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Search of human proteins with 157388939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|157388939 WD repeat domain, phosphoinositide interacting 1
[Homo sapiens]
(446 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|157388939 WD repeat domain, phosphoinositide interacting 1 [H... 889 0.0
gi|54111428 WD repeat domain, phosphoinositide interacting 2 iso... 484 e-137
gi|75677331 WD repeat domain, phosphoinositide interacting 2 iso... 480 e-135
gi|7661580 WD repeat domain, phosphoinositide interacting 2 isof... 474 e-134
gi|75677329 WD repeat domain, phosphoinositide interacting 2 iso... 470 e-132
gi|75677340 WD repeat domain, phosphoinositide interacting 2 iso... 438 e-123
gi|122939167 WDR45-like [Homo sapiens] 128 1e-29
gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens] 114 2e-25
gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens] 110 2e-24
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 45 1e-04
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 43 5e-04
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 43 5e-04
gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo ... 40 0.006
gi|8923881 WD SOCS-box protein 2 [Homo sapiens] 37 0.036
gi|21071067 TBP-associated factor 5 [Homo sapiens] 37 0.047
gi|32189425 WD repeat domain 69 [Homo sapiens] 37 0.047
gi|22749037 WD repeat domain 65 [Homo sapiens] 36 0.062
gi|206597470 neural precursor cell expressed, developmentally do... 36 0.081
gi|206597468 neural precursor cell expressed, developmentally do... 36 0.081
gi|23097254 neural precursor cell expressed, developmentally dow... 36 0.081
gi|206597465 neural precursor cell expressed, developmentally do... 36 0.081
gi|16554629 WD repeat domain 5 [Homo sapiens] 35 0.14
gi|16554627 WD repeat domain 5 [Homo sapiens] 35 0.14
gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Ho... 34 0.24
gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Ho... 34 0.24
gi|23199987 WD repeat domain 5B [Homo sapiens] 34 0.24
gi|75709220 cleavage stimulation factor subunit 1 [Homo sapiens] 34 0.31
gi|4557491 cleavage stimulation factor subunit 1 [Homo sapiens] 34 0.31
gi|75709217 cleavage stimulation factor subunit 1 [Homo sapiens] 34 0.31
gi|157266266 WD repeat domain 86 [Homo sapiens] 34 0.31
>gi|157388939 WD repeat domain, phosphoinositide interacting 1 [Homo
sapiens]
Length = 446
Score = 889 bits (2297), Expect = 0.0
Identities = 446/446 (100%), Positives = 446/446 (100%)
Query: 1 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDV 60
MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDV
Sbjct: 1 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDV 60
Query: 61 YIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES 120
YIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES
Sbjct: 61 YIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES 120
Query: 121 IYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVC 180
IYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVC
Sbjct: 121 IYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVC 180
Query: 181 TIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVF 240
TIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVF
Sbjct: 181 TIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVF 240
Query: 241 SMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQ 300
SMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQ
Sbjct: 241 SMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQ 300
Query: 301 DRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLL 360
DRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLL
Sbjct: 301 DRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLL 360
Query: 361 GSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGP 420
GSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGP
Sbjct: 361 GSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGP 420
Query: 421 VCLDDENEFPPIILCRGNQKGKTKQS 446
VCLDDENEFPPIILCRGNQKGKTKQS
Sbjct: 421 VCLDDENEFPPIILCRGNQKGKTKQS 446
>gi|54111428 WD repeat domain, phosphoinositide interacting 2
isoform b [Homo sapiens]
Length = 436
Score = 484 bits (1245), Expect = e-137
Identities = 247/418 (59%), Positives = 320/418 (76%), Gaps = 7/418 (1%)
Query: 21 SFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKP 80
+FNQD TSLA G+K+GYK FSLSSV++L+Q++ + DV IVERLFSSSLV +VS P
Sbjct: 19 NFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAP 78
Query: 81 RQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPA 140
R++ V HFKKGTEICNYSYS+ IL+++LNRQRL+VCLEES+YIHNI+DMK+L T+ + P
Sbjct: 79 RKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP 138
Query: 141 NPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSK 200
NP GLCALSIN+ N YLAYPGS T GE+ ++D +L+ I AH+ LAA+ F+ASG+K
Sbjct: 139 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 198
Query: 201 LASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFK 260
LA+ASEKGTVIRVFS+P+GQKL+EFRRG+KR V+I SL FSMD FL ASSNTETVHIFK
Sbjct: 199 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 258
Query: 261 LEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTL 320
LE V PEEP+TW+GY GK+ MA+T+YLP+QV++M +Q RAFAT RL F G +NIC+L
Sbjct: 259 LETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSL 318
Query: 321 STIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGS-GTTEENKENDLR--PSL 377
+TIQK+PRLLV ++ G+LYMYNLDPQ+GGEC L+K H L GS TT E ++ P +
Sbjct: 319 ATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLV 378
Query: 378 PQSYAATVARPS-ASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIIL 434
Q+Y A + + S+ T Y++D GA+ G + + A + LD+++E PP+IL
Sbjct: 379 TQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASA---LRLDEDSEHPPMIL 433
>gi|75677331 WD repeat domain, phosphoinositide interacting 2
isoform d [Homo sapiens]
Length = 425
Score = 480 bits (1235), Expect = e-135
Identities = 245/417 (58%), Positives = 316/417 (75%), Gaps = 16/417 (3%)
Query: 21 SFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKP 80
+FNQD TSLA G+K+GYK FSLSSV++L+Q++ + DV IVERLFSSSLV +VS P
Sbjct: 19 NFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAP 78
Query: 81 RQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPA 140
R++ V HFKKGTEICNYSYS+ IL+++LNRQRL+VCLEES+YIHNI+DMK+L T+ + P
Sbjct: 79 RKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP 138
Query: 141 NPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSK 200
NP GLCALSIN+ N YLAYPGS T GE+ ++D +L+ I AH+ LAA+ F+ASG+K
Sbjct: 139 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 198
Query: 201 LASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFK 260
LA+ASEKGTVIRVFS+P+GQKL+EFRRG+KR V+I SL FSMD FL ASSNTETVHIFK
Sbjct: 199 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 258
Query: 261 LEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTL 320
LE V PEEP+TW+GY GK+ MA+T+YLP+QV++M +Q RAFAT RL F G +NIC+L
Sbjct: 259 LETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSL 318
Query: 321 STIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGS-GTTEENKENDLR--PSL 377
+TIQK+PRLLV ++ G+LYMYNLDPQ+GGEC L+K H L GS TT E ++ P +
Sbjct: 319 ATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLV 378
Query: 378 PQSYAATVARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIIL 434
Q+Y A + Y++D GA+ G + + A + LD+++E PP+IL
Sbjct: 379 TQTYGAAAGK----------AYTDDLGAVGGACLEDEASA---LRLDEDSEHPPMIL 422
>gi|7661580 WD repeat domain, phosphoinositide interacting 2 isoform
a [Homo sapiens]
Length = 454
Score = 474 bits (1219), Expect = e-134
Identities = 242/411 (58%), Positives = 314/411 (76%), Gaps = 7/411 (1%)
Query: 28 SLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYH 87
SLA G+K+GYK FSLSSV++L+Q++ + DV IVERLFSSSLV +VS PR++ V H
Sbjct: 44 SLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCH 103
Query: 88 FKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCA 147
FKKGTEICNYSYS+ IL+++LNRQRL+VCLEES+YIHNI+DMK+L T+ + P NP GLCA
Sbjct: 104 FKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCA 163
Query: 148 LSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEK 207
LSIN+ N YLAYPGS T GE+ ++D +L+ I AH+ LAA+ F+ASG+KLA+ASEK
Sbjct: 164 LSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEK 223
Query: 208 GTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNS 267
GTVIRVFS+P+GQKL+EFRRG+KR V+I SL FSMD FL ASSNTETVHIFKLE V
Sbjct: 224 GTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEK 283
Query: 268 RPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLP 327
PEEP+TW+GY GK+ MA+T+YLP+QV++M +Q RAFAT RL F G +NIC+L+TIQK+P
Sbjct: 284 PPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIP 343
Query: 328 RLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGS-GTTEENKENDLR--PSLPQSYAAT 384
RLLV ++ G+LYMYNLDPQ+GGEC L+K H L GS TT E ++ P + Q+Y A
Sbjct: 344 RLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAA 403
Query: 385 VARPS-ASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIIL 434
+ + S+ T Y++D GA+ G + + A + LD+++E PP+IL
Sbjct: 404 AGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASA---LRLDEDSEHPPMIL 451
>gi|75677329 WD repeat domain, phosphoinositide interacting 2
isoform c [Homo sapiens]
Length = 443
Score = 470 bits (1209), Expect = e-132
Identities = 240/410 (58%), Positives = 310/410 (75%), Gaps = 16/410 (3%)
Query: 28 SLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYH 87
SLA G+K+GYK FSLSSV++L+Q++ + DV IVERLFSSSLV +VS PR++ V H
Sbjct: 44 SLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCH 103
Query: 88 FKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCA 147
FKKGTEICNYSYS+ IL+++LNRQRL+VCLEES+YIHNI+DMK+L T+ + P NP GLCA
Sbjct: 104 FKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCA 163
Query: 148 LSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEK 207
LSIN+ N YLAYPGS T GE+ ++D +L+ I AH+ LAA+ F+ASG+KLA+ASEK
Sbjct: 164 LSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEK 223
Query: 208 GTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNS 267
GTVIRVFS+P+GQKL+EFRRG+KR V+I SL FSMD FL ASSNTETVHIFKLE V
Sbjct: 224 GTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEK 283
Query: 268 RPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLP 327
PEEP+TW+GY GK+ MA+T+YLP+QV++M +Q RAFAT RL F G +NIC+L+TIQK+P
Sbjct: 284 PPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIP 343
Query: 328 RLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGS-GTTEENKENDLR--PSLPQSYAAT 384
RLLV ++ G+LYMYNLDPQ+GGEC L+K H L GS TT E ++ P + Q+Y A
Sbjct: 344 RLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAA 403
Query: 385 VARPSASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIIL 434
+ Y++D GA+ G + + A + LD+++E PP+IL
Sbjct: 404 AGK----------AYTDDLGAVGGACLEDEASA---LRLDEDSEHPPMIL 440
>gi|75677340 WD repeat domain, phosphoinositide interacting 2
isoform e [Homo sapiens]
Length = 384
Score = 438 bits (1126), Expect = e-123
Identities = 225/384 (58%), Positives = 288/384 (75%), Gaps = 16/384 (4%)
Query: 54 SNEIPDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRL 113
S + DV IVERLFSSSLV +VS PR++ V HFKKGTEICNYSYS+ IL+++LNRQRL
Sbjct: 11 SADTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRL 70
Query: 114 LVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDG 173
+VCLEES+YIHNI+DMK+L T+ + P NP GLCALSIN+ N YLAYPGS T GE+ ++D
Sbjct: 71 IVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDT 130
Query: 174 NSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYV 233
+L+ I AH+ LAA+ F+ASG+KLA+ASEKGTVIRVFS+P+GQKL+EFRRG+KR V
Sbjct: 131 INLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCV 190
Query: 234 TISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQ 293
+I SL FSMD FL ASSNTETVHIFKLE V PEEP+TW+GY GK+ MA+T+YLP+Q
Sbjct: 191 SICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQ 250
Query: 294 VSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVL 353
V++M +Q RAFAT RL F G +NIC+L+TIQK+PRLLV ++ G+LYMYNLDPQ+GGEC L
Sbjct: 251 VTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECAL 310
Query: 354 IKTHSLLGS-GTTEENKENDLR--PSLPQSYAATVARPSASSASTVPGYSEDGGALRGEV 410
+K H L GS TT E ++ P + Q+Y A + Y++D GA+ G
Sbjct: 311 MKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK----------AYTDDLGAVGGAC 360
Query: 411 IPEHEFATGPVCLDDENEFPPIIL 434
+ + A + LD+++E PP+IL
Sbjct: 361 LEDEASA---LRLDEDSEHPPMIL 381
>gi|122939167 WDR45-like [Homo sapiens]
Length = 344
Score = 128 bits (321), Expect = 1e-29
Identities = 98/344 (28%), Positives = 164/344 (47%), Gaps = 45/344 (13%)
Query: 22 FNQDCTSLATGTKAGYKLFS---LSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHT 78
FNQD A G + G+++++ L E+ + + G V VE LF + + +V
Sbjct: 18 FNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGG-----VGHVEMLFRCNYLALVGGG 72
Query: 79 K-----PRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESI----YIHNIKDM 129
K P ++ ++ K + +S+ + +++L R R++V L+ I + HN +
Sbjct: 73 KKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQL 132
Query: 130 KLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYD-GNSLKTVCTIAAHEGT 188
+ +T NP GLC L N +NS LA+PG+ T G + L D ++ K I AHEG
Sbjct: 133 HVFETCY----NPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGV 187
Query: 189 LAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLC 248
L+ I N G+++A+ASEKGT+IR+F G + E RRG + I + F+ D+ +C
Sbjct: 188 LSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG-SQAANIYCINFNQDASLIC 246
Query: 249 ASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATAR 308
SS+ TVHIF E ++ ++ + ++ K F + ++ QV
Sbjct: 247 VSSDHGTVHIFAAEDPKRNKQSSLAS-ASFLPKYFSSKWSFSKFQVP------------- 292
Query: 309 LNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECV 352
SG IC T + A S + +++N GEC+
Sbjct: 293 ---SGSPCICAFGTEPNAVIAICADGSYYKFLFN----PKGECI 329
Score = 32.0 bits (71), Expect = 1.2
Identities = 19/81 (23%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 1 MEAEAADAPPGGV---ESALSCFSFNQDCTSLATGTKAG--YKLFSLSSVEQLDQVHGSN 55
++ + + PP + E LSC + N T +AT ++ G ++F SS + ++ +
Sbjct: 169 VDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGS 228
Query: 56 EIPDVYIVERLFSSSLVVVVS 76
+ ++Y + +SL+ V S
Sbjct: 229 QAANIYCINFNQDASLICVSS 249
>gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens]
Length = 360
Score = 114 bits (285), Expect = 2e-25
Identities = 80/264 (30%), Positives = 136/264 (51%), Gaps = 21/264 (7%)
Query: 22 FNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNE-IPDVYIVERLFSSSLVVVV---SH 77
FNQD + + G +++++ + +++ H +E + + +VE L S+L+ +V S
Sbjct: 14 FNQDQSCFCCAMETGVRIYNVEPL--MEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSS 71
Query: 78 TKPRQMNVYHFKKGTE--------ICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDM 129
K +++V + E + ++++ +LS+R+ ++++ L+ IY+++ D
Sbjct: 72 PKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDN 131
Query: 130 KLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK-----TVCTIAA 184
D NP GLC L + L +PG G + L D S K TI A
Sbjct: 132 PRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGH-KCGSLQLVDLASTKPGTSSAPFTINA 190
Query: 185 HEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDS 244
H+ +A ++ N G+ +ASAS+KGT+IR+F +KL E RRG T+ + FS DS
Sbjct: 191 HQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDP-ATLYCINFSHDS 249
Query: 245 QFLCASSNTETVHIFKLEQVTNSR 268
FLCASS+ TVHIF L+ +R
Sbjct: 250 SFLCASSDKGTVHIFALKDTRLNR 273
>gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens]
Length = 361
Score = 110 bits (276), Expect = 2e-24
Identities = 78/265 (29%), Positives = 133/265 (50%), Gaps = 22/265 (8%)
Query: 22 FNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNE-IPDVYIVERLFSSSLVVVVSH-TK 79
FNQD + + G +++++ + +++ H +E + + +VE L S+L+ +V +
Sbjct: 14 FNQDQSCFCCAMETGVRIYNVEPL--MEKGHLDHEQVGSMGLVEMLHRSNLLALVGGGSS 71
Query: 80 PRQMNVYHF-----------KKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKD 128
P+ + K + ++++ +LS+R+ ++++ L+ IY+++ D
Sbjct: 72 PKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPD 131
Query: 129 MKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK-----TVCTIA 183
D NP GLC L + L +PG G + L D S K TI
Sbjct: 132 NPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGH-KCGSLQLVDLASTKPGTSSAPFTIN 190
Query: 184 AHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMD 243
AH+ +A ++ N G+ +ASAS+KGT+IR+F +KL E RRG T+ + FS D
Sbjct: 191 AHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDP-ATLYCINFSHD 249
Query: 244 SQFLCASSNTETVHIFKLEQVTNSR 268
S FLCASS+ TVHIF L+ +R
Sbjct: 250 SSFLCASSDKGTVHIFALKDTRLNR 274
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 2/109 (1%)
Query: 163 LTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKL 222
L +G I ++D + K + + H + +TF GS + ++ + +RV+ + D +
Sbjct: 147 LNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNM 206
Query: 223 YEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEE 271
+ RG + +V S FS DS LC+ ++ V ++ +++ T R E
Sbjct: 207 MKVLRGHQNWV--YSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 253
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 43.1 bits (100), Expect = 5e-04
Identities = 47/197 (23%), Positives = 92/197 (46%), Gaps = 15/197 (7%)
Query: 82 QMNVYHFKKGTEICNYS-YSSNILSIRLNRQRLLVCL---EESIYIHNIKDMKLLKTLLD 137
++N++ K I + + ++S + S+RLN L+ SI + +++ K+L+TL+
Sbjct: 44 RVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMG 103
Query: 138 IPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNAS 197
AN +C+L + ++A T+ I L+D V H + + F+
Sbjct: 104 HKAN---ICSLDFHPYGEFVASGSQDTN--IKLWDIRRKGCVFRYRGHSQAVRCLRFSPD 158
Query: 198 GSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVH 257
G LASA++ TV +++ + G+ + EF ++ + F + L + S+ T+
Sbjct: 159 GKWLASAADDHTV-KLWDLTAGKMMSEF---PGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
Query: 258 IFKLE--QVTNSRPEEP 272
+ LE QV + EP
Sbjct: 215 FWDLEKFQVVSCIEGEP 231
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 43.1 bits (100), Expect = 5e-04
Identities = 41/154 (26%), Positives = 70/154 (45%), Gaps = 15/154 (9%)
Query: 152 HSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVI 211
H NS GS T + L+ +V H G + ++ F+ +G LASA E +
Sbjct: 435 HPNSNYLATGS-TDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQR-L 492
Query: 212 RVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEE 271
+++ + G LY+ RG +T SL FS DS + ++S +V ++ + S P +
Sbjct: 493 KLWDLASG-TLYKELRGHTDNIT--SLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPAD 549
Query: 272 PST------WSGYMGKM----FMAATNYLPTQVS 295
S+ ++G M + FMA L T ++
Sbjct: 550 GSSSELVGVYTGQMSNVLSVQFMACNLLLVTGIT 583
>gi|20143912 WD repeat and SOCS box-containing 1 isoform 2 [Homo
sapiens]
Length = 275
Score = 39.7 bits (91), Expect = 0.006
Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 2/95 (2%)
Query: 177 KTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTIS 236
K + + H + +TF GS + ++ + +RV+ + D + + RG + +V
Sbjct: 15 KLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWV--Y 72
Query: 237 SLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEE 271
S FS DS LC+ ++ V ++ +++ T R E
Sbjct: 73 SCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 107
>gi|8923881 WD SOCS-box protein 2 [Homo sapiens]
Length = 404
Score = 37.0 bits (84), Expect = 0.036
Identities = 23/117 (19%), Positives = 55/117 (47%), Gaps = 2/117 (1%)
Query: 155 SYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVF 214
S L L G+I +++ + + ++ H+ + ++F SGS + ++ + +R++
Sbjct: 122 SCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIW 181
Query: 215 SVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEE 271
+ K + G ++V S+ S D LC+++ ++V ++ + T R E
Sbjct: 182 DLNKHGKQIQVLSGHLQWVYCCSI--SPDCSMLCSAAGEKSVFLWSMRSYTLIRKLE 236
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 36.6 bits (83), Expect = 0.047
Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 5/108 (4%)
Query: 152 HSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVI 211
H NS GS + L+D + V H+G + ++TF+ +G LA+ + G V+
Sbjct: 636 HPNSNYVATGS-ADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVL 694
Query: 212 RVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIF 259
++ + G + E + T+ SL FS D + L + S TV ++
Sbjct: 695 -LWDIGHGLMVGELKGHTD---TVCSLRFSRDGEILASGSMDNTVRLW 738
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 36.6 bits (83), Expect = 0.047
Identities = 47/251 (18%), Positives = 98/251 (39%), Gaps = 12/251 (4%)
Query: 12 GVESALSCFSFNQDCTSLATGTK-AGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSS 70
G + + C SFN T +ATG+ KL+ + + E++ + G + I+ F++S
Sbjct: 175 GHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS----AEIISLSFNTS 230
Query: 71 LVVVVSHTKPRQMNVYHFKKGTEI-CNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDM 129
+++ + + V+ G ++ + + I S N L+ + D
Sbjct: 231 GDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDA 290
Query: 130 KLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTL 189
K + + + + +++ +A + G ++ + K + + HEG +
Sbjct: 291 TNGKCVATLTGHDDEILDSCFDYTGKLIATASA--DGTARIFSAATRKCIAKLEGHEGEI 348
Query: 190 AAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCA 249
+ I+FN G+ L + S T R++ GQ L I S F+ +
Sbjct: 349 SKISFNPQGNHLLTGSSDKTA-RIWDAQTGQCLQVLEGHTDE---IFSCAFNYKGNIVIT 404
Query: 250 SSNTETVHIFK 260
S T I++
Sbjct: 405 GSKDNTCRIWR 415
Score = 33.1 bits (74), Expect = 0.52
Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 9/120 (7%)
Query: 170 LYDGNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGM 229
L+D + K V T+ H+ + F+ +G +A+AS GT R+FS + + +
Sbjct: 287 LWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTA-RIFSAATRKCIAKLE--- 342
Query: 230 KRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNY 289
IS + F+ L S+ +T I+ + + E G+ ++F A NY
Sbjct: 343 GHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLE-----GHTDEIFSCAFNY 397
Score = 30.4 bits (67), Expect = 3.4
Identities = 38/170 (22%), Positives = 70/170 (41%), Gaps = 26/170 (15%)
Query: 124 HNIKDMKLLKT----LLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTV 179
H K+LK L ++ N +G C ++ ++ + L+D S + +
Sbjct: 80 HTFYLFKVLKAHILPLTNVALNKSGSCFITGSYDRT------------CKLWDTASGEEL 127
Query: 180 CTIAAHEGTLAAITF-NASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSL 238
T+ H + AI F N G K+A+ S T +++SV G+ + FR V +S
Sbjct: 128 NTLEGHRNVVYAIAFNNPYGDKIATGSFDKT-CKLWSVETGKCYHTFRGHTAEIVCLS-- 184
Query: 239 VFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATN 288
F+ S + S T ++ ++ EE T G+ ++ + N
Sbjct: 185 -FNPQSTLVATGSMDTTAKLWDIQ-----NGEEVYTLRGHSAEIISLSFN 228
>gi|22749037 WD repeat domain 65 [Homo sapiens]
Length = 698
Score = 36.2 bits (82), Expect = 0.062
Identities = 41/203 (20%), Positives = 82/203 (40%), Gaps = 22/203 (10%)
Query: 19 CFSFNQDCTSLATGTKAGYKL-FSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSH 77
CFS +++ +T Y + SL+ + + + H Y++ L S+ + + +
Sbjct: 345 CFSPSEETLVASTSKNQLYSITMSLTEISKGEPAHFE------YLMYPLHSAPITGLATC 398
Query: 78 TKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEES---IYIHNIKDMKLLKT 134
+ + + + NY ++ L + + L S I + ++L+
Sbjct: 399 IRKPLIATCSLDRSIRLWNYETNTLELFKEYQEEAYSISLHPSGHFIVVGFADKLRLMNL 458
Query: 135 LLD-------IPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEG 187
L+D G C+ S N + + A G++ I +Y SL+ + ++ H G
Sbjct: 459 LIDDIRSFKEYSVRGCGECSFS-NGGHLFAAVNGNV----IHVYTTTSLENISSLKGHTG 513
Query: 188 TLAAITFNASGSKLASASEKGTV 210
+ +I +NA SKL S G V
Sbjct: 514 KIRSIVWNADDSKLISGGTDGAV 536
>gi|206597470 neural precursor cell expressed, developmentally
down-regulated 1 isoform c [Homo sapiens]
Length = 571
Score = 35.8 bits (81), Expect = 0.081
Identities = 50/207 (24%), Positives = 91/207 (43%), Gaps = 30/207 (14%)
Query: 17 LSCFSFNQDCTSLATGTKAGYKLFS--LSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVV 74
++C ++N + +A+G+ +G + +++ HGSN+ ++ LF SL+
Sbjct: 33 VTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVR-HLKYSLFKKSLLGS 91
Query: 75 VS------------HTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIY 122
VS + + H + IC +S + +L + + L++ I
Sbjct: 92 VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGIC-FSPVNELLFVTIG-------LDKRII 143
Query: 123 IHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKT-VCT 181
+++ KL+KTL+ T L A+ + LA S G+I YD LK+ V T
Sbjct: 144 LYDTSSKKLVKTLVA----DTPLTAVDFMPDGATLAIGSS--RGKIYQYDLRMLKSPVKT 197
Query: 182 IAAHEGTLAAITFNASGSKLASASEKG 208
I+AH+ ++ I F S S+ KG
Sbjct: 198 ISAHKTSVQCIAFQYSTVLTKSSLNKG 224
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 140 ANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGS 199
A +G+C +N L + I+LYD +S K V T+ A + L A+ F G+
Sbjct: 118 APASGICFSPVNE----LLFVTIGLDKRIILYDTSSKKLVKTLVA-DTPLTAVDFMPDGA 172
Query: 200 KLASASEKGTV 210
LA S +G +
Sbjct: 173 TLAIGSSRGKI 183
>gi|206597468 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 35.8 bits (81), Expect = 0.081
Identities = 50/207 (24%), Positives = 91/207 (43%), Gaps = 30/207 (14%)
Query: 17 LSCFSFNQDCTSLATGTKAGYKLFS--LSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVV 74
++C ++N + +A+G+ +G + +++ HGSN+ ++ LF SL+
Sbjct: 122 VTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVR-HLKYSLFKKSLLGS 180
Query: 75 VS------------HTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIY 122
VS + + H + IC +S + +L + + L++ I
Sbjct: 181 VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGIC-FSPVNELLFVTIG-------LDKRII 232
Query: 123 IHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKT-VCT 181
+++ KL+KTL+ T L A+ + LA S G+I YD LK+ V T
Sbjct: 233 LYDTSSKKLVKTLVA----DTPLTAVDFMPDGATLAIGSS--RGKIYQYDLRMLKSPVKT 286
Query: 182 IAAHEGTLAAITFNASGSKLASASEKG 208
I+AH+ ++ I F S S+ KG
Sbjct: 287 ISAHKTSVQCIAFQYSTVLTKSSLNKG 313
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 140 ANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGS 199
A +G+C +N L + I+LYD +S K V T+ A + L A+ F G+
Sbjct: 207 APASGICFSPVNE----LLFVTIGLDKRIILYDTSSKKLVKTLVA-DTPLTAVDFMPDGA 261
Query: 200 KLASASEKGTV 210
LA S +G +
Sbjct: 262 TLAIGSSRGKI 272
>gi|23097254 neural precursor cell expressed, developmentally
down-regulated 1 isoform b [Homo sapiens]
Length = 660
Score = 35.8 bits (81), Expect = 0.081
Identities = 50/207 (24%), Positives = 91/207 (43%), Gaps = 30/207 (14%)
Query: 17 LSCFSFNQDCTSLATGTKAGYKLFS--LSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVV 74
++C ++N + +A+G+ +G + +++ HGSN+ ++ LF SL+
Sbjct: 122 VTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVR-HLKYSLFKKSLLGS 180
Query: 75 VS------------HTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIY 122
VS + + H + IC +S + +L + + L++ I
Sbjct: 181 VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGIC-FSPVNELLFVTIG-------LDKRII 232
Query: 123 IHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKT-VCT 181
+++ KL+KTL+ T L A+ + LA S G+I YD LK+ V T
Sbjct: 233 LYDTSSKKLVKTLVA----DTPLTAVDFMPDGATLAIGSS--RGKIYQYDLRMLKSPVKT 286
Query: 182 IAAHEGTLAAITFNASGSKLASASEKG 208
I+AH+ ++ I F S S+ KG
Sbjct: 287 ISAHKTSVQCIAFQYSTVLTKSSLNKG 313
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 140 ANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGS 199
A +G+C +N L + I+LYD +S K V T+ A + L A+ F G+
Sbjct: 207 APASGICFSPVNE----LLFVTIGLDKRIILYDTSSKKLVKTLVA-DTPLTAVDFMPDGA 261
Query: 200 KLASASEKGTV 210
LA S +G +
Sbjct: 262 TLAIGSSRGKI 272
>gi|206597465 neural precursor cell expressed, developmentally
down-regulated 1 isoform a [Homo sapiens]
Length = 667
Score = 35.8 bits (81), Expect = 0.081
Identities = 50/207 (24%), Positives = 91/207 (43%), Gaps = 30/207 (14%)
Query: 17 LSCFSFNQDCTSLATGTKAGYKLFS--LSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVV 74
++C ++N + +A+G+ +G + +++ HGSN+ ++ LF SL+
Sbjct: 129 VTCVTYNWNDCYIASGSLSGEIILHSVTTNLSSTPFGHGSNQSVR-HLKYSLFKKSLLGS 187
Query: 75 VS------------HTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIY 122
VS + + H + IC +S + +L + + L++ I
Sbjct: 188 VSDNGIVTLWDVNSQSPYHNFDSVHKAPASGIC-FSPVNELLFVTIG-------LDKRII 239
Query: 123 IHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKT-VCT 181
+++ KL+KTL+ T L A+ + LA S G+I YD LK+ V T
Sbjct: 240 LYDTSSKKLVKTLVA----DTPLTAVDFMPDGATLAIGSS--RGKIYQYDLRMLKSPVKT 293
Query: 182 IAAHEGTLAAITFNASGSKLASASEKG 208
I+AH+ ++ I F S S+ KG
Sbjct: 294 ISAHKTSVQCIAFQYSTVLTKSSLNKG 320
Score = 30.8 bits (68), Expect = 2.6
Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 140 ANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGS 199
A +G+C +N L + I+LYD +S K V T+ A + L A+ F G+
Sbjct: 214 APASGICFSPVNE----LLFVTIGLDKRIILYDTSSKKLVKTLVA-DTPLTAVDFMPDGA 268
Query: 200 KLASASEKGTV 210
LA S +G +
Sbjct: 269 TLAIGSSRGKI 279
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 35.0 bits (79), Expect = 0.14
Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 13/175 (7%)
Query: 118 EESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK 177
++++ I ++ K LKTL +N C + S L GS + ++D + K
Sbjct: 108 DKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFN---PQSNLIVSGSFDES-VRIWDVKTGK 162
Query: 178 TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISS 237
+ T+ AH ++A+ FN GS + S+S G + R++ GQ L +S
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG-LCRIWDTASGQCLKTLIDDDN--PPVSF 219
Query: 238 LVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPT 292
+ FS + +++ A++ T+ ++ S+ + T++G+ + + N+ T
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDY-----SKGKCLKTYTGHKNEKYCIFANFSVT 269
Score = 34.3 bits (77), Expect = 0.24
Identities = 24/79 (30%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 181 TIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVF 240
T+A H ++++ F+ +G LAS+S +I+++ DG K + G K + IS + +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSS-ADKLIKIWGAYDG-KFEKTISGHK--LGISDVAW 95
Query: 241 SMDSQFLCASSNTETVHIF 259
S DS L ++S+ +T+ I+
Sbjct: 96 SSDSNLLVSASDDKTLKIW 114
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 35.0 bits (79), Expect = 0.14
Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 13/175 (7%)
Query: 118 EESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK 177
++++ I ++ K LKTL +N C + S L GS + ++D + K
Sbjct: 108 DKTLKIWDVSSGKCLKTLKG-HSNYVFCCNFN---PQSNLIVSGSFDES-VRIWDVKTGK 162
Query: 178 TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISS 237
+ T+ AH ++A+ FN GS + S+S G + R++ GQ L +S
Sbjct: 163 CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDG-LCRIWDTASGQCLKTLIDDDN--PPVSF 219
Query: 238 LVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPT 292
+ FS + +++ A++ T+ ++ S+ + T++G+ + + N+ T
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDY-----SKGKCLKTYTGHKNEKYCIFANFSVT 269
Score = 34.3 bits (77), Expect = 0.24
Identities = 24/79 (30%), Positives = 46/79 (58%), Gaps = 4/79 (5%)
Query: 181 TIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVF 240
T+A H ++++ F+ +G LAS+S +I+++ DG K + G K + IS + +
Sbjct: 40 TLAGHTKAVSSVKFSPNGEWLASSS-ADKLIKIWGAYDG-KFEKTISGHK--LGISDVAW 95
Query: 241 SMDSQFLCASSNTETVHIF 259
S DS L ++S+ +T+ I+
Sbjct: 96 SSDSNLLVSASDDKTLKIW 114
>gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Homo
sapiens]
Length = 928
Score = 34.3 bits (77), Expect = 0.24
Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 21/130 (16%)
Query: 152 HSNSYLA--YPGSLTS------GE---IVLYDGNSLKTVCTIAAHEGTLAAITFNASGSK 200
HSNS + PG +T GE +V D +S V AHE + + FN SG
Sbjct: 306 HSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGML 365
Query: 201 LASASEKGTVIRVFSVPDG---------QKLYEFRRGMKRYVTISSLVFSMDSQFLCASS 251
L + G VF + LY RG + + + FS D +++ S+
Sbjct: 366 LVTTDTLGHDFHVFQILTHPWSSSQCAVHHLYTLHRG-ETEAKVQDICFSHDCRWVVVST 424
Query: 252 NTETVHIFKL 261
T H+F +
Sbjct: 425 LRGTSHVFPI 434
>gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Homo
sapiens]
Length = 913
Score = 34.3 bits (77), Expect = 0.24
Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 21/130 (16%)
Query: 152 HSNSYLA--YPGSLTS------GE---IVLYDGNSLKTVCTIAAHEGTLAAITFNASGSK 200
HSNS + PG +T GE +V D +S V AHE + + FN SG
Sbjct: 306 HSNSRRSPLVPGIITVIDTETVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGML 365
Query: 201 LASASEKGTVIRVFSVPDG---------QKLYEFRRGMKRYVTISSLVFSMDSQFLCASS 251
L + G VF + LY RG + + + FS D +++ S+
Sbjct: 366 LVTTDTLGHDFHVFQILTHPWSSSQCAVHHLYTLHRG-ETEAKVQDICFSHDCRWVVVST 424
Query: 252 NTETVHIFKL 261
T H+F +
Sbjct: 425 LRGTSHVFPI 434
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 34.3 bits (77), Expect = 0.24
Identities = 38/175 (21%), Positives = 80/175 (45%), Gaps = 13/175 (7%)
Query: 118 EESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK 177
++++ + +++ K LKTL +N C + S L GS + +++ + K
Sbjct: 104 DKTLKLWDVRSGKCLKTLKG-HSNYVFCCNFN---PPSNLIISGSFDE-TVKIWEVKTGK 158
Query: 178 TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISS 237
+ T++AH ++A+ FN SGS + S S G + R++ GQ L +S
Sbjct: 159 CLKTLSAHSDPVSAVHFNCSGSLIVSGSYDG-LCRIWDAASGQCLKTLVDDDN--PPVSF 215
Query: 238 LVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPT 292
+ FS + +++ ++ T+ ++ SR T++G+ + + N+ T
Sbjct: 216 VKFSPNGKYILTATLDNTLKLWDY-----SRGRCLKTYTGHKNEKYCIFANFSVT 265
Score = 33.1 bits (74), Expect = 0.52
Identities = 22/80 (27%), Positives = 45/80 (56%), Gaps = 4/80 (5%)
Query: 180 CTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLV 239
CT+ H ++++ F+ +G LAS+S +I ++ DG+ YE + + IS +
Sbjct: 35 CTLVGHTEAVSSVKFSPNGEWLASSSADRLII-IWGAYDGK--YE-KTLYGHNLEISDVA 90
Query: 240 FSMDSQFLCASSNTETVHIF 259
+S DS L ++S+ +T+ ++
Sbjct: 91 WSSDSSRLVSASDDKTLKLW 110
>gi|75709220 cleavage stimulation factor subunit 1 [Homo sapiens]
Length = 431
Score = 33.9 bits (76), Expect = 0.31
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 149 SINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTI-AAHEGTLAAITFNASGSKLASASEK 207
S+N+++S Y G I L+DG S + + T AH+G + SK +S K
Sbjct: 267 SVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGK 326
Query: 208 GTVIRVFSVPDGQKLYEF 225
+V +++ + G+ L +
Sbjct: 327 DSVAKLWEISTGRTLVRY 344
>gi|4557491 cleavage stimulation factor subunit 1 [Homo sapiens]
Length = 431
Score = 33.9 bits (76), Expect = 0.31
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 149 SINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTI-AAHEGTLAAITFNASGSKLASASEK 207
S+N+++S Y G I L+DG S + + T AH+G + SK +S K
Sbjct: 267 SVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGK 326
Query: 208 GTVIRVFSVPDGQKLYEF 225
+V +++ + G+ L +
Sbjct: 327 DSVAKLWEISTGRTLVRY 344
>gi|75709217 cleavage stimulation factor subunit 1 [Homo sapiens]
Length = 431
Score = 33.9 bits (76), Expect = 0.31
Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Query: 149 SINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTI-AAHEGTLAAITFNASGSKLASASEK 207
S+N+++S Y G I L+DG S + + T AH+G + SK +S K
Sbjct: 267 SVNYNSSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGK 326
Query: 208 GTVIRVFSVPDGQKLYEF 225
+V +++ + G+ L +
Sbjct: 327 DSVAKLWEISTGRTLVRY 344
>gi|157266266 WD repeat domain 86 [Homo sapiens]
Length = 376
Score = 33.9 bits (76), Expect = 0.31
Identities = 26/81 (32%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 173 GNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRY 232
G S VC A H G + ++ + G +L + SE GT R++S DGQ +G + Y
Sbjct: 4 GGSALRVC--ADHRGGINWLSLSPDGQRLLTGSEDGTA-RLWSTADGQ-CCALLQGHESY 59
Query: 233 VTISSLVFSMDSQFLCASSNT 253
VT L ++ F C++ T
Sbjct: 60 VTFCQL--EDEAAFTCSADCT 78
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,105,304
Number of Sequences: 37866
Number of extensions: 739706
Number of successful extensions: 2059
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 1988
Number of HSP's gapped (non-prelim): 93
length of query: 446
length of database: 18,247,518
effective HSP length: 105
effective length of query: 341
effective length of database: 14,271,588
effective search space: 4866611508
effective search space used: 4866611508
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.