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Search of human proteins with 110556640
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110556640 DNA helicase HEL308 [Homo sapiens]
(1101 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110556640 DNA helicase HEL308 [Homo sapiens] 2183 0.0
gi|139394648 DNA polymerase theta [Homo sapiens] 416 e-116
gi|40217847 activating signal cointegrator 1 complex subunit 3-l... 130 5e-30
gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD prote... 129 2e-29
gi|130484567 HFM1 protein [Homo sapiens] 115 3e-25
gi|76880486 activating signal cointegrator 1 complex subunit 3 i... 114 7e-25
gi|193211480 superkiller viralicidic activity 2-like 2 [Homo sap... 87 1e-16
gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sap... 66 2e-10
gi|67782311 superkiller viralicidic activity 2-like homolog [Hom... 65 5e-10
gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Hom... 62 3e-09
gi|14591902 RecQ protein-like [Homo sapiens] 50 9e-06
gi|14591904 RecQ protein-like [Homo sapiens] 50 9e-06
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 39 0.035
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 39 0.035
gi|116812616 RecQ protein-like 4 [Homo sapiens] 37 0.10
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ... 36 0.18
gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens] 35 0.39
gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens] 35 0.39
gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens] 35 0.39
gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens] 35 0.51
gi|117500790 FERM domain containing 3 [Homo sapiens] 34 0.67
gi|122937345 myosin VB [Homo sapiens] 34 0.87
gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo... 33 1.1
gi|118600971 transcription elongation factor A (SII)-like 6 [Hom... 33 1.5
gi|239747122 PREDICTED: hypothetical protein XP_002343916 [Homo ... 33 1.9
gi|239746558 PREDICTED: hypothetical protein XP_002343788 [Homo ... 33 1.9
gi|16445033 ACRC protein [Homo sapiens] 33 1.9
gi|55956801 SWI/SNF related, matrix associated, actin dependent ... 32 4.3
gi|55749431 transcription elongation factor A (SII)-like 3 [Homo... 32 4.3
gi|14249718 transcription elongation factor A (SII)-like 3 [Homo... 32 4.3
>gi|110556640 DNA helicase HEL308 [Homo sapiens]
Length = 1101
Score = 2183 bits (5656), Expect = 0.0
Identities = 1101/1101 (100%), Positives = 1101/1101 (100%)
Query: 1 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP 60
MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP
Sbjct: 1 MDECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLP 60
Query: 61 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI 120
VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI
Sbjct: 61 VEVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFI 120
Query: 121 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY 180
AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY
Sbjct: 121 AQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTENQSGY 180
Query: 181 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI 240
EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI
Sbjct: 181 EGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCI 240
Query: 241 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN 300
EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN
Sbjct: 241 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEIN 300
Query: 301 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP 360
VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP
Sbjct: 301 VAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLP 360
Query: 361 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG 420
TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG
Sbjct: 361 TSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKG 420
Query: 421 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT 480
RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT
Sbjct: 421 RFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMT 480
Query: 481 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK 540
LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK
Sbjct: 481 LAKILYTSKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSK 540
Query: 541 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF 600
AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF
Sbjct: 541 AENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF 600
Query: 601 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS 660
LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS
Sbjct: 601 LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYS 660
Query: 661 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI 720
TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI
Sbjct: 661 TGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESI 720
Query: 721 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT 780
LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT
Sbjct: 721 LILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGT 780
Query: 781 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG 840
FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG
Sbjct: 781 FFGVQQKVLLKEKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGRASFKG 840
Query: 841 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE 900
TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE
Sbjct: 841 TIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPYDLVSQCNPDWMIYFRQFSQLSPAE 900
Query: 901 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP 960
QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP
Sbjct: 901 QNVAAILGVSESFIGKKASGQAIGKKVDKNVVNRLYLSFVLYTLLKETNIWTVSEKFNMP 960
Query: 961 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL 1020
RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL
Sbjct: 961 RGYIQNLLTGTASFSSCVLHFCEELEEFWVYRALLVELTKKLTYCVKAELIPLMEVTGVL 1020
Query: 1021 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV 1080
EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV
Sbjct: 1021 EGRAKQLYSAGYKSLMHLANANPEVLVRTIDHLSRRQAKQIVSSAKMLLHEKAEALQEEV 1080
Query: 1081 EELLRLPSDFPGAVASSTDKA 1101
EELLRLPSDFPGAVASSTDKA
Sbjct: 1081 EELLRLPSDFPGAVASSTDKA 1101
>gi|139394648 DNA polymerase theta [Homo sapiens]
Length = 2590
Score = 416 bits (1070), Expect = e-116
Identities = 277/801 (34%), Positives = 438/801 (54%), Gaps = 63/801 (7%)
Query: 317 YSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQE 376
+ LP V + Y F G++K++EWQ CL L V E KNL+YS PTS GKTLVAE+L+L+
Sbjct: 74 WGLPKAVLEKYHSF-GVKKMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKR 132
Query: 377 LLCCRKDVLMILPYVAIVQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIA 436
+L RK L ILP+V++ +EK L S E+G V+ Y GS P++ + +
Sbjct: 133 VLEMRKKALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTS---PSRHFSSLDIAVC 189
Query: 437 TIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYT--------- 487
TIE+ + L+N LIE ++D LG+VVVDELHM+G+ RG LE+ L KI Y
Sbjct: 190 TIERANGLINRLIEENKMDLLGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQA 249
Query: 488 ------SKTTQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKA 541
S QI+GMSATL N+E + +L AE Y + FRPV L E +K+ ++IY DS
Sbjct: 250 DLASSLSNAVQIVGMSATLPNLELVASWLNAELYHTDFRPVPLLESVKVGNSIY--DSSM 307
Query: 542 ENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVI-PNYSCLVFCPSKKNCENVAEMICK- 599
+ F +L K D DH+V+L E I N+S L+FCPSKK CE +A++I +
Sbjct: 308 KLVREFEPMLQVKG-------DEDHVVSLCYETICDNHSVLLFCPSKKWCEKLADIIARE 360
Query: 600 FLSKEYLKH-------------KEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSG 646
F + + ++KE EV+ L+ + +G L VL++T+P+GVA+HH+G
Sbjct: 361 FYNLHHQAEGLVKPSECPPVILEQKELLEVMDQLRRLPSG-LDSVLQKTVPWGVAFHHAG 419
Query: 647 LTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIG 706
LT +ER ++E A+ G++ + TSTL++GVNLPARRVI+R P L YKQM+G
Sbjct: 420 LTFEERDIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVG 479
Query: 707 RAGRAGIDTIGESILILQEKDKQQVLELI---TKPLENCYSHLV-QEFTKGIQTLFLSLI 762
RAGR G+DT+GESILI + +K + + L+ KP+ +C +E T + L +I
Sbjct: 480 RAGRKGVDTVGESILICKNSEKSKGIALLQGSLKPVRSCLQRREGEEVTGSMIRAILEII 539
Query: 763 GLKIATNLDDIYHFMNGTFFGVQQK-----VLLKEKSLWEITVES-LRYLTEKGLLQKDT 816
+A+ D++ + TF K + ++S+ +E+ + +L E +Q
Sbjct: 540 VGGVASTSQDMHTYAACTFLAASMKEGKQGIQRNQESVQLGAIEACVMWLLENEFIQSTE 599
Query: 817 IYKSEEEVQYNFHITKLGRASFKGTIDLAYCDILYRDLKKGLEGLVLESLLHLIYLTTPY 876
E Y H T LG A+ ++ A ++ DL++ ++G VLE+ LH++YL TP
Sbjct: 600 ASDGTEGKVY--HPTHLGSATLSSSLSPADTLDIFADLQRAMKGFVLENDLHILYLVTPM 657
Query: 877 DLVSQCNPDWMIYFRQFSQLSPAEQNVAAILGVSESFIGKKASGQAIGKKVDKN----VV 932
DW +F + +L + + VA ++GV E F+ + G+ + + ++ +
Sbjct: 658 -FEDWTTIDWYRFFCLWEKLPTSMKRVAELVGVEEGFLARCVKGKVVARTERQHRQMAIH 716
Query: 933 NRLYLSFVLYTLLKETNIWTVSEKFNMPRGYIQNLLTGTASFSSCVLHFCEELEEFWVYR 992
R + S VL L+ E + +++K+ RG IQ+L A ++ + F L +
Sbjct: 717 KRFFTSLVLLDLISEVPLREINQKYGCNRGQIQSLQQSAAVYAGMITVFSNRL-GWHNME 775
Query: 993 ALLVELTKKLTYCVKAELIPLMEVTGVLEGRAKQLYSAGYKSLMHLANAN-PEVLVRTID 1051
LL + K+LT+ ++ EL L+ V+ + RA+ LY++G+ ++ LA AN EV V +
Sbjct: 776 LLLSQFQKRLTFGIQRELCDLVRVSLLNAQRARVLYASGFHTVADLARANIVEVEVILKN 835
Query: 1052 HLSRRQAKQIVSSAKMLLHEK 1072
+ + A++ V + + E+
Sbjct: 836 AVPFKSARKAVDEEEEAVEER 856
>gi|40217847 activating signal cointegrator 1 complex subunit 3-like
1 [Homo sapiens]
Length = 2136
Score = 130 bits (328), Expect = 5e-30
Identities = 150/606 (24%), Positives = 264/606 (43%), Gaps = 90/606 (14%)
Query: 276 NAKAQTPIFSRSKQLKDTLLSEEINVA--KKTVESSSNDLGPFYSLPSKVRDLYAQFKGI 333
N + Q P S +Q K EE++V K S L P LP + + FK +
Sbjct: 425 NKRCQLPDGSFRRQRKGY---EEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTL 481
Query: 334 EKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQEL-LCCRKD--------- 383
++ + L +++ +NL+ PT GKT VA + ML+E+ D
Sbjct: 482 NRI----QSKLYRAALETDENLLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFK 537
Query: 384 VLMILPYVAIVQEKISG----LSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIE 439
++ I P ++VQE + L+++GI + ++ K T+ + + T E
Sbjct: 538 IIYIAPMRSLVQEMVGSFGKRLATYGITVAELTGDHQLCKEEISATQ------IIVCTPE 591
Query: 440 KGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQ----IIG 495
K + E + L+++DE+H++ + RG LE +A+ + + TQ +IG
Sbjct: 592 KWDIITRKGGERTYTQLVRLIILDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIG 650
Query: 496 MSATLNNVEDLQKFLQAE------YYTSQFRPVELKE-YLKINDTIYEVDSKAENGMTFS 548
+SATL N ED+ FL+ + Y+ + FRPV L++ Y+ I + + N + +
Sbjct: 651 LSATLPNYEDVATFLRVDPAKGLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYE 710
Query: 549 RLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKF-LSKEYLK 607
+++ + + + LVF S+K A I L K+ L
Sbjct: 711 KIMEHAGKNQV---------------------LVFVHSRKETGKTARAIRDMCLEKDTLG 749
Query: 608 HKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLF 667
+E + L+ LK +P+G A HH+G+T +R L+E+ ++ + +
Sbjct: 750 LFLREGSASTEVLRTEAEQCKNLELKDLLPYGFAIHHAGMTRVDRTLVEDLFADKHIQVL 809
Query: 668 TCTSTLAAGVNLPARRVILRAPYVAK------EFLKRNQYKQMIGRAGRAGIDTIGESIL 721
T+TLA GVNLPA VI++ V L QM+GRAGR DT GE IL
Sbjct: 810 VSTATLAWGVNLPAHTVIIKGTQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGIL 869
Query: 722 ILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTF 781
I + Q L L+ + L + + + + + I L N D +++ +
Sbjct: 870 ITSHGELQYYLSLLNQQLP-----IESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAY 924
Query: 782 FGVQQKVLLKEKSLWEITVESLR------------YLTEKGLLQKDTIYKSEEEVQYNFH 829
++ +L+ +L+ I+ + L+ T +L K+ + K +++ NF
Sbjct: 925 LYIR---MLRSPTLYGISHDDLKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTG-NFQ 980
Query: 830 ITKLGR 835
+T+LGR
Sbjct: 981 VTELGR 986
Score = 90.9 bits (224), Expect = 6e-18
Identities = 110/453 (24%), Positives = 189/453 (41%), Gaps = 63/453 (13%)
Query: 354 NLIYSLPTSGGKTLVAEILMLQELLCCRKD-VLMILPYVAIVQEK-ISGLSSFGIELGFF 411
N+ PT GKT+ AE +L+ LL + + I P A+ ++ + F L
Sbjct: 1345 NVFVGAPTGSGKTICAEFAILRMLLQSSEGRCVYITPMEALAEQVYMDWYEKFQDRLNKK 1404
Query: 412 VEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEG 471
V G K K ++ I+T EK L + + ++ L VVDE+H+IG G
Sbjct: 1405 VVLLTGETST--DLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-G 1461
Query: 472 SRGATLEMTLAKILYTS----KTTQIIGMSATLNNVEDLQKFLQAEYYTSQF------RP 521
G LE+ +++ Y S + +I+ +S++L+N +D+ +L TS F RP
Sbjct: 1462 ENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSA-TSTFNFHPNVRP 1520
Query: 522 VELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCL 581
V L+ +++ N ++ T + +T+ P +
Sbjct: 1521 VPLELHIQG--------------------FNISHTQTRLLSMAKPVYHAITKHSPKKPVI 1560
Query: 582 VFCPSKKNCENVAEMICKFLSKE-----YLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTI 636
VF PS+K A I + + +L EK+ ++ L + LK T+
Sbjct: 1561 VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSD-------STLKETL 1613
Query: 637 PFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILR-APYVAKEF 695
GV Y H GL+ ER+L+E+ +S+G + + + +L G+N+ A VI+ Y +
Sbjct: 1614 LNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTQYYNGKI 1673
Query: 696 LKRNQYK-----QMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPL--ENCYSHLVQ 748
Y QM+G A R D G +++ Q K + + +PL E+ H +
Sbjct: 1674 HAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMH 1733
Query: 749 EFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTF 781
+ F + I K N D ++ TF
Sbjct: 1734 DH-------FNAEIVTKTIENKQDAVDYLTWTF 1759
>gi|169218225 PREDICTED: similar to U5 snRNP-specific 200kD protein,
partial [Homo sapiens]
Length = 1700
Score = 129 bits (323), Expect = 2e-29
Identities = 145/585 (24%), Positives = 255/585 (43%), Gaps = 87/585 (14%)
Query: 297 EEINVA--KKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKN 354
EE++V K S L P LP + + FK + ++ + L +++ +N
Sbjct: 7 EEVHVPALKPKPFGSEEQLLPVEKLPKYAQAGFEGFKTLNRI----QSKLYRAALETDEN 62
Query: 355 LIYSLPTSGGKTLVAEILMLQEL-LCCRKD---------VLMILPYVAIVQEKISG---- 400
L+ PT GKT VA + ML+E+ D ++ I P ++VQE +
Sbjct: 63 LLLCAPTGAGKTNVALMCMLREIGKHINMDGTINVDDFKIIYIAPMRSLVQEMVGSFGKR 122
Query: 401 LSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLV 460
L+++GI + ++ K T+ + + T EK + E + L+
Sbjct: 123 LATYGITVAELTGDHQLCKEEISATQ------IIVCTPEKWDIITRKGGERTYTQLVRLI 176
Query: 461 VVDELHMIGEGSRGATLEMTLAKILYTSKTTQ----IIGMSATLNNVEDLQKFLQAE--- 513
V+DE+H++ + RG LE +A+ + + TQ +IG+SATL N ED+ FL+ +
Sbjct: 177 VLDEIHLLHD-DRGPVLEALVARAIRNIEMTQEDVRLIGLSATLPNYEDVATFLRVDPAK 235
Query: 514 ---YYTSQFRPVELKE-YLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKMDPDHLVA 569
Y+ + FRPV L++ Y+ I + + N + + +++ + + +
Sbjct: 236 GLFYFDNSFRPVPLEQTYVGITEKKAIKRFQIMNEIVYEKIMEHAGKNQV---------- 285
Query: 570 LVTEVIPNYSCLVFCPSKKNCENVAEMICKF-LSKEYLKHKEKEKCEVIKNLKNIGNGNL 628
LVF S+K A I L K+ L +E + L+
Sbjct: 286 -----------LVFVHSRKETGKTARAIRDMCLEKDTLGLFLREGSASTEVLRTEAEQCK 334
Query: 629 CPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRA 688
LK +P+G A HH+G+T +R L+E+ + + + T+TLA GVNLPA VI++
Sbjct: 335 NLELKDLLPYGFAIHHAGMTRVDRTLVEDLFGDKHIQVLVSTATLAWGVNLPAHTVIIKG 394
Query: 689 PYVAK------EFLKRNQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPLENC 742
V L QM+GRAGR DT GE ILI + Q L L+ + L
Sbjct: 395 TQVYSPEKGRWTELGALDILQMLGRAGRPQYDTKGEGILITSHGELQYYLSLLNQQLP-- 452
Query: 743 YSHLVQEFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTFFGVQQKVLLKEKSLWEITVES 802
+ + + + + I L N D +++ + ++ +L+ +L+ I+ +
Sbjct: 453 ---IESQMVSKLPDMLNAEIVLGNVQNAKDAVNWLGYAYLYIR---MLRSPTLYGISHDD 506
Query: 803 LR------------YLTEKGLLQKDTIYKSEEEVQYNFHITKLGR 835
L+ T +L K+ + K +++ NF +T+LGR
Sbjct: 507 LKGDPLLDQRRLDLVHTAALMLDKNNLVKYDKKTG-NFQVTELGR 550
Score = 90.5 bits (223), Expect = 8e-18
Identities = 109/453 (24%), Positives = 189/453 (41%), Gaps = 63/453 (13%)
Query: 354 NLIYSLPTSGGKTLVAEILMLQELLCCRKDVLMILPYVAIVQEKI--SGLSSFGIELGFF 411
N+ PT GKT+ AE +L+ LL + + + + + QE++ F L
Sbjct: 909 NVFVGAPTGSGKTICAEFAILRMLLQNSEGRCVYITPMRLWQEQVYMDWYEKFQDRLNKK 968
Query: 412 VEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEG 471
V G K K ++ I+T EK L + + ++ L VVDE+H+IG G
Sbjct: 969 VVLLTGETST--DLKLLGKGNIIISTPEKWDILSRRWKQRKNVQNINLFVVDEVHLIG-G 1025
Query: 472 SRGATLEMTLAKILYTS----KTTQIIGMSATLNNVEDLQKFLQAEYYTSQF------RP 521
G LE+ +++ Y S + +I+ +S++L+N +D+ +L TS F RP
Sbjct: 1026 ENGPVLEVICSRMRYISSQIERPIRIVALSSSLSNAKDVAHWLGCSA-TSTFNFHPNVRP 1084
Query: 522 VELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCL 581
V L+ +++ N ++ T + +T+ P +
Sbjct: 1085 VPLELHIQG--------------------FNISHTQTRLLSMAKPVFHAITKHSPKKPVI 1124
Query: 582 VFCPSKKNCENVAEMICKFLSKE-----YLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTI 636
VF PS+K A I + + +L EK+ ++ L + LK T+
Sbjct: 1125 VFVPSRKQTRLTAIDILTTCAADIQRQRFLHCTEKDLIPYLEKLSD-------STLKETL 1177
Query: 637 PFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILR-APYVAKEF 695
GV Y H GL+ ER+L+E+ +S+G + + + +L G+N+ A VI+ Y +
Sbjct: 1178 LNGVGYLHEGLSPMERRLVEQLFSSGAIQVVVASRSLCWGMNVAAHLVIIMDTLYYNGKI 1237
Query: 696 LKRNQYK-----QMIGRAGRAGIDTIGESILILQEKDKQQVLELITKPL--ENCYSHLVQ 748
Y QM+G A R D G +++ Q K + + +PL E+ H +
Sbjct: 1238 HAYVDYPIYDVLQMVGHANRPLQDDEGRCVIMCQGSKKDFFKKFLYEPLPVESHLDHCMH 1297
Query: 749 EFTKGIQTLFLSLIGLKIATNLDDIYHFMNGTF 781
+ F + I K N D ++ TF
Sbjct: 1298 DH-------FNAEIVTKTIENKQDAVDYLTWTF 1323
>gi|130484567 HFM1 protein [Homo sapiens]
Length = 1435
Score = 115 bits (287), Expect = 3e-25
Identities = 150/654 (22%), Positives = 266/654 (40%), Gaps = 94/654 (14%)
Query: 226 SSHNTVNEELPHNCIEQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMT----GNAKAQT 281
S+ N ++ + I Q + N S S + + NA + G +
Sbjct: 179 SNDNELDSHIGSVKIVQTEMNKGKSRNYSNSKQKFQYSANVFTANNAFSASEIGEGMFKA 238
Query: 282 PIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYEWQH 341
P FS + Q D ++ E+ L +P+K R ++ +F +
Sbjct: 239 PSFSVAFQPHDI---------QEVTENGLGSLKAVTEIPAKFRSIFKEFPYFNYIQSKAF 289
Query: 342 TCLTLNSVQERKNLIYSLPTSGGKTLVAEI-----LMLQELLCCRKDVLMILPYVAIVQE 396
L +N + PT GKT+V E+ LM L ++ + P A+ +
Sbjct: 290 DDLLYTD----RNFVICAPTGSGKTVVFELAITRLLMEVPLPWLNIKIVYMAPIKALCSQ 345
Query: 397 KISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDS 456
+ +G +E G + + + T EK S+ + +
Sbjct: 346 RFDDWKEKFGPIGLNCKELTGDTV-MDDLFEIQHAHIIMTTPEKWDSMTRKWRDNSLVQL 404
Query: 457 LGLVVVDELHMIGEGSRGATLEM------TLAKILYTSKTT------QIIGMSATLNNVE 504
+ L ++DE+H++ + +RG TLE+ T+ + T K T + + +SAT+ N E
Sbjct: 405 VRLFLIDEVHIVKDENRGPTLEVVVSRMKTVQSVSQTLKNTSTAIPMRFVAVSATIPNAE 464
Query: 505 DLQKFLQ-------AEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYKYSD 557
D+ ++L RPV+L++ + + S + F LNYK
Sbjct: 465 DIAEWLSDGERPAVCLKMDESHRPVKLQKVV-----LGFPCSSNQTEFKFDLTLNYK--- 516
Query: 558 TLKKMDPDHLVALVTEVIPNYS----CLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEK 613
+ VI YS LVFC ++K + A ++ K +K + ++K++
Sbjct: 517 -------------IASVIQMYSDQKPTLVFCATRKGVQQAASVLVKD-AKFIMTVEQKQR 562
Query: 614 CEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTL 673
+ K ++ + L +LK G AYHH+G+ +RK++E A++ G L + TSTL
Sbjct: 563 LQ--KYAYSVRDSKLRDILKD----GAAYHHAGMELSDRKVVEGAFTVGDLPVLFTTSTL 616
Query: 674 AAGVNLPARRVILRAP--YVAKEF--LKRNQYKQMIGRAGRAGIDTIGESILI--LQEKD 727
A GVNLPA V++++ Y F QMIGRAGR DT ++++ L +D
Sbjct: 617 AMGVNLPAHLVVIKSTMHYAGGLFEEYSETDILQMIGRAGRPQFDTTATAVIMTRLSTRD 676
Query: 728 KQ-QVLELITKPLENCYSHLVQEFTKGIQTLFLSLIGLK---IATNLDDIYHFMNGTFFG 783
K Q+L + + HL++ I ++ + + I + L I N + +G
Sbjct: 677 KYIQMLACRDTVESSLHRHLIEHLNAEIVLHTITDVNIAVEWIRSTLLYIRALKNPSHYG 736
Query: 784 VQQKVLLK--EKSLWEITVESLRYLTEKGLLQKDTIYKSEEEVQYNFHITKLGR 835
+ E L E+ +++L L+ L++ D NF T+ GR
Sbjct: 737 FASGLNKDGIEAKLQELCLKNLNDLSSLDLIKMDE--------GVNFKPTEAGR 782
>gi|76880486 activating signal cointegrator 1 complex subunit 3
isoform a [Homo sapiens]
Length = 2202
Score = 114 bits (284), Expect = 7e-25
Identities = 139/572 (24%), Positives = 240/572 (41%), Gaps = 89/572 (15%)
Query: 316 FYSLPSKVRDL----YAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEI 371
F P ++DL FKG+++L Q + +N++ PT GKT +A +
Sbjct: 453 FEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFE-TAYNTNENMLICAPTGAGKTNIAML 511
Query: 372 LMLQELL------CCRKD---VLMILPYVAIVQEKISGLSSFGIELGFFVEEYAG----S 418
+L E+ +K+ ++ + P A+ E S LG V+E G S
Sbjct: 512 TVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLS 571
Query: 419 KGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGRIDSL-GLVVVDELHMIGEGSRGATL 477
K T+ + + T EK + + + + L+++DE+H++ E RG L
Sbjct: 572 KSEILRTQ------MLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHE-DRGPVL 624
Query: 478 EMTLAKILYTSKTTQ----IIGMSATLNNVEDLQKFLQAE------YYTSQFRPVELKEY 527
E +A+ L ++TQ I+G+SATL N D+ FL ++ +FRPV L +
Sbjct: 625 ESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQT 684
Query: 528 LKINDTIYEVDSKAENGMT-FSRLLNYKYSDTLKKMDPDHLVALVTEV--IPNYSCLVFC 584
+ K N M + + Y + LK++ H V + + +
Sbjct: 685 F--------LGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNATVRTAMSLI 736
Query: 585 PSKKNCENVAEMICKFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHH 644
KNC ++ L K+ ++ +N + ++ P G + HH
Sbjct: 737 ERAKNCGHIPFFFPTQGHDYVLAEKQVQRS---RNKQ----------VRELFPDGFSIHH 783
Query: 645 SGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAP--YVAKE----FLKR 698
+G+ +R L+E +S G + + CT+TLA GVNLPA VI++ Y AK L
Sbjct: 784 AGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGI 843
Query: 699 NQYKQMIGRAGRAGIDTIGESILILQEKDKQQVLELITK--PLENCYSHLVQEFTKGIQT 756
Q+ GRAGR D GE I+I L L+T+ P+E+ +F + +
Sbjct: 844 LDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIES-------QFLESLAD 896
Query: 757 LFLSLIGLKIATNLDDIYHFMNGTF-----------FGVQQKVLLKEKSLWEITVESLRY 805
+ I L TN+++ +++ T+ +G+ K + +L + + +
Sbjct: 897 NLNAEIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIE 956
Query: 806 LTEKGLLQKDTIYKSEEEVQYNFHITKLGRAS 837
+ K L K + + EE Y F T LGR +
Sbjct: 957 VGRK--LDKAQMIRFEERTGY-FSSTDLGRTA 985
Score = 113 bits (283), Expect = 9e-25
Identities = 127/520 (24%), Positives = 221/520 (42%), Gaps = 68/520 (13%)
Query: 331 KGIEKLYEWQHTCLTLNSVQERK---------NLIYSLPTSGGKTLVAEILMLQEL-LCC 380
K E LY + H N VQ + N++ PT GKT+ AE+ + +
Sbjct: 1316 KAYEALYNFSH----FNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYP 1371
Query: 381 RKDVLMILPYVAIVQEKISGLS-SFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIE 439
+ I P A+V+E++ +LG V E G P K K L + T E
Sbjct: 1372 TSKAVYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVT--PDMKSIAKADLIVTTPE 1429
Query: 440 KGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILY----TSKTTQIIG 495
K + S + + ++++DE+H++GE RG LE+ +++ + T K +I+G
Sbjct: 1430 KWDGVSRSWQNRNYVQQVTILIIDEIHLLGE-ERGPVLEVIVSRTNFISSHTEKPVRIVG 1488
Query: 496 MSATLNNVEDLQKFLQAEYY-TSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRLLNYK 554
+S L N DL +L + FRP + EV + G
Sbjct: 1489 LSTALANARDLADWLNIKQMGLFNFRP-------SVRPVPLEVHIQGFPGQ--------H 1533
Query: 555 YSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLS-----KEYLKHK 609
Y + M+ A+ + P L+F S++ A + FL+ K++L
Sbjct: 1534 YCPRMASMNKPAFQAIRSHS-PAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMD 1592
Query: 610 EKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTC 669
E+E +I +++ LK T+ FG+ HH+GL +RK +EE + + +
Sbjct: 1593 EREMENIIATVRDSN-------LKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIA 1645
Query: 670 TSTLAAGVNLPARRVILRAPYVAKEFLKR------NQYKQMIGRAGRAGIDTIGESILIL 723
TSTLA GVN PA VI++ +R QM+GRAGR D G++++++
Sbjct: 1646 TSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILV 1705
Query: 724 QEKDKQQVLELITKPLENCYSHLVQEFTKGIQTLFLSL-IGLKIATNLDDIYHFMNGTFF 782
+ K + + +P V+ G+ + L+ I T+ D ++ T+F
Sbjct: 1706 HDIKKDFYKKFLYEPFP------VESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYF 1759
Query: 783 GVQQKVLLKEKSLWEITVES----LRYLTEKGLLQKDTIY 818
+ + +L +++ +S L +L EK L++ + Y
Sbjct: 1760 FRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSY 1799
>gi|193211480 superkiller viralicidic activity 2-like 2 [Homo
sapiens]
Length = 1042
Score = 86.7 bits (213), Expect = 1e-16
Identities = 127/575 (22%), Positives = 241/575 (41%), Gaps = 107/575 (18%)
Query: 241 EQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTGNAK---------AQTPIFSRSKQLK 291
++ ++ D+ K S K L++ T N K PIF + +++
Sbjct: 24 KKDKEKDKGKWKGPPGSADKAGKRFDGKLQSESTNNGKNKRDVDFEGTDEPIFGKKPRIE 83
Query: 292 DTLLSEEINVAK----------KTVESSSNDLG-----PFYSLPSKVRDLYAQFKGIEKL 336
+++ +E++++A +TVE ++++ + L +V ++ I
Sbjct: 84 ESI-TEDLSLADLMPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPFILDA 142
Query: 337 YEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEI---LMLQELLCCRKDVLMILPYVAI 393
++ + + V ++++ S TS GKT+ AE L L+E ++ V+ P A+
Sbjct: 143 FQRE----AIQCVDNNQSVLVSAHTSAGKTVCAEYAIALALRE----KQRVIFTSPIKAL 194
Query: 394 VQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGR 453
+K + ++G + PT S + T E S++ E R
Sbjct: 195 SNQKYREMYEEFQDVGLMTGDVT-----INPTA-----SCLVMTTEILRSMLYRGSEVMR 244
Query: 454 IDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFL--- 510
+ V+ DE+H + + RG E T I+ + +SAT+ N +++
Sbjct: 245 --EVAWVIFDEIHYMRDSERGVVWEET---IILLPDNVHYVFLSATIPNARQFAEWICHL 299
Query: 511 ---QAEYYTSQFRPVELKEYL--KINDTIYEV-----DSKAENGMTFSRLLNYKYSDTLK 560
+ +RP L+ Y+ D ++ V D + +N T ++L + + L
Sbjct: 300 HKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVL--RDAGDLA 357
Query: 561 KMD----------PDHLVALVTEVIPN--YSCLVFCPSKKNCENVAEMICKFLSKEYLKH 608
K D P ++ +V ++ ++F SKK+CE A + K ++
Sbjct: 358 KGDQKGRKGGTKGPSNVFKIVKMIMERNFQPVIIFSFSKKDCEAYALQMTKL---DFNTD 414
Query: 609 KEKEKCEVI------------KNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLE 656
+EK+ E + K L + + + P+LKR G+ HH GL ++ +E
Sbjct: 415 EEKKMVEEVFSNAIDCLSDEDKKLPQVEH--VLPLLKR----GIGIHHGGLLPILKETIE 468
Query: 657 EAYSTGVLCLFTCTSTLAAGVNLPARRVIL--RAPYVAKEF--LKRNQYKQMIGRAGRAG 712
+S G++ T T A G+N+PAR V+ + K+F + +Y QM GRAGR G
Sbjct: 469 ILFSEGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRG 528
Query: 713 IDTIGESILILQEKDK----QQVLELITKPLENCY 743
+D G IL++ EK +Q+L+ PL + +
Sbjct: 529 MDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSAF 563
>gi|222831595 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 [Homo sapiens]
Length = 1712
Score = 65.9 bits (159), Expect = 2e-10
Identities = 35/87 (40%), Positives = 50/87 (57%), Gaps = 3/87 (3%)
Query: 632 LKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYV 691
LK G+ YHHS ++ E++L+E + G L + T T TLA GVN+P + V+ V
Sbjct: 1253 LKALAERGIGYHHSAMSFKEKQLVEILFRKGYLRVVTATGTLALGVNMPCKSVVFAQNSV 1312
Query: 692 AKEFLKRNQYKQMIGRAGRAGIDTIGE 718
+L Y+QM GRAGR G D +G+
Sbjct: 1313 ---YLDALNYRQMSGRAGRRGQDLMGD 1336
>gi|67782311 superkiller viralicidic activity 2-like homolog [Homo
sapiens]
Length = 1246
Score = 64.7 bits (156), Expect = 5e-10
Identities = 113/496 (22%), Positives = 198/496 (39%), Gaps = 87/496 (17%)
Query: 285 SRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLP----SKVRDLYAQFKGIEKLYEWQ 340
+R+ L+D +L +E + A T E+ +++P S V D Y + ++W
Sbjct: 252 ARASSLEDLVL-KEASTAVSTPEAPEPPSQEQWAIPVDATSPVGDFYRLIP--QPAFQWA 308
Query: 341 HTCLTLNS-----VQERKNLIYSLPTSGGKTLVAE--ILMLQELLCCRKDVLMILPYVAI 393
++ ++ + TS GKT+VAE I + Q+ + + P A+
Sbjct: 309 FEPDVFQKQAILHLERHDSVFVAAHTSAGKTVVAEYAIALAQKHMT---RTIYTSPIKAL 365
Query: 394 VQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYIATIEKGHSLVNSLIETGR 453
+K + ++G + + + S I T E ++ S++ +G
Sbjct: 366 SNQKFRDFRNTFGDVGLLTGD----------VQLHPEASCLIMTTE----ILRSMLYSGS 411
Query: 454 --IDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTSKTTQIIGMSATLNNVEDLQKFL- 510
I L V+ DE+H I + RG E L + II +SAT+ N + ++
Sbjct: 412 DVIRDLEWVIFDEVHYINDVERGVVWEEVLIML---PDHVSIILLSATVPNALEFADWIG 468
Query: 511 -----QAEYYTSQFRPVELKEYL---KINDTIYEVDSKAENGMTFSRLLNY--------- 553
Q ++ RPV L+ YL + T E+ ++ F Y
Sbjct: 469 RLKRRQIYVISTVTRPVPLEHYLFTGNSSKTQGELFLLLDSRGAFHTKGYYAAVEAKKER 528
Query: 554 --KYSDTLKKMDPDH--------------LVALVTEVIPNYSCLVFCPSKKNCENVAEMI 597
K++ T P H L +L T +VF S+ C+ A +
Sbjct: 529 MSKHAQTFGAKQPTHQGGPAQDRGVYLSLLASLRTRA--QLPVVVFTFSRGRCDEQASGL 586
Query: 598 CKF----LSKEYLKHKEKEKCEVIKNLKNIGNGNLCPV---LKRTIPFGVAYHHSGLTSD 650
S++ H ++C + L+ G+ P + + G+ HHSG+
Sbjct: 587 TSLDLTTSSEKSEIHLFLQRC--LARLR--GSDRQLPQVLHMSELLNRGLGVHHSGILPI 642
Query: 651 ERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRA--PYVAKEF--LKRNQYKQMIG 706
++++E +S G++ + T T A GVN+PAR V+ + + F L +Y QM G
Sbjct: 643 LKEIVEMLFSRGLVKVLFATETFAMGVNMPARTVVFDSMRKHDGSTFRDLLPGEYVQMAG 702
Query: 707 RAGRAGIDTIGESILI 722
RAGR G+D G IL+
Sbjct: 703 RAGRRGLDPTGTVILL 718
>gi|149274648 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like [Homo
sapiens]
Length = 1706
Score = 62.0 bits (149), Expect = 3e-09
Identities = 37/119 (31%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 599 KFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEA 658
K L E ++K+ V+ ++ +G LK G+ YHHS + E++ +E
Sbjct: 1207 KALHTEITRNKDSTLERVLPRVRFTRHGK---ELKALAQRGIGYHHSSMYFKEKEFVEIL 1263
Query: 659 YSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIG 717
+ G++ + T T TLA G+++P + V+ V +L Y+QM GRAGR G D +G
Sbjct: 1264 FVKGLIRVVTATETLALGIHMPCKSVVFAQDSV---YLDALNYRQMSGRAGRRGQDLLG 1319
>gi|14591902 RecQ protein-like [Homo sapiens]
Length = 649
Score = 50.4 bits (119), Expect = 9e-06
Identities = 82/401 (20%), Positives = 144/401 (35%), Gaps = 83/401 (20%)
Query: 322 KVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCR 381
KV+D+ +EK Q T+N K + +PT GGK+L ++ LC
Sbjct: 78 KVKDILQNVFKLEKFRPLQLE--TINVTMAGKEVFLVMPTGGGKSLCYQL----PALCSD 131
Query: 382 KDVLMILPYVAIVQEKISGLSSFGIELGFF----VEEYAGSKGRFPPTKRREKKSLYIA- 436
L+I P ++++++++ L GI +E+ K E K +Y+
Sbjct: 132 GFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTP 191
Query: 437 -TIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTS-KTTQII 494
I K ++ L + + VDE+H + + IL +I
Sbjct: 192 EKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLI 251
Query: 495 GMSATLNN--VEDLQKFLQAE---YYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSR 549
G++AT N + D QK L E +T+ F L YEV K N F
Sbjct: 252 GLTATATNHVLTDAQKILCIEKCFTFTASFNRPNL---------YYEVRQKPSNTEDFI- 301
Query: 550 LLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHK 609
+ +V L+ S +++C S+K+ E
Sbjct: 302 ---------------EDIVKLINGRYKGQSGIIYCFSQKDSE------------------ 328
Query: 610 EKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTC 669
+V +L+N+G +H+ L +++ + +S + +
Sbjct: 329 -----QVTVSLQNLG-------------IHAGAYHANLEPEDKTTVHRKWSANEIQVVVA 370
Query: 670 TSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGR 710
T G++ P R ++ ++K Y Q GRAGR
Sbjct: 371 TVAFGMGIDKPDVRFVIHHS-MSKSM---ENYYQESGRAGR 407
>gi|14591904 RecQ protein-like [Homo sapiens]
Length = 649
Score = 50.4 bits (119), Expect = 9e-06
Identities = 82/401 (20%), Positives = 144/401 (35%), Gaps = 83/401 (20%)
Query: 322 KVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCR 381
KV+D+ +EK Q T+N K + +PT GGK+L ++ LC
Sbjct: 78 KVKDILQNVFKLEKFRPLQLE--TINVTMAGKEVFLVMPTGGGKSLCYQL----PALCSD 131
Query: 382 KDVLMILPYVAIVQEKISGLSSFGIELGFF----VEEYAGSKGRFPPTKRREKKSLYIA- 436
L+I P ++++++++ L GI +E+ K E K +Y+
Sbjct: 132 GFTLVICPLISLMEDQLMVLKQLGISATMLNASSSKEHVKWVHAEMVNKNSELKLIYVTP 191
Query: 437 -TIEKGHSLVNSLIETGRIDSLGLVVVDELHMIGEGSRGATLEMTLAKILYTS-KTTQII 494
I K ++ L + + VDE+H + + IL +I
Sbjct: 192 EKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLI 251
Query: 495 GMSATLNN--VEDLQKFLQAE---YYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSR 549
G++AT N + D QK L E +T+ F L YEV K N F
Sbjct: 252 GLTATATNHVLTDAQKILCIEKCFTFTASFNRPNL---------YYEVRQKPSNTEDFI- 301
Query: 550 LLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEMICKFLSKEYLKHK 609
+ +V L+ S +++C S+K+ E
Sbjct: 302 ---------------EDIVKLINGRYKGQSGIIYCFSQKDSE------------------ 328
Query: 610 EKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLFTC 669
+V +L+N+G +H+ L +++ + +S + +
Sbjct: 329 -----QVTVSLQNLG-------------IHAGAYHANLEPEDKTTVHRKWSANEIQVVVA 370
Query: 670 TSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGR 710
T G++ P R ++ ++K Y Q GRAGR
Sbjct: 371 TVAFGMGIDKPDVRFVIHHS-MSKSM---ENYYQESGRAGR 407
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 38.5 bits (88), Expect = 0.035
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 644 HSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQ 703
H+ T +R ++ G + + CT+ LA G++ +++ + +Y
Sbjct: 335 HAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSV----EYIH 390
Query: 704 MIGRAGRAGIDTIGESILILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTL 757
IGR GRAG G++I E DK +L + ++ V E+ KG Q L
Sbjct: 391 RIGRTGRAG--NKGKAITFFTEDDK-PLLRSVANVIQQA-GCPVPEYIKGFQKL 440
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 38.5 bits (88), Expect = 0.035
Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 8/114 (7%)
Query: 644 HSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQ 703
H+ T +R ++ G + + CT+ LA G++ +++ + +Y
Sbjct: 443 HAERTQQQRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSV----EYIH 498
Query: 704 MIGRAGRAGIDTIGESILILQEKDKQQVLELITKPLENCYSHLVQEFTKGIQTL 757
IGR GRAG G++I E DK +L + ++ V E+ KG Q L
Sbjct: 499 RIGRTGRAG--NKGKAITFFTEDDK-PLLRSVANVIQQA-GCPVPEYIKGFQKL 548
>gi|116812616 RecQ protein-like 4 [Homo sapiens]
Length = 1208
Score = 37.0 bits (84), Expect = 0.10
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 26/134 (19%)
Query: 579 SCLVFCPSKKNCENVAEMICKFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPF 638
S +++C +++ E +A ++ L ++ G+G P K T
Sbjct: 702 SIIIYCNRREDTERIAALLRTCLHAAWVP----------------GSGGRAP--KTT--- 740
Query: 639 GVAYHHSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFLKR 698
+H+G+ S ER+ ++ A+ G L + T G++ P R +L + F
Sbjct: 741 -AEAYHAGMCSRERRRVQRAFMQGQLRVVVATVAFGMGLDRPDVRAVLHLG-LPPSF--- 795
Query: 699 NQYKQMIGRAGRAG 712
Y Q +GRAGR G
Sbjct: 796 ESYVQAVGRAGRDG 809
>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
[Homo sapiens]
Length = 851
Score = 36.2 bits (82), Expect = 0.18
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 10/93 (10%)
Query: 644 HSGLTSDERKLLEEAYSTGVLCLFTCTSTLAAGVNLPARRVILR--APYVAKEFLKRNQY 701
H G+ +ER + + +S + CT A G++LP I++ AP E++ R
Sbjct: 559 HGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYIHR--- 615
Query: 702 KQMIGRAGRAGIDTIGESILILQEKDKQQVLEL 734
IGR R G G S+LIL + + V L
Sbjct: 616 ---IGRTARIGCH--GSSLLILAPSEAEYVNSL 643
>gi|148612816 RecQ protein-like 5 isoform 1 [Homo sapiens]
Length = 991
Score = 35.0 bits (79), Expect = 0.39
Identities = 90/430 (20%), Positives = 157/430 (36%), Gaps = 81/430 (18%)
Query: 322 KVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCR 381
+VR + G + T+ V+ K++ +PT GK+L ++ L +
Sbjct: 15 RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQL----PALLAK 70
Query: 382 KDVLMILPYVAIVQEKISGLSSFGIELGFFVEEY-AGSKGRFPPTKRREK---KSLYI-- 435
+++ P +A++Q+++ L + + + + A + REK K LYI
Sbjct: 71 GITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITP 130
Query: 436 --ATIEKGHSLVNSLIETGRIDSLGLVVVDELHMI---GEGSRGATLEMTLAKILYTSKT 490
A +NSL+ L +VVDE H + G R L + +
Sbjct: 131 EMAASSSFQPTLNSLVSR---HLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAP 187
Query: 491 TQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRL 550
+ +AT ED+ L + + F+ + L Y+V F L
Sbjct: 188 CVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANL-----FYDVQ--------FKEL 234
Query: 551 LNYKYSDTLKKMDPDHLVALVTEVIPNYS-C-LVFCPSKKNCENVA-EMICKFLSKEYLK 607
+ SD + L AL E S C +V+C +++ CE +A E+ C+ ++ +
Sbjct: 235 I----SDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAK--- 287
Query: 608 HKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLF 667
+H+GL + ER L++ + + +
Sbjct: 288 ----------------------------------AYHAGLKASERTLVQNDWMEEKVPVI 313
Query: 668 TCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKD 727
T + GV+ R + +AK Y Q GRAGR G + L D
Sbjct: 314 VATISFGMGVDKANVRFVAHW-NIAKSMA---GYYQESGRAGRDGKPSWCR--LYYSRND 367
Query: 728 KQQVLELITK 737
+ QV LI K
Sbjct: 368 RDQVSFLIRK 377
>gi|51242943 RecQ protein-like 5 isoform 3 [Homo sapiens]
Length = 410
Score = 35.0 bits (79), Expect = 0.39
Identities = 90/430 (20%), Positives = 157/430 (36%), Gaps = 81/430 (18%)
Query: 322 KVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCR 381
+VR + G + T+ V+ K++ +PT GK+L ++ L +
Sbjct: 15 RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQL----PALLAK 70
Query: 382 KDVLMILPYVAIVQEKISGLSSFGIELGFFVEEY-AGSKGRFPPTKRREK---KSLYI-- 435
+++ P +A++Q+++ L + + + + A + REK K LYI
Sbjct: 71 GITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITP 130
Query: 436 --ATIEKGHSLVNSLIETGRIDSLGLVVVDELHMI---GEGSRGATLEMTLAKILYTSKT 490
A +NSL+ L +VVDE H + G R L + +
Sbjct: 131 EMAASSSFQPTLNSLVSR---HLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAP 187
Query: 491 TQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRL 550
+ +AT ED+ L + + F+ + L Y+V F L
Sbjct: 188 CVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANL-----FYDVQ--------FKEL 234
Query: 551 LNYKYSDTLKKMDPDHLVALVTEVIPNYS-C-LVFCPSKKNCENVA-EMICKFLSKEYLK 607
+ SD + L AL E S C +V+C +++ CE +A E+ C+ ++ +
Sbjct: 235 I----SDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAK--- 287
Query: 608 HKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLF 667
+H+GL + ER L++ + + +
Sbjct: 288 ----------------------------------AYHAGLKASERTLVQNDWMEEKVPVI 313
Query: 668 TCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKD 727
T + GV+ R + +AK Y Q GRAGR G + L D
Sbjct: 314 VATISFGMGVDKANVRFVAHW-NIAKSMA---GYYQESGRAGRDGKPSWCR--LYYSRND 367
Query: 728 KQQVLELITK 737
+ QV LI K
Sbjct: 368 RDQVSFLIRK 377
>gi|51242947 RecQ protein-like 5 isoform 2 [Homo sapiens]
Length = 435
Score = 35.0 bits (79), Expect = 0.39
Identities = 90/430 (20%), Positives = 157/430 (36%), Gaps = 81/430 (18%)
Query: 322 KVRDLYAQFKGIEKLYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCR 381
+VR + G + T+ V+ K++ +PT GK+L ++ L +
Sbjct: 15 RVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQL----PALLAK 70
Query: 382 KDVLMILPYVAIVQEKISGLSSFGIELGFFVEEY-AGSKGRFPPTKRREK---KSLYI-- 435
+++ P +A++Q+++ L + + + + A + REK K LYI
Sbjct: 71 GITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITP 130
Query: 436 --ATIEKGHSLVNSLIETGRIDSLGLVVVDELHMI---GEGSRGATLEMTLAKILYTSKT 490
A +NSL+ L +VVDE H + G R L + +
Sbjct: 131 EMAASSSFQPTLNSLVSR---HLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAP 187
Query: 491 TQIIGMSATLNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEVDSKAENGMTFSRL 550
+ +AT ED+ L + + F+ + L Y+V F L
Sbjct: 188 CVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANL-----FYDVQ--------FKEL 234
Query: 551 LNYKYSDTLKKMDPDHLVALVTEVIPNYS-C-LVFCPSKKNCENVA-EMICKFLSKEYLK 607
+ SD + L AL E S C +V+C +++ CE +A E+ C+ ++ +
Sbjct: 235 I----SDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAK--- 287
Query: 608 HKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLEEAYSTGVLCLF 667
+H+GL + ER L++ + + +
Sbjct: 288 ----------------------------------AYHAGLKASERTLVQNDWMEEKVPVI 313
Query: 668 TCTSTLAAGVNLPARRVILRAPYVAKEFLKRNQYKQMIGRAGRAGIDTIGESILILQEKD 727
T + GV+ R + +AK Y Q GRAGR G + L D
Sbjct: 314 VATISFGMGVDKANVRFVAHW-NIAKSMA---GYYQESGRAGRDGKPSWCR--LYYSRND 367
Query: 728 KQQVLELITK 737
+ QV LI K
Sbjct: 368 RDQVSFLIRK 377
>gi|4826686 DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 [Homo sapiens]
Length = 740
Score = 34.7 bits (78), Expect = 0.51
Identities = 63/335 (18%), Positives = 133/335 (39%), Gaps = 69/335 (20%)
Query: 445 VNSLIETGRID--SLGLVVVDELH-MIGEGSRGATLEM--TLAKILYTSKTTQIIGMSAT 499
++ L+ TG+++ + +V+DE ++ +G M + ++ K Q+I SAT
Sbjct: 350 LDDLVSTGKLNLSQVRFLVLDEADGLLSQGYSDFINRMHNQIPQVTSDGKRLQVIVCSAT 409
Query: 500 LNNVEDLQKFLQAEYYTSQFRPVELKEYLKINDTIYEV---------------------- 537
L++ D++K + + + V+LK + DT++ V
Sbjct: 410 LHSF-DVKKLSEKIMHFPTW--VDLKGEDSVPDTVHHVVVPVNPKTDRLWERLGKSHIRT 466
Query: 538 -DSKAENGMTFSRLLNYKYSDTLKKMDPDHLVALVTEVIPNYSCLVFCPSKKNCENVAEM 596
D A++ +S+ +K + ++ V + E + + ++FC +K +C+N+ +
Sbjct: 467 DDVHAKDNTRPGANSPEMWSEAIKILKGEYAVRAIKEHKMDQA-IIFCRTKIDCDNLEQY 525
Query: 597 ICKFLSKEYLKHKEKEKCEVIKNLKNIGNGNLCPVLKRTIPFGVAYHHSGLTSDERKLLE 656
++ G + K+ F H ERK
Sbjct: 526 F----------------------IQQGGGPD-----KKGHQFSCVCLHGDRKPHERKQNL 558
Query: 657 EAYSTGVLCLFTCTSTLAAGVNLPARRVILRAPYVAKEFL--KRNQYKQMIGRAGRAGID 714
E + G + CT A G+++ PYV L ++ Y IGR GRA +
Sbjct: 559 ERFKKGDVRFLICTDVAARGIDIHG------VPYVINVTLPDEKQNYVHRIGRVGRA--E 610
Query: 715 TIGESILILQEKDKQQVLELITKPLENCYSHLVQE 749
+G +I ++ + ++ + + + CY+ ++E
Sbjct: 611 RMGLAISLVATEKEKVWYHVCSSRGKGCYNTRLKE 645
>gi|117500790 FERM domain containing 3 [Homo sapiens]
Length = 597
Score = 34.3 bits (77), Expect = 0.67
Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 13/117 (11%)
Query: 12 VSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLPVEVQPLLLSDS 71
V LPK S I +P A E D EEE+ + E P+ + L+ + S
Sbjct: 400 VPLPKEENISAPLISSSPVKAAREYEDPPSEEEDKIKEE---------PLTISELVYNPS 450
Query: 72 PECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQ 128
L D D+L P+ + + DS D+ D ++F IA+ ++L++
Sbjct: 451 ASLLPTPVDDDEIDMLFDCPSRLELEREDTDSFEDLEADENAF----LIAEEEELKE 503
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 33.9 bits (76), Expect = 0.87
Identities = 62/283 (21%), Positives = 112/283 (39%), Gaps = 38/283 (13%)
Query: 167 ELQTDKHTENQSGYEGVTIEPGADLLYDVPSSQAIYFEN--LQNSSNDLGDHSMKERDWK 224
E Q K + + + ++P ADL Y+ Q + EN L+N N+L +
Sbjct: 1171 EQQDSKKVQAEPPQTDIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVADQATQN 1230
Query: 225 SSSHNTVNE--------ELPHNCIEQPQQNDESSSKVRTSSDMNRRKSIKDHLKNAMTG- 275
+SSH + + +L H +E ++ S+D R +NA
Sbjct: 1231 NSSHGSPDSYSLLLNQLKLAHEELEVRKEEVLILRTQIVSADQRRLAG-----RNAEPNI 1285
Query: 276 NAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEK 335
NA++ P + +D + E S + D G + + ++ Y K + +
Sbjct: 1286 NARSSWPNSEKHVDQEDAI---EAYHGVCQTNSKTEDWG-YLNEDGELGLAYQGLKQVAR 1341
Query: 336 LYEWQHTCLTLNSVQERKNLIYSLPTSGGKTLVAEILMLQELLCCRKDVLMILPYVAI-- 393
L E Q +L +E ++L L + L E+ Q+ C L++ P +
Sbjct: 1342 LLEAQLQAQSLEHEEEVEHLKAQL-----EALKEEMDKQQQTFC---QTLLLSPEAQVEF 1393
Query: 394 -VQEKISGLSSFGIELGFFVEEYAGSKGRFPPTKRREKKSLYI 435
VQ++IS L++ ++L VE + +R+ KK L I
Sbjct: 1394 GVQQEISRLTNENLDLKELVE-------KLEKNERKLKKQLKI 1429
>gi|4506581 retinitis pigmentosa GTPase regulator isoform A [Homo
sapiens]
Length = 815
Score = 33.5 bits (75), Expect = 1.1
Identities = 51/238 (21%), Positives = 100/238 (42%), Gaps = 28/238 (11%)
Query: 85 DLLRHMPTDRGVGDQPNDSEVDMFGDYDSFTENSFIAQVDDLEQKYMQLPEHKKHATDFA 144
DL++ D + + ++E+D +S E + I + + M L ++K
Sbjct: 464 DLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHI----MSLNSNEK------ 513
Query: 145 TENLCSESIKNKLSITTIGNLTELQTDKHTENQSGYEGVT-IEPGADLLYDVPSSQAIYF 203
+L ++ + TIG LT+ ++ YE ++ ++ G V SQ I+
Sbjct: 514 --SLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHV--SQGIFM 569
Query: 204 ENLQNSSNDLGDHSMKERDWKSSSHNTVNEELPHNCIEQPQQNDESSSKVRTSSDMNRRK 263
+ D ++ + K + ++ + EQ + +E + KV RK
Sbjct: 570 TQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIE----EQEVEANEENVKVHGG-----RK 620
Query: 264 SIKDHLKNAMTGNAKAQTPIFSRSKQLKDTLLSEEINVAKKTVESSSNDLGPFYSLPS 321
+ L + +T KA+ FS++++LK + EEIN + VES +G S+P+
Sbjct: 621 EKTEILSDDLTD--KAEDHEFSKTEELKLEDVDEEINA--ENVESKKKTVGDDESVPT 674
>gi|118600971 transcription elongation factor A (SII)-like 6 [Homo
sapiens]
Length = 183
Score = 33.1 bits (74), Expect = 1.5
Identities = 28/87 (32%), Positives = 36/87 (41%), Gaps = 18/87 (20%)
Query: 32 AELEPGDEGKEEEEMVAENRRR-----------KTAGVLPVEVQPLLLSDSPECLVLGGG 80
AE EPGDEG+ E++ E + + K A E QP P G
Sbjct: 50 AEGEPGDEGQLEDKGSQEKQGKSEGEGKPQGEGKPASQAKPEGQPRAAEKRP------AG 103
Query: 81 DTNPDLLRHMPTDRGVGDQPNDSEVDM 107
D P + TDRG D P DS+ D+
Sbjct: 104 DYVPRKAKRK-TDRGTDDSPKDSQEDL 129
>gi|239747122 PREDICTED: hypothetical protein XP_002343916 [Homo
sapiens]
Length = 598
Score = 32.7 bits (73), Expect = 1.9
Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 6/65 (9%)
Query: 23 GCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLPVEVQPLLLSDSPECLVLGGGDT 82
GC G P A LE GDE + E +K AG+ + L D +CL LG
Sbjct: 62 GCDCGEPIAQRLEEGDEAFRQSEY------QKAAGLFRSTLARLAQPDRGQCLRLGNALA 115
Query: 83 NPDLL 87
D L
Sbjct: 116 RADRL 120
>gi|239746558 PREDICTED: hypothetical protein XP_002343788 [Homo
sapiens]
Length = 616
Score = 32.7 bits (73), Expect = 1.9
Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 6/65 (9%)
Query: 23 GCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLPVEVQPLLLSDSPECLVLGGGDT 82
GC G P A LE GDE + E +K AG+ + L D +CL LG
Sbjct: 80 GCDCGEPIAQRLEEGDEAFRQSEY------QKAAGLFRSTLARLAQPDRGQCLRLGNALA 133
Query: 83 NPDLL 87
D L
Sbjct: 134 RADRL 138
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 32.7 bits (73), Expect = 1.9
Identities = 54/265 (20%), Positives = 100/265 (37%), Gaps = 33/265 (12%)
Query: 2 DECGSRIRRRVSLPKRNRPSLGCIFGAPTAAELEPGDEGKEEEEMVAENRRRKTAGVLPV 61
D GS + RR PKR S+ I D +EE K A +L +
Sbjct: 58 DTSGSSVARRA--PKRQASSVVVI------------DSDSDEE---CHTHEEKKAKLLEI 100
Query: 62 EVQPLLLSDSPECLVLGGGDTNPDLLRHMPTDRGVGDQPNDSEV--DMFGDYDSFTENSF 119
+SPEC + P ++ + D D ND EV D D ++ +NS
Sbjct: 101 NSD----DESPECCHVKPAIQEPPIV--ISDDDNDDDNGNDLEVPDDNSDDSEAPDDNSD 154
Query: 120 IAQVDDLEQKYMQLPEHKKHATDFATENLCSESIKNKLSITTIGNLTELQTDKHTEN--- 176
++ D + P+ ++ +N + + S + + ++ +D ++++
Sbjct: 155 DSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDV 214
Query: 177 ---QSGYEGVTIEPGADLLYDVPSSQAIYFENLQNSSNDLGDHSMKERDWKSSSHNTVNE 233
+S V + D DVP + E +SS+D D ++ ++ +
Sbjct: 215 PDDKSDDSDVPDDSSDDS--DVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDS 272
Query: 234 ELPHNCIEQPQQNDESSSKVRTSSD 258
E P + + + +D+SS S D
Sbjct: 273 EAPDDSSDDSEASDDSSDDSEASDD 297
>gi|55956801 SWI/SNF related, matrix associated, actin dependent
regulator of chromatin, subfamily b, member 1 isoform b
[Homo sapiens]
Length = 376
Score = 31.6 bits (70), Expect = 4.3
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 3/74 (4%)
Query: 303 KKTVESSSNDLGPFYSLPSKVRDLYAQFKGIEKLYE-WQHTCLTLNSVQERKNLIYSLPT 361
+K V+ D G FY + S+V + F+G LY+ + L +V+ERK ++ S
Sbjct: 12 QKPVKFQLEDDGEFYMIGSEVGNYLRMFRG--SLYKRYPSLWRRLATVEERKKIVASSHD 69
Query: 362 SGGKTLVAEILMLQ 375
G TL + +L+
Sbjct: 70 HGYTTLATSVTLLK 83
>gi|55749431 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 31.6 bits (70), Expect = 4.3
Identities = 28/86 (32%), Positives = 34/86 (39%), Gaps = 18/86 (20%)
Query: 33 ELEPGDEGKEEEEMVAENRRR-----------KTAGVLPVEVQPLLLSDSPECLVLGGGD 81
E EPGDEG+ E+E E + R K A E QP P D
Sbjct: 51 EGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRP------AED 104
Query: 82 TNPDLLRHMPTDRGVGDQPNDSEVDM 107
P + TDRG D P DS+ D+
Sbjct: 105 YVPRKAKRK-TDRGTDDSPKDSQEDL 129
>gi|14249718 transcription elongation factor A (SII)-like 3 [Homo
sapiens]
Length = 200
Score = 31.6 bits (70), Expect = 4.3
Identities = 28/86 (32%), Positives = 34/86 (39%), Gaps = 18/86 (20%)
Query: 33 ELEPGDEGKEEEEMVAENRRR-----------KTAGVLPVEVQPLLLSDSPECLVLGGGD 81
E EPGDEG+ E+E E + R K A E QP P D
Sbjct: 51 EGEPGDEGQLEDEGSQEKQGRSEGEGKPQGEGKPASQAKPESQPRAAEKRP------AED 104
Query: 82 TNPDLLRHMPTDRGVGDQPNDSEVDM 107
P + TDRG D P DS+ D+
Sbjct: 105 YVPRKAKRK-TDRGTDDSPKDSQEDL 129
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,487,972
Number of Sequences: 37866
Number of extensions: 1726478
Number of successful extensions: 5236
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 5165
Number of HSP's gapped (non-prelim): 65
length of query: 1101
length of database: 18,247,518
effective HSP length: 113
effective length of query: 988
effective length of database: 13,968,660
effective search space: 13801036080
effective search space used: 13801036080
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.