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Search of human proteins with 162809334
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|162809334 pregnancy-zone protein [Homo sapiens]
(1482 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|162809334 pregnancy-zone protein [Homo sapiens] 2931 0.0
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens] 2115 0.0
gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens] 984 0.0
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens] 938 0.0
gi|169204289 PREDICTED: ovostatin [Homo sapiens] 890 0.0
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens] 500 e-141
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens] 485 e-136
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens] 449 e-126
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens] 445 e-124
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 308 2e-83
gi|67190748 complement component 4A preproprotein [Homo sapiens] 237 5e-62
gi|178557739 complement component 4B preproprotein [Homo sapiens] 237 5e-62
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s... 236 1e-61
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s... 228 3e-59
gi|115298678 complement component 3 precursor [Homo sapiens] 202 2e-51
gi|38016947 complement component 5 preproprotein [Homo sapiens] 186 1e-46
gi|169218213 PREDICTED: similar to complement component C3, part... 169 2e-41
gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 160 8e-39
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 145 3e-34
gi|239755748 PREDICTED: ovostatin [Homo sapiens] 141 5e-33
gi|239758130 PREDICTED: similar to complement component 4B (Chil... 124 9e-28
gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 114 7e-25
gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 106 1e-22
gi|169217831 PREDICTED: similar to Ovostatin homolog 2 [Homo sap... 79 3e-14
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap... 78 6e-14
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens] 77 9e-14
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg... 74 8e-13
gi|239755754 PREDICTED: ovostatin 2 [Homo sapiens] 57 1e-07
gi|169214179 PREDICTED: similar to complement component 3 [Homo ... 45 7e-04
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens] 35 0.54
>gi|162809334 pregnancy-zone protein [Homo sapiens]
Length = 1482
Score = 2931 bits (7599), Expect = 0.0
Identities = 1482/1482 (100%), Positives = 1482/1482 (100%)
Query: 1 MRKDRLLHLCLVLLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVS 60
MRKDRLLHLCLVLLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVS
Sbjct: 1 MRKDRLLHLCLVLLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVS 60
Query: 61 ASLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQDFRKRNTVL 120
ASLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQDFRKRNTVL
Sbjct: 61 ASLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQDFRKRNTVL 120
Query: 121 VLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSL 180
VLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSL
Sbjct: 121 VLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSL 180
Query: 181 KLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISI 240
KLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISI
Sbjct: 181 KLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISI 240
Query: 241 MDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNGCITQQV 300
MDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNGCITQQV
Sbjct: 241 MDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNGCITQQV 300
Query: 301 HTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFRQGIP 360
HTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFRQGIP
Sbjct: 301 HTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFRQGIP 360
Query: 361 FFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVF 420
FFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVF
Sbjct: 361 FFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVF 420
Query: 421 TVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNR 480
TVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNR
Sbjct: 421 TVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNR 480
Query: 481 QAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFA 540
QAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFA
Sbjct: 481 QAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFA 540
Query: 541 ILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSV 600
ILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSV
Sbjct: 541 ILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSV 600
Query: 601 LLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLSSNEA 660
LLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLSSNEA
Sbjct: 601 LLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLSSNEA 660
Query: 661 DIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYN 720
DIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYN
Sbjct: 661 DIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYN 720
Query: 721 VIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSE 780
VIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSE
Sbjct: 721 VIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSE 780
Query: 781 DAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAF 840
DAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAF
Sbjct: 781 DAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAF 840
Query: 841 LASQNTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIK 900
LASQNTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIK
Sbjct: 841 LASQNTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIK 900
Query: 901 RKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDI 960
RKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDI
Sbjct: 901 RKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDI 960
Query: 961 LGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQR 1020
LGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQR
Sbjct: 961 LGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQR 1020
Query: 1021 QLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQ 1080
QLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQ
Sbjct: 1021 QLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQ 1080
Query: 1081 KDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNV 1140
KDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNV
Sbjct: 1081 KDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNV 1140
Query: 1141 AKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVG 1200
AKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVG
Sbjct: 1141 AKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVG 1200
Query: 1201 HLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDT 1260
HLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDT
Sbjct: 1201 HLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDT 1260
Query: 1261 VVALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVI 1320
VVALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVI
Sbjct: 1261 VVALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVI 1320
Query: 1321 TVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRP 1380
TVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRP
Sbjct: 1321 TVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRP 1380
Query: 1381 ASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVL 1440
ASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVL
Sbjct: 1381 ASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVL 1440
Query: 1441 QDIPVGDLKPAIVKVYDYYETDESVVAEYIAPCSTDTEHGNV 1482
QDIPVGDLKPAIVKVYDYYETDESVVAEYIAPCSTDTEHGNV
Sbjct: 1441 QDIPVGDLKPAIVKVYDYYETDESVVAEYIAPCSTDTEHGNV 1482
>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
Length = 1474
Score = 2115 bits (5480), Expect = 0.0
Identities = 1072/1481 (72%), Positives = 1236/1481 (83%), Gaps = 16/1481 (1%)
Query: 1 MRKDRLLHLCLVLLLILLSASDSN-STEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTV 59
M K++LLH LVLLL++L +D++ S +PQYMVLVPSLLHTE +KGCVLLS+LNETVTV
Sbjct: 1 MGKNKLLHPSLVLLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTV 60
Query: 60 SASLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQDFRKRNTV 119
SASLES R NRSLFTDL AE D+ HCV+F +P+ S++ EV FL++Q+KGPTQ+F+KR TV
Sbjct: 61 SASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTV 120
Query: 120 LVLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQS 179
+V N SLVFVQTDK +YKPGQTV+FRVVS+DENF P NELIPL+Y+++P+ NRIAQWQS
Sbjct: 121 MVKNEDSLVFVQTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQS 180
Query: 180 LKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIIS 239
+LE G+ Q SFPLSSEP QGSY+VVVQ +SGGR +HPFTVEEFVLPKFEV+V VPKII+
Sbjct: 181 FQLEGGLKQFSFPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIIT 240
Query: 240 IMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNC---DKQEVCEEFSQQLNSNGCI 296
I++E++N++VCG YTYGKPVPG TVS+CRK S +C D Q CE+FS QLNS+GC
Sbjct: 241 ILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCHGEDSQAFCEKFSGQLNSHGCF 300
Query: 297 TQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFR 356
QQV TK+ Q+ +EMKL EA+I+EEGT +E+T + SEIT ++KL FVKVDSHFR
Sbjct: 301 YQQVKTKVFQLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFR 360
Query: 357 QGIPFFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLF 416
QGIPFF QV LVDGKGVPIPNK+ FI N+ANYYSNATT+E GL QFSINTT++ L
Sbjct: 361 QGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLT 420
Query: 417 VRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHY 476
VRV + C+ Y WV+E+H+ A HTA VFS S S++HLEP++ LPCGHT+T+ AHY
Sbjct: 421 VRVNYKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHY 480
Query: 477 TLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARM 536
LN + L +LSF+YLIMAKG IVR+GTH L V+ DMKG F++S PV+SD+AP+AR+
Sbjct: 481 ILNGGTLLGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARL 540
Query: 537 FIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAV 596
I+A+LP G+V+GDS K+++ENCLANKVDLSFSP+QS PASHAHL+V AAPQS+CALRAV
Sbjct: 541 LIYAVLPTGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAV 600
Query: 597 DQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLS 656
DQSVLLMKP+AELS SSVYNLL KDLT FP ++ Q++E +I NG Y P+S
Sbjct: 601 DQSVLLMKPDAELSASSVYNLLPEKDLTGFPGPLNDQDDEDCINRHNVYI-NGITYTPVS 659
Query: 657 S-NEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQ 715
S NE D+YSFL+ MGLK FTNSKIRKPK C + G G +G E + +
Sbjct: 660 STNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEM----HGPEGLRVGFYESDVMGR 715
Query: 716 LGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGA 775
G ++ + P ETVR YFPETWIW+LV VNS+GVAEVGVTVPDTITEWKAGA
Sbjct: 716 -GHARLVHVEE-----PHTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGA 769
Query: 776 FCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLK 835
FCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGE FTLKATVLNYLPKCIRVSVQL+
Sbjct: 770 FCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLE 829
Query: 836 ASPAFLASQNTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVE 895
ASPAFLA K + +CIC N RQT+SW VTPK+LGNVNF+VSAEA++S ELCG EV
Sbjct: 830 ASPAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPS 889
Query: 896 VPEIKRKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFS 955
VPE RKDTVIK LLVE EG+E+E TF+S+ C SG VSE+LSLKLP NVV+ESARAS S
Sbjct: 890 VPEHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVS 949
Query: 956 VLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLI 1015
VLGDILGSAMQN QNLLQMPYGCGEQNMVLFAPNIYVL+YLNETQQLT EIK+KA+GYL
Sbjct: 950 VLGDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLN 1009
Query: 1016 TGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTW 1075
TGYQRQLNYKH DGSYSTFGERYGRNQGNTWLTAFVLKTFAQAR+YIFIDEAHITQ+L W
Sbjct: 1010 TGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIW 1069
Query: 1076 LSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLE 1135
LSQ QKDNGCFRSSGSLLNNAIKGGVEDE TLSAY+TIALLEIPL VT+P+VRNALFCLE
Sbjct: 1070 LSQRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLE 1129
Query: 1136 SAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRP 1195
SAW A+EG HGSHVYTKALLAYAF+L G Q++ +E+L SL++EAVK+DN VHWERPQ+P
Sbjct: 1130 SAWKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKP 1189
Query: 1196 KAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFS 1255
KAPVGH Y+ QAPSAEVEMTSYVLLAYLTAQPAPTS DLTSATNIVKWI KQQNAQGGFS
Sbjct: 1190 KAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFS 1249
Query: 1256 STQDTVVALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELP 1315
STQDTVVALHALS+YGAATFTRT K AQVT+Q S TFS+ FQVDNNN LLLQQ+SLPELP
Sbjct: 1250 STQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELP 1309
Query: 1316 GEYVITVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISY 1375
GEY + VTGE CVYLQTS+KYNILPEKE+ PFAL VQT+PQTCD KAHTSFQISL++SY
Sbjct: 1310 GEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSY 1369
Query: 1376 TGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSF 1435
TG+R ASNM IVDVKMVSGFIPLKPTVKMLERS+ VSRTEVS+NHVLIY+++V+NQTLS
Sbjct: 1370 TGSRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSL 1429
Query: 1436 SFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAPCSTD 1476
F VLQD+PV DLKPAIVKVYDYYETDE +AEY APCS D
Sbjct: 1430 FFTVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPCSKD 1470
>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
Length = 1454
Score = 984 bits (2545), Expect = 0.0
Identities = 564/1487 (37%), Positives = 851/1487 (57%), Gaps = 64/1487 (4%)
Query: 13 LLLILLSASDSNSTE-PQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRS 71
LLL +L+ S + + E P Y+V +P+ L+ + +K C+ LS V + +LE+ + +
Sbjct: 5 LLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQK 64
Query: 72 LFTDLVAEKDLFHCVSFTLPR-ISASSEVAFLSIQIKGPTQDFRKRNTVLVLNTQSLVFV 130
L +K HC+SF +P + EVA + + G F ++ VL+ + FV
Sbjct: 65 LLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFV 124
Query: 131 QTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGINQLS 190
QTDKP+Y PGQ V FR+V++D NF P N+ ++ L++P NRIAQW + E GI LS
Sbjct: 125 QTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLS 184
Query: 191 FPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVNITVC 250
F L+ E + G+Y V V + G+ F+VEE+VLPKF+V+V PK +S + E + +C
Sbjct: 185 FQLAPEAMLGTYTVAV---AEGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKIC 241
Query: 251 GEYTYGKPVPGLATVSLCRKLS-----RVLNCDKQEVCEEFSQQLNSNGCITQQVHTKML 305
YTYGKP+ G VS+C+K + V + C S Q + GC + V
Sbjct: 242 CRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATF 301
Query: 306 QITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFRQGIPFFAQV 365
+ + ++ + A + EEGT +E A + I+ + + F + + PF ++
Sbjct: 302 DLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGKI 361
Query: 366 LLVDGKGVPIPNKLFFISVNDANYYSNAT--TNEQGLAQFSINTTSISVNKLFVRVFTVH 423
+ + N L F+ + N N T T+ GLA F++ T+ + + +
Sbjct: 362 RVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQM 421
Query: 424 PNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAM 483
+L ++ V +Q A +S + S++ + + G L CG + + Y ++
Sbjct: 422 EDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADA 481
Query: 484 GELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFAILP 543
E+SF Y ++ KG +V G L + +K SF+LS S +AP + I+AI P
Sbjct: 482 SPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFP 541
Query: 544 DGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLM 603
G VV D +F +E C N+V L FSP+Q P + LQ+ AAP SLCALRAVD+SVLL+
Sbjct: 542 SGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLL 601
Query: 604 KPEAELSVSSVYNLLTVKDLTNFPDNVDQQEE-----------------EQGHCPRPFFI 646
+P+ ELS SVY + ++P V + ++ QGH +
Sbjct: 602 RPDRELSNRSVYGMFPFW-YGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQ---- 656
Query: 647 HNGAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLG 706
I+ P S D++SF + +GLK+ +N+KI+KP CS + A+G AG G
Sbjct: 657 -RSIIWRPSFSEGTDLFSFFRDVGLKILSNAKIKKPVDCSHRSPEYSTAMG-----AGGG 710
Query: 707 VVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPD 766
P + T PL+ + S VR YFPETW+W+L + +SG V VTVPD
Sbjct: 711 ---HPEAFESST----PLHQAEDS-----QVRQYFPETWLWDLFPIGNSGKEAVHVTVPD 758
Query: 767 TITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPK 826
ITEWKA +FC S+ G G+S T L AF+PFFV+LT+PYSV+RGE F L AT+ NYL
Sbjct: 759 AITEWKAMSFCTSQSRGFGLSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKD 818
Query: 827 CIRVSVQLKASPAFLASQNTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSL 886
CIRV L S + + S C+C +E +T W +T LG++NF++S + + S
Sbjct: 819 CIRVQTDLAKSHEYQLESWADSQTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSN 878
Query: 887 ELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVV 946
E CG + VP+ R DT+IK +LV+ EG+ EKT SS+ C G SE +SL+LP ++V
Sbjct: 879 EPCGGQKGFVPQKGRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIV 938
Query: 947 KESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEI 1006
+S +A +VLGDI+G+A+QN+ L+QMP GCGEQNMVLFAP IYVL YL + LT+EI
Sbjct: 939 PDSTKAYVTVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEI 998
Query: 1007 KAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDE 1066
+++AVG+L GYQ++L YKH +GSYS FGER G GNTWLTAFV K F QA+ +IFID
Sbjct: 999 RSRAVGFLEIGYQKELMYKHSNGSYSAFGERDG--NGNTWLTAFVTKCFGQAQKFIFIDP 1056
Query: 1067 AHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPI 1126
+I +L W++ Q +GC+ + G+LL+ A+KGGV+DE +L+AYVT ALLE+ V +P+
Sbjct: 1057 KNIQDALKWMAGNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPM 1116
Query: 1127 VRNALFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNL 1186
V L CL+++ T +++YT+ALLAY FSL G+ + +L LD++A+
Sbjct: 1117 VSQGLRCLKNS------ATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGES 1170
Query: 1187 VHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMK 1246
++W Q+P ++ + +VE+T+Y LLA LT +P+ T ++ AT+IV W+ K
Sbjct: 1171 IYWS--QKPTPSSNASPWSEPAAVDVELTAYALLAQLT-KPSLTQKEIAKATSIVAWLAK 1227
Query: 1247 QQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLL 1306
Q+NA GGFSSTQDTVVAL AL++Y + +E+ + V+ ++ F F + + N L+
Sbjct: 1228 QRNAYGGFSSTQDTVVALQALAKYATTAYMPSEE-INLVVKSTENFQRTFNIQSVNRLVF 1286
Query: 1307 QQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTS 1366
QQ +LP +PG Y + +G+ CVY+QT ++YNILP F+L V+ C+ + S
Sbjct: 1287 QQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRS 1346
Query: 1367 FQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVE 1426
+++ SY G+R +SNM IV+VKM+SGF P++ T ++L + V + E + + IY++
Sbjct: 1347 LTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLD 1406
Query: 1427 QVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAPC 1473
++ T +++F + Q + V +LKPA +KVYDYY DE +Y PC
Sbjct: 1407 ELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDPC 1453
>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
Length = 1394
Score = 938 bits (2424), Expect = 0.0
Identities = 538/1401 (38%), Positives = 827/1401 (59%), Gaps = 57/1401 (4%)
Query: 29 QYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSLFTDLVAEKDLFHCVSF 88
QY++L+PS+L + K C L +L E+V ++ SL G +F + V ++ F C+SF
Sbjct: 12 QYVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENVTGENFFKCISF 71
Query: 89 TLPRISASSEVAFLSIQIKGPTQDFRKRNTVLVLNTQSLVFVQTDKPMYKPGQTVRFRVV 148
+P+ + S +AF++ KG T + +R +V + + +++VFVQTDKP YKPGQ V
Sbjct: 72 EVPQ-ARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQK---DVN 127
Query: 149 SVDENFRPRNELI-PLIYLENPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQ 207
+ + F P I L++P+ NRI QWQ++ I QLSF L SEP+ G Y +VV+
Sbjct: 128 GIAQFFLDTYTFTYPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVK 187
Query: 208 TESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSL 267
S + H F V+ +VLPKFEV V P+ ++I D++ + VC +YT+G+PV G + +
Sbjct: 188 RNSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQGKTQIRV 247
Query: 268 CRKLSRVLNCDKQ--EVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREE 325
CR+ NC+K E+CE+F QL NGC++Q V+TK+ Q+ +G M V + E
Sbjct: 248 CREYFSSSNCEKNDNEICEQFIAQLE-NGCVSQIVNTKVFQLYRSGLFMTFHVAVIVTEF 306
Query: 326 GTD---LEVTANRISEITNIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFI 382
GT ++++ IT ++ + F +D+ +R+GI +F + D VP+ NKL +
Sbjct: 307 GTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQL 366
Query: 383 SVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQH 442
+ND + N TT+E G AQFSI+T+ I + ++ V P C+ SW+ + A
Sbjct: 367 ELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQYLDAHF 425
Query: 443 TANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIV 502
+R +S + S++ + P L C H + +T HY+LN +A + S + F YL+
Sbjct: 426 LVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSH--- 482
Query: 503 RSGTHTLPVESGDM----KGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIEN 558
SG + S + G+F+ + +D+AP A +F++ + P GE+V DS +F+++
Sbjct: 483 DSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDK 542
Query: 559 CLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLL 618
C +KV++ FS Q P S+A L + AAP CAL AVD +VLL+K E +LS SVYN++
Sbjct: 543 CFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMV 602
Query: 619 -TVKDLTNFPDNVDQQEEEQGHC-PRPFFIHNGAIYVPLSS-NEADIYSFLKGMGLKVFT 675
+++ F ++ + ++ C P+ +NG Y P+S+ + DIY+ ++ MGLKVFT
Sbjct: 603 PSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFT 662
Query: 676 NSKIRKPKSCSV---IPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGP 732
N RKP+ C + +P + YG V R + G N +
Sbjct: 663 NLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSR--IACRGE------NADYVEQA 714
Query: 733 VPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 792
+ +TVR+ FPETW+W+LV+V+SSG A + +PDTIT+W+A FC++ D G GISST +L
Sbjct: 715 IIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTL 774
Query: 793 RAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNT-KGEES 851
QPFF+E+ P+SV++ E F L +YL C+ +SVQ++ S + A+ NT K S
Sbjct: 775 EVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKINGS 834
Query: 852 YCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLV 911
I R+T WT+ PK LG VN +V AE+ QS C NE +E ++ KDTV+K+ LV
Sbjct: 835 EVIQAGGRKTNIWTIIPKKLGKVNITVVAESKQS-SACPNEGMEQQKLNWKDTVVKSFLV 893
Query: 912 EAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNL 971
E EGIE+E+T S + C GA S+Q L LP++VV+ SAR F+V+GDILG AMQN+ +
Sbjct: 894 EPEGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLV-V 952
Query: 972 LQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSY 1031
LQMPYG GEQN L A + YVL+YL T+QLT+E+++KA L GYQRQL++K+ DGSY
Sbjct: 953 LQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSY 1012
Query: 1032 STFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGS 1091
S F ++ +G+ WL+A KT + + ++FIDE Q+L WLS QK +GCF++ G
Sbjct: 1013 SVFWQQ--NQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKTSGCFKNDGQ 1070
Query: 1092 LLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTHGSHVY 1151
L N+A +GG E++ +L+AYV E L T P +RNALFCLE+A + T+G Y
Sbjct: 1071 LFNHAWEGGDEEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALDSGV--TNG---Y 1125
Query: 1152 TKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAE 1211
A+LAYAF+L GK+ Q +L +LD+ A K +N+++WER ++PK + APSA+
Sbjct: 1126 NHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWAPSAQ 1185
Query: 1212 VEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYG 1271
E + YVLLA ++ + DLT A+ IV+W+ +Q N+ GGFSS Q V L ++ G
Sbjct: 1186 TEKSCYVLLAVISRK----IPDLTYASKIVQWLAQQMNSHGGFSSNQVINVGLILIAICG 1241
Query: 1272 -AATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVITVTGERCVYL 1330
F++ Q TV S S+ Q + +N LL+Q+ + + PG+Y + V G C ++
Sbjct: 1242 EEGLFSKN----QNTVTFSSEGSSEIQFNGHNRLLVQRSEVTQAPGQYTVDVEGRGCTFI 1297
Query: 1331 QTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVK 1390
Q ++KYN+L K+ S F+L ++ V + + T F +++ + YTG R S+MV++DVK
Sbjct: 1298 QATLKYNVLLPKKASGFSLSLEIVK-----NYSLTVFDLTVNLKYTGIRNKSSMVVIDVK 1352
Query: 1391 MVSGFIPLKPTVKMLERSSSV 1411
M+SGF P +++ + S +
Sbjct: 1353 MLSGFTPTMSSIEEVNNRSLI 1373
>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
Length = 1353
Score = 890 bits (2299), Expect = 0.0
Identities = 513/1338 (38%), Positives = 790/1338 (59%), Gaps = 56/1338 (4%)
Query: 96 SSEVAFLSIQIKGPTQDFRKRNTVLVLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFR 155
S +AF++ KG T + +R +V + + +++VFVQTDKP YKPGQ V + + F
Sbjct: 29 SDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQK---DVNGIAQFFL 85
Query: 156 PRNELI-PLIYLENPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRI 214
P I L++P+ NRI Q Q++ I QLSF L SEP+ G Y +VV+ S +
Sbjct: 86 DTYTFTYPNITLKDPQNNRIFQRQNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSRETV 145
Query: 215 QHPFTVEEFVLPKFEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRV 274
H F V+ +VLPKFEV V P+ ++I D++ + VC +Y +G+PV G + +CR+
Sbjct: 146 THQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYNFGQPVQGETQIRVCREYFSS 205
Query: 275 LNCDKQE--VCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREEGTD---L 329
NC+K E +CE+F QL NGC++Q V+TK+ Q+ +G M V + E GT +
Sbjct: 206 SNCEKNENEICEQFIAQLE-NGCVSQIVNTKVFQLYRSGLFMTFHVAVIVTESGTGNYFM 264
Query: 330 EVTANRISEITNIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFISVNDANY 389
+++ IT ++ + F +D+ +R+GI +F + D VP+ NKL + +ND +
Sbjct: 265 QISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLLQLELND-EF 323
Query: 390 YSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFS 449
N TT+E G AQFSI+T+ I + ++ V P C+ SW+ + A +R +S
Sbjct: 324 IGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFLVSRFYS 383
Query: 450 LSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTL 509
+ S++ + P L C + +T HY+LN +A + S + F YL+ SG
Sbjct: 384 RTNSFLKIVPEPKQLECNQQKVVTVHYSLNSEAYEDDSNVKFFYLVSLSH---DSGNFQH 440
Query: 510 PVESGDM----KGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVD 565
+ S + G+F+ + +D+AP A +F++ + P GE+V DS +F+++ C +KV+
Sbjct: 441 RISSSPIYTAWNGNFSFPISISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVN 500
Query: 566 LSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLL-TVKDLT 624
+ FS Q P S+A L + AAP CALRAVD++VLL+K E +LS SVYN++ +++
Sbjct: 501 IKFSNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESVYNMVPSIEPYG 560
Query: 625 NFPDNVDQQEEEQGHC-PRPFFIHNGAIYVPLSS-NEADIYSFLKGMGLKVFTNSKIRKP 682
F ++ + ++ C P+ +NG Y P+S+ + DIY+ ++ MGLKVFTN RKP
Sbjct: 561 YFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKVFTNLHYRKP 620
Query: 683 KSCSV---IPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGPVPETVRS 739
+ C + +P + YG V R + G N + + +TVR+
Sbjct: 621 EVCVMERRLPLPKPLYLETENYGPMRSVPSR--IACRGE------NADYVEQAIIQTVRT 672
Query: 740 YFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPFF 799
FPETW+W+LV+V+SSG A + +PDTIT+W+A FC++ D G GISST +L QPFF
Sbjct: 673 NFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFF 732
Query: 800 VELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNT-KGEESYCICGNE 858
+E+ P+SV++ E F L V +Y C+ +SVQ++ S + A+ +T K S I
Sbjct: 733 IEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANIHTLKINGSEVIQAGG 792
Query: 859 RQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQ 918
R+T WT+ PK LG VN +V AE+ QS C NE +E ++ KDTV+++ LVE EGIE+
Sbjct: 793 RKTNVWTIIPKKLGKVNITVVAESKQS-SACPNEGMEQQKLNWKDTVVQSFLVEPEGIEK 851
Query: 919 EKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGC 978
E+T S + C GA S+Q L LP++VV+ SAR F+V+GDILG A+QN+ +LQMPYG
Sbjct: 852 ERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLALQNLV-VLQMPYGS 910
Query: 979 GEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERY 1038
GEQN L A + YVL+YL T+QLT+E+++KA L GYQRQL++K+ DGSYS F ++
Sbjct: 911 GEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQRQLSFKNSDGSYSVFWQQ- 969
Query: 1039 GRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIK 1098
+G+ L+A KT + + Y+FIDE Q+L WLS QK +GCF++ G L N+A +
Sbjct: 970 -SQKGSIXLSALTFKTLERMKKYVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHAWE 1028
Query: 1099 GGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTHGSHVYTKALLAY 1158
GG E++ +L+AYV E L T P +RNALFCLE+A + T+G Y A+LAY
Sbjct: 1029 GGDEEDISLTAYVVGMFFEAGLNFTFPALRNALFCLEAALDSGV--TNG---YNHAILAY 1083
Query: 1159 AFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYV 1218
AF+L GK+ Q +L +LD+ A K +N+++WER ++PK + APSA+ E + YV
Sbjct: 1084 AFALAGKEKQVESLLQTLDQSAPKLNNVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYV 1143
Query: 1219 LLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRT 1278
LLA ++ + DLT A+ IV+W+ ++ N+ GGFSS Q V L ++ R
Sbjct: 1144 LLAVISRK----IPDLTYASKIVQWLAQRMNSHGGFSSNQVINVGLILIAICLMQKLARG 1199
Query: 1279 EKTAQVTVQDSQTFSTN-----FQVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTS 1333
E+ Q++ TFS+ FQV+ +N LL+Q+ + + PGEY + V G C ++Q +
Sbjct: 1200 EEGLFSKDQNTVTFSSEGSSEIFQVNGHNRLLVQRSEVTQAPGEYTVDVEGHGCTFIQAT 1259
Query: 1334 MKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVS 1393
+KYN+L K+ S F+L ++ V + + T+F +++T+ YTG R S+MV++DVKM+S
Sbjct: 1260 LKYNVLLPKKASGFSLSLEIVK-----NYSSTAFDLTVTLKYTGIRNKSSMVVIDVKMLS 1314
Query: 1394 GFIPLKPTVKMLERSSSV 1411
GF P +++ + S +
Sbjct: 1315 GFTPTMSSIEEVNNRSLI 1332
>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
Length = 1445
Score = 500 bits (1287), Expect = e-141
Identities = 426/1504 (28%), Positives = 701/1504 (46%), Gaps = 168/1504 (11%)
Query: 14 LLILLSASDSNSTEPQYMVLVPSLLHTEAPKK-GCVLLSHLNETVTVSASLESGRENRS- 71
LL + +A+ + + P+++V P ++ G LL H VTV A L N +
Sbjct: 12 LLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTV 71
Query: 72 --LFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQD--FRKRNTVLVLNTQSL 127
L + V EK F + TLP + +S +++ G TQD +T L T+ +
Sbjct: 72 SVLEAEGVFEKGSFK--TLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRI 129
Query: 128 -VFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGI 186
VF+QTDK +YKP Q V+FR+V++ +F+P + ++ +++P+ N I QW S + + G+
Sbjct: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGV 188
Query: 187 NQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVN 246
+F LSS PI G + + VQ Q F V E+VLPKFEV +Q P S+ + +N
Sbjct: 189 ISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPKFEVTLQTPLYCSMNSKHLN 247
Query: 247 ITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNGCITQQVHTKMLQ 306
T+ +YTYGKPV G T++ L K+ + + F ++N + ++
Sbjct: 248 GTITAKYTYGKPVKGDVTLTF---LPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMD 304
Query: 307 ITNTGFE-MKLRVEARIREEGTDLE-VTANRISEITNIVSK-----LKFVKVDSHFRQGI 359
+N E + L + T E VT + TN+ K ++F + + +
Sbjct: 305 SSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSL 364
Query: 360 PFFAQVLLV--DGKGVPIPNKLFFISV-----NDANYYSNATTNEQGL-AQFSINTT--S 409
F A V + DG + + + + + N Y+S + + Q + A IN T
Sbjct: 365 NFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQ 424
Query: 410 ISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHT 469
K+ + L ++ A H+ + S S +YI L+ + G
Sbjct: 425 SGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SPSKTYIQLKTRDENIKVG-- 480
Query: 470 ETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESD 529
+ + L L ELS Y+++++G +V G + S S E+
Sbjct: 481 ----SPFELVVSGNKRLKELS--YMVVSRGQLVAVGK----------QNSTMFSLTPENS 524
Query: 530 VAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAA-PQ 588
P A + ++ I DGE++ D K ++ NK+ L +S ++ P+ L+++ P
Sbjct: 525 WTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPD 584
Query: 589 SLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHN 648
S+ + AVD+SV LM ++++ +V + L ++N
Sbjct: 585 SIVGIVAVDKSVNLMNASNDITMENVVHELE--------------------------LYN 618
Query: 649 GAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVV 708
Y+ + N ++ + GL V T++ + K G Y
Sbjct: 619 TGYYLGMFMNS---FAVFQECGLWVLTDANLTK--------DYIDGVYDNAEYAERFMEE 667
Query: 709 ERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTI 768
++ + +++ G P VR +FPETWIW + E VTVPD+I
Sbjct: 668 NEGHIVDIHDFSL---------GSSPH-VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSI 717
Query: 769 TEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKC 827
T W A F +SED GLG+++T L+AFQPFF+ L +PYSVIRGE F L+ T+ NYL
Sbjct: 718 TSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDA 777
Query: 828 IRVSVQLKASPAF--LASQN----TKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAE 881
V V ++ S F L + N T +++ + + T+ + + P LG + +V+A
Sbjct: 778 TEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTAL 837
Query: 882 AMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTFS---SMTCASGANVSEQLS 938
+ + D V + +LV+AEGIE+ + S +T + + LS
Sbjct: 838 SPTA----------------SDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLS 881
Query: 939 LKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNE 998
P N V S R + +GD+LG ++ + +L++MPYGCGEQNM+ FAPNIY+L+YL +
Sbjct: 882 FSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTK 941
Query: 999 TQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQA 1058
+QLT +K KA+ ++ GYQR+L Y+ +DGS+S FG G+TWL+AFVL+ F +A
Sbjct: 942 KKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY--DPSGSTWLSAFVLRCFLEA 999
Query: 1059 RSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEI 1118
YI ID+ + ++ TWL QK NG F G ++++ ++GG + TL+AY+ +LL
Sbjct: 1000 DPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGY 1059
Query: 1119 PLPVTNPIVRNALFCLESAWNVAKEGTHG-SHVYTKALLAYAFSLLGKQNQNREILNSLD 1177
N V+ ++ LES E + G S YT AL+ YA S +G + +E LN L
Sbjct: 1060 RKYQPNIDVQESIHFLES------EFSRGISDNYTLALITYALSSVGSP-KAKEALNMLT 1112
Query: 1178 KEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSA 1237
A +E + W + + Q S ++E+ +Y LL++ +
Sbjct: 1113 WRAEQEGGMQFWVSSESKLSD-----SWQPRSLDIEVAAYALLSHF------LQFQTSEG 1161
Query: 1238 TNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKT-AQVTVQ-DSQTFSTN 1295
I++W+ +Q+N+ GGF+STQDT VAL ALS + A TE+T QVTV S
Sbjct: 1162 IPIMRWLSRQRNSLGGFASTQDTTVALKALSEF--AALMNTERTNIQVTVTGPSSPSPVK 1219
Query: 1296 FQVDNNNLLLLQQISLPEL-PGEYVITVTGERCVYLQTSMKYNILPE---------KEDS 1345
F +D +N LLLQ L + P I+ G Q ++ YN+ +
Sbjct: 1220 FLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQE 1279
Query: 1346 PFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKML 1405
F L V D + H + + S G S M +++V ++SGF+ + +
Sbjct: 1280 AFDLDVAVKENKDDLN--HVDLNVCTSFSGPGR---SGMALMEVNLLSGFMVPSEAISL- 1333
Query: 1406 ERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESV 1465
S +V + E + + +Y++ V + +++ V + + A V + DYYE
Sbjct: 1334 --SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQA 1391
Query: 1466 VAEY 1469
V Y
Sbjct: 1392 VRSY 1395
>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
Length = 1428
Score = 485 bits (1248), Expect = e-136
Identities = 420/1502 (27%), Positives = 695/1502 (46%), Gaps = 181/1502 (12%)
Query: 14 LLILLSASDSNSTEPQYMVLVPSLLHTEAPKK-GCVLLSHLNETVTVSASLESGRENRS- 71
LL + +A+ + + P+++V P ++ G LL H VTV A L N +
Sbjct: 12 LLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTV 71
Query: 72 --LFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIKGPTQD--FRKRNTVLVLNTQSL 127
L + V EK F + TLP + +S +++ G TQD +T L T+ +
Sbjct: 72 SVLEAEGVFEKGSFK--TLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRI 129
Query: 128 -VFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGI 186
VF+QTDK +YKP Q V+FR+V++ +F+P + ++ +++P+ N I QW S + + G+
Sbjct: 130 SVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGV 188
Query: 187 NQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVN 246
+F LSS PI G + + VQ Q F V E+VLPKFEV +Q P S+ + +N
Sbjct: 189 ISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPKFEVTLQTPLYCSMNSKHLN 247
Query: 247 ITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNGCITQQVHTKMLQ 306
T+ +YTYGKPV G T++ L K+ + + F ++N + ++
Sbjct: 248 GTITAKYTYGKPVKGDVTLTF---LPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMD 304
Query: 307 ITNTGFE-MKLRVEARIREEGTDLE-VTANRISEITNIVSK-----LKFVKVDSHFRQGI 359
+N E + L + T E VT + TN+ K ++F + + +
Sbjct: 305 SSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSL 364
Query: 360 PFFAQVLLV--DGKGVPIPNKLFFISV-----NDANYYSNATTNEQGL-AQFSINTT--S 409
F A V + DG + + + + + N Y+S + + Q + A IN T
Sbjct: 365 NFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQ 424
Query: 410 ISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHT 469
K+ + L ++ A H+ + S S +YI L+ + G
Sbjct: 425 SGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SPSKTYIQLKTRDENIKVG-- 480
Query: 470 ETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESD 529
+ + L L ELS Y+++++G +V G + S S E+
Sbjct: 481 ----SPFELVVSGNKRLKELS--YMVVSRGQLVAVGK----------QNSTMFSLTPENS 524
Query: 530 VAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAA-PQ 588
P A + ++ I DGE++ D K ++ NK+ L +S ++ P+ L+++ P
Sbjct: 525 WTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPD 584
Query: 589 SLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDNVDQQEEEQGHCPRPFFIHN 648
S+ + AVD+SV LM ++++ +V + L ++N
Sbjct: 585 SIVGIVAVDKSVNLMNASNDITMENVVHELE--------------------------LYN 618
Query: 649 GAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVV 708
Y+ + N ++ + GL V T++ + K G Y
Sbjct: 619 TGYYLGMFMNS---FAVFQECGLWVLTDANLTK--------DYIDGVYDNAEYAERFMEE 667
Query: 709 ERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTI 768
++ + +++ G P VR +FPETWIW + E VTVPD+I
Sbjct: 668 NEGHIVDIHDFSL---------GSSPH-VRKHFPETWIWLDTNMGYRIYQEFEVTVPDSI 717
Query: 769 TEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKC 827
T W A F +SED GLG+++T L+AFQPFF+ L +PYSVIRGE F L+ T+ NYL
Sbjct: 718 TSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDA 777
Query: 828 IRVSVQLKASPAF--LASQN----TKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAE 881
V V ++ S F L + N T +++ + + T+ + + P LG + +V+A
Sbjct: 778 TEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTAL 837
Query: 882 AMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTFS---SMTCASGANVSEQLS 938
+ + D V + +LV+AEGIE+ + S +T + + LS
Sbjct: 838 SPTA----------------SDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLS 881
Query: 939 LKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNE 998
P N V S R + +GD+LG ++ + +L++MPYGCGEQNM+ FAPNIY+L+YL +
Sbjct: 882 FSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTK 941
Query: 999 TQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQA 1058
+QLT +K KA+ ++ GYQR+L Y+ +DGS+S FG G+TWL+AFVL+ F +A
Sbjct: 942 KKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY--DPSGSTWLSAFVLRCFLEA 999
Query: 1059 RSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEI 1118
YI ID+ + ++ TWL QK NG F G ++++ ++GG + TL+AY+ +LL
Sbjct: 1000 DPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGY 1059
Query: 1119 PLPVTNPIVRNALFCLESAWNVAKEGTHG-SHVYTKALLAYAFSLLGKQNQNREILNSLD 1177
N V+ ++ LES E + G S YT AL+ YA S +G + +E LN L
Sbjct: 1060 RKYQPNIDVQESIHFLES------EFSRGISDNYTLALITYALSSVGSP-KAKEALNMLT 1112
Query: 1178 KEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSA 1237
A +E + W + + Q S ++E+ +Y LL++ +
Sbjct: 1113 WRAEQEGGMQFWVSSESKLSD-----SWQPRSLDIEVAAYALLSHF------LQFQTSEG 1161
Query: 1238 TNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKT-AQVTVQDSQTFSTNF 1296
I++W+ +Q+N+ GGF+STQDT VAL ALS + A TE+T QVTV + S
Sbjct: 1162 IPIMRWLSRQRNSLGGFASTQDTTVALKALSEF--AALMNTERTNIQVTVTGPSSPSP-- 1217
Query: 1297 QVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPE---------KEDSPF 1347
L ++Q P I+ G Q ++ YN+ + F
Sbjct: 1218 ------LAVVQ-------PTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAF 1264
Query: 1348 ALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLER 1407
L V D + H + + S G S M +++V ++SGF+ + +
Sbjct: 1265 DLDVAVKENKDDLN--HVDLNVCTSFSGPGR---SGMALMEVNLLSGFMVPSEAISL--- 1316
Query: 1408 SSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVA 1467
S +V + E + + +Y++ V + +++ V + + A V + DYYE V
Sbjct: 1317 SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVR 1376
Query: 1468 EY 1469
Y
Sbjct: 1377 SY 1378
>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
Length = 750
Score = 449 bits (1155), Expect = e-126
Identities = 253/641 (39%), Positives = 383/641 (59%), Gaps = 16/641 (2%)
Query: 377 NKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAED 436
NKL + +ND + N TT+E G AQFSI+T+ I + ++ V P C+ SW+
Sbjct: 3 NKLLQLELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQ 61
Query: 437 HQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIM 496
+ A +R +S + S++ + P L C H + +T HY+LN +A + S + F YL
Sbjct: 62 YLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLCT 121
Query: 497 AKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEI 556
+ + + P+ + G+F+ + +D+AP A +F++ + P GE+V DS +F++
Sbjct: 122 SDSGNFQHRISSSPIYTA-WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 180
Query: 557 ENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYN 616
+ C +KV++ FS Q P S+A L + AAP CAL AVD +VLL+K E +LS SVYN
Sbjct: 181 DKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYN 240
Query: 617 LL-TVKDLTNFPDNVDQQEEEQGHC-PRPFFIHNGAIYVPLSS-NEADIYSFLKGMGLKV 673
++ +++ F ++ + ++ C P+ +NG Y P+S+ + DIY+ ++ MGLKV
Sbjct: 241 MVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRNMGLKV 300
Query: 674 FTNSKIRKPKSCSV---IPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSS 730
FTN RKP+ C + +P + YG V R + + + N +
Sbjct: 301 FTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSR-----IASSGIRGENADYVE 355
Query: 731 GPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTA 790
+ +TVR+ FPETW+W+LV+V+SSG A + +PDTIT+W+A FC++ D G GISST
Sbjct: 356 QAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTT 415
Query: 791 SLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNT-KGE 849
+L QPFF+E+ P+SV++ E F L +YL C+ +SVQ++ S + A+ NT K
Sbjct: 416 TLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTWKIN 475
Query: 850 ESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTL 909
S I R+T WT+ PK LG VN +V AE+ QS C NE +E ++ KDTV+K+
Sbjct: 476 GSEVIQAGGRKTNIWTIIPKKLGKVNITVVAESKQS-SACPNEGMEQQKLNWKDTVVKSF 534
Query: 910 LVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQ 969
LVE EGIE+E+T S + C GA S+Q L LP++VV+ SAR F+V+GDILG AMQN+
Sbjct: 535 LVEPEGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQNLV 594
Query: 970 NLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKA 1010
+LQMPYG GEQN L A + YVL+YL T+QLT+E+++KA
Sbjct: 595 -VLQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKA 634
>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
Length = 1368
Score = 445 bits (1145), Expect = e-124
Identities = 378/1343 (28%), Positives = 619/1343 (46%), Gaps = 158/1343 (11%)
Query: 168 NPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPK 227
+P+ N I QW S + + G+ +F LSS PI G + + VQ Q F V E+VLPK
Sbjct: 93 DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQS-FQVSEYVLPK 151
Query: 228 FEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFS 287
FEV +Q P S+ + +N T+ +YTYGKPV G T++ L K+ + + F
Sbjct: 152 FEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTF---LPLSFWGKKKNITKTFK 208
Query: 288 QQLNSNGCITQQVHTKMLQITNTGFE-MKLRVEARIREEGTDLE-VTANRISEITNIVSK 345
++N + ++ +N E + L + T E VT + TN+ K
Sbjct: 209 INGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFK 268
Query: 346 -----LKFVKVDSHFRQGIPFFAQVLLV--DGKGVPIPNKLFFISV-----NDANYYSNA 393
++F + + + F A V + DG + + + + + N Y+S +
Sbjct: 269 QHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGS 328
Query: 394 TTNEQGL-AQFSINTT--SISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSL 450
+ Q + A IN T K+ + L ++ A H+ + S
Sbjct: 329 NSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFK--SP 386
Query: 451 SGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLP 510
S +YI L+ + G + + L L ELS Y+++++G +V G
Sbjct: 387 SKTYIQLKTRDENIKVG------SPFELVVSGNKRLKELS--YMVVSRGQLVAVGK---- 434
Query: 511 VESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSP 570
+ S S E+ P A + ++ I DGE++ D K ++ NK+ L +S
Sbjct: 435 ------QNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSK 488
Query: 571 AQSPPASHAHLQVAAA-PQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLTNFPDN 629
++ P+ L+++ P S+ + AVD+SV LM ++++ +V + L
Sbjct: 489 VKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELE---------- 538
Query: 630 VDQQEEEQGHCPRPFFIHNGAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIP 689
++N Y+ + N ++ + GL V T++ + K
Sbjct: 539 ----------------LYNTGYYLGMFMNS---FAVFQECGLWVLTDANLTK-------- 571
Query: 690 SVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWEL 749
G Y ++ + +++ G P VR +FPETWIW
Sbjct: 572 DYIDGVYDNAEYAERFMEENEGHIVDIHDFSL---------GSSPH-VRKHFPETWIWLD 621
Query: 750 VAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISST-ASLRAFQPFFVELTMPYSV 808
+ E VTVPD+IT W A F +SED GLG+++T L+AFQPFF+ L +PYSV
Sbjct: 622 TNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSV 681
Query: 809 IRGEVFTLKATVLNYLPKCIRVSVQLKASPAF--LASQN----TKGEESYCICGNERQTL 862
IRGE F L+ T+ NYL V V ++ S F L + N T +++ + + T+
Sbjct: 682 IRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATV 741
Query: 863 SWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTF 922
+ + P LG + +V+A + + D V + +LV+AEGIE+ +
Sbjct: 742 LFPIRPTHLGEIPITVTALSPTA----------------SDAVTQMILVKAEGIEKSYSQ 785
Query: 923 S---SMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCG 979
S +T + + LS P N V S R + +GD+LG ++ + +L++MPYGCG
Sbjct: 786 SILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCG 845
Query: 980 EQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYG 1039
EQNM+ FAPNIY+L+YL + +QLT +K KA+ ++ GYQR+L Y+ +DGS+S FG
Sbjct: 846 EQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNY-- 903
Query: 1040 RNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKG 1099
G+TWL+AFVL+ F +A YI ID+ + ++ TWL QK NG F G ++++ ++G
Sbjct: 904 DPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQG 963
Query: 1100 GVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTHG-SHVYTKALLAY 1158
G + TL+AY+ +LL N V+ ++ LES E + G S YT AL+ Y
Sbjct: 964 GNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLES------EFSRGISDNYTLALITY 1017
Query: 1159 AFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYV 1218
A S +G + +E LN L A +E + W + + Q S ++E+ +Y
Sbjct: 1018 ALSSVGSP-KAKEALNMLTWRAEQEGGMQFWVSSESKLSD-----SWQPRSLDIEVAAYA 1071
Query: 1219 LLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRT 1278
LL++ + I++W+ +Q+N+ GGF+STQDT VAL ALS + A T
Sbjct: 1072 LLSHF------LQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEF--AALMNT 1123
Query: 1279 EKT-AQVTVQ-DSQTFSTNFQVDNNNLLLLQQISLPEL-PGEYVITVTGERCVYLQTSMK 1335
E+T QVTV S F +D +N LLLQ L + P I+ G Q ++
Sbjct: 1124 ERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVV 1183
Query: 1336 YNILPE---------KEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVI 1386
YN+ + F L V D + H + + S G S M +
Sbjct: 1184 YNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLN--HVDLNVCTSFSGPGR---SGMAL 1238
Query: 1387 VDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVG 1446
++V ++SGF+ + + S +V + E + + +Y++ V + +++ V
Sbjct: 1239 MEVNLLSGFMVPSEAISL---SETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVS 1295
Query: 1447 DLKPAIVKVYDYYETDESVVAEY 1469
+ + A V + DYYE V Y
Sbjct: 1296 NTQDASVSIVDYYEPRRQAVRSY 1318
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 308 bits (790), Expect = 2e-83
Identities = 192/566 (33%), Positives = 289/566 (51%), Gaps = 54/566 (9%)
Query: 934 SEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVL 993
SE +L +P + S RA+ S++GD++G + ++ NLL++P+GCGEQNM+ FAPN++VL
Sbjct: 1147 SEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNVFVL 1206
Query: 994 NYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLK 1053
YL +TQQL+ E++ + YL+ GYQRQL YK QDGSYS FGER G+ WLTAFVLK
Sbjct: 1207 KYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDA--SGSMWLTAFVLK 1264
Query: 1054 TFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTI 1113
+FAQARS+IF+D + + +W+ Q Q+ +G F + G +LN I+GG+ L+AYV +
Sbjct: 1265 SFAQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVVV 1324
Query: 1114 ALLEIPLPVTNP--IVRNALFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNRE 1171
ALLE A LESA +A + Y+ AL YA +LL + E
Sbjct: 1325 ALLETGTASEEERGSTDKARHFLESAAPLAMD------PYSCALTTYALTLL-RSPAAPE 1377
Query: 1172 ILNSLDKEAVKEDNLVHWERPQRPKAPVGHL------YQTQAPSAEVEMTSYVLLAYLTA 1225
L L A+ D + HW G SAEVEMT+Y LL Y
Sbjct: 1378 ALRKLRSLAIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTYTLL 1437
Query: 1226 QPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVT 1285
GD+ +A +VKW+ +Q+NA GGFSSTQDT VAL AL+ Y ++
Sbjct: 1438 ------GDVAAALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGINLTVSL 1491
Query: 1286 VQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKEDS 1345
+ + F++ N +LQ ++P LP ++ G+ C +Q + YN+
Sbjct: 1492 ASTNLDYQETFELHRTNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVTYNVPDPVAKP 1551
Query: 1346 PFALKVQTVPQTCDGH---------------------------KAHTSFQISLTISYTG- 1377
F L V G + H +++ L +
Sbjct: 1552 AFQLLVSLQEPEAQGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQEYKVMLEVCTRWL 1611
Query: 1378 NRPASNMVIVDVKMVSGFIPLKPTVK--MLERSSSVSRTEVSNNHVLIYVEQVTNQTLS- 1434
+ +SNM +++V ++SGF +++ +L++ + R EV+ VL Y +++ ++ L+
Sbjct: 1612 HAGSSNMAVLEVPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCLTC 1671
Query: 1435 FSFMVLQDIPVGDLKPAIVKVYDYYE 1460
F L++ VG V VYDYYE
Sbjct: 1672 VRFRALRECVVGRTSALPVSVYDYYE 1697
Score = 229 bits (584), Expect = 1e-59
Identities = 240/992 (24%), Positives = 419/992 (42%), Gaps = 116/992 (11%)
Query: 6 LLHLCLVLLLILLSASDS-NSTEPQ---YMVLVPSLLHTEAPKKGCVLLSHLNETVTVSA 61
LL L LLL+LLSA D + +PQ Y++ PS+ + V + + VTV A
Sbjct: 52 LLWPLLPLLLLLLSARDGVRAAQPQAPGYLIAAPSVFRAGVEEVISVTIFNSPREVTVQA 111
Query: 62 SLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFLSIQIK-GPTQDFRKRNTVL 120
L + E + +K T R A +V Q + GP F + +V
Sbjct: 112 QLVAQGEPVVQSQGAILDKGTIKLKVPTGLRGQALLKVWGRGWQAEEGPL--FHNQTSVT 169
Query: 121 VLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSL 180
V + VF+QTDKP+Y+P V + +V N RP NE + Y+ +PR +R+ +W+ L
Sbjct: 170 VDGRGASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVNEKLEA-YILDPRGSRMIEWRHL 228
Query: 181 K-LEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIIS 239
K GI +SFPLS +P+ G + + V+ + G F V+++VLPKFE+ + P+ I
Sbjct: 229 KPFCCGITNMSFPLSDQPVLGEWFIFVEMQ-GHAYNKSFEVQKYVLPKFELLIDPPRYIQ 287
Query: 240 IMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQLNSNG---CI 296
+D TV YT+GKPV G +++ + + ++ L S C+
Sbjct: 288 DLDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVLRTTKILGSRDFDICV 347
Query: 297 TQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVK-VDSHF 355
+ + + F ++ + A + +V + + + + +++ K F
Sbjct: 348 RDMIPADVPE----HFRGRVSIWAMVTSVDGSQQVAFDDSTPVQRQLVDIRYSKDTRKQF 403
Query: 356 RQGIPFFAQVLLVDGKGVPIPNKLFFISVN---DANYYSNATTNEQGLAQFSINTTSISV 412
+ G+ + +V L G P I N Y++ +++GL F I + S
Sbjct: 404 KPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQRGLVGFEIPSIPTSA 463
Query: 413 NKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETI 472
+++ + + V + + + +S S Y+ L+P + L G
Sbjct: 464 QHVWLETKV----MALNGKPVGAQYLPSYLSLGSWYSPSQCYLQLQPPSHPLQVGEEAYF 519
Query: 473 TAHYTLNRQAMGELSELSFHYLIMAKGVIVRSG---THTLPVESGDMKGSFALSFPV--- 526
+ T + +Y + A+G IV SG HT + + + AL P+
Sbjct: 520 SVKSTCP-------CNFTLYYEVAARGNIVLSGQQPAHT--TQQRSKRAAPALEKPIRLT 570
Query: 527 -------------ESDV-------------APIARMFIFAILPDGEVVGDSEKFEIENCL 560
E DV P+ R+ +F + +GE V DS +F +E
Sbjct: 571 HLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEGVADSLQFAVETFF 630
Query: 561 ANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTV 620
N+V +++S ++ P L++ AA S + AVD+SV L++ L+ + V+ L
Sbjct: 631 ENQVSVTYSANETQPGEVVDLRIRAARGSCVCVAAVDKSVYLLRSGFRLTPAQVFQELED 690
Query: 621 KDLTNFPDNVDQQEEEQGHCPRPFF---------IHNGAIYVPLSSNEADIYSFLKGMGL 671
D++ D+ E+ PF+ + P + ++F + GL
Sbjct: 691 YDVS---DSFGVSRED-----GPFWWAGLTAQRRRRSSVFPWPWGITKDSGFAFTE-TGL 741
Query: 672 KVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSG 731
V T+ + + + A Q + G+ + V + P+
Sbjct: 742 VVMTDRVSLNHRQDGGLYTDEAVPAFQPHTGSLVAVAPSRHPPR---------------- 785
Query: 732 PVPETVRSYFPETWIWELVAVNS-SGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTA 790
+ R++FPETWIW + ++ SG + V VPD+IT W A LS GLGI+ +
Sbjct: 786 -TEKRKRTFFPETWIWHCLNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGIAEPS 844
Query: 791 SLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGE- 849
L+ F+PFFV+ +P +IRGE + +V NY+ C V ++L P + G+
Sbjct: 845 LLKTFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSV-PKGIQFVGHPGKR 903
Query: 850 ---ESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSLELC----GNEVVEVPEIKRK 902
+ C+ E + + ++ LG N + A A C ++ E R+
Sbjct: 904 HVTKKMCVAPGEAEPIWVVLSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEENHADRR 963
Query: 903 -----DTVIKTLLVEAEGIEQEKTFSSMTCAS 929
D V ++++VEAEG+ + T+S+ C S
Sbjct: 964 VPIGVDHVRRSVMVEAEGVPRAYTYSAFFCPS 995
>gi|67190748 complement component 4A preproprotein [Homo sapiens]
Length = 1744
Score = 237 bits (605), Expect = 5e-62
Identities = 229/835 (27%), Positives = 360/835 (43%), Gaps = 134/835 (16%)
Query: 737 VRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQ 796
VRS+FPE W+W + V+ + + + +PD++T W+ LS+ GL +++ LR F+
Sbjct: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
Query: 797 PFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGEESYCICG 856
F + L +P SV R E L+ + NYL K + VSV + SP E C+ G
Sbjct: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHV--SPV----------EGLCLAG 879
Query: 857 NERQTLSWTVTPKTLGNVNFSV--SAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAE 914
V + V FSV +A A SL++ E P D V K L +E E
Sbjct: 880 GGGLAQQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPV---GDAVSKVLQIEKE 936
Query: 915 G-IEQEKTFSSMTCASGANVSEQLSLKLPSNVVKES-----ARASFSVLGDILGS----A 964
G I +E+ + + ++ N++ + R + S D LGS +
Sbjct: 937 GAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALS 996
Query: 965 MQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQ---LTQEIKAKAVGYLITGYQRQ 1021
+ +LL++P GCGEQ M+ AP + YL++T+Q L E K AV + GY R
Sbjct: 997 PGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRI 1056
Query: 1022 LNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQK 1081
++ DGSY+ + R +TWLTAFVLK + A+ + + ++ WL Q+
Sbjct: 1057 QQFRKADGSYAAWLSR----DSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQ 1112
Query: 1082 DNGCFRSSGSLLNNAIKGGV---EDEATLSAYVTIALL--------EIPLPVTNPIVRNA 1130
+G F+ +L+ +++GG+ ++ L+A+VTIAL E P+ + +
Sbjct: 1113 ADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASI 1172
Query: 1131 LFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREIL-NSLDKEAVKEDNLVHW 1189
A G G+H A+ AYA +L + N+L A + + ++W
Sbjct: 1173 SKANSFLGEKASAGLLGAH--AAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYW 1230
Query: 1190 --------------ERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLT 1235
P+ P P+ QAP+ +E T+Y LL L + D
Sbjct: 1231 GSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHEGKAEMADQA 1285
Query: 1236 SATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVT---------- 1285
SA W+ +Q + QGGF STQDTV+AL ALS Y A+ T E+ VT
Sbjct: 1286 SA-----WLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFK 1340
Query: 1286 -----------------VQDSQTFSTNFQVDNN-----------NLLLLQQISLPELPGE 1317
+Q S N +V N N+L ++ + +L E
Sbjct: 1341 SHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIE 1400
Query: 1318 YVITVTGERCVYLQTS-----MKYNILPEKEDSPFALKVQTVPQTCDGHK---------- 1362
+TV G ++ + +Y+ LP K+D L+ T Q +G +
Sbjct: 1401 --VTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKV 1458
Query: 1363 ---AHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSS--VSRTEVS 1417
+ ++ I G S M I DV ++SGF L+ ++ L S VS E
Sbjct: 1459 VEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETE 1518
Query: 1418 NNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAP 1472
HVL+Y + V F +Q++PVG ++PA +YDYY + Y AP
Sbjct: 1519 GPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
Score = 83.6 bits (205), Expect = 1e-15
Identities = 152/661 (22%), Positives = 263/661 (39%), Gaps = 95/661 (14%)
Query: 27 EPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSL--------FTDLVA 78
+P+ ++ PS++H P V L + V S+ +R+ FT L +
Sbjct: 20 KPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFT-LSS 78
Query: 79 EKDLFHCVSFTLPRISASSEVAFLSIQIKGPT----------QDFRKRNT------VLVL 122
E+D F +S +P A S L ++GP +D R T +L
Sbjct: 79 ERD-FALLSLQVPLKDAKS--CGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFS 135
Query: 123 NTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKL 182
+ + +F+QTD+P+Y PGQ VR+RV ++D+ RP + I + +EN R+ + + + +
Sbjct: 136 SRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTI-TVMVENSHGLRVRK-KEVYM 193
Query: 183 EAGINQLSFPLSSEPIQGSYRVVVQTESG--GRIQHPFTVEEFVLPKFEVKVQ--VPKII 238
+ I Q F + G++++ + G F V+++VLP FEVK+ P I+
Sbjct: 194 PSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYIL 253
Query: 239 SIMD--EKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEV----CEEFSQQLN- 291
++ +++ + + Y YGKPV G+A V +L+ D ++ E ++ +N
Sbjct: 254 TVPGHLDEMQLDIQARYIYGKPVQGVAYVRF-----GLLDEDGKKTFFRGLESQTKLVNG 308
Query: 292 -SNGCITQQVHTKMLQITNTGFE----MKLRVEARIREE-GTDLEVTANRISEITNIVSK 345
S+ +++ L+ N G ++L V A I E G ++E +
Sbjct: 309 QSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFS 368
Query: 346 LKFVKVDSHFRQGIPFFAQVLLVD-----GKGVPIPNKLFFISVNDANYYSNATTNEQGL 400
L K H G PF Q L+ + G+P+ S + N G
Sbjct: 369 LDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGS 428
Query: 401 AQFSIN---TTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHL 457
Q SI +IS +L V + HP + A+ T S ++ +
Sbjct: 429 GQVSIPIIIPQTISELQLSVSAGSPHPAI-------------ARLTVAAPPSGGPGFLSI 475
Query: 458 EPVAGTLPCGHTETITAHYTLNRQAMGELSELS-FHYLIMAKGVIV---RSGTHTLPVES 513
E P + LN +A+G + S ++Y+I+++G IV R TL
Sbjct: 476 E-----RPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLT--- 527
Query: 514 GDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPA-Q 572
++S V+ +AP F D V K++LS A Q
Sbjct: 528 -------SVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQ 580
Query: 573 SPPASHAHLQVAAAPQSLCALRAVDQSVLL--MKPEAELSVSSVYNLLTVKDLTNFPDNV 630
L + +L AL A+D ++ K L++ V+ + DL P
Sbjct: 581 YRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGG 640
Query: 631 D 631
D
Sbjct: 641 D 641
>gi|178557739 complement component 4B preproprotein [Homo sapiens]
Length = 1744
Score = 237 bits (605), Expect = 5e-62
Identities = 227/835 (27%), Positives = 359/835 (42%), Gaps = 134/835 (16%)
Query: 737 VRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQ 796
VRS+FPE W+W + V+ + + + +PD++T W+ LS+ GL +++ LR F+
Sbjct: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
Query: 797 PFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGEESYCICG 856
F + L +P SV R E L+ + NYL K + VSV + SP E C+ G
Sbjct: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHV--SPV----------EGLCLAG 879
Query: 857 NERQTLSWTVTPKTLGNVNFSV--SAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAE 914
V + V FSV +A SL++ E P D V K L +E E
Sbjct: 880 GGGLAQQVLVPAGSARPVAFSVVPTAATAVSLKVVARGSFEFPV---GDAVSKVLQIEKE 936
Query: 915 G-IEQEKTFSSMTCASGANVSEQLSLKLPSNVVKES-----ARASFSVLGDILGS----A 964
G I +E+ + + ++ N++ + R + S D LGS +
Sbjct: 937 GAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALS 996
Query: 965 MQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQ---LTQEIKAKAVGYLITGYQRQ 1021
+ +LL++P GCGEQ M+ AP + YL++T+Q L E K AV + GY R
Sbjct: 997 PGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRI 1056
Query: 1022 LNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQK 1081
++ DGSY+ + R +TWLTAFVLK + A+ + + ++ WL Q+
Sbjct: 1057 QQFRKADGSYAAWLSR----GSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQ 1112
Query: 1082 DNGCFRSSGSLLNNAIKGGV---EDEATLSAYVTIALL--------EIPLPVTNPIVRNA 1130
+G F+ +++ +++GG+ ++ L+A+VTIAL E P+ + +
Sbjct: 1113 ADGSFQDLSPVIHRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASI 1172
Query: 1131 LFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREIL-NSLDKEAVKEDNLVHW 1189
A G G+H A+ AYA +L R + N+L A + + ++W
Sbjct: 1173 SKASSFLGEKASAGLLGAH--AAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYW 1230
Query: 1190 --------------ERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLT 1235
P+ P P+ QAP+ +E T+Y LL L + G
Sbjct: 1231 GSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHE-----GKAE 1280
Query: 1236 SATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVT---------- 1285
A W+ +Q + QGGF STQDTV+AL ALS Y A+ T E+ VT
Sbjct: 1281 MADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFK 1340
Query: 1286 -----------------VQDSQTFSTNFQVDNN-----------NLLLLQQISLPELPGE 1317
+Q S N +V N N+L ++ + +L E
Sbjct: 1341 SHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIE 1400
Query: 1318 YVITVTGERCVYLQTS-----MKYNILPEKEDSPFALKVQTVPQTCDGHK---------- 1362
+TV G ++ + +Y+ LP K+D L+ T Q +G +
Sbjct: 1401 --VTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKV 1458
Query: 1363 ---AHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSS--VSRTEVS 1417
+ ++ I G S M I DV ++SGF L+ ++ L S VS E
Sbjct: 1459 VEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETE 1518
Query: 1418 NNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAP 1472
HVL+Y + V F +Q++PVG ++PA +YDYY + Y AP
Sbjct: 1519 GPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
Score = 83.6 bits (205), Expect = 1e-15
Identities = 152/661 (22%), Positives = 263/661 (39%), Gaps = 95/661 (14%)
Query: 27 EPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSL--------FTDLVA 78
+P+ ++ PS++H P V L + V S+ +R+ FT L +
Sbjct: 20 KPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFT-LSS 78
Query: 79 EKDLFHCVSFTLPRISASSEVAFLSIQIKGPT----------QDFRKRNT------VLVL 122
E+D F +S +P A S L ++GP +D R T +L
Sbjct: 79 ERD-FALLSLQVPLKDAKS--CGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFS 135
Query: 123 NTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKL 182
+ + +F+QTD+P+Y PGQ VR+RV ++D+ RP + I + +EN R+ + + + +
Sbjct: 136 SRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTI-TVMVENSHGLRVRK-KEVYM 193
Query: 183 EAGINQLSFPLSSEPIQGSYRVVVQTESG--GRIQHPFTVEEFVLPKFEVKVQ--VPKII 238
+ I Q F + G++++ + G F V+++VLP FEVK+ P I+
Sbjct: 194 PSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYIL 253
Query: 239 SIMD--EKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEV----CEEFSQQLN- 291
++ +++ + + Y YGKPV G+A V +L+ D ++ E ++ +N
Sbjct: 254 TVPGHLDEMQLDIQARYIYGKPVQGVAYVRF-----GLLDEDGKKTFFRGLESQTKLVNG 308
Query: 292 -SNGCITQQVHTKMLQITNTGFE----MKLRVEARIREE-GTDLEVTANRISEITNIVSK 345
S+ +++ L+ N G ++L V A I E G ++E +
Sbjct: 309 QSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFS 368
Query: 346 LKFVKVDSHFRQGIPFFAQVLLVD-----GKGVPIPNKLFFISVNDANYYSNATTNEQGL 400
L K H G PF Q L+ + G+P+ S + N G
Sbjct: 369 LDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGS 428
Query: 401 AQFSIN---TTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHL 457
Q SI +IS +L V + HP + A+ T S ++ +
Sbjct: 429 GQVSIPIIIPQTISELQLSVSAGSPHPAI-------------ARLTVAAPPSGGPGFLSI 475
Query: 458 EPVAGTLPCGHTETITAHYTLNRQAMGELSELS-FHYLIMAKGVIV---RSGTHTLPVES 513
E P + LN +A+G + S ++Y+I+++G IV R TL
Sbjct: 476 E-----RPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLT--- 527
Query: 514 GDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPA-Q 572
++S V+ +AP F D V K++LS A Q
Sbjct: 528 -------SVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQ 580
Query: 573 SPPASHAHLQVAAAPQSLCALRAVDQSVLL--MKPEAELSVSSVYNLLTVKDLTNFPDNV 630
L + +L AL A+D ++ K L++ V+ + DL P
Sbjct: 581 YRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGG 640
Query: 631 D 631
D
Sbjct: 641 D 641
>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
sapiens]
Length = 1744
Score = 236 bits (602), Expect = 1e-61
Identities = 228/835 (27%), Positives = 359/835 (42%), Gaps = 134/835 (16%)
Query: 737 VRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQ 796
VRS+FPE W+W + V+ + + + +PD++T W+ LS+ GL +++ LR F+
Sbjct: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
Query: 797 PFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGEESYCICG 856
F + L +P SV R E L+ + NYL K + VSV + SP E C+ G
Sbjct: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHV--SPV----------EGLCLAG 879
Query: 857 NERQTLSWTVTPKTLGNVNFSV--SAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAE 914
V + V FSV +A A SL++ E P D V K L +E E
Sbjct: 880 GGGLAQQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPV---GDAVSKVLQIEKE 936
Query: 915 G-IEQEKTFSSMTCASGANVSEQLSLKLPSNVVKES-----ARASFSVLGDILGS----A 964
G I +E+ + + ++ N++ + R + S D LGS +
Sbjct: 937 GAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALS 996
Query: 965 MQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQ---LTQEIKAKAVGYLITGYQRQ 1021
+ +LL++P GCGEQ M+ AP + YL++T+Q L E K AV + GY R
Sbjct: 997 PGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRI 1056
Query: 1022 LNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQK 1081
++ DGSY+ + R +TWLTAFVLK + A+ + + ++ WL Q+
Sbjct: 1057 QQFRKADGSYAAWLSR----DSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQ 1112
Query: 1082 DNGCFRSSGSLLNNAIKGGV---EDEATLSAYVTIALL--------EIPLPVTNPIVRNA 1130
+G F+ +L+ +++GG+ ++ L+A+VTIAL E P+ + +
Sbjct: 1113 ADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASI 1172
Query: 1131 LFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREIL-NSLDKEAVKEDNLVHW 1189
A G G+H A+ AYA +L + N+L A + + ++W
Sbjct: 1173 SKANSFLGEKASAGLLGAH--AAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYW 1230
Query: 1190 --------------ERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLT 1235
P+ P P+ QAP+ +E T+Y LL L + G
Sbjct: 1231 GSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHE-----GKAE 1280
Query: 1236 SATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVT---------- 1285
A W+ +Q + QGGF STQDTV+AL ALS Y A+ T E+ VT
Sbjct: 1281 MADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFK 1340
Query: 1286 -----------------VQDSQTFSTNFQVDNN-----------NLLLLQQISLPELPGE 1317
+Q S N +V N N+L ++ + +L E
Sbjct: 1341 SHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIE 1400
Query: 1318 YVITVTGERCVYLQTS-----MKYNILPEKEDSPFALKVQTVPQTCDGHK---------- 1362
+TV G ++ + +Y+ LP K+D L+ T Q +G +
Sbjct: 1401 --VTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKV 1458
Query: 1363 ---AHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSS--VSRTEVS 1417
+ ++ I G S M I DV ++SGF L+ ++ L S VS E
Sbjct: 1459 VEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETE 1518
Query: 1418 NNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAP 1472
HVL+Y + V F +Q++PVG ++PA +YDYY + Y AP
Sbjct: 1519 GPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573
Score = 83.2 bits (204), Expect = 2e-15
Identities = 152/661 (22%), Positives = 263/661 (39%), Gaps = 95/661 (14%)
Query: 27 EPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSL--------FTDLVA 78
+P+ ++ PS++H P V L + V S+ +R+ FT L +
Sbjct: 20 KPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFT-LSS 78
Query: 79 EKDLFHCVSFTLPRISASSEVAFLSIQIKGPT----------QDFRKRNT------VLVL 122
E+D F +S +P A S L ++GP +D R T +L
Sbjct: 79 ERD-FALLSLQVPLKDAKS--CGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFS 135
Query: 123 NTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKL 182
+ + +F+QTD+P+Y PGQ VR+RV ++D+ RP + I + +EN R+ + + + +
Sbjct: 136 SRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTI-TVMVENSHGLRVRK-KEVYM 193
Query: 183 EAGINQLSFPLSSEPIQGSYRVVVQTESG--GRIQHPFTVEEFVLPKFEVKVQ--VPKII 238
+ I Q F + G++++ + G F V+++VLP FEVK+ P I+
Sbjct: 194 PSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYIL 253
Query: 239 SIMD--EKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEV----CEEFSQQLN- 291
++ +++ + + Y YGKPV G+A V +L+ D ++ E ++ +N
Sbjct: 254 TVPGHLDEMQLDIQARYIYGKPVQGVAYVRF-----GLLDEDGKKTFFRGLESQTKLVNG 308
Query: 292 -SNGCITQQVHTKMLQITNTGFE----MKLRVEARIRE-EGTDLEVTANRISEITNIVSK 345
S+ +++ L+ N G ++L V A I E G ++E +
Sbjct: 309 QSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFS 368
Query: 346 LKFVKVDSHFRQGIPFFAQVLLVD-----GKGVPIPNKLFFISVNDANYYSNATTNEQGL 400
L K H G PF Q L+ + G+P+ S + N G
Sbjct: 369 LDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGS 428
Query: 401 AQFSIN---TTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHL 457
Q SI +IS +L V + HP + A+ T S ++ +
Sbjct: 429 GQVSIPIIIPQTISELQLSVSAGSPHPAI-------------ARLTVAAPPSGGPGFLSI 475
Query: 458 EPVAGTLPCGHTETITAHYTLNRQAMGELSELS-FHYLIMAKGVIV---RSGTHTLPVES 513
E P + LN +A+G + S ++Y+I+++G IV R TL
Sbjct: 476 E-----WPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLT--- 527
Query: 514 GDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPA-Q 572
++S V+ +AP F D V K++LS A Q
Sbjct: 528 -------SVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQ 580
Query: 573 SPPASHAHLQVAAAPQSLCALRAVDQSVLL--MKPEAELSVSSVYNLLTVKDLTNFPDNV 630
L + +L AL A+D ++ K L++ V+ + DL P
Sbjct: 581 YRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGG 640
Query: 631 D 631
D
Sbjct: 641 D 641
>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
sapiens]
Length = 1698
Score = 228 bits (581), Expect = 3e-59
Identities = 213/789 (26%), Positives = 350/789 (44%), Gaps = 88/789 (11%)
Query: 737 VRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQ 796
VRS+FPE W+W + V+ + + + +PD++T W+ LS+ GL +++ LR F+
Sbjct: 774 VRSFFPENWLWRVETVDRFQI--LTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFR 831
Query: 797 PFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGEESYCICG 856
F + L +P SV R E L+ + NYL K + VSV + SP E C+ G
Sbjct: 832 EFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHV--SPV----------EGLCLAG 879
Query: 857 NERQTLSWTVTPKTLGNVNFSV--SAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAE 914
V + V FSV +A A SL++ E P D V K L +E E
Sbjct: 880 GGGLAQQVLVPAGSARPVAFSVVPTAAAAVSLKVVARGSFEFPV---GDAVSKVLQIEKE 936
Query: 915 G-IEQEKTFSSMTCASGANVSEQLSLKLPSNVVKES-----ARASFSVLGDILGS----A 964
G I +E+ + + ++ N++ + R + S D LGS +
Sbjct: 937 GAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALS 996
Query: 965 MQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQ---LTQEIKAKAVGYLITGYQRQ 1021
+ +LL++P GCGEQ M+ AP + YL++T+Q L E K AV + GY R
Sbjct: 997 PGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRI 1056
Query: 1022 LNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQK 1081
++ DGSY+ + R +TWLTAFVLK + A+ + + ++ WL Q+
Sbjct: 1057 QQFRKADGSYAAWLSR----DSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLLSQQQ 1112
Query: 1082 DNGCFRSSGSLLNNAIKGGV---EDEATLSAYVTIALL--------EIPLPVTNPIVRNA 1130
+G F+ +L+ +++GG+ ++ L+A+VTIAL E P+ + +
Sbjct: 1113 ADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASI 1172
Query: 1131 LFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREIL-NSLDKEAVKEDNLVHW 1189
A G G+H A+ AYA +L + N+L A + + ++W
Sbjct: 1173 SKANSFLGEKASAGLLGAH--AAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYW 1230
Query: 1190 --------------ERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLT 1235
P+ P P+ QAP+ +E T+Y LL L + G
Sbjct: 1231 GSVTGSQSNAVSPTPAPRNPSDPM-----PQAPALWIETTAYALLHLLLHE-----GKAE 1280
Query: 1236 SATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVTVQDS--QTFS 1293
A W+ +Q + QGGF STQDTV+AL ALS Y A+ T E+ VT+ + F
Sbjct: 1281 MADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFK 1340
Query: 1294 TN-FQVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKEDSPFALKVQ 1352
++ Q++N + L++ L + + V G L+ YN+L K + L+++
Sbjct: 1341 SHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIE 1400
Query: 1353 T-----VPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLK----PTVK 1403
V T + ++ + ++ + + A + +++ G + P +
Sbjct: 1401 VTVKGHVEYTMEANEDYEDYEYD-ELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKLT 1459
Query: 1404 MLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDE 1463
L VS E HVL+Y + V F +Q++PVG ++PA +YDYY +
Sbjct: 1460 SLS-DRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPER 1518
Query: 1464 SVVAEYIAP 1472
Y AP
Sbjct: 1519 RCSVFYGAP 1527
Score = 83.2 bits (204), Expect = 2e-15
Identities = 152/661 (22%), Positives = 263/661 (39%), Gaps = 95/661 (14%)
Query: 27 EPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRSL--------FTDLVA 78
+P+ ++ PS++H P V L + V S+ +R+ FT L +
Sbjct: 20 KPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFT-LSS 78
Query: 79 EKDLFHCVSFTLPRISASSEVAFLSIQIKGPT----------QDFRKRNT------VLVL 122
E+D F +S +P A S L ++GP +D R T +L
Sbjct: 79 ERD-FALLSLQVPLKDAKS--CGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFS 135
Query: 123 NTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKL 182
+ + +F+QTD+P+Y PGQ VR+RV ++D+ RP + I + +EN R+ + + + +
Sbjct: 136 SRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTI-TVMVENSHGLRVRK-KEVYM 193
Query: 183 EAGINQLSFPLSSEPIQGSYRVVVQTESG--GRIQHPFTVEEFVLPKFEVKVQ--VPKII 238
+ I Q F + G++++ + G F V+++VLP FEVK+ P I+
Sbjct: 194 PSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYIL 253
Query: 239 SIMD--EKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEV----CEEFSQQLN- 291
++ +++ + + Y YGKPV G+A V +L+ D ++ E ++ +N
Sbjct: 254 TVPGHLDEMQLDIQARYIYGKPVQGVAYVRF-----GLLDEDGKKTFFRGLESQTKLVNG 308
Query: 292 -SNGCITQQVHTKMLQITNTGFE----MKLRVEARIRE-EGTDLEVTANRISEITNIVSK 345
S+ +++ L+ N G ++L V A I E G ++E +
Sbjct: 309 QSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIEYPGGEMEEAELTSWYFVSSPFS 368
Query: 346 LKFVKVDSHFRQGIPFFAQVLLVD-----GKGVPIPNKLFFISVNDANYYSNATTNEQGL 400
L K H G PF Q L+ + G+P+ S + N G
Sbjct: 369 LDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGS 428
Query: 401 AQFSIN---TTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHL 457
Q SI +IS +L V + HP + A+ T S ++ +
Sbjct: 429 GQVSIPIIIPQTISELQLSVSAGSPHPAI-------------ARLTVAAPPSGGPGFLSI 475
Query: 458 EPVAGTLPCGHTETITAHYTLNRQAMGELSELS-FHYLIMAKGVIV---RSGTHTLPVES 513
E P + LN +A+G + S ++Y+I+++G IV R TL
Sbjct: 476 E-----WPDSRPPRVGDTLNLNLRAVGSGATFSHYYYMILSRGQIVFMNREPKRTLT--- 527
Query: 514 GDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDLSFSPA-Q 572
++S V+ +AP F D V K++LS A Q
Sbjct: 528 -------SVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQ 580
Query: 573 SPPASHAHLQVAAAPQSLCALRAVDQSVLL--MKPEAELSVSSVYNLLTVKDLTNFPDNV 630
L + +L AL A+D ++ K L++ V+ + DL P
Sbjct: 581 YRNGESVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGG 640
Query: 631 D 631
D
Sbjct: 641 D 641
>gi|115298678 complement component 3 precursor [Homo sapiens]
Length = 1663
Score = 202 bits (514), Expect = 2e-51
Identities = 198/782 (25%), Positives = 350/782 (44%), Gaps = 102/782 (13%)
Query: 738 RSYFPETWIWELVAV-----NSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 792
RS FPE+W+W + + N + + + D+IT W+ A +S+ G+ ++ +
Sbjct: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEV 823
Query: 793 RAFQPFFVELTMPYSVIRGEVFTLKATVLNYLP-KCIRVSVQLKASPAFLASQNTKGEES 851
Q FF++L +PYSV+R E ++A + NY + ++V V+L +PAF + TK
Sbjct: 824 TVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQ 883
Query: 852 YCICGNERQTLS--WTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTL 909
+ + +LS + + P G V A D V K+L
Sbjct: 884 QTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF--------------ISDGVRKSL 929
Query: 910 LVEAEGIEQEKTFSSMTC------ASGANVSE----QLSLKLPSNVVKESARASFSVLGD 959
V EGI KT + T G + LS ++P + + +
Sbjct: 930 KVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQ 989
Query: 960 ILGSAM--QNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQ---EIKAKAVGYL 1014
+ A+ + +++L+ P GCGEQNM+ P + ++YL+ET+Q + E + A+ +
Sbjct: 990 MTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELI 1049
Query: 1015 ITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLT 1074
GY +QL ++ +++ F +R +TWLTA+V+K F+ A + I ID + ++
Sbjct: 1050 KKGYTQQLAFRQPSSAFAAFVKR----APSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVK 1105
Query: 1075 WL-SQMQKDNGCFRSSGSLLNNAIKGGV----EDEATLSAYVTIALLEIPLPVTNPIVRN 1129
WL + QK +G F+ +++ + GG+ E + L+A+V I+L E I
Sbjct: 1106 WLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQE-----AKDICEE 1160
Query: 1130 ALFCLESAWNVAKEGTHGSHV-----YTKALLAYAFSLLGKQN---QNREILNSLDKEAV 1181
+ L + A + +++ YT A+ YA + +G+ N+ + + DK
Sbjct: 1161 QVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKN-- 1218
Query: 1182 KEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIV 1241
WE P + LY VE TSY LLA L + D +V
Sbjct: 1219 ------RWEDPGK------QLY-------NVEATSYALLALLQLK------DFDFVPPVV 1253
Query: 1242 KWIMKQQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVTVQ-DSQTFSTNFQVDN 1300
+W+ +Q+ GG+ STQ T + AL++Y E V++Q S++ ++
Sbjct: 1254 RWLNEQRYYGGGYGSTQATFMVFQALAQYQKDAPDHQELNLDVSLQLPSRSSKITHRIHW 1313
Query: 1301 NNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKE--DSPFALKV--QTVPQ 1356
+ LL+ E G + +T G+ L Y+ + + + F LKV + P+
Sbjct: 1314 ESASLLRSEETKENEG-FTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTIKPAPE 1372
Query: 1357 T-CDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSS--VSR 1413
T A + + + Y G++ A+ M I+D+ M++GF P +K L +S+
Sbjct: 1373 TEKRPQDAKNTMILEICTRYRGDQDAT-MSILDISMMTGFAPDTDDLKQLANGVDRYISK 1431
Query: 1414 TEV-----SNNHVLIYVEQVT-NQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVA 1467
E+ N ++IY+++V+ ++ +F V Q V ++P VKVY YY +ES
Sbjct: 1432 YELDKAFSDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTR 1491
Query: 1468 EY 1469
Y
Sbjct: 1492 FY 1493
Score = 116 bits (291), Expect = 1e-25
Identities = 156/650 (24%), Positives = 272/650 (41%), Gaps = 72/650 (11%)
Query: 13 LLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSH-----LNETVTVSASLESGR 67
LLL+LL+ P Y ++ P++L E+ ++ VL +H + TVTV
Sbjct: 9 LLLLLLTHLPLALGSPMYSIITPNILRLES-EETMVLEAHDAQGDVPVTVTVHDFPGKKL 67
Query: 68 ENRSLFTDLVAEKDLFHCVSFTLPRI----SASSEVAFLSIQIKGPTQDFRKRNTVLVLN 123
S T L + V+FT+P S F+++Q TQ K VLV
Sbjct: 68 VLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEK--VVLVSL 125
Query: 124 TQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQ-SLKL 182
+F+QTDK +Y PG TV +R+ +V+ P + ++ +ENP + Q S +
Sbjct: 126 QSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTV-MVNIENPEGIPVKQDSLSSQN 184
Query: 183 EAGINQLSFPLSSEPIQGSYRVVVQTESGGR--IQHPFTVEEFVLPKFEVKVQ-VPKIIS 239
+ G+ LS+ + G +++ E+ + F V+E+VLP FEV V+ K
Sbjct: 185 QLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYY 244
Query: 240 IMDEK-VNITVCGEYTYGKPVPGLATV-----------SLCRKLSRVLNCD-------KQ 280
I +EK + +T+ + YGK V G A V SL L R+ D +
Sbjct: 245 IYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSR 304
Query: 281 EVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEIT 340
+V + Q + + + ++ I ++G +M ++ E + + + +
Sbjct: 305 KVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDM-------VQAERSGIPIVTSPY---- 353
Query: 341 NIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGL 400
++ F K +F+ G+PF V + + G P + D + T G+
Sbjct: 354 ----QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDT---VQSLTQGDGV 406
Query: 401 AQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPV 460
A+ SINT S L + V T L S + + Q S +Y+HL +
Sbjct: 407 AKLSINTHP-SQKPLSITVRTKKQEL----SEAEQATRTMQALPYSTVGNSNNYLHLSVL 461
Query: 461 AGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSF 520
L G ET+ ++ L E + YLIM KG ++++G E G +
Sbjct: 462 RTELRPG--ETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVR--EPG--QDLV 515
Query: 521 ALSFPVESDVAPIARMFIFAIL----PDGEVVGDSEKFEI-ENCLANKVDLS--FSPAQS 573
L + +D P R+ + L EVV DS ++ ++C+ + V S Q
Sbjct: 516 VLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQP 575
Query: 574 PPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDL 623
P L++ + L AVD+ V ++ + +L+ S +++++ D+
Sbjct: 576 VPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADI 625
>gi|38016947 complement component 5 preproprotein [Homo sapiens]
Length = 1676
Score = 186 bits (473), Expect = 1e-46
Identities = 188/791 (23%), Positives = 340/791 (42%), Gaps = 104/791 (13%)
Query: 737 VRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQ 796
+RSYFPE+W+WE+ V ++ +PD++T W+ +S + G+ ++ T + F+
Sbjct: 765 IRSYFPESWLWEVHLVPRR--KQLQFALPDSLTTWEIQGVGIS-NTGICVADTVKAKVFK 821
Query: 797 PFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLAS-------QNTKGE 849
F+E+ +PYSV+RGE LK TV NY ++ V++ A S Q TK
Sbjct: 822 DVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTK-- 879
Query: 850 ESYCIC----GNERQTLSWTVTPKTLG--NVNFSVSAEAMQSLELCGNEVVEVPEIKRKD 903
S C+ G+ +++TV P +G N+NFS+ K+
Sbjct: 880 SSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWF------------------GKE 921
Query: 904 TVIKTLLVEAEGIEQEK----TFSSMTCASGANVSEQLSLKLPSNVV-KESARASFSVLG 958
++KTL V EG+++E T + ++ ++P ++V K + SV G
Sbjct: 922 ILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKG 981
Query: 959 DILGS------AMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLN--------ETQQLTQ 1004
++G + + I L +P G E ++ P YV +YL + L +
Sbjct: 982 LLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIE 1041
Query: 1005 EIKAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFI 1064
+ K K L G ++Y++ D SYS + +TWLTAF L+ Q Y+
Sbjct: 1042 KQKLKK--KLKEGMLSIMSYRNADYSYSV----WKGGSASTWLTAFALRVLGQVNKYVEQ 1095
Query: 1065 DEAHITQSLTWL-SQMQKDNGCFRSSGSLLNNAIKGGVEDEAT-----LSAYVTIALLE- 1117
++ I SL WL Q DNG F+ + ++G + EA L+A+ I + +
Sbjct: 1096 NQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKA 1155
Query: 1118 ---IPL-PVTNPIVRNALFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQN-QNREI 1172
PL + +++ F LE+ +T A+ AYA SL K + Q R I
Sbjct: 1156 FDICPLVKIDTALIKADNFLLENT-------LPAQSTFTLAISAYALSLGDKTHPQFRSI 1208
Query: 1173 LNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSG 1232
+++L +EA+ + N + + + VE T+Y LL L +
Sbjct: 1209 VSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLNLK------ 1262
Query: 1233 DLTSATNIVKWIMKQQNAQGGFSSTQDTVVALHALSRYG-AATFTRTEKTAQVTVQDSQT 1291
D+ ++KW+ ++Q GGF STQDT+ A+ L+ Y R V+ +
Sbjct: 1263 DINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGA 1322
Query: 1292 FSTNFQVDNNNLLLLQQISLPELPGEYVITV---TGERCVYLQTSMKYNILPEKEDSPFA 1348
D N L ++ L + + +++ +G V++ T++ + +E F
Sbjct: 1323 LHNYKMTDKNFLGRPVEVLLND---DLIVSTGFGSGLATVHV-TTVVHKTSTSEEVCSFY 1378
Query: 1349 LKVQTVPQTCDGHKAHTSFQISLTISYTGNRPA-------SNMVIVDVKMVSGFIPLKPT 1401
LK+ T ++ + + ++ +P+ S+ ++D+ + +G +
Sbjct: 1379 LKIDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEED 1438
Query: 1402 VKMLERSSSVSRT--EVSNNHVLIYVEQV-TNQTLSFSFMVLQDIPVGDLKPAIVKVYDY 1458
+K L T ++ + HV++ + + ++ L F + + VG L PA VY+Y
Sbjct: 1439 LKALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEY 1498
Query: 1459 YETDESVVAEY 1469
+ D+ Y
Sbjct: 1499 HRPDKQCTMFY 1509
Score = 105 bits (261), Expect = 4e-22
Identities = 143/646 (22%), Positives = 266/646 (41%), Gaps = 50/646 (7%)
Query: 11 LVLLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENR 70
L +L L+ + E Y++ P + A + + + E + S++S + +
Sbjct: 4 LGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDKK 63
Query: 71 SLFTD----LVAEKDLFHCVSFTL-PRISASSEVAFLSIQIKGPTQDFRKRNTVLVLNTQ 125
++ L +E + T+ P+ + + ++ ++ F K + +
Sbjct: 64 FSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDN 123
Query: 126 SLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAG 185
+F+ TDKP+Y P Q+V+ RV S++++ +P L +++ P + + + +
Sbjct: 124 GFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFID-PEGSEVDMVEEIDHIGI 182
Query: 186 INQLSFPLSSEPIQGSYRVVVQTESGGRIQHP--FTVEEFVLPKFEVKVQVP-KIISIMD 242
I+ F + S P G + + + + F V+E+VLP F V ++ I +
Sbjct: 183 ISFPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKN 242
Query: 243 EK-VNITVCGEYTYGKPVPGLATVSLCRKLSRVLNCDKQEVCEEFSQQ---LNSNGCITQ 298
K IT+ Y Y K V A V + + L D++E+ + Q +N +T
Sbjct: 243 FKNFEITIKARYFYNKVVTE-ADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTF 301
Query: 299 QVHTKMLQITNTGFE----MKLRVEARIREEGTDLEVTANRISEITNIVS--KLKFVKVD 352
T + +++ E L + + E A I I ++S KL V
Sbjct: 302 DSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEA-EIPGIKYVLSPYKLNLVATP 360
Query: 353 SHFRQGIPFFAQVLLVDG-----KGVPIPNKLFFISVN----DANYYSNATTNEQGLAQF 403
+ GIP+ +V + D GVP+ I VN D + + T + G+A F
Sbjct: 361 LFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVASF 420
Query: 404 SINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQ-HTANRVFSLSGSYIHLEPVAG 462
+N S V L V T P+L E++Q + + A SLS SY++++
Sbjct: 421 VLNLPS-GVTVLEFNVKTDAPDL-------PEENQAREGYRAIAYSSLSQSYLYIDWTDN 472
Query: 463 TLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFAL 522
E + T + +++ ++YLI++KG I+ GT E ++
Sbjct: 473 HKALLVGEHLNIIVTPKSPYIDKITH--YNYLILSKGKIIHFGTR----EKFSDASYQSI 526
Query: 523 SFPVESDVAPIARMFIFAIL---PDGEVVGDSEKFEIENCLANKVDLSFSPAQS--PPAS 577
+ PV ++ P +R+ ++ I+ E+V DS IE N++ + SP P
Sbjct: 527 NIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYSPGQ 586
Query: 578 HAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDL 623
L +A S AL AVD +V ++ A+ + V+ L DL
Sbjct: 587 TVSLNMATGMDSWVALAAVDSAVYGVQRGAKKPLERVFQFLEKSDL 632
>gi|169218213 PREDICTED: similar to complement component C3, partial
[Homo sapiens]
Length = 1295
Score = 169 bits (428), Expect = 2e-41
Identities = 147/569 (25%), Positives = 256/569 (44%), Gaps = 86/569 (15%)
Query: 738 RSYFPETWIWELVAV-----NSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASL 792
RS FPE+W+W + + N + + + D+IT W+ A +S+ G+ ++ +
Sbjct: 764 RSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGICVADPFEV 823
Query: 793 RAFQPFFVELTMPYSVIRGEVFTLKATVLNYLP-KCIRVSVQLKASPAFLASQNTKGEES 851
Q FF++L +PYSV+R E ++A + NY + ++V V+L +PAF + TK
Sbjct: 824 TVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAFCSLATTKRRHQ 883
Query: 852 YCICGNERQTLS--WTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTL 909
+ + +LS + + P G V A D V K+L
Sbjct: 884 QTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHF--------------ISDGVRKSL 929
Query: 910 LVEAEGIEQEKTFSSMTC------ASGANVSE----QLSLKLPSNVVKESARASFSVLGD 959
V EGI KT + T G + LS ++P + + +
Sbjct: 930 KVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPDTESETRILLQGTPVAQ 989
Query: 960 ILGSAM--QNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQ---EIKAKAVGYL 1014
+ A+ + +++L+ P GCGEQNM+ P + ++YL+ET+Q + E + A+ +
Sbjct: 990 MTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEKFGLEKRQGALELI 1049
Query: 1015 ITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLT 1074
GY +QL ++ +++ F +R +TWLTA+V+K F+ A + I ID + ++
Sbjct: 1050 KKGYTQQLAFRQPSSAFAAFVKR----APSTWLTAYVVKVFSLAVNLIAIDSQVLCGAVK 1105
Query: 1075 WL-SQMQKDNGCFRSSGSLLNNAIKGGV----EDEATLSAYVTIALLEIPLPVTNPIVRN 1129
WL + QK +G F+ +++ + GG+ E + L+A+V I+L E I
Sbjct: 1106 WLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISLQE-----AKDICEE 1160
Query: 1130 ALFCLESAWNVAKEGTHGSHV-----YTKALLAYAFSLLGKQN---QNREILNSLDKEAV 1181
+ L + A + +++ YT A+ YA + +G+ N+ + + DK
Sbjct: 1161 QVNSLPGSITKAGDFLEANYMNLQRSYTVAIAGYALAQMGRLKGPLLNKFLTTAKDKN-- 1218
Query: 1182 KEDNLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIV 1241
WE P + LY VE TSY LLA L + D +V
Sbjct: 1219 ------RWEDPGK------QLY-------NVEATSYALLALLQLK------DFDFVPPVV 1253
Query: 1242 KWIMKQQNAQGGFSSTQDTVVALHALSRY 1270
+W+ +Q+ GG+ STQ T + AL++Y
Sbjct: 1254 RWLNEQRYYGGGYGSTQATFMVFQALAQY 1282
Score = 119 bits (298), Expect = 2e-26
Identities = 156/650 (24%), Positives = 273/650 (42%), Gaps = 72/650 (11%)
Query: 13 LLLILLSASDSNSTEPQYMVLVPSLLHTEAPKKGCVLLSH-----LNETVTVSASLESGR 67
LLL+LL+ P Y ++ P++L E+ ++ VL +H + TVTV
Sbjct: 9 LLLLLLTHLPLALGSPMYSIITPNILRLES-EETMVLEAHDAQGDVPVTVTVHDFPGKKL 67
Query: 68 ENRSLFTDLVAEKDLFHCVSFTLPRI----SASSEVAFLSIQIKGPTQDFRKRNTVLVLN 123
S T L + V+FT+P S F+++Q TQ K VLV
Sbjct: 68 VLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQATFGTQVVEK--VVLVSL 125
Query: 124 TQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQ-SLKL 182
+F+QTDK +Y PG TV +R+ +V+ P + ++ +ENP + Q S +
Sbjct: 126 QSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVGRTV-MVNIENPEGIPVKQDSLSSQN 184
Query: 183 EAGINQLSFPLSSEPIQGSYRVVVQTESGGR--IQHPFTVEEFVLPKFEVKVQ-VPKIIS 239
+ G+ LS+ + G +++ E+ + F V+E+VLP FEV V+ K
Sbjct: 185 QLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEVIVEPTEKFYY 244
Query: 240 IMDEK-VNITVCGEYTYGKPVPGLA-----------TVSLCRKLSRVLNCD-------KQ 280
I +EK + +T+ + YGK V G A +SL L R+ D +
Sbjct: 245 IYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVLSR 304
Query: 281 EVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTANRISEIT 340
+V + Q L + + + ++ I ++G +M ++ E + + + +
Sbjct: 305 KVLLDGVQNLRAEDLVGKSLYVSATVILHSGSDM-------VQAERSGIPIVTSPY---- 353
Query: 341 NIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFISVNDANYYSNATTNEQGL 400
++ F K +F+ G+PF V + + G P + D + T G+
Sbjct: 354 ----QIHFTKTPKYFKPGMPFDLMVFVTNPDGSPAYRVPVAVQGEDT---VQSLTQGDGV 406
Query: 401 AQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPV 460
A+ SINT S L + V T L S + + Q S +Y+HL +
Sbjct: 407 AKLSINTHP-SQKPLSITVRTKKQEL----SEAEQATRTMQALPYSTVGNSNNYLHLSVL 461
Query: 461 AGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSF 520
L G ET+ ++ L E + YLIM KG ++++G E G +
Sbjct: 462 RTELRPG--ETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLKAGRQVR--EPG--QDLV 515
Query: 521 ALSFPVESDVAPIARMFIFAIL----PDGEVVGDSEKFEI-ENCLANKVDLS--FSPAQS 573
L + +D P R+ + L EVV DS ++ ++C+ + V S Q
Sbjct: 516 VLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSLVVKSGQSEDRQP 575
Query: 574 PPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDL 623
P L++ + L AVD+ V ++ + +L+ S +++++ D+
Sbjct: 576 VPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEKADI 625
>gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 261
Score = 160 bits (405), Expect = 8e-39
Identities = 85/241 (35%), Positives = 138/241 (57%), Gaps = 2/241 (0%)
Query: 377 NKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAED 436
NKL + +ND + N TT+E G AQFSI+T+ I + ++ V P C+ SW+
Sbjct: 3 NKLLQLELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQ 61
Query: 437 HQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIM 496
+ A +R +S + S++ + P L C H + +T HY+LN +A + S + F YL
Sbjct: 62 YLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLCT 121
Query: 497 AKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEI 556
+ + + P+ + G+F+ + +D+AP A +F++ + P GE+V DS +F++
Sbjct: 122 SDSGNFQHRISSSPIYTA-WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 180
Query: 557 ENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYN 616
+ C +KV++ FS Q P S+A L + AAP CALRAVD++VLL+K E +LS SV +
Sbjct: 181 DKCFKHKVNIKFSNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESVSS 240
Query: 617 L 617
L
Sbjct: 241 L 241
>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 278
Score = 145 bits (366), Expect = 3e-34
Identities = 82/207 (39%), Positives = 118/207 (57%), Gaps = 9/207 (4%)
Query: 669 MGLKVFTNSKIRKPKSCSV---IPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLN 725
MGLKVFTN RKP+ C + +P + YG V R + + + N
Sbjct: 1 MGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMRSVPSR-----IASSGIRGEN 55
Query: 726 NEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLG 785
+ + +TVR+ FPETW+W+LV+V+SSG A + +PDTIT+W+A FC++ D G G
Sbjct: 56 ADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFG 115
Query: 786 ISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQN 845
ISST +L QPFF+E+ P+SV++ E F L V +Y C+ +SVQ++ S + A+ N
Sbjct: 116 ISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANIN 175
Query: 846 T-KGEESYCICGNERQTLSWTVTPKTL 871
T K S I R+T WT+ PK L
Sbjct: 176 TWKINGSEVIQAGGRKTNIWTIIPKKL 202
>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
Length = 257
Score = 141 bits (355), Expect = 5e-33
Identities = 75/195 (38%), Positives = 119/195 (61%), Gaps = 5/195 (2%)
Query: 1284 VTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKE 1343
V+ S+ S FQV+ +N LL+Q+ + + PG+Y + V G C ++Q ++KYN+L K+
Sbjct: 68 VSASRSEGSSEIFQVNGHNRLLVQRSEVTQAPGQYTVDVEGHGCTFIQATLKYNVLLPKK 127
Query: 1344 DSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVK 1403
S F+L ++ V + + T+F +++T+ YTG R S+MV++DVKM+SGF P +++
Sbjct: 128 ASGFSLSLEIVK-----NYSSTAFDLTVTLKYTGIRNKSSMVVIDVKMLSGFTPTMSSIE 182
Query: 1404 MLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDE 1463
LE V +TEV N+HVL Y+E + SF F V Q V +++PA VYDYYE +E
Sbjct: 183 ELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSNLVFNIQPAPAMVYDYYEKEE 242
Query: 1464 SVVAEYIAPCSTDTE 1478
+A Y S+ +E
Sbjct: 243 YALAFYNIDSSSVSE 257
>gi|239758130 PREDICTED: similar to complement component 4B (Childo
blood group), partial [Homo sapiens]
Length = 666
Score = 124 bits (310), Expect = 9e-28
Identities = 130/509 (25%), Positives = 209/509 (41%), Gaps = 98/509 (19%)
Query: 1048 TAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGV---EDE 1104
TAFVLK + A+ + + ++ WL Q+ +G F+ +++ +++GG+ ++
Sbjct: 1 TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDET 60
Query: 1105 ATLSAYVTIALL--------EIPLPVTNPIVRNALFCLESAWNVAKEGTHGSHVYTKALL 1156
L+A+VTIAL E P+ + + A G G+H A+
Sbjct: 61 VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHA--AAIT 118
Query: 1157 AYAFSLLGKQNQNREIL-NSLDKEAVKEDNLVHW--------------ERPQRPKAPVGH 1201
AYA +L R + N+L A + + ++W P+ P P+
Sbjct: 119 AYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPM-- 176
Query: 1202 LYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTV 1261
QAP+ +E T+Y LL L + D +A W+ +Q + QGGF STQDTV
Sbjct: 177 ---PQAPALWIETTAYALLHLLLHEGKAEMADQAAA-----WLTRQGSFQGGFRSTQDTV 228
Query: 1262 VALHALSRYGAATFTRTEKTAQVT---------------------------VQDSQTFST 1294
+AL ALS Y A+ T E+ VT +Q S
Sbjct: 229 IALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKI 288
Query: 1295 NFQVDNN-----------NLLLLQQISLPELPGEYVITVTGERCVYLQTS-----MKYNI 1338
N +V N N+L ++ + +L E +TV G ++ + +Y+
Sbjct: 289 NVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIE--VTVKGHVEYTMEANEDYEDYEYDE 346
Query: 1339 LPEKEDSPFALKVQTVPQTCDGHK-------------AHTSFQISLTISYTGNRPASNMV 1385
LP K+D L+ T Q +G + + ++ I G S M
Sbjct: 347 LPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMA 406
Query: 1386 IVDVKMVSGFIPLKPTVKMLERSSS--VSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDI 1443
I DV ++SGF L+ ++ L S VS E HVL+Y + V F +Q++
Sbjct: 407 IADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEV 466
Query: 1444 PVGDLKPAIVKVYDYYETDESVVAEYIAP 1472
PVG ++PA +YDYY + Y AP
Sbjct: 467 PVGLVQPASATLYDYYNPERRCSVFYGAP 495
>gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 195
Score = 114 bits (285), Expect = 7e-25
Identities = 58/188 (30%), Positives = 102/188 (54%), Gaps = 2/188 (1%)
Query: 377 NKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAED 436
NKL + +ND + N TT+E G AQFSI+T+ I + ++ V P C+ SW+
Sbjct: 3 NKLLQLELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQ 61
Query: 437 HQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIM 496
+ A +R +S + S++ + P L C H + +T HY+LN +A + S + F YL
Sbjct: 62 YLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLCT 121
Query: 497 AKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEI 556
+ + + P+ + G+F+ + +D+AP A +F++ + P GE+V DS +F++
Sbjct: 122 SDSGNFQHRISSSPIYTA-WNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 180
Query: 557 ENCLANKV 564
+ C +KV
Sbjct: 181 DKCFKHKV 188
>gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sapiens]
Length = 189
Score = 106 bits (265), Expect = 1e-22
Identities = 61/140 (43%), Positives = 88/140 (62%), Gaps = 9/140 (6%)
Query: 1125 PIVRNALFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKED 1184
P +RNALFCLE+A + T+G Y A+LAYAF+L GK+ Q +L +LD+ A K +
Sbjct: 48 PALRNALFCLEAALDSGV--TNG---YNHAILAYAFALAGKEKQVESLLQTLDQSATKLN 102
Query: 1185 NLVHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWI 1244
N+++WER ++PK + APSA+ E + YVLLA ++ + DLT A+ IV+W+
Sbjct: 103 NVIYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRK----IPDLTYASKIVQWL 158
Query: 1245 MKQQNAQGGFSSTQDTVVAL 1264
+Q N+ GGFSS Q V L
Sbjct: 159 AQQMNSHGGFSSNQVINVGL 178
>gi|169217831 PREDICTED: similar to Ovostatin homolog 2 [Homo
sapiens]
Length = 136
Score = 79.0 bits (193), Expect = 3e-14
Identities = 40/119 (33%), Positives = 65/119 (54%), Gaps = 1/119 (0%)
Query: 377 NKLFFISVNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAED 436
NKL + +ND + N TT+E G AQFSI+T+ I + ++ V P C+ SW+
Sbjct: 3 NKLLQLELND-EFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQ 61
Query: 437 HQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLI 495
+ A +R +S + S++ + P L C H + +T HY+LN +A + S + F YL+
Sbjct: 62 YLDAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFYLV 120
>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
Length = 95
Score = 78.2 bits (191), Expect = 6e-14
Identities = 41/95 (43%), Positives = 58/95 (61%)
Query: 1384 MVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDI 1443
MV++DVKM+SGF P +++ LE V +TEV N+HVL Y+E + SF F V Q
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60
Query: 1444 PVGDLKPAIVKVYDYYETDESVVAEYIAPCSTDTE 1478
V +++PA VYDYYE +E +A Y S+ +E
Sbjct: 61 LVFNIQPAPAMVYDYYEKEEYALAFYNIDSSSVSE 95
>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
Length = 95
Score = 77.4 bits (189), Expect = 9e-14
Identities = 39/86 (45%), Positives = 54/86 (62%)
Query: 1384 MVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQDI 1443
MV++DVKM+SGF P +++ LE V +TEV N+HVL Y+E + SF F V Q
Sbjct: 1 MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60
Query: 1444 PVGDLKPAIVKVYDYYETDESVVAEY 1469
V +++PA VYDYYE +E +A Y
Sbjct: 61 LVFNIQPAPAMVYDYYEKEEYALAFY 86
>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
blood group) [Homo sapiens]
Length = 270
Score = 74.3 bits (181), Expect = 8e-13
Identities = 45/144 (31%), Positives = 81/144 (56%), Gaps = 8/144 (5%)
Query: 128 VFVQTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGIN 187
+F+QTD+P+Y PGQ VR+RV ++D+ RP + I + +EN R+ + + + + + I
Sbjct: 61 LFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTI-TVMVENSHGLRVRK-KEVYMPSSIF 118
Query: 188 QLSFPLSSEPIQGSYRVVVQTESG--GRIQHPFTVEEFVLPKFEVKVQ--VPKIISIMD- 242
Q F + G++++ + G F V+++VLP FEVK+ P I+++
Sbjct: 119 QDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGH 178
Query: 243 -EKVNITVCGEYTYGKPVPGLATV 265
+++ + + Y YGKPV G+A V
Sbjct: 179 LDEMQLDIQARYIYGKPVQGVAYV 202
>gi|239755754 PREDICTED: ovostatin 2 [Homo sapiens]
Length = 164
Score = 57.4 bits (137), Expect = 1e-07
Identities = 33/88 (37%), Positives = 46/88 (52%)
Query: 1382 SNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFSFMVLQ 1441
S+ V + ++S P LE V +TEV N+HVL Y+E + SF F V Q
Sbjct: 68 SSAVALSFFLISILYPSLTISSKLENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQ 127
Query: 1442 DIPVGDLKPAIVKVYDYYETDESVVAEY 1469
V +++PA VYDYYE +E +A Y
Sbjct: 128 SNLVFNIQPAPAMVYDYYEKEEYALAFY 155
>gi|169214179 PREDICTED: similar to complement component 3 [Homo
sapiens]
Length = 390
Score = 44.7 bits (104), Expect = 7e-04
Identities = 33/115 (28%), Positives = 59/115 (51%), Gaps = 9/115 (7%)
Query: 1363 AHTSFQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSS--VSRTEVSN-- 1418
A + + + Y G++ A+ M I+D+ M++GF P +K L +S+ E+
Sbjct: 107 AKNTMILEICTRYRGDQDAT-MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAF 165
Query: 1419 ---NHVLIYVEQVTN-QTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEY 1469
N ++IY+++V++ + +F V Q V ++P VKVY YY +ES Y
Sbjct: 166 SDRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFY 220
>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
Length = 2725
Score = 35.0 bits (79), Expect = 0.54
Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 12/82 (14%)
Query: 384 VNDANYYSNATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHT 443
+ND N Y A+ +Q L QF++N T + L R + +++++ +E GA
Sbjct: 1528 LNDMNIYEIASPADQELYQFTVNGTHLHTLNLITRDYV------YNFTYNSEGDLGA--- 1578
Query: 444 ANRVFSLSGSYIHLEPVAGTLP 465
+ S +G+ +H+ AG +P
Sbjct: 1579 ---ITSSNGNSVHIRRDAGGMP 1597
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,059,728
Number of Sequences: 37866
Number of extensions: 2302946
Number of successful extensions: 5241
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 4996
Number of HSP's gapped (non-prelim): 78
length of query: 1482
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1367
effective length of database: 13,892,928
effective search space: 18991632576
effective search space used: 18991632576
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.