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Search of human proteins with 157694511
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157694511 nucleolar complex associated 2 homolog [Homo
sapiens]
(749 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157694511 nucleolar complex associated 2 homolog [Homo sapiens] 1488 0.0
gi|11545835 TSPY-like 2 [Homo sapiens] 47 6e-05
gi|115529449 upstream binding transcription factor, RNA polymera... 46 1e-04
gi|115529451 upstream binding transcription factor, RNA polymera... 46 1e-04
gi|7657671 upstream binding transcription factor, RNA polymerase... 46 1e-04
gi|83716024 kinesin family member 21B [Homo sapiens] 45 3e-04
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 45 3e-04
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 44 7e-04
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 44 7e-04
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 43 0.001
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 43 0.001
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 43 0.001
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 42 0.002
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 42 0.002
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 42 0.003
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 42 0.003
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 42 0.003
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 42 0.003
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 42 0.003
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 42 0.003
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 42 0.003
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 41 0.004
gi|215422388 death-domain associated protein isoform a [Homo sap... 41 0.004
gi|215422366 death-domain associated protein isoform b [Homo sap... 41 0.004
gi|55956788 nucleolin [Homo sapiens] 41 0.005
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 41 0.005
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 41 0.005
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 41 0.005
gi|226246554 hypothetical protein LOC643677 [Homo sapiens] 40 0.006
gi|27597090 suppressor of Ty 6 homolog [Homo sapiens] 40 0.008
>gi|157694511 nucleolar complex associated 2 homolog [Homo sapiens]
Length = 749
Score = 1488 bits (3853), Expect = 0.0
Identities = 749/749 (100%), Positives = 749/749 (100%)
Query: 1 MAAAGSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSAS 60
MAAAGSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSAS
Sbjct: 1 MAAAGSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSAS 60
Query: 61 RRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEA 120
RRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEA
Sbjct: 61 RRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEA 120
Query: 121 SEEEDGAEEGEDGDRVPRGLKGKKNSVPVTVAMVERWKQAAKQRLTPKLFHEVVQAFRAA 180
SEEEDGAEEGEDGDRVPRGLKGKKNSVPVTVAMVERWKQAAKQRLTPKLFHEVVQAFRAA
Sbjct: 121 SEEEDGAEEGEDGDRVPRGLKGKKNSVPVTVAMVERWKQAAKQRLTPKLFHEVVQAFRAA 180
Query: 181 VATTRGDQESAEANKFQVTDSAAFNALVTFCIRDLIGCLQKLLFGKVAKDSSRMLQPSSS 240
VATTRGDQESAEANKFQVTDSAAFNALVTFCIRDLIGCLQKLLFGKVAKDSSRMLQPSSS
Sbjct: 181 VATTRGDQESAEANKFQVTDSAAFNALVTFCIRDLIGCLQKLLFGKVAKDSSRMLQPSSS 240
Query: 241 PLWGKLRVDIKAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVV 300
PLWGKLRVDIKAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVV
Sbjct: 241 PLWGKLRVDIKAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVV 300
Query: 301 VWSTGEESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPGALPFISFMQW 360
VWSTGEESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPGALPFISFMQW
Sbjct: 301 VWSTGEESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPGALPFISFMQW 360
Query: 361 TLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKKETYQSVYNWQYVHCLFLWCRVLS 420
TLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKKETYQSVYNWQYVHCLFLWCRVLS
Sbjct: 361 TLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKKETYQSVYNWQYVHCLFLWCRVLS 420
Query: 421 TAGPSEALQPLVYPLAQVIIGCIKLIPTARFYPLRMHCIRALTLLSGSSGAFIPVLPFIL 480
TAGPSEALQPLVYPLAQVIIGCIKLIPTARFYPLRMHCIRALTLLSGSSGAFIPVLPFIL
Sbjct: 421 TAGPSEALQPLVYPLAQVIIGCIKLIPTARFYPLRMHCIRALTLLSGSSGAFIPVLPFIL 480
Query: 481 EMFQQVDFNRKPGRMSSKPINFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHC 540
EMFQQVDFNRKPGRMSSKPINFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHC
Sbjct: 481 EMFQQVDFNRKPGRMSSKPINFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHC 540
Query: 541 IGFPELVLPVVLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQA 600
IGFPELVLPVVLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQA
Sbjct: 541 IGFPELVLPVVLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQA 600
Query: 601 VEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDED 660
VEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDED
Sbjct: 601 VEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDED 660
Query: 661 RKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDA 720
RKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDA
Sbjct: 661 RKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDA 720
Query: 721 EAGLAPGELQQLAQGPEDELEDLQLSEDD 749
EAGLAPGELQQLAQGPEDELEDLQLSEDD
Sbjct: 721 EAGLAPGELQQLAQGPEDELEDLQLSEDD 749
>gi|11545835 TSPY-like 2 [Homo sapiens]
Length = 693
Score = 47.0 bits (110), Expect = 6e-05
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 20/129 (15%)
Query: 19 FLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKD 78
F S +++ S+S+N EA EA+ D G +E ++ S D
Sbjct: 548 FWGSHGNNQDSSDSDN-------EADEASDDEDNDGNEGDNEGSDDDGNEGDNEGSDDDD 600
Query: 79 RDPEFY-KFLQENDQSLLNFSD-----SDSSEEEEGPFHSLP---DVLEEASEEEDGA-- 127
RD E+Y K +++ D+ ++ D SD S EEEG + D+ EE + EE+G+
Sbjct: 601 RDIEYYEKVIEDFDKDQADYEDVIEIISDESVEEEGIEEGIQQDEDIYEEGNYEEEGSED 660
Query: 128 --EEGEDGD 134
EEGED D
Sbjct: 661 VWEEGEDSD 669
Score = 34.7 bits (78), Expect = 0.33
Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 11/64 (17%)
Query: 652 KMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSS 711
K+ + D+D+ ++D+ ++ S E + EG E G++ DE+ EEG +
Sbjct: 608 KVIEDFDKDQADYEDVIEIISDESVEEEGIEE-----------GIQQDEDIYEEGNYEEE 656
Query: 712 NSED 715
SED
Sbjct: 657 GSED 660
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 15/155 (9%)
Query: 577 VQENSAYICSRRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKL---RDREIQLE 633
++E I SR QR+S Q E ++KL E+ ++ W K +DR E
Sbjct: 556 LKERMVEIGSRWQRIS-----QSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKE 610
Query: 634 -ISGKER-LEDLNFPEIKRRKMA----DRKDEDRKQFKDLFDLNSSEEDDTEG-FSERGI 686
IS K + + L P K + +ED ++ +D D + EEDD G SE G
Sbjct: 611 YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG 670
Query: 687 LRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAE 721
S+ +D ++ EE +ED + ED D D +
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDED 705
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 15/155 (9%)
Query: 577 VQENSAYICSRRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKL---RDREIQLE 633
++E I SR QR+S Q E ++KL E+ ++ W K +DR E
Sbjct: 556 LKERMVEIGSRWQRIS-----QSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKE 610
Query: 634 -ISGKER-LEDLNFPEIKRRKMA----DRKDEDRKQFKDLFDLNSSEEDDTEG-FSERGI 686
IS K + + L P K + +ED ++ +D D + EEDD G SE G
Sbjct: 611 YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG 670
Query: 687 LRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAE 721
S+ +D ++ EE +ED + ED D D +
Sbjct: 671 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDED 705
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/155 (29%), Positives = 69/155 (44%), Gaps = 15/155 (9%)
Query: 577 VQENSAYICSRRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKL---RDREIQLE 633
++E I SR QR+S Q E ++KL E+ ++ W K +DR E
Sbjct: 593 LKERMVEIGSRWQRIS-----QSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKE 647
Query: 634 -ISGKER-LEDLNFPEIKRRKMA----DRKDEDRKQFKDLFDLNSSEEDDTEG-FSERGI 686
IS K + + L P K + +ED ++ +D D + EEDD G SE G
Sbjct: 648 YISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGG 707
Query: 687 LRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAE 721
S+ +D ++ EE +ED + ED D D +
Sbjct: 708 DSSESSSEDESEDGDENEEDDEDEDDDEDDDEDED 742
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 44.7 bits (104), Expect = 3e-04
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 16/189 (8%)
Query: 563 VANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQ-AVEAWEKLTREEGTPLTLYYSH 621
+ NY R++++L K+ E+ A S R+ +S + ++ A G+P +
Sbjct: 478 IQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDA 537
Query: 622 WRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGF 681
+R K+ LE L E+++R+ + K+ +K+ K L NS E D+ E
Sbjct: 538 SEVIR--------RAKQDLERLKKKEVRQRRKSPEKEAFKKRAK-LQQENSEETDENEAE 588
Query: 682 SERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDA-----EAGLAPGELQ-QLAQG 735
E ++EDE+ G E+S D DP+ +A LA + ++ Q
Sbjct: 589 EEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQK 648
Query: 736 PEDELEDLQ 744
DELE+ Q
Sbjct: 649 LIDELENSQ 657
Score = 32.3 bits (72), Expect = 1.7
Identities = 39/143 (27%), Positives = 61/143 (42%), Gaps = 23/143 (16%)
Query: 16 VDEFLASGFDSESESES--ENSPQAETREAREAARSPDKP--GGSPSASRRKGRASE--- 68
++E +SE+ +ES + +A R SP P GGSP++S ASE
Sbjct: 485 IEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMED--ASEVIR 542
Query: 69 -HKDQLSRLKDRD-------PEFYKF-----LQENDQSLLNFSDSDSSEEEEGPFHSLPD 115
K L RLK ++ PE F LQ+ + + ++++ EEE +
Sbjct: 543 RAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEE 602
Query: 116 VLEEASEEEDGAEEG-EDGDRVP 137
E +E+ G+EE D D P
Sbjct: 603 EGREDEDEDSGSEESLVDSDSDP 625
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 44.7 bits (104), Expect = 3e-04
Identities = 22/102 (21%), Positives = 56/102 (54%), Gaps = 4/102 (3%)
Query: 650 RRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEED 709
+++M ++++E+ K+ +++ EE++ E ++ + ++ E + +DEE+ +ED
Sbjct: 370 QQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDED 429
Query: 710 SSNSEDGDPDAEAGLAP--GELQQ--LAQGPEDELEDLQLSE 747
+G+P + G GE+++ L + +D+L++L E
Sbjct: 430 GGQKPEGEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEME 471
Score = 32.3 bits (72), Expect = 1.7
Identities = 38/178 (21%), Positives = 64/178 (35%), Gaps = 13/178 (7%)
Query: 19 FLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKD 78
F S + ESE E S + R S D+ R++ RA + + +K+
Sbjct: 329 FAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQ--------RKRMRAFQQE-----MKE 375
Query: 79 RDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPR 138
++ E K +E + + + +++ + + EE E +D +E EDG + P
Sbjct: 376 KEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPE 435
Query: 139 GLKGKKNSVPVTVAMVERWKQAAKQRLTPKLFHEVVQAFRAAVATTRGDQESAEANKF 196
G + T VE Q E+ F A + T G A F
Sbjct: 436 GEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENF 493
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 43.5 bits (101), Expect = 7e-04
Identities = 46/173 (26%), Positives = 74/173 (42%), Gaps = 32/173 (18%)
Query: 585 CSRRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQ--------LEISG 636
CS +Q G + EK EEG+ L+ + D+E++ E G
Sbjct: 552 CSEKQSED-GSEREFEENGLEKDLDEEGSEKELH----ENVLDKELEENDSENSEFEDDG 606
Query: 637 KERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGV 696
E++ D E + + +D K+E+ ++ +FD S E++D E E+G+
Sbjct: 607 SEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGL---------- 656
Query: 697 EDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
E ++ EEG+ D E+ D D E + A G E E D +L EDD
Sbjct: 657 EAADKKAEEGDADEKLFEESD-DKE--------DEDADGKEVEDADEKLFEDD 700
Score = 36.6 bits (83), Expect = 0.088
Identities = 37/139 (26%), Positives = 55/139 (39%), Gaps = 10/139 (7%)
Query: 6 SRKRRLAELTVDEFLA--SGFDSESESESENSPQAET------REAREAARSPDKPGGSP 57
S+K+ L + LA S D ESE E P E+ +E+ E GS
Sbjct: 503 SKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSE 562
Query: 58 SASRRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSE--EEEGPFHSLPD 115
G + ++ S + + K L+END F D S + +EEG +
Sbjct: 563 REFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDE 622
Query: 116 VLEEASEEEDGAEEGEDGD 134
+E EEED E+ D +
Sbjct: 623 DSDEKEEEEDTYEKVFDDE 641
Score = 35.8 bits (81), Expect = 0.15
Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
Query: 27 ESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASE-HKDQLSR-LKDRDPEFY 84
E +SE E+ +++ + + + G +G E H++ L + L++ D E
Sbjct: 541 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS 600
Query: 85 KFLQENDQSLLNFS--------DSDSSEEEEGPFHSLPDVLEEASEEEDGAEE 129
+F + + +L+ DSD EEEE + + D + E+E+ A+E
Sbjct: 601 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADE 653
Score = 35.8 bits (81), Expect = 0.15
Identities = 36/148 (24%), Positives = 62/148 (41%), Gaps = 8/148 (5%)
Query: 605 EKLTREEGTPLTLYYSHWRKLRDREIQLEISGKE--RLEDLNFPEIKRRKMADRKDEDRK 662
EK+ EEG+ K + + ++ E ED + + K + AD+K E+
Sbjct: 608 EKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGD 667
Query: 663 QFKDLFDLNSSEED-DTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAE 721
+ LF+ + +ED D +G L EDD+ +E+ +E+ +SE D++
Sbjct: 668 ADEKLFEESDDKEDEDADGKEVEDADEKL-----FEDDDSNEKLFDEEEDSSEKLFDDSD 722
Query: 722 AGLAPGELQQLAQGPEDELEDLQLSEDD 749
G + +GP LS DD
Sbjct: 723 ERGTLGGFGSVEEGPLSTGSSFILSSDD 750
Score = 33.1 bits (74), Expect = 0.97
Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 7/112 (6%)
Query: 637 KERLEDLNFP---EIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTR 693
KE +DLN E+ K ++ D +++ +D + S + + E F E G+ + L
Sbjct: 519 KESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSERE-FEENGLEKDLDEE 577
Query: 694 HGVEDDEE---DEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELED 742
++ E D+E E DS NSE D +E L ++ DE E+
Sbjct: 578 GSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEE 629
Score = 32.0 bits (71), Expect = 2.2
Identities = 39/158 (24%), Positives = 66/158 (41%), Gaps = 21/158 (13%)
Query: 597 EQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADR 656
E++A E + EEG P + + ++ E + G E ED E K++ + +
Sbjct: 455 EKEAEEGCPEKESEEGCPKRGFEGSCSQ-KESEEGNPVRGSE--EDSPKKESKKKTLKND 511
Query: 657 KDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDG 716
+E+ + DLN E++ T+ EDD E E + + SEDG
Sbjct: 512 CEENGLAKESEDDLNKESEEEVG-----------PTKESEEDDSEKESDEDCSEKQSEDG 560
Query: 717 -DPDAEAGLAPGELQQLAQGPEDELE----DLQLSEDD 749
+ + E +L + +G E EL D +L E+D
Sbjct: 561 SEREFEENGLEKDLDE--EGSEKELHENVLDKELEEND 596
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 43.5 bits (101), Expect = 7e-04
Identities = 46/173 (26%), Positives = 74/173 (42%), Gaps = 32/173 (18%)
Query: 585 CSRRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQ--------LEISG 636
CS +Q G + EK EEG+ L+ + D+E++ E G
Sbjct: 552 CSEKQSED-GSEREFEENGLEKDLDEEGSEKELH----ENVLDKELEENDSENSEFEDDG 606
Query: 637 KERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGV 696
E++ D E + + +D K+E+ ++ +FD S E++D E E+G+
Sbjct: 607 SEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGL---------- 656
Query: 697 EDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
E ++ EEG+ D E+ D D E + A G E E D +L EDD
Sbjct: 657 EAADKKAEEGDADEKLFEESD-DKE--------DEDADGKEVEDADEKLFEDD 700
Score = 36.6 bits (83), Expect = 0.088
Identities = 37/139 (26%), Positives = 55/139 (39%), Gaps = 10/139 (7%)
Query: 6 SRKRRLAELTVDEFLA--SGFDSESESESENSPQAET------REAREAARSPDKPGGSP 57
S+K+ L + LA S D ESE E P E+ +E+ E GS
Sbjct: 503 SKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSE 562
Query: 58 SASRRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSE--EEEGPFHSLPD 115
G + ++ S + + K L+END F D S + +EEG +
Sbjct: 563 REFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDE 622
Query: 116 VLEEASEEEDGAEEGEDGD 134
+E EEED E+ D +
Sbjct: 623 DSDEKEEEEDTYEKVFDDE 641
Score = 35.8 bits (81), Expect = 0.15
Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 10/113 (8%)
Query: 27 ESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASE-HKDQLSR-LKDRDPEFY 84
E +SE E+ +++ + + + G +G E H++ L + L++ D E
Sbjct: 541 EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENS 600
Query: 85 KFLQENDQSLLNFS--------DSDSSEEEEGPFHSLPDVLEEASEEEDGAEE 129
+F + + +L+ DSD EEEE + + D + E+E+ A+E
Sbjct: 601 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADE 653
Score = 35.8 bits (81), Expect = 0.15
Identities = 36/148 (24%), Positives = 62/148 (41%), Gaps = 8/148 (5%)
Query: 605 EKLTREEGTPLTLYYSHWRKLRDREIQLEISGKE--RLEDLNFPEIKRRKMADRKDEDRK 662
EK+ EEG+ K + + ++ E ED + + K + AD+K E+
Sbjct: 608 EKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGD 667
Query: 663 QFKDLFDLNSSEED-DTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAE 721
+ LF+ + +ED D +G L EDD+ +E+ +E+ +SE D++
Sbjct: 668 ADEKLFEESDDKEDEDADGKEVEDADEKL-----FEDDDSNEKLFDEEEDSSEKLFDDSD 722
Query: 722 AGLAPGELQQLAQGPEDELEDLQLSEDD 749
G + +GP LS DD
Sbjct: 723 ERGTLGGFGSVEEGPLSTGSSFILSSDD 750
Score = 33.1 bits (74), Expect = 0.97
Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 7/112 (6%)
Query: 637 KERLEDLNFP---EIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTR 693
KE +DLN E+ K ++ D +++ +D + S + + E F E G+ + L
Sbjct: 519 KESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSERE-FEENGLEKDLDEE 577
Query: 694 HGVEDDEE---DEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELED 742
++ E D+E E DS NSE D +E L ++ DE E+
Sbjct: 578 GSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEE 629
Score = 32.0 bits (71), Expect = 2.2
Identities = 39/158 (24%), Positives = 66/158 (41%), Gaps = 21/158 (13%)
Query: 597 EQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADR 656
E++A E + EEG P + + ++ E + G E ED E K++ + +
Sbjct: 455 EKEAEEGCPEKESEEGCPKRGFEGSCSQ-KESEEGNPVRGSE--EDSPKKESKKKTLKND 511
Query: 657 KDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDG 716
+E+ + DLN E++ T+ EDD E E + + SEDG
Sbjct: 512 CEENGLAKESEDDLNKESEEEVG-----------PTKESEEDDSEKESDEDCSEKQSEDG 560
Query: 717 -DPDAEAGLAPGELQQLAQGPEDELE----DLQLSEDD 749
+ + E +L + +G E EL D +L E+D
Sbjct: 561 SEREFEENGLEKDLDE--EGSEKELHENVLDKELEEND 596
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 12/89 (13%)
Query: 634 ISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTR 693
+ +E ED + + + D +DED ++ + D++ EE+D EG+++
Sbjct: 167 LDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYND---------- 216
Query: 694 HGVEDDEEDEEE-GEEDSSNSEDGDPDAE 721
G DDEEDEEE GEE+ +P+ E
Sbjct: 217 -GEVDDEEDEEELGEEERGQKRKREPEDE 244
Score = 34.7 bits (78), Expect = 0.33
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 655 DRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSE 714
+ +DED +++ + + EED+ E E G V +EE++EEG D +
Sbjct: 170 EEEDEDEEEYDEDAQVVEDEEDEDE--EEEG------EEEDVSGEEEEDEEGYNDGEVDD 221
Query: 715 DGDPDAEAGLAPGELQQLAQGPEDELED 742
+ D + G Q+ + PEDE ED
Sbjct: 222 EEDEEELGEEERG--QKRKREPEDEGED 247
Score = 33.1 bits (74), Expect = 0.97
Identities = 32/134 (23%), Positives = 59/134 (44%), Gaps = 33/134 (24%)
Query: 638 ERLEDLNFPEIKRRKMADRKDEDRKQFK--------DLFDLNSSE--EDDTEGFSERGIL 687
++LE+L ++ ++ + D FK D +D + E + D EG+ E
Sbjct: 110 KKLENLKSLDLFNCEVTNLNDYRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVE---- 165
Query: 688 RPLSTRHGVEDDEEDEEEGEED-------SSNSEDGDPDAEAGLAPGELQQLAQG----- 735
G++D+EEDE+E E D ED + + E GE ++ +G
Sbjct: 166 -------GLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGE 218
Query: 736 PEDELEDLQLSEDD 749
+DE ++ +L E++
Sbjct: 219 VDDEEDEEELGEEE 232
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Query: 647 EIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEG 706
E+ RR A R + K+ + + S E + G S+ + GVE+D E++EE
Sbjct: 158 EVDRR--ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEV 215
Query: 707 EEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
EED+ E+ D D E E ++ + E+E E+ + +D+
Sbjct: 216 EEDAEEDEEVDEDGE----EEEEEEEEEEEEEEEEEEEYEQDE 254
Score = 36.2 bits (82), Expect = 0.11
Identities = 28/124 (22%), Positives = 46/124 (37%)
Query: 27 ESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFYKF 86
E + + S Q+ E D GS +S +G +E++++ + E +
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217
Query: 87 LQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRGLKGKKNS 146
E D+ + + + EEEE + E +E D EEG D D S
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
Query: 147 VPVT 150
V T
Sbjct: 278 VSFT 281
Score = 31.6 bits (70), Expect = 2.8
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 100 SDSSEEEEGPFHSLPDVLEEASEEEDGA--EEGEDGDRVPRGLKGKKNSVPVTVAMVERW 157
+DS EE++G + L D+L E E++D E E +G K K + + T ++
Sbjct: 3 ADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKP 62
Query: 158 KQAAKQRLTPKLFHEVVQAFRAAVATTRGDQESAEANK 195
++Q ++ L V R + +T+G + N+
Sbjct: 63 SVHSRQLVSKPLSSSVSNNKR--IVSTKGKSATEYKNE 98
Score = 30.4 bits (67), Expect = 6.3
Identities = 25/112 (22%), Positives = 43/112 (38%), Gaps = 4/112 (3%)
Query: 26 SESESESENSPQ---AETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPE 82
S S +N P+ R+ A+SP P GS R + Q S+ + E
Sbjct: 120 SASREPYKNQPEKTCVRKRDPERRAKSPT-PDGSERIGLEVDRRASRSSQSSKEEVNSEE 178
Query: 83 FYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGD 134
+ + + +++ EEEG + + E + E+ E EDG+
Sbjct: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
Query: 647 EIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEG 706
E+ RR A R + K+ + + S E + G S+ + GVE+D E++EE
Sbjct: 158 EVDRR--ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEV 215
Query: 707 EEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
EED+ E+ D D E E ++ + E+E E+ + +D+
Sbjct: 216 EEDAEEDEEVDEDGE----EEEEEEEEEEEEEEEEEEEYEQDE 254
Score = 36.2 bits (82), Expect = 0.11
Identities = 28/124 (22%), Positives = 46/124 (37%)
Query: 27 ESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFYKF 86
E + + S Q+ E D GS +S +G +E++++ + E +
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEE 217
Query: 87 LQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRGLKGKKNS 146
E D+ + + + EEEE + E +E D EEG D D S
Sbjct: 218 DAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
Query: 147 VPVT 150
V T
Sbjct: 278 VSFT 281
Score = 31.6 bits (70), Expect = 2.8
Identities = 24/98 (24%), Positives = 45/98 (45%), Gaps = 4/98 (4%)
Query: 100 SDSSEEEEGPFHSLPDVLEEASEEEDGA--EEGEDGDRVPRGLKGKKNSVPVTVAMVERW 157
+DS EE++G + L D+L E E++D E E +G K K + + T ++
Sbjct: 3 ADSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKP 62
Query: 158 KQAAKQRLTPKLFHEVVQAFRAAVATTRGDQESAEANK 195
++Q ++ L V R + +T+G + N+
Sbjct: 63 SVHSRQLVSKPLSSSVSNNKR--IVSTKGKSATEYKNE 98
Score = 30.4 bits (67), Expect = 6.3
Identities = 25/112 (22%), Positives = 43/112 (38%), Gaps = 4/112 (3%)
Query: 26 SESESESENSPQ---AETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPE 82
S S +N P+ R+ A+SP P GS R + Q S+ + E
Sbjct: 120 SASREPYKNQPEKTCVRKRDPERRAKSPT-PDGSERIGLEVDRRASRSSQSSKEEVNSEE 178
Query: 83 FYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGD 134
+ + + +++ EEEG + + E + E+ E EDG+
Sbjct: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGE 230
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/129 (28%), Positives = 58/129 (44%), Gaps = 16/129 (12%)
Query: 626 RDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDR----KQFKDLFDLNSSEEDDTEGF 681
R+ E + E GKE E + ++ +RK E+R ++ ++ D EE++TEG
Sbjct: 745 REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGR 804
Query: 682 SER----GILRPLSTRHGV----EDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLA 733
E G + G E++EE E E EE E+G+ + E G GE
Sbjct: 805 GEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGE----E 860
Query: 734 QGPEDELED 742
+G E E E+
Sbjct: 861 EGEEGEGEE 869
Score = 37.7 bits (86), Expect = 0.039
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 9/68 (13%)
Query: 674 EEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLA 733
EE + EG E G G ++EE EEEGEE+ E+G+ + E GE++
Sbjct: 975 EEGEGEGEEEEG--------EGEGEEEEGEEEGEEEGEGEEEGEGEGEEE-EEGEVEGEV 1025
Query: 734 QGPEDELE 741
+G E E E
Sbjct: 1026 EGEEGEGE 1033
Score = 36.2 bits (82), Expect = 0.11
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 12/123 (9%)
Query: 629 EIQLEISGKERLE--DLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGI 686
E + E G+E+ E ++ E++ K ++E+ + ++ + EE++ EG E G
Sbjct: 798 EEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEE--EEGEGEEEEGEGEEEEGE 855
Query: 687 LRPLSTRHGVEDDEE--------DEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPED 738
+ E +EE +EEEGE + +G+ + E G GE + +G E+
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915
Query: 739 ELE 741
E E
Sbjct: 916 EGE 918
Score = 35.8 bits (81), Expect = 0.15
Identities = 32/122 (26%), Positives = 50/122 (40%), Gaps = 8/122 (6%)
Query: 23 GFDSESESESENSPQA-ETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDP 81
G + E E E E + E R +E + G +GR E K++ ++ +
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE-KEEGGEVEGGEV 819
Query: 82 EFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRGLK 141
E K +E ++ + EEEEG EE E G EEGE+G+ G +
Sbjct: 820 EEGKGEREEEE------EEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEE 873
Query: 142 GK 143
G+
Sbjct: 874 GE 875
Score = 35.4 bits (80), Expect = 0.20
Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 8/134 (5%)
Query: 5 GSRKRR---LAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSASR 61
G RK + L++ D+ S ++S E+E+ P+ E S + R
Sbjct: 617 GGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHW--QDEER 674
Query: 62 RKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEAS 121
KG + + ++ R + + E ++ + + + + E E+G +EE
Sbjct: 675 EKGEKDKGRGEMERPGEGEKEL---AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGG 731
Query: 122 EEEDGAEEGEDGDR 135
EEE G E E+GDR
Sbjct: 732 EEEHGEGEEEEGDR 745
Score = 34.7 bits (78), Expect = 0.33
Identities = 37/164 (22%), Positives = 69/164 (42%), Gaps = 14/164 (8%)
Query: 589 QRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEI 648
+R G E E W+K EE H + +R ++E G+E + E
Sbjct: 687 ERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQK---ERNQEMEEGGEEEHGEGEEEEG 743
Query: 649 KRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVED---DEEDEEE 705
R + +++ E +++ EE + E E G R R G E+ +E D+ E
Sbjct: 744 DREEEEEKEGEGKEE-------GEGEEVEGEREKEEGE-RKKEERAGKEEKGEEEGDQGE 795
Query: 706 GEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
GEE+ + + + + GE+++ E+E E+ + E++
Sbjct: 796 GEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEE 839
Score = 34.3 bits (77), Expect = 0.43
Identities = 30/131 (22%), Positives = 51/131 (38%), Gaps = 9/131 (6%)
Query: 17 DEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRL 76
+E G D E E E E + E E + G +G E + +
Sbjct: 935 EEGEGEGEDGEGEGEEE---EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGE 991
Query: 77 KDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASE--EEDGAEEGEDGD 134
++ E + E ++ + + EEEEG + E E EE+G EEGE+ +
Sbjct: 992 EEEGEEEGEEEGEGEEE----GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEERE 1047
Query: 135 RVPRGLKGKKN 145
+ G + ++N
Sbjct: 1048 KEGEGEENRRN 1058
Score = 33.1 bits (74), Expect = 0.97
Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 2/69 (2%)
Query: 674 EEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQ-L 732
EE++ EG E G E +EE E EGEE+ +G+ + E G GE ++
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEG-EGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGE 1040
Query: 733 AQGPEDELE 741
+G E E E
Sbjct: 1041 EEGEEREKE 1049
Score = 32.3 bits (72), Expect = 1.7
Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 11/69 (15%)
Query: 674 EEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLA 733
EE + EG E G E++ E EEEGE + E+G+ + E GE
Sbjct: 984 EEGEGEGEEEEG-------EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE----G 1032
Query: 734 QGPEDELED 742
+G E+E E+
Sbjct: 1033 EGEEEEGEE 1041
Score = 32.0 bits (71), Expect = 2.2
Identities = 30/131 (22%), Positives = 47/131 (35%), Gaps = 10/131 (7%)
Query: 5 GSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKG 64
G R+ E +E G + E E E E E E + G +G
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG 883
Query: 65 RASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEE-EGPFHSLPDVLEEASEE 123
++ ++ + E E ++ + + EEE EG + E EE
Sbjct: 884 EGEGEEEGEGEGEEEEGE-----GEGEEE----GEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Query: 124 EDGAEEGEDGD 134
E+G EGEDG+
Sbjct: 935 EEGEGEGEDGE 945
Score = 30.4 bits (67), Expect = 6.3
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 5/76 (6%)
Query: 674 EEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQ-QL 732
EE + EG E G G ++EE E EGEE+ +G+ + E G GE + +
Sbjct: 872 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG----EGEGEEEEGEGKGEEEGEE 927
Query: 733 AQGPEDELEDLQLSED 748
+G +E E ED
Sbjct: 928 GEGEGEEEEGEGEGED 943
Score = 30.4 bits (67), Expect = 6.3
Identities = 26/107 (24%), Positives = 41/107 (38%)
Query: 633 EISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLST 692
E G+E E E K + +E + ++ E+ + EG E G
Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960
Query: 693 RHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDE 739
E +EE E EGEE E+ + + E GE + +G +E
Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 16/129 (12%)
Query: 624 KLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSE 683
KL + E LE KE +R+ D ++ED F+D+ S+ED+ F
Sbjct: 206 KLSEMEAYLENIEKEE---------ERKDDNDEEEEDIDFFEDI----DSDEDEGGLFGS 252
Query: 684 RGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDA---EAGLAPGELQQLAQGPEDEL 740
+ + S+R+ D D E +ED +N D + D+ + +A E ++L+ DE
Sbjct: 253 KKLKSGKSSRNLKYKDFFDPVESDEDITNVHDDELDSNKEDDEIAEEEAEELSISETDED 312
Query: 741 EDLQLSEDD 749
+DLQ +ED+
Sbjct: 313 DDLQENEDN 321
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/100 (23%), Positives = 47/100 (47%)
Query: 650 RRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEED 709
R+ + + K E+R DL D++ SE + S S E++EE+EE +
Sbjct: 237 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 296
Query: 710 SSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
S E+ + + E ++ ++ +E+ + ++SED+
Sbjct: 297 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 336
Score = 33.1 bits (74), Expect = 0.97
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 11/127 (8%)
Query: 622 WRKLRDREIQLEISGKER--LEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTE 679
W + + RE+ E S +ER LE L + RKM +++ E R+Q E E
Sbjct: 136 WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ-------KERERRAEE 188
Query: 680 GFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGE--LQQLAQGPE 737
ER R +S H ++ ++ S S P L G +++
Sbjct: 189 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER 248
Query: 738 DELEDLQ 744
D L DLQ
Sbjct: 249 DLLSDLQ 255
Score = 33.1 bits (74), Expect = 0.97
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 63 KGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASE 122
K E +D LS L+D K S + S S+ EEEE EE+ E
Sbjct: 241 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 300
Query: 123 EEDGAEEGED 132
EE+ EE E+
Sbjct: 301 EEEEEEEEEE 310
Score = 30.4 bits (67), Expect = 6.3
Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 25 DSESESESENSPQAET---REAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDP 81
DSE ++ S S AE+ E E ++ GS S + E +++ + +
Sbjct: 259 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE- 317
Query: 82 EFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRG 139
+ ++QS S+ + SE+EE + V+ E+ + D E E + V G
Sbjct: 318 ------EASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 369
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/100 (23%), Positives = 47/100 (47%)
Query: 650 RRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEED 709
R+ + + K E+R DL D++ SE + S S E++EE+EE +
Sbjct: 247 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 306
Query: 710 SSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
S E+ + + E ++ ++ +E+ + ++SED+
Sbjct: 307 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 346
Score = 33.1 bits (74), Expect = 0.97
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 11/127 (8%)
Query: 622 WRKLRDREIQLEISGKER--LEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTE 679
W + + RE+ E S +ER LE L + RKM +++ E R+Q E E
Sbjct: 146 WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ-------KERERRAEE 198
Query: 680 GFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGE--LQQLAQGPE 737
ER R +S H ++ ++ S S P L G +++
Sbjct: 199 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER 258
Query: 738 DELEDLQ 744
D L DLQ
Sbjct: 259 DLLSDLQ 265
Score = 33.1 bits (74), Expect = 0.97
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 63 KGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASE 122
K E +D LS L+D K S + S S+ EEEE EE+ E
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310
Query: 123 EEDGAEEGED 132
EE+ EE E+
Sbjct: 311 EEEEEEEEEE 320
Score = 30.4 bits (67), Expect = 6.3
Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 25 DSESESESENSPQAET---REAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDP 81
DSE ++ S S AE+ E E ++ GS S + E +++ + +
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE- 327
Query: 82 EFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRG 139
+ ++QS S+ + SE+EE + V+ E+ + D E E + V G
Sbjct: 328 ------EASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 379
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/100 (23%), Positives = 47/100 (47%)
Query: 650 RRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEED 709
R+ + + K E+R DL D++ SE + S S E++EE+EE +
Sbjct: 238 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 297
Query: 710 SSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
S E+ + + E ++ ++ +E+ + ++SED+
Sbjct: 298 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 337
Score = 34.7 bits (78), Expect = 0.33
Identities = 40/162 (24%), Positives = 62/162 (38%), Gaps = 14/162 (8%)
Query: 587 RRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKER--LEDLN 644
R+++ V E++ K REE W + + RE+ E S +ER LE L
Sbjct: 105 RKEKKHARVKEKEREHERRKRHREEQDKAR---REWERQKRREMAREHSRRERDRLEQLE 161
Query: 645 FPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEE 704
+ RKM +++ E R+Q E E ER R +S H ++ ++
Sbjct: 162 RKRERERKMREQQKEQREQ-------KERERRAEERRKEREARREVSAHHRTMREDYSDK 214
Query: 705 EGEEDSSNSEDGDPDAEAGLAPGE--LQQLAQGPEDELEDLQ 744
S S P L G +++ D L DLQ
Sbjct: 215 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 256
Score = 33.1 bits (74), Expect = 0.97
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 63 KGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASE 122
K E +D LS L+D K S + S S+ EEEE EE+ E
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 301
Query: 123 EEDGAEEGED 132
EE+ EE E+
Sbjct: 302 EEEEEEEEEE 311
Score = 30.4 bits (67), Expect = 6.3
Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 25 DSESESESENSPQAET---REAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDP 81
DSE ++ S S AE+ E E ++ GS S + E +++ + +
Sbjct: 260 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE- 318
Query: 82 EFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRG 139
+ ++QS S+ + SE+EE + V+ E+ + D E E + V G
Sbjct: 319 ------EASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 370
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/100 (23%), Positives = 47/100 (47%)
Query: 650 RRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEED 709
R+ + + K E+R DL D++ SE + S S E++EE+EE +
Sbjct: 247 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 306
Query: 710 SSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
S E+ + + E ++ ++ +E+ + ++SED+
Sbjct: 307 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 346
Score = 33.1 bits (74), Expect = 0.97
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 63 KGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASE 122
K E +D LS L+D K S + S S+ EEEE EE+ E
Sbjct: 251 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 310
Query: 123 EEDGAEEGED 132
EE+ EE E+
Sbjct: 311 EEEEEEEEEE 320
Score = 31.2 bits (69), Expect = 3.7
Identities = 40/171 (23%), Positives = 62/171 (36%), Gaps = 23/171 (13%)
Query: 587 RRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKER------- 639
R+++ V E++ K REE W + + RE+ E S +ER
Sbjct: 105 RKEKKHARVKEKEREHERRKRHREEQDKAR---REWERQKRREMAREHSRRERGNDGVCL 161
Query: 640 ----LEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHG 695
LE L + RKM +++ E R+Q E E ER R +S H
Sbjct: 162 FRDRLEQLERKRERERKMREQQKEQREQ-------KERERRAEERRKEREARREVSAHHR 214
Query: 696 VEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGE--LQQLAQGPEDELEDLQ 744
++ ++ S S P L G +++ D L DLQ
Sbjct: 215 TMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 265
Score = 30.4 bits (67), Expect = 6.3
Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 25 DSESESESENSPQAET---REAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDP 81
DSE ++ S S AE+ E E ++ GS S + E +++ + +
Sbjct: 269 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE- 327
Query: 82 EFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRG 139
+ ++QS S+ + SE+EE + V+ E+ + D E E + V G
Sbjct: 328 ------EASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 379
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/100 (23%), Positives = 47/100 (47%)
Query: 650 RRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEED 709
R+ + + K E+R DL D++ SE + S S E++EE+EE +
Sbjct: 215 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 274
Query: 710 SSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
S E+ + + E ++ ++ +E+ + ++SED+
Sbjct: 275 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 314
Score = 33.1 bits (74), Expect = 0.97
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 11/127 (8%)
Query: 622 WRKLRDREIQLEISGKER--LEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTE 679
W + + RE+ E S +ER LE L + RKM +++ E R+Q E E
Sbjct: 114 WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ-------KERERRAEE 166
Query: 680 GFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGE--LQQLAQGPE 737
ER R +S H ++ ++ S S P L G +++
Sbjct: 167 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER 226
Query: 738 DELEDLQ 744
D L DLQ
Sbjct: 227 DLLSDLQ 233
Score = 33.1 bits (74), Expect = 0.97
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 63 KGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASE 122
K E +D LS L+D K S + S S+ EEEE EE+ E
Sbjct: 219 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 278
Query: 123 EEDGAEEGED 132
EE+ EE E+
Sbjct: 279 EEEEEEEEEE 288
Score = 30.4 bits (67), Expect = 6.3
Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 25 DSESESESENSPQAET---REAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDP 81
DSE ++ S S AE+ E E ++ GS S + E +++ + +
Sbjct: 237 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE- 295
Query: 82 EFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRG 139
+ ++QS S+ + SE+EE + V+ E+ + D E E + V G
Sbjct: 296 ------EASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 347
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/100 (23%), Positives = 47/100 (47%)
Query: 650 RRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEED 709
R+ + + K E+R DL D++ SE + S S E++EE+EE +
Sbjct: 204 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 263
Query: 710 SSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
S E+ + + E ++ ++ +E+ + ++SED+
Sbjct: 264 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 303
Score = 34.7 bits (78), Expect = 0.33
Identities = 40/162 (24%), Positives = 62/162 (38%), Gaps = 14/162 (8%)
Query: 587 RRQRVSFGVSEQQAVEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKER--LEDLN 644
R+++ V E++ K REE W + + RE+ E S +ER LE L
Sbjct: 71 RKEKKHARVKEKEREHERRKRHREEQDKAR---REWERQKRREMAREHSRRERDRLEQLE 127
Query: 645 FPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEE 704
+ RKM +++ E R+Q E E ER R +S H ++ ++
Sbjct: 128 RKRERERKMREQQKEQREQ-------KERERRAEERRKEREARREVSAHHRTMREDYSDK 180
Query: 705 EGEEDSSNSEDGDPDAEAGLAPGE--LQQLAQGPEDELEDLQ 744
S S P L G +++ D L DLQ
Sbjct: 181 VKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ 222
Score = 33.1 bits (74), Expect = 0.97
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 63 KGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASE 122
K E +D LS L+D K S + S S+ EEEE EE+ E
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 267
Query: 123 EEDGAEEGED 132
EE+ EE E+
Sbjct: 268 EEEEEEEEEE 277
Score = 30.4 bits (67), Expect = 6.3
Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 25 DSESESESENSPQAET---REAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDP 81
DSE ++ S S AE+ E E ++ GS S + E +++ + +
Sbjct: 226 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE- 284
Query: 82 EFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRG 139
+ ++QS S+ + SE+EE + V+ E+ + D E E + V G
Sbjct: 285 ------EASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 336
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 41.6 bits (96), Expect = 0.003
Identities = 23/100 (23%), Positives = 47/100 (47%)
Query: 650 RRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEED 709
R+ + + K E+R DL D++ SE + S S E++EE+EE +
Sbjct: 249 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE 308
Query: 710 SSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
S E+ + + E ++ ++ +E+ + ++SED+
Sbjct: 309 ESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDE 348
Score = 33.1 bits (74), Expect = 0.97
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 11/127 (8%)
Query: 622 WRKLRDREIQLEISGKER--LEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTE 679
W + + RE+ E S +ER LE L + RKM +++ E R+Q E E
Sbjct: 148 WERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ-------KERERRAEE 200
Query: 680 GFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGE--LQQLAQGPE 737
ER R +S H ++ ++ S S P L G +++
Sbjct: 201 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEER 260
Query: 738 DELEDLQ 744
D L DLQ
Sbjct: 261 DLLSDLQ 267
Score = 33.1 bits (74), Expect = 0.97
Identities = 23/70 (32%), Positives = 30/70 (42%)
Query: 63 KGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASE 122
K E +D LS L+D K S + S S+ EEEE EE+ E
Sbjct: 253 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 312
Query: 123 EEDGAEEGED 132
EE+ EE E+
Sbjct: 313 EEEEEEEEEE 322
Score = 30.4 bits (67), Expect = 6.3
Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 10/118 (8%)
Query: 25 DSESESESENSPQAET---REAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDP 81
DSE ++ S S AE+ E E ++ GS S + E +++ + +
Sbjct: 271 DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSE- 329
Query: 82 EFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRG 139
+ ++QS S+ + SE+EE + V+ E+ + D E E + V G
Sbjct: 330 ------EASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 381
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 41.2 bits (95), Expect = 0.004
Identities = 51/194 (26%), Positives = 79/194 (40%), Gaps = 21/194 (10%)
Query: 9 RRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGS-PSASRRKGRAS 67
R LA +DE ++ + +SE + R ++ S D P S S G AS
Sbjct: 365 RSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMAS 424
Query: 68 EHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLE------EAS 121
+ SR + D +++++S + + EEEE + LE E
Sbjct: 425 QGCPSASRAETDD-------EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDD 477
Query: 122 EEEDGAEE---GEDGDRVPRG---LKGKKNSVPVTVAMVERWKQAAKQRL-TPKLFHEVV 174
EEED EE G+DGD+ P + +KN P +Q K R+ +P L E
Sbjct: 478 EEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEP 537
Query: 175 QAFRAAVATTRGDQ 188
A + A + G+Q
Sbjct: 538 LAPSSIDAESNGEQ 551
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 9/103 (8%)
Query: 649 KRRKMADRKDE-DRKQFKDLFDLNSSEEDDT--------EGFSERGILRPLSTRHGVEDD 699
K + D+ +E +RK+ + SS DT EG S S DD
Sbjct: 378 KYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD 437
Query: 700 EEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELED 742
E+DEE EE+ E+ + +A +L+Q+ +G ED+ E+
Sbjct: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 480
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 13/84 (15%)
Query: 654 ADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNS 713
+D ++E+ ++ ++ +S EE+D E E G EDDEE++E EE+++
Sbjct: 443 SDEEEEEEEEEEEEEATDSEEEEDLEQMQE-----------GQEDDEEEDE--EEEAAAG 489
Query: 714 EDGDPDAEAGLAPGELQQLAQGPE 737
+DGD + L + L G +
Sbjct: 490 KDGDKSPMSSLQISNEKNLEPGKQ 513
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 41.2 bits (95), Expect = 0.004
Identities = 51/194 (26%), Positives = 79/194 (40%), Gaps = 21/194 (10%)
Query: 9 RRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGS-PSASRRKGRAS 67
R LA +DE ++ + +SE + R ++ S D P S S G AS
Sbjct: 365 RSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMAS 424
Query: 68 EHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLE------EAS 121
+ SR + D +++++S + + EEEE + LE E
Sbjct: 425 QGCPSASRAETDD-------EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDD 477
Query: 122 EEEDGAEE---GEDGDRVPRG---LKGKKNSVPVTVAMVERWKQAAKQRL-TPKLFHEVV 174
EEED EE G+DGD+ P + +KN P +Q K R+ +P L E
Sbjct: 478 EEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEP 537
Query: 175 QAFRAAVATTRGDQ 188
A + A + G+Q
Sbjct: 538 LAPSSIDAESNGEQ 551
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 9/103 (8%)
Query: 649 KRRKMADRKDE-DRKQFKDLFDLNSSEEDDT--------EGFSERGILRPLSTRHGVEDD 699
K + D+ +E +RK+ + SS DT EG S S DD
Sbjct: 378 KYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD 437
Query: 700 EEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELED 742
E+DEE EE+ E+ + +A +L+Q+ +G ED+ E+
Sbjct: 438 EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 480
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 13/84 (15%)
Query: 654 ADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNS 713
+D ++E+ ++ ++ +S EE+D E E G EDDEE++E EE+++
Sbjct: 443 SDEEEEEEEEEEEEEATDSEEEEDLEQMQE-----------GQEDDEEEDE--EEEAAAG 489
Query: 714 EDGDPDAEAGLAPGELQQLAQGPE 737
+DGD + L + L G +
Sbjct: 490 KDGDKSPMSSLQISNEKNLEPGKQ 513
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 41.2 bits (95), Expect = 0.004
Identities = 51/194 (26%), Positives = 79/194 (40%), Gaps = 21/194 (10%)
Query: 9 RRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGS-PSASRRKGRAS 67
R LA +DE ++ + +SE + R ++ S D P S S G AS
Sbjct: 377 RSLAMSRLDEVISKYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMAS 436
Query: 68 EHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLE------EAS 121
+ SR + D +++++S + + EEEE + LE E
Sbjct: 437 QGCPSASRAETDD-------EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDD 489
Query: 122 EEEDGAEE---GEDGDRVPRG---LKGKKNSVPVTVAMVERWKQAAKQRL-TPKLFHEVV 174
EEED EE G+DGD+ P + +KN P +Q K R+ +P L E
Sbjct: 490 EEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEP 549
Query: 175 QAFRAAVATTRGDQ 188
A + A + G+Q
Sbjct: 550 LAPSSIDAESNGEQ 563
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 9/103 (8%)
Query: 649 KRRKMADRKDE-DRKQFKDLFDLNSSEEDDT--------EGFSERGILRPLSTRHGVEDD 699
K + D+ +E +RK+ + SS DT EG S S DD
Sbjct: 390 KYAMLQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDD 449
Query: 700 EEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELED 742
E+DEE EE+ E+ + +A +L+Q+ +G ED+ E+
Sbjct: 450 EDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEE 492
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/84 (27%), Positives = 42/84 (50%), Gaps = 13/84 (15%)
Query: 654 ADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNS 713
+D ++E+ ++ ++ +S EE+D E E G EDDEE++E EE+++
Sbjct: 455 SDEEEEEEEEEEEEEATDSEEEEDLEQMQE-----------GQEDDEEEDE--EEEAAAG 501
Query: 714 EDGDPDAEAGLAPGELQQLAQGPE 737
+DGD + L + L G +
Sbjct: 502 KDGDKSPMSSLQISNEKNLEPGKQ 525
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 40.8 bits (94), Expect = 0.005
Identities = 25/115 (21%), Positives = 54/115 (46%), Gaps = 14/115 (12%)
Query: 649 KRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSE--RGILRPLSTRHGVEDDEEDEEEG 706
K K A ++D D ++ D + +ED+ E E ++ + ED++++++E
Sbjct: 135 KNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED 194
Query: 707 EEDSSNSEDGDPDAE------------AGLAPGELQQLAQGPEDELEDLQLSEDD 749
+ED + E+ D + E A + P + + +A+ ++E +D +DD
Sbjct: 195 DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD 249
Score = 37.0 bits (84), Expect = 0.067
Identities = 20/72 (27%), Positives = 39/72 (54%), Gaps = 9/72 (12%)
Query: 657 KDEDRKQFKDLFDLNSSEEDDTEGFS---------ERGILRPLSTRHGVEDDEEDEEEGE 707
+DED + +D D + EEDD+E + + + P+ ++ ED++E+E++ +
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244
Query: 708 EDSSNSEDGDPD 719
ED + ED + D
Sbjct: 245 EDDDDDEDDEDD 256
Score = 36.6 bits (83), Expect = 0.088
Identities = 51/226 (22%), Positives = 91/226 (40%), Gaps = 22/226 (9%)
Query: 25 DSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFY 84
DS+ E + ++ E E + +P +A+ ASE +D D D +
Sbjct: 144 DSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAP--ASEDEDDEDDEDDEDDDDD 201
Query: 85 KFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRG----- 139
+ ++++ + P + +V E+ EEED +E +D D
Sbjct: 202 EEDDSEEEAMETTPAKGKKAAKVVPVKA-KNVAEDEDEEEDDEDEDDDDDEDDEDDDDED 260
Query: 140 ---LKGKKNSVPVTVAMVERWKQAAKQRLTPKLFHEVVQ------AFRAAVATTRGDQES 190
+ ++ PV A +R K+ AKQ+ P+ + V+ AF V ++ +
Sbjct: 261 DEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTEPTTAFNLFVGNLNFNKSA 320
Query: 191 AEANKFQVTDSAAFNALVTFCIRDLIGCLQKLLFGKVAKDSSRMLQ 236
E K ++D A N L +R IG +K FG V +S+ L+
Sbjct: 321 PEL-KTGISDVFAKNDLAVVDVR--IGMTRK--FGYVDFESAEDLE 361
Score = 33.1 bits (74), Expect = 0.97
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 20/93 (21%)
Query: 648 IKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGE 707
+K + +A+ +DE+ + D + +EDD + EDDEE+EEE E
Sbjct: 227 VKAKNVAEDEDEEEDDEDEDDDDDEDDEDDDD-----------------EDDEEEEEEEE 269
Query: 708 EDSSNSEDGDPDAEAG---LAPGELQQLAQGPE 737
E+ G E AP +Q +G E
Sbjct: 270 EEPVKEAPGKRKKEMAKQKAAPEAKKQKVEGTE 302
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/95 (24%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Query: 655 DRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSE 714
D++D + ++ D + E+D+ E +E G E++E+++E+ +ED + SE
Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 208
Query: 715 DGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
G+ + E GL+ +++ Q ED+ + ++ E++
Sbjct: 209 LGEGEEEVGLS-YLMKEEIQDEEDDDDYVEEGEEE 242
Score = 35.0 bits (79), Expect = 0.25
Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 24/121 (19%)
Query: 25 DSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFY 84
DSE E + + E E EA G P + E +D+ D D
Sbjct: 157 DSEEEDDEDGDEDDEEEEENEA--------GPPEGYEEEEEEEEEEDE-----DED---- 199
Query: 85 KFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPR-GLKGK 143
++ D++ S+ EEE G + + + +++ +++D EEGE+ + GL+G+
Sbjct: 200 ---EDEDEA---GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 253
Query: 144 K 144
K
Sbjct: 254 K 254
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 14/124 (11%)
Query: 624 KLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSE 683
K++D + + L+ L+ + + D ++ + + + L+ +++D E
Sbjct: 99 KIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEA--- 155
Query: 684 RGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDL 743
P S ED +ED+EE EE+ + +G + E E ++ EDE ED
Sbjct: 156 -----PDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE------EEEEEEDEDEDEDEDE 204
Query: 744 QLSE 747
SE
Sbjct: 205 AGSE 208
Score = 32.0 bits (71), Expect = 2.2
Identities = 24/116 (20%), Positives = 50/116 (43%), Gaps = 5/116 (4%)
Query: 23 GFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPE 82
GFD E ++E+ +S + + + E ++ P + E ++ +D D
Sbjct: 147 GFDQE-DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 205
Query: 83 FYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPR 138
+ + ++ L++ + ++EE D +EE EEE+ E G G++ R
Sbjct: 206 GSELGEGEEEVGLSYLMKEEIQDEEDD----DDYVEEGEEEEEEEEGGLRGEKRKR 257
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/95 (24%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Query: 655 DRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSE 714
D++D + ++ D + E+D+ E +E G E++E+++E+ +ED + SE
Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 167
Query: 715 DGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
G+ + E GL+ +++ Q ED+ + ++ E++
Sbjct: 168 LGEGEEEVGLS-YLMKEEIQDEEDDDDYVEEGEEE 201
Score = 35.0 bits (79), Expect = 0.25
Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 24/121 (19%)
Query: 25 DSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFY 84
DSE E + + E E EA G P + E +D+ D D
Sbjct: 116 DSEEEDDEDGDEDDEEEEENEA--------GPPEGYEEEEEEEEEEDE-----DED---- 158
Query: 85 KFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPR-GLKGK 143
++ D++ S+ EEE G + + + +++ +++D EEGE+ + GL+G+
Sbjct: 159 ---EDEDEA---GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 212
Query: 144 K 144
K
Sbjct: 213 K 213
Score = 32.3 bits (72), Expect = 1.7
Identities = 33/124 (26%), Positives = 55/124 (44%), Gaps = 16/124 (12%)
Query: 632 LEISGKERLEDLNFPEIKRRKMADRKDED--RKQFKDLFDLNSS------EEDDTEGFSE 683
+E+S RL LN +++++ + + K D + +L D S + +GF +
Sbjct: 52 VELSSLARLPSLN--KLRKQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQ 109
Query: 684 RGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDL 743
P S ED +ED+EE EE+ + +G + E E ++ EDE ED
Sbjct: 110 EDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE------EEEEEEDEDEDEDEDE 163
Query: 744 QLSE 747
SE
Sbjct: 164 AGSE 167
Score = 32.0 bits (71), Expect = 2.2
Identities = 24/116 (20%), Positives = 50/116 (43%), Gaps = 5/116 (4%)
Query: 23 GFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPE 82
GFD E ++E+ +S + + + E ++ P + E ++ +D D
Sbjct: 106 GFDQE-DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 164
Query: 83 FYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPR 138
+ + ++ L++ + ++EE D +EE EEE+ E G G++ R
Sbjct: 165 GSELGEGEEEVGLSYLMKEEIQDEEDD----DDYVEEGEEEEEEEEGGLRGEKRKR 216
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/95 (24%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Query: 655 DRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSE 714
D++D + ++ D + E+D+ E +E G E++E+++E+ +ED + SE
Sbjct: 101 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSE 160
Query: 715 DGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD 749
G+ + E GL+ +++ Q ED+ + ++ E++
Sbjct: 161 LGEGEEEVGLS-YLMKEEIQDEEDDDDYVEEGEEE 194
Score = 35.0 bits (79), Expect = 0.25
Identities = 29/121 (23%), Positives = 52/121 (42%), Gaps = 24/121 (19%)
Query: 25 DSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFY 84
DSE E + + E E EA G P + E +D+ D D
Sbjct: 109 DSEEEDDEDGDEDDEEEEENEA--------GPPEGYEEEEEEEEEEDE-----DED---- 151
Query: 85 KFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPR-GLKGK 143
++ D++ S+ EEE G + + + +++ +++D EEGE+ + GL+G+
Sbjct: 152 ---EDEDEA---GSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGE 205
Query: 144 K 144
K
Sbjct: 206 K 206
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/124 (22%), Positives = 53/124 (42%), Gaps = 14/124 (11%)
Query: 624 KLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSE 683
K++D + + L+ L+ + + D ++ + + + L+ +++D E
Sbjct: 51 KIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEA--- 107
Query: 684 RGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDL 743
P S ED +ED+EE EE+ + +G + E E ++ EDE ED
Sbjct: 108 -----PDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEE------EEEEEEDEDEDEDEDE 156
Query: 744 QLSE 747
SE
Sbjct: 157 AGSE 160
Score = 32.0 bits (71), Expect = 2.2
Identities = 24/116 (20%), Positives = 50/116 (43%), Gaps = 5/116 (4%)
Query: 23 GFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPE 82
GFD E ++E+ +S + + + E ++ P + E ++ +D D
Sbjct: 99 GFDQE-DNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEA 157
Query: 83 FYKFLQENDQSLLNFSDSDSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPR 138
+ + ++ L++ + ++EE D +EE EEE+ E G G++ R
Sbjct: 158 GSELGEGEEEVGLSYLMKEEIQDEEDD----DDYVEEGEEEEEEEEGGLRGEKRKR 209
>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
Length = 7081
Score = 40.4 bits (93), Expect = 0.006
Identities = 28/93 (30%), Positives = 41/93 (44%), Gaps = 5/93 (5%)
Query: 649 KRRKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEE 708
K + +K+ED + DL E+ D +G PL+ + + D E +E+G+E
Sbjct: 4330 KAKDYMQQKEEDEVKISAEKDLMHPEDKDLKGKKALSQNLPLNPKEPGKRDGEGQEQGKE 4389
Query: 709 DSSNSEDGDPDAEAGLAPGELQQLAQGPEDELE 741
D E G+ D E E QQ A G E E
Sbjct: 4390 DGEGEEQGNRDGET-----EEQQQADGVGTEQE 4417
Score = 36.2 bits (82), Expect = 0.11
Identities = 34/141 (24%), Positives = 59/141 (41%), Gaps = 9/141 (6%)
Query: 613 TPLTLYY----SHWRKLRDREIQLEISGKERLEDLNFPEIKRRKMADRKDEDRKQFKDLF 668
T +T YY SH + E + G D+ K + +K++D +
Sbjct: 4110 TEITRYYLPELSHQKSSEAGE---KADGVASKGDITIKVQKAKDYMQQKEDDEVKISAKK 4166
Query: 669 DLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAE-AGLAPG 727
D+ E+ + PL+T+ + D+E +E+G+ED E G D AG
Sbjct: 4167 DIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGKEDRRGAGQEKV 4226
Query: 728 ELQQLAQGPED-ELEDLQLSE 747
+ + QG D E+E+ Q ++
Sbjct: 4227 DREDKEQGKMDHEVEEQQKAD 4247
>gi|27597090 suppressor of Ty 6 homolog [Homo sapiens]
Length = 1726
Score = 40.0 bits (92), Expect = 0.008
Identities = 26/80 (32%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
Query: 670 LNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDPDAEAGLAPGEL 729
+ S E+ E +++ G + P T+ VE++++DEEE EE N +D D +
Sbjct: 5 VESEAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEE---NLDDQDEQGNLKGFINDD 61
Query: 730 QQLAQGPEDELEDLQLSEDD 749
+G EDE D SEDD
Sbjct: 62 DDEDEGEEDEGSDSGDSEDD 81
Score = 35.4 bits (80), Expect = 0.20
Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 17/73 (23%)
Query: 651 RKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDEEDEEEGEEDS 710
+K + +D+D ++ EE++ + E+G L+ G +D++DE+EGEED
Sbjct: 28 KKFVEEEDDDEEE----------EEENLDDQDEQGNLK------GFINDDDDEDEGEEDE 71
Query: 711 SNSEDGDPDAEAG 723
S+ GD + + G
Sbjct: 72 G-SDSGDSEDDVG 83
Score = 30.0 bits (66), Expect = 8.2
Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 22/101 (21%)
Query: 638 ERLEDLNFP--------EIKR-------RKMADRKDEDRKQF-KDLFDLNS-SEEDDTEG 680
+RLED +F ++KR +KM+D +D+D +++ K+ + + +EE +G
Sbjct: 94 DRLEDDDFDLIEENLGVKVKRGQKYRRVKKMSDDEDDDEEEYGKEEHEKEAIAEEIFQDG 153
Query: 681 FSERG---ILRPLSTRHGVEDDEEDEEEGEEDSSNSEDGDP 718
E G + P++ E++E+DEE +D +DG P
Sbjct: 154 EGEEGQEAMEAPMAPPE--EEEEDDEESDIDDFIVDDDGQP 192
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,821,589
Number of Sequences: 37866
Number of extensions: 1365455
Number of successful extensions: 16756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 320
Number of HSP's that attempted gapping in prelim test: 11012
Number of HSP's gapped (non-prelim): 3344
length of query: 749
length of database: 18,247,518
effective HSP length: 110
effective length of query: 639
effective length of database: 14,082,258
effective search space: 8998562862
effective search space used: 8998562862
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.