EQEKLESENKQPQVEEARKKHERTSKGKKDIEIVKEMNDD----LQETIKLNGKTLTKTV 177
+ + ++ A H+++ K+D E+ + D LQE + + L+ +
Sbjct: 1118 --------SYRCRLNAALCDHDQSHSSKRDQELAFQGTVDKCCHLQENLNSHVLILSLQL 1169
Query: 178 SQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARL 219
S+ + L+TE L+++ E +++E++ +++
Sbjct: 1170 SKAESKFRVLETELHYTGEALKEKALVFEHVQSELKQKQSQM 1211
>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
Length = 1341
Score = 101 bits (252), Expect = 5e-22
Identities = 69/172 (40%), Positives = 96/172 (55%), Gaps = 6/172 (3%)
Query: 83 KTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKH 142
K Q + + ++D +K N+ + E E + E L+ E ++E A KH
Sbjct: 1010 KQQLEQALRIQDIELKSVESNLNQVSHTHENENYLLHENCM--LKKEIAMLKLEIATLKH 1067
Query: 143 ERTSKGKK---DIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLE 199
+ K K DI+I+KE N +LQ T+KL ++LTK SQY QL L ENTML SKL
Sbjct: 1068 QYQEKENKYFEDIKILKEKNAELQMTLKLKEESLTKRASQYSGQLKVLIAENTMLTSKL- 1126
Query: 200 KENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQRAQDVSLQER 251
KE Q+KE LEAE+ES H RLA+A+ + DQ V +++ E A A D LQ +
Sbjct: 1127 KEKQDKEILEAEIESHHPRLASAVQDHDQIVTSRKSQEPAFHIAGDACLQRK 1178
Score = 71.2 bits (173), Expect = 8e-13
Identities = 39/85 (45%), Positives = 53/85 (62%), Gaps = 7/85 (8%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PLMKA+ C +E C IL++ G + +L+DVY N ALHYAVY+E + KL SH
Sbjct: 53 PLMKALQCHQEACANILIDSGADINLVDVYGNTALHYAVYSEILSVVAKLLSH------- 105
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQ 86
EV NK + TPLLL+I +++Q
Sbjct: 106 GAVIEVHNKASLTPLLLSITKRSEQ 130
Score = 48.1 bits (113), Expect = 7e-06
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 37/183 (20%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHE--R 144
+P +EM+ SV KA+E KNEQT +A+Q SE+KQ +VEE E R
Sbjct: 825 EPAIEMQKSVPNKALELKNEQTLRADQ-----------MFPSESKQKKVEENSWDSESLR 873
Query: 145 TSKGKKDIEIVKEMNDDLQETIKLNGK-----TLTKTV-----------------SQYGQ 182
+ +KD+ + K + +E K++GK +L+K + Q
Sbjct: 874 ETVSQKDVCVPKATHQ--KEMDKISGKLEDSTSLSKILDTVHSCERARELQKDHCEQRTG 931
Query: 183 QLNDLKTENTMLKSKLEKENQNKERLEAEVESFHARLAAAISECDQSVKTKRDLELALQR 242
++ +K + +LK KL + + K +LE + + L + +Q + +R+ ++ ++
Sbjct: 932 KMEQMKKKFCVLKKKLSEAKEIKSQLENQKVKWEQELCSVRLTLNQEEEKRRNADILNEK 991
Query: 243 AQD 245
++
Sbjct: 992 IRE 994
Score = 41.2 bits (95), Expect = 9e-04
Identities = 31/87 (35%), Positives = 46/87 (52%), Gaps = 15/87 (17%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTS 146
+P +EM+ SV KA+E KNEQT +A+ E L SE+KQ EE+ E
Sbjct: 706 EPAIEMQKSVPNKALELKNEQTLRAD-----------EILPSESKQKDYEESSWDSESLC 754
Query: 147 K--GKKDIEIVKEMNDDLQETIKLNGK 171
+ +KD+ + K + +E K+NGK
Sbjct: 755 ETVSQKDVCLPKATHQ--KEIDKINGK 779
Score = 39.3 bits (90), Expect = 0.003
Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTS 146
KP +EM++SV KA E KNEQT +A+ S+++ + S + + E +K
Sbjct: 468 KPAIEMQNSVPNKAFELKNEQTLRADPMFPPESKQKDYEENSWDSESLCETVSQKDVCLP 527
Query: 147 KGKKDIEIVKEMNDDLQETIKLNG 170
K EI K +N L+E+ +G
Sbjct: 528 KATHQKEIDK-INGKLEESPNKDG 550
Score = 38.9 bits (89), Expect = 0.004
Identities = 31/87 (35%), Positives = 44/87 (50%), Gaps = 15/87 (17%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTS 146
+P EM+ SV KA+E KNEQT +A+ E L SE+KQ EE E
Sbjct: 587 EPATEMQKSVPNKALELKNEQTLRAD-----------EILPSESKQKDYEENSWDTESLC 635
Query: 147 K--GKKDIEIVKEMNDDLQETIKLNGK 171
+ +KD+ + K + +E K+NGK
Sbjct: 636 ETVSQKDVCLPKAAHQ--KEIDKINGK 660
Score = 32.3 bits (72), Expect = 0.40
Identities = 36/123 (29%), Positives = 52/123 (42%), Gaps = 8/123 (6%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLES-------ENKQPQVEEAR 139
K T MK S+ KA+E K+ QT KAE + ++ E +++ E K Q A
Sbjct: 553 KATCGMKVSIPTKALELKDMQTFKAEPPGKPSAFEPATEMQKSVPNKALELKNEQTLRAD 612
Query: 140 KKHERTSKGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLE 199
+ SK +KD E + L ET+ L K Q + K E + +K L
Sbjct: 613 EILPSESK-QKDYEENSWDTESLCETVSQKDVCLPKAAHQKEIDKINGKLEGSPVKDGLL 671
Query: 200 KEN 202
K N
Sbjct: 672 KAN 674
Score = 28.1 bits (61), Expect = 7.6
Identities = 32/126 (25%), Positives = 56/126 (44%), Gaps = 7/126 (5%)
Query: 87 KPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEEEQEKLESENKQPQVEEARKKHERTS 146
K MK S+ KA+E + QT KAE + ++ E +++ +E K+E+T
Sbjct: 672 KANCGMKVSIPTKALELMDMQTFKAEPPEKPSAFEPAIEMQKSVPNKALE---LKNEQTL 728
Query: 147 KGKKDIEIVKEMNDDLQETIKLNGKTLTKTVSQYGQQLNDL--KTENTMLKSKLEKENQN 204
+ + + + D E + ++L +TVSQ L + E + KLE+ N
Sbjct: 729 RADEILPSESKQKD--YEESSWDSESLCETVSQKDVCLPKATHQKEIDKINGKLEESPDN 786
Query: 205 KERLEA 210
L+A
Sbjct: 787 DGFLKA 792
>gi|50897294 POTE ankyrin domain family, member A isoform 1 [Homo
sapiens]
Length = 452
Score = 94.4 bits (233), Expect = 9e-20
Identities = 66/233 (28%), Positives = 117/233 (50%), Gaps = 38/233 (16%)
Query: 3 LMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLN 62
L+KAV CQE+ C ++LL+ GT+P+L D+Y N ALHYAVYNE+ L+A+ L +
Sbjct: 136 LIKAVQCQEDECALMLLQHGTDPNLPDMYGNTALHYAVYNEDKLMAKTL-------LLYG 188
Query: 63 KDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIER------------------K 104
D E NK TPLLLA+ + Q+ +K A++R
Sbjct: 189 ADIESKNKGGLTPLLLAVHGQKQRMVKFLIKKKANLNALDRFGRICQLLSDYKENQMPNN 248
Query: 105 NEQTSKAEQEVQVTSEEEQEKLE-SENKQPQVEEARKKHERTSKGKKDIEIVKEMNDDLQ 163
+ S EQ++++TSEEE ++L+ SEN Q HE+ + ++ +I K+ + +++
Sbjct: 249 SSGNSNPEQDLKLTSEEEPQRLKGSENSQ---------HEKVT---QEPDINKDCDREVE 296
Query: 164 ETIKLNGKTLTKTVSQYGQQLNDLKTENTMLKSKLEKENQNKERLEAEVESFH 216
E ++ +G + ++ + ++++N++ E+E +H
Sbjct: 297 EEMQKHGSNNVGLSENLTDGAAAGNGDGGLVPQRKSRKHENQQFPNTEIEEYH 349
Score = 30.4 bits (67), Expect = 1.5
Identities = 51/250 (20%), Positives = 101/250 (40%), Gaps = 47/250 (18%)
Query: 2 PLMKAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVL 61
PL+ AVH Q++ V L++ N + +D + + Y EN ++P++
Sbjct: 201 PLLLAVHGQKQRMVKFLIKKKANLNALDRFGRICQLLSDYKEN-----QMPNNSSGNSNP 255
Query: 62 NKDTEVLNKDANTPLLLAIVCKTQQKPTMEMKDSVVKKAIERKNEQTSKAEQEVQVTSEE 121
+D ++ +++ P L +Q + + D + K +R+ E+ + V E
Sbjct: 256 EQDLKLTSEE--EPQRLKGSENSQHEKVTQEPD--INKDCDREVEEEMQKHGSNNVGLSE 311
Query: 122 -----------------EQEKLESENKQ---PQVEE---ARKKHERTSKGKKDIEIVKEM 158
+++ + EN+Q ++EE KK +K K I V +
Sbjct: 312 NLTDGAAAGNGDGGLVPQRKSRKHENQQFPNTEIEEYHRPEKKSNEKNKVKSQIHSVDNL 371
Query: 159 ND---------DLQETIKLNGKTLTKTVSQYGQQLND----LKTENTMLKSK--LEKENQ 203
+D + + + N +T T + Q ND K ++ ++ + LE +N
Sbjct: 372 DDITWPSEIASEDYDLLFSNYETFTLLIEQLKMDFNDSASLSKIQDAVISEEHLLELKNS 431
Query: 204 NKERLEAEVE 213
+ E+L EVE
Sbjct: 432 HYEQLTVEVE 441
>gi|239755970 PREDICTED: FLJ46358 protein [Homo sapiens]
Length = 227
Score = 85.1 bits (209), Expect = 5e-17
Identities = 41/59 (69%), Positives = 47/59 (79%)
Query: 5 KAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLNK 63
+AVHCQEE C IILLE G NP+L DVYSN AL YAVY+E+T LA+KL SH NTE L+K
Sbjct: 168 QAVHCQEEACAIILLERGANPNLKDVYSNTALQYAVYSESTSLAKKLLSHDANTEALDK 226
>gi|239750493 PREDICTED: FLJ46358 protein [Homo sapiens]
Length = 227
Score = 85.1 bits (209), Expect = 5e-17
Identities = 41/59 (69%), Positives = 47/59 (79%)
Query: 5 KAVHCQEEICVIILLECGTNPDLMDVYSNNALHYAVYNENTLLAEKLPSHHVNTEVLNK 63
+AVHCQEE C IILLE G NP+L DVYSN AL YAVY+E+T LA+KL SH NTE L+K
Sbjct: 168 QAVHCQEEACAIILLERGANPNLKDVYSNTALQYAVYSESTSLAKKLLSHDANTEALDK 226
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.123 0.321
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,417,141
Number of Sequences: 37866
Number of extensions: 366979
Number of successful extensions: 9193
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 583
Number of HSP's successfully gapped in prelim test: 777
Number of HSP's that attempted gapping in prelim test: 3790
Number of HSP's gapped (non-prelim): 4200
length of query: 252
length of database: 18,247,518
effective HSP length: 100
effective length of query: 152
effective length of database: 14,460,918
effective search space: 2198059536
effective search space used: 2198059536
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.