Search of human proteins with 110618236

Search of human proteins with 110618236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]
         (187 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]          394   e-110
gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]          354   2e-98
gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]          345   1e-95
gi|4502649 CD1D antigen precursor [Homo sapiens]                      195   2e-50
gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]          187   3e-48
gi|110618224 CD1A antigen precursor [Homo sapiens]                    184   3e-47
gi|4502645 CD1B antigen precursor [Homo sapiens]                      182   1e-46
gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]          177   5e-45
gi|110618227 CD1C antigen precursor [Homo sapiens]                    163   9e-41
gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]          137   4e-33
gi|4504417 major histocompatibility complex, class I-related [Ho...    50   9e-07
gi|89063265 PREDICTED: similar to MHC class I antigen [Homo sapi...    50   1e-06
gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]                 49   3e-06
gi|24797076 major histocompatibility complex, class II, DP beta ...    49   3e-06
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s...    47   7e-06
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa...    47   7e-06
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa...    47   7e-06
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa...    47   7e-06
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa...    47   7e-06
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa...    47   7e-06
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa...    47   7e-06
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap...    47   7e-06
gi|239740855 PREDICTED: similar to major histocompatibility comp...    47   7e-06
gi|239740853 PREDICTED: similar to major histocompatibility comp...    47   7e-06
gi|239740920 PREDICTED: similar to major histocompatibility comp...    47   1e-05
gi|239740918 PREDICTED: similar to major histocompatibility comp...    47   1e-05
gi|17986005 major histocompatibility complex, class II, DR beta ...    46   2e-05
gi|52630344 major histocompatibility complex, class II, DR beta ...    46   2e-05
gi|239758092 PREDICTED: similar to HLA class II histocompatibili...    46   2e-05
gi|239758090 PREDICTED: major histocompatibility complex, class ...    46   2e-05

>gi|110618236 CD1E antigen isoform e precursor [Homo sapiens]
          Length = 187

 Score =  394 bits (1012), Expect = e-110
 Identities = 187/187 (100%), Positives = 187/187 (100%)

Query: 1   MLLLFLLFEGLCCPGENTAVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ 60
           MLLLFLLFEGLCCPGENTAVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ
Sbjct: 1   MLLLFLLFEGLCCPGENTAVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ 60

Query: 61  EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLI 120
           EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLI
Sbjct: 61  EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLI 120

Query: 121 LICLTVIVTLVILVVVDSRLKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWK 180
           LICLTVIVTLVILVVVDSRLKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWK
Sbjct: 121 LICLTVIVTLVILVVVDSRLKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWK 180

Query: 181 TRLNQLW 187
           TRLNQLW
Sbjct: 181 TRLNQLW 187


>gi|110618230 CD1E antigen isoform b precursor [Homo sapiens]
          Length = 376

 Score =  354 bits (909), Expect = 2e-98
 Identities = 168/168 (100%), Positives = 168/168 (100%)

Query: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
           VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY
Sbjct: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 268

Query: 80  LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 139
           LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR
Sbjct: 269 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 328

Query: 140 LKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 187
           LKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 329 LKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 376



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%)

Query: 1  MLLLFLLFEGLCCPGENTAVKPEA 24
          MLLLFLLFEGLCCPGENTA  P+A
Sbjct: 1  MLLLFLLFEGLCCPGENTAA-PQA 23


>gi|110618240 CD1E antigen isoform a precursor [Homo sapiens]
          Length = 388

 Score =  345 bits (886), Expect = 1e-95
 Identities = 168/180 (93%), Positives = 168/180 (93%), Gaps = 12/180 (6%)

Query: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
           VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY
Sbjct: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 268

Query: 80  LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 139
           LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR
Sbjct: 269 LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 328

Query: 140 LKKQ------------SPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 187
           LKKQ            SPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 329 LKKQSSNKNILSPHTPSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 388



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%)

Query: 1  MLLLFLLFEGLCCPGENTAVKPEA 24
          MLLLFLLFEGLCCPGENTA  P+A
Sbjct: 1  MLLLFLLFEGLCCPGENTAA-PQA 23


>gi|4502649 CD1D antigen precursor [Homo sapiens]
          Length = 335

 Score =  195 bits (495), Expect = 2e-50
 Identities = 92/127 (72%), Positives = 106/127 (83%), Gaps = 2/127 (1%)

Query: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
           VKP+AWLS GPSPGPGRL LVCHVSGFYPKPVWV WMRGEQEQ+GTQ GD+LPNADETWY
Sbjct: 203 VKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWY 262

Query: 80  LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVV--D 137
           LRATLDV AGEAAGLSCRVKHSSL G D++++WGG    + LI L V+  L+ L++V   
Sbjct: 263 LRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTSMGLIALAVLACLLFLLIVGFT 322

Query: 138 SRLKKQS 144
           SR K+Q+
Sbjct: 323 SRFKRQT 329


>gi|110618234 CD1E antigen isoform d precursor [Homo sapiens]
          Length = 321

 Score =  187 bits (476), Expect = 3e-48
 Identities = 102/168 (60%), Positives = 107/168 (63%), Gaps = 55/168 (32%)

Query: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
           VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMR                      
Sbjct: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMR---------------------- 246

Query: 80  LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 139
                                   GG+ + +        LI + + V  TLVILVVVDSR
Sbjct: 247 ------------------------GGYSIFL-------ILICLTVIV--TLVILVVVDSR 273

Query: 140 LKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 187
           LKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW
Sbjct: 274 LKKQSPVFLMGANTQDTKNSRHQFCLAQVSWIKNRVLKKWKTRLNQLW 321



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%)

Query: 1  MLLLFLLFEGLCCPGENTAVKPEA 24
          MLLLFLLFEGLCCPGENTA  P+A
Sbjct: 1  MLLLFLLFEGLCCPGENTAA-PQA 23


>gi|110618224 CD1A antigen precursor [Homo sapiens]
          Length = 327

 Score =  184 bits (468), Expect = 3e-47
 Identities = 87/115 (75%), Positives = 100/115 (86%), Gaps = 1/115 (0%)

Query: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
           VKPEAWLS GPSPGPG LQLVCHVSGFYPKPVWVMWMRGEQEQ+GTQRGD+LP+AD TWY
Sbjct: 202 VKPEAWLSHGPSPGPGHLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQRGDILPSADGTWY 261

Query: 80  LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILV 134
           LRATL+VAAGEAA LSCRVKHSSL G D++++W  +S    +I L VIV L++L+
Sbjct: 262 LRATLEVAAGEAADLSCRVKHSSLEGQDIVLYWEHHSSVGFII-LAVIVPLLLLI 315


>gi|4502645 CD1B antigen precursor [Homo sapiens]
          Length = 333

 Score =  182 bits (462), Expect = 1e-46
 Identities = 83/115 (72%), Positives = 98/115 (85%)

Query: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
           VKPEAWLS GPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQ+GTQ GD+LPNA+ TWY
Sbjct: 203 VKPEAWLSSGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQQGTQLGDILPNANWTWY 262

Query: 80  LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILV 134
           LRATLDVA GEAAGLSCRVKHSSL G D+I++W   +    ++   ++ +L++L+
Sbjct: 263 LRATLDVADGEAAGLSCRVKHSSLEGQDIILYWRNPTSIGSIVLAIIVPSLLLLL 317


>gi|110618238 CD1E antigen isoform f precursor [Homo sapiens]
          Length = 101

 Score =  177 bits (449), Expect = 5e-45
 Identities = 78/80 (97%), Positives = 80/80 (100%)

Query: 1  MLLLFLLFEGLCCPGENTAVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ 60
          MLLLFLLFEGLCCPGENTAVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ
Sbjct: 1  MLLLFLLFEGLCCPGENTAVKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQ 60

Query: 61 EQRGTQRGDVLPNADETWYL 80
          EQRGTQRGDVLPNADETW++
Sbjct: 61 EQRGTQRGDVLPNADETWWI 80


>gi|110618227 CD1C antigen precursor [Homo sapiens]
          Length = 333

 Score =  163 bits (412), Expect = 9e-41
 Identities = 79/123 (64%), Positives = 94/123 (76%), Gaps = 1/123 (0%)

Query: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
           V+PEAWLS  PS G G+L LVCH SGFYPKPVWV WMR EQEQ GT+ GD+LPNAD TWY
Sbjct: 204 VRPEAWLSSRPSLGSGQLLLVCHASGFYPKPVWVTWMRNEQEQLGTKHGDILPNADGTWY 263

Query: 80  LRATLDVAAGEAAGLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVVDSR 139
           L+  L+VA+ E AGLSCRV+HSSLGG D+I++W G+   +  I L VIV LVIL+V+   
Sbjct: 264 LQVILEVASEEPAGLSCRVRHSSLGGQDIILYW-GHHFSMNWIALVVIVPLVILIVLVLW 322

Query: 140 LKK 142
            KK
Sbjct: 323 FKK 325


>gi|110618232 CD1E antigen isoform c precursor [Homo sapiens]
          Length = 290

 Score =  137 bits (346), Expect = 4e-33
 Identities = 59/61 (96%), Positives = 61/61 (100%)

Query: 20  VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWY 79
           VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETW+
Sbjct: 209 VKPEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWW 268

Query: 80  L 80
           +
Sbjct: 269 I 269



 Score = 44.7 bits (104), Expect = 5e-05
 Identities = 21/24 (87%), Positives = 22/24 (91%), Gaps = 1/24 (4%)

Query: 1  MLLLFLLFEGLCCPGENTAVKPEA 24
          MLLLFLLFEGLCCPGENTA  P+A
Sbjct: 1  MLLLFLLFEGLCCPGENTAA-PQA 23


>gi|4504417 major histocompatibility complex, class I-related [Homo
           sapiens]
          Length = 341

 Score = 50.4 bits (119), Expect = 9e-07
 Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 4/104 (3%)

Query: 34  PGRLQLVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAA 92
           PG   L C   GFYP  +++ WM+ GE+  +    GD+LP+ D T+   A++++    + 
Sbjct: 215 PGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSN 274

Query: 93  GLSCRVKHSSLGGHDLIIHWGGYSIFLILICLTVIVTLVILVVV 136
             SC V+H    G  +++     S  + L+   V  ++V+++V+
Sbjct: 275 LYSCHVEHC---GVHMVLQVPQESETIPLVMKAVSGSIVLVIVL 315


>gi|89063265 PREDICTED: similar to MHC class I antigen [Homo
           sapiens]
          Length = 366

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 35/99 (35%), Positives = 52/99 (52%), Gaps = 6/99 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           L C   GFYP+ + + W R GE + +  +  +  P+ D T+   A L V +GE    +CR
Sbjct: 238 LRCWALGFYPEEISLTWQREGEDQTQDMELVETRPSGDGTFQKWAALVVPSGEEQRYTCR 297

Query: 98  VKHSSLGGHDLIIHW-GGYSIFLILICLTVIVTLVILVV 135
           V+H  L    L + W    + FLI   + +IV LV+LVV
Sbjct: 298 VQHEGL-QEPLTLRWEPPQTSFLI---MGIIVGLVLLVV 332


>gi|4502337 alpha-2-glycoprotein 1, zinc [Homo sapiens]
          Length = 298

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 30/91 (32%), Positives = 44/91 (48%), Gaps = 2/91 (2%)

Query: 22  PEAWLSCGPSPGPGRLQLVCHVSGFYPKPVWVMWMRGEQEQRGTQRGDVLPNADETWYLR 81
           P   ++   +PG  + +L C    FYP  + V W R  + Q    RGDVL N + T+   
Sbjct: 207 PSVVVTSHQAPGEKK-KLKCLAYDFYPGKIDVHWTRAGEVQEPELRGDVLHNGNGTYQSW 265

Query: 82  ATLDVAAGEAAGLSCRVKHSSLGGHDLIIHW 112
             + V   + A  SC V+HSSL    L++ W
Sbjct: 266 VVVAVPPQDTAPYSCHVQHSSL-AQPLVVPW 295


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 24/79 (30%), Positives = 43/79 (54%), Gaps = 2/79 (2%)

Query: 39  LVCHVSGFYPKPVWVMW-MRGEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVCHV+ FYP  + V W + G++E  G    +++ N D T+ +   L++   +    +C+
Sbjct: 142 LVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLEMTPQQGDVYTCQ 201

Query: 98  VKHSSLGGHDLIIHWGGYS 116
           V+H+SL    + + W   S
Sbjct: 202 VEHTSLDS-PVTVEWKAQS 219


>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
           sapiens]
          Length = 168

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 96
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 43  LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 102

Query: 97  RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQ 143
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+
Sbjct: 103 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 152


>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
           sapiens]
          Length = 325

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 96
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 200 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 259

Query: 97  RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQ 143
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+
Sbjct: 260 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 309


>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
           sapiens]
          Length = 246

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 96
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 121 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 180

Query: 97  RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQ 143
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+
Sbjct: 181 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 230


>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
           sapiens]
          Length = 260

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 96
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 135 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 194

Query: 97  RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQ 143
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+
Sbjct: 195 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 244


>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
           sapiens]
          Length = 334

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 96
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 209 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 268

Query: 97  RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQ 143
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+
Sbjct: 269 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 318


>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
           sapiens]
          Length = 256

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 96
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 131 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 190

Query: 97  RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQ 143
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+
Sbjct: 191 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 240


>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
           sapiens]
          Length = 242

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 96
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 117 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 176

Query: 97  RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQ 143
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+
Sbjct: 177 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 226


>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
           sapiens]
          Length = 348

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 30/111 (27%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQ--EQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSC 96
           L C    +YP+ + + W++ +Q  + +  +  DVLPN D T+    TL V  GE    +C
Sbjct: 223 LRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTC 282

Query: 97  RVKHSSLGGHDLIIHW----GGYSIFLILICLTVIVTLVILVVVDSRLKKQ 143
           +V+H  L    LI+ W     G  +  ++  + V V ++ + ++   L+K+
Sbjct: 283 QVEHPGL-DQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKR 332


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 39  LVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVC VSGFYP  + V W R G++E+ G     ++ N D T+     L+         +C+
Sbjct: 145 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQ 204

Query: 98  VKHSSLGGHDLIIHWGGYS 116
           V+H S+    L + W   S
Sbjct: 205 VEHPSVTS-PLTVEWSARS 222


>gi|239740853 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 26/79 (32%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 39  LVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVC VSGFYP  + V W R G++E+ G     ++ N D T+     L+         +C+
Sbjct: 144 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQ 203

Query: 98  VKHSSLGGHDLIIHWGGYS 116
           V+H S+    L + W   S
Sbjct: 204 VEHPSVTS-PLTVEWSARS 221


>gi|239740920 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
          Length = 261

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 17/106 (16%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQEQ-RGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVC V+ FYP  + V W R +QE+  G     ++ N D T+ +   L++        +C 
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCH 206

Query: 98  VKHSSLGGHDLIIHW---------------GGYSIFLILICLTVIV 128
           V+H SL  + +I+ W               GG+ + LI + L +I+
Sbjct: 207 VEHPSL-QNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLII 251


>gi|239740918 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
          Length = 281

 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 17/106 (16%)

Query: 39  LVCHVSGFYPKPVWVMWMRGEQEQ-RGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVC V+ FYP  + V W R +QE+  G     ++ N D T+ +   L++        +C 
Sbjct: 147 LVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCH 206

Query: 98  VKHSSLGGHDLIIHW---------------GGYSIFLILICLTVIV 128
           V+H SL  + +I+ W               GG+ + LI + L +I+
Sbjct: 207 VEHPSL-QNPIIVEWRAQSESAQSKMLSGIGGFVLGLIFLGLGLII 251


>gi|17986005 major histocompatibility complex, class II, DR beta 3
           precursor [Homo sapiens]
          Length = 266

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 39  LVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVC VSGFYP  + V W R G++E+ G     ++ N D T+     L+         +C+
Sbjct: 144 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQ 203

Query: 98  VKHSSLGGHDLIIHW 112
           V+H S+    L + W
Sbjct: 204 VEHPSVTS-ALTVEW 217


>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 39  LVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVC V+GFYP  + V W R G++E+ G     ++ N D T+     L+         +C+
Sbjct: 144 LVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQ 203

Query: 98  VKHSSLGGHDLIIHWGGYS 116
           V+H S+    L + W   S
Sbjct: 204 VEHPSMMS-PLTVQWSARS 221


>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 2/75 (2%)

Query: 39  LVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVC VSGFYP  + V W R G++E+ G     ++ N D T+     L+         +C+
Sbjct: 131 LVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQ 190

Query: 98  VKHSSLGGHDLIIHW 112
           V+H S+    L + W
Sbjct: 191 VEHPSVMS-PLTVEW 204


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 39  LVCHVSGFYPKPVWVMWMR-GEQEQRGTQRGDVLPNADETWYLRATLDVAAGEAAGLSCR 97
           LVC V+GFYP  + V W R G++E+ G     ++ N D T+     L+         +C+
Sbjct: 156 LVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRSGEVYTCQ 215

Query: 98  VKHSSLGGHDLIIHWGGYS 116
           V+H S+    L + W   S
Sbjct: 216 VEHPSMMS-PLTVQWSARS 233


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.465 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,335,025
Number of Sequences: 37866
Number of extensions: 410031
Number of successful extensions: 1735
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1577
Number of HSP's gapped (non-prelim): 139
length of query: 187
length of database: 18,247,518
effective HSP length: 96
effective length of query: 91
effective length of database: 14,612,382
effective search space: 1329726762
effective search space used: 1329726762
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.