Search of human proteins with 11038643

Search of human proteins with 11038643

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11038643 adaptor-related protein complex 2, sigma 1 subunit
isoform AP17delta [Homo sapiens]
         (104 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11038643 adaptor-related protein complex 2, sigma 1 subunit i...   209   5e-55
gi|70906430 adaptor-related protein complex 2, sigma 1 subunit i...   190   2e-49
gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [H...    83   5e-17
gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [H...    80   3e-16
gi|88703051 adaptor-related protein complex 1, sigma 3 subunit [...    80   3e-16
gi|189409104 adaptor-related protein complex 4, sigma 1 subunit ...    71   2e-13
gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [H...    67   3e-12
gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [H...    61   2e-10
gi|21361394 adaptor-related protein complex 4, sigma 1 subunit i...    42   8e-05
gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo...    32   0.11 
gi|194473724 adaptor-related protein complex 1, mu 1 subunit iso...    30   0.53 
gi|14210504 adaptor-related protein complex 1, mu 1 subunit isof...    30   0.53 
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]                    29   0.91 
gi|91208426 U5 snRNP-specific protein [Homo sapiens]                   28   1.5  
gi|68799814 adaptor-related protein complex 2, mu 1 subunit isof...    28   1.5  
gi|14917109 adaptor-related protein complex 2, mu 1 subunit isof...    28   1.5  
gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]     28   2.0  
gi|4557511 death-associated protein kinase 3 [Homo sapiens]            27   4.5  
gi|21955154 NLR family, pyrin domain containing 12 isoform 2 [Ho...    27   4.5  
gi|21361875 LTV1 homolog [Homo sapiens]                                26   7.7  

>gi|11038643 adaptor-related protein complex 2, sigma 1 subunit
           isoform AP17delta [Homo sapiens]
          Length = 104

 Score =  209 bits (531), Expect = 5e-55
 Identities = 104/104 (100%), Positives = 104/104 (100%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLNEYFHNV 60
           MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLNEYFHNV
Sbjct: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLNEYFHNV 60

Query: 61  CELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 104
           CELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE
Sbjct: 61  CELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 104


>gi|70906430 adaptor-related protein complex 2, sigma 1 subunit
           isoform AP17 [Homo sapiens]
          Length = 142

 Score =  190 bits (482), Expect = 2e-49
 Identities = 104/142 (73%), Positives = 104/142 (73%), Gaps = 38/142 (26%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHT------------- 47
           MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHT             
Sbjct: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYR 60

Query: 48  -------------------------NFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA 82
                                    NFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA
Sbjct: 61  RYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA 120

Query: 83  GEIRETSQTKVLKQLLMLQSLE 104
           GEIRETSQTKVLKQLLMLQSLE
Sbjct: 121 GEIRETSQTKVLKQLLMLQSLE 142


>gi|4557471 adaptor-related protein complex 1, sigma 1 subunit [Homo
           sapiens]
          Length = 158

 Score = 82.8 bits (203), Expect = 5e-17
 Identities = 44/135 (32%), Positives = 70/135 (51%), Gaps = 38/135 (28%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNF----------- 49
           M+RF+L+ +R GK RL KWY+   D E++K++ E+  VV  R  K  +F           
Sbjct: 1   MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYK 60

Query: 50  ---------------------------VEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA 82
                                      VE+L++YF +VCELD++FNF K Y ++DE  + 
Sbjct: 61  RYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLMG 120

Query: 83  GEIRETSQTKVLKQL 97
           G++++TS+  VLK +
Sbjct: 121 GDVQDTSKKSVLKAI 135


>gi|22027655 adaptor-related protein complex 1 sigma 2 subunit [Homo
           sapiens]
          Length = 157

 Score = 80.5 bits (197), Expect = 3e-16
 Identities = 45/134 (33%), Positives = 67/134 (50%), Gaps = 38/134 (28%)

Query: 2   IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNF------------ 49
           ++F+L+ +R GK RL KWY+   D EK+K+  E+   V  R  K  +F            
Sbjct: 1   MQFMLLFSRQGKLRLQKWYVPLSDKEKKKITRELVQTVLARKPKMCSFLEWRDLKIVYKR 60

Query: 50  --------------------------VEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAG 83
                                     VE+L++YF +VCELD++FNF K Y ++DE  L G
Sbjct: 61  YASLYFCCAIEDQDNELITLEIIHRYVELLDKYFGSVCELDIIFNFEKAYFILDEFLLGG 120

Query: 84  EIRETSQTKVLKQL 97
           E++ETS+  VLK +
Sbjct: 121 EVQETSKKNVLKAI 134


>gi|88703051 adaptor-related protein complex 1, sigma 3 subunit
           [Homo sapiens]
          Length = 154

 Score = 80.5 bits (197), Expect = 3e-16
 Identities = 44/135 (32%), Positives = 68/135 (50%), Gaps = 38/135 (28%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFV---------- 50
           MI FIL+ +R GK RL KWY+   D E++K+  E+  ++  R  + ++FV          
Sbjct: 1   MIHFILLFSRQGKLRLQKWYITLPDKERKKITREIVQIILSRGHRTSSFVDWKELKLVYK 60

Query: 51  ----------------------------EVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA 82
                                       E+L++YF NVCELD++FNF K Y ++DE  + 
Sbjct: 61  RYASLYFCCAIENQDNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIG 120

Query: 83  GEIRETSQTKVLKQL 97
           GEI+ETS+   +K +
Sbjct: 121 GEIQETSKKIAVKAI 135


>gi|189409104 adaptor-related protein complex 4, sigma 1 subunit
           isoform 2 [Homo sapiens]
          Length = 144

 Score = 71.2 bits (173), Expect = 2e-13
 Identities = 48/141 (34%), Positives = 71/141 (50%), Gaps = 38/141 (26%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEV------------------------- 35
           MI+F L+ N+ G+TRL+K+Y   D +++  L  EV                         
Sbjct: 1   MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYR 60

Query: 36  -----HAVVTVRDAKHT--------NFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLA 82
                  VV V D ++         NFVEVL+EYF  V ELD++FN  KV+ ++DEM L 
Sbjct: 61  QYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEMVLN 120

Query: 83  GEIRETSQTKVLKQLLMLQSL 103
           G I ET++ ++L  LL+L  +
Sbjct: 121 GCIVETNRARILAPLLILDKM 141


>gi|4502861 adaptor-related protein complex 3, sigma 1 subunit [Homo
           sapiens]
          Length = 193

 Score = 67.0 bits (162), Expect = 3e-12
 Identities = 43/148 (29%), Positives = 67/148 (45%), Gaps = 44/148 (29%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNF----------- 49
           MI+ ILI N  GK RL+K+Y  + +D +Q++I E   +V+ RD    NF           
Sbjct: 1   MIKAILIFNNHGKPRLSKFYQPYSEDTQQQIIRETFHLVSKRDENVCNFLEGGLLIGGSD 60

Query: 50  ---------------------------------VEVLNEYFHNVCELDLVFNFYKVYTVV 76
                                            VE L++ F NVCELDL+F+  KV+ ++
Sbjct: 61  NKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHVDKVHNIL 120

Query: 77  DEMFLAGEIRETSQTKVLKQLLMLQSLE 104
            EM + G + ET+  +++ Q+     LE
Sbjct: 121 AEMVMGGMVLETNMNEIVTQIDAQNKLE 148


>gi|5031581 adaptor-related protein complex 3, sigma 2 subunit [Homo
           sapiens]
          Length = 193

 Score = 61.2 bits (147), Expect = 2e-10
 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 44/148 (29%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNF----------- 49
           MI+ IL+ N  GK RL ++Y +F ++ +Q+++ E   +V  RD    NF           
Sbjct: 1   MIQAILVFNNHGKPRLVRFYQRFPEEIQQQIVRETFHLVLKRDDNICNFLEGGSLIGGSD 60

Query: 50  ---------------------------------VEVLNEYFHNVCELDLVFNFYKVYTVV 76
                                            VE L++ F NVCELDL+F+  KV+ ++
Sbjct: 61  YKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHMDKVHYIL 120

Query: 77  DEMFLAGEIRETSQTKVLKQLLMLQSLE 104
            E+ + G + ET+  +++ Q+     LE
Sbjct: 121 QEVVMGGMVLETNMNEIVAQIEAQNRLE 148


>gi|21361394 adaptor-related protein complex 4, sigma 1 subunit
           isoform 1 [Homo sapiens]
          Length = 159

 Score = 42.4 bits (98), Expect = 8e-05
 Identities = 33/105 (31%), Positives = 46/105 (43%), Gaps = 38/105 (36%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEV------------------------- 35
           MI+F L+ N+ G+TRL+K+Y   D +++  L  EV                         
Sbjct: 1   MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYR 60

Query: 36  -----HAVVTVRDAKHT--------NFVEVLNEYFHNVCELDLVF 67
                  VV V D ++         NFVEVL+EYF  V ELD+ F
Sbjct: 61  QYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDVSF 105


>gi|9506797 adaptor-related protein complex 1, mu 2 subunit [Homo
           sapiens]
          Length = 423

 Score = 32.0 bits (71), Expect = 0.11
 Identities = 18/53 (33%), Positives = 31/53 (58%), Gaps = 1/53 (1%)

Query: 50  VEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQS 102
           +EV  EYF  + E  +  NF  VY ++DE+   G   +T+ +K+L++ +  QS
Sbjct: 88  IEVFCEYFKELEEESIRDNFVIVYELLDELMDFG-FPQTTDSKILQEYITQQS 139


>gi|194473724 adaptor-related protein complex 1, mu 1 subunit
           isoform 1 [Homo sapiens]
          Length = 435

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 15/49 (30%), Positives = 30/49 (61%), Gaps = 1/49 (2%)

Query: 50  VEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLL 98
           V+V +EYF  + E  +  NF  +Y ++DE+   G   +T+ +K+L++ +
Sbjct: 88  VQVFSEYFKELEEESIRDNFVIIYELLDELMDFG-YPQTTDSKILQEYI 135


>gi|14210504 adaptor-related protein complex 1, mu 1 subunit isoform
           2 [Homo sapiens]
          Length = 423

 Score = 29.6 bits (65), Expect = 0.53
 Identities = 15/49 (30%), Positives = 30/49 (61%), Gaps = 1/49 (2%)

Query: 50  VEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLL 98
           V+V +EYF  + E  +  NF  +Y ++DE+   G   +T+ +K+L++ +
Sbjct: 88  VQVFSEYFKELEEESIRDNFVIIYELLDELMDFG-YPQTTDSKILQEYI 135


>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
          Length = 292

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 8  QNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLNEYFHNVCELDLVF 67
          +NR     +A   ++ DDD++      +  +  +++ KH N V  L++  H+  +L LVF
Sbjct: 22 KNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVR-LHDVLHSDKKLTLVF 80

Query: 68 NF 69
           F
Sbjct: 81 EF 82


>gi|91208426 U5 snRNP-specific protein [Homo sapiens]
          Length = 2335

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 12/50 (24%), Positives = 27/50 (54%), Gaps = 2/50 (4%)

Query: 7    IQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLNEY 56
            +QN   K R A+ +++ DD+  Q+    V  ++    +  T F +++N++
Sbjct: 1216 LQNEVTKERTAQCFLRVDDESMQRFHNRVRQILMASGS--TTFTKIVNKW 1263


>gi|68799814 adaptor-related protein complex 2, mu 1 subunit isoform
           b [Homo sapiens]
          Length = 433

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 15/54 (27%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 51  EVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 104
           +V+  YF  + E ++  NF  +Y ++DE+   G   + S+T  LK  +  Q ++
Sbjct: 87  DVMAAYFGKISEENIKNNFVLIYELLDEILDFG-YPQNSETGALKTFITQQGIK 139


>gi|14917109 adaptor-related protein complex 2, mu 1 subunit isoform
           a [Homo sapiens]
          Length = 435

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 15/54 (27%), Positives = 29/54 (53%), Gaps = 1/54 (1%)

Query: 51  EVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE 104
           +V+  YF  + E ++  NF  +Y ++DE+   G   + S+T  LK  +  Q ++
Sbjct: 87  DVMAAYFGKISEENIKNNFVLIYELLDEILDFG-YPQNSETGALKTFITQQGIK 139


>gi|91206450 ankyrin and armadillo repeat containing [Homo sapiens]
          Length = 1363

 Score = 27.7 bits (60), Expect = 2.0
 Identities = 18/58 (31%), Positives = 26/58 (44%)

Query: 1   MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLNEYFH 58
           +I F+L   +  K       +Q   D+K K   E+   +  RD K  NF    N+YFH
Sbjct: 251 LIPFLLSLKKKMKVPYLSSLLQPFSDDKVKTERELPPFIYGRDFKCQNFHYKENQYFH 308


>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
          Length = 454

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 17/67 (25%), Positives = 32/67 (47%), Gaps = 2/67 (2%)

Query: 33  EEVHAVVTV-RDAKHTNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQT 91
           EE+   V + R+ +H N +  L++ F N  ++ L+        + D +     + E   T
Sbjct: 59  EEIEREVNILREIRHPNII-TLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEAT 117

Query: 92  KVLKQLL 98
           + LKQ+L
Sbjct: 118 QFLKQIL 124


>gi|21955154 NLR family, pyrin domain containing 12 isoform 2 [Homo
           sapiens]
          Length = 1061

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 27/114 (23%), Positives = 45/114 (39%), Gaps = 38/114 (33%)

Query: 28  KQKLIEEVHAVVTVRDA---------KHTNFVEVLN-----------EYFHNVCELDLVF 67
           ++KL+ E+  ++T R           +H   VE+L            +YFHN  +   VF
Sbjct: 329 RKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVF 388

Query: 68  NFYK-----------------VYTVVDEMFLAGE-IRETSQTKVLKQLLMLQSL 103
           N+ +                 V T + +    G  +R+TS+T     +L L SL
Sbjct: 389 NYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSL 442


>gi|21361875 LTV1 homolog [Homo sapiens]
          Length = 475

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 6/85 (7%)

Query: 15  RLAKWYMQFDDDEKQKLIE-EVHAVVTVRDAKHTNFVEVLNEYFHNVCELDLVFNFYKVY 73
           R  K+Y Q+DDDE   L   E+   + V         EVLN+Y+    E  +  N   + 
Sbjct: 262 RFEKFYEQYDDDEIGALDNAELEGSIQV---DSNRLQEVLNDYYKEKAENCVKLN--TLE 316

Query: 74  TVVDEMFLAGEIRETSQTKVLKQLL 98
            + D+     E+ E+ + +++  +L
Sbjct: 317 PLEDQDLPMNELDESEEEEMITVVL 341


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.138    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,035,701
Number of Sequences: 37866
Number of extensions: 104578
Number of successful extensions: 401
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 381
Number of HSP's gapped (non-prelim): 28
length of query: 104
length of database: 18,247,518
effective HSP length: 75
effective length of query: 29
effective length of database: 15,407,568
effective search space: 446819472
effective search space used: 446819472
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.