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Search of human proteins with 157694524
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157694524 plexin D1 [Homo sapiens]
(1925 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157694524 plexin D1 [Homo sapiens] 3890 0.0
gi|253795481 plexin B3 isoform 2 [Homo sapiens] 967 0.0
gi|29336063 plexin B3 isoform 1 [Homo sapiens] 962 0.0
gi|149363636 plexin B2 [Homo sapiens] 929 0.0
gi|113722116 plexin A2 [Homo sapiens] 889 0.0
gi|157738645 plexin A4 isoform 1 [Homo sapiens] 887 0.0
gi|49355818 plexin A1 [Homo sapiens] 861 0.0
gi|59710104 plexin A3 [Homo sapiens] 860 0.0
gi|194272180 plexin B1 [Homo sapiens] 759 0.0
gi|40254442 plexin B1 [Homo sapiens] 759 0.0
gi|5032223 plexin C1 [Homo sapiens] 539 e-152
gi|153946393 macrophage stimulating 1 receptor precursor [Homo s... 99 4e-20
gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens] 99 5e-20
gi|157738647 plexin A4 isoform 3 [Homo sapiens] 88 7e-17
gi|157738643 plexin A4 isoform 2 [Homo sapiens] 88 9e-17
gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens] 87 1e-16
gi|126116589 fibrocystin L [Homo sapiens] 66 4e-10
gi|39777610 semaphorin 4B precursor [Homo sapiens] 61 1e-08
gi|39777608 semaphorin 4B precursor [Homo sapiens] 61 1e-08
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 57 2e-07
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 52 4e-06
gi|126131104 fibrocystin isoform 2 [Homo sapiens] 52 7e-06
gi|126131102 fibrocystin isoform 1 [Homo sapiens] 52 7e-06
gi|147904700 semaphorin 5A [Homo sapiens] 50 2e-05
gi|157388902 semaphorin 4C [Homo sapiens] 50 2e-05
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 50 3e-05
gi|19718780 semaphorin 6B precursor [Homo sapiens] 48 8e-05
gi|5454048 semaphorin 3C [Homo sapiens] 45 5e-04
gi|6912650 semaphorin 3E [Homo sapiens] 45 7e-04
gi|21361914 semaphorin B [Homo sapiens] 45 7e-04
>gi|157694524 plexin D1 [Homo sapiens]
Length = 1925
Score = 3890 bits (10088), Expect = 0.0
Identities = 1925/1925 (100%), Positives = 1925/1925 (100%)
Query: 1 MAPRAAGGAPLSARAAAASPPPFQTPPRCPVPLLLLLLLGAARAGALEIQRRFPSPTPTN 60
MAPRAAGGAPLSARAAAASPPPFQTPPRCPVPLLLLLLLGAARAGALEIQRRFPSPTPTN
Sbjct: 1 MAPRAAGGAPLSARAAAASPPPFQTPPRCPVPLLLLLLLGAARAGALEIQRRFPSPTPTN 60
Query: 61 NFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRL 120
NFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRL
Sbjct: 61 NFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRL 120
Query: 121 TDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSML 180
TDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSML
Sbjct: 121 TDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSML 180
Query: 181 NVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAI 240
NVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAI
Sbjct: 181 NVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAI 240
Query: 241 RSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLA 300
RSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLA
Sbjct: 241 RSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLA 300
Query: 301 LNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLYSRLVS 360
LNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLYSRLVS
Sbjct: 301 LNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLYSRLVS 360
Query: 361 VFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVVAVLD 420
VFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVVAVLD
Sbjct: 361 VFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVVAVLD 420
Query: 421 SVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGLTSVAVASVN 480
SVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGLTSVAVASVN
Sbjct: 421 SVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGLTSVAVASVN 480
Query: 481 NYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQ 540
NYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQ
Sbjct: 481 NYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQ 540
Query: 541 MARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRC 600
MARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRC
Sbjct: 541 MARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRC 600
Query: 601 PAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAY 660
PAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAY
Sbjct: 601 PAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAY 660
Query: 661 CNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSA 720
CNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSA
Sbjct: 661 CNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSA 720
Query: 721 QWPCFWCSQQHSCVSNQSRCEASPNPTSPQDCPRTLLSPLAPVPTGGSQNILVPLANTAF 780
QWPCFWCSQQHSCVSNQSRCEASPNPTSPQDCPRTLLSPLAPVPTGGSQNILVPLANTAF
Sbjct: 721 QWPCFWCSQQHSCVSNQSRCEASPNPTSPQDCPRTLLSPLAPVPTGGSQNILVPLANTAF 780
Query: 781 FQGAALECSFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPE 840
FQGAALECSFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPE
Sbjct: 781 FQGAALECSFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPE 840
Query: 841 PMTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDGCRLRGPLQPMAGTCPAPEIRAIEPLS 900
PMTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDGCRLRGPLQPMAGTCPAPEIRAIEPLS
Sbjct: 841 PMTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDGCRLRGPLQPMAGTCPAPEIRAIEPLS 900
Query: 901 GPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSG 960
GPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSG
Sbjct: 901 GPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSG 960
Query: 961 VVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTD 1020
VVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTD
Sbjct: 961 VVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTD 1020
Query: 1021 PCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSP 1080
PCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSP
Sbjct: 1021 PCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSP 1080
Query: 1081 VSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFF 1140
VSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFF
Sbjct: 1081 VSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFF 1140
Query: 1141 INGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIH 1200
INGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIH
Sbjct: 1141 INGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIH 1200
Query: 1201 KEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTI 1260
KEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTI
Sbjct: 1201 KEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTI 1260
Query: 1261 ATLQLGGSETAIIVSIVICSVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIRE 1320
ATLQLGGSETAIIVSIVICSVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIRE
Sbjct: 1261 ATLQLGGSETAIIVSIVICSVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIRE 1320
Query: 1321 EIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNS 1380
EIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNS
Sbjct: 1321 EIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNS 1380
Query: 1381 QGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRD 1440
QGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRD
Sbjct: 1381 QGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRD 1440
Query: 1441 RCSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSI 1500
RCSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSI
Sbjct: 1441 RCSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSI 1500
Query: 1501 CMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNV 1560
CMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNV
Sbjct: 1501 CMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNV 1560
Query: 1561 SFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYIL 1620
SFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYIL
Sbjct: 1561 SFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYIL 1620
Query: 1621 RDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGRVKDLDTEKYFHLVLPT 1680
RDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGRVKDLDTEKYFHLVLPT
Sbjct: 1621 RDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGRVKDLDTEKYFHLVLPT 1680
Query: 1681 DELAEPKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYF 1740
DELAEPKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYF
Sbjct: 1681 DELAEPKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYF 1740
Query: 1741 FDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQ 1800
FDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQ
Sbjct: 1741 FDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQ 1800
Query: 1801 AFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEE 1860
AFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEE
Sbjct: 1801 AFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEE 1860
Query: 1861 SRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNIYE 1920
SRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNIYE
Sbjct: 1861 SRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNIYE 1920
Query: 1921 CYSEA 1925
CYSEA
Sbjct: 1921 CYSEA 1925
>gi|253795481 plexin B3 isoform 2 [Homo sapiens]
Length = 1932
Score = 967 bits (2500), Expect = 0.0
Identities = 704/2038 (34%), Positives = 1002/2038 (49%), Gaps = 242/2038 (11%)
Query: 1 MAPRAAGGAPLSARAAAASPPPFQTPPRC----PVPLLLLLLLGAARAGALEIQRRFPSP 56
++PR G P R S P P P L LLLLL + L RF +P
Sbjct: 14 LSPRLPGSFPQLRRVPPCSRPWLPKAPVMARWPPFGLCLLLLLLSPPPLPLTGAHRFSAP 73
Query: 57 TPT-NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCE 115
T N+ AL GT+Y+ AVNRL+QLS L LEA A GPV DSP C P A C
Sbjct: 74 NTTLNHLALAPGRGTLYVGAVNRLFQLS-PELQLEAVAVTGPVIDSPDC-VPFRDPAECP 131
Query: 116 HPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTV 175
+ LTDN N++L + +V CG + QG C+ RR G+++ V + A P + V
Sbjct: 132 QAQ-LTDNANQLLLVSSRAQELVACGQVRQGVCETRRLGDVAEVLYQ---AEDPGDGQFV 187
Query: 176 FPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENT 235
AAN P +TVGLV+P G LLV G S+
Sbjct: 188 -------AANTPGVATVGLVVPLP---GRDLLLVARGLAGKLSA--------------GV 223
Query: 236 PEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQS 295
P +AIR L S + + ++ G + +V AF A+S
Sbjct: 224 PPLAIRQLAGSQPF----------SSEGLGRLVVGDFSDYNNSYVGAFAD-------ARS 266
Query: 296 YAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLY 355
++ ARA +++ RS +AR+CL GD SY+++ L C G
Sbjct: 267 AYFVFRRRGARA---QAEYRSYVARVCL-----GDTNLY--SYVEVPLACQG-------Q 309
Query: 356 SRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDV 415
+ + F A L VF + R AALCAF ++ A++ AR C+
Sbjct: 310 GLIQAAFLAPGTLLGVF-----AAGPRGTQAALCAFPMVELGASMEQARRLCYTAGGRGP 364
Query: 416 VAVLDSVVQ-GTGPACERKLNIQLQ-PEQLDCGAAHLQHPLSILQPLKATPVFR-APGLT 472
++ V+ G C + + L PE CG H P++ QPL+ P+ + ++
Sbjct: 365 SGAEEATVEYGVTSRC---VTLPLDSPESYPCGDEHTPSPIAGRQPLEVQPLLKLGQPVS 421
Query: 473 SVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGY 532
+VA + + FLG G+L K+ L+ S V G + + D + S +
Sbjct: 422 AVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQVYHSQQVGPPGSAISPDLLLDSSGS-H 480
Query: 533 LYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTS 592
LY++T+HQ+ R+ VAAC C C+ A D CGWC L+ RCT + C + Q + W
Sbjct: 481 LYVLTAHQVDRIPVAACPQFPDCASCLQAQDPLCGWCVLQGRCTRKGQCGRAGQLNQWLW 540
Query: 593 ASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGME-MACDYGNNIRTVARVPG 651
+ E S C + L RQE + L + LP L E C +G+ ++A V G
Sbjct: 541 SYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVP-RLPILDADEYFHCAFGD-YDSLAHVEG 598
Query: 652 PAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPH 711
P C P+DQ P PP DHVTV +++ + NF+ YDCS +
Sbjct: 599 PHVA-----CVTPPQDQVPLNPPGTDHVTVPLALMFEDVTVAATNFSFYDCSAVQALEAA 653
Query: 712 TACTSCLSAQWPCFWCSQQHSCVSNQ----------SRCEASPNPTSPQDCPRT--LLSP 759
C +C+ + W C WC Q CV + S E P CP+ L P
Sbjct: 654 APCRACVGSIWRCHWCPQSSHCVYGEHCPEGERTIYSAQEVDIQVRGPGACPQVEGLAGP 713
Query: 760 LAPVPTGGSQNILVPLANTAFFQG--AALECSF-------GLEEIFEAVWVNESVVRCDQ 810
VP G ++ + + N F+G A+ C GL E + ++ C
Sbjct: 714 HL-VPVGWESHLALRVRNLQHFRGLPASFHCWLELPGELRGLPATLEETAGDSGLIHCQA 772
Query: 811 VVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQC-LGREDLGHLC 869
+ + + P+ + + A+ LD+ + V++Y+CAMG PDCS C LG C
Sbjct: 773 HQFYPSMSQRELPVPIYVTQGEAQRLDNTHALYVILYDCAMGHPDCSHCQAANRSLG--C 830
Query: 870 MW-SDG---CRLRGPLQPMAGT---CPAPEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSD 922
+W +DG CR GPL P CPAP I A+EPL+GP +GG LTI G NLGR +D
Sbjct: 831 LWCADGQPACRY-GPLCPPGAVELLCPAPSIDAVEPLTGPPEGGLALTILGSNLGRAFAD 889
Query: 923 VAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKE--GKSRDRFSYVL 980
V + V + C P P Y S IVCVT PAP +G V V + G S F+Y
Sbjct: 890 VQYAVSVASRPCNPEPSLYRTSARIVCVTSPAPNGTTGPVRVAIKSQPPGISSQHFTYQD 949
Query: 981 PLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRT-DTSIACTMPEG 1039
P++ SL P GP+AGGT++TI G L G V PC L +I C
Sbjct: 950 PVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTSAFVGG-QPCPILEPVCPEAIVCRTRPQ 1008
Query: 1040 ALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQN 1099
A P V V F F Y NP + A P S GGR I V G +VQ
Sbjct: 1009 AAPGEAAVLVVFGHAQRTLLASPFRYTANPQLVAAEPSASFRGGGRLIRVRGTGLDVVQR 1068
Query: 1100 VSMAV-----------HHIGREP---------------------------TLCKVLNSTL 1121
++V ++P T+C V +S+L
Sbjct: 1069 PLLSVWLEADAEVQASRAQPQDPQPRRSCGAPAADPQACIQLGGGLLQCSTVCSVNSSSL 1128
Query: 1122 ITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTA 1181
+ C SP A FF D V V D A G F Y PNP+ +
Sbjct: 1129 LLCRSPAVPDRAHPQRVFFT-----LDNVQV-----DFASASGGQGFL--YQPNPRLAPL 1176
Query: 1182 KREKWIKHHPGEP-LTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCS--VNE 1238
RE + + +P L + E +LG+ E RV IG+ C ++ ++ ++C +
Sbjct: 1177 SREGPARPYRLKPGHVLDVEGEGLNLGISKEEVRVHIGRGECLVKTLTRTHLYCEPPAHA 1236
Query: 1239 SLGAAVGQLP-ITIQVGNFNQTIATLQ------LGGSETAIIVSIVICSVLLLLSVVAL- 1290
A LP +Q+GN + +Q L + + + +L+ +V+ L
Sbjct: 1237 PQPANGSGLPQFVVQMGNVQLALGPVQYEAEPPLSAFPVEAQAGVGMGAAVLIAAVLLLT 1296
Query: 1291 FVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLE 1350
++ KS++A R +QK L+Q+E +E+ + ++ RK F +L T+MTDL+ +L S GIPFL+
Sbjct: 1297 LMYRHKSKQALRDYQKVLVQLESLETGVGDQCRKEFTDLMTEMTDLSSDLEGS-GIPFLD 1355
Query: 1351 YKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGI 1410
Y+ + R FFP G Q GE + + +G+
Sbjct: 1356 YRTYAERAFFP------------------GHGGCPLQPKPEGPGE----DGHCATVRQGL 1393
Query: 1411 SLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDL 1470
+ S+LLN+K FL+ +H LE+Q F+ RDRC +ASLL++ALHGKLEY T IM+ LL DL
Sbjct: 1394 TQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHGKLEYLTDIMRTLLGDL 1453
Query: 1471 IDASAAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSI 1530
+NPKLMLRRTE++VEK+LTNW+SIC+Y+ LRE GEP ++L AI+ Q++KG +
Sbjct: 1454 AAHYVHRNPKLMLRRTETMVEKLLTNWLSICLYAFLREVAGEPLYMLFRAIQYQVDKGPV 1513
Query: 1531 DAITGKARYTLNEEWLLRENIEAKPRNLNVSF-QGCG-------MDSLSVRAMDTDTLTQ 1582
DA+TGKA+ TLN+ LLRE++E +P L V G G M + R +DTDT+TQ
Sbjct: 1514 DAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVGPGAGGAAGSSEMQRVPARVLDTDTITQ 1573
Query: 1583 VKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLAHY 1642
VKEK+L+ K P+SQ P +DLEW + L D D TSV ++ K+LNTL HY
Sbjct: 1574 VKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHY 1633
Query: 1643 KIPEGASLAMSLIDKKDNTLGR-----------VKDLDTEK-----YFHLVLPTDELAEP 1686
K+P+GA++ + + +T+ + + L+ + +HLV T+E
Sbjct: 1634 KVPDGATVGLVPQLHRGSTISQSLAQRCPLGENIPTLEDGEEGGVCLWHLVKATEEPEGA 1693
Query: 1687 KKS-----HRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKP-PLAVKYF 1740
K R+ R K +PEIYLTRLLS KGTLQKF+DD F+AILS+ ++P P+AVKY
Sbjct: 1694 KVRCSSLREREPARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSV--NRPIPIAVKYL 1751
Query: 1741 FDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQ 1800
FD L+E AEK GI DP TLHIWKTNSL LRFWVN LKNPQ +FD+ +D++DA L+VIAQ
Sbjct: 1752 FDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWVNALKNPQLIFDVRVSDNVDAILAVIAQ 1811
Query: 1801 AFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEE 1860
FID+C+ S+ ++G+DSP NKLLYA+EIP Y+++V+RYY I+ +P S QEMN+ LAE
Sbjct: 1812 TFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQMVERYYADIRQSSPASYQEMNSALAEL 1871
Query: 1861 SRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNI 1918
S Y + + A+ E+Y + RY QI++ALE +P ++ QL + +QV AL+E+ +
Sbjct: 1872 SGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVGQKLQLACRLQQVAALVENKV 1929
>gi|29336063 plexin B3 isoform 1 [Homo sapiens]
Length = 1909
Score = 962 bits (2488), Expect = 0.0
Identities = 696/2005 (34%), Positives = 992/2005 (49%), Gaps = 238/2005 (11%)
Query: 30 PVPLLLLLLLGAARAGALEIQRRFPSPTPT-NNFALDGAAGTVYLAAVNRLYQLSGANLS 88
P L LLLLL + L RF +P T N+ AL GT+Y+ AVNRL+QLS L
Sbjct: 24 PFGLCLLLLLLSPPPLPLTGAHRFSAPNTTLNHLALAPGRGTLYVGAVNRLFQLS-PELQ 82
Query: 89 LEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFC 148
LEA A GPV DSP C P A C + LTDN N++L + +V CG + QG C
Sbjct: 83 LEAVAVTGPVIDSPDC-VPFRDPAECPQAQ-LTDNANQLLLVSSRAQELVACGQVRQGVC 140
Query: 149 QLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLL 208
+ RR G+++ V + A P + V AAN P +TVGLV+P G LL
Sbjct: 141 ETRRLGDVAEVLYQ---AEDPGDGQFV-------AANTPGVATVGLVVPLP---GRDLLL 187
Query: 209 VGATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIK 268
V G S+ P +AIR L S + + ++
Sbjct: 188 VARGLAGKLSA--------------GVPPLAIRQLAGSQPF----------SSEGLGRLV 223
Query: 269 QGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAG 328
G + +V AF A+S ++ ARA +++ RS +AR+CL
Sbjct: 224 VGDFSDYNNSYVGAFAD-------ARSAYFVFRRRGARA---QAEYRSYVARVCL----- 268
Query: 329 GDAKKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAAL 388
GD SY+++ L C G + + F A L VF + R AAL
Sbjct: 269 GDTNLY--SYVEVPLACQG-------QGLIQAAFLAPGTLLGVF-----AAGPRGTQAAL 314
Query: 389 CAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQ-GTGPACERKLNIQLQ-PEQLDCG 446
CAF ++ A++ AR C+ ++ V+ G C + + L PE CG
Sbjct: 315 CAFPMVELGASMEQARRLCYTAGGRGPSGAEEATVEYGVTSRC---VTLPLDSPESYPCG 371
Query: 447 AAHLQHPLSILQPLKATPVFR-APGLTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQV 505
H P++ QPL+ P+ + +++VA + + FLG G+L K+ L+ S
Sbjct: 372 DEHTPSPIAGRQPLEVQPLLKLGQPVSAVAALQADGHMIAFLGDTQGQLYKVFLHGSQGQ 431
Query: 506 VSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAY 565
V G + + D + S +LY++T+HQ+ R+ VAAC C C+ A D
Sbjct: 432 VYHSQQVGPPGSAISPDLLLDSSGS-HLYVLTAHQVDRIPVAACPQFPDCASCLQAQDPL 490
Query: 566 CGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISG 625
CGWC L+ RCT + C + Q + W + E S C + L RQE + L +
Sbjct: 491 CGWCVLQGRCTRKGQCGRAGQLNQWLWSYEEDSHCLHIQSLLPGHHPRQEQGQVTLSVP- 549
Query: 626 SLPSLSGME-MACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMS 684
LP L E C +G+ ++A V GP C P+DQ P PP DHVTV ++
Sbjct: 550 RLPILDADEYFHCAFGD-YDSLAHVEGPHVA-----CVTPPQDQVPLNPPGTDHVTVPLA 603
Query: 685 VRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQ------- 737
+ + NF+ YDCS + C +C+ + W C WC Q CV +
Sbjct: 604 LMFEDVTVAATNFSFYDCSAVQALEAAAPCRACVGSIWRCHWCPQSSHCVYGEHCPEGER 663
Query: 738 ---SRCEASPNPTSPQDCPRT--LLSPLAPVPTGGSQNILVPLANTAFFQG--AALECSF 790
S E P CP+ L P VP G ++ + + N F+G A+ C
Sbjct: 664 TIYSAQEVDIQVRGPGACPQVEGLAGPHL-VPVGWESHLALRVRNLQHFRGLPASFHCWL 722
Query: 791 -------GLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMT 843
GL E + ++ C + + + P+ + + A+ LD+ +
Sbjct: 723 ELPGELRGLPATLEETAGDSGLIHCQAHQFYPSMSQRELPVPIYVTQGEAQRLDNTHALY 782
Query: 844 VMVYNCAMGSPDCSQC-LGREDLGHLCMW-SDG---CRLRGPLQPMAGT---CPAPEIRA 895
V++Y+CAMG PDCS C LG C+W +DG CR GPL P CPAP I A
Sbjct: 783 VILYDCAMGHPDCSHCQAANRSLG--CLWCADGQPACRY-GPLCPPGAVELLCPAPSIDA 839
Query: 896 IEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAP 955
+EPL+GP +GG LTI G NLGR +DV + V + C P P Y S IVCVT PAP
Sbjct: 840 VEPLTGPPEGGLALTILGSNLGRAFADVQYAVSVASRPCNPEPSLYRTSARIVCVTSPAP 899
Query: 956 GPLSGVVTVNASKE--GKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQ 1013
+G V V + G S F+Y P++ SL P GP+AGGT++TI G L G
Sbjct: 900 NGTTGPVRVAIKSQPPGISSQHFTYQDPVLLSLSPRWGPQAGGTQLTIRGQHLQTGGNTS 959
Query: 1014 VLVNDTDPCTELMRT-DTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVIT 1072
V PC L +I C A P V V F F Y NP +
Sbjct: 960 AFVGG-QPCPILEPVCPEAIVCRTRPQAAPGEAAVLVVFGHAQRTLLASPFRYTANPQLV 1018
Query: 1073 AISPRRSPVSGGRTITVAGERFHMVQNVSMAV-----------HHIGREP---------- 1111
A P S GGR I V G +VQ ++V ++P
Sbjct: 1019 AAEPSASFRGGGRLIRVRGTGLDVVQRPLLSVWLEADAEVQASRAQPQDPQPRRSCGAPA 1078
Query: 1112 -----------------TLCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAE 1154
T+C V +S+L+ C SP A FF D V V
Sbjct: 1079 ADPQACIQLGGGLLQCSTVCSVNSSSLLLCRSPAVPDRAHPQRVFFT-----LDNVQV-- 1131
Query: 1155 ELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEP-LTLVIHKEQDSLGLQSHEY 1213
D A G F Y PNP+ + RE + + +P L + E +LG+ E
Sbjct: 1132 ---DFASASGGQGFL--YQPNPRLAPLSREGPARPYRLKPGHVLDVEGEGLNLGISKEEV 1186
Query: 1214 RVKIGQVSCDIQIVSDRIIHCS--VNESLGAAVGQLP-ITIQVGNFNQTIATLQ------ 1264
RV IG+ C ++ ++ ++C + A LP +Q+GN + +Q
Sbjct: 1187 RVHIGRGECLVKTLTRTHLYCEPPAHAPQPANGSGLPQFVVQMGNVQLALGPVQYEAEPP 1246
Query: 1265 LGGSETAIIVSIVICSVLLLLSVVAL-FVFCTKSRRAERYWQKTLLQMEEMESQIREEIR 1323
L + + + +L+ +V+ L ++ KS++A R +QK L+Q+E +E+ + ++ R
Sbjct: 1247 LSAFPVEAQAGVGMGAAVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLESLETGVGDQCR 1306
Query: 1324 KGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGS 1383
K F +L T+MTDL+ +L S GIPFL+Y+ + R FFP G
Sbjct: 1307 KEFTDLMTEMTDLSSDLEGS-GIPFLDYRTYAERAFFP------------------GHGG 1347
Query: 1384 SQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCS 1443
Q GE + + +G++ S+LLN+K FL+ +H LE+Q F+ RDRC
Sbjct: 1348 CPLQPKPEGPGE----DGHCATVRQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCH 1403
Query: 1444 LASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMY 1503
+ASLL++ALHGKLEY T IM+ LL DL +NPKLMLRRTE++VEK+LTNW+SIC+Y
Sbjct: 1404 VASLLSLALHGKLEYLTDIMRTLLGDLAAHYVHRNPKLMLRRTETMVEKLLTNWLSICLY 1463
Query: 1504 SCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSF- 1562
+ LRE GEP ++L AI+ Q++KG +DA+TGKA+ TLN+ LLRE++E +P L V
Sbjct: 1464 AFLREVAGEPLYMLFRAIQYQVDKGPVDAVTGKAKRTLNDSRLLREDVEFQPLTLMVLVG 1523
Query: 1563 QGCG-------MDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASST 1615
G G M + R +DTDT+TQVKEK+L+ K P+SQ P +DLEW +
Sbjct: 1524 PGAGGAAGSSEMQRVPARVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHALDLEWRSGLA 1583
Query: 1616 QSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGR----------- 1664
L D D TSV ++ K+LNTL HYK+P+GA++ + + +T+ +
Sbjct: 1584 GHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVGLVPQLHRGSTISQSLAQRCPLGEN 1643
Query: 1665 VKDLDTEK-----YFHLVLPTDELAEPKKS-----HRQSHRKKVLPEIYLTRLLSTKGTL 1714
+ L+ + +HLV T+E K R+ R K +PEIYLTRLLS KGTL
Sbjct: 1644 IPTLEDGEEGGVCLWHLVKATEEPEGAKVRCSSLREREPARAKAIPEIYLTRLLSMKGTL 1703
Query: 1715 QKFLDDLFKAILSIREDKP-PLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWV 1773
QKF+DD F+AILS+ ++P P+AVKY FD L+E AEK GI DP TLHIWKTNSL LRFWV
Sbjct: 1704 QKFVDDTFQAILSV--NRPIPIAVKYLFDLLDELAEKHGIEDPGTLHIWKTNSLLLRFWV 1761
Query: 1774 NILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRK 1833
N LKNPQ +FD+ +D++DA L+VIAQ FID+C+ S+ ++G+DSP NKLLYA+EIP Y++
Sbjct: 1762 NALKNPQLIFDVRVSDNVDAILAVIAQTFIDSCTTSEHKVGRDSPVNKLLYAREIPRYKQ 1821
Query: 1834 IVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALE 1893
+V+RYY I+ +P S QEMN+ LAE S Y + + A+ E+Y + RY QI++ALE
Sbjct: 1822 MVERYYADIRQSSPASYQEMNSALAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALE 1881
Query: 1894 ANPTARRTQLQHKFEQVVALMEDNI 1918
+P ++ QL + +QV AL+E+ +
Sbjct: 1882 EDPVGQKLQLACRLQQVAALVENKV 1906
>gi|149363636 plexin B2 [Homo sapiens]
Length = 1838
Score = 929 bits (2401), Expect = 0.0
Identities = 666/1952 (34%), Positives = 988/1952 (50%), Gaps = 187/1952 (9%)
Query: 33 LLLLLLLGAARAGALEIQRR---FPSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSL 89
L L LLG AGA R+ F S N+ A+D A+G VYL AVN LYQL A L L
Sbjct: 5 LWALTLLGLLGAGASLRPRKLDFFRSEKELNHLAVDEASGVVYLGAVNALYQLD-AKLQL 63
Query: 90 EAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQ 149
E + A GP D+ C P + + C H +TDN N++L LDP + +V CGS+++G C
Sbjct: 64 EQQVATGPALDNKKC-TPPIEASQC-HEAEMTDNVNQLLLLDPPRKRLVECGSLFKGICA 121
Query: 150 LRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLV 209
LR NIS + + VA+N +TVGLV + G GG R+L
Sbjct: 122 LRALSNISLRLFYEDGSGEKSF----------VASNDEGVATVGLV--SSTGPGGDRVL- 168
Query: 210 GATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQ 269
+ G G+ +N ++ R LD R D + F + + K
Sbjct: 169 ---FVGKGNG-----------PHDNGIIVSTRLLD-RTDSREAFEAYTDHAT-----YKA 208
Query: 270 GAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGG 329
G + FV+AF D P Y + N + + ++ R+LLAR+C
Sbjct: 209 GYLSTNTQQFVAAF---EDGP-----YVFFVFNQQDK---HPARNRTLLARMCREDPN-- 255
Query: 330 DAKKLTESYIQLGLQCAG----GAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAP 385
SY+++ LQC A G + V+ + L+AVF R S A
Sbjct: 256 -----YYSYLEMDLQCRDPDIHAAAFGTCLAASVAAPGSGRVLYAVFSRDSRSSGGPGA- 309
Query: 386 AALCAFRFADVRAAIRAARTACFV--EPAPDVVAVL---DSVVQGTGPACERKLNIQLQP 440
LC F V A + A R AC+ A D+ D G P +
Sbjct: 310 -GLCLFPLDKVHAKMEANRNACYTGTREARDIFYKPFHGDIQCGGHAPGSSKSF------ 362
Query: 441 EQLDCGAAHLQHPLSILQPLKATPVFRAPGL--TSVAVASVNNYTAVFLGTVNGRLLKIN 498
CG+ HL +PL L+ T V + GL T+V VA+ NN+T FLGT +GR+LK+
Sbjct: 363 ---PCGSEHLPYPLGSRDGLRGTAVLQRGGLNLTAVTVAAENNHTVAFLGTSDGRILKVY 419
Query: 499 LNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDC 558
L + V + V + D G LY MT ++ R+ V C + TC C
Sbjct: 420 LTPDGTSSEYDSILVEINKRVKRDLVLS-GDLGSLYAMTQDKVFRLPVQECLSYPTCTQC 478
Query: 559 VGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPG 618
+ D YCGWC +E RCT + +C + + W + C A+T + R+
Sbjct: 479 RDSQDPYCGWCVVEGRCTRKAECPRAEEASHWLWSRS--KSCVAVTSAQPQNMSRRAQGE 536
Query: 619 MILQISGSLPSLSGM-EMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQD 677
+ L +S LP+LS E+ C +G + ARV G A CN P PP QD
Sbjct: 537 VQLTVS-PLPALSEEDELLCLFGESPPHPARVEGEA-----VICN--SPSSIPVTPPGQD 588
Query: 678 HVTVEMSVRVNGRNIVKANFT--IYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVS 735
HV V + + + NI ++ YDC + + + C SC+S +W C W + H C
Sbjct: 589 HVAVTIQLLLRRGNIFLTSYQYPFYDCRQAMSLEENLPCISCVSNRWTCQWDLRYHECR- 647
Query: 736 NQSRCEASPNPTS-------PQDCPRTLLSPLAPVPTGGSQNILVPLANTAFFQGAALEC 788
EASPNP CP+ L +P ++ N +G++L
Sbjct: 648 -----EASPNPEDGIVRAHMEDSCPQFLGPSPLVIPMNHETDVNFQGKNLDTVKGSSLHV 702
Query: 789 SFGLEEIFEAVWVNESVVRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYN 848
L + E V + ES + + ++ PL L +K + +DS + V +YN
Sbjct: 703 GSDLLKFMEPVTMQESGTFAFRTPKLSHDANETLPLHLYVKSY-GKNIDSK--LHVTLYN 759
Query: 849 CAMGSPDCSQCLGREDLGHLCMWSDGCRLRGPLQPMAGT---CPAPEIRAIEPLSGPLDG 905
C+ G DCS C + C W G + R + + T CP P I I+P +GPL G
Sbjct: 760 CSFGRSDCSLCRAANP-DYRCAWCGG-QSRCVYEALCNTTSECPPPVITRIQPETGPLGG 817
Query: 906 GTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVN 965
G +TI G NLG + D+ + + G C P+RY+VS IVCV A P +G V V+
Sbjct: 818 GIRITILGSNLGVQAGDIQR-ISVAGRNCSFQPERYSVSTRIVCVIEAAETPFTGGVEVD 876
Query: 966 A-SKEGKSRD--RFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPC 1022
K G+S +F++ P S+EP GP+AGGT +TIHG L GS+ V V
Sbjct: 877 VFGKLGRSPPNVQFTFQQPKPLSVEPQQGPQAGGTTLTIHGTHLDTGSQEDVRVTLNGVP 936
Query: 1023 TELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVS 1082
++ + + C A + + V + + + F Y +NPV+ A P RS S
Sbjct: 937 CKVTKFGAQLQCVTGPQATRGQMLLEVSYGGSPVPNPGIFFTYRENPVLRAFEPLRSFAS 996
Query: 1083 GGRTITVAGERFHMVQNVSMAVH----HIGREPTLCKVLNSTLITCPSPGALSNASAPVD 1138
GGR+I V G+ F ++Q +M V + P + L +T + + V
Sbjct: 997 GGRSINVTGQGFSLIQRFAMVVIAEPLQSWQPPREAESLQP--MTVVGTDYVFHNDTKVV 1054
Query: 1139 FF---INGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFS--TAKREKWIKHHPGE 1193
F + A + V E+ R +Y+P+P F T +K +
Sbjct: 1055 FLSPAVPEEPEAYNLTVLIEMDGHRALLRTEAGAFEYVPDPTFENFTGGVKKQVNK---- 1110
Query: 1194 PLTLVIHKEQDSLG--LQSHEYRVKIGQVSCDIQIVSDRIIHCSVNE--------SLGAA 1243
+IH +L + E +G C ++ +++ ++C E
Sbjct: 1111 ----LIHARGTNLNKAMTLQEAEAFVGAERCTMKTLTETDLYCEPPEVQPPPKRRQKRDT 1166
Query: 1244 VGQLP-ITIQVGNFNQTIATLQLGGSETAIIVSIVICSVLL-LLSVVALFVFC--TKSRR 1299
LP ++ G+ + ++ + + +S+++ V++ ++ V+A+ V+C KS++
Sbjct: 1167 THNLPEFIVKFGSREWVLGRVEYDTRVSDVPLSLILPLVIVPMVVVIAVSVYCYWRKSQQ 1226
Query: 1300 AERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTF 1359
AER ++K Q+E +E +R+ +K F +L +M D T +++ + GIP L+YK + R F
Sbjct: 1227 AEREYEKIKSQLEGLEESVRDRCKKEFTDLMIEMEDQTNDVHEA-GIPVLDYKTYTDRVF 1285
Query: 1360 FPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNN 1419
F LPS+ G T G+ IPE RP +E+ + FS+LLN+
Sbjct: 1286 F------------LPSK----DGDKDVMIT----GKLDIPEPRRPVVEQALYQFSNLLNS 1325
Query: 1420 KHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLIDASA-AKN 1478
K FLI F+H LE Q++F+ R + ASLLT+ALHGKLEYYT IM L ++L++ AKN
Sbjct: 1326 KSFLINFIHTLENQREFSARAKVYFASLLTVALHGKLEYYTDIMHTLFLELLEQYVVAKN 1385
Query: 1479 PKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKAR 1538
PKLMLRR+E+VVE+ML+NWMSIC+Y L+++ GEP + L AIK Q+ KG +DA+ KA+
Sbjct: 1386 PKLMLRRSETVVERMLSNWMSICLYQYLKDSAGEPLYKLFKAIKHQVEKGPVDAVQKKAK 1445
Query: 1539 YTLNEEWLLRENIEAKPRNLNVSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYS 1598
YTLN+ LL +++E P ++V Q G+D++ V+ ++ DT++QVKEKI++ + P S
Sbjct: 1446 YTLNDTGLLGDDVEYAPLTVSVIVQDEGVDAIPVKVLNCDTISQVKEKIIDQVYRGQPCS 1505
Query: 1599 QWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKK 1658
WPR + V LEW ST + IL DLD TS E K++NTL HY + +GA+L +S +
Sbjct: 1506 CWPRPDSVVLEWRPGST-AQILSDLDLTSQREGRWKRVNTLMHYNVRDGATLILSKVGVS 1564
Query: 1659 DNTLGRVKDLDTEKY---------FHLVLPTDELAEPKK---SHRQSHRKKVLPEIYLTR 1706
+DL E++ +HLV PTDE+ E K S ++ R K + EIYLTR
Sbjct: 1565 QQPEDSQQDLPGERHALLEEENRVWHLVRPTDEVDEGKSKRGSVKEKERTKAITEIYLTR 1624
Query: 1707 LLSTKGTLQKFLDDLFKAILSIREDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNS 1766
LLS KGTLQ+F+D+ F+++L+ PP AVKYFFDFL+EQAEK I D DT+HIWKTNS
Sbjct: 1625 LLSVKGTLQQFVDNFFQSVLAPGHAVPP-AVKYFFDFLDEQAEKHNIQDEDTIHIWKTNS 1683
Query: 1767 LPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAK 1826
LPLRFWVNILKNP F+FD+ + +DA LSVIAQ F+DAC+ ++ +L +DSP+NKLLYAK
Sbjct: 1684 LPLRFWVNILKNPHFIFDVHVHEVVDASLSVIAQTFMDACTRTEHKLSRDSPSNKLLYAK 1743
Query: 1827 EIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRP 1886
EI Y+K+V+ YYK I+ M +S+Q+MN HLAE SR + + NT VA+ ++Y+Y ++Y
Sbjct: 1744 EISTYKKMVEDYYKGIRQMVQVSDQDMNTHLAEISRAHTDSLNTLVALHQLYQYTQKYYD 1803
Query: 1887 QIMAALEANPTARRTQLQHKFEQVVALMEDNI 1918
+I+ ALE +P A++ QL + +Q+ A +E+ +
Sbjct: 1804 EIINALEEDPAAQKMQLAFRLQQIAAALENKV 1835
>gi|113722116 plexin A2 [Homo sapiens]
Length = 1894
Score = 889 bits (2296), Expect = 0.0
Identities = 638/1951 (32%), Positives = 972/1951 (49%), Gaps = 207/1951 (10%)
Query: 60 NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRR 119
N+ + G VY+ A+NR+Y+L+G NL+++ GP D+ C+ P + Q C
Sbjct: 51 NHLTVHQGTGAVYVGAINRVYKLTG-NLTIQVAHKTGPEEDNKSCYPPLIVQP-CSEVLT 108
Query: 120 LTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSM 179
LT+N NK+L +D + ++ CGS+YQG C+L R ++ + P+ + S
Sbjct: 109 LTNNVNKLLIIDYSENRLLACGSLYQGVCKLLRLDDLFILV-------EPSHKKEHYLSS 161
Query: 180 LNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIA 239
+N T+ V+ + G G +L +G G +FP +L + PE +
Sbjct: 162 VN------KTGTMYGVIVRSEGEDG-KLFIGTAVDGK-QDYFP---TLSSRKLPRDPESS 210
Query: 240 IRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSA----FLHPSDPPPGAQS 295
LD +L F L + L + + GF S FL P
Sbjct: 211 AM-LDY--ELHSDFVSSLIKIPSDTLALVSHFDIFYIYGFASGGFVYFLTVQPETPEG-- 265
Query: 296 YAYLALNSEARAGDKESQARSLLARIC-----------LPHG---AGGDAKKLTESYIQL 341
+A+NS AGD +R + R+C LP G AG + + L +Y+
Sbjct: 266 ---VAINS---AGDLFYTSR--IVRLCKDDPKFHSYVSLPFGCTRAGVEYRLLQAAYL-- 315
Query: 342 GLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIR 401
A GD ++ ++ + LFA+F + Q +ALCAF + I+
Sbjct: 316 -------AKPGDSLAQAFNITSQDDVLFAIFSKGQKQYHHPPDDSALCAFPIRAINLQIK 368
Query: 402 AARTACFV-EPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPL 460
+C+ E ++ +L VQ T N CG + PL P+
Sbjct: 369 ERLQSCYQGEGNLELNWLLGKDVQCTKAPVPIDDNF--------CGL-DINQPLGGSTPV 419
Query: 461 KATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQ--VVSRRVVTVAYG 516
+ ++ +TSVA N Y+ VF+GT +G+L KI + V V + G
Sbjct: 420 EGLTLYTTSRDRMTSVASYVYNGYSVVFVGTKSGKLKKIRADGPPHGGVQYEMVSVLKDG 479
Query: 517 EPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCT 576
P+ M F D YLY+M+ Q+ RV V +C ++TCG+C+ + D +CGWCAL C+
Sbjct: 480 SPILRDMAFS-IDQRYLYVMSERQVTRVPVESCEQYTTCGECLSSGDPHCGWCALHNMCS 538
Query: 577 LQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMA 636
+ C + + + + ++ S+C ++ V PS I V E+ ++ + P LS +A
Sbjct: 539 RRDKCQQAWEPNRFAASI---SQCVSLAVHPSSISV-SEHSRLLSLVVSDAPDLSA-GIA 593
Query: 637 CDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVRVN--GRNIVK 694
C +GN + V G G Q+ + P+D P P +QD +E+ +R G+ V
Sbjct: 594 CAFGN----LTEVEGQVSGSQVICISPGPKD-VPVIPLDQDWFGLELQLRSKETGKIFVS 648
Query: 695 ANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNPTS-PQDCP 753
F Y+CS H C SC+++ + C WC ++ C + + C + +DCP
Sbjct: 649 TEFKFYNCSA------HQLCLSCVNSAFRCHWCKYRNLCTHDPTTCSFQEGRINISEDCP 702
Query: 754 RTLLSPLAPVPTGGSQNILVPLANTAFFQGA--ALECSFGLEEIFE---AVWVNESVVRC 808
+ + + +P G + I + N Q EC ++ A+ N S V+C
Sbjct: 703 QLVPTEEILIPVGEVKPITLKARNLPQPQSGQRGYECVLNIQGAIHRVPALRFNSSSVQC 762
Query: 809 -DQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQCLGREDLGH 867
+ + + + +D+P+ + V +Y CA C CL + D
Sbjct: 763 QNSSYQYDGMDISNLAVDFAVVWNGNFIIDNPQDLKVHLYKCAAQRESCGLCL-KADRKF 821
Query: 868 LCMWSDG---CRLR----GPLQPMAG------TCPAPEIRAIEPLSGPLDGGTLLTIRGR 914
C W G C L P P C P+I I +SGP +GGT +TI G
Sbjct: 822 ECGWCSGERRCTLHQHCTSPSSPWLDWSSHNVKCSNPQITEILTVSGPPEGGTRVTIHGV 881
Query: 915 NLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPA-PGPLSGVVTVNASK----- 968
NLG S++AH V + GV C PLP Y ++E+IVC G A G SG V + +
Sbjct: 882 NLGLDFSEIAHHVQVAGVPCTPLPGEYIIAEQIVCEMGHALVGTTSGPVRLCIGECKPEF 941
Query: 969 EGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRT 1028
KS ++++V P V SL P GP++GGT +TI G+ L GS + V + + C R+
Sbjct: 942 MTKSHQQYTFVNPSVLSLNPIRGPESGGTMVTITGHYLGAGSSVAVYLGN-QTCEFYGRS 1000
Query: 1029 DTSIACTMPEGALP-APVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTI 1087
+ I C P + PVPV V +R V NL F Y+ +P + I P S SG +
Sbjct: 1001 MSEIVCVSPPSSNGLGPVPVSVSVDRAH-VDSNLQFEYIDDPRVQRIEPEWSIASGHTPL 1059
Query: 1088 TVAGERFHMVQNVSMAVHHIGREPT-LCKVLNSTLITCPSPGALSNASAPVDFFINGRAY 1146
T+ G ++Q + V G+E +CKV+N+T +TC +P ++ +D +
Sbjct: 1060 TITGFNLDVIQEPRIRVKFNGKESVNVCKVVNTTTLTCLAPSLTTDYRPGLDTVERPDEF 1119
Query: 1147 ADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKE-QDS 1205
+ LL + + Y PNP F + PG P+ L +
Sbjct: 1120 GFVFNNVQSLLIYNDT------KFIYYPNPTFELLSPTGVLDQKPGSPIILKGKNLCPPA 1173
Query: 1206 LGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATLQL 1265
G Y V IG+ C + + +++ N GQ + + VG + ++ +
Sbjct: 1174 SGGAKLNYTVLIGETPCAVTVSETQLLCEPPN-----LTGQHKVMVHVGGMVFSPGSVSV 1228
Query: 1266 GGSETAIIVSIVIC----SVLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIREE 1321
+ +IV S+LL++ ++ L + KSR + ++ +QM+ +ES++ E
Sbjct: 1229 ISDSLLTLPAIVSIAAGGSLLLIIVIIVLIAYKRKSRENDLTLKRLQMQMDNLESRVALE 1288
Query: 1322 IRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQ 1381
++ FAELQTD+ +LT +L+RS GIP+L+Y+ + R FP
Sbjct: 1289 CKEAFAELQTDINELTSDLDRS-GIPYLDYRTYAMRVLFPGI------------------ 1329
Query: 1382 GSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDR 1441
E HP+L E ++ + + ++E+ + LF+ L+NNK FL+ F+ LE Q+ F++RDR
Sbjct: 1330 ------EDHPVLRELEVQGNGQQHVEKALKLFAQLINNKVFLLTFIRTLELQRSFSMRDR 1383
Query: 1442 CSLASLLTIALHGKLEYYTSIMKELLVDLIDASAAK--NPKLMLRRTESVVEKMLTNWMS 1499
++ASL+ L G+LEY T ++K+LL DLID + +PKL+LRRTESV EKMLTNW +
Sbjct: 1384 GNVASLIMTGLQGRLEYATDVLKQLLSDLIDKNLENKNHPKLLLRRTESVAEKMLTNWFA 1443
Query: 1500 ICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLN 1559
++ L+E GEP F+L CAIKQQ+ KG IDAITG+ARY+L+E+ L+R+ IE K LN
Sbjct: 1444 FLLHKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIEYKTLILN 1503
Query: 1560 -VSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSY 1618
V+ + V+ ++ DT+TQVKEKIL+A KNVPYSQ PRA D+DLEW
Sbjct: 1504 CVNPDNENSPEIPVKVLNCDTITQVKEKILDAVYKNVPYSQRPRAVDMDLEWRQGRIARV 1563
Query: 1619 ILRDLDDTSVVEDGRKKLNTLAHYK------------------IPEGASLAMSLIDKKDN 1660
+L+D D T+ +E K+LNTL HY+ IP AS++ + I + D+
Sbjct: 1564 VLQDEDITTKIEGDWKRLNTLMHYQVSDRSVVALVPKQTSSYNIPASASISRTSISRYDS 1623
Query: 1661 TLGRVKDLDT---------------EKYFHLVLPTDELAEPKKSHRQSHRKKVLPEIYLT 1705
+ D+ K +HLV D + K+ R S K++ EIYLT
Sbjct: 1624 SFRYTGSPDSLRSRAPMITPDLESGVKVWHLVKNHDH-GDQKEGDRGS---KMVSEIYLT 1679
Query: 1706 RLLSTKGTLQKFLDDLFKAILSI--REDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWK 1763
RLL+TKGTLQKF+DDLF+ + S R PLA+KY FDFL+EQA++ I D D H WK
Sbjct: 1680 RLLATKGTLQKFVDDLFETLFSTVHRGSALPLAIKYMFDFLDEQADRHSIHDTDVRHTWK 1739
Query: 1764 TNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLL 1823
+N LPLRFWVN++KNPQFVFDI K DACLSV+AQ F+D+CS S+ +LGKDSP+NKLL
Sbjct: 1740 SNCLPLRFWVNVIKNPQFVFDIHKGSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLL 1799
Query: 1824 YAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKR 1883
YAK+IP Y+ V+RYY I + +S+Q+MNA+LAE+SR + EFN A+ EIY Y +
Sbjct: 1800 YAKDIPSYKSWVERYYADIAKLPAISDQDMNAYLAEQSRLHAVEFNMLSALNEIYSYVSK 1859
Query: 1884 YRPQIMAALEANPTARRTQLQHKFEQVVALM 1914
Y +++ ALE + ARR +L +K EQ++ M
Sbjct: 1860 YSEELIGALEQDEQARRQRLAYKVEQLINAM 1890
>gi|157738645 plexin A4 isoform 1 [Homo sapiens]
Length = 1894
Score = 887 bits (2292), Expect = 0.0
Identities = 630/1959 (32%), Positives = 959/1959 (48%), Gaps = 224/1959 (11%)
Query: 60 NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRR 119
N+ +D G +YL AVNR+Y+LS ++L + GP D+P C+ P++ Q +C P
Sbjct: 52 NHLVVDERTGHIYLGAVNRIYKLS-SDLKVLVTHETGPDEDNPKCYPPRIVQ-TCNEPLT 109
Query: 120 LTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSM 179
T+N NK+L +D + ++ CGS+YQG C+L R ++ + + V S+
Sbjct: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
Query: 180 LNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIA 239
V ++ N +L + G F P I+
Sbjct: 170 FGVIVSYSNLD--------------DKLFIATAVDGKPEYF---------------PTIS 200
Query: 240 IRSLDTRGDLAKLFTFDLN----------PSD------DNILKIKQGAKEQHKLGFVSAF 283
R L + +F + + PSD D + G + + F++
Sbjct: 201 SRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLT-- 258
Query: 284 LHPSD-PPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLG 342
L P PPG+ + KE S L R+C A ++ + G
Sbjct: 259 LQPEMVSPPGSTT--------------KEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSG 304
Query: 343 -----LQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVR 397
LQ A + G + R + V P + LF VF + Q +ALC F +
Sbjct: 305 VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIN 364
Query: 398 AAIRAARTACFV-EPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSI 456
I+ +C+ E D+ + + P L I LD A PL +
Sbjct: 365 DRIKERLQSCYRGEGTLDLAWLKVKDI----PCSSALLTIDDNFCGLDMNA-----PLGV 415
Query: 457 LQPLKATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGRLLKINLNESM-QVVSRRVVTV 513
++ PVF +TSV N++ F+GT +G+L KI ++ + V V
Sbjct: 416 SDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKIRVDGPRGNALQYETVQV 475
Query: 514 AYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALET 573
PV M F D LY+M+ Q+ RV V +C + +CG+C+G+ D +CGWC L
Sbjct: 476 VDPGPVLRDMAFSK-DHEQLYIMSERQLTRVPVESCGQYQSCGECLGSGDPHCGWCVLHN 534
Query: 574 RCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGM 633
CT ++ C S + + S + +C +TV P+ I V Q Y +++ + ++P LS
Sbjct: 535 TCTRKERCERSKEPRRFASEMK---QCVRLTVHPNNISVSQ-YNVLLVLETYNVPELSA- 589
Query: 634 EMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVRVN--GRN 691
+ C + + ++ + G G+QI + ++ N DH V++ ++ G
Sbjct: 590 GVNCTFED----LSEMDGLVVGNQIQCYSPAAKEVPRIITENGDHHVVQLQLKSKETGMT 645
Query: 692 IVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNPTS-PQ 750
+F Y+CS H +C SC+ + + C WC +H C + C P+
Sbjct: 646 FASTSFVFYNCS------VHNSCLSCVESPYRCHWCKYRHVCTHDPKTCSFQEGRVKLPE 699
Query: 751 DCPRTLLSPLAPVPTGGSQNILVPLANTAFFQGA--ALECSF---GLEEIFEAVWVNESV 805
DCP+ L VP + I + N Q EC G E+ A+ N S
Sbjct: 700 DCPQLLRVDKILVPVEVIKPITLKAKNLPQPQSGQRGYECILNIQGSEQRVPALRFNSSS 759
Query: 806 VRCDQVVL-HTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQCLGRED 864
V+C + + P+ L + +D+P V +Y C C CL + D
Sbjct: 760 VQCQNTSYSYEGMEINNLPVELTVVWNGHFNIDNPAQNKVHLYKCGAMRESCGLCL-KAD 818
Query: 865 LGHLCMWSDG---CRLRG----------PLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTI 911
C W G C LR L C P I I P++GP +GGT +TI
Sbjct: 819 PDFACGWCQGPGQCTLRQHCPAQESQWLELSGAKSKCTNPRITEIIPVTGPREGGTKVTI 878
Query: 912 RGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPA-PGPLSGVVTVNASK-- 968
RG NLG D+A V + GV C PL D Y +E+IVC G A P +G V + +
Sbjct: 879 RGENLGLEFRDIASHVKVAGVECSPLVDGYIPAEQIVCEMGEAKPSQHAGFVEICVAVCR 938
Query: 969 ---EGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTEL 1025
+S + ++ + L+P+ GP +GGT++TI G +L+ GS + V+ PC
Sbjct: 939 PEFMARSSQLYYFMTLTLSDLKPSRGPMSGGTQVTITGTNLNAGSNVVVMFGK-QPCLFH 997
Query: 1026 MRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGR 1085
R+ + I C + V V+ +R +H +L F Y+++P I I P S VSG
Sbjct: 998 RRSPSYIVCNTTSSDEVLEMKVSVQVDRAK-IHQDLVFQYVEDPTIVRIEPEWSIVSGNT 1056
Query: 1086 TITVAGERFHMVQNVSMAVHHIGREP-TLCKVLNSTLITCPSPGALSNASAPVDFFINGR 1144
I V G ++QN + H G+E +C+VLN+T +TC +P D
Sbjct: 1057 PIAVWGTHLDLIQNPQIRAKHGGKEHINICEVLNATEMTCQAPALALGPDHQSDLTERPE 1116
Query: 1145 AYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQD 1204
+ + + LL + Y PNP F ++ PG P+ L K ++
Sbjct: 1117 EFGFILDNVQSLLILNKTN------FTYYPNPVFEAFGPSGILELKPGTPIIL---KGKN 1167
Query: 1205 SL-----GLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQT 1259
+ G Y V +G+ C + + +++ S N +G+ + +VG +
Sbjct: 1168 LIPPVAGGNVKLNYTVLVGEKPCTVTVSDVQLLCESPN-----LIGRHKVMARVGGMEYS 1222
Query: 1260 IATLQLGGSETA---IIVSIVICSVLLLLSVVALFV-FCTKSRRAERYWQKTLLQMEEME 1315
+ + IVSI + LL++ +VA+ + + KSR ++ ++ +QM+ +E
Sbjct: 1223 PGMVYIAPDSPLSLPAIVSIAVAGGLLIIFIVAVLIAYKRKSRESDLTLKRLQMQMDNLE 1282
Query: 1316 SQIREEIRKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPS 1375
S++ E ++ FAELQTD+ +LT +L+ + GIPFL+Y+ + R FP
Sbjct: 1283 SRVALECKEAFAELQTDIHELTSDLDGA-GIPFLDYRTYTMRVLFPGI------------ 1329
Query: 1376 QTLNSQGSSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKD 1435
E HP+L + ++P + +E+G+ LF+ L+NNK FL+ F+ LE Q+
Sbjct: 1330 ------------EDHPVLRDLEVPGYRQERVEKGLKLFAQLINNKVFLLSFIRTLESQRS 1377
Query: 1436 FAVRDRCSLASLLTIALHGKLEYYTSIMKELLVDLIDAS--AAKNPKLMLRRTESVVEKM 1493
F++RDR ++ASL+ L KLEY T ++K+LL DLID + + +PKL+LRRTESV EKM
Sbjct: 1378 FSMRDRGNVASLIMTVLQSKLEYATDVLKQLLADLIDKNLESKNHPKLLLRRTESVAEKM 1437
Query: 1494 LTNWMSICMYSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEA 1553
LTNW + +Y L+E GEP F L CAIKQQ+ KG IDAITG+ARY+L+E+ L+R+ I+
Sbjct: 1438 LTNWFTFLLYKFLKECAGEPLFSLFCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDY 1497
Query: 1554 KPRNLN-VSFQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFA 1612
K L+ VS + V+ ++ DT+TQVKEKIL+A KNVP S P+A D+DLEW
Sbjct: 1498 KTLVLSCVSPDNANSPEVPVKILNCDTITQVKEKILDAIFKNVPCSHRPKAADMDLEWRQ 1557
Query: 1613 SSTQSYILRDLDDTSVVEDGRKKLNTLAHYKIPEGASLAMSLIDKK--------DNTLGR 1664
S IL+D D T+ +E+ K+LNTLAHY++P+G+ +A L+ K+ ++T+ R
Sbjct: 1558 GSGARMILQDEDITTKIENDWKRLNTLAHYQVPDGSVVA--LVSKQVTAYNAVNNSTVSR 1615
Query: 1665 VK--------------------------DLDT-EKYFHLVLPTDELAEPKKSHRQSHRKK 1697
DL++ K +HLV E + K+ R S K
Sbjct: 1616 TSASKYENMIRYTGSPDSLRSRTPMITPDLESGVKMWHLV-KNHEHGDQKEGDRGS---K 1671
Query: 1698 VLPEIYLTRLLSTKGTLQKFLDDLFKAILSI--REDKPPLAVKYFFDFLEEQAEKRGISD 1755
++ EIYLTRLL+TKGTLQKF+DDLF+ I S R PLA+KY FDFL+EQA+K GI D
Sbjct: 1672 MVSEIYLTRLLATKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHGIHD 1731
Query: 1756 PDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGK 1815
P H WK+N LPLRFWVN++KNPQFVFDI K DACLSV+AQ F+D+CS S+ +LGK
Sbjct: 1732 PHVRHTWKSNCLPLRFWVNMIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHRLGK 1791
Query: 1816 DSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMA 1875
DSP+NKLLYAK+IP Y+ V+RYY I M +S+Q+MNA+LAE+SR + NEFNT A++
Sbjct: 1792 DSPSNKLLYAKDIPSYKNWVERYYSDIGKMPAISDQDMNAYLAEQSRMHMNEFNTMSALS 1851
Query: 1876 EIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALM 1914
EI+ Y +Y +I+ L+ + + +L +K EQV+ LM
Sbjct: 1852 EIFSYVGKYSEEILGPLDHDDQCGKQKLAYKLEQVITLM 1890
>gi|49355818 plexin A1 [Homo sapiens]
Length = 1873
Score = 861 bits (2225), Expect = 0.0
Identities = 631/1947 (32%), Positives = 947/1947 (48%), Gaps = 216/1947 (11%)
Query: 69 GTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKIL 128
G VY+ AVNR+Y+LSG NL+L GPV D+ C+ P Q SC H TDN NK+L
Sbjct: 38 GEVYVGAVNRIYKLSG-NLTLLRAHVTGPVEDNEKCYPPPSVQ-SCPHGLGSTDNVNKLL 95
Query: 129 QLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPN 188
LD ++ CGS QG CQ R ++ + P + S + A
Sbjct: 96 LLDYAANRLLACGSASQGICQFLRLDDLFKLG-------EPHHRKEHYLSSVQEAG---- 144
Query: 189 ASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGD 248
S G+++ G G ++L VG G F P ++ R L +
Sbjct: 145 -SMAGVLIAGPPGQGQAKLFVGTPIDGKSEYF---------------PTLSSRRLMANEE 188
Query: 249 LAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALNSEARAG 308
A +F F + + ++K + K + S Y L L+++ +
Sbjct: 189 DADMFGF-VYQDEFVSSQLKIPSDTLSKFPAFDIYYVYSFRSEQFVYYLTLQLDTQLTSP 247
Query: 309 DKESQA--RSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGR----------GDLYS 356
D + S + R+C+ D K + +G + AG R G +
Sbjct: 248 DAAGEHFFTSKIVRLCVD-----DPKFYSYVEFPIGCEQAGVEYRLVQDAYLSRPGRALA 302
Query: 357 RLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVV 416
+ + + LF VF + Q + +ALC F ++ I+ +C+ +
Sbjct: 303 HQLGLAEDEDVLFTVFAQGQKNRVKPPKESALCLFTLRAIKEKIKERIQSCYRGEGKLSL 362
Query: 417 AVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVF--RAPGLTSV 474
L + G +N LQ + CG Q PL ++ TP+F + GLT+V
Sbjct: 363 PWLLNKELGC-------INSPLQIDDDFCGQDFNQ-PLGGTVTIEGTPLFVDKDDGLTAV 414
Query: 475 AVASVNNYTAVFLGTVNGRLLKINLNES----MQVVSRRVVTVAYGEPVHHVMQFDPADS 530
A T VF GT +GR+ KI ++ S ++ V G P+ + P +
Sbjct: 415 AAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSP-NH 473
Query: 531 GYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQ-QHF 589
YLY MT Q+ RV V +C +++C C+G+ D +CGWC L + C+ + C + + Q F
Sbjct: 474 QYLYAMTEKQVTRVPVESCVQYTSCELCLGSRDPHCGWCVLHSICSRRDACERADEPQRF 533
Query: 590 WTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARV 649
+ C +TV P + V ++LQ + ++P LS + C + + + + +
Sbjct: 534 AADLLQ----CVQLTVQPRNVSVTMSQVPLVLQ-AWNVPDLSA-GVNCSFEDFTESESVL 587
Query: 650 PGPAFGHQIAYCNLLPRDQFPPFPPNQDH---VTVEMSVRVNGRNIVKANFTIYDCSRTA 706
+C + P Q V + + + G+ +F Y+CS
Sbjct: 588 EDGRI-----HCRSPSAREVAPITRGQGDQRVVKLYLKSKETGKKFASVDFVFYNCS--- 639
Query: 707 QVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNPTS-PQDCPRTLLSPLAPVPT 765
H +C SC++ +PC WC +H C N + C + +DCP+ L S VP
Sbjct: 640 ---VHQSCLSCVNGSFPCHWCKYRHVCTHNVADCAFLEGRVNVSEDCPQILPSTQIYVPV 696
Query: 766 GGSQNILVPLANTAFFQGA--ALECSF---GLEEIFEAVWVNESVVRCDQVVLHTTRKSQ 820
G + I + N Q EC F G A+ N S ++C Q ++ +
Sbjct: 697 GVVKPITLAARNLPQPQSGQRGYECLFHIPGSPARVTALRFNSSSLQC-QNSSYSYEGND 755
Query: 821 V--FPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQCLGREDLGHLCMWSDG---C 875
V P++L + +D+P+ + +Y C C CL + D C W C
Sbjct: 756 VSDLPVNLSVVWNGNFVIDNPQNIQAHLYKCPALRESCGLCL-KADPRFECGWCVAERRC 814
Query: 876 RLRG------PLQPM-----AGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVA 924
LR P M + C P+I + P +GP GGT LTI G NLG R DV
Sbjct: 815 SLRHHCAADTPASWMHARHGSSRCTDPKILKLSPETGPRQGGTRLTITGENLGLRFEDVR 874
Query: 925 HGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGKSRD---------- 974
GV +G V C P+ Y +E+IVC G A S V +A E RD
Sbjct: 875 LGVRVGKVLCSPVESEYISAEQIVCEIGDA----SSVRAHDALVEVCVRDCSPHYRALSP 930
Query: 975 -RFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTSIA 1033
RF++V P + + P+ GP +GGT I I G+ L+ GS++ V V PC+ R I
Sbjct: 931 KRFTFVTPTFYRVSPSRGPLSGGTWIGIEGSHLNAGSDVAVSVGGR-PCSFSWRNSREIR 989
Query: 1034 CTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITVAGER 1093
C P G P P+ + R + + + Y ++P I I P S SGG +TV G
Sbjct: 990 CLTPPGQSPGSAPIIININRAQLTNPEVKYNYTEDPTILRIDPEWSINSGGTLLTVTGTN 1049
Query: 1094 FHMVQNVSMAVHHIGRE-PTLCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAV 1152
V+ + + G E C V N T + C +P + +P + DE+
Sbjct: 1050 LATVREPRIRAKYGGIERENGCLVYNDTTMVCRAPSVANPVRSPPEL----GERPDELGF 1105
Query: 1153 AEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQDSL----GL 1208
+ + + F Y P+P ++ P PL L K ++ L G
Sbjct: 1106 VMDNVRSLLVLNSTSFL--YYPDPVLEPLSPTGLLELKPSSPLIL---KGRNLLPPAPGN 1160
Query: 1209 QSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATLQLGGS 1268
Y V IG C + + +++ + N GQ +T++ G F + TLQ+
Sbjct: 1161 SRLNYTVLIGSTPCTLTVSETQLLCEAPN-----LTGQHKVTVRAGGFEFSPGTLQVYSD 1215
Query: 1269 ETAIIVSIVICS----VLLLLSVVALFVFCTKSRRAERYWQKTLLQMEEMESQIREEIRK 1324
+ +IV +LLL+ V L + KSR A+R ++ LQM+ +ES++ E ++
Sbjct: 1216 SLLTLPAIVGIGGGGGLLLLVIVAVLIAYKRKSRDADRTLKRLQLQMDNLESRVALECKE 1275
Query: 1325 GFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSS 1384
FAELQTD+ +LT +L+ + GIPFL+Y+ + R FP
Sbjct: 1276 AFAELQTDIHELTNDLDGA-GIPFLDYRTYAMRVLFPGI--------------------- 1313
Query: 1385 QAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSL 1444
E HP+L E ++ + N+E+ ++LF LL KHFL+ F+ LE Q+ F++RDR ++
Sbjct: 1314 ---EDHPVLKEMEV----QANVEKSLTLFGQLLTKKHFLLTFIRTLEAQRSFSMRDRGNV 1366
Query: 1445 ASLLTIALHGKLEYYTSIMKELLVDLIDAS--AAKNPKLMLRRTESVVEKMLTNWMSICM 1502
ASL+ AL G++EY T ++K+LL DLI+ + + +PKL+LRRTESV EKMLTNW + +
Sbjct: 1367 ASLIMTALQGEMEYATGVLKQLLSDLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLL 1426
Query: 1503 YSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLN-VS 1561
Y L+E GEP F+L CAIKQQ+ KG IDAITG+ARY+L+E+ L+R+ I+ K LN V+
Sbjct: 1427 YKFLKECAGEPLFMLYCAIKQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLNCVN 1486
Query: 1562 FQGCGMDSLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILR 1621
+ + V+ +D DT+TQ KEK+L+A K VPYSQ P+A D+DLEW IL+
Sbjct: 1487 PENENAPEVPVKGLDCDTVTQAKEKLLDAAYKGVPYSQRPKAADMDLEWRQGRMARIILQ 1546
Query: 1622 DLDDTSVVEDGRKKLNTLAHYKIPEGASLAM-----------------SLIDKKDNTLGR 1664
D D T+ +++ K+LNTLAHY++ +G+S+A+ + + ++ L
Sbjct: 1547 DEDVTTKIDNDWKRLNTLAHYQVTDGSSVALVPKQTSAYNISNSSTFTKSLSRYESMLRT 1606
Query: 1665 VKDLDT---------------EKYFHLVLPTDELAEPKKSHRQSHRKKVLPEIYLTRLLS 1709
D+ K +HLV D L + ++ R S K++ EIYLTRLL+
Sbjct: 1607 ASSPDSLRSRTPMITPDLESGTKLWHLVKNHDHL-DQREGDRGS---KMVSEIYLTRLLA 1662
Query: 1710 TKGTLQKFLDDLFKAILSI--REDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSL 1767
TKGTLQKF+DDLF+ I S R PLA+KY FDFL+EQA+K I D D H WK+N L
Sbjct: 1663 TKGTLQKFVDDLFETIFSTAHRGSALPLAIKYMFDFLDEQADKHQIHDADVRHTWKSNCL 1722
Query: 1768 PLRFWVNILKNPQFVFDIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKE 1827
PLRFWVN++KNPQFVFDI K DACLSV+AQ F+D+CS S+ +LGKDSP+NKLLYAK+
Sbjct: 1723 PLRFWVNVIKNPQFVFDIHKNSITDACLSVVAQTFMDSCSTSEHKLGKDSPSNKLLYAKD 1782
Query: 1828 IPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQ 1887
IP Y+ V+RYY I M +S+Q+M+A+LAE+SR + ++FN+ A+ EIY Y +Y+ +
Sbjct: 1783 IPNYKSWVERYYADIAKMPAISDQDMSAYLAEQSRLHLSQFNSMSALHEIYSYITKYKDE 1842
Query: 1888 IMAALEANPTARRTQLQHKFEQVVALM 1914
I+AALE + ARR +L+ K EQVV M
Sbjct: 1843 ILAALEKDEQARRQRLRSKLEQVVDTM 1869
>gi|59710104 plexin A3 [Homo sapiens]
Length = 1871
Score = 860 bits (2223), Expect = 0.0
Identities = 637/1994 (31%), Positives = 970/1994 (48%), Gaps = 240/1994 (12%)
Query: 35 LLLLLGAARAGALEIQ--RRFP-SPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEA 91
LLLLL A GAL + R F + T + A+ G V++ AVNR+++L+ L A
Sbjct: 6 LLLLLFLAVGGALGNRPFRAFVVTDTTLTHLAVHRVTGEVFVGAVNRVFKLAPNLTELRA 65
Query: 92 EAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLR 151
GPV D+ C+ P + C H DN NK+L +D +V CGSI+QG CQ
Sbjct: 66 HVT-GPVEDNARCYPPPSMRV-CAHRLAPVDNINKLLLIDYAARRLVACGSIWQGICQFL 123
Query: 152 RRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLLVGA 211
R ++ + EP L+ A P+ S G+++ G G S+L VG
Sbjct: 124 RLDDLFKLG----------EPHHRKEHYLS-GAQEPD-SMAGVIVEQ--GQGPSKLFVGT 169
Query: 212 TYTGYGSSFFPRNRSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLN----------PSD 261
G F P ++ R L + D A +F+ PSD
Sbjct: 170 AVDGKSEYF---------------PTLSSRKLISDEDSADMFSLVYQDEFVSSQIKIPSD 214
Query: 262 DNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAY---LALNSEARAGDKESQA--RS 316
L + + GFVSA S+ Y L L+++ D + S
Sbjct: 215 T--LSLYPAFDIYYIYGFVSA------------SFVYFLTLQLDTQQTLLDTAGEKFFTS 260
Query: 317 LLARICLPHGAGGDAKKLTESYIQLGLQC------------AGGAGRGDLYSRLVSVFPA 364
+ R+C GD++ SY++ + C A A G L ++ + V
Sbjct: 261 KIVRMC-----AGDSEFY--SYVEFPIGCSWRGVEYRLVQSAHLAKPGLLLAQALGVPAD 313
Query: 365 RERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQ 424
+ LF +F + Q + A+ LC F +++ A IR +C+ + L ++
Sbjct: 314 EDVLFTIFSQGQKNRASPPRQTILCLFTLSNINAHIRRRIQSCY---RGEGTLALPWLLN 370
Query: 425 GTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFR--APGLTSVAVASVNNY 482
P +N +Q CG L PL L ++ P+ G+ SVA + +
Sbjct: 371 KELPC----INTPMQINGNFCGLV-LNQPLGGLHVIEGLPLLADSTDGMASVAAYTYRQH 425
Query: 483 TAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMA 542
+ VF+GT +G L K+ ++ V V G P+ + F P D ++YL++ Q++
Sbjct: 426 SVVFIGTRSGSLKKVRVDGFQDAHLYETVPVVDGSPILRDLLFSP-DHRHIYLLSEKQVS 484
Query: 543 RVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPA 602
++ V C + +C C+G+ D +CGWC L RC + C +S H +E S+C
Sbjct: 485 QLPVETCEQYQSCAACLGSGDPHCGWCVLRHRCCREGACLGASAPH---GFAEELSKCVQ 541
Query: 603 MTVLPSEIDVRQEYPGMILQIS-GSLPSLS-GMEMACDYGNNIRTVARVPGPAF--GHQI 658
+ V P+ + V PG+ L ++ ++P LS G+ A + V G +
Sbjct: 542 VRVRPNNVSVTS--PGVQLTVTLHNVPDLSAGVSCAFEAAAENEAVLLPSGELLCPSPSL 599
Query: 659 AYCNLLPRDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCL 718
L R ++ E VR G A+F Y+CS +C SC+
Sbjct: 600 QELRALTRGHGATRTVRLQLLSKETGVRFAG-----ADFVFYNCSVL------QSCMSCV 648
Query: 719 SAQWPCFWCSQQHSCVSNQSRCEASPNPT-SPQDCPRTLLSPLAPVPTGGSQNILVPLAN 777
+ +PC WC +H+C S C SP+ CP L S +P G Q + + N
Sbjct: 649 GSPYPCHWCKYRHTCTSRPHECSFQEGRVHSPEGCPEILPSGDLLIPVGVMQPLTLRAKN 708
Query: 778 TAFFQGAA--LECSF---GLEEIFEAVWVNESVVRCDQV-VLHTTRKSQVFPLSLQLKGR 831
Q EC G ++ AV N S V+C + + L +
Sbjct: 709 LPQPQSGQKNYECVVRVQGRQQRVPAVRFNSSSVQCQNASYSYEGDEHGDTELDFSVVWD 768
Query: 832 PARFLDSPEPMTVMVYNCAMGSPDCSQCLGREDLGHLCMW---SDGCRLRG--------- 879
+D P ++Y C P C CL + D C W C+LR
Sbjct: 769 GDFPIDKPPSFRALLYKCWAQRPSCGLCL-KADPRFNCGWCISEHRCQLRTHCPAPKTNW 827
Query: 880 -PLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLP 938
L C P I I PL GP +GGT +TI G NLG +V G+ + GV C +P
Sbjct: 828 MHLSQKGTRCSHPRITQIHPLVGPKEGGTRVTIVGDNLGLLSREV--GLRVAGVRCNSIP 885
Query: 939 DRYTVSEEIVC------VTGPAPGPLSGVV-TVNASKEGKSRDRFSYVLPLVHSLEPTMG 991
Y +E IVC V P PGP+ V +A +S +S+V P + P+ G
Sbjct: 886 AEYISAERIVCEMEESLVPSPPPGPVELCVGDCSADFRTQSEQVYSFVTPTFDQVSPSRG 945
Query: 992 PKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTSIACTMPEGAL-PAPVPVCVR 1050
P +GGTR+TI G+ L GS + V V D++ C + R +I C P L P+ P+ +
Sbjct: 946 PASGGTRLTISGSSLDAGSRVTVTVRDSE-CQFVRRDAKAIVCISPLSTLGPSQAPITLA 1004
Query: 1051 FERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGRE 1110
+R L + Y Q+P +T + P S ++G ITV+G VQ + + G E
Sbjct: 1005 IDRANISSPGLIYTYTQDPTVTRLEPTWSIINGSTAITVSGTHLLTVQEPRVRAKYRGIE 1064
Query: 1111 PT-LCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRG-SRF 1168
T C+V+N T + C +PG P RA + LLD + R +R
Sbjct: 1065 TTNTCQVINDTAMLCKAPGIFLGRPQP-------RAQGEHPDEFGFLLDHVQTARSLNRS 1117
Query: 1169 RLDYLPNPQFSTAKREKWIKHHPGEPLTLV-IHKEQDSLGLQSHEYRVKIGQVSCDIQIV 1227
Y P+P F + PG + L + + G Y V IG C + +
Sbjct: 1118 SFTYYPDPSFEPLGPSGVLDVKPGSHVVLKGKNLIPAAAGSSRLNYTVLIGGQPCSLTVS 1177
Query: 1228 SDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATLQLGGSETAIIVSIVICSV---LLL 1284
+++ S +++ G+ P+ + VG + TL + + +++ + LLL
Sbjct: 1178 DTQLLCDSPSQT-----GRQPVMVLVGGLEFWLGTLHISAERALTLPAMMGLAAGGGLLL 1232
Query: 1285 LSVVALFV-FCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNRS 1343
L++ A+ V + K++ A+R ++ LQM+ +ES++ E ++ FAELQTD+ +LT ++
Sbjct: 1233 LAITAVLVAYKRKTQDADRTLKRLQLQMDNLESRVALECKEAFAELQTDINELTNHMDEV 1292
Query: 1344 QGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESCR 1403
Q IPFL+Y+ + R FP E HP+L E P
Sbjct: 1293 Q-IPFLDYRTYAVRVLFP------------------------GIEAHPVLKELDTP---- 1323
Query: 1404 PNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSIM 1463
PN+E+ + LF LL+++ F++ F+H LE Q F++RDR ++ASL +AL +L+Y T ++
Sbjct: 1324 PNVEKALRLFGQLLHSRAFVLTFIHTLEAQSSFSMRDRGTVASLTMVALQSRLDYATGLL 1383
Query: 1464 KELLVDLIDAS--AAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAI 1521
K+LL DLI+ + + +PKL+LRRTESV EKMLTNW + ++ L+E GEP FLL CAI
Sbjct: 1384 KQLLADLIEKNLESKNHPKLLLRRTESVAEKMLTNWFTFLLHKFLKECAGEPLFLLYCAI 1443
Query: 1522 KQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLN-VSFQGCGMDSLSVRAMDTDTL 1580
KQQ+ KG IDAITG+ARY+L+E+ L+R+ I+ K L+ V + G + V+ ++ D++
Sbjct: 1444 KQQMEKGPIDAITGEARYSLSEDKLIRQQIDYKTLTLHCVCPENEGSAQVPVKVLNCDSI 1503
Query: 1581 TQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNTLA 1640
TQ K+K+L+ K +PYSQ P+AED+DLEW IL+D D T+ +E K+LN+LA
Sbjct: 1504 TQAKDKLLDTVYKGIPYSQRPKAEDMDLEWRQGRMTRIILQDEDVTTKIECDWKRLNSLA 1563
Query: 1641 HYKIPEGASLAMSLIDKK------------DNTLGRVKDL-------------------D 1669
HY++ +G+ +A L+ K+ +L R + L D
Sbjct: 1564 HYQVTDGSLVA--LVPKQVSAYNMANSFTFTRSLSRYESLLRTASSPDSLRSRAPMITPD 1621
Query: 1670 TE---KYFHLVLPTDELAEPKKSHRQSHR-KKVLPEIYLTRLLSTKGTLQKFLDDLFKAI 1725
E K +HLV D HR+ R K++ EIYLTRLL+TKGTLQKF+DDLF+ +
Sbjct: 1622 QETGTKLWHLVKNHDH-----ADHREGDRGSKMVSEIYLTRLLATKGTLQKFVDDLFETV 1676
Query: 1726 LSI--REDKPPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVF 1783
S R PLA+KY FDFL+EQA++R ISDPD H WK+N LPLRFWVN++KNPQFVF
Sbjct: 1677 FSTAHRGSALPLAIKYMFDFLDEQADQRQISDPDVRHTWKSNCLPLRFWVNVIKNPQFVF 1736
Query: 1784 DIDKTDHIDACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQ 1843
DI K DACLSV+AQ F+D+CS S+ +LGKDSP+NKLLYAK+IP Y+ V+RYY+ I
Sbjct: 1737 DIHKNSITDACLSVVAQTFMDSCSTSEHRLGKDSPSNKLLYAKDIPNYKSWVERYYRDIA 1796
Query: 1844 DMTPLSEQEMNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQL 1903
M +S+Q+M+A+L E+SR + ++F+ A+ E+Y Y +YR +I+ AL+ + + R+ +L
Sbjct: 1797 KMASISDQDMDAYLVEQSRLHASDFSVLSALNELYFYVTKYRQEILTALDRDASCRKHKL 1856
Query: 1904 QHKFEQVVALMEDN 1917
+ K EQ+++L+ +
Sbjct: 1857 RQKLEQIISLVSSD 1870
>gi|194272180 plexin B1 [Homo sapiens]
Length = 2135
Score = 759 bits (1961), Expect = 0.0
Identities = 471/1199 (39%), Positives = 674/1199 (56%), Gaps = 131/1199 (10%)
Query: 806 VRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQC-LGRED 864
V C Q L + L L+ +DS E + V++Y+C++G DCS+C
Sbjct: 979 VTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQ 1038
Query: 865 LGHLCMWSDGCRLR-------GPLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLG 917
G C+W +G R R G + +A CPAP I ++EPL+GP+DGGT +TIRG NLG
Sbjct: 1039 YG--CVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLG 1096
Query: 918 RRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGK--SRDR 975
+ + DV V + GV C Y VS +VC+TG + ++G V G+ S
Sbjct: 1097 QHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHD 1156
Query: 976 FSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVG--SELQVLVNDTDPCTELMRTDTS-I 1032
F+Y P VHS+ P GP+AGGTR+T++G+ L G +++V+V D PC L + +
Sbjct: 1157 FAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD-QPCHLLPEQQSEQL 1215
Query: 1033 ACTMPEGALPAPVPVCVRFERRGCVHGNLT---FWYMQNPVITAISPRRSPVSGGRTITV 1089
C PA +PV V F G L F Y +P IT+ P +S +SGGR I V
Sbjct: 1216 RCETSPRPTPATLPVAVWF---GATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREICV 1272
Query: 1090 AGERFHMVQNVSMAVHHIGR--------------------------------EPTLCKVL 1117
G+ +VQ + V + R EP C V
Sbjct: 1273 RGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEP--CHVN 1330
Query: 1118 NSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQ 1177
+S LITC +P P D ++ D + L+P + L L NP+
Sbjct: 1331 SSQLITCRTPAL---PGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPL-NPE 1386
Query: 1178 FSTAKREKWIKHHPGEPLTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSV- 1236
T +H PG + + E L + E IG C ++ ++ ++C
Sbjct: 1387 DPTMP----FRHKPGSVFS--VEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
Query: 1237 -------NESLGAAVGQLP-ITIQVGNFNQTIATLQLGGSE-----TAIIVSIVICSVLL 1283
+ +L A LP T+Q+GN ++ +Q G A V + + + LL
Sbjct: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
Query: 1284 LLSVVAL-FVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNR 1342
L V+ + ++ KS++A R ++K +Q+E +ES +R+ +K F +L T+MTDLT +L
Sbjct: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
Query: 1343 SQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESC 1402
S GIPFL+YK + R FFP PL + +PES
Sbjct: 1561 S-GIPFLDYKVYAERIFFP------------------------GHRESPLHRDLGVPESR 1595
Query: 1403 RPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSI 1462
RP +E+G+ S+LLN+K FL F+H LE Q+ F+ RDR +ASLLT+ALHGKLEY+T I
Sbjct: 1596 RPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDI 1655
Query: 1463 MKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIK 1522
++ LL DL+ AKNPKLMLRRTE+VVEK+LTNWMSIC+Y+ +R++VGEP ++L IK
Sbjct: 1656 LRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIK 1715
Query: 1523 QQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSFQ---GCG-MDSLSVRAMDTD 1578
Q++KG +D++TGKA+YTLN+ LLRE++E +P LN G G + V+ +D D
Sbjct: 1716 HQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCD 1775
Query: 1579 TLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNT 1638
T++Q KEK+L+ K VP +Q P +D+EW + IL D D TS V+ ++LNT
Sbjct: 1776 TISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNT 1835
Query: 1639 LAHYKIPEGASLAMS-------LIDKKDNTLGR----VKDLDTE--KYFHLVLPTDELAE 1685
L HYK+P+GA++A+ L + +D G ++D+D + +HLV P+DE E
Sbjct: 1836 LQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDE-PE 1894
Query: 1686 PKKSHRQS------HRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKY 1739
P + R S R K +PEIYLTRLLS KGTLQKF+DDLF+ ILS P LAVKY
Sbjct: 1895 PPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVP-LAVKY 1953
Query: 1740 FFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIA 1799
FFD L+EQA++ GISD DT+HIWKTNSLPLRFW+NI+KNPQFVFD+ +D++DA L VIA
Sbjct: 1954 FFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIA 2013
Query: 1800 QAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAE 1859
Q F+DAC+++D +LG+DSP NKLLYA++IP Y+++V+RYY I+ P S+QEMN+ LAE
Sbjct: 2014 QTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAE 2073
Query: 1860 ESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNI 1918
S Y + VA+ E+YKY +Y QI+ ALE + TA++ QL ++ +Q+ A +E+ +
Sbjct: 2074 LSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKV 2132
Score = 251 bits (642), Expect = 4e-66
Identities = 222/742 (29%), Positives = 325/742 (43%), Gaps = 107/742 (14%)
Query: 54 PSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQAS 113
P+ T + A D +GT+YL A N L+QLS L LEA + GPV DS C P +P
Sbjct: 30 PNGTYLQHLARDPTSGTLYLGATNFLFQLS-PGLQLEATVSTGPVLDSRDCLPPVMPD-- 86
Query: 114 CEHPR-RLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEP 172
E P+ + T+N N++L + PG +VVCGS++QG C+ RR G + + +R P P
Sbjct: 87 -ECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLR------PERP 137
Query: 173 VTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLL-VGATYTGYGSSFFPRNRSLEDHR 231
VAAN P STVGLV A G G LL VG YT G
Sbjct: 138 ----GDTQYVAANDPAVSTVGLV---AQGLAGEPLLFVGRGYTSRGVG------------ 178
Query: 232 FENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPP 291
P I R+L A S + K+ G ++ FVSAF
Sbjct: 179 -GGIPPITTRALWPPDPQAAF-------SYEETAKLAVGRLSEYSHHFVSAFAR------ 224
Query: 292 GAQSYAYLALNSEARAGDKESQA-RSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAG 350
GA +Y +L L + +A +S+A R+ ++R+CL + SY++L L C GG
Sbjct: 225 GASAY-FLFLRRDLQA---QSRAFRAYVSRVCL-------RDQHYYSYVELPLACEGGR- 272
Query: 351 RGDLYSRLVSVFPARER-------LFAVFE--------RPQGSPAARAAPAALCAFRFAD 395
Y + + A R LFA F RP + A + +ALCAF +
Sbjct: 273 ----YGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDE 328
Query: 396 VRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPA-CERKLN---IQLQPEQLD---CGAA 448
V R AC+ GT A E +N QL + LD CG+
Sbjct: 329 VDRLANRTRDACYTREG--------RAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSD 380
Query: 449 HLQHPLSILQPLKATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVV 506
H P++ PL+ATP+ PG LT+VAV + +T FLG G+L ++ L
Sbjct: 381 HTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGH 440
Query: 507 SRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYC 566
++ G V + FD +LY+MT + +V VA+C H C C+ D YC
Sbjct: 441 PYSTQSIQQGSAVSRDLTFDGTFE-HLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYC 499
Query: 567 GWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGS 626
GWC L RC+ + +C+ W + + C + + R+E + L +
Sbjct: 500 GWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDL 559
Query: 627 LPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVR 686
P G +C +G + ++ A + G C + P P D+V+V + +R
Sbjct: 560 PPLWPGESYSCHFGEH-QSPALLTGSG-----VMCPSPDPSEAPVLPRGADYVSVSVELR 613
Query: 687 VNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNP 746
I K + + YDC ++ P C +C+S++W C WC QH C ++++ C+A P
Sbjct: 614 FGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC-THKASCDAGPMV 672
Query: 747 TSPQDCPRTLLSPLAPVPTGGS 768
S Q L+SP P G S
Sbjct: 673 ASHQS---PLVSPDPPARGGPS 691
>gi|40254442 plexin B1 [Homo sapiens]
Length = 2135
Score = 759 bits (1961), Expect = 0.0
Identities = 471/1199 (39%), Positives = 674/1199 (56%), Gaps = 131/1199 (10%)
Query: 806 VRCDQVVLHTTRKSQVFPLSLQLKGRPARFLDSPEPMTVMVYNCAMGSPDCSQC-LGRED 864
V C Q L + L L+ +DS E + V++Y+C++G DCS+C
Sbjct: 979 VTCQQHQLSYEALQPELRVGLFLRRAGRLRVDSAEGLHVVLYDCSVGHGDCSRCQTAMPQ 1038
Query: 865 LGHLCMWSDGCRLR-------GPLQPMAGTCPAPEIRAIEPLSGPLDGGTLLTIRGRNLG 917
G C+W +G R R G + +A CPAP I ++EPL+GP+DGGT +TIRG NLG
Sbjct: 1039 YG--CVWCEGERPRCVTREACGEAEAVATQCPAPLIHSVEPLTGPVDGGTRVTIRGSNLG 1096
Query: 918 RRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNASKEGK--SRDR 975
+ + DV V + GV C Y VS +VC+TG + ++G V G+ S
Sbjct: 1097 QHVQDVLGMVTVAGVPCAVDAQEYEVSSSLVCITGASGEEVAGATAVEVPGRGRGVSEHD 1156
Query: 976 FSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVG--SELQVLVNDTDPCTELMRTDTS-I 1032
F+Y P VHS+ P GP+AGGTR+T++G+ L G +++V+V D PC L + +
Sbjct: 1157 FAYQDPKVHSIFPARGPRAGGTRLTLNGSKLLTGRLEDIRVVVGD-QPCHLLPEQQSEQL 1215
Query: 1033 ACTMPEGALPAPVPVCVRFERRGCVHGNLT---FWYMQNPVITAISPRRSPVSGGRTITV 1089
C PA +PV V F G L F Y +P IT+ P +S +SGGR I V
Sbjct: 1216 RCETSPRPTPATLPVAVWF---GATERRLQRGQFKYTLDPNITSAGPTKSFLSGGREICV 1272
Query: 1090 AGERFHMVQNVSMAVHHIGR--------------------------------EPTLCKVL 1117
G+ +VQ + V + R EP C V
Sbjct: 1273 RGQNLDVVQTPRIRVTVVSRMLQPSQGLGRRRRVVPETACSLGPSCSSQQFEEP--CHVN 1330
Query: 1118 NSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQ 1177
+S LITC +P P D ++ D + L+P + L L NP+
Sbjct: 1331 SSQLITCRTPAL---PGLPEDPWVRVEFILDNLVFDFATLNPTPFSYEADPTLQPL-NPE 1386
Query: 1178 FSTAKREKWIKHHPGEPLTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSV- 1236
T +H PG + + E L + E IG C ++ ++ ++C
Sbjct: 1387 DPTMP----FRHKPGSVFS--VEGENLDLAMSKEEVVAMIGDGPCVVKTLTRHHLYCEPP 1440
Query: 1237 -------NESLGAAVGQLP-ITIQVGNFNQTIATLQLGGSE-----TAIIVSIVICSVLL 1283
+ +L A LP T+Q+GN ++ +Q G A V + + + LL
Sbjct: 1441 VEQPLPRHHALREAPDSLPEFTVQMGNLRFSLGHVQYDGESPGAFPVAAQVGLGVGTSLL 1500
Query: 1284 LLSVVAL-FVFCTKSRRAERYWQKTLLQMEEMESQIREEIRKGFAELQTDMTDLTKELNR 1342
L V+ + ++ KS++A R ++K +Q+E +ES +R+ +K F +L T+MTDLT +L
Sbjct: 1501 ALGVIIIVLMYRRKSKQALRDYKKVQIQLENLESSVRDRCKKEFTDLMTEMTDLTSDLLG 1560
Query: 1343 SQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQGSSQAQETHPLLGEWKIPESC 1402
S GIPFL+YK + R FFP PL + +PES
Sbjct: 1561 S-GIPFLDYKVYAERIFFP------------------------GHRESPLHRDLGVPESR 1595
Query: 1403 RPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRCSLASLLTIALHGKLEYYTSI 1462
RP +E+G+ S+LLN+K FL F+H LE Q+ F+ RDR +ASLLT+ALHGKLEY+T I
Sbjct: 1596 RPTVEQGLGQLSNLLNSKLFLTKFIHTLESQRTFSARDRAYVASLLTVALHGKLEYFTDI 1655
Query: 1463 MKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICMYSCLRETVGEPFFLLLCAIK 1522
++ LL DL+ AKNPKLMLRRTE+VVEK+LTNWMSIC+Y+ +R++VGEP ++L IK
Sbjct: 1656 LRTLLSDLVAQYVAKNPKLMLRRTETVVEKLLTNWMSICLYTFVRDSVGEPLYMLFRGIK 1715
Query: 1523 QQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSFQ---GCG-MDSLSVRAMDTD 1578
Q++KG +D++TGKA+YTLN+ LLRE++E +P LN G G + V+ +D D
Sbjct: 1716 HQVDKGPVDSVTGKAKYTLNDNRLLREDVEYRPLTLNALLAVGPGAGEAQGVPVKVLDCD 1775
Query: 1579 TLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASSTQSYILRDLDDTSVVEDGRKKLNT 1638
T++Q KEK+L+ K VP +Q P +D+EW + IL D D TS V+ ++LNT
Sbjct: 1776 TISQAKEKMLDQLYKGVPLTQRPDPRTLDVEWRSGVAGHLILSDEDVTSEVQGLWRRLNT 1835
Query: 1639 LAHYKIPEGASLAMS-------LIDKKDNTLGR----VKDLDTE--KYFHLVLPTDELAE 1685
L HYK+P+GA++A+ L + +D G ++D+D + +HLV P+DE E
Sbjct: 1836 LQHYKVPDGATVALVPCLTKHVLRENQDYVPGERTPMLEDVDEGGIRPWHLVKPSDE-PE 1894
Query: 1686 PKKSHRQS------HRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDKPPLAVKY 1739
P + R S R K +PEIYLTRLLS KGTLQKF+DDLF+ ILS P LAVKY
Sbjct: 1895 PPRPRRGSLRGGERERAKAIPEIYLTRLLSMKGTLQKFVDDLFQVILSTSRPVP-LAVKY 1953
Query: 1740 FFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHIDACLSVIA 1799
FFD L+EQA++ GISD DT+HIWKTNSLPLRFW+NI+KNPQFVFD+ +D++DA L VIA
Sbjct: 1954 FFDLLDEQAQQHGISDQDTIHIWKTNSLPLRFWINIIKNPQFVFDVQTSDNMDAVLLVIA 2013
Query: 1800 QAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQEMNAHLAE 1859
Q F+DAC+++D +LG+DSP NKLLYA++IP Y+++V+RYY I+ P S+QEMN+ LAE
Sbjct: 2014 QTFMDACTLADHKLGRDSPINKLLYARDIPRYKRMVERYYADIRQTVPASDQEMNSVLAE 2073
Query: 1860 ESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQHKFEQVVALMEDNI 1918
S Y + VA+ E+YKY +Y QI+ ALE + TA++ QL ++ +Q+ A +E+ +
Sbjct: 2074 LSWNYSGDLGARVALHELYKYINKYYDQIITALEEDGTAQKMQLGYRLQQIAAAVENKV 2132
Score = 251 bits (642), Expect = 4e-66
Identities = 222/742 (29%), Positives = 325/742 (43%), Gaps = 107/742 (14%)
Query: 54 PSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQAS 113
P+ T + A D +GT+YL A N L+QLS L LEA + GPV DS C P +P
Sbjct: 30 PNGTYLQHLARDPTSGTLYLGATNFLFQLS-PGLQLEATVSTGPVLDSRDCLPPVMPD-- 86
Query: 114 CEHPR-RLTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEP 172
E P+ + T+N N++L + PG +VVCGS++QG C+ RR G + + +R P P
Sbjct: 87 -ECPQAQPTNNPNQLLLVSPGA--LVVCGSVHQGVCEQRRLGQLEQLLLR------PERP 137
Query: 173 VTVFPSMLNVAANHPNASTVGLVLPPAAGAGGSRLL-VGATYTGYGSSFFPRNRSLEDHR 231
VAAN P STVGLV A G G LL VG YT G
Sbjct: 138 ----GDTQYVAANDPAVSTVGLV---AQGLAGEPLLFVGRGYTSRGVG------------ 178
Query: 232 FENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPP 291
P I R+L A S + K+ G ++ FVSAF
Sbjct: 179 -GGIPPITTRALWPPDPQAAF-------SYEETAKLAVGRLSEYSHHFVSAFAR------ 224
Query: 292 GAQSYAYLALNSEARAGDKESQA-RSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAG 350
GA +Y +L L + +A +S+A R+ ++R+CL + SY++L L C GG
Sbjct: 225 GASAY-FLFLRRDLQA---QSRAFRAYVSRVCL-------RDQHYYSYVELPLACEGGR- 272
Query: 351 RGDLYSRLVSVFPARER-------LFAVFE--------RPQGSPAARAAPAALCAFRFAD 395
Y + + A R LFA F RP + A + +ALCAF +
Sbjct: 273 ----YGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDE 328
Query: 396 VRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPA-CERKLN---IQLQPEQLD---CGAA 448
V R AC+ GT A E +N QL + LD CG+
Sbjct: 329 VDRLANRTRDACYTREG--------RAEDGTEVAYIEYDVNSDCAQLPVDTLDAYPCGSD 380
Query: 449 HLQHPLSILQPLKATPVFRAPG--LTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVV 506
H P++ PL+ATP+ PG LT+VAV + +T FLG G+L ++ L
Sbjct: 381 HTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGH 440
Query: 507 SRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYC 566
++ G V + FD +LY+MT + +V VA+C H C C+ D YC
Sbjct: 441 PYSTQSIQQGSAVSRDLTFDGTFE-HLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYC 499
Query: 567 GWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGS 626
GWC L RC+ + +C+ W + + C + + R+E + L +
Sbjct: 500 GWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMSPANISREETREVFLSVPDL 559
Query: 627 LPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLPRDQFPPFPPNQDHVTVEMSVR 686
P G +C +G + ++ A + G C + P P D+V+V + +R
Sbjct: 560 PPLWPGESYSCHFGEH-QSPALLTGSG-----VMCPSPDPSEAPVLPRGADYVSVSVELR 613
Query: 687 VNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCFWCSQQHSCVSNQSRCEASPNP 746
I K + + YDC ++ P C +C+S++W C WC QH C ++++ C+A P
Sbjct: 614 FGAVVIAKTSLSFYDCVAVTELRPSAQCQACVSSRWGCNWCVWQHLC-THKASCDAGPMV 672
Query: 747 TSPQDCPRTLLSPLAPVPTGGS 768
S Q L+SP P G S
Sbjct: 673 ASHQS---PLVSPDPPARGGPS 691
>gi|5032223 plexin C1 [Homo sapiens]
Length = 1568
Score = 539 bits (1388), Expect = e-152
Identities = 347/952 (36%), Positives = 521/952 (54%), Gaps = 94/952 (9%)
Query: 983 VHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTE------LMRTDTSIACTM 1036
+ S+EP G + + + G + S + +++ T C + + DT + ++
Sbjct: 664 IKSIEPQKVSTLGKSNVIVTGANFTRASNITMILKGTSTCDKDVIQVSHVLNDTHMKFSL 723
Query: 1037 PEGALPAPVPVCVRFERRGCVH-GNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFH 1095
P VC++F+ C G+L+ Y+ P + I P + +SGG+ IT+ G F
Sbjct: 724 PSSRKEMK-DVCIQFDGGNCSSVGSLS--YIALPHCSLIFPATTWISGGQNITMMGRNFD 780
Query: 1096 MVQNVSMAVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFFINGRAYADEVAVAEE 1155
++ N+ ++ H + + + +T +P +L ++ + + R V +
Sbjct: 781 VIDNLIIS-HELKGNINVSEYCVATYCGFLAP-SLKSSKVRTNVTVKLR-------VQDT 831
Query: 1156 LLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQDSLGLQSHEYRV 1215
LD Q Y +P+F+ + E + L + I KE D+ + + +
Sbjct: 832 YLDCGTLQ--------YREDPRFTGYRVESEVDTE----LEVKIQKENDNFNISKKDIEI 879
Query: 1216 KI-----GQVSCDIQIVSDR----IIHCSVNESLGAAV---GQLPITIQVGNFNQTIATL 1263
+ GQ++C + ++ I C + A+ + +++GN L
Sbjct: 880 TLFHGENGQLNCSFENITRNQDLTTILCKIKGIKTASTIANSSKKVRVKLGN-------L 932
Query: 1264 QLGGSETAIIVSIVICSVLLLLSVVALFVFCTKSR-RAERYWQKTLLQMEEMESQIREEI 1322
+L + ++ + VL +L V+ +F +R +++ +K Q+E +ES++R+EI
Sbjct: 933 ELYVEQESVPSTWYFLIVLPVLLVIVIFAAVGVTRHKSKELSRKQSQQLELLESELRKEI 992
Query: 1323 RKGFAELQTDMTDLTKELNRSQGIPFLEYKHFVTRTFFPKCSSLYEERYVLPSQTLNSQG 1382
R GFAELQ D D+ +PFL+YKHF RTFFP+ ++ N
Sbjct: 993 RDGFAELQMDKLDVVDSFGT---VPFLDYKHFALRTFFPESGGF---THIFTEDMHNRDA 1046
Query: 1383 SSQAQETHPLLGEWKIPESCRPNMEEGISLFSSLLNNKHFLIVFVHALEQQKDFAVRDRC 1442
+ + E ++ +L+ NK FL+ +H LE+QK+F+V+DRC
Sbjct: 1047 NDK---------------------NESLTALDALICNKSFLVTVIHTLEKQKNFSVKDRC 1085
Query: 1443 SLASLLTIALHGKLEYYTSIMKELLVDLIDASAAKNPKLMLRRTESVVEKMLTNWMSICM 1502
AS LTIAL KL Y TSI++ L DL++ + PKLMLRRTESVVEK+LTNWMS+C+
Sbjct: 1086 LFASFLTIALQTKLVYLTSILEVLTRDLMEQCSNMQPKLMLRRTESVVEKLLTNWMSVCL 1145
Query: 1503 YSCLRETVGEPFFLLLCAIKQQINKGSIDAITGKARYTLNEEWLLRENIEAKPRNLNVSF 1562
LRETVGEPF+LL+ + Q+INKG +D IT KA YTLNE+WLL + E LNV F
Sbjct: 1146 SGFLRETVGEPFYLLVTTLNQKINKGPVDVITCKALYTLNEDWLLWQVPEFSTVALNVVF 1205
Query: 1563 QGCGMD-------SLSVRAMDTDTLTQVKEKILEAFCKNVPYSQWPRAEDVDLEWFASST 1615
+ + ++SV +D DT+ Q KEKI +AF + ++ LE +
Sbjct: 1206 EKIPENESADVCRNISVNVLDCDTIGQAKEKIFQAFLSKNGSPYGLQLNEIGLELQMGTR 1265
Query: 1616 QSYILRDLDDTSVV-EDGRKKLNTLAHYKIPEGASLAMSLIDKKDNTLGRVKDLDTEKYF 1674
Q +L D+D +SV+ EDG KLNT+ HY+I G+++ + K N V+ D +
Sbjct: 1266 QKELL-DIDSSSVILEDGITKLNTIGHYEISNGSTI--KVFKKIANFTSDVEYSD--DHC 1320
Query: 1675 HLVLPTDELAE--PKKSHRQSHRKKVLPEIYLTRLLSTKGTLQKFLDDLFKAILSIREDK 1732
HL+LP E + K HR H+ KV E+YLT+LLSTK + L+ LF++I S+ +
Sbjct: 1321 HLILPDSEAFQDVQGKRHRGKHKFKV-KEMYLTKLLSTKVAIHSVLEKLFRSIWSLPNSR 1379
Query: 1733 PPLAVKYFFDFLEEQAEKRGISDPDTLHIWKTNSLPLRFWVNILKNPQFVFDIDKTDHID 1792
P A+KYFFDFL+ QAE + I+DPD +HIWKTNSLPLRFWVNILKNPQFVFDI KT HID
Sbjct: 1380 APFAIKYFFDFLDAQAENKKITDPDVVHIWKTNSLPLRFWVNILKNPQFVFDIKKTPHID 1439
Query: 1793 ACLSVIAQAFIDACSISDLQLGKDSPTNKLLYAKEIPEYRKIVQRYYKQIQDMTPLSEQE 1852
CLSVIAQAF+DA S+++ QLGK++PTNKLLYAK+IP Y++ V+ YYK I+D+ PLS E
Sbjct: 1440 GCLSVIAQAFMDAFSLTEQQLGKEAPTNKLLYAKDIPTYKEEVKSYYKAIRDLPPLSSSE 1499
Query: 1853 MNAHLAEESRKYQNEFNTNVAMAEIYKYAKRYRPQIMAALEANPTARRTQLQ 1904
M L +ES+K++NEFN VA+ EIYKY +Y +I+ LE Q Q
Sbjct: 1500 MEEFLTQESKKHENEFNEEVALTEIYKYIVKYFDEILNKLERERGLEEAQKQ 1551
Score = 132 bits (332), Expect = 3e-30
Identities = 190/748 (25%), Positives = 289/748 (38%), Gaps = 136/748 (18%)
Query: 21 PPFQTPPRCPVPLLLLLL-LGAARAGALEIQRRFPSPTPTNNFALDGAAGT----VYLAA 75
PP P P+PLL LL L A GA E P + A+ A + V++A+
Sbjct: 9 PPRPPRPAAPLPLLAYLLALAAPGRGADE-------PVWRSEQAIGAIAASQEDGVFVAS 61
Query: 76 VNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYNKILQLDPGQ- 134
+ L QL + SLE + + C P + A PR + +L G
Sbjct: 62 GSCLDQL---DYSLEHSLSRLYRDQAGNCTEP-VSLAPPARPRPGSSFSKLLLPYREGAA 117
Query: 135 ---GLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAANHPNAST 191
GL++ + +G C++R GN+S ++R + V + HP ST
Sbjct: 118 GLGGLLLTGWTFDRGACEVRPLGNLSRNSLR---------------NGTEVVSCHPQGST 162
Query: 192 VGLVLPPAAGAGGS-RLLVGATYTGYGSSFFPR-NRSLEDHRFENTPEIAIRSLDTRGDL 249
G+V AG L V ATY R N + DH + AI DT G
Sbjct: 163 AGVVY--RAGRNNRWYLAVAATYVLPEPETASRCNPAASDH------DTAIALKDTEG-- 212
Query: 250 AKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLALN-SEARAG 308
L T +L LK+ +GA H FV AFL G+ + Y N + A
Sbjct: 213 RSLATQELGR-----LKLCEGAGSLH---FVDAFLWN-----GSIYFPYYPYNYTSGAAT 259
Query: 309 DKESQARSLLARICLPHGAGGDAKKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPARERL 368
S AR + L G Q L C G G S+ A +
Sbjct: 260 GWPSMARIAQSTEVLFQG-------------QASLDCGHGHPDGRRLLLSSSLVEALDVW 306
Query: 369 FAVFERPQGSPAARAAPA--ALCAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQGT 426
VF G R +P ALC FR ++++A RA R + + A D
Sbjct: 307 AGVFSAAAGEGQERRSPTTTALCLFRMSEIQA--RAKRVSWDFKTAESHCKEGD------ 358
Query: 427 GPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGLTSVAVASVNNYTAVF 486
QPE++ QP+ ++ + + LTSV V N T +F
Sbjct: 359 ------------QPERV--------------QPIASSTLIHSD-LTSVYGTVVMNRTVLF 391
Query: 487 LGTVNGRLLKINLNESMQVVSRRVVTVAYGE-PVHHVMQFDPADSGYLYLMTSHQMARVK 545
LGT +G+LLK+ L E++ V+ E PV + + DP + Y+YL ++ R++
Sbjct: 392 LGTGDGQLLKVILGENLTSNCPEVIYEIKEETPVFYKLVPDPVKNIYIYLTAGKEVRRIR 451
Query: 546 VAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRCPAMTV 605
VA CN H +C +C+ A D +CGWC RCT Q DC +S W S G +CP + +
Sbjct: 452 VANCNKHKSCSECLTATDPHCGWCHSLQRCTFQGDCVHSENLENWLDISSGAKKCPKIQI 511
Query: 606 LPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIRTVARVPGPAFGHQIAYCNLLP 665
+ S +E + + + S S C N + + ++ C++
Sbjct: 512 IRSS----KEKTTVTM-----VGSFSPRHSKCMVKNVDSSRELCQNKSQPNRTCTCSIPT 562
Query: 666 RDQFPPFPPNQDHVTVEMSVRVNGRNIVKANFTIYDCSRTAQVYPHTACTSCLSAQWPCF 725
R + +D V + N+ F +CS + C +C+ + C
Sbjct: 563 RATY------KDVSVVNVMFSFGSWNL-SDRFNFTNCSSLKE------CPACV--ETGCA 607
Query: 726 WCSQQHSCVSNQSRCEASPNPTSPQDCP 753
WC C+ + C+ S + + CP
Sbjct: 608 WCKSARRCIHPFTACDPSDYERNQEQCP 635
>gi|153946393 macrophage stimulating 1 receptor precursor [Homo
sapiens]
Length = 1400
Score = 99.0 bits (245), Expect = 4e-20
Identities = 84/281 (29%), Positives = 125/281 (44%), Gaps = 40/281 (14%)
Query: 856 CSQCL------GREDLGHLCMWSDGCRLRGPLQPMAGTCPAPEIRAIEPLSGPLDGGTLL 909
C +CL G G++C C P CP P++ P SGPL G T L
Sbjct: 533 CGRCLRAWHFMGCGWCGNMCGQQKEC----PGSWQQDHCP-PKLTEFHPHSGPLRGSTRL 587
Query: 910 TIRGRNLGRRLSDVA----HGVWIGGVACEPLPD---------RYTVSEEIVCVTGP--- 953
T+ G N S + H V +G C PLP R EE C P
Sbjct: 588 TLCGSNFYLHPSGLVPEGTHQVTVGQSPCRPLPKDSSKLRPVPRKDFVEEFECELEPLGT 647
Query: 954 -APGPLSGVVTVNASKEGKS--------RDRFSYVLPLVHSLEPTMGPKAGGTRITIHGN 1004
A GP + +TV GK FS++ P++ +++P GP+AGGT +T+ G
Sbjct: 648 QAVGPTNVSLTVTNMPPGKHFRVDGTSVLRGFSFMEPVLIAVQPLFGPRAGGTCLTLEGQ 707
Query: 1005 DLHVGSELQVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFW 1064
L VG+ VLVN T+ C ++ + C P GA A VP+ ++ V G+ TF
Sbjct: 708 SLSVGTSRAVLVNGTE-CLLARVSEGQLLCATPPGATVASVPLSLQV-GGAQVPGSWTFQ 765
Query: 1065 YMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVH 1105
Y ++PV+ +ISP ++ IT+ G+ ++ ++ H
Sbjct: 766 YREDPVVLSISPNCGYINS--HITICGQHLTSAWHLVLSFH 804
Score = 58.9 bits (141), Expect = 5e-08
Identities = 137/613 (22%), Positives = 210/613 (34%), Gaps = 105/613 (17%)
Query: 27 PRCPVPLLLLLLLGAARAGALEIQ---------RRFPSPTPTNNFALDGAA--------- 68
P P LLLLLL A A + Q R F +F+ G
Sbjct: 5 PPLPQSFLLLLLLPAKPAAGEDWQCPRTPYAASRDFDVKYVVPSFSAGGLVQAMVTYEGD 64
Query: 69 ---GTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRRLTDNYN 125
V++A NRL+ L G +L A GP D P C P TD
Sbjct: 65 RNESAVFVAIRNRLHVL-GPDLKSVQSLATGPAGD-PGCQTCAACGPGPHGPPGDTDT-- 120
Query: 126 KILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSMLNVAAN 185
K+L LDP +V CGS QG C L AV A P +F + N +
Sbjct: 121 KVLVLDPALPALVSCGSSLQGRCFLHDL-EPQGTAVHL------AAPACLFSAHHNRPDD 173
Query: 186 HPN--ASTVGLVLPPAAGAGGSRLLVGATY-TGYGSSFFPRNRSLEDHRFENTPEIAIRS 242
P+ AS +G + S V ++ +SF PR+ ++IR
Sbjct: 174 CPDCVASPLGTRVTVVEQGQASYFYVASSLDAAVAASFSPRS-------------VSIRR 220
Query: 243 L--DTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFLHPSDPPPGAQSYAYLA 300
L D G + P +H + + ++H ++ Y
Sbjct: 221 LKADASGFAPGFVALSVLP--------------KHLVSYSIEYVHSFH----TGAFVYFL 262
Query: 301 LNSEARAGDKESQARSLLARICLPHGAGGDAKKLT------------------ESYIQLG 342
A D S + LAR+ GD ++L + Y L
Sbjct: 263 TVQPASVTDDPSALHTRLARLSATEPELGDYRELVLDCRFAPKRRRRGAPEGGQPYPVL- 321
Query: 343 LQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRA 402
+ A A G + +S+ +E LF VF + + +CAF + I
Sbjct: 322 -RVAHSAPVGAQLATELSIAEGQEVLFGVFVTGKDGGPGVGPNSVVCAFPIDLLDTLIDE 380
Query: 403 ARTACFVEPA-PDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLK 461
C P P + LD + C ++ C PL +
Sbjct: 381 GVERCCESPVHPGLRRGLDFFQSPS--FCPNPPGLEALSPNTSCR----HFPLLVSSSFS 434
Query: 462 ATPVFRA----PGLTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAYGE 517
+F +T++ V ++N T +GT++GR+L++ L S+ + V + G+
Sbjct: 435 RVDLFNGLLGPVQVTALYVTRLDNVTVAHMGTMDGRILQVELVRSLNYL-LYVSNFSLGD 493
Query: 518 PVHHVMQFDPADSGYLYLMTSHQMARVKV--AACNVHSTCGDCVGAADAY-CGWCALETR 574
V + +L + Q+ +V + C TCG C+ A CGWC
Sbjct: 494 SGQPVQRDVSRLGDHLLFASGDQVFQVPIQGPGCRHFLTCGRCLRAWHFMGCGWCG--NM 551
Query: 575 CTLQQDCTNSSQQ 587
C Q++C S QQ
Sbjct: 552 CGQQKECPGSWQQ 564
>gi|42741655 met proto-oncogene isoform b precursor [Homo sapiens]
Length = 1390
Score = 98.6 bits (244), Expect = 5e-20
Identities = 113/463 (24%), Positives = 195/463 (42%), Gaps = 47/463 (10%)
Query: 856 CSQCLGREDLGHLCMWSDGCRLRGPLQPMAGTCPA----PEIRAIEPLSGPLDGGTLLTI 911
CSQCL C W +R + ++GT P I + P S PL+GGT LTI
Sbjct: 526 CSQCLSAPPFVQ-CGWCHDKCVRSE-ECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTI 583
Query: 912 RGRNLGRRLSDVAH----GVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNAS 967
G + G R ++ V +G +C T++ + C GPA + + ++
Sbjct: 584 CGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNT-LKCTVGPAMNKHFNMSIIISN 642
Query: 968 KEGKSR-DRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELM 1026
G ++ FSYV P++ S+ P GP AGGT +T+ GN L+ G+ + + CT
Sbjct: 643 GHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGG-KTCTLKS 701
Query: 1027 RTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRT 1086
+++ + C P + V ++ + F Y ++P++ I P +S +SGG T
Sbjct: 702 VSNSILECYTPAQTISTEFAVKLKIDLAN--RETSIFSYREDPIVYEIHPTKSFISGGST 759
Query: 1087 ITVAGERFHMVQNVSMA--VHHIGREPTL-CKVLNSTLITCPSPGALSNASAPVDFFING 1143
IT G+ + V M VH GR T+ C+ +++ I C + +L + +
Sbjct: 760 ITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKA 819
Query: 1144 RAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREKWIKHHPGEPLTLVIHKEQ 1203
D + F L Y+ NP F ++ I E + + +
Sbjct: 820 FFMLDGIL-------------SKYFDLIYVHNPVFKPFEKPVMIS-MGNENVLEIKGNDI 865
Query: 1204 DSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVGQLPITIQVGNFNQTIATL 1263
D ++ +K+G SC+ + + C+V L +L I + Q I++
Sbjct: 866 DPEAVKGEV--LKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNI-----EWKQAISST 918
Query: 1264 QLG-------GSETAIIVSIVICSVLLLLSVVALFVFCTKSRR 1299
LG + T +I +V S LLL ++ F++ K ++
Sbjct: 919 VLGKVIVQPDQNFTGLIAGVVSISTALLL-LLGFFLWLKKRKQ 960
Score = 53.9 bits (128), Expect = 1e-06
Identities = 116/569 (20%), Positives = 202/569 (35%), Gaps = 87/569 (15%)
Query: 53 FPSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQA 112
F + TP N L ++L A N +Y L+ +L AE GPV + P C P
Sbjct: 46 FTAETPIQNVILH--EHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDC----FPCQ 99
Query: 113 SCEHPRRLT-----DNYNKILQLDP-GQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPA 166
C L+ DN N L +D ++ CGS+ +G CQ V A
Sbjct: 100 DCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRH-------VFPHNHTA 152
Query: 167 APPAEPVTVFPSMLNVAANHPN--ASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRN 224
+E +F + + P+ S +G + + VG T SS+FP
Sbjct: 153 DIQSEVHCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNT---INSSYFP-- 207
Query: 225 RSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFL 284
DH + I++R L D T D + + + ++ + + +V AF
Sbjct: 208 ----DHPLHS---ISVRRLKETKDGFMFLT------DQSYIDVLPEFRDSYPIKYVHAF- 253
Query: 285 HPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGG-------------DA 331
+ ++ Y L + D ++ ++ + G
Sbjct: 254 -------ESNNFIYF-LTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRK 305
Query: 332 KKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAF 391
K+ T+ + LQ A + G +R + + LF VF + + A +A+CAF
Sbjct: 306 KRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAF 365
Query: 392 RFADVRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQ 451
V V + GP E N L C A +
Sbjct: 366 PIKYVNDFFNKIVNKNNVR----------CLQHFYGPNHEHCFNRTLLRNSSGCEARRDE 415
Query: 452 HPLSILQPLKATPVFRAPG----LTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVS 507
+ L+ +F LTS++ + T LGT GR +++ ++ S +
Sbjct: 416 YRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRS-GPST 474
Query: 508 RRVVTVAYGEPV--HHVMQFDPADSGYLYLMTSHQMARVKV--AACNVHSTCGDCVGAAD 563
V + PV +++ +GY ++T ++ ++ + C +C C+ A
Sbjct: 475 PHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPP 534
Query: 564 -AYCGWCALETRCTLQQDCTNSSQQHFWT 591
CGWC +C ++C + + WT
Sbjct: 535 FVQCGWC--HDKCVRSEECLSGT----WT 557
>gi|157738647 plexin A4 isoform 3 [Homo sapiens]
Length = 492
Score = 88.2 bits (217), Expect = 7e-17
Identities = 109/463 (23%), Positives = 178/463 (38%), Gaps = 81/463 (17%)
Query: 60 NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRR 119
N+ +D G +YL AVNR+Y+LS ++L + GP D+P C+ P++ Q +C P
Sbjct: 52 NHLVVDERTGHIYLGAVNRIYKLS-SDLKVLVTHETGPDEDNPKCYPPRIVQ-TCNEPLT 109
Query: 120 LTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSM 179
T+N NK+L +D + ++ CGS+YQG C+L R ++ + + V S+
Sbjct: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
Query: 180 LNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIA 239
V ++ N +L + G F P I+
Sbjct: 170 FGVIVSYSNLD--------------DKLFIATAVDGKPEYF---------------PTIS 200
Query: 240 IRSLDTRGDLAKLFTFDLN----------PSD------DNILKIKQGAKEQHKLGFVSAF 283
R L + +F + + PSD D + G + + F++
Sbjct: 201 SRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLT-- 258
Query: 284 LHPS-DPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLG 342
L P PPG+ + KE S L R+C A ++ + G
Sbjct: 259 LQPEMVSPPGSTT--------------KEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSG 304
Query: 343 -----LQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVR 397
LQ A + G + R + V P + LF VF + Q +ALC F +
Sbjct: 305 VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIN 364
Query: 398 AAIRAARTACF-VEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSI 456
I+ +C+ E D+ + + P L I LD A PL +
Sbjct: 365 DRIKERLQSCYRGEGTLDLAWLKVKDI----PCSSALLTIDDNFCGLDMNA-----PLGV 415
Query: 457 LQPLKATPVFR--APGLTSVAVASVNNYTAVFLGTVNGRLLKI 497
++ PVF +TSV N++ F+GT +G+L K+
Sbjct: 416 SDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKKM 458
>gi|157738643 plexin A4 isoform 2 [Homo sapiens]
Length = 522
Score = 87.8 bits (216), Expect = 9e-17
Identities = 109/462 (23%), Positives = 177/462 (38%), Gaps = 81/462 (17%)
Query: 60 NNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQASCEHPRR 119
N+ +D G +YL AVNR+Y+LS ++L + GP D+P C+ P++ Q +C P
Sbjct: 52 NHLVVDERTGHIYLGAVNRIYKLS-SDLKVLVTHETGPDEDNPKCYPPRIVQ-TCNEPLT 109
Query: 120 LTDNYNKILQLDPGQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPAAPPAEPVTVFPSM 179
T+N NK+L +D + ++ CGS+YQG C+L R ++ + + V S+
Sbjct: 110 TTNNVNKMLLIDYKENRLIACGSLYQGICKLLRLEDLFKLGEPYHKKEHYLSGVNESGSV 169
Query: 180 LNVAANHPNASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRNRSLEDHRFENTPEIA 239
V ++ N +L + G F P I+
Sbjct: 170 FGVIVSYSNLD--------------DKLFIATAVDGKPEYF---------------PTIS 200
Query: 240 IRSLDTRGDLAKLFTFDLN----------PSD------DNILKIKQGAKEQHKLGFVSAF 283
R L + +F + + PSD D + G + + F++
Sbjct: 201 SRKLTKNSEADGMFAYVFHDEFVASMIKIPSDTFTIIPDFDIYYVYGFSSGNFVYFLT-- 258
Query: 284 LHPS-DPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTESYIQLG 342
L P PPG+ + KE S L R+C A ++ + G
Sbjct: 259 LQPEMVSPPGSTT--------------KEQVYTSKLVRLCKEDTAFNSYVEVPIGCERSG 304
Query: 343 -----LQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAFRFADVR 397
LQ A + G + R + V P + LF VF + Q +ALC F +
Sbjct: 305 VEYRLLQAAYLSKAGAVLGRTLGVHPDDDLLFTVFSKGQKRKMKSLDESALCIFILKQIN 364
Query: 398 AAIRAARTACF-VEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSI 456
I+ +C+ E D+ + + P L I LD A PL +
Sbjct: 365 DRIKERLQSCYRGEGTLDLAWLKVKDI----PCSSALLTIDDNFCGLDMNA-----PLGV 415
Query: 457 LQPLKATPVFR--APGLTSVAVASVNNYTAVFLGTVNGRLLK 496
++ PVF +TSV N++ F+GT +G+L K
Sbjct: 416 SDMVRGIPVFTEDRDRMTSVIAYVYKNHSLAFVGTKSGKLKK 457
>gi|188595716 met proto-oncogene isoform a precursor [Homo sapiens]
Length = 1408
Score = 87.4 bits (215), Expect = 1e-16
Identities = 113/481 (23%), Positives = 195/481 (40%), Gaps = 65/481 (13%)
Query: 856 CSQCLGREDLGHLCMWSDGCRLRGPLQPMAGTCPA----PEIRAIEPLSGPLDGGTLLTI 911
CSQCL C W +R + ++GT P I + P S PL+GGT LTI
Sbjct: 526 CSQCLSAPPFVQ-CGWCHDKCVRSE-ECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTI 583
Query: 912 RGRNLGRRLSDVAH----GVWIGGVACEPLPDRYTVSEEIVCVTGPAPGPLSGVVTVNAS 967
G + G R ++ V +G +C T++ + C GPA + + ++
Sbjct: 584 CGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNT-LKCTVGPAMNKHFNMSIIISN 642
Query: 968 KEGKSR-DRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELM 1026
G ++ FSYV P++ S+ P GP AGGT +T+ GN L+ G+ + + CT
Sbjct: 643 GHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGG-KTCTLKS 701
Query: 1027 RTDTSIACTMPEGALPAPVPVCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPV----- 1081
+++ + C P + V ++ + F Y ++P++ I P +S +
Sbjct: 702 VSNSILECYTPAQTISTEFAVKLKIDLAN--RETSIFSYREDPIVYEIHPTKSFISTWWK 759
Query: 1082 -------------SGGRTITVAGERFHMVQNVSMA--VHHIGREPTL-CKVLNSTLITCP 1125
SGG TIT G+ + V M VH GR T+ C+ +++ I C
Sbjct: 760 EPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICC 819
Query: 1126 SPGALSNASAPVDFFINGRAYADEVAVAEELLDPEEAQRGSRFRLDYLPNPQFSTAKREK 1185
+ +L + + D + F L Y+ NP F ++
Sbjct: 820 TTPSLQQLNLQLPLKTKAFFMLDGIL-------------SKYFDLIYVHNPVFKPFEKPV 866
Query: 1186 WIKHHPGEPLTLVIHKEQDSLGLQSHEYRVKIGQVSCDIQIVSDRIIHCSVNESLGAAVG 1245
I E + + + D ++ +K+G SC+ + + C+V L
Sbjct: 867 MIS-MGNENVLEIKGNDIDPEAVKGEV--LKVGNKSCENIHLHSEAVLCTVPNDLLKLNS 923
Query: 1246 QLPITIQVGNFNQTIATLQLG-------GSETAIIVSIVICSVLLLLSVVALFVFCTKSR 1298
+L I + Q I++ LG + T +I +V S LLL ++ F++ K +
Sbjct: 924 ELNI-----EWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISTALLL-LLGFFLWLKKRK 977
Query: 1299 R 1299
+
Sbjct: 978 Q 978
Score = 53.9 bits (128), Expect = 1e-06
Identities = 116/569 (20%), Positives = 202/569 (35%), Gaps = 87/569 (15%)
Query: 53 FPSPTPTNNFALDGAAGTVYLAAVNRLYQLSGANLSLEAEAAVGPVPDSPLCHAPQLPQA 112
F + TP N L ++L A N +Y L+ +L AE GPV + P C P
Sbjct: 46 FTAETPIQNVILH--EHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDC----FPCQ 99
Query: 113 SCEHPRRLT-----DNYNKILQLDP-GQGLVVVCGSIYQGFCQLRRRGNISAVAVRFPPA 166
C L+ DN N L +D ++ CGS+ +G CQ V A
Sbjct: 100 DCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRH-------VFPHNHTA 152
Query: 167 APPAEPVTVFPSMLNVAANHPN--ASTVGLVLPPAAGAGGSRLLVGATYTGYGSSFFPRN 224
+E +F + + P+ S +G + + VG T SS+FP
Sbjct: 153 DIQSEVHCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNT---INSSYFP-- 207
Query: 225 RSLEDHRFENTPEIAIRSLDTRGDLAKLFTFDLNPSDDNILKIKQGAKEQHKLGFVSAFL 284
DH + I++R L D T D + + + ++ + + +V AF
Sbjct: 208 ----DHPLHS---ISVRRLKETKDGFMFLT------DQSYIDVLPEFRDSYPIKYVHAF- 253
Query: 285 HPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGG-------------DA 331
+ ++ Y L + D ++ ++ + G
Sbjct: 254 -------ESNNFIYF-LTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRK 305
Query: 332 KKLTESYIQLGLQCAGGAGRGDLYSRLVSVFPARERLFAVFERPQGSPAARAAPAALCAF 391
K+ T+ + LQ A + G +R + + LF VF + + A +A+CAF
Sbjct: 306 KRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAF 365
Query: 392 RFADVRAAIRAARTACFVEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQ 451
V V + GP E N L C A +
Sbjct: 366 PIKYVNDFFNKIVNKNNVR----------CLQHFYGPNHEHCFNRTLLRNSSGCEARRDE 415
Query: 452 HPLSILQPLKATPVFRAPG----LTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVS 507
+ L+ +F LTS++ + T LGT GR +++ ++ S +
Sbjct: 416 YRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRS-GPST 474
Query: 508 RRVVTVAYGEPV--HHVMQFDPADSGYLYLMTSHQMARVKV--AACNVHSTCGDCVGAAD 563
V + PV +++ +GY ++T ++ ++ + C +C C+ A
Sbjct: 475 PHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPP 534
Query: 564 -AYCGWCALETRCTLQQDCTNSSQQHFWT 591
CGWC +C ++C + + WT
Sbjct: 535 FVQCGWC--HDKCVRSEECLSGT----WT 557
>gi|126116589 fibrocystin L [Homo sapiens]
Length = 4243
Score = 65.9 bits (159), Expect = 4e-10
Identities = 69/261 (26%), Positives = 113/261 (43%), Gaps = 21/261 (8%)
Query: 891 PEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCV 950
P +R I P GP GT + I G N G + +++ V I + C +V + C+
Sbjct: 1916 PFLRGIIPSRGP--PGTEIEITGSNFGFEILEIS--VMINNIQCNVTMANDSV---VQCI 1968
Query: 951 TGPAPGPLSGVVTVNASKEGKSRDRFSYVLPL-VHSLEPTMGPKAGGTRITIHGNDLHVG 1009
G G V+ + +K G + + PL + ++ P+ G GG +T+ G +
Sbjct: 1969 VGDHAGGTFPVMMHHKTK-GSAMSTVVFEYPLNIQNINPSQGSFGGGQTMTVTGTGFNPQ 2027
Query: 1010 SELQVLVNDTDPCTELMRTD-TSIACTMPE----GALPAPVPVCVRFERRGCVHGNLTFW 1064
+ + +LV ++ + +R+D T++ C +P GA A V + T+
Sbjct: 2028 NSI-ILVCGSECAIDRLRSDYTTLLCEIPSNNGTGAEQACEVSVVNGKDLSQSMTPFTYA 2086
Query: 1065 YMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKV--LNSTLI 1122
P+ITA+SP+R +GG +TV G F + +M HI C V N T I
Sbjct: 2087 VSLTPLITAVSPKRGSTAGGTRLTVVGSGF----SENMEDVHITIAEAKCDVEYSNKTHI 2142
Query: 1123 TCPSPGALSNASAPVDFFING 1143
C + + APV I G
Sbjct: 2143 ICMTDAHTLSGWAPVCVHIRG 2163
Score = 53.1 bits (126), Expect = 3e-06
Identities = 63/247 (25%), Positives = 94/247 (38%), Gaps = 24/247 (9%)
Query: 886 GTCPAPEIRAIEP-----LSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDR 940
G C + +I P + G + I G LG L D+A V+IG +
Sbjct: 1737 GNCTFSYLESITPYITGVFPNSVIGSVKVLIEGEGLGTVLEDIA--VFIGNQQFRAIEVN 1794
Query: 941 YTVSEEIVCVTGPAPGPLSGVVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGGTRIT 1000
I + P P V V SK G + + P V SL PT G GGT +
Sbjct: 1795 ---ENNITALVTPLPVGHHSVSVVVGSK-GLALGNLTVSSPPVASLSPTSGSIGGGTTLV 1850
Query: 1001 IHGNDLHVGSELQVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHGN 1060
I GN + G+ V + D +PC + + C P G V V+ +
Sbjct: 1851 ITGNGFYPGN-TTVTIGD-EPCQIISINPNEVYCRTPAGTTGM---VDVKIFVNTIAYPP 1905
Query: 1061 LTFWYM--QNPVITAISPRRSPVSGGRTITVAGERFHM-VQNVSMAVHHIGREPTLCKVL 1117
L F Y P + I P R P G I + G F + +S+ +++I T+
Sbjct: 1906 LLFTYALEDTPFLRGIIPSRGP--PGTEIEITGSNFGFEILEISVMINNIQCNVTMA--- 1960
Query: 1118 NSTLITC 1124
N +++ C
Sbjct: 1961 NDSVVQC 1967
Score = 52.8 bits (125), Expect = 3e-06
Identities = 65/245 (26%), Positives = 97/245 (39%), Gaps = 22/245 (8%)
Query: 891 PEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCV 950
P + AI P G + GT+LTI G A V +G V C L +E+ C
Sbjct: 1067 PLVLAISPSQGSYEEGTILTIVGSGFS---PSSAVTVSVGPVGCSLLS---VDEKELKCQ 1120
Query: 951 -----TGPAPGPLSGVVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGGTRITIHGND 1005
G AP +S A G F Y + H + P G AGGT +T+ G
Sbjct: 1121 ILNGSAGHAPVAVSMADVGLAQNVGGEEFYFVYQSQISH-IWPDSGSIAGGTLLTLSGFG 1179
Query: 1006 LHVGSELQVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFER-RGCVHGNLTFW 1064
+ S++ V + C + I C P+ V + V + ++
Sbjct: 1180 FNENSKVLV---GNETCNVIEGDLNRITCRTPKKT-EGTVDISVTTNGFQATARDAFSYN 1235
Query: 1065 YMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVL--NSTLI 1122
+Q P+IT SP+ + G +T+ G F +MAV+ G+ C++L N T I
Sbjct: 1236 CLQTPIITDFSPKVRTILGEVNLTIKGYNFGNELTQNMAVYVGGK---TCQILHWNFTDI 1292
Query: 1123 TCPSP 1127
C P
Sbjct: 1293 RCLLP 1297
Score = 46.2 bits (108), Expect = 3e-04
Identities = 54/219 (24%), Positives = 86/219 (39%), Gaps = 29/219 (13%)
Query: 892 EIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVT 951
+I I P SG + GGTLLT+ G V +G C + ++ +T
Sbjct: 1156 QISHIWPDSGSIAGGTLLTLSGFGFNENSK-----VLVGNETCN------VIEGDLNRIT 1204
Query: 952 GPAPGPLSGVVTVNASKEG---KSRDRFSY---VLPLVHSLEPTMGPKAGGTRITIHGND 1005
P G V ++ + G +RD FSY P++ P + G +TI G +
Sbjct: 1205 CRTPKKTEGTVDISVTTNGFQATARDAFSYNCLQTPIITDFSPKVRTILGEVNLTIKGYN 1264
Query: 1006 LHVGSEL---QVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRGCVHG--- 1059
G+EL + C L T I C +P+ + P + V G
Sbjct: 1265 F--GNELTQNMAVYVGGKTCQILHWNFTDIRCLLPKLS-PGKHDIYVEVRNWGFASTRDK 1321
Query: 1060 -NLTFWYMQNPVITAISPRRSPVSGGRTITVAGERFHMV 1097
N + Y+ +T++ P+R + GG IT+ G F +
Sbjct: 1322 LNSSIQYVLE--VTSMFPQRGSLFGGTEITIRGFGFSTI 1358
Score = 45.1 bits (105), Expect = 7e-04
Identities = 42/155 (27%), Positives = 67/155 (43%), Gaps = 13/155 (8%)
Query: 977 SYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTSIACTM 1036
S + PLV ++ P+ G GT +TI G+ S + V V C+ L + + C +
Sbjct: 1063 SNITPLVLAISPSQGSYEEGTILTIVGSGFSPSSAVTVSVGPVG-CSLLSVDEKELKCQI 1121
Query: 1037 PEGALPAPVPVCVRFERRGCVH--GNLTFWYMQNPVITAISPRRSPVSGGRTITVAGERF 1094
G+ PV V G G F+++ I+ I P ++GG +T++G F
Sbjct: 1122 LNGS-AGHAPVAVSMADVGLAQNVGGEEFYFVYQSQISHIWPDSGSIAGGTLLTLSGFGF 1180
Query: 1095 HMVQNVSMAVHHIGREPTLCKVLNSTL--ITCPSP 1127
+ V +G E C V+ L ITC +P
Sbjct: 1181 NENSKVL-----VGNE--TCNVIEGDLNRITCRTP 1208
Score = 44.7 bits (104), Expect = 9e-04
Identities = 58/219 (26%), Positives = 87/219 (39%), Gaps = 23/219 (10%)
Query: 887 TCPAPEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEE 946
+C +P I I P +G ++ L+TI G A+ V IG C + +
Sbjct: 1562 SCFSPSISNITPSTGTVN--ELITIIGHGFSNL--PWANKVTIGSYPCVV---EESSEDS 1614
Query: 947 IVCVTGPAPGPLSGV---VTVNASKEGKSR-------DRFSYVLPLVHSLEPTMGPKAGG 996
I C P G+ VT+ G + DR +LP + + P G G
Sbjct: 1615 ITCHIDPQNSMDVGIRETVTLTVYNLGTAINTLSNEFDRRFVLLPNIDLVLPNAGSTTGM 1674
Query: 997 TRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTSIAC-TMPEGALPAPVPVCVRFERRG 1055
T +TI G+ V S ++ PC L T+I C T P V + +
Sbjct: 1675 TSVTIKGSGFAVSSAGVKVLMGHFPCKVLSVNYTAIECETSPAAQQLVDVDLLIHGVPAQ 1734
Query: 1056 CVHGNLTFWYMQN--PVITAISPRRSPVSGGRTITVAGE 1092
C GN TF Y+++ P IT + P + V G + + GE
Sbjct: 1735 C-QGNCTFSYLESITPYITGVFP--NSVIGSVKVLIEGE 1770
Score = 34.3 bits (77), Expect = 1.2
Identities = 25/70 (35%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 892 EIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVT 951
E+ I P G + GGT LTI GR + +D V +GG C+ L I C T
Sbjct: 271 EVTMIFPSQGSIRGGTTLTISGRFFDQ--TDFPVRVLVGGEPCDIL---NVTENSICCKT 325
Query: 952 GPAPGPLSGV 961
P P L V
Sbjct: 326 PPKPHILKTV 335
Score = 32.0 bits (71), Expect = 6.0
Identities = 37/167 (22%), Positives = 63/167 (37%), Gaps = 29/167 (17%)
Query: 977 SYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTD--PCTELMRTDTSIAC 1034
S ++P V + P G G TR+TI G ++ V++ + +L+ + SI C
Sbjct: 27 SQIIPKVTEIIPKYGSINGATRLTIRGEGFSQANQFNYGVDNAELGNSVQLISSFQSITC 86
Query: 1035 -----------------TMPEGALPAPVPV-CVRFERRGCVHGNLTFW-------YMQNP 1069
MPE + V V V G++ W + P
Sbjct: 87 DVEKDASHSTQITCYTRAMPEDSYTVRVSVDGVPVTENNTCKGHINSWECTFNAKSFRTP 146
Query: 1070 VITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKV 1116
I +I+P + G IT+ G F V ++A+ G+ + +V
Sbjct: 147 TIRSITPLSG--TPGTLITIQGRIFTDVYGSNIALSSNGKNVRILRV 191
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 60.8 bits (146), Expect = 1e-08
Identities = 68/261 (26%), Positives = 110/261 (42%), Gaps = 43/261 (16%)
Query: 426 TGPACERKLN--IQLQPEQLDCGAAH------LQHPLSILQP---LKATPVFRAPGLTSV 474
T A ERK+N +QL L+ H ++ + +LQP + V R PGL
Sbjct: 401 TNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-- 458
Query: 475 AVASVNNYTAVFLGTVNGRLLK-------INLNESMQVVSRRVVTVAYGEPVHHVMQFDP 527
+ Y +FLGT +GRL K +++ E +Q+ S G+PV +++
Sbjct: 459 -----HTYDVLFLGTGDGRLHKAVSVGPRVHIIEELQIFSS-------GQPVQNLLL--D 504
Query: 528 ADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQ 587
G LY + + +V +A C+++ +CGDC+ A D YC W + C
Sbjct: 505 THRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSG--SSCKHVSLYQPQLAT 562
Query: 588 HFWTSASEGPSR---CPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIR 644
W EG S C A +V+ E P +Q + + +AC +N+
Sbjct: 563 RPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTVN----TLACPLLSNLA 618
Query: 645 TVARVPGPAFGHQIAYCNLLP 665
T + A + A C++LP
Sbjct: 619 TRLWLRNGAPVNASASCHVLP 639
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 60.8 bits (146), Expect = 1e-08
Identities = 68/261 (26%), Positives = 110/261 (42%), Gaps = 43/261 (16%)
Query: 426 TGPACERKLN--IQLQPEQLDCGAAH------LQHPLSILQP---LKATPVFRAPGLTSV 474
T A ERK+N +QL L+ H ++ + +LQP + V R PGL
Sbjct: 401 TNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-- 458
Query: 475 AVASVNNYTAVFLGTVNGRLLK-------INLNESMQVVSRRVVTVAYGEPVHHVMQFDP 527
+ Y +FLGT +GRL K +++ E +Q+ S G+PV +++
Sbjct: 459 -----HTYDVLFLGTGDGRLHKAVSVGPRVHIIEELQIFSS-------GQPVQNLLL--D 504
Query: 528 ADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQ 587
G LY + + +V +A C+++ +CGDC+ A D YC W + C
Sbjct: 505 THRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSG--SSCKHVSLYQPQLAT 562
Query: 588 HFWTSASEGPSR---CPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGMEMACDYGNNIR 644
W EG S C A +V+ E P +Q + + +AC +N+
Sbjct: 563 RPWIQDIEGASAKDLCSASSVVSPSFVPTGEKPCEQVQFQPNTVN----TLACPLLSNLA 618
Query: 645 TVARVPGPAFGHQIAYCNLLP 665
T + A + A C++LP
Sbjct: 619 TRLWLRNGAPVNASASCHVLP 639
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 57.0 bits (136), Expect = 2e-07
Identities = 74/324 (22%), Positives = 126/324 (38%), Gaps = 27/324 (8%)
Query: 296 YAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLT-ESYIQLGLQCAGGAGRGDL 354
+AY L A D S +AR+C G + T ++++ L C+
Sbjct: 296 FAYFFLRENAVEHDCGRTVYSRVARVCKNDVGGRFLLEDTWTTFMKARLNCSRPGEVPFY 355
Query: 355 YSRLVSVF--PARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAA------RTA 406
Y+ L S F P ++ ++ VF S AA +A+CAF + + A A
Sbjct: 356 YNELQSAFHLPEQDLIYGVFTTNVNSIAA----SAVCAFNLSAISQAFNGPFRYQENPRA 411
Query: 407 CFVEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVF 466
++ A + + TGP E LQ Q + P++ + V
Sbjct: 412 AWLPIANPIPNFQCGTLPETGPN-ENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVR 470
Query: 467 RAPGLTSVAVASVNNYTAVFLGTVNGRLLKINLNESMQV-----VSRRVVTVAYGEPVHH 521
+ + + A Y +++GT +G +LK S + V+ EP+
Sbjct: 471 FSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLHGCYLEELHVLPPGRREPLRS 530
Query: 522 VMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDC 581
+ A + L++ + RV + C + + G C+GA D YCGW + RC+ +D
Sbjct: 531 LRILHSARA--LFVGLRDGVLRVPLERCAAYRSQGACLGARDPYCGWDGKQQRCSTLEDS 588
Query: 582 TNSSQQHFWTSASEGPSRCPAMTV 605
+N S WT + + CP V
Sbjct: 589 SNMS---LWT---QNITACPVRNV 606
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 52.4 bits (124), Expect = 4e-06
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 3/127 (2%)
Query: 482 YTAVFLGTVNGRLLK-INLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQ 540
Y +F+ T G L K I+L ++ ++ + + EPV ++ + ++Y ++
Sbjct: 436 YDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDF-EPVQTLLLSSKKGNRFVYAGSNSG 494
Query: 541 MARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRC 600
+ + +A C H TC DCV A D YC W C T S + S S C
Sbjct: 495 VVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQ-TESPSRGLIQEMSGDASVC 553
Query: 601 PAMTVLP 607
PA + P
Sbjct: 554 PASSPKP 560
>gi|126131104 fibrocystin isoform 2 [Homo sapiens]
Length = 3396
Score = 51.6 bits (122), Expect = 7e-06
Identities = 67/278 (24%), Positives = 106/278 (38%), Gaps = 15/278 (5%)
Query: 891 PEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLP-DRYTVSEEIVC 949
P I AI P G GGT+LT+RG L R V + G C L +T+ ++
Sbjct: 1389 PRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDL-SGPFTCVILSLGDHTILCQVSL 1447
Query: 950 VTGPAPG---PLSGVVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGG--TRITIHGN 1004
P PG L+ V VN + ++ + + G T + I G
Sbjct: 1448 EGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLTTVLIRGQ 1507
Query: 1005 DL-HVGSELQVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRG-CVHGNLT 1062
L E V V+D PC + + C + A P P + V + R G GN++
Sbjct: 1508 RLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLA-PGPHYLSVFYTRNGYACSGNVS 1566
Query: 1063 FWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLI 1122
+ P + P+ + GG +T+ G S+ +I ++ L + + LI
Sbjct: 1567 RHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSV---YIDQQTCLTVNIGAELI 1623
Query: 1123 TCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPE 1160
C P N S ++ ++G Y V + PE
Sbjct: 1624 RCIVP--TGNGSVALEIEVDGLWYHIGVIGYNKAFTPE 1659
Score = 48.9 bits (115), Expect = 5e-05
Identities = 77/281 (27%), Positives = 121/281 (43%), Gaps = 39/281 (13%)
Query: 892 EIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVT 951
E+ +IEP G L GGT+L+I G R + V V +G +C+ + I C T
Sbjct: 1197 EVFSIEPCCGSLLGGTILSISGIGFSRDPALV--WVLVGNRSCDIV---NLTEASIWCET 1251
Query: 952 GPAPG-PLSGVVTVNASKEGKSRDRFSYVLP----------LVHSLEPTMGPKAGGTRIT 1000
PAP P +G TV A+ E + +RF P ++ T A IT
Sbjct: 1252 LPAPQIPDAGAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEIT 1311
Query: 1001 IHGNDLHVG----SELQVLVN--DTDPCTELMRTDTSIA-CTMPEGALPAPV-PVCVRFE 1052
LHVG S +L+ + D T+ + + S++ C++P +L A + P+ VR +
Sbjct: 1312 NSSLSLHVGGSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQK 1371
Query: 1053 RRGCVHGNLTF-WYMQNPVITAISPRRSPVSGGRTITVAG---------ERFHMVQNVSM 1102
+ G + ++ + P I AI P + GG +TV G R + +
Sbjct: 1372 QMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTC 1431
Query: 1103 AVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFFING 1143
+ +G LC+V +L P PGA + S V +NG
Sbjct: 1432 VILSLGDHTILCQV---SLEGDPLPGA--SFSLNVTVLVNG 1467
Score = 37.4 bits (85), Expect = 0.14
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 7/136 (5%)
Query: 974 DRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTS-- 1031
D F V P + +EP+ GG TI G+ L + +++ + C + T S
Sbjct: 1012 DLFLNVKPRLDMVEPSRAADIGGLWATIRGSSLE---GVSLILFGSYSCAINVATSNSSR 1068
Query: 1032 IACTMPEGALPAPVP--VCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITV 1089
I C +P + +R + + T+ NPVI +S S ++GG T+ +
Sbjct: 1069 IQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVI 1128
Query: 1090 AGERFHMVQNVSMAVH 1105
R ++ + VH
Sbjct: 1129 GVARLMNYTDLDVEVH 1144
>gi|126131102 fibrocystin isoform 1 [Homo sapiens]
Length = 4074
Score = 51.6 bits (122), Expect = 7e-06
Identities = 67/278 (24%), Positives = 106/278 (38%), Gaps = 15/278 (5%)
Query: 891 PEIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLP-DRYTVSEEIVC 949
P I AI P G GGT+LT+RG L R V + G C L +T+ ++
Sbjct: 1389 PRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDL-SGPFTCVILSLGDHTILCQVSL 1447
Query: 950 VTGPAPG---PLSGVVTVNASKEGKSRDRFSYVLPLVHSLEPTMGPKAGG--TRITIHGN 1004
P PG L+ V VN + ++ + + G T + I G
Sbjct: 1448 EGDPLPGASFSLNVTVLVNGLTSECQGNCTLFIREEASPVMDALSTNTSGSLTTVLIRGQ 1507
Query: 1005 DL-HVGSELQVLVNDTDPCTELMRTDTSIACTMPEGALPAPVPVCVRFERRG-CVHGNLT 1062
L E V V+D PC + + C + A P P + V + R G GN++
Sbjct: 1508 RLATTADEPMVFVDDQLPCNVTFFNASHVVCQTRDLA-PGPHYLSVFYTRNGYACSGNVS 1566
Query: 1063 FWYMQNPVITAISPRRSPVSGGRTITVAGERFHMVQNVSMAVHHIGREPTLCKVLNSTLI 1122
+ P + P+ + GG +T+ G S+ +I ++ L + + LI
Sbjct: 1567 RHFYIMPQVFHYFPKNFSLHGGSLLTIEGTGLRGQNTTSV---YIDQQTCLTVNIGAELI 1623
Query: 1123 TCPSPGALSNASAPVDFFINGRAYADEVAVAEELLDPE 1160
C P N S ++ ++G Y V + PE
Sbjct: 1624 RCIVP--TGNGSVALEIEVDGLWYHIGVIGYNKAFTPE 1659
Score = 48.9 bits (115), Expect = 5e-05
Identities = 77/281 (27%), Positives = 121/281 (43%), Gaps = 39/281 (13%)
Query: 892 EIRAIEPLSGPLDGGTLLTIRGRNLGRRLSDVAHGVWIGGVACEPLPDRYTVSEEIVCVT 951
E+ +IEP G L GGT+L+I G R + V V +G +C+ + I C T
Sbjct: 1197 EVFSIEPCCGSLLGGTILSISGIGFSRDPALV--WVLVGNRSCDIV---NLTEASIWCET 1251
Query: 952 GPAPG-PLSGVVTVNASKEGKSRDRFSYVLP----------LVHSLEPTMGPKAGGTRIT 1000
PAP P +G TV A+ E + +RF P ++ T A IT
Sbjct: 1252 LPAPQIPDAGAPTVPAAVEVWAGNRFFARGPSPSLVGKGFTFMYEAAATPVVTAMQGEIT 1311
Query: 1001 IHGNDLHVG----SELQVLVN--DTDPCTELMRTDTSIA-CTMPEGALPAPV-PVCVRFE 1052
LHVG S +L+ + D T+ + + S++ C++P +L A + P+ VR +
Sbjct: 1312 NSSLSLHVGGSNLSNSVILLGNLNCDVETQSFQGNVSLSGCSIPLHSLEAGIYPLQVRQK 1371
Query: 1053 RRGCVHGNLTF-WYMQNPVITAISPRRSPVSGGRTITVAG---------ERFHMVQNVSM 1102
+ G + ++ + P I AI P + GG +TV G R + +
Sbjct: 1372 QMGFANMSVVLQQFAVMPRIMAIFPSQGSACGGTILTVRGLLLNSRRRSVRVDLSGPFTC 1431
Query: 1103 AVHHIGREPTLCKVLNSTLITCPSPGALSNASAPVDFFING 1143
+ +G LC+V +L P PGA + S V +NG
Sbjct: 1432 VILSLGDHTILCQV---SLEGDPLPGA--SFSLNVTVLVNG 1467
Score = 37.4 bits (85), Expect = 0.14
Identities = 32/136 (23%), Positives = 56/136 (41%), Gaps = 7/136 (5%)
Query: 974 DRFSYVLPLVHSLEPTMGPKAGGTRITIHGNDLHVGSELQVLVNDTDPCTELMRTDTS-- 1031
D F V P + +EP+ GG TI G+ L + +++ + C + T S
Sbjct: 1012 DLFLNVKPRLDMVEPSRAADIGGLWATIRGSSLE---GVSLILFGSYSCAINVATSNSSR 1068
Query: 1032 IACTMPEGALPAPVP--VCVRFERRGCVHGNLTFWYMQNPVITAISPRRSPVSGGRTITV 1089
I C +P + +R + + T+ NPVI +S S ++GG T+ +
Sbjct: 1069 IQCKVPPRGKDGRIVNVTVIRGDYSAVLPRAFTYVSSLNPVIVTLSRNISNIAGGETLVI 1128
Query: 1090 AGERFHMVQNVSMAVH 1105
R ++ + VH
Sbjct: 1129 GVARLMNYTDLDVEVH 1144
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 50.1 bits (118), Expect = 2e-05
Identities = 71/329 (21%), Positives = 123/329 (37%), Gaps = 44/329 (13%)
Query: 295 SYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLT-ESYIQLGLQCAGGAGRGD 353
++ Y A D S AR+C G + T ++++ L C+
Sbjct: 227 NFTYFFFRENAVEHDCGKTVFSRAARVCKNDIGGRFLLEDTWTTFMKARLNCSRPGEVPF 286
Query: 354 LYSRLVSVF--PARERLFAVFERPQGSPAARAAPAALCAFRFADVRAAIRA-------AR 404
Y+ L S F P + ++ +F S AA +A+C F + + A +R
Sbjct: 287 YYNELQSTFFLPELDLIYGIFTTNVNSIAA----SAVCVFNLSAIAQAFSGPFKYQENSR 342
Query: 405 TACFVEPAPDVVAVLDSVVQGTGPACERKLNIQLQPEQL-DCGAAHLQHPLSILQPLKAT 463
+A P P+ +V QG L + L L D L H ++QP+
Sbjct: 343 SAWLPYPNPNPHFQCGTVDQG--------LYVNLTERNLQDAQKFILMH--EVVQPVTTV 392
Query: 464 PVFRAPG--LTSVAVASVNNYTA----VFLGTVNGRLLKINL-----NESMQVVSRRVVT 512
P F + VAV V A ++L T G + K+ + + S + +
Sbjct: 393 PSFMEDNSRFSHVAVDVVQGREALVHIIYLATDYGTIKKVRVPLNQTSSSCLLEEIELFP 452
Query: 513 VAYGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALE 572
EP+ + L++ + ++ + C + T C+GA D YCGW +
Sbjct: 453 ERRREPIRSLQILH--SQSVLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVM 510
Query: 573 TRCTLQQDCTNSSQQHFWTSASEGPSRCP 601
+CT ++ + +Q W + S CP
Sbjct: 511 KKCTSLEESLSMTQ---W---EQSISACP 533
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 50.1 bits (118), Expect = 2e-05
Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 18/123 (14%)
Query: 482 YTAVFLGTVNGRLLK-------INLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLY 534
YT +F+GT +G LLK ++L E +Q+ + EP+ ++ L+
Sbjct: 436 YTVLFIGTGDGWLLKAVSLGPWVHLIEELQLFDQ--------EPMRSLVLSQ--SKKLLF 485
Query: 535 LMTSHQMARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQ-QHFWTSA 593
+ Q+ ++ VA C + +C DCV A D YC W +RC + S QH TS
Sbjct: 486 AGSRSQLVQLPVADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSD 545
Query: 594 SEG 596
+ G
Sbjct: 546 TSG 548
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 49.7 bits (117), Expect = 3e-05
Identities = 32/121 (26%), Positives = 52/121 (42%), Gaps = 3/121 (2%)
Query: 482 YTAVFLGTVNGRLLK-INLNESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTSHQ 540
Y +F+ T G L K I+L ++ ++ + + EPV ++ + ++Y ++
Sbjct: 436 YDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDF-EPVQTLLLSSKKGNRFVYAGSNSG 494
Query: 541 MARVKVAACNVHSTCGDCVGAADAYCGWCALETRCTLQQDCTNSSQQHFWTSASEGPSRC 600
+ + +A C H TC DCV A D YC W C T S + S S C
Sbjct: 495 VVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQ-TESPSRGLIQEMSGDASVC 553
Query: 601 P 601
P
Sbjct: 554 P 554
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 48.1 bits (113), Expect = 8e-05
Identities = 76/319 (23%), Positives = 115/319 (36%), Gaps = 57/319 (17%)
Query: 316 SLLARICLPHGAGGDAKKLTE---SYIQLGLQCAGGAGRGDLYSRLVSV-----FPARER 367
S +AR+C + GG + L + S+++ L C+ ++ L +V R
Sbjct: 261 SRVARVC-KNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGRPV 319
Query: 368 LFAVFERPQGSPAARAAPAALCAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQGTG 427
+ AVF P S +A+CAF V AA+ R P V + V
Sbjct: 320 VLAVFSTPSNSIPG----SAVCAFDLTQV-AAVFEGRFREQKSPESIWTPVPEDQVPRPR 374
Query: 428 PAC---------------ERKLNIQLQPEQLDCGAAHLQHPLSILQPLKATPVFRAPGLT 472
P C + LN +D L H IL+ L + R
Sbjct: 375 PGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRHQLTRVA--V 432
Query: 473 SVAVASVNNYTAVFLGTVNGRLLKINLNESMQVVSRRVVTVAY----------------G 516
V N T VFLG+ G +LK + + ++V G
Sbjct: 433 DVGAGPWGNQTVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGGG 492
Query: 517 EPVHHVMQFD-PADSGYLYLMTSHQMARVKVAACNVHSTC-GDCVGAADAYCGWC----- 569
E ++ + A SG L + RV VA C +S C +C+G+ D YCGW
Sbjct: 493 ETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGSC 552
Query: 570 ---ALETRCTLQQDCTNSS 585
+ TR +QD + +S
Sbjct: 553 IFLSPGTRAAFEQDVSGAS 571
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 45.4 bits (106), Expect = 5e-04
Identities = 68/319 (21%), Positives = 126/319 (39%), Gaps = 36/319 (11%)
Query: 279 FVSAFLHPSDPPPGAQSYAYLALNSEARAGDKESQARSLLARICLPHGAGGDAKKLTE-- 336
FV A + P P + Q S++ARIC P+ GG + +
Sbjct: 223 FVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARIC-PNDTGGLRSLVNKWT 281
Query: 337 SYIQLGLQCA--GGAGRGDLYSRLVSVF------PARERLFAVFERPQGSPAARAAPAAL 388
++++ L C+ G + L VF P ++ +F + ++ +A+
Sbjct: 282 TFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFT----TSSSVFKGSAV 337
Query: 389 CAFRFADVRAAIRAARTACFVEPAPDVVAVLDSVVQ---GTGPACERKLNIQLQPEQLDC 445
C + +D++ A P +++ + GT P N++ E D
Sbjct: 338 CVYHLSDIQTVFNGP-FAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDD 396
Query: 446 GAAHLQ-HPL--SILQPLKATPVFRAPGL----TSVAVASVN----NYTAVFLGTVNGRL 494
++ HPL + + P+ P+ G T +AV VN Y +FLGT G +
Sbjct: 397 VVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTV 456
Query: 495 LKINLNESMQVVSRRVVTVAYGEPVHHV----MQFDPADSGYLYLMTSHQMARVKVAACN 550
K+ + + VS ++ +H M+ + LY+ ++ +++V + C+
Sbjct: 457 QKVVVLPTNNSVSGELILEELEVFKNHAPITTMKIS-SKKQQLYVSSNEGVSQVSLHRCH 515
Query: 551 VHST-CGDCVGAADAYCGW 568
++ T C DC A D YC W
Sbjct: 516 IYGTACADCCLARDPYCAW 534
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 45.1 bits (105), Expect = 7e-04
Identities = 36/132 (27%), Positives = 62/132 (46%), Gaps = 15/132 (11%)
Query: 452 HPL--SILQPLKATPVF-RAPG---LTSVAVASVN----NYTAVFLGTVNGRLLKINLNE 501
HPL ++P P+ + G L +AV V Y +F+GT NG +LK+
Sbjct: 408 HPLMYQAIKPAHKKPILVKTDGKYNLKQIAVDRVEAEDGQYDVLFIGTDNGIVLKVITIY 467
Query: 502 SMQVVSRRVVTVA----YGEPVHHVMQFDPADSGYLYLMTSHQMARVKVAACNVH-STCG 556
+ ++ S V + + +PV + + LY+ ++ +A+V+ C+++ S C
Sbjct: 468 NQEMESMEEVILEELQIFKDPVPIISMEISSKRQQLYIGSASAVAQVRFHHCDMYGSACA 527
Query: 557 DCVGAADAYCGW 568
DC A D YC W
Sbjct: 528 DCCLARDPYCAW 539
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 45.1 bits (105), Expect = 7e-04
Identities = 46/162 (28%), Positives = 70/162 (43%), Gaps = 12/162 (7%)
Query: 480 NNYTAVFLGTVNGRLLKINLN-ESMQVVSRRVVTVAYGEPVHHVMQFDPADSGYLYLMTS 538
+++ ++LGT G L K ++ +S + + EPV + +Q P G +++ S
Sbjct: 429 HSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRN-LQLAPTQ-GAVFVGFS 486
Query: 539 HQMARVKVAACNVHSTCGDCVGAADAYCGW-CALETRCTLQQDCTNSSQQHF------WT 591
+ RV A C+V+ +C DCV A D +C W T C L NS +Q W
Sbjct: 487 GGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWA 546
Query: 592 SASEGPSRCPAMTVLPSEIDVRQEYPGMILQISGSLPSLSGM 633
AS SR P I P IL++ P LS +
Sbjct: 547 CASGPMSRSLRPQSRPQIIKEVLAVPNSILEL--PCPHLSAL 586
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,951,887
Number of Sequences: 37866
Number of extensions: 3886946
Number of successful extensions: 12501
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 11960
Number of HSP's gapped (non-prelim): 255
length of query: 1925
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1808
effective length of database: 13,817,196
effective search space: 24981490368
effective search space used: 24981490368
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.