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Search of human proteins with 157739930
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157739930 TAP binding protein-like [Homo sapiens]
(468 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157739930 TAP binding protein-like [Homo sapiens] 926 0.0
gi|27436893 tapasin isoform 1 precursor [Homo sapiens] 77 3e-14
gi|27436897 tapasin isoform 3 precursor [Homo sapiens] 74 4e-13
gi|67188443 CD276 antigen isoform a [Homo sapiens] 68 2e-11
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 61 2e-09
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 61 2e-09
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 61 2e-09
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 61 2e-09
gi|13376852 CD276 antigen isoform b [Homo sapiens] 60 6e-09
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 53 5e-07
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 53 5e-07
gi|21040353 hemochromatosis protein isoform 9 precursor [Homo sa... 50 3e-06
gi|21040349 hemochromatosis protein isoform 7 precursor [Homo sa... 50 3e-06
gi|4504377 hemochromatosis protein isoform 1 precursor [Homo sap... 50 3e-06
gi|21040355 hemochromatosis protein isoform 10 precursor [Homo s... 50 6e-06
gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo ... 50 6e-06
gi|21040343 hemochromatosis protein isoform 4 precursor [Homo sa... 49 7e-06
gi|21040341 hemochromatosis protein isoform 3 precursor [Homo sa... 49 1e-05
gi|18641375 major histocompatibility complex, class II, DR beta ... 49 1e-05
gi|239740855 PREDICTED: similar to major histocompatibility comp... 48 2e-05
gi|239740853 PREDICTED: similar to major histocompatibility comp... 48 2e-05
gi|239748788 PREDICTED: similar to major histocompatibility comp... 48 2e-05
gi|239740863 PREDICTED: similar to major histocompatibility comp... 48 2e-05
gi|239513955 PREDICTED: similar to major histocompatibility comp... 48 2e-05
gi|99028881 V-set domain containing T cell activation inhibitor ... 48 2e-05
gi|71274107 melanoma cell adhesion molecule [Homo sapiens] 47 3e-05
gi|21040351 hemochromatosis protein isoform 8 precursor [Homo sa... 47 4e-05
gi|21040347 hemochromatosis protein isoform 6 precursor [Homo sa... 47 4e-05
gi|239758095 PREDICTED: similar to major histocompatibility comp... 47 4e-05
gi|239758092 PREDICTED: similar to HLA class II histocompatibili... 47 4e-05
>gi|157739930 TAP binding protein-like [Homo sapiens]
Length = 468
Score = 926 bits (2393), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MGTQEGWCLLLCLALSGAAETKPHPAEGQWRAVDVVLDCFLAKDGAHRGALASSEDRARA 60
MGTQEGWCLLLCLALSGAAETKPHPAEGQWRAVDVVLDCFLAKDGAHRGALASSEDRARA
Sbjct: 1 MGTQEGWCLLLCLALSGAAETKPHPAEGQWRAVDVVLDCFLAKDGAHRGALASSEDRARA 60
Query: 61 SLVLKQVPVLDDGSLEDFTDFQGGTLAQDDPPIIFEASVDLVQIPQAEALLHADCSGKEV 120
SLVLKQVPVLDDGSLEDFTDFQGGTLAQDDPPIIFEASVDLVQIPQAEALLHADCSGKEV
Sbjct: 61 SLVLKQVPVLDDGSLEDFTDFQGGTLAQDDPPIIFEASVDLVQIPQAEALLHADCSGKEV 120
Query: 121 TCEISRYFLQMTETTVKTAAWFMANMQVSGGGPSISLVMKTPRVTKNEALWHPTLNLPLS 180
TCEISRYFLQMTETTVKTAAWFMANMQVSGGGPSISLVMKTPRVTKNEALWHPTLNLPLS
Sbjct: 121 TCEISRYFLQMTETTVKTAAWFMANMQVSGGGPSISLVMKTPRVTKNEALWHPTLNLPLS 180
Query: 181 PQGTVRTAVEFQVMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYS 240
PQGTVRTAVEFQVMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYS
Sbjct: 181 PQGTVRTAVEFQVMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYS 240
Query: 241 WTAGQGQAVRKGATLEPAQLGMARDASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNI 300
WTAGQGQAVRKGATLEPAQLGMARDASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNI
Sbjct: 241 WTAGQGQAVRKGATLEPAQLGMARDASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNI 300
Query: 301 QASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVA 360
QASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVA
Sbjct: 301 QASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVA 360
Query: 361 GTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLFLLA 420
GTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLFLLA
Sbjct: 361 GTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLFLLA 420
Query: 421 LMFLGLQRRQAPTGLGLLQAERWETTSCADTQSSHLHEDRTARVSQPS 468
LMFLGLQRRQAPTGLGLLQAERWETTSCADTQSSHLHEDRTARVSQPS
Sbjct: 421 LMFLGLQRRQAPTGLGLLQAERWETTSCADTQSSHLHEDRTARVSQPS 468
>gi|27436893 tapasin isoform 1 precursor [Homo sapiens]
Length = 448
Score = 77.4 bits (189), Expect = 3e-14
Identities = 117/453 (25%), Positives = 174/453 (38%), Gaps = 67/453 (14%)
Query: 9 LLLCLALSGAAETKPHPAEGQWRAVDVVLDCFLAKDGAHRGALASSEDRARASLVLKQVP 68
LLL +AL A PA V++C+ +D + +G + +L+L+Q P
Sbjct: 6 LLLAVALGLATAVSAGPA---------VIECWFVEDASGKGLA-----KRPGALLLRQGP 51
Query: 69 VLDDGSLEDFTDFQGGT-LAQDDPPIIFEASVDLVQIPQAEALLHADCSGKEVTCEISRY 127
G D L+ DP +A+ + P+ H CE+SR+
Sbjct: 52 ----GEPPPRPDLDPELYLSVHDPAGALQAAFR--RYPRGAPAPH---------CEMSRF 96
Query: 128 FLQMTETTVKTAAWFMANMQVSGGGPSISLVMKTPRVTKNEALWHPTLNLPLSPQGTVRT 187
+ N + G + + + +P V +L P P
Sbjct: 97 VPLPASAKWASGLTPAQNCPRALDGAWLMVSISSP-VLSLSSLLRPQPEPQQEPVLITMA 155
Query: 188 AVEFQVMTQTQSLSFLLGSSASLDCGF-----------SMAPGLDLISVEWRLQHKGRGQ 236
V V+T T + LG A LD F S+APG +EWR QH G+G
Sbjct: 156 TVVLTVLTHTPAPRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGH 215
Query: 237 LVYSWTA---GQGQAVRKGATLEPAQLG------MARDASLTLPGLTIQDEGTYICQITT 287
L+ + T GQ A ++GA A + + LP + EGTY+ I
Sbjct: 216 LLLAATPGLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHL 275
Query: 288 SLYRAQQIIQLNIQASPKVRLSLANEALL------PTLICDIAGYYPL-DVVVTW-TREE 339
+ Q ++L + PKV L A A P L+C ++ +YP + V W R
Sbjct: 276 PYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGG 335
Query: 340 LGGSPAQVSGASF-SSLRQSVAGTYSISSSLTAEPGSA---GATYTCQVTHISLEEPLGA 395
GG + G + S+LR G+ S+S L P + GA Y C++ H SL P
Sbjct: 336 PGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSL--PASG 393
Query: 396 STQVVPPERRTALGVIFASS--LFLLALMFLGL 426
+ V E G S LFL A + LGL
Sbjct: 394 RSAEVTLEVAGLSGPSLEDSVGLFLSAFLLLGL 426
>gi|27436897 tapasin isoform 3 precursor [Homo sapiens]
Length = 412
Score = 73.6 bits (179), Expect = 4e-13
Identities = 105/414 (25%), Positives = 160/414 (38%), Gaps = 63/414 (15%)
Query: 9 LLLCLALSGAAETKPHPAEGQWRAVDVVLDCFLAKDGAHRGALASSEDRARASLVLKQVP 68
LLL +AL A PA V++C+ +D + +G + +L+L+Q P
Sbjct: 6 LLLAVALGLATAVSAGPA---------VIECWFVEDASGKGLA-----KRPGALLLRQGP 51
Query: 69 VLDDGSLEDFTDFQGGT-LAQDDPPIIFEASVDLVQIPQAEALLHADCSGKEVTCEISRY 127
G D L+ DP +A+ + P+ H CE+SR+
Sbjct: 52 ----GEPPPRPDLDPELYLSVHDPAGALQAAFR--RYPRGAPAPH---------CEMSRF 96
Query: 128 FLQMTETTVKTAAWFMANMQVSGGGPSISLVMKTPRVTKNEALWHPTLNLPLSPQGTVRT 187
+ N + G + + + +P V +L P P
Sbjct: 97 VPLPASAKWASGLTPAQNCPRALDGAWLMVSISSP-VLSLSSLLRPQPEPQQEPVLITMA 155
Query: 188 AVEFQVMTQTQSLSFLLGSSASLDCGF-----------SMAPGLDLISVEWRLQHKGRGQ 236
V V+T T + LG A LD F S+APG +EWR QH G+G
Sbjct: 156 TVVLTVLTHTPAPRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGH 215
Query: 237 LVYSWTA---GQGQAVRKGATLEPAQLG------MARDASLTLPGLTIQDEGTYICQITT 287
L+ + T GQ A ++GA A + + LP + EGTY+ I
Sbjct: 216 LLLAATPGLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHL 275
Query: 288 SLYRAQQIIQLNIQASPKVRLSLANEALL------PTLICDIAGYYPL-DVVVTW-TREE 339
+ Q ++L + PKV L A A P L+C ++ +YP + V W R
Sbjct: 276 PYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGG 335
Query: 340 LGGSPAQVSGASF-SSLRQSVAGTYSISSSLTAEPGSA---GATYTCQVTHISL 389
GG + G + S+LR G+ S+S L P + GA Y C++ H SL
Sbjct: 336 PGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSL 389
>gi|67188443 CD276 antigen isoform a [Homo sapiens]
Length = 534
Score = 68.2 bits (165), Expect = 2e-11
Identities = 106/398 (26%), Positives = 164/398 (41%), Gaps = 50/398 (12%)
Query: 57 RARASLVLKQVPVLDDGSLEDFT---DFQGGTLA------QDDPPIIFEASVDLVQIPQA 107
+ ASL L++V V D+GS F DF ++ P + E + DL +
Sbjct: 102 QGNASLRLQRVRVADEGSFTCFVSIRDFGSAAVSLQVAAPYSKPSMTLEPNKDL----RP 157
Query: 108 EALLHADCSGKEVTCEISRYFL--QMTETTVKTAAWFMANMQVSGGGPSISLVMKTPRVT 165
+ CS + E ++ Q T MAN Q SI V+ T
Sbjct: 158 GDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHSILRVVLGANGT 217
Query: 166 KNEALWHPTL------NLPLSPQGTVRTAVEFQVMTQTQSLSFLLGSSASLDCGFSMAPG 219
+ + +P L ++ ++PQ + AVE QV + L+G+ A+L C FS PG
Sbjct: 218 YSCLVRNPVLQQDAHSSVTITPQRSPTGAVEVQV--PEDPVVALVGTDATLRCSFSPEPG 275
Query: 220 LDLISVEWRLQHKGRGQLVYSWTAG--QGQAVRKGATLEPAQLGMARDASLTLPGLTIQD 277
L + Q QLV+S+T G QG A L P L +ASL L + + D
Sbjct: 276 FSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYANRTALFPDLLAQG-NASLRLQRVRVAD 334
Query: 278 EGTYICQITTSLYRAQQIIQLNIQA---SPKVRLSLANEALLP----TLICDIAGYYPLD 330
EG++ C ++ + + L + A P + L N+ L P T+ C YP +
Sbjct: 335 EGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMTLE-PNKDLRPGDTVTITCSSYRGYP-E 391
Query: 331 VVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGATYTCQVTHISLE 390
V W G ++G +S + G + + S L G+ G TY+C V + L+
Sbjct: 392 AEVFWQ----DGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVLGANG-TYSCLVRNPVLQ 446
Query: 391 EPLGASTQVV------PPERRTALGVIFASSLFLLALM 422
+ S + PPE AL V S+ L+AL+
Sbjct: 447 QDAHGSVTITGQPMTFPPE---ALWVTVGLSVCLIALL 481
Score = 58.2 bits (139), Expect = 2e-08
Identities = 59/213 (27%), Positives = 92/213 (43%), Gaps = 18/213 (8%)
Query: 203 LLGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYSWTAG--QGQAVRKGATLEPAQL 260
L+G+ A+L C FS PG L + Q QLV+S+ G QG A L P L
Sbjct: 41 LVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLL 100
Query: 261 GMARDASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNIQA---SPKVRLSLANEALLP 317
+ASL L + + DEG++ C ++ + + L + A P + L N+ L P
Sbjct: 101 AQG-NASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMTLE-PNKDLRP 157
Query: 318 ----TLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEP 373
T+ C YP + V W G ++G +S + G + + S L
Sbjct: 158 GDTVTITCSSYQGYP-EAEVFWQ----DGQGVPLTGNVTTSQMANEQGLFDVHSILRVVL 212
Query: 374 GSAGATYTCQVTHISLEEPLGASTQVVPPERRT 406
G+ G TY+C V + L++ +S + P T
Sbjct: 213 GANG-TYSCLVRNPVLQQDAHSSVTITPQRSPT 244
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 60.8 bits (146), Expect = 2e-09
Identities = 61/212 (28%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 193 VMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVE---WRLQHKGRGQLVYSWTAGQGQAV 249
V TQ FL G S +L C + P +++ V W + V+ T G +
Sbjct: 31 VQAPTQVPGFL-GDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSE 88
Query: 250 RKGATLEPAQLGMA-RDASLTLPGLTIQDEGTYICQITTSLYRAQQI-IQLNIQASPK-- 305
K A+LG R+ASL + GL ++DEG Y C T ++ + I L + A P+
Sbjct: 89 SKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNT 148
Query: 306 ---VRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGT 362
++ L E +P C G P +TW +LGG P + S + ++GT
Sbjct: 149 AEVQKVQLTGEP-VPMARCVSTGGRP-PAQITW-HSDLGGMP------NTSQVPGFLSGT 199
Query: 363 YSISSSLTAEPGSA--GATYTCQVTHISLEEP 392
+++S P S G TC+V H S E+P
Sbjct: 200 VTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 60.8 bits (146), Expect = 2e-09
Identities = 61/212 (28%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 193 VMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVE---WRLQHKGRGQLVYSWTAGQGQAV 249
V TQ FL G S +L C + P +++ V W + V+ T G +
Sbjct: 31 VQAPTQVPGFL-GDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSE 88
Query: 250 RKGATLEPAQLGMA-RDASLTLPGLTIQDEGTYICQITTSLYRAQQI-IQLNIQASPK-- 305
K A+LG R+ASL + GL ++DEG Y C T ++ + I L + A P+
Sbjct: 89 SKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNT 148
Query: 306 ---VRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGT 362
++ L E +P C G P +TW +LGG P + S + ++GT
Sbjct: 149 AEVQKVQLTGEP-VPMARCVSTGGRP-PAQITW-HSDLGGMP------NTSQVPGFLSGT 199
Query: 363 YSISSSLTAEPGSA--GATYTCQVTHISLEEP 392
+++S P S G TC+V H S E+P
Sbjct: 200 VTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 60.8 bits (146), Expect = 2e-09
Identities = 61/212 (28%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 193 VMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVE---WRLQHKGRGQLVYSWTAGQGQAV 249
V TQ FL G S +L C + P +++ V W + V+ T G +
Sbjct: 31 VQAPTQVPGFL-GDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSE 88
Query: 250 RKGATLEPAQLGMA-RDASLTLPGLTIQDEGTYICQITTSLYRAQQI-IQLNIQASPK-- 305
K A+LG R+ASL + GL ++DEG Y C T ++ + I L + A P+
Sbjct: 89 SKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNT 148
Query: 306 ---VRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGT 362
++ L E +P C G P +TW +LGG P + S + ++GT
Sbjct: 149 AEVQKVQLTGEP-VPMARCVSTGGRP-PAQITW-HSDLGGMP------NTSQVPGFLSGT 199
Query: 363 YSISSSLTAEPGSA--GATYTCQVTHISLEEP 392
+++S P S G TC+V H S E+P
Sbjct: 200 VTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 60.8 bits (146), Expect = 2e-09
Identities = 61/212 (28%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 193 VMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVE---WRLQHKGRGQLVYSWTAGQGQAV 249
V TQ FL G S +L C + P +++ V W + V+ T G +
Sbjct: 31 VQAPTQVPGFL-GDSVTLPC-YLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSE 88
Query: 250 RKGATLEPAQLGMA-RDASLTLPGLTIQDEGTYICQITTSLYRAQQI-IQLNIQASPK-- 305
K A+LG R+ASL + GL ++DEG Y C T ++ + I L + A P+
Sbjct: 89 SKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNT 148
Query: 306 ---VRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGT 362
++ L E +P C G P +TW +LGG P + S + ++GT
Sbjct: 149 AEVQKVQLTGEP-VPMARCVSTGGRP-PAQITW-HSDLGGMP------NTSQVPGFLSGT 199
Query: 363 YSISSSLTAEPGSA--GATYTCQVTHISLEEP 392
+++S P S G TC+V H S E+P
Sbjct: 200 VTVTSLWILVPSSQVDGKNVTCKVEHESFEKP 231
>gi|13376852 CD276 antigen isoform b [Homo sapiens]
Length = 316
Score = 59.7 bits (143), Expect = 6e-09
Identities = 67/235 (28%), Positives = 102/235 (43%), Gaps = 27/235 (11%)
Query: 203 LLGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYSWTAG--QGQAVRKGATLEPAQL 260
L+G+ A+L C FS PG L + Q QLV+S+ G QG A L P L
Sbjct: 41 LVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYANRTALFPDLL 100
Query: 261 GMARDASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNIQA---SPKVRLSLANEALLP 317
+ASL L + + DEG++ C ++ + + L + A P + L N+ L P
Sbjct: 101 AQG-NASLRLQRVRVADEGSFTCFVSIRDF-GSAAVSLQVAAPYSKPSMTLE-PNKDLRP 157
Query: 318 ----TLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEP 373
T+ C YP + V W G ++G +S + G + + S L
Sbjct: 158 GDTVTITCSSYRGYP-EAEVFWQ----DGQGVPLTGNVTTSQMANEQGLFDVHSVLRVVL 212
Query: 374 GSAGATYTCQVTHISLEEPLGASTQVV------PPERRTALGVIFASSLFLLALM 422
G+ G TY+C V + L++ S + PPE AL V S+ L+AL+
Sbjct: 213 GANG-TYSCLVRNPVLQQDAHGSVTITGQPMTFPPE---ALWVTVGLSVCLIALL 263
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 53.1 bits (126), Expect = 5e-07
Identities = 45/139 (32%), Positives = 68/139 (48%), Gaps = 21/139 (15%)
Query: 264 RDASLTLPGLTIQDEGTYICQITT-SLYRAQQIIQLNIQASPKVRLSLANEALLPTLICD 322
+DA+L L GLT++DEG Y C+ T + + L + A PK + EA T D
Sbjct: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQA----EAQKVTFSQD 176
Query: 323 IAGYYPLDVVVTWTREELGGSPAQVS-------GASFSSLRQSVAGTYSISSSLTAEPG- 374
P V + ++E G PA++S A + + ++AGT +++S T P
Sbjct: 177 -----PTTVALCISKE--GRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSG 229
Query: 375 -SAGATYTCQVTHISLEEP 392
+ G T TC+V H S EEP
Sbjct: 230 RADGVTVTCKVEHESFEEP 248
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 53.1 bits (126), Expect = 5e-07
Identities = 45/139 (32%), Positives = 68/139 (48%), Gaps = 21/139 (15%)
Query: 264 RDASLTLPGLTIQDEGTYICQITT-SLYRAQQIIQLNIQASPKVRLSLANEALLPTLICD 322
+DA+L L GLT++DEG Y C+ T + + L + A PK + EA T D
Sbjct: 121 QDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQA----EAQKVTFSQD 176
Query: 323 IAGYYPLDVVVTWTREELGGSPAQVS-------GASFSSLRQSVAGTYSISSSLTAEPG- 374
P V + ++E G PA++S A + + ++AGT +++S T P
Sbjct: 177 -----PTTVALCISKE--GRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSG 229
Query: 375 -SAGATYTCQVTHISLEEP 392
+ G T TC+V H S EEP
Sbjct: 230 RADGVTVTCKVEHESFEEP 248
>gi|21040353 hemochromatosis protein isoform 9 precursor [Homo
sapiens]
Length = 325
Score = 50.4 bits (119), Expect = 3e-06
Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Query: 298 LNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQ 357
L+ Q P V+++ + + TL C YYP ++ + W +++ P +
Sbjct: 179 LDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDK---QPMDAKEFEPKDVLP 235
Query: 358 SVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLF 417
+ GTY +L PG YTCQV H L++PL + P +GVI ++F
Sbjct: 236 NGDGTYQGWITLAVPPGEE-QRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVF 293
Query: 418 L----LALMFLGLQRRQAPTG 434
+ + ++F+ L++RQ G
Sbjct: 294 VVILFIGILFIILRKRQGSRG 314
>gi|21040349 hemochromatosis protein isoform 7 precursor [Homo
sapiens]
Length = 260
Score = 50.4 bits (119), Expect = 3e-06
Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Query: 298 LNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQ 357
L+ Q P V+++ + + TL C YYP ++ + W +++ P +
Sbjct: 114 LDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDK---QPMDAKEFEPKDVLP 170
Query: 358 SVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLF 417
+ GTY +L PG YTCQV H L++PL + P +GVI ++F
Sbjct: 171 NGDGTYQGWITLAVPPGEE-QRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVF 228
Query: 418 L----LALMFLGLQRRQAPTG 434
+ + ++F+ L++RQ G
Sbjct: 229 VVILFIGILFIILRKRQGSRG 249
>gi|4504377 hemochromatosis protein isoform 1 precursor [Homo
sapiens]
Length = 348
Score = 50.4 bits (119), Expect = 3e-06
Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 9/141 (6%)
Query: 298 LNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQ 357
L+ Q P V+++ + + TL C YYP ++ + W +++ P +
Sbjct: 202 LDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDK---QPMDAKEFEPKDVLP 258
Query: 358 SVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLF 417
+ GTY +L PG YTCQV H L++PL + P +GVI ++F
Sbjct: 259 NGDGTYQGWITLAVPPGEE-QRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVF 316
Query: 418 L----LALMFLGLQRRQAPTG 434
+ + ++F+ L++RQ G
Sbjct: 317 VVILFIGILFIILRKRQGSRG 337
>gi|21040355 hemochromatosis protein isoform 10 precursor [Homo
sapiens]
Length = 168
Score = 49.7 bits (117), Expect = 6e-06
Identities = 36/144 (25%), Positives = 66/144 (45%), Gaps = 9/144 (6%)
Query: 295 IIQLNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSS 354
++Q + P V+++ + + TL C YYP ++ + W +++ P
Sbjct: 19 VLQGRLLLPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDK---QPMDAKEFEPKD 75
Query: 355 LRQSVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFAS 414
+ + GTY +L PG YTCQV H L++PL + P +GVI
Sbjct: 76 VLPNGDGTYQGWITLAVPPGEE-QRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGI 133
Query: 415 SLFL----LALMFLGLQRRQAPTG 434
++F+ + ++F+ L++RQ G
Sbjct: 134 AVFVVILFIGILFIILRKRQGSRG 157
>gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo
sapiens]
Length = 264
Score = 49.7 bits (117), Expect = 6e-06
Identities = 56/213 (26%), Positives = 85/213 (39%), Gaps = 30/213 (14%)
Query: 193 VMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYSWTAGQGQAVRKG 252
V+TQ S S G ++ C S + + +V W Q G + ++ Q + G
Sbjct: 48 VLTQPPSASGTPGQRVTISCSGSSS-NIGSNTVNWYQQLPGTAPKLLIYSNNQRPS---G 103
Query: 253 ATLEPAQLGMARDASLTLPGLTIQDEGTYICQITTSLYRAQQI------IQLNIQASPKV 306
+ ASL + GL +DE Y C +L + PK
Sbjct: 104 VPDRFSGSKSGTSASLAISGLQSEDEADYYCAAWDDSLNGPTCWVFGGGTKLTVLGQPKA 163
Query: 307 RLSL-----------ANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSL 355
S+ AN+A TL+C I+ +YP V V W + SP + + +
Sbjct: 164 APSVTLFPPSSEELQANKA---TLVCLISDFYPGAVTVAWKADS---SPVKAGVETTTPS 217
Query: 356 RQSVAGTYSISS--SLTAEPGSAGATYTCQVTH 386
+QS Y+ SS SLT E + +Y+CQVTH
Sbjct: 218 KQS-NNKYAASSYLSLTPEQWKSHRSYSCQVTH 249
>gi|21040343 hemochromatosis protein isoform 4 precursor [Homo
sapiens]
Length = 256
Score = 49.3 bits (116), Expect = 7e-06
Identities = 53/254 (20%), Positives = 101/254 (39%), Gaps = 27/254 (10%)
Query: 185 VRTAVEFQVMTQTQSLSFLLGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYSWTAG 244
++TAV + ++ SL +L ++ D G S+ L + + + + + V T
Sbjct: 15 LQTAVLQGRLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPW 74
Query: 245 QGQAVRKGATLEPAQLGMARDASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNIQASP 304
+ L+ +Q D T+ TI + + + P
Sbjct: 75 VSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHS------------------KVPP 116
Query: 305 KVRLSLANEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYS 364
V+++ + + TL C YYP ++ + W +++ P + + GTY
Sbjct: 117 LVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDK---QPMDAKEFEPKDVLPNGDGTYQ 173
Query: 365 ISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLFL----LA 420
+L PG YTCQV H L++PL + P +GVI ++F+ +
Sbjct: 174 GWITLAVPPGEE-QRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIG 231
Query: 421 LMFLGLQRRQAPTG 434
++F+ L++RQ G
Sbjct: 232 ILFIILRKRQGSRG 245
>gi|21040341 hemochromatosis protein isoform 3 precursor [Homo
sapiens]
Length = 242
Score = 48.9 bits (115), Expect = 1e-05
Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 9/127 (7%)
Query: 312 NEALLPTLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTA 371
N + + TL C YYP ++ + W +++ P + + GTY +L
Sbjct: 110 NHSKVTTLRCRALNYYPQNITMKWLKDK---QPMDAKEFEPKDVLPNGDGTYQGWITLAV 166
Query: 372 EPGSAGATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLFL----LALMFLGLQ 427
PG YTCQV H L++PL + P +GVI ++F+ + ++F+ L+
Sbjct: 167 PPGEE-QRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGILFIILR 224
Query: 428 RRQAPTG 434
+RQ G
Sbjct: 225 KRQGSRG 231
>gi|18641375 major histocompatibility complex, class II, DR beta 5
precursor [Homo sapiens]
Length = 266
Score = 48.5 bits (114), Expect = 1e-05
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 12/142 (8%)
Query: 301 QASPKVRLSLANEALLP---TLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQ 357
+ PKV + A L L+C + G+YP + V W R S + +G + L Q
Sbjct: 123 RVEPKVTVYPARTQTLQHHNLLVCSVNGFYPGSIEVRWFRN----SQEEKAGVVSTGLIQ 178
Query: 358 SVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPL----GASTQVVPPERRTALGVIFA 413
+ T+ L P S G YTCQV H S+ PL A ++ + + +G
Sbjct: 179 NGDWTFQTLVMLETVPRS-GEVYTCQVEHPSVTSPLTVEWRAQSESAQSKMLSGVGGFVL 237
Query: 414 SSLFLLALMFLGLQRRQAPTGL 435
LFL A +F+ + ++ +GL
Sbjct: 238 GLLFLGAGLFIYFKNQKGHSGL 259
>gi|239740855 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 1 [Homo sapiens]
Length = 267
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 9/121 (7%)
Query: 319 LICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGA 378
L+C ++G+YP + V W R + +G + L Q+ T+ L P S G
Sbjct: 145 LVCSVSGFYPGSIEVRWFR----NGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRS-GE 199
Query: 379 TYTCQVTHISLEEPL----GASTQVVPPERRTALGVIFASSLFLLALMFLGLQRRQAPTG 434
YTCQV H S+ PL A ++ + + +G LFL A +F+ + ++ +G
Sbjct: 200 VYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 259
Query: 435 L 435
L
Sbjct: 260 L 260
>gi|239740853 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 3 isoform 2 [Homo sapiens]
Length = 266
Score = 48.1 bits (113), Expect = 2e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 9/121 (7%)
Query: 319 LICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGA 378
L+C ++G+YP + V W R + +G + L Q+ T+ L P S G
Sbjct: 144 LVCSVSGFYPGSIEVRWFR----NGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRS-GE 198
Query: 379 TYTCQVTHISLEEPL----GASTQVVPPERRTALGVIFASSLFLLALMFLGLQRRQAPTG 434
YTCQV H S+ PL A ++ + + +G LFL A +F+ + ++ +G
Sbjct: 199 VYTCQVEHPSVTSPLTVEWSARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 258
Query: 435 L 435
L
Sbjct: 259 L 259
>gi|239748788 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 isoform 2 [Homo sapiens]
Length = 281
Score = 47.8 bits (112), Expect = 2e-05
Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 25/184 (13%)
Query: 281 YICQITTSLYRAQQIIQLNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREEL 340
Y ++ T+L R ++ + SP +L + LL +C + +YP + V W R +
Sbjct: 115 YQLELRTTLQRR---VEPTVTISPSRTEALNHHNLL---VCSVTDFYPAQIKVRWFRND- 167
Query: 341 GGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVV 400
+ +G + L ++ T+ I L P G YTC V H SL+ P+ +
Sbjct: 168 ---QEETAGVVSTPLIRNGDWTFQILVMLEMTP-QRGDVYTCHVEHPSLQSPITVEWRAQ 223
Query: 401 PPERRTALGVIFASSLFLLALMFLGL--------QRRQAPTGLGLLQAERWETTSCADTQ 452
++ + + F+L L+FLGL Q+ + P G + RW T ++
Sbjct: 224 SESAQSKM--LSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQG----KRGRWPVTQTLCSE 277
Query: 453 SSHL 456
S L
Sbjct: 278 RSCL 281
>gi|239740863 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 47.8 bits (112), Expect = 2e-05
Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 25/184 (13%)
Query: 281 YICQITTSLYRAQQIIQLNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREEL 340
Y ++ T+L R ++ + SP +L + LL +C + +YP + V W R +
Sbjct: 115 YQLELRTTLQRR---VEPTVTISPSRTEALNHHNLL---VCSVTDFYPAQIKVRWFRND- 167
Query: 341 GGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVV 400
+ +G + L ++ T+ I L P G YTC V H SL+ P+ +
Sbjct: 168 ---QEETAGVVSTPLIRNGDWTFQILVMLEMTP-QRGDVYTCHVEHPSLQSPITVEWRAQ 223
Query: 401 PPERRTALGVIFASSLFLLALMFLGL--------QRRQAPTGLGLLQAERWETTSCADTQ 452
++ + + F+L L+FLGL Q+ + P G + RW T ++
Sbjct: 224 SESAQSKM--LSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQG----KRGRWPVTQTLCSE 277
Query: 453 SSHL 456
S L
Sbjct: 278 RSCL 281
>gi|239513955 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 47.8 bits (112), Expect = 2e-05
Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 25/184 (13%)
Query: 281 YICQITTSLYRAQQIIQLNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREEL 340
Y ++ T+L R ++ + SP +L + LL +C + +YP + V W R +
Sbjct: 115 YQLELRTTLQRR---VEPTVTISPSRTEALNHHNLL---VCSVTDFYPAQIKVRWFRND- 167
Query: 341 GGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVV 400
+ +G + L ++ T+ I L P G YTC V H SL+ P+ +
Sbjct: 168 ---QEETAGVVSTPLIRNGDWTFQILVMLEMTP-QRGDVYTCHVEHPSLQSPITVEWRAQ 223
Query: 401 PPERRTALGVIFASSLFLLALMFLGL--------QRRQAPTGLGLLQAERWETTSCADTQ 452
++ + + F+L L+FLGL Q+ + P G + RW T ++
Sbjct: 224 SESAQSKM--LSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQG----KRGRWPVTQTLCSE 277
Query: 453 SSHL 456
S L
Sbjct: 278 RSCL 281
>gi|99028881 V-set domain containing T cell activation inhibitor 1
[Homo sapiens]
Length = 282
Score = 47.8 bits (112), Expect = 2e-05
Identities = 46/186 (24%), Positives = 80/186 (43%), Gaps = 11/186 (5%)
Query: 204 LGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYSWTAGQGQAVR-----KGATLEPA 258
+G L C F L I ++W + G LV+ + G+ + +G T A
Sbjct: 48 IGEDGILSCTFEPDIKLSDIVIQWLKE--GVLGLVHEFKEGKDELSEQDEMFRGRTAVFA 105
Query: 259 QLGMARDASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNIQASPKVRLSLANEALLPT 318
+ +ASL L + + D GTY C I TS + ++ A +++ A T
Sbjct: 106 DQVIVGNASLRLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSET 165
Query: 319 LICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGA 378
L C+ ++P VV ++ + G + ++VS SF ++V T + S L +
Sbjct: 166 LRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENV--TMKVVSVLYNV--TINN 221
Query: 379 TYTCQV 384
TY+C +
Sbjct: 222 TYSCMI 227
>gi|71274107 melanoma cell adhesion molecule [Homo sapiens]
Length = 646
Score = 47.4 bits (111), Expect = 3e-05
Identities = 52/184 (28%), Positives = 82/184 (44%), Gaps = 27/184 (14%)
Query: 204 LGSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYSWTAGQGQAVRKGATLEPAQLGMA 263
+GS+A L CG S + G +L V+W HK + L++ GQGQ+ + E
Sbjct: 40 VGSTALLKCGLSQSQG-NLSHVDWFSVHKEKRTLIFRVRQGQGQS--EPGEYEQRLSLQD 96
Query: 264 RDASLTLPGLTIQDEGTYICQ----------ITTSLYRAQQIIQLNIQASPKVRLSLANE 313
R A+L L +T QDE ++CQ I +Y+A + + NIQ +P L +
Sbjct: 97 RGATLALTQVTPQDERIFLCQGKRPRSQEYRIQLRVYKAPE--EPNIQVNP---LGIPVN 151
Query: 314 ALLPTLICDIAGY--YPLDVVVTWTREELGGSPAQVSGASF---SSLRQSVAGTYSISSS 368
+ P + G YP+ V+ W + G P + SS +G Y++ S
Sbjct: 152 SKEPEEVATCVGRNGYPIPQVI-WYK---NGRPLKEEKNRVHIQSSQTVESSGLYTLQSI 207
Query: 369 LTAE 372
L A+
Sbjct: 208 LKAQ 211
>gi|21040351 hemochromatosis protein isoform 8 precursor [Homo
sapiens]
Length = 246
Score = 47.0 bits (110), Expect = 4e-05
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 318 TLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAG 377
TL C YYP ++ + W +++ P + + GTY +L PG
Sbjct: 120 TLRCRALNYYPQNITMKWLKDK---QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEE- 175
Query: 378 ATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLFL----LALMFLGLQRRQAPT 433
YTCQV H L++PL + P +GVI ++F+ + ++F+ L++RQ
Sbjct: 176 QRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSR 234
Query: 434 G 434
G
Sbjct: 235 G 235
>gi|21040347 hemochromatosis protein isoform 6 precursor [Homo
sapiens]
Length = 334
Score = 47.0 bits (110), Expect = 4e-05
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 9/121 (7%)
Query: 318 TLICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAG 377
TL C YYP ++ + W +++ P + + GTY +L PG
Sbjct: 208 TLRCRALNYYPQNITMKWLKDK---QPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEE- 263
Query: 378 ATYTCQVTHISLEEPLGASTQVVPPERRTALGVIFASSLFL----LALMFLGLQRRQAPT 433
YTCQV H L++PL + P +GVI ++F+ + ++F+ L++RQ
Sbjct: 264 QRYTCQVEHPGLDQPLIVIWE-PSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSR 322
Query: 434 G 434
G
Sbjct: 323 G 323
>gi|239758095 PREDICTED: similar to major histocompatibility
complex, class II, DR beta 5 [Homo sapiens]
Length = 281
Score = 47.0 bits (110), Expect = 4e-05
Identities = 45/184 (24%), Positives = 77/184 (41%), Gaps = 25/184 (13%)
Query: 281 YICQITTSLYRAQQIIQLNIQASPKVRLSLANEALLPTLICDIAGYYPLDVVVTWTREEL 340
Y ++ T+L R ++ + SP +L + LL +C + +YP + V W R
Sbjct: 115 YQLELRTTLQRR---VEPTVTISPSRTEALNHHNLL---VCSVTDFYPAQIKVRWFR--- 165
Query: 341 GGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGATYTCQVTHISLEEPLGASTQVV 400
+ +G + L ++ T+ I L P G YTC V H SL+ P+ +
Sbjct: 166 -NGQEETAGVVSTPLIRNGDWTFQILVMLEMTP-QRGDVYTCHVEHPSLQSPITVEWRAQ 223
Query: 401 PPERRTALGVIFASSLFLLALMFLGL--------QRRQAPTGLGLLQAERWETTSCADTQ 452
++ + + F+L L+FLGL Q+ + P G + RW T ++
Sbjct: 224 SESAQSKM--LSGIGGFVLGLIFLGLGLIIHHRSQKGEEPQG----KRGRWPVTQTLCSE 277
Query: 453 SSHL 456
S L
Sbjct: 278 RSCL 281
>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
antigen, DRB1-7 beta chain [Homo sapiens]
Length = 253
Score = 47.0 bits (110), Expect = 4e-05
Identities = 34/121 (28%), Positives = 56/121 (46%), Gaps = 9/121 (7%)
Query: 319 LICDIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGA 378
L+C ++G+YP + V W R + +G + L Q+ T+ L P S G
Sbjct: 131 LVCSVSGFYPGSIEVRWFR----NGQEEKAGVVSTGLIQNGDWTFQTLVMLETVPRS-GE 185
Query: 379 TYTCQVTHISLEEPL----GASTQVVPPERRTALGVIFASSLFLLALMFLGLQRRQAPTG 434
YTCQV H S+ PL A ++ + + +G LFL A +F+ + ++ +G
Sbjct: 186 VYTCQVEHPSVMSPLTVEWRARSESAQSKMLSGVGGFVLGLLFLGAGLFIYFRNQKGHSG 245
Query: 435 L 435
L
Sbjct: 246 L 246
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.131 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,811,758
Number of Sequences: 37866
Number of extensions: 760018
Number of successful extensions: 2647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 216
Number of HSP's that attempted gapping in prelim test: 2211
Number of HSP's gapped (non-prelim): 565
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.