Search of human proteins with 156105699

Search of human proteins with 156105699

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|156105699 ring finger and CCCH-type zinc finger domains 2
isoform 2 [Homo sapiens]
         (1064 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|156105699 ring finger and CCCH-type zinc finger domains 2 iso...  2149   0.0  
gi|156105697 ring finger and CCCH-type zinc finger domains 2 iso...  2099   0.0  
gi|73695473 roquin [Homo sapiens]                                     996   0.0  
gi|47132519 Ras association and pleckstrin homology domains 1 is...    51   5e-06
gi|50345997 E1A binding protein p300 [Homo sapiens]                    50   9e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    50   1e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    50   1e-05
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          50   1e-05
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          50   1e-05
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          50   1e-05
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    50   1e-05
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         49   3e-05
gi|239741653 PREDICTED: hypothetical protein XP_002342271 [Homo ...    49   3e-05
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    49   3e-05
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ...    48   4e-05
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    48   6e-05
gi|222446607 SH3 domain containing ring finger 2 [Homo sapiens]        48   6e-05
gi|116284392 mucin 2 precursor [Homo sapiens]                          47   1e-04
gi|11386183 WAS protein family, member 2 [Homo sapiens]                47   1e-04
gi|153791514 tripartite motif-containing 32 [Homo sapiens]             47   1e-04
gi|153792582 tripartite motif-containing 32 [Homo sapiens]             47   1e-04
gi|151301154 mucin 6, gastric [Homo sapiens]                           47   1e-04
gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]         47   1e-04
gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]           47   1e-04
gi|27436877 tripartite motif-containing 59 [Homo sapiens]              47   1e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    45   3e-04
gi|209862787 hypothetical protein LOC100191040 [Homo sapiens]          45   3e-04
gi|157168329 formin 1 [Homo sapiens]                                   45   5e-04
gi|221139926 NHS-like 1 [Homo sapiens]                                 45   5e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   6e-04

>gi|156105699 ring finger and CCCH-type zinc finger domains 2 isoform
            2 [Homo sapiens]
          Length = 1064

 Score = 2149 bits (5569), Expect = 0.0
 Identities = 1064/1064 (100%), Positives = 1064/1064 (100%)

Query: 1    MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD 60
            MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
Sbjct: 1    MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD 60

Query: 61   IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS 120
            IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS
Sbjct: 61   IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS 120

Query: 121  LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL 180
            LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
Sbjct: 121  LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL 180

Query: 181  WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG 240
            WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG
Sbjct: 181  WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG 240

Query: 241  HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW 300
            HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW
Sbjct: 241  HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW 300

Query: 301  SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI 360
            SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI
Sbjct: 301  SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI 360

Query: 361  DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR 420
            DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR
Sbjct: 361  DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR 420

Query: 421  QQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVI 480
            QQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVI
Sbjct: 421  QQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVI 480

Query: 481  GSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGANGQNAAGPSAD 540
            GSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGANGQNAAGPSAD
Sbjct: 481  GSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGANGQNAAGPSAD 540

Query: 541  SVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQ 600
            SVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQ
Sbjct: 541  SVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQ 600

Query: 601  DPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYST 660
            DPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYST
Sbjct: 601  DPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYST 660

Query: 661  FSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPM 720
            FSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPM
Sbjct: 661  FSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPM 720

Query: 721  DVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPD 780
            DVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPD
Sbjct: 721  DVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPD 780

Query: 781  QWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRADFSESVSGTKFEEDHLSHYSPWS 840
            QWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRADFSESVSGTKFEEDHLSHYSPWS
Sbjct: 781  QWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRADFSESVSGTKFEEDHLSHYSPWS 840

Query: 841  CGTIGSCINAIDSEPKDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGP 900
            CGTIGSCINAIDSEPKDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGP
Sbjct: 841  CGTIGSCINAIDSEPKDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGP 900

Query: 901  IISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATS 960
            IISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATS
Sbjct: 901  IISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATS 960

Query: 961  SAHYVERDRFIVTDLSGHRKHSSTGDLLSLELQQAKSNSLLLQREANALAMQQKWNSLDE 1020
            SAHYVERDRFIVTDLSGHRKHSSTGDLLSLELQQAKSNSLLLQREANALAMQQKWNSLDE
Sbjct: 961  SAHYVERDRFIVTDLSGHRKHSSTGDLLSLELQQAKSNSLLLQREANALAMQQKWNSLDE 1020

Query: 1021 GRHLTLNLLSKEIELRNGEVKKLNLSASCLMYLFSAAASWLYHY 1064
            GRHLTLNLLSKEIELRNGEVKKLNLSASCLMYLFSAAASWLYHY
Sbjct: 1021 GRHLTLNLLSKEIELRNGEVKKLNLSASCLMYLFSAAASWLYHY 1064


>gi|156105697 ring finger and CCCH-type zinc finger domains 2 isoform
            1 [Homo sapiens]
          Length = 1191

 Score = 2099 bits (5439), Expect = 0.0
 Identities = 1039/1041 (99%), Positives = 1041/1041 (100%)

Query: 1    MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD 60
            MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD
Sbjct: 1    MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD 60

Query: 61   IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS 120
            IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS
Sbjct: 61   IDVLPVNFALLQLVGAQVPDHQSIKLSNLGENKHYEVAKKCVEDLALYLKPLSGGKGVAS 120

Query: 121  LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL 180
            LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL
Sbjct: 121  LNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLSANL 180

Query: 181  WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG 240
            WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG
Sbjct: 181  WAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIG 240

Query: 241  HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW 300
            HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW
Sbjct: 241  HVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISPEQW 300

Query: 301  SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI 360
            SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI
Sbjct: 301  SSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELLANI 360

Query: 361  DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR 420
            DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR
Sbjct: 361  DPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCRDLR 420

Query: 421  QQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVI 480
            QQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVI
Sbjct: 421  QQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVISVI 480

Query: 481  GSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGANGQNAAGPSAD 540
            GSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGANGQNAAGPSAD
Sbjct: 481  GSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGANGQNAAGPSAD 540

Query: 541  SVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQ 600
            SVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQ
Sbjct: 541  SVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQ 600

Query: 601  DPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYST 660
            DPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYST
Sbjct: 601  DPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYST 660

Query: 661  FSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPM 720
            FSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPM
Sbjct: 661  FSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPM 720

Query: 721  DVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPD 780
            DVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPD
Sbjct: 721  DVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPD 780

Query: 781  QWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRADFSESVSGTKFEEDHLSHYSPWS 840
            QWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRADFSESVSGTKFEEDHLSHYSPWS
Sbjct: 781  QWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRADFSESVSGTKFEEDHLSHYSPWS 840

Query: 841  CGTIGSCINAIDSEPKDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGP 900
            CGTIGSCINAIDSEPKDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGP
Sbjct: 841  CGTIGSCINAIDSEPKDVIANSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGP 900

Query: 901  IISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATS 960
            IISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATS
Sbjct: 901  IISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVSDYVPYVNAVDSRWSSYGNEATS 960

Query: 961  SAHYVERDRFIVTDLSGHRKHSSTGDLLSLELQQAKSNSLLLQREANALAMQQKWNSLDE 1020
            SAHYVERDRFIVTDLSGHRKHSSTGDLLSLELQQAKSNSLLLQREANALAMQQKWNSLDE
Sbjct: 961  SAHYVERDRFIVTDLSGHRKHSSTGDLLSLELQQAKSNSLLLQREANALAMQQKWNSLDE 1020

Query: 1021 GRHLTLNLLSKEIELRNGEVK 1041
            GRHLTLNLLSKEIELRNGE++
Sbjct: 1021 GRHLTLNLLSKEIELRNGELQ 1041


>gi|73695473 roquin [Homo sapiens]
          Length = 1133

 Score =  996 bits (2574), Expect = 0.0
 Identities = 592/1098 (53%), Positives = 723/1098 (65%), Gaps = 98/1098 (8%)

Query: 1    MPVQAAQWTEFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKACPFDQTAINTD 60
            MPVQA QWT+FLSCPIC   FDE + KPISLGC HTVCK CLNKLHRKACPFDQT INTD
Sbjct: 1    MPVQAPQWTDFLSCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKACPFDQTTINTD 60

Query: 61   IDVLPVNFALLQLVGAQVPDHQSIKL-SNLGENKHYEVAKKCVEDLALYLKPLSGGKGVA 119
            I++LPVN ALLQLVGAQVP+ Q I L S + + KHYE AKKCVE+LALYLKPLS  +GV 
Sbjct: 61   IELLPVNSALLQLVGAQVPEQQPITLCSGVEDTKHYEEAKKCVEELALYLKPLSSARGVG 120

Query: 120  --SLNQSALSRPMQRKLVTLVNCQLVEEEGRVRAMRAARSLGERTVTELILQHQNPQQLS 177
              S  QS LSRPMQRKLVTLV+CQLVEEEGR+RAMRAARSLGERTVTELILQHQNPQQLS
Sbjct: 121  LNSTTQSVLSRPMQRKLVTLVHCQLVEEEGRIRAMRAARSLGERTVTELILQHQNPQQLS 180

Query: 178  ANLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT 237
            +NLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT
Sbjct: 181  SNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKT 240

Query: 238  SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAMEAGLRISP 297
            SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFR+YEALRREHD+QIV IAMEAGLRI+P
Sbjct: 241  SIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYEALRREHDSQIVQIAMEAGLRIAP 300

Query: 298  EQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLRPHLELL 357
            +QWSSLLYGD +HKSHMQSIIDKLQ+P SFA+SVQELTI LQRTGDPANLNRLRPHLELL
Sbjct: 301  DQWSSLLYGDQSHKSHMQSIIDKLQTPASFAQSVQELTIALQRTGDPANLNRLRPHLELL 360

Query: 358  ANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSKYKTSMCR 417
            ANIDP+PDA  PTWEQLEN +VAV+TVVHGLVD+IQN+S+KG +  QP  +SKYKT MCR
Sbjct: 361  ANIDPSPDAPPPTWEQLENGLVAVRTVVHGLVDYIQNHSKKGADQQQPPQHSKYKTYMCR 420

Query: 418  DLRQQGGCPRGTNCTFAHSQEELEKYRLRNKKINATVRTFPLLNKVGVNNTVTTTAGNVI 477
            D++Q+GGCPRG +CTFAHSQEELEK+R  NK++   V   PL   +G  N V   +  ++
Sbjct: 421  DMKQRGGCPRGASCTFAHSQEELEKFRKMNKRL---VPRRPLSASLGQLNEVGLPSAAIL 477

Query: 478  SVIGSTETTGKIVPS-TNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGANGQNAAG 536
               G+ +   +  P+  NGI +  N+V+QLI R TD    + ++  K GK+     +A G
Sbjct: 478  PDEGAVDLPSRKPPALPNGIVSTGNTVTQLIPRGTDP---SYDSSLKPGKIDHLSSSAPG 534

Query: 537  PSADSVTENKIGSPPKTPVSNVAATSAGPSN-----VGTELNSVPQKSSPFLTRVPVYPP 591
               D + E+   S    PV+  +    GP++     V   L  VP+ S        +YP 
Sbjct: 535  SPPD-LLESVPKSISALPVNPHSIPPRGPADLPPMPVTKPLQMVPRGSQ-------LYPA 586

Query: 592  HSENIQYFQDPR-TQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPA 650
               ++ Y+QDPR    PFE   Y Q  YY PPP        CV RFVR    P  S P  
Sbjct: 587  QQTDV-YYQDPRGAAPPFEPAPYQQGMYYTPPP-------QCVSRFVR----PPPSAPEP 634

Query: 651  SMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDD 710
            + PY DHY  +  ++R+ +S Y   P Q     PP+    Y   YD RR++  P Y R++
Sbjct: 635  APPYLDHYPPYL-QERVVNSQYGTQPQQ----YPPI----YPSHYDGRRVYPAPSYTREE 685

Query: 711  IIRSNSLPPMDVMHSSV--YQTSLRERYNSLDGYYSVACQP----PS----EPRTTVPLP 760
            I R + + P+++  ++V  Y    RERY  ++ YY VA  P    PS     P + +P P
Sbjct: 686  IFRESPI-PIEIPPAAVPSYVPESRERYQQIESYYPVAPHPTQIRPSYLREPPYSRLPPP 744

Query: 761  REPCGHLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTLPVATQSPTPPSPLFSVDFRADFS 820
             +P      S +E  RR+ +  AQ   +K   V S  P A  SPT P P F  +   D  
Sbjct: 745  PQP----HPSLDELHRRRKEIMAQLEERK---VISPPPFA-PSPTLP-PTFHPEEFLDED 795

Query: 821  ESVSGTKFEEDHLSHYSPWSCGTIGSCINAIDSEPKDVIANSNAVLMDLDSGDVKRRVHL 880
              V+G K++ +  S YSPWSC TIGS I   D++PKDV+A  +  +M+++S  +  R   
Sbjct: 796  LKVAG-KYKGNDYSQYSPWSCDTIGSYIGTKDAKPKDVVAAGSVEMMNVESKGM--RDQR 852

Query: 881  FETQRRTKE--EDPIIPFSDGPIISKWGAISRSSRTGYHTTDPVQATASQGSATKPISVS 938
             + QRR  E  +D +IPF D P +S++GAISR+S+T Y    P+QA A QG+ TK I++S
Sbjct: 853  LDLQRRAAETSDDDLIPFGDRPTVSRFGAISRTSKTIYQGAGPMQAMAPQGAPTKSINIS 912

Query: 939  DYVPYVNAVDSRWSSYG--NEATSSAHYVERDRFIVTDLSGHRK--HSSTGDLLSLELQQ 994
            DY PY        S Y       S  H+ ER+R  +++++ H K   S+  + L LELQQ
Sbjct: 913  DYSPYGTHGGWGASPYSPHQNIPSQGHFSERERISMSEVASHGKPLPSAEREQLRLELQQ 972

Query: 995  ---------------AKSNSLLLQREANALAMQQ--------KWNSLDEGRHLTLNLLSK 1031
                           A SN L+LQREAN LA Q         KW  +     L+L L   
Sbjct: 973  LNHQISQQTQLRGLEAVSNRLVLQREANTLAGQSQPPPPPPPKWPGMISSEQLSLELHQV 1032

Query: 1032 EIELRNGEVKKLNLSASC 1049
            E E+     ++L++   C
Sbjct: 1033 EREI-GKRTRELSMENQC 1049


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 57/214 (26%), Positives = 80/214 (37%), Gaps = 46/214 (21%)

Query: 580  SPFLTRVPVYPPHSENIQYF-----QDPRTQIPFEVPQYPQTGYYPPPPT---------- 624
            SP    VPV PP     Q F       P + +P  V Q      +PPPPT          
Sbjct: 827  SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI--ASQFPPPPTPPAMESQPLK 884

Query: 625  -VPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPV 683
             VPA VAP  P  V++    + S  P   P       F P    +S  + PPPP P    
Sbjct: 885  PVPANVAPQSPPAVKAKPKWQPSSIPVPSP------DFPPPPPESSLVFPPPPPSPVPAP 938

Query: 684  PPVPSGMYAPVYD-----SRRIWR---------PPMYQRDDIIRSNSLPPMDVMHSSVYQ 729
            PP P    +P  D      ++  +         PP  QR+  I+S+S         + + 
Sbjct: 939  PPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS--------GAEHP 990

Query: 730  TSLRERYNSLDGYYSVACQPPSEPRTTVPLPREP 763
               R   +SL   ++   +  S  + T+P P  P
Sbjct: 991  EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAP 1024



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 63/275 (22%), Positives = 93/275 (33%), Gaps = 58/275 (21%)

Query: 550 PPKTPVSNVAATSAGPS-------NVGTELNSVPQKSSPFLT--RVPVYPPHSENIQYFQ 600
           PP  P+ + +A SAG +       +  T L +  Q S         PV    S   Q   
Sbjct: 644 PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703

Query: 601 DPRTQIPFEVPQYPQTGYYPPPPTVPAGV------APCVPRFVRSNNVPESSLPPASMPY 654
            P   +P   P        PPPP  P         APC P   + +  P    PP  +  
Sbjct: 704 PPNGVVPPPPP--------PPPPPTPGSAMAQLKPAPCAPSLPQFSAPP----PPLKIHQ 751

Query: 655 ADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRS 714
             H +  +P     + P  PP P P  P  P    +  P   S +   P + Q      +
Sbjct: 752 VQHITQVAPP----TPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPT 807

Query: 715 NSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQ 774
             +PP     +                 +  +  PPS P   VP+P       ++ C   
Sbjct: 808 PPVPPAKKQPA-----------------FPASYIPPSPPTPPVPVPPPTLPKQQSFCA-- 848

Query: 775 IRRKPDQWAQYHTQKAPLVSSTLPVATQSPTPPSP 809
              KP       +  +P+ S    +A+Q P PP+P
Sbjct: 849 ---KPPP-----SPLSPVPSVVKQIASQFPPPPTP 875



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 59/252 (23%), Positives = 80/252 (31%), Gaps = 59/252 (23%)

Query: 550 PPKTPVSNVAATSAGPSNVGTELNSVPQKSSP----------FLTRV-----PVYPPHSE 594
           PP TP S +A     P        S+PQ S+P           +T+V     P  PP   
Sbjct: 717 PPPTPGSAMAQLKPAPC-----APSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA 771

Query: 595 NIQYFQDPRTQIPFEVPQYPQT------GYYPPPPTVPAGVAPCVPRFVR-----SNNVP 643
            +     P+  +    P   +T         PP PT P   A   P F       S   P
Sbjct: 772 PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP 831

Query: 644 ESSLPPASMPYADHYSTFSPRDRMNSSP--------YQPPPP-------QPYGPVPPVPS 688
              +PP ++P    +    P   ++  P          PPPP       QP  PVP   +
Sbjct: 832 PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVA 891

Query: 689 GMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQ 748
               P   ++  W+P        + S   PP     S V+                V   
Sbjct: 892 PQSPPAVKAKPKWQPSSIP----VPSPDFPPPPPESSLVFPPPPPS---------PVPAP 938

Query: 749 PPSEPRTTVPLP 760
           PP  P T  P P
Sbjct: 939 PPPPPPTASPTP 950



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 44/196 (22%), Positives = 62/196 (31%), Gaps = 43/196 (21%)

Query: 637 VRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYD 696
           + S N P +SL P   P     + ++        P  PPPP P  P PP P         
Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP--------- 645

Query: 697 SRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEP--- 753
                 PP         + S  PM V +S++       R  +   +     +PP+ P   
Sbjct: 646 ------PPPLPSQSAPSAGSAAPMFVKYSTI------TRLQNASQHSGALFKPPTPPVMQ 693

Query: 754 -------------RTTVPLPREPCGHLKTSCEEQIRRKP--DQWAQYHTQKAPL----VS 794
                            P P  P      S   Q++  P      Q+     PL    V 
Sbjct: 694 SQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQ 753

Query: 795 STLPVATQSPTPPSPL 810
               VA  +P PP P+
Sbjct: 754 HITQVAPPTPPPPPPI 769



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 58/251 (23%), Positives = 85/251 (33%), Gaps = 62/251 (24%)

Query: 581 PFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGYY----PPPPTVPAGVAP----C 632
           P+ + VP   P  + +  +   +   P   P  P         PPPP +P+  AP     
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSA 660

Query: 633 VPRFVRSNNVPE---------SSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPV 683
            P FV+ + +           +   P + P     S   P+  +  +   PPPP P  P 
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV-KPQILVPPNGVVPPPPPP--PP 717

Query: 684 PPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYY 743
           PP P    A +         P      + + ++ PP   +H   + T +           
Sbjct: 718 PPTPGSAMAQL--------KPAPCAPSLPQFSAPPPPLKIHQVQHITQV----------- 758

Query: 744 SVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTL-PVATQ 802
                PP  P    PLP             Q   KP       T  AP  + T+ PV TQ
Sbjct: 759 -APPTPPPPPPIPAPLP------------PQAPPKP-----LVTIPAPTSTKTVAPVVTQ 800

Query: 803 ----SPTPPSP 809
               +PTPP P
Sbjct: 801 AAPPTPTPPVP 811


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 38/179 (21%), Positives = 66/179 (36%), Gaps = 19/179 (10%)

Query: 620  PPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQP 679
            P  PT P G  P  P+  +  + P+ + P +  PY        P  +  ++    PP  P
Sbjct: 1852 PATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPP 1911

Query: 680  YGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSL 739
                PP+P    A V  + +I R    QR             + H  ++Q  ++ +   +
Sbjct: 1912 QTAQPPLPGPPPAAVEMAMQIQRAAETQR------------QMAHVQIFQRPIQHQMPPM 1959

Query: 740  DGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTLP 798
                 +   PP       P+ R P GHL+        ++   W+Q    +   + S +P
Sbjct: 1960 TPMAPMGMNPP-------PMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQLQSGMP 2011



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 37/131 (28%), Positives = 48/131 (36%), Gaps = 18/131 (13%)

Query: 581 PFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYP-------QTGYYPPPPTVPAGVAPCV 633
           P  T  P + P S   Q  Q P T IP  VP  P           +PPP   P      +
Sbjct: 836 PSRTPTPHHTPPSIGAQ--QPPATTIPAPVPTPPAMPPGPQSQALHPPPRQTPTPPTTQL 893

Query: 634 PRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAP 693
           P+ V      + SLP A  P AD      PR + +++   P P  P  P  P        
Sbjct: 894 PQQV------QPSLPAA--PSADQPQQ-QPRSQQSTAASVPTPTAPLLPPQPATPLSQPA 944

Query: 694 VYDSRRIWRPP 704
           V    ++  PP
Sbjct: 945 VSIEGQVSNPP 955


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 51/171 (29%), Positives = 63/171 (36%), Gaps = 28/171 (16%)

Query: 565 PSNVGTELN------SVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGY 618
           P N GT L       S    SSPF  R P+ P  S  +     P        P   +   
Sbjct: 223 PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAV 282

Query: 619 YPPPPTVPAGVAPCVPRFVRSNNVPESSLPPAS-----MPYADHYSTFSPR---DRMNSS 670
            PPPP       P  PR   S+  P    PP+      +P +   +  +PR     ++ S
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342

Query: 671 PYQPPPPQP--YGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPP 719
              PP P P   GP+PP PS             RPP   RD   RS  LPP
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSE------------RPPPPVRDPPGRSGPLPP 381



 Score = 37.4 bits (85), Expect = 0.076
 Identities = 38/153 (24%), Positives = 52/153 (33%), Gaps = 15/153 (9%)

Query: 548 GSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSP-----------FLTRVPVYPPHSENI 596
           GS  ++P+S+ +  S  P    T   ++  K  P               VP  PP +   
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP 292

Query: 597 QYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPC--VPRFVRSNNVPESSLPPASMPY 654
                PR     + P  P     P PP +P   +     PR  + N    SS PP  +P 
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP--LPS 350

Query: 655 ADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVP 687
                   P       P    PP   GP+PP P
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 44/147 (29%), Positives = 56/147 (38%), Gaps = 33/147 (22%)

Query: 550 PPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFE 609
           PP  PVS   +TS         L + PQ  S    R  V  P S        PR  +P  
Sbjct: 380 PPPPPVSRNGSTSRA-------LPATPQLPS----RSGVDSPRS-------GPRPPLP-- 419

Query: 610 VPQYPQTGYYPPPP---TVPAGV--APCVPRF-VRSNNVPESSLPPASMPYAD---HYST 660
            P  P  G  PPPP   ++  G   +PC   +  R    P S LPP   PY      Y +
Sbjct: 420 -PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPE-PYVQTTKSYPS 477

Query: 661 FSPRDRMNSSPYQPPPPQPYGPVPPVP 687
              R+   S   +     P  P+PP+P
Sbjct: 478 KLARNESRSGSNRRERGAP--PLPPIP 502


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 51/171 (29%), Positives = 63/171 (36%), Gaps = 28/171 (16%)

Query: 565 PSNVGTELN------SVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGY 618
           P N GT L       S    SSPF  R P+ P  S  +     P        P   +   
Sbjct: 223 PGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAV 282

Query: 619 YPPPPTVPAGVAPCVPRFVRSNNVPESSLPPAS-----MPYADHYSTFSPR---DRMNSS 670
            PPPP       P  PR   S+  P    PP+      +P +   +  +PR     ++ S
Sbjct: 283 PPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLS 342

Query: 671 PYQPPPPQP--YGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPP 719
              PP P P   GP+PP PS             RPP   RD   RS  LPP
Sbjct: 343 SSTPPLPSPGRSGPLPPPPSE------------RPPPPVRDPPGRSGPLPP 381



 Score = 37.4 bits (85), Expect = 0.076
 Identities = 38/153 (24%), Positives = 52/153 (33%), Gaps = 15/153 (9%)

Query: 548 GSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSP-----------FLTRVPVYPPHSENI 596
           GS  ++P+S+ +  S  P    T   ++  K  P               VP  PP +   
Sbjct: 233 GSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP 292

Query: 597 QYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPC--VPRFVRSNNVPESSLPPASMPY 654
                PR     + P  P     P PP +P   +     PR  + N    SS PP  +P 
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPP--LPS 350

Query: 655 ADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVP 687
                   P       P    PP   GP+PP P
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPP 383



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 44/147 (29%), Positives = 56/147 (38%), Gaps = 33/147 (22%)

Query: 550 PPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFE 609
           PP  PVS   +TS         L + PQ  S    R  V  P S        PR  +P  
Sbjct: 380 PPPPPVSRNGSTSRA-------LPATPQLPS----RSGVDSPRS-------GPRPPLP-- 419

Query: 610 VPQYPQTGYYPPPP---TVPAGV--APCVPRF-VRSNNVPESSLPPASMPYAD---HYST 660
            P  P  G  PPPP   ++  G   +PC   +  R    P S LPP   PY      Y +
Sbjct: 420 -PDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPE-PYVQTTKSYPS 477

Query: 661 FSPRDRMNSSPYQPPPPQPYGPVPPVP 687
              R+   S   +     P  P+PP+P
Sbjct: 478 KLARNESRSGSNRRERGAP--PLPPIP 502


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 71/293 (24%), Positives = 105/293 (35%), Gaps = 29/293 (9%)

Query: 536 GPSADSVTENKIGSP-PKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSE 594
           G S+DS + N  GS  PK    +  +TS  PS    + N     SS     +   PP  +
Sbjct: 131 GESSDSRSVNDEGSSDPKDIDQDNRSTS--PSIPSPQDNESDSDSSAQQQMLQAQPPALQ 188

Query: 595 NIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPY 654
                    +  P   PQ P  G  P    VP   +P   +   + N P++  P A +P+
Sbjct: 189 APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ---APNQPQA--PTAPVPH 243

Query: 655 ADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPV---------PSGMYAPVYDS-----RRI 700
                  +   +   SP+ PP P P+ P+ P+         PS    P++         +
Sbjct: 244 THIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 303

Query: 701 WRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERY--NSLDGYYSVACQPPSEPRTTVP 758
              P+ Q     +   LPP      +   TS    Y   SL    S +     +P    P
Sbjct: 304 QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP 363

Query: 759 LPREPCG--HLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTLPVATQSPTPPSP 809
           LP  P    H+K      I + P   A  H    P +S   P +  +  PP P
Sbjct: 364 LPPAPLAMPHIKPPPTTPIPQLPAPQAHKH---PPHLSGPSPFSMNANLPPPP 413



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 35/119 (29%), Positives = 46/119 (38%), Gaps = 13/119 (10%)

Query: 535 AGPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSE 594
           +GPS  S+  N    P   P+S+++ T   PS     L  +PQ S P L   P  PP   
Sbjct: 398 SGPSPFSMNANLPPPPALKPLSSLS-THHPPSAHPPPLQLMPQ-SQP-LPSSPAQPPGLT 454

Query: 595 NIQYFQDPRTQIPFEVPQYPQTGYY---PPPPTVPAGVAPCVPRFVRSNNVPESSLPPA 650
             Q    P          +P TG +   P PP       P  P  +     P +S PPA
Sbjct: 455 QSQNLPPPPAS-------HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 506


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 71/293 (24%), Positives = 105/293 (35%), Gaps = 29/293 (9%)

Query: 536 GPSADSVTENKIGSP-PKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSE 594
           G S+DS + N  GS  PK    +  +TS  PS    + N     SS     +   PP  +
Sbjct: 685 GESSDSRSVNDEGSSDPKDIDQDNRSTS--PSIPSPQDNESDSDSSAQQQMLQAQPPALQ 742

Query: 595 NIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPY 654
                    +  P   PQ P  G  P    VP   +P   +   + N P++  P A +P+
Sbjct: 743 APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ---APNQPQA--PTAPVPH 797

Query: 655 ADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPV---------PSGMYAPVYDS-----RRI 700
                  +   +   SP+ PP P P+ P+ P+         PS    P++         +
Sbjct: 798 THIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 857

Query: 701 WRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERY--NSLDGYYSVACQPPSEPRTTVP 758
              P+ Q     +   LPP      +   TS    Y   SL    S +     +P    P
Sbjct: 858 QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP 917

Query: 759 LPREPCG--HLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTLPVATQSPTPPSP 809
           LP  P    H+K      I + P   A  H    P +S   P +  +  PP P
Sbjct: 918 LPPAPLAMPHIKPPPTTPIPQLPAPQAHKH---PPHLSGPSPFSMNANLPPPP 967



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 35/119 (29%), Positives = 46/119 (38%), Gaps = 13/119 (10%)

Query: 535  AGPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSE 594
            +GPS  S+  N    P   P+S+++ T   PS     L  +PQ S P L   P  PP   
Sbjct: 952  SGPSPFSMNANLPPPPALKPLSSLS-THHPPSAHPPPLQLMPQ-SQP-LPSSPAQPPGLT 1008

Query: 595  NIQYFQDPRTQIPFEVPQYPQTGYY---PPPPTVPAGVAPCVPRFVRSNNVPESSLPPA 650
              Q    P          +P TG +   P PP       P  P  +     P +S PPA
Sbjct: 1009 QSQNLPPPPAS-------HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 1060


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 71/293 (24%), Positives = 105/293 (35%), Gaps = 29/293 (9%)

Query: 536 GPSADSVTENKIGSP-PKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSE 594
           G S+DS + N  GS  PK    +  +TS  PS    + N     SS     +   PP  +
Sbjct: 685 GESSDSRSVNDEGSSDPKDIDQDNRSTS--PSIPSPQDNESDSDSSAQQQMLQAQPPALQ 742

Query: 595 NIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPY 654
                    +  P   PQ P  G  P    VP   +P   +   + N P++  P A +P+
Sbjct: 743 APTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ---APNQPQA--PTAPVPH 797

Query: 655 ADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPV---------PSGMYAPVYDS-----RRI 700
                  +   +   SP+ PP P P+ P+ P+         PS    P++         +
Sbjct: 798 THIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSL 857

Query: 701 WRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERY--NSLDGYYSVACQPPSEPRTTVP 758
              P+ Q     +   LPP      +   TS    Y   SL    S +     +P    P
Sbjct: 858 QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQP 917

Query: 759 LPREPCG--HLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTLPVATQSPTPPSP 809
           LP  P    H+K      I + P   A  H    P +S   P +  +  PP P
Sbjct: 918 LPPAPLAMPHIKPPPTTPIPQLPAPQAHKH---PPHLSGPSPFSMNANLPPPP 967



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 35/119 (29%), Positives = 46/119 (38%), Gaps = 13/119 (10%)

Query: 535  AGPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSE 594
            +GPS  S+  N    P   P+S+++ T   PS     L  +PQ S P L   P  PP   
Sbjct: 952  SGPSPFSMNANLPPPPALKPLSSLS-THHPPSAHPPPLQLMPQ-SQP-LPSSPAQPPGLT 1008

Query: 595  NIQYFQDPRTQIPFEVPQYPQTGYY---PPPPTVPAGVAPCVPRFVRSNNVPESSLPPA 650
              Q    P          +P TG +   P PP       P  P  +     P +S PPA
Sbjct: 1009 QSQNLPPPPAS-------HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPA 1060


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 56/197 (28%), Positives = 82/197 (41%), Gaps = 33/197 (16%)

Query: 548 GSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRV-----PVYPPHSENIQYFQDP 602
           G+ P TP  + A  + GP     +  +V  KS+ FL  +     PV    S  +   + P
Sbjct: 491 GTSPPTPTPSTA--TGGPPE---DSPTVAPKSTTFLKNIRQFIMPVVSARSSRV--IKTP 543

Query: 603 RTQIPFEVPQYPQTGYYP---PP----PTVPAGVAPCVPRFVRSNNVPESSLPPASMPYA 655
           R  +  + P+ P+    P   PP    P VP   AP VP   R+   P + +P   +P  
Sbjct: 544 RRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP-VPSPPRAPTPPSTPVP---LPEK 599

Query: 656 DHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSN 715
                  P  R  S   + PPP P  P PP PS   AP   SRR    P+     ++R+ 
Sbjct: 600 RRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRR----PL-----LLRAP 650

Query: 716 SLPPMDVMHSSVYQTSL 732
              P +  H  +Y++ L
Sbjct: 651 QFTPSEA-HLKIYESVL 666



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 50/229 (21%), Positives = 73/229 (31%), Gaps = 53/229 (23%)

Query: 581 PFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSN 640
           P L R P + P   +++ ++   T  P   P+ P+    P PP      A   PR V   
Sbjct: 644 PLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPE----PEPPPADDSPAEPEPRAVGRT 699

Query: 641 N------------------VPESSLPPASMPYADHYSTFSPRDRMNSS--PYQPPPPQPY 680
           N                  V     P  S           P   + +   P   PPPQP 
Sbjct: 700 NHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQ 759

Query: 681 GPVPPVPSGMYAPVYDSR-------------------------RIWRPPMYQRDDIIRSN 715
              PP P  M  P+  +R                         ++++    Q+  +  S 
Sbjct: 760 LQPPPSPQQM-PPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASM 818

Query: 716 SLPP---MDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPR 761
            L P   M+ +  +V Q S R    S D       + PS P + V  PR
Sbjct: 819 PLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPR 867



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 24/86 (27%), Positives = 31/86 (36%), Gaps = 27/86 (31%)

Query: 620 PPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQP 679
           PPPP  P   +P           P    PP++ P                 P  PPPP P
Sbjct: 402 PPPPLTPPAPSP-----------PPPLPPPSTSP---------------PPPLCPPPPPP 435

Query: 680 YGPVPPVPSGMYAPVYDSRRIWRPPM 705
             P PP+PS    P  + +    PP+
Sbjct: 436 VSP-PPLPSPPPPPAQEEQEESPPPV 460



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 49/207 (23%), Positives = 63/207 (30%), Gaps = 26/207 (12%)

Query: 568 VGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPA 627
           V  E+    +K    L   P+ PP               P   P  P     PPPP  P 
Sbjct: 386 VAEEMMPAAEKEEAKLPPPPLTPP--------------APSPPPPLPPPSTSPPPPLCPP 431

Query: 628 GVAPCVPRFVRSNNVP------ESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYG 681
              P  P  + S   P      E S PP             P      +  +     P G
Sbjct: 432 PPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEG 491

Query: 682 PVPPVPSGMYA---PVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNS 738
             PP P+   A   P  DS  +  P        IR   +P +    S V +T  R     
Sbjct: 492 TSPPTPTPSTATGGPPEDSPTV-APKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDED 550

Query: 739 LDGYYSVACQPPSEP--RTTVPLPREP 763
                 V   P   P   T+ P+P+EP
Sbjct: 551 PPKPPKVEVSPVLRPPITTSPPVPQEP 577


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 43/159 (27%), Positives = 61/159 (38%), Gaps = 32/159 (20%)

Query: 550 PPKTPVSNVAATSAGPSNVGTE-LNSVPQKSSPFLTRVP--------------VYPPHSE 594
           PP + ++ ++ TS+  S  G + L S+ +   P    +P              VYPP+  
Sbjct: 424 PPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPP 483

Query: 595 NIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPY 654
                  P +  P  +P  P  GY PPPPT      P  PR   ++ VP    P   +P 
Sbjct: 484 PPPVPPPPASFPPPAIPP-PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPP 542

Query: 655 ADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAP 693
           A +                PPP  P G  PPVP  +  P
Sbjct: 543 ASY----------------PPPAVPPGGQPPVPPPIPPP 565



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 36/119 (30%), Positives = 49/119 (41%), Gaps = 23/119 (19%)

Query: 576 PQKSSP-FLTRVPVYPPHSENIQYFQDPRTQIP-FEVPQYPQTGYYPPPPTVPAGVAPC- 632
           PQ SSP  + R  V  P  EN +  + P  +IP  E    P    +PPP   P   A   
Sbjct: 325 PQPSSPRQVKRAVVVSPKEEN-KAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALG 383

Query: 633 ---VPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPS 688
               P  V + ++P+  +PP + P                +P   PPP P+ P PP PS
Sbjct: 384 EAEPPGPVDATDLPKVQIPPPAHP----------------APVHQPPPLPHRPPPPPPS 426



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 36/175 (20%), Positives = 56/175 (32%), Gaps = 24/175 (13%)

Query: 544 ENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQDPR 603
           ENK   PP   +  +  T           +  P  ++      P  P  + ++   Q P 
Sbjct: 344 ENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPP 403

Query: 604 TQIPFEVPQYPQTGYYPPPPTVPAGVA--------------PCVPRFVRSNNVPESSLPP 649
              P  V Q P   + PPPP   + +                 +   +++      +LPP
Sbjct: 404 PAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP 463

Query: 650 ASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPP 704
           A          + P   +   P+  PP  P  PVPP P+    P         PP
Sbjct: 464 A----------YGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPP 508


>gi|239741653 PREDICTED: hypothetical protein XP_002342271 [Homo
           sapiens]
          Length = 636

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 33/111 (29%), Positives = 48/111 (43%), Gaps = 10/111 (9%)

Query: 588 VYPPHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSL 647
           ++PPH  +   F  PR  +P      P   +YPPPP +    AP  PR    +       
Sbjct: 50  LFPPHPASA--FCPPRLSVPRRRDFLPAAAFYPPPPWL---FAPLPPRLFAPHPASAFCP 104

Query: 648 PPASMPYADHYSTFSPRDR--MNSSPYQPPPPQPY---GPVPPVPSGMYAP 693
           P        H    SPR R  + ++ + PPPP+ +   G +PP P G + P
Sbjct: 105 PRLCCDPPRHRGFMSPRRRGFLPAAGFCPPPPRLFVAAGFLPPRPRGFFPP 155



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 15/77 (19%)

Query: 617 GYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPP 676
           G+ PPPP  P         F R   +P ++   A  P     + F  R  +    + PPP
Sbjct: 418 GFLPPPPPPPR-------LFARLGFLPPAAA--AFCPPPPAAAAFCLRGFLPDPAFSPPP 468

Query: 677 PQPYGP------VPPVP 687
           P+ + P       PPVP
Sbjct: 469 PRLFAPPAPRLFAPPVP 485


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 64/246 (26%), Positives = 84/246 (34%), Gaps = 57/246 (23%)

Query: 471 TTAGNVISVIGSTETTGKIVPST--NG-ISNAENSVSQLISRSTDSTLRALETVKKVGKV 527
           T  G V +   +  +TG    +T  NG I  A +SVS ++  +     R  ET K     
Sbjct: 441 TNLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQ----RHAETSKDKKPA 496

Query: 528 GANGQNAAGPSADSVTENKIGSPPKTPVSNVAATSAGPSNV----GTELNSVPQKSSPFL 583
             N  + A P A    ++ +  PP  PV   + TS  P+      GT    +P     FL
Sbjct: 497 LGNHHDPAVPRAPHAPKSSL--PPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFL 554

Query: 584 TRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVP 643
              P  PP         DP    P      P   + PPPP   AG+A             
Sbjct: 555 PPPPPPPP-------LDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAG------------ 595

Query: 644 ESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRP 703
            S LPP                        PPPP P     PVP     P   ++R   P
Sbjct: 596 -SELPP------------------------PPPPPPAPAPAPVPDSARPPPAVAKRPPVP 630

Query: 704 PMYQRD 709
           P  Q +
Sbjct: 631 PKRQEN 636


>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3
           [Homo sapiens]
          Length = 1585

 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 91/390 (23%), Positives = 137/390 (35%), Gaps = 101/390 (25%)

Query: 572 LNSVPQKSSPFLTRVPVYPPHS--ENIQYFQDPRTQIPFEVPQYPQ----TGYYPPPPTV 625
           +NS PQ  SPF  R  + PP +   N      P  Q P  V Q  Q      + P P  V
Sbjct: 1   MNSQPQTRSPFFQRPQIQPPRATIPNSSPSIRPGAQTPTAVYQANQHIMMVNHLPMPYPV 60

Query: 626 PAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVP- 684
           P G   C+P++  S        PP   P   +             P QPP P P+ P P 
Sbjct: 61  PQGPQYCIPQYRHSG-------PPYVGPPQQY-------------PVQPPGPGPFYPGPG 100

Query: 685 --PVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGY 742
               P+    P Y S+     P+YQ   II      P                       
Sbjct: 101 PGDFPNAYGTPFYPSQ-----PVYQSAPIIVPTQQQP----------------------- 132

Query: 743 YSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTLPVA-- 800
                 PP++        R+P    K   EE +     +            + T P+   
Sbjct: 133 ------PPAKREKKTIRIRDPNQGGKDITEEIMSGGGSR------------NPTPPIGRP 174

Query: 801 TQSPTPPSPLFSVDFRADFSESVSGTKFEEDHLSHYSPWSCGTIGSCINAIDSEPKDVIA 860
           T +PTPP  L S     + S  V GT  E  HL+  +P +  +          +P  V+ 
Sbjct: 175 TSTPTPPQQLPSQ--VPEHSPVVYGT-VESAHLAASTPVTAASDQK--QEEKPKPDPVLK 229

Query: 861 NSNAVLMDLDSGDVKRRVHLFETQRRTKEEDPIIPFSDGPIISKWGAISRSSRTGYHTTD 920
           + + VL  + SG+ K      E + +T E   I+  ++ P+      +S  +R+      
Sbjct: 230 SPSPVLRLVLSGEKK------EQEGQTSETTAIVSIAELPLPPSPTTVSSVARS------ 277

Query: 921 PVQATASQGSATKPISVSDYVPYVNAVDSR 950
            + A  S   +++PI       +  A+D R
Sbjct: 278 TIAAPTSSALSSQPI-------FTTAIDDR 300


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 61/269 (22%), Positives = 99/269 (36%), Gaps = 41/269 (15%)

Query: 575  VPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQY--PQTGYYPPP---------- 622
            VPQ+  P   + P  PP     Q  Q P    P  +PQ   P     PPP          
Sbjct: 753  VPQQPPPPPQQPPPPPPPQ---QQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLE 809

Query: 623  PTVPAGVAPCVPRFVRSN-NVPESSLPP--------ASMPYADHYSTFSPRDRMNSSPYQ 673
            P +P  V   +  F +   ++P+  LPP        ++ P+ + ++  SP    N+ P Q
Sbjct: 810  PQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQ 869

Query: 674  PPPPQPYG----PVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNS---LPPMDVMHSS 726
            P  P        P P  P  +   +  +  + +PPM Q   ++  +     PP+  M   
Sbjct: 870  PSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQ 929

Query: 727  VYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQ------IRRKPD 780
            +Y   L++         SV  Q    P    PLP  P   ++   ++Q       + +P 
Sbjct: 930  LYLQQLQKVQPPTPLLPSVKVQSQPPP----PLPPPPHPSVQQQLQQQPPPPPPPQPQPP 985

Query: 781  QWAQYHTQKAPLVSSTLPVATQSPTPPSP 809
               Q+     P+    +  +T    PP P
Sbjct: 986  PQQQHQPPPRPVHLQPMQFSTHIQQPPPP 1014



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 43/174 (24%), Positives = 63/174 (36%), Gaps = 39/174 (22%)

Query: 545  NKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYP--PHSENIQYFQD- 601
            N +   P  P +  AA    P+         P   SP LT+ P+ P  P ++  Q   + 
Sbjct: 864  NALPQQPSRPSNRAAALPPKPAR--------PPAVSPALTQTPLLPQPPMAQPPQVLLED 915

Query: 602  ------PRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYA 655
                  P T +  ++         PP P +P+         V+  + P   LPP   P  
Sbjct: 916  EEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPS---------VKVQSQPPPPLPPPPHP-- 964

Query: 656  DHYSTFSPRDRMNSSPYQPPPPQPYGP-----VPPVPSGMYAPVYDSRRIWRPP 704
                  S + ++   P  PPPPQP  P      PP       P+  S  I +PP
Sbjct: 965  ------SVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP 1012



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 32/112 (28%), Positives = 38/112 (33%), Gaps = 21/112 (18%)

Query: 572  LNSVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAP 631
            L SV  +S P     P  PPH    Q  Q      P   PQ P    + PPP  P  + P
Sbjct: 945  LPSVKVQSQPPPPLPP--PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR-PVHLQP 1001

Query: 632  C-VPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGP 682
                  ++    P+   PP   P                   QPPPPQP  P
Sbjct: 1002 MQFSTHIQQPPPPQGQQPPHPPP-----------------GQQPPPPQPAKP 1036


>gi|222446607 SH3 domain containing ring finger 2 [Homo sapiens]
          Length = 729

 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 7/69 (10%)

Query: 10 EFLSCPICYNEFDENVHKPISLGCSHTVCKTCLN---KLHRK-ACPFDQTAINTDIDVLP 65
          + L CP+C+ + D        L C HT CK CL    K H++  CP  +T + ++I+ LP
Sbjct: 8  DLLECPVCFEKLDVTAKV---LPCQHTFCKPCLQRVFKAHKELRCPECRTPVFSNIEALP 64

Query: 66 VNFALLQLV 74
           N  L++L+
Sbjct: 65 ANLLLVRLL 73


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 65/278 (23%), Positives = 89/278 (32%), Gaps = 43/278 (15%)

Query: 549  SPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPF 608
            SPP T  S    T + P+   T        S P  T  P+ PP S          T  P 
Sbjct: 1471 SPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPP--TTTPITPPASTT--------TLPPT 1520

Query: 609  EVPQYPQTGYYPPPPTV---PAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRD 665
              P  P T    PPPT    P    P  P          ++LPP + P     +T +P  
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSPPTTTPITPP------TSTTTLPPTTTPSPPPTTTTTPPP 1574

Query: 666  RMNSSPY-----QPP------PPQPYGPVPPV-----PSGMYAPVYDSRRIWRPPMYQRD 709
                SP       PP      PP    P PP      P     P   +     PP     
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT---- 1630

Query: 710  DIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKT 769
                + +LPP          T+      +     +    PP    TT P    P   + T
Sbjct: 1631 ---STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITT 1687

Query: 770  SCEEQIRRKPDQWAQYHTQKAPLVSSTLPVATQSPTPP 807
            +            +   T  +P+ ++T P +T +P+PP
Sbjct: 1688 TPSPPTTTMTTP-SPTTTPSSPITTTTTPSSTTTPSPP 1724



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 62/272 (22%), Positives = 88/272 (32%), Gaps = 46/272 (16%)

Query: 550  PPKTPVSNVAATSA-----GPSNVGTELNSVPQKSSPFL-TRVPVYPPHSENIQYFQDPR 603
            P  TP++  A+T+       PS   T   + P  ++P   T  P+ PP S          
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT-------- 1554

Query: 604  TQIPFEVPQYPQTGYYPPPPTV----PAGVAPCVPRFVRSNNVPESSLPPASMPYADHYS 659
            T  P   P  P T    PPPT     P    P  P       +  ++ PP + P     +
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP------TITTTTPPPTTTPSPPTTT 1608

Query: 660  TFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPP 719
            T +P       P   P P    P+ P  S    P   +     PP         +   PP
Sbjct: 1609 TTTP------PPTTTPSPPTTTPITPPTSTTTLPPTTTPS--PPPTTTTTPPPTTTPSPP 1660

Query: 720  MDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPRE---PCGHLKTSCEEQIR 776
                 S    T+      +     S     PS P TT+  P     P   + T+      
Sbjct: 1661 TTTTPSPPITTTTTPPPTTTPS--SPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSST 1718

Query: 777  RKPDQWAQYHTQKAPLVSSTLPVATQSPTPPS 808
              P           P  + T P  T +P+PP+
Sbjct: 1719 TTPSP---------PPTTMTTPSPTTTPSPPT 1741



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 62/267 (23%), Positives = 83/267 (31%), Gaps = 19/267 (7%)

Query: 549  SPPKTPVSNVAATSAGPSNVGTELNSVPQKS--SPFLTRVPVYPPHSENIQYFQDPRTQI 606
            SPP T  + +  T+  PS   T   + P  +  SP +T     PP +          T  
Sbjct: 1407 SPPPTSTTTLPPTTT-PSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465

Query: 607  PFEVPQYPQTGYYPP-----PPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTF 661
            P   P  P T   PP     PPT      P  P    S        PPAS       +T 
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPP--PTTTPSPPTTTPITPPASTTTLPPTTTP 1523

Query: 662  SPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMD 721
            SP     ++P     P P    P  P      +  +     PP         +   PP  
Sbjct: 1524 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT 1583

Query: 722  VMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPDQ 781
               S    T+      +     +     P  P TT P P  P     T         P  
Sbjct: 1584 TTPSPPTITTTTPPPTTTPSPPTTTTTTP--PPTTTPSP--PTTTPITPPTSTTTLPPTT 1639

Query: 782  WAQYHTQKAPLVSSTLPVATQSPTPPS 808
                 T   P  ++T P  T +P+PP+
Sbjct: 1640 -----TPSPPPTTTTTPPPTTTPSPPT 1661



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 29/121 (23%), Positives = 39/121 (32%), Gaps = 22/121 (18%)

Query: 542  VTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFL-------TRVPVYPPHSE 594
            +T      P  TP S +  T + P+   T  +     SSP         T  P  PP + 
Sbjct: 1669 ITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTM 1728

Query: 595  NIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPY 654
                     T  P   P  P T     PPT  +      P       +P S  PP   P+
Sbjct: 1729 T--------TPSPTTTPSPPTTTMTTLPPTTTSSPLTTTP-------LPPSITPPTFSPF 1773

Query: 655  A 655
            +
Sbjct: 1774 S 1774


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 45/162 (27%), Positives = 54/162 (33%), Gaps = 38/162 (23%)

Query: 531 GQNAAGPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYP 590
           G   AGP   SV      SP   P +    +  GP        + P    P +   P  P
Sbjct: 283 GSGLAGPKRSSVV-----SPSHPPPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPP 337

Query: 591 PHSENIQYFQDPRTQIPFEVPQYPQTGYY---PPPPTVPAGVAPCVPRFVRSNNVPESSL 647
           P       F  P T  P   P +P    +   PPPP  PA   P +P             
Sbjct: 338 PVG-----FGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLPP------------ 380

Query: 648 PPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSG 689
           PP S P                +P  PPPP P GP PP  +G
Sbjct: 381 PPLSQP-------------TGGAPPPPPPPPPPGPPPPPFTG 409



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 28/79 (35%), Positives = 32/79 (40%), Gaps = 10/79 (12%)

Query: 619 YPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFS----PRDRMNSSPYQP 674
           YPPPP   +  +P  P F   N  P    PPA   Y       S    P+     SP  P
Sbjct: 246 YPPPPQSDSASSPS-PSFSEDNLPP----PPAEFSYPVDNQRGSGLAGPKRSSVVSPSHP 300

Query: 675 PPPQPYGPVPPVPSGMYAP 693
           PP  P G  PP P   +AP
Sbjct: 301 PPAPPLGS-PPGPKPGFAP 318


>gi|153791514 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 10 EFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKA-----CPF-DQTAINTDIDV 63
          E L CPIC   F E   +P  L C HT+C+ CL KL   +     CPF  +    T +  
Sbjct: 16 EVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRITSLTQ 75

Query: 64 LPVNFALLQLV 74
          L  N  +L+++
Sbjct: 76 LTDNLTVLKII 86


>gi|153792582 tripartite motif-containing 32 [Homo sapiens]
          Length = 653

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 25/71 (35%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 10 EFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKA-----CPF-DQTAINTDIDV 63
          E L CPIC   F E   +P  L C HT+C+ CL KL   +     CPF  +    T +  
Sbjct: 16 EVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRITSLTQ 75

Query: 64 LPVNFALLQLV 74
          L  N  +L+++
Sbjct: 76 LTDNLTVLKII 86


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 45/186 (24%), Positives = 78/186 (41%), Gaps = 15/186 (8%)

Query: 468  TVTTTAGNVISVIGSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKV 527
            T T      +   GST T   I P+T+G S A +S S   +  T ++L +  +       
Sbjct: 1481 TGTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFS---TNKTPTSLHSHTS------- 1530

Query: 528  GANGQNAAGPSADSVTENKIGSPPKTPVSNV-AATSAGPSNVGTELNSVPQKSSPFLTRV 586
              +       S  ++T N   +  +TPV++  +ATS+ P    T  +S P  SSPF +  
Sbjct: 1531 STHHPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFT-THSPPTGSSPFSSTG 1589

Query: 587  PVYPPHSENIQYF---QDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVP 643
            P+     +    +     P+T +P  VP +  +   P   TV       +      +++P
Sbjct: 1590 PMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMP 1649

Query: 644  ESSLPP 649
              ++PP
Sbjct: 1650 TGTIPP 1655



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 40/185 (21%), Positives = 69/185 (37%), Gaps = 13/185 (7%)

Query: 468  TVTTTAGNVISVIGSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKV 527
            T T      I   GST T   + P+T+G S + +S     S +  ST     T       
Sbjct: 1874 TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSS----FSTAKTSTSLPYHT------S 1923

Query: 528  GANGQNAAGPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVP 587
              +       S  ++T     +  +TPV++  + S+         +S P  SSPF +  P
Sbjct: 1924 STHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGP 1983

Query: 588  VYPPHSENIQYF---QDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPE 644
            +     +    +     P+T +P  VP +  +   P   TV       +      ++ P 
Sbjct: 1984 MTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPT 2043

Query: 645  SSLPP 649
             ++PP
Sbjct: 2044 GTVPP 2048



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 61/314 (19%), Positives = 113/314 (35%), Gaps = 39/314 (12%)

Query: 470  TTTAGNVISVIGSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGA 529
            T+T+   I+   ++  T  +  +T+G S + +S S   +  T ++L +  +         
Sbjct: 1707 TSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFS---TAKTSTSLHSHTS-------ST 1756

Query: 530  NGQNAAGPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVY 589
            +       S  S+T N   +  +TPV++  + ++         +S P  ++P  +  PV 
Sbjct: 1757 HHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVT 1816

Query: 590  PPHSENIQYF---QDPRTQIPFEVPQYPQTGYYPPPPTV-----------------PAGV 629
                +    +     P T +P  VP +  +   P   TV                 P G 
Sbjct: 1817 ATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGT 1876

Query: 630  APCVPRFVRSNNVPESSLP--PASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVP 687
             P  P  +++     ++ P  P +   +   S+FS      S PY       +  V P  
Sbjct: 1877 IP-PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTH-HPEVTPTS 1934

Query: 688  SGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSL--DGYYSV 745
            +    P + S     P  +       S+ LP     HS    +S       +    + + 
Sbjct: 1935 TTNITPKHTSTGTRTPVAHTTS--ASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQTT 1992

Query: 746  ACQP-PSEPRTTVP 758
               P PS P+TT+P
Sbjct: 1993 TTYPTPSHPQTTLP 2006



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 79/373 (21%), Positives = 119/373 (31%), Gaps = 52/373 (13%)

Query: 468  TVTTTAGNVISVIGSTETTGKIVPSTNGISNAENSV-----SQLISRSTDSTLRALETVK 522
            T T      +   GST T   +  +T+G S A +S+     S  +   T ST  A  T  
Sbjct: 1650 TGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATST 1709

Query: 523  KVGKVGANGQNAAGPSADSVT-----ENKIGSPPKTPVSNVAATSA--GPSNVGTELNSV 575
                +  N  +   P     T          S  KT  S  + TS+   P    T   S+
Sbjct: 1710 STTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSI 1769

Query: 576  PQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPR 635
                +   TR PV    S         R   PF     P TG  P   T P         
Sbjct: 1770 TPNHTSTGTRTPVAHTTSAT-----SSRLPTPF-TTHSPPTGTTPISSTGPV----TATS 1819

Query: 636  FVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGM--YAP 693
            F  +   P  S P  ++P   H  +FS              P  +  + P  + M   A 
Sbjct: 1820 FQTTTTYPTPSHPHTTLP--THVPSFST---------SLVTPSTHTVIIPTHTQMATSAS 1868

Query: 694  VYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQT----SLRERYNSLDGYYSVACQP 749
            ++       PP         +++ PPM    S   Q+    S  +   SL  + S    P
Sbjct: 1869 IHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHP 1928

Query: 750  PSEPRTTVPL--------PREPCGHLKTSCEEQI-----RRKPDQWAQYHTQKAPLVSST 796
               P +T  +         R P  H  ++   ++        P   +   +   P+ +++
Sbjct: 1929 EVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATS 1988

Query: 797  LPVATQSPTPPSP 809
                T  PTP  P
Sbjct: 1989 FQTTTTYPTPSHP 2001



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 43/206 (20%), Positives = 74/206 (35%), Gaps = 17/206 (8%)

Query: 452  ATVR---TFPLLNKVGVNNTVTTTAGNVISVIGSTETTGKIVPS--TNGIS-NAENSVSQ 505
            AT+R   T P + +     T +T +    S   ST  T   +P+  T+G S     S +Q
Sbjct: 1290 ATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPATSGTSPTLPKSTNQ 1349

Query: 506  LI--SRSTDSTLRALETVKKVGKVGANGQNAAGPSADSVTENKIGSPPKTPVSNVAATSA 563
             +  + +T +T          G           P+A   T+ +  +   TP      T+ 
Sbjct: 1350 ELPGTTATQTTGPRPTPASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTP--QTPHTTH 1407

Query: 564  GPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPP 623
             P   G+ + S    ++        YP  S        P T +P  VP +  +   P   
Sbjct: 1408 SPPTAGSPVPSTGPVTATSFHATTTYPTPSH-------PETTLPTHVPPFSTSLVTPSTH 1460

Query: 624  TVPAGVAPCVPRFVRSNNVPESSLPP 649
            TV       +     +++ P  ++PP
Sbjct: 1461 TVITPTHAQMATSASNHSAPTGTIPP 1486


>gi|229892345 GLI family zinc finger 1 isoform 2 [Homo sapiens]
          Length = 978

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 46/163 (28%), Positives = 61/163 (37%), Gaps = 28/163 (17%)

Query: 536 GPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSS----------PFLTR 585
           GP   +        P   P+     T+ GP       N  PQ++S           F + 
Sbjct: 606 GPEGAAAEPYGARGPGSLPLGPGPPTNYGP-------NPCPQQASYPDPTQETWGEFPSH 658

Query: 586 VPVYP-PHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPE 644
             +YP P +    Y Q PR +   +V   P+ G   P  +   G+APC+       N   
Sbjct: 659 SGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGC--PVGSDSTGLAPCL-------NAHP 709

Query: 645 SSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVP 687
           S  PP   P   HY   SP   + S PY  PPP  Y P  P P
Sbjct: 710 SEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPD-YLPSEPRP 751



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 23/90 (25%), Positives = 31/90 (34%), Gaps = 11/90 (12%)

Query: 611 PQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSS 670
           P  P + Y P PP++    A           V  S +     PY D    F P D +   
Sbjct: 550 PYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMD----FPPTDTLGYG 605

Query: 671 PYQPPPPQPYG-------PVPPVPSGMYAP 693
             +    +PYG       P+ P P   Y P
Sbjct: 606 GPEGAAAEPYGARGPGSLPLGPGPPTNYGP 635


>gi|4885279 GLI family zinc finger 1 isoform 1 [Homo sapiens]
          Length = 1106

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 46/163 (28%), Positives = 61/163 (37%), Gaps = 28/163 (17%)

Query: 536 GPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSS----------PFLTR 585
           GP   +        P   P+     T+ GP       N  PQ++S           F + 
Sbjct: 734 GPEGAAAEPYGARGPGSLPLGPGPPTNYGP-------NPCPQQASYPDPTQETWGEFPSH 786

Query: 586 VPVYP-PHSENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPE 644
             +YP P +    Y Q PR +   +V   P+ G   P  +   G+APC+       N   
Sbjct: 787 SGLYPGPKALGGTYSQCPRLEHYGQVQVKPEQGC--PVGSDSTGLAPCL-------NAHP 837

Query: 645 SSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVP 687
           S  PP   P   HY   SP   + S PY  PPP  Y P  P P
Sbjct: 838 SEGPPHPQPLFSHYPQPSPPQYLQSGPYTQPPPD-YLPSEPRP 879



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 23/90 (25%), Positives = 31/90 (34%), Gaps = 11/90 (12%)

Query: 611 PQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSS 670
           P  P + Y P PP++    A           V  S +     PY D    F P D +   
Sbjct: 678 PYLPTSVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMD----FPPTDTLGYG 733

Query: 671 PYQPPPPQPYG-------PVPPVPSGMYAP 693
             +    +PYG       P+ P P   Y P
Sbjct: 734 GPEGAAAEPYGARGPGSLPLGPGPPTNYGP 763


>gi|27436877 tripartite motif-containing 59 [Homo sapiens]
          Length = 403

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 22/93 (23%)

Query: 10 EFLSCPICYNEFDENVHKPISLGCSHTVCKTCLNKLHRKA--------------CPFDQT 55
          E L+CPICY+ F++    P  L CSHT C+ CL  + + +              CP  ++
Sbjct: 6  EELTCPICYSIFED----PRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRS 61

Query: 56 AIN---TDIDVLPVNFALLQLVGA-QVPDHQSI 84
                T I+ LPVNFAL  ++   Q  DH  I
Sbjct: 62 ITEIAPTGIESLPVNFALRAIIEKYQQEDHPDI 94


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 67/281 (23%), Positives = 90/281 (32%), Gaps = 45/281 (16%)

Query: 548 GSPPKTPVSNVAATSAGP--------SNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYF 599
           G P    V+++     GP           G +L   PQ  +P    +P+ PP  E+    
Sbjct: 394 GQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLE--PQLEAPLNEEMPLLPPPEES---- 447

Query: 600 QDPRTQIPFEVPQYPQ---TGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYA- 655
             P +  P E P  P    +   PPP  +PA   P      R       S PP   P + 
Sbjct: 448 --PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505

Query: 656 -DHYSTFSPRDRMNSSPYQPPPPQPYGPV------PPVPSGMYAPVYDSRRIWRPPMYQR 708
               S FSP   +  SP  PP   P  P       PP  +   +P ++   +  PP    
Sbjct: 506 PPESSPFSP---LEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP---- 558

Query: 709 DDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLK 768
                   LP      +S       E   S     S    PP   R   P    P   L 
Sbjct: 559 ------EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP---LS 609

Query: 769 TSCEEQIRRKPDQWAQYHTQKAPLVSSTLPVATQSPTPPSP 809
              EE     P + ++      P  S   P   +SP  P P
Sbjct: 610 PPPEESPLSPPPEASR--LSPPPEDSPMSPPPEESPMSPPP 648



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 65/242 (26%), Positives = 81/242 (33%), Gaps = 40/242 (16%)

Query: 574 SVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIPFEVPQYP--QTGYYPPPPTVPAGVAP 631
           S P + SP        PP S      ++     P E P  P  +T   PPP       +P
Sbjct: 495 SPPPEESPLSP-----PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA-----SP 544

Query: 632 CVPRFVRSN-NVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGM 690
             P F  S  + P   LP +  P A   S  SP      SP  PPP +     PP  S +
Sbjct: 545 LSPPFEESPLSPPPEELPTSPPPEA---SRLSPPPE--ESPMSPPPEESPMSPPPEASRL 599

Query: 691 YAPVYDSRRIWRP---PMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVAC 747
           + P  +S     P   P+    +  R  S PP D   S   + S                
Sbjct: 600 FPPFEESPLSPPPEESPLSPPPEASRL-SPPPEDSPMSPPPEES--------------PM 644

Query: 748 QPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTLPVATQSPTPP 807
            PP E     PLP      L    EE     P +  +  T   P  S   P    SPT P
Sbjct: 645 SPPPEVSRLSPLP--VVSRLSPPPEESPLSPPPE--ESPTSPPPEASRLSPPPEDSPTSP 700

Query: 808 SP 809
            P
Sbjct: 701 PP 702



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 68/289 (23%), Positives = 96/289 (33%), Gaps = 72/289 (24%)

Query: 546  KIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQ 605
            ++  PP +P         G      EL   P    P L+ +   P  SE     + P + 
Sbjct: 854  ELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP---GEPPLSP 910

Query: 606  IPFEVPQYPQ-----------TGYYPPP--PTVPAGVAPCV--------PRFVRSNNVPE 644
            +P E+P  P                PPP  P + A   P +        P   + ++ PE
Sbjct: 911  LPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPE 970

Query: 645  SSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPP 704
            S   P + P  +  +  SP    N +  +P PP    P P  P G  +P           
Sbjct: 971  S---PLAAPILE--TPISPPPEANCTDPEPVPPMILPPSPGSPVGPASP----------- 1014

Query: 705  MYQRDDIIRSNSLPPMD---VMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPR 761
                   I    LPP     + HS V Q S   +           C PP+ P  +VP P 
Sbjct: 1015 -------ILMEPLPPQCSPLLQHSLVPQNSPPSQ-----------CSPPALP-LSVPSPL 1055

Query: 762  EPCGHLKTSCEEQIRRKPDQWAQYHTQKAPLVSS-TLPVATQSPTPPSP 809
             P G +    +E         A+ H  +   VS    P    S T P P
Sbjct: 1056 SPIGKVVGVSDE---------AELHEMETEKVSEPECPALEPSATSPLP 1095



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 73/333 (21%), Positives = 109/333 (32%), Gaps = 55/333 (16%)

Query: 535 AGPSADSVTENKIGSPPKT-PVSNVA-ATSAGPSNVGTELNSVPQKS--SPFLTRVPVYP 590
           A P +    E+ +  PP+  P S    A+   P    + ++  P++S  SP      ++P
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFP 601

Query: 591 PHSENIQYFQDPRTQIPFEVPQYP------------QTGYYPPPPTVPAGVAPCVPRFVR 638
           P  E+      P +  P E P  P             +   PPP   P    P V R   
Sbjct: 602 PFEES------PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655

Query: 639 SNNVPESSLPPASMPYAD--HYSTFSPRDRMN-------SSPYQPPPPQPYGPVPPVPSG 689
              V   S PP   P +     S  SP    +        SP  PPP       PP  S 
Sbjct: 656 LPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSL 715

Query: 690 MYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLRERYNSLDGYYSVACQP 749
           M  P+ +S  +   P+ +   +   +  P +       + +   E  +           P
Sbjct: 716 MSLPLEESPLL---PLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPH---------LSP 763

Query: 750 PSEPRTTVPLPREPC-------GHLKTSCE-EQIRRKPDQWAQYHTQKAPLVSSTLPVAT 801
            +E     P P EPC        HL    E   +  +P++       + P +S       
Sbjct: 764 QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC 823

Query: 802 QSPTPPSPLFSVDFRADFSESVSGTKFEEDHLS 834
            SP P     S        E     + EE HLS
Sbjct: 824 LSPQPEESHLS----PQSEEPCLSPRPEESHLS 852



 Score = 30.4 bits (67), Expect = 9.3
 Identities = 41/190 (21%), Positives = 63/190 (33%), Gaps = 35/190 (18%)

Query: 590  PPHSENIQYFQDPRTQIPFEVPQY--PQTGYYPPPP--TVPAGVAPCVPRFVRSNNVPES 645
            PP  E+ +  +  + ++    P Y  P  G+   P   T   G+    P   ++   P +
Sbjct: 2276 PPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA 2335

Query: 646  SLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPM 705
            S      P             +   P +PPP Q   P PP    ++ P   +    +PP+
Sbjct: 2336 SQVEPQSP------------GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383

Query: 706  YQRDD--------IIRSNSLP-------PMDVMHSSVYQTSLRERYNSLDGYYSVACQPP 750
              R           +   SLP       P      S  Q+ L  R  S + +    C  P
Sbjct: 2384 TPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAF----CPSP 2439

Query: 751  SEPRTTVPLP 760
              PR   P P
Sbjct: 2440 VTPRFQSPDP 2449


>gi|209862787 hypothetical protein LOC100191040 [Homo sapiens]
          Length = 353

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 43/171 (25%), Positives = 59/171 (34%), Gaps = 10/171 (5%)

Query: 602 PRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPES-SLPPASMPYADHYST 660
           P    P  +PQ+    + PP    P G  P   R V    +P + SLP  +      +  
Sbjct: 40  PNVLTPDRIPQF----FIPPRLPDPGGAVPAARRHVAGRGLPATCSLPHLAGREGWAFLP 95

Query: 661 FSPRDRMNSSPYQPPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPM 720
            SP  R   S +  PPP P G +P   S ++    D R    P      D   S    P 
Sbjct: 96  ESPHTRRRESLFHGPPPAPAGGLPAAQSRLHVSAPDLRLCRAPD----SDTASSPDSSPF 151

Query: 721 DVMHSSVYQTSLRERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSC 771
                 + +  +   ++      S A   P  PR   P P  P  HL   C
Sbjct: 152 GSPRPGLGRRRVSRPHSLSPEKASSADTSPHSPRRAGP-PTPPLFHLDFLC 201


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 26/81 (32%), Positives = 32/81 (39%), Gaps = 14/81 (17%)

Query: 614 PQTGYYPPPPTVPAGV-----APCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMN 668
           P     PPPP +P+G+     AP +P       +P    PP  +P         P     
Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLP---------PPSSAG 697

Query: 669 SSPYQPPPPQPYGPVPPVPSG 689
             P  PPPP P  P PP P G
Sbjct: 698 PPPPPPPPPLPNSPAPPNPGG 718



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 19/50 (38%), Positives = 27/50 (54%), Gaps = 4/50 (8%)

Query: 645 SSLPPASMP--YADHYSTFSPRDRMNSSPYQ--PPPPQPYGPVPPVPSGM 690
           SSL   S P  + D ++   P + M S+  +  PPPP    P PP+PSG+
Sbjct: 613 SSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGL 662


>gi|221139926 NHS-like 1 [Homo sapiens]
          Length = 1606

 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 91/358 (25%), Positives = 139/358 (38%), Gaps = 71/358 (19%)

Query: 474  GNVISVIGSTETTGKIVPSTNGISNAENSVSQLISRSTDSTLRALETVKKVGKVGANGQN 533
            G+V   I S E + +++  ++G S+  N+ + L              +K V    ANG+ 
Sbjct: 830  GSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPV--------FLKSVSP--ANGKG 879

Query: 534  AAGPSADSVTENKIGSPPKTPVSNVAATSAGPSNVGTELNSVPQKSSPFLTRVPVYPPHS 593
               P       + I S     VS  +++++  S+  TE +   +K  P +   P  PP  
Sbjct: 880  KPKPKVPERKSSLISS-----VSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPAPPPPP 934

Query: 594  ENIQYFQDPRTQIPFEVPQYPQTG-----------YYPPPPTVPAGVAP-------CV-- 633
                 F  P  + PF  P  P T             +PPPP  P  + P       C+  
Sbjct: 935  VPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPP--PEALIPFCSPPDWCLSP 992

Query: 634  PRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQPPPPQPYGPV------PPVP 687
            PR   S  +P+S   P S+P         P   + SS  +PPP  P  P       PP  
Sbjct: 993  PRPALSPILPDS---PVSLPL--------PPPLLPSS--EPPPAPPLDPKFMKDTRPPFT 1039

Query: 688  SGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQ-TSLRE-RYNSLDGYYSV 745
            +        SR   RPP  + +      S PPM ++ +   Q   LR  R NS      +
Sbjct: 1040 NS--GQPESSRGSLRPPSTKEE-----TSRPPMPLITTEALQMVQLRPVRKNSGAEAAQL 1092

Query: 746  ACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPDQWAQYHTQKAPLVSSTLPVATQS 803
            + +   E RT    P  P  HLK S   + R   ++  +  +Q A  V+S+LP   +S
Sbjct: 1093 SERTAQEQRT----PVAPQYHLKPSAFLKSRNSTNE-MESESQPAS-VTSSLPTPAKS 1144



 Score = 37.4 bits (85), Expect = 0.076
 Identities = 53/210 (25%), Positives = 67/210 (31%), Gaps = 43/210 (20%)

Query: 614  PQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMPYADHYSTFSPRDRMNSSPYQ 673
            P  G   P P VP   +      + S ++  SS   +S    +   T    D    SP  
Sbjct: 874  PANGKGKPKPKVPERKSS----LISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPPA 929

Query: 674  PPPPQPYGPVPPVPSGMYAPVYDSRRIWRPPMYQRDDIIRSNSLPPMDVMHSSVYQTSLR 733
            PPP       PPVPS  + P    R  + PP     D  + + LP     HS V+     
Sbjct: 930  PPP-------PPVPSPPF-PCPADRSPFLPPPPPVTDCSQGSPLP-----HSPVF----- 971

Query: 734  ERYNSLDGYYSVACQPPSEPRTTVPLPREPCGHLKTSCEEQIRRKPDQWAQYHTQKAPLV 793
                           PP  P   +P    P   L           PD          PL 
Sbjct: 972  ---------------PPPPPEALIPFCSPPDWCLSPPRPALSPILPDS-----PVSLPLP 1011

Query: 794  SSTLPVATQSPTPP-SPLFSVDFRADFSES 822
               LP +   P PP  P F  D R  F+ S
Sbjct: 1012 PPLLPSSEPPPAPPLDPKFMKDTRPPFTNS 1041


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 50/166 (30%), Positives = 61/166 (36%), Gaps = 29/166 (17%)

Query: 550 PPKTPVSNVAATSAGP--SNVGTELNSVPQKSSPFLTRVPVYPPHSENIQYFQDPRTQIP 607
           PP  PV    +  A P  S   T  +  P   +    +VP  PP S  +     P  Q P
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502

Query: 608 FEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLP--PASMPYADHYSTFSPRD 665
             +   P     PPP   PA   P           P  +LP  PAS P     + FSP  
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATP-----------PLQALPSPPASFP---GQAPFSPSA 548

Query: 666 RMNSSPYQPPPPQ-------PYGPVPPVPSGMYAPVYDSRRIWRPP 704
            +  SP   PPPQ       P   VPP P    +P   + R  RPP
Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPA--SPTLQAPR--RPP 590



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 48/161 (29%), Positives = 64/161 (39%), Gaps = 24/161 (14%)

Query: 549 SPPKTPVSNVAATSAG-----------PSNVGTELNSVPQKSSPFLT----RVPVYPPHS 593
           SPP TP S  A TS G           PS   + L + P ++ P L     + P  PP S
Sbjct: 356 SPPATPPSQ-ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414

Query: 594 ENIQYFQDPRTQIPFEVPQYPQTGYYPPPPTVPAGVAPCVPRFVRSNNVPESSLPPASMP 653
             +     P  Q P  +  +     + PPP+ P   AP  P    S  V  S+ PP+  P
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV-QAPFSP--PASPPVSPSATPPSQAP 471

Query: 654 YADHYSTFSPRDRMNSSPYQPPPPQPYG-PVPPVPSGMYAP 693
                S  +P  ++  SP   PP  P   P P  P  + AP
Sbjct: 472 ----PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,792,276
Number of Sequences: 37866
Number of extensions: 2301986
Number of successful extensions: 15314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 73
Number of HSP's successfully gapped in prelim test: 651
Number of HSP's that attempted gapping in prelim test: 11575
Number of HSP's gapped (non-prelim): 2847
length of query: 1064
length of database: 18,247,518
effective HSP length: 113
effective length of query: 951
effective length of database: 13,968,660
effective search space: 13284195660
effective search space used: 13284195660
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.