Search of human proteins with 154350241

Search of human proteins with 154350241

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange
protein 3 [Homo sapiens]
         (2177 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange p...  4335   0.0  
gi|51479145 brefeldin A-inhibited guanine nucleotide-exchange pr...    99   3e-20
gi|150417986 ADP-ribosylation factor guanine nucleotide-exchange...    92   7e-18
gi|114326552 MON2 homolog [Homo sapiens]                               49   4e-05
gi|195927059 axin 2 [Homo sapiens]                                     34   1.8  
gi|63055059 SH3 and PX domains 2B [Homo sapiens]                       34   1.8  
gi|239757530 PREDICTED: hypothetical protein [Homo sapiens]            33   3.1  
gi|239752052 PREDICTED: hypothetical protein [Homo sapiens]            33   3.1  
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]          33   3.1  
gi|55749621 pleckstrin homology domain containing, family G, mem...    33   3.1  
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ...    33   4.0  
gi|24497533 homeobox C10 [Homo sapiens]                                33   4.0  
gi|221316754 exophilin 5 isoform c [Homo sapiens]                      32   5.2  
gi|221316751 exophilin 5 isoform b [Homo sapiens]                      32   5.2  
gi|16753205 ubiquilin 1 isoform 2 [Homo sapiens]                       32   5.2  
gi|16753203 ubiquilin 1 isoform 1 [Homo sapiens]                       32   5.2  
gi|19924103 synapsin II isoform IIa [Homo sapiens]                     32   5.2  
gi|221316747 exophilin 5 isoform a [Homo sapiens]                      32   5.2  
gi|19924101 synapsin II isoform IIb [Homo sapiens]                     32   5.2  
gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]        32   6.8  
gi|38045915 pregnancy-associated plasma protein A preproprotein ...    32   6.8  
gi|7019477 HtrA serine peptidase 2 isoform 1 preproprotein [Homo...    32   6.8  
gi|221316659 leupaxin isoform 1 [Homo sapiens]                         32   6.8  
gi|4758670 leupaxin isoform 2 [Homo sapiens]                           32   6.8  
gi|53729363 leucine rich repeat and sterile alpha motif containi...    32   6.8  
gi|53729361 leucine rich repeat and sterile alpha motif containi...    32   6.8  
gi|53729359 leucine rich repeat and sterile alpha motif containi...    32   6.8  
gi|34335253 disks large-associated protein 4 isoform a [Homo sap...    32   8.9  
gi|63054864 phosphoprotein associated with glycosphingolipid mic...    32   8.9  
gi|157388902 semaphorin 4C [Homo sapiens]                              32   8.9  

>gi|154350241 brefeldin A-inhibited guanine nucleotide-exchange
            protein 3 [Homo sapiens]
          Length = 2177

 Score = 4335 bits (11244), Expect = 0.0
 Identities = 2177/2177 (100%), Positives = 2177/2177 (100%)

Query: 1    MEEILRKLQKEASGSKYKAIKESCTWALETLGGLDTIVKIPPHVLREKCLLPLQLALESK 60
            MEEILRKLQKEASGSKYKAIKESCTWALETLGGLDTIVKIPPHVLREKCLLPLQLALESK
Sbjct: 1    MEEILRKLQKEASGSKYKAIKESCTWALETLGGLDTIVKIPPHVLREKCLLPLQLALESK 60

Query: 61   NVKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNAVKVTPSLNEDLQVEVMKVLL 120
            NVKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNAVKVTPSLNEDLQVEVMKVLL
Sbjct: 61   NVKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNAVKVTPSLNEDLQVEVMKVLL 120

Query: 121  CITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSDLTLQLRQRQEN 180
            CITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSDLTLQLRQRQEN
Sbjct: 121  CITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSDLTLQLRQRQEN 180

Query: 181  TIIENPDVPQDFGNQGSTVESLCDDVVSVLTVLCEKLQAAINDSQQLQLLYLECILSVLS 240
            TIIENPDVPQDFGNQGSTVESLCDDVVSVLTVLCEKLQAAINDSQQLQLLYLECILSVLS
Sbjct: 181  TIIENPDVPQDFGNQGSTVESLCDDVVSVLTVLCEKLQAAINDSQQLQLLYLECILSVLS 240

Query: 241  SSSSSMHLHRRFTDLIWKNLCPALIVILGNPIHDKTITSAHTSSTSTSLESDSASPGVSD 300
            SSSSSMHLHRRFTDLIWKNLCPALIVILGNPIHDKTITSAHTSSTSTSLESDSASPGVSD
Sbjct: 241  SSSSSMHLHRRFTDLIWKNLCPALIVILGNPIHDKTITSAHTSSTSTSLESDSASPGVSD 300

Query: 301  HGRGSGCSCTAPALSGPVARTIYYIAAELVRLVGSVDSMKPVLQSLYHRVLLYPPPQHRV 360
            HGRGSGCSCTAPALSGPVARTIYYIAAELVRLVGSVDSMKPVLQSLYHRVLLYPPPQHRV
Sbjct: 301  HGRGSGCSCTAPALSGPVARTIYYIAAELVRLVGSVDSMKPVLQSLYHRVLLYPPPQHRV 360

Query: 361  EAIKIMKEILGSPQRLCDLAGPSSTESESRKRSISKRKSHLDLLKLIMDGMTEACIKGGI 420
            EAIKIMKEILGSPQRLCDLAGPSSTESESRKRSISKRKSHLDLLKLIMDGMTEACIKGGI
Sbjct: 361  EAIKIMKEILGSPQRLCDLAGPSSTESESRKRSISKRKSHLDLLKLIMDGMTEACIKGGI 420

Query: 421  EACYAAVSCVCTLLGALDELSQGKGLSEGQVQLLLLRLEELKDGAEWSRDSMEINEADFR 480
            EACYAAVSCVCTLLGALDELSQGKGLSEGQVQLLLLRLEELKDGAEWSRDSMEINEADFR
Sbjct: 421  EACYAAVSCVCTLLGALDELSQGKGLSEGQVQLLLLRLEELKDGAEWSRDSMEINEADFR 480

Query: 481  WQRRVLSSEHTPWESGNERSLDISISVTTDTGQTTLEGELGQTTPEDHSGNHKNSLKSPA 540
            WQRRVLSSEHTPWESGNERSLDISISVTTDTGQTTLEGELGQTTPEDHSGNHKNSLKSPA
Sbjct: 481  WQRRVLSSEHTPWESGNERSLDISISVTTDTGQTTLEGELGQTTPEDHSGNHKNSLKSPA 540

Query: 541  IPEGKETLSKVLETEAVDQPDVVQRSHTVPYPDITNFLSVDCRTRSYGSRYSESNFSVDD 600
            IPEGKETLSKVLETEAVDQPDVVQRSHTVPYPDITNFLSVDCRTRSYGSRYSESNFSVDD
Sbjct: 541  IPEGKETLSKVLETEAVDQPDVVQRSHTVPYPDITNFLSVDCRTRSYGSRYSESNFSVDD 600

Query: 601  QDLSRTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGHRSLRTAALSL 660
            QDLSRTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGHRSLRTAALSL
Sbjct: 601  QDLSRTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGHRSLRTAALSL 660

Query: 661  KLLKNQEADQHSARLFIQSLEGLLPRLLSLSNVEEVDTALQNFASTFCSGMMHSPGFDGN 720
            KLLKNQEADQHSARLFIQSLEGLLPRLLSLSNVEEVDTALQNFASTFCSGMMHSPGFDGN
Sbjct: 661  KLLKNQEADQHSARLFIQSLEGLLPRLLSLSNVEEVDTALQNFASTFCSGMMHSPGFDGN 720

Query: 721  SSLSFQMLMNADSLYTAAHCALLLNLKLSHGDYYRKRPTLAPGVMKDFMKQVQTSGVLMV 780
            SSLSFQMLMNADSLYTAAHCALLLNLKLSHGDYYRKRPTLAPGVMKDFMKQVQTSGVLMV
Sbjct: 721  SSLSFQMLMNADSLYTAAHCALLLNLKLSHGDYYRKRPTLAPGVMKDFMKQVQTSGVLMV 780

Query: 781  FSQAWIEELYHQVLDRNMLGEAGYWGSPEDNSLPLITMLTDIDGLESSAIGGQLMASAAT 840
            FSQAWIEELYHQVLDRNMLGEAGYWGSPEDNSLPLITMLTDIDGLESSAIGGQLMASAAT
Sbjct: 781  FSQAWIEELYHQVLDRNMLGEAGYWGSPEDNSLPLITMLTDIDGLESSAIGGQLMASAAT 840

Query: 841  ESPFAQSRRIDDSTVAGVAFARYILVGCWKNLIDTLSTPLTGRMAGSSKGLAFILGAEGI 900
            ESPFAQSRRIDDSTVAGVAFARYILVGCWKNLIDTLSTPLTGRMAGSSKGLAFILGAEGI
Sbjct: 841  ESPFAQSRRIDDSTVAGVAFARYILVGCWKNLIDTLSTPLTGRMAGSSKGLAFILGAEGI 900

Query: 901  KEQNQKERDAICMSLDGLRKAARLSCALGVAANCASALAQMAAASCVQEEKEEREAQEPS 960
            KEQNQKERDAICMSLDGLRKAARLSCALGVAANCASALAQMAAASCVQEEKEEREAQEPS
Sbjct: 901  KEQNQKERDAICMSLDGLRKAARLSCALGVAANCASALAQMAAASCVQEEKEEREAQEPS 960

Query: 961  DAITQVKLKVEQKLEQIGKVQGVWLHTAHVLCMEAILSVGLEMGSHNPDCWPHVFRVCEY 1020
            DAITQVKLKVEQKLEQIGKVQGVWLHTAHVLCMEAILSVGLEMGSHNPDCWPHVFRVCEY
Sbjct: 961  DAITQVKLKVEQKLEQIGKVQGVWLHTAHVLCMEAILSVGLEMGSHNPDCWPHVFRVCEY 1020

Query: 1021 VGTLEHNHFSDGASQPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQGRSLSTAPVVQ 1080
            VGTLEHNHFSDGASQPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQGRSLSTAPVVQ
Sbjct: 1021 VGTLEHNHFSDGASQPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQGRSLSTAPVVQ 1080

Query: 1081 PLSIQDLVREGSRGRASDFRGGSLMSGSSAAKVVLTLSTQADRLFEDATDKLNLMALGGF 1140
            PLSIQDLVREGSRGRASDFRGGSLMSGSSAAKVVLTLSTQADRLFEDATDKLNLMALGGF
Sbjct: 1081 PLSIQDLVREGSRGRASDFRGGSLMSGSSAAKVVLTLSTQADRLFEDATDKLNLMALGGF 1140

Query: 1141 LYQLKKASQSQLFHSVTDTVDYSLAMPGEVKSTQDRKSALHLFRLGNAMLRIVRSKARPL 1200
            LYQLKKASQSQLFHSVTDTVDYSLAMPGEVKSTQDRKSALHLFRLGNAMLRIVRSKARPL
Sbjct: 1141 LYQLKKASQSQLFHSVTDTVDYSLAMPGEVKSTQDRKSALHLFRLGNAMLRIVRSKARPL 1200

Query: 1201 LHVMRCWSLVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPF 1260
            LHVMRCWSLVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPF
Sbjct: 1201 LHVMRCWSLVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPF 1260

Query: 1261 ERIMQLELCDEDVQDQVVTSIGELVEVCSTQIQSGWRPLFSALETVHGGNKSEMKEYLVG 1320
            ERIMQLELCDEDVQDQVVTSIGELVEVCSTQIQSGWRPLFSALETVHGGNKSEMKEYLVG
Sbjct: 1261 ERIMQLELCDEDVQDQVVTSIGELVEVCSTQIQSGWRPLFSALETVHGGNKSEMKEYLVG 1320

Query: 1321 DYSMGKGQAPVFDVFEAFLNTDNIQVFANAATSYIMCLMKFVKGLGEVDCKEIGDCAPAP 1380
            DYSMGKGQAPVFDVFEAFLNTDNIQVFANAATSYIMCLMKFVKGLGEVDCKEIGDCAPAP
Sbjct: 1321 DYSMGKGQAPVFDVFEAFLNTDNIQVFANAATSYIMCLMKFVKGLGEVDCKEIGDCAPAP 1380

Query: 1381 GAPSTDLCLPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIESV 1440
            GAPSTDLCLPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIESV
Sbjct: 1381 GAPSTDLCLPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIESV 1440

Query: 1441 LSDFDDDTGLIEVWIILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGFGIYAV 1500
            LSDFDDDTGLIEVWIILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGFGIYAV
Sbjct: 1441 LSDFDDDTGLIEVWIILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGFGIYAV 1500

Query: 1501 VHLLLPVMSVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQSFLHSDIRYESMINT 1560
            VHLLLPVMSVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQSFLHSDIRYESMINT
Sbjct: 1501 VHLLLPVMSVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQSFLHSDIRYESMINT 1560

Query: 1561 MLKDLFELLVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSATLK 1620
            MLKDLFELLVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSATLK
Sbjct: 1561 MLKDLFELLVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSATLK 1620

Query: 1621 PVKDLLGCFHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSPKTP 1680
            PVKDLLGCFHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSPKTP
Sbjct: 1621 PVKDLLGCFHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSPKTP 1680

Query: 1681 NNFDHAQSCQLIIELPPDEKPNGHTKKSVSFREIVVSLLSHQVLLQNLYDILLEEFVKGP 1740
            NNFDHAQSCQLIIELPPDEKPNGHTKKSVSFREIVVSLLSHQVLLQNLYDILLEEFVKGP
Sbjct: 1681 NNFDHAQSCQLIIELPPDEKPNGHTKKSVSFREIVVSLLSHQVLLQNLYDILLEEFVKGP 1740

Query: 1741 SPGEEKTIQVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDTSPGLKCLLKKVSGI 1800
            SPGEEKTIQVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDTSPGLKCLLKKVSGI
Sbjct: 1741 SPGEEKTIQVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDTSPGLKCLLKKVSGI 1800

Query: 1801 GGAANLYRQSAMSFNIYFHALVCAVLTNQETITAEQVKKVLFEDDERSTDSSQQCSSEDE 1860
            GGAANLYRQSAMSFNIYFHALVCAVLTNQETITAEQVKKVLFEDDERSTDSSQQCSSEDE
Sbjct: 1801 GGAANLYRQSAMSFNIYFHALVCAVLTNQETITAEQVKKVLFEDDERSTDSSQQCSSEDE 1860

Query: 1861 DIFEETAQVSPPRGKEKRQWRARMPLLSVQPVSNADWVWLVKRLHKLCMELCNNYIQMHL 1920
            DIFEETAQVSPPRGKEKRQWRARMPLLSVQPVSNADWVWLVKRLHKLCMELCNNYIQMHL
Sbjct: 1861 DIFEETAQVSPPRGKEKRQWRARMPLLSVQPVSNADWVWLVKRLHKLCMELCNNYIQMHL 1920

Query: 1921 DLENCMEEPPIFKGDPFFILPSFQSESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLK 1980
            DLENCMEEPPIFKGDPFFILPSFQSESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLK
Sbjct: 1921 DLENCMEEPPIFKGDPFFILPSFQSESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLK 1980

Query: 1981 AGGGDLLLPPSPKVEKKDPSRKKEWWENAGNKIYTMAADKTISKLMTEYKKRKQQHNLSA 2040
            AGGGDLLLPPSPKVEKKDPSRKKEWWENAGNKIYTMAADKTISKLMTEYKKRKQQHNLSA
Sbjct: 1981 AGGGDLLLPPSPKVEKKDPSRKKEWWENAGNKIYTMAADKTISKLMTEYKKRKQQHNLSA 2040

Query: 2041 FPKEVKVEKKGEPLGPRGQDSPLLQRPQHLMDQGQMRHSFSAGPELLRQDKRPRSGSTGS 2100
            FPKEVKVEKKGEPLGPRGQDSPLLQRPQHLMDQGQMRHSFSAGPELLRQDKRPRSGSTGS
Sbjct: 2041 FPKEVKVEKKGEPLGPRGQDSPLLQRPQHLMDQGQMRHSFSAGPELLRQDKRPRSGSTGS 2100

Query: 2101 SLSVSVRDAEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIRVRQ 2160
            SLSVSVRDAEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIRVRQ
Sbjct: 2101 SLSVSVRDAEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIRVRQ 2160

Query: 2161 AVREWLGRVGRVYDIIV 2177
            AVREWLGRVGRVYDIIV
Sbjct: 2161 AVREWLGRVGRVYDIIV 2177


>gi|51479145 brefeldin A-inhibited guanine nucleotide-exchange protein
            1 [Homo sapiens]
          Length = 1849

 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 132/654 (20%), Positives = 252/654 (38%), Gaps = 102/654 (15%)

Query: 1205 RCWSLVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPFERIM 1264
            R W ++  H  +  C+    V+  AV  +  +  + L +  E  +F F +   RPFE IM
Sbjct: 1186 RIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFL-EKGELANFRFQKDFLRPFEHIM 1244

Query: 1265 QLELCDEDVQDQVVTSIGELVEVCSTQIQSGWRPLFSALETVHGGNKSEMKEYLVGDYSM 1324
            +       ++D VV  I ++V   +  I+SGW+ +FS            + E        
Sbjct: 1245 KRNR-SPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVEL------- 1296

Query: 1325 GKGQAPVFDVFEAFLNTDNIQ--VFANAATSYIMCLMKFVKGLGEVDCKEIGDCAPAPGA 1382
                        AF  T +I   VF     + I      VK L E  C           A
Sbjct: 1297 ------------AFQTTGHIVTLVFEKHFPATIDSFQDAVKCLSEFACN----------A 1334

Query: 1383 PSTDLCLPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIESVLS 1442
               D  + A+  +R C++             ++S R    P+  +E ++         ++
Sbjct: 1335 AFPDTSMEAIRLIRHCAK-------------YVSDR----PQAFKEYTSDD-------MN 1370

Query: 1443 DFDDDTGLIEVWIILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGF--GIYAV 1500
               +D   +  W  +L +L+  ++ C    +   L ++FE+++    T    +   ++ +
Sbjct: 1371 VAPEDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFRI 1430

Query: 1501 VHLLLPVMSVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQSFLHSDIRYESMINT 1560
            V  +   M +  +++ K  + W   + N  HA+   C++  +++          E + + 
Sbjct: 1431 VFRIFDNMKLPEQQTEK--AEWMTTTCN--HALYAICDVFTQYL----------EVLSDV 1476

Query: 1561 MLKDLFELLVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSATLK 1620
            +L D+F  L  CV +  E ++R G +C+  V++  G  FT E+W   C    D F  T+ 
Sbjct: 1477 LLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTI- 1535

Query: 1621 PVKDLLGCFHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSPKTP 1680
            P   L    +SG             A P  SP +E     +  ++Q+   +     P++ 
Sbjct: 1536 PHALLTWRPNSG-----------ETAPPPPSPVSEKP---LDTISQKSVDIHDSIQPRSV 1581

Query: 1681 NNFDHAQ--SCQLIIELPPDEKPNGHTKKSVSFREIVVSLLSHQVLLQNLYDILL----- 1733
            +N   A   S   + E     K      +   F  +++  +    L+Q + +I+      
Sbjct: 1582 DNRPQAPLVSASAVNEEVSKIKSTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATS 1641

Query: 1734 -----EEFVKGPSPGEEKTIQVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDTSP 1788
                 E          +  ++V + +  G  R+++ Q L  + D LL+S+R A+ F+++ 
Sbjct: 1642 KKEDAENLAAAQRDAVDFDVRV-DTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNN 1700

Query: 1789 GLKCLLKKVSGIG-GAANLYRQSAMSFNIYFHALVCAVLTNQETITAEQVKKVL 1841
              +  L K    G    NL +Q   S       L    +        E+V++ L
Sbjct: 1701 EQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYMDESRVSAWEEVQQRL 1754



 Score = 58.5 bits (140), Expect = 7e-08
 Identities = 53/225 (23%), Positives = 105/225 (46%), Gaps = 44/225 (19%)

Query: 1   MEEILRKLQKEASGSKYKAIKESCTWALETLGGLDTIVKIPPH----------------- 43
           +E+IL    KE   + +  ++++C  ALE +   +T  + PPH                 
Sbjct: 16  LEKILA--DKEVKKAHHSQLRKACEVALEEIKA-ETEKQSPPHGEAKAGSSTLPPVKSKT 72

Query: 44  --VLREKCLLPLQLALESKNVKLAQHALAGMQKLLSEERFVSMETDSDE--KQLLNQILN 99
             +  +K  LP +LA +SK  ++   +L  +QKL++         DS    K+L+++I+ 
Sbjct: 73  NFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGNAPDSTTPGKKLIDRIIE 132

Query: 100 AV---KVTPSLNEDLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSIN 156
            +      P  +E +Q++++K LL    +   +++   VL+    C   Y++S  +  IN
Sbjct: 133 TICGCFQGPQTDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLAS--KNLIN 190

Query: 157 -TAVRATLSQMLSDLTLQL--------------RQRQENTIIENP 186
            T  +ATL+QML+ +  ++              R RQ + ++++P
Sbjct: 191 QTTAKATLTQMLNVIFARMENQALQEAKQMEKERHRQHHHLLQSP 235



 Score = 33.9 bits (76), Expect = 1.8
 Identities = 17/67 (25%), Positives = 34/67 (50%)

Query: 2109 AEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIRVRQAVREWLGR 2168
            +E+  +AWTN++L  L ++  + D  F A     +P + ++        +R  +R +  R
Sbjct: 1770 SESHREAWTNLLLLFLTKVLKISDNRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLR 1829

Query: 2169 VGRVYDI 2175
            +G V+ I
Sbjct: 1830 IGVVFQI 1836


>gi|150417986 ADP-ribosylation factor guanine nucleotide-exchange
            factor 2 [Homo sapiens]
          Length = 1785

 Score = 91.7 bits (226), Expect = 7e-18
 Identities = 127/628 (20%), Positives = 242/628 (38%), Gaps = 121/628 (19%)

Query: 1205 RCWSLVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPFERIM 1264
            R W ++  H  +  C+    V+  AV  +  +  + L +  E  +F F +   RPFE IM
Sbjct: 1133 RIWHVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFL-EKGELANFRFQKDFLRPFEHIM 1191

Query: 1265 QLELCDEDVQDQVVTSIGELVEVCSTQIQSGWRPLFSALETV---HGGNKSEMKEYLVGD 1321
            +       ++D  +  I ++V   +  I+SGW+ +F+        H GN  E+       
Sbjct: 1192 KKNR-SPTIRDMAIRCIAQMVNSQAANIRSGWKNIFAVFHQAASDHDGNIVEL------- 1243

Query: 1322 YSMGKGQAPVFDVFEAFLNTDNI--QVFANAATSYIMCLMKFVKGLGEVDCKEIGDCAPA 1379
                           AF  T +I   +F +   + I      VK L E  C         
Sbjct: 1244 ---------------AFQTTCHIVTTIFQHHFPAAIDSFQDAVKCLSEFACN-------- 1280

Query: 1380 PGAPSTDLCLPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIES 1439
              A   D  + A+  +R C + +++                  PR LQE ++        
Sbjct: 1281 --AAFPDTSMEAIRLIRFCGKYVSE-----------------RPRVLQEYTSDD------ 1315

Query: 1440 VLSDFDDDTGLIEVWIILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGF--GI 1497
             ++    D   +  W  +L +L+  ++ C    +   L ++FE+++    T    +   +
Sbjct: 1316 -MNVAPGDRVWVRGWFPILFELSCIINRCKLDVRTRGLTVMFEIMKSYGHTFEKHWWQDL 1374

Query: 1498 YAVVHLLLPVMSVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQSFLHSDIRYESM 1557
            + +V  +   M +  + S K  S W   + N  HA+   C++  +           YE++
Sbjct: 1375 FRIVFRIFDNMKLPEQLSEK--SEWMTTTCN--HALYAICDVFTQF----------YEAL 1420

Query: 1558 INTMLKDLFELLVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSA 1617
               +L D+F  L  CV +  E ++R G +C+  ++++ G  F+ E+W   C  + D F  
Sbjct: 1421 NEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPEVWDETCNCMLDIFKT 1480

Query: 1618 TLKPVKDLLGCFHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSP 1677
            T+  V  LL     G E  S E                 ++  +    Q +  +D     
Sbjct: 1481 TIPHV--LLTWRPVGMEEDSSE-----------------KHLDVDLDRQSLSSID----- 1516

Query: 1678 KTPNNFDHAQSCQLIIELPPDEKPNGHTKKSVS-FREIVVSLLSHQVLLQNLYDILL--- 1733
            K P+    +Q     +  P D+   G    +   F  +++  +    L+Q + +I+    
Sbjct: 1517 KNPSERGQSQ-----LSNPTDDSWKGRPYANQKLFASLLIKCVVQLELIQTIDNIVFYPA 1571

Query: 1734 -------EEFVKGPSPGEEKTIQVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDT 1786
                   E  V       +  I + E +  G  +Y+S Q+L  + D L +S+  ++ F++
Sbjct: 1572 TSKKEDAEHMVAAQQDTLDADIHI-ETEDQGMYKYMSSQHLFKLLDCLQESHSFSKAFNS 1630

Query: 1787 SPGLKCLLKKVSGIG-GAANLYRQSAMS 1813
            +   + +L +    G    NL +Q   S
Sbjct: 1631 NYEQRTVLWRAGFKGKSKPNLLKQETSS 1658



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 50/201 (24%), Positives = 101/201 (50%), Gaps = 19/201 (9%)

Query: 1   MEEILRKLQKEASGSKYKAIKESCTWALETLGGLDTIVKI----PPH---VLREKCLLPL 53
           +E+IL    KE    ++  ++ +C  AL+ +       ++    PP    +  +K  LP 
Sbjct: 15  LEKILA--DKEVKRPQHSQLRRACQVALDEIKAEIEKQRLGTAAPPKANFIEADKYFLPF 72

Query: 54  QLALESKNVKLAQHALAGMQKLLSEERFVSMETDSDE--KQLLNQILNAVKVT---PSLN 108
           +LA +SK+ ++   +L  +QKL++         DS    K+L+++I+  +      P  +
Sbjct: 73  ELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETICSCFQGPQTD 132

Query: 109 EDLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSIN-TAVRATLSQML 167
           E +Q++++K LL    +P  +++   +L+    C   Y++S  +  IN T  +ATL+QML
Sbjct: 133 EGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLAS--KNLINQTTAKATLTQML 190

Query: 168 SDLTLQLRQR--QENTIIENP 186
           + +  ++  +  QE   +E P
Sbjct: 191 NVIFTRMENQVLQEARELEKP 211


>gi|114326552 MON2 homolog [Homo sapiens]
          Length = 1717

 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 64/300 (21%), Positives = 133/300 (44%), Gaps = 30/300 (10%)

Query: 1   MEEILRKLQKEASGSKYKAIKESCTWAL---ETLGGLDTIVKIPPHVLREKCLLPLQLAL 57
           M+  LR L  E    K+  +KE+    +   +T+   +T +         + + P  +  
Sbjct: 17  MQSDLRALSLECK-KKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGC 75

Query: 58  ESKNVKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNAVKVTPSLNEDLQVEVMK 117
            +K  K+ Q  LA +Q+L+S E    + +++    ++N +   ++     N   ++++++
Sbjct: 76  GTKEPKITQLCLAAIQRLMSHE----VVSETAAGNIINMLWQLME-----NSLEELKLLQ 126

Query: 118 VLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSDLTLQLRQR 177
            +L +  T T  ++  A+ K   +C   + +       N    AT+ Q+++ +  ++   
Sbjct: 127 TVLVLLTTNTV-VHDEALSKAIVLCFRLHFTK--DNITNNTAAATVRQVVTVVFERMVAE 183

Query: 178 QEN--TIIENPDVPQDFGNQGS--TVESLCDDVVSVLTVLCEKLQA-----AINDSQQLQ 228
            E    IIE P + Q   N+ S  T++    D   +   LC+ + A      +  ++  +
Sbjct: 184 DERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTR 243

Query: 229 LLYLECILSVLSSSSSSMHLHRRFTDLIWKNLCPALIVILGNPIHDKTITSAHTSSTSTS 288
              LE + SVL+        H+ F+ L+ + +CP L++ L +P     I     SSTS+S
Sbjct: 244 TFGLELLESVLNDFPQVFLQHQEFSFLLKERVCP-LVIKLFSP----NIKFRQGSSTSSS 298


>gi|195927059 axin 2 [Homo sapiens]
          Length = 843

 Score = 33.9 bits (76), Expect = 1.8
 Identities = 23/95 (24%), Positives = 46/95 (48%), Gaps = 4/95 (4%)

Query: 2014 YTMAADKTISKLMTEYKKRKQQHNLSAFPKEVKVEKKGEPLGPRGQDSPLLQRPQHLMDQ 2073
            Y + + K + + M    K   Q +L  FP+  ++ K+  P+ P    + L+ R + L  +
Sbjct: 325  YRVGSKKQLQREMHRSVKANGQVSLPHFPRTHRLPKEMTPVEPATFAAELISRLEKLKLE 384

Query: 2074 GQMRHSFSAGPELLRQDKRPRSGSTGSSLSVSVRD 2108
             + RHS     + +R+D+       GS L+++ R+
Sbjct: 385  LESRHSLEERLQQIREDEE----REGSELTLNSRE 415


>gi|63055059 SH3 and PX domains 2B [Homo sapiens]
          Length = 911

 Score = 33.9 bits (76), Expect = 1.8
 Identities = 26/93 (27%), Positives = 40/93 (43%), Gaps = 4/93 (4%)

Query: 1036 PPLTISQPQKATGSAGLLGD---PECEGSPPEHSPEQGRSLSTAPVVQPLSIQDL-VREG 1091
            PP     P+K + S+  L +   P+CEG     +P  GR+L   P  +P     L  ++ 
Sbjct: 758  PPRRPPPPKKTSSSSRPLPEVRGPQCEGHESRAAPTPGRALLVPPKAKPFLSNSLGGQDD 817

Query: 1092 SRGRASDFRGGSLMSGSSAAKVVLTLSTQADRL 1124
            +RG+ S    G+   G +  K        AD L
Sbjct: 818  TRGKGSLGPWGTGKIGENREKAAAASVPNADGL 850


>gi|239757530 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 33.1 bits (74), Expect = 3.1
 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%)

Query: 533 KNSLKSPAIPEGKETLSKVLETEAVDQPDVVQ-RSHTVPYPDITNFLSVDCRTRSYGSRY 591
           KN       P GK +++    T   D  DV+Q +S      D T+ +    + +S  +  
Sbjct: 208 KNLTGEVCFPTGKTSIA----TAQSDPMDVMQDQSIATAQSDPTDVM----QDQSIATAQ 259

Query: 592 SESNFSVDDQDLSRTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGHR 651
           S+    + DQ ++  + D  D     +   + RSD +D+  D  S+A  +  P D +  +
Sbjct: 260 SDPTDVMQDQSIATAQSDPTDVMQDQSIATAQRSDPTDVMQDQ-SIATAQSDPTDVMQDQ 318

Query: 652 SLRTA 656
           S+ TA
Sbjct: 319 SIATA 323


>gi|239752052 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 33.1 bits (74), Expect = 3.1
 Identities = 31/125 (24%), Positives = 55/125 (44%), Gaps = 10/125 (8%)

Query: 533 KNSLKSPAIPEGKETLSKVLETEAVDQPDVVQ-RSHTVPYPDITNFLSVDCRTRSYGSRY 591
           KN       P GK +++    T   D  DV+Q +S      D T+ +    + +S  +  
Sbjct: 208 KNLTGEVCFPTGKTSIA----TAQSDPMDVMQDQSIATAQSDPTDVM----QDQSIATAQ 259

Query: 592 SESNFSVDDQDLSRTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGHR 651
           S+    + DQ ++  + D  D     +   + RSD +D+  D  S+A  +  P D +  +
Sbjct: 260 SDPTDVMQDQSIATAQSDPTDVMQDQSIATAQRSDPTDVMQDQ-SIATAQSDPTDVMQDQ 318

Query: 652 SLRTA 656
           S+ TA
Sbjct: 319 SIATA 323


>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
          Length = 2964

 Score = 33.1 bits (74), Expect = 3.1
 Identities = 39/154 (25%), Positives = 64/154 (41%), Gaps = 8/154 (5%)

Query: 248 LHRRFTDLIWKNLCPALIVILGNPIHDKTITSAHTSSTSTSLESDSASPGVSDHGRGSGC 307
           L RR   L  K+  P+L ++  +        + H  S+S  + SD  S  +    RG   
Sbjct: 775 LKRRLPKLS-KSTAPSLALLADSEKPSHKSFATHKLSSSMCVSSDLLSD-IYKPKRGRPK 832

Query: 308 SCTAPALSGPVARTIYYIAAELVRLVGSVDSMKPVLQ------SLYHRVLLYPPPQHRVE 361
           S   P L GP  RT+   A+++  L    +   P+LQ      S    + + P P+ R  
Sbjct: 833 SKEMPQLEGPPKRTLKIPASKVFSLQSKEEQEPPILQPEIEIPSFKQGLSVSPFPKKRGR 892

Query: 362 AIKIMKEILGSPQRLCDLAGPSSTESESRKRSIS 395
             + M+  +     +  +A   +TES S+  S S
Sbjct: 893 PKRQMRSPVKMKPPVLSVAPFVATESPSKLESES 926


>gi|55749621 pleckstrin homology domain containing, family G, member 3
            [Homo sapiens]
          Length = 1163

 Score = 33.1 bits (74), Expect = 3.1
 Identities = 32/144 (22%), Positives = 62/144 (43%), Gaps = 15/144 (10%)

Query: 1935 DPFFILPSFQ-----SESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLKAGGGDLLLP 1989
            +P FIL   +      ES+T S    S  E  S    ++  + + + LS  +  G+L+ P
Sbjct: 788  EPLFILEEHELGAITEESATASPESSSPTEGRSPAHLARELKELVKELS-SSTQGELVAP 846

Query: 1990 PSPKVEKKDPSRKKEWWENAGNKIYTMAADKTI---------SKLMTEYKKRKQQHNLSA 2040
              P++ +          E   NK+Y +A   ++         ++   +++K   + +  +
Sbjct: 847  LHPRIVQLSHVMDSHVSERVKNKVYQLARQYSLRIKSNKPVMARPPLQWEKVAPERDGKS 906

Query: 2041 FPKEVKVEKKGEPLGPRGQDSPLL 2064
                   E+ GEPLG +G+  P+L
Sbjct: 907  PTVPCLQEEAGEPLGGKGKRKPVL 930


>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
            sapiens]
          Length = 870

 Score = 32.7 bits (73), Expect = 4.0
 Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 2/75 (2%)

Query: 1988 LPPSPKVEKKDPSRKKEWWENAGNKIYTMAADKTISKLMTEYKKRKQQHNLSAFPKEVKV 2047
            LP SPK  KKDP+++    E  G              L  EY      +  S+ P E++V
Sbjct: 143  LPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYP-SSLPPELRV 201

Query: 2048 EKKGEPLGPRGQDSP 2062
             K  EP GP  Q  P
Sbjct: 202  -KSDEPPGPSEQVGP 215


>gi|24497533 homeobox C10 [Homo sapiens]
          Length = 342

 Score = 32.7 bits (73), Expect = 4.0
 Identities = 32/135 (23%), Positives = 52/135 (38%), Gaps = 12/135 (8%)

Query: 1874 GKEKRQWRARMPLLSVQPVSNADWVWLVKRLHKLCMELCNNY--------IQMHLDLENC 1925
            G  K  +R   P+   +P+S+  +   VK  +  CM              +  H   E+C
Sbjct: 80   GDPKAAYRLEQPV--GRPLSSCSYPPSVKEENVCCMYSAEKRAKSGPEAALYSHPLPESC 137

Query: 1926 MEEPPIFKGDPFFILPSFQSESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLKAGGGD 1985
            + E  +     +   PS+ +   TP   G +  E P E  +  S     E L     GG 
Sbjct: 138  LGEHEVPVPSYYRASPSYSALDKTPHCSGANDFEAPFE--QRASLNPRAEHLESPQLGGK 195

Query: 1986 LLLPPSPKVEKKDPS 2000
            +  P +PK + + PS
Sbjct: 196  VSFPETPKSDSQTPS 210


>gi|221316754 exophilin 5 isoform c [Homo sapiens]
          Length = 1801

 Score = 32.3 bits (72), Expect = 5.2
 Identities = 16/44 (36%), Positives = 23/44 (52%)

Query: 526 EDHSGNHKNSLKSPAIPEGKETLSKVLETEAVDQPDVVQRSHTV 569
           ED  GN+  +  SP+ PE     SKVL   A++ P+  +R   V
Sbjct: 871 EDAMGNYMLNKFSPSSPESANECSKVLSDSALEAPEATERMTNV 914


>gi|221316751 exophilin 5 isoform b [Homo sapiens]
          Length = 1913

 Score = 32.3 bits (72), Expect = 5.2
 Identities = 16/44 (36%), Positives = 23/44 (52%)

Query: 526  EDHSGNHKNSLKSPAIPEGKETLSKVLETEAVDQPDVVQRSHTV 569
            ED  GN+  +  SP+ PE     SKVL   A++ P+  +R   V
Sbjct: 983  EDAMGNYMLNKFSPSSPESANECSKVLSDSALEAPEATERMTNV 1026


>gi|16753205 ubiquilin 1 isoform 2 [Homo sapiens]
          Length = 561

 Score = 32.3 bits (72), Expect = 5.2
 Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 364 KIMKEILGSPQRLCDLAGPSSTESESRKRSISKR-KSHLDLLKLIMDG 410
           KIMK  + +P+   + A P ++  +  K  ISKR KSH D L LI  G
Sbjct: 35  KIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAG 82


>gi|16753203 ubiquilin 1 isoform 1 [Homo sapiens]
          Length = 589

 Score = 32.3 bits (72), Expect = 5.2
 Identities = 20/48 (41%), Positives = 27/48 (56%), Gaps = 1/48 (2%)

Query: 364 KIMKEILGSPQRLCDLAGPSSTESESRKRSISKR-KSHLDLLKLIMDG 410
           KIMK  + +P+   + A P ++  +  K  ISKR KSH D L LI  G
Sbjct: 35  KIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAG 82


>gi|19924103 synapsin II isoform IIa [Homo sapiens]
          Length = 582

 Score = 32.3 bits (72), Expect = 5.2
 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 5/36 (13%)

Query: 1035 QPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQG 1070
            Q PLT  QPQ     +G L DP+   +PP+  P QG
Sbjct: 427  QRPLTTQQPQ-----SGTLKDPDSSKTPPQRPPPQG 457


>gi|221316747 exophilin 5 isoform a [Homo sapiens]
          Length = 1989

 Score = 32.3 bits (72), Expect = 5.2
 Identities = 16/44 (36%), Positives = 23/44 (52%)

Query: 526  EDHSGNHKNSLKSPAIPEGKETLSKVLETEAVDQPDVVQRSHTV 569
            ED  GN+  +  SP+ PE     SKVL   A++ P+  +R   V
Sbjct: 1059 EDAMGNYMLNKFSPSSPESANECSKVLSDSALEAPEATERMTNV 1102


>gi|19924101 synapsin II isoform IIb [Homo sapiens]
          Length = 478

 Score = 32.3 bits (72), Expect = 5.2
 Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 5/36 (13%)

Query: 1035 QPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQG 1070
            Q PLT  QPQ     +G L DP+   +PP+  P QG
Sbjct: 427  QRPLTTQQPQ-----SGTLKDPDSSKTPPQRPPPQG 457


>gi|21327710 nucleosome assembly protein 1-like 3 [Homo sapiens]
          Length = 506

 Score = 32.0 bits (71), Expect = 6.8
 Identities = 32/164 (19%), Positives = 61/164 (37%), Gaps = 8/164 (4%)

Query: 1844 DDERSTDSSQQCSSEDEDIFEETAQVSPPRGKEKRQWRARMPLLSVQPVSNADWVWLVKR 1903
            ++E   +S  +  S DE++ + T    PP   E+ +     P +  +       +  VK 
Sbjct: 159  EEECEWNSEDEEFSSDEEVQDNTPSEMPPLEGEEEENPKENPEVKAEEKEVPKEIPEVKD 218

Query: 1904 LHK-LCMELCNNYIQMHLDLENCMEEPPIFKGDPFFILPSFQSESSTPSTGGFSGKETPS 1962
              K +  E+     +   D ++CME  P  K DP  +      +   P       +    
Sbjct: 219  EEKEVPKEIPEVKAEEKADSKDCMEATPEVKEDPKEVPQVKADDKEQPKATEAKARAAVR 278

Query: 1963 EDDRSQSREHMGESLSLKAGGGDLLLPPSPKVEKKDPSRKKEWW 2006
            E  +    E + +S+ LK            K +++DP    ++W
Sbjct: 279  ETHKRVPEERLQDSVDLKRA-------RKGKPKREDPKGIPDYW 315


>gi|38045915 pregnancy-associated plasma protein A preproprotein [Homo
            sapiens]
          Length = 1627

 Score = 32.0 bits (71), Expect = 6.8
 Identities = 19/60 (31%), Positives = 26/60 (43%)

Query: 1609 CALQDAFSATLKPVKDLLGCFHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQV 1668
            C+ Q    A LK    LL C   G  SF    C++   AP   P+A+ +  R R    +V
Sbjct: 1310 CSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKV 1369


>gi|7019477 HtrA serine peptidase 2 isoform 1 preproprotein [Homo
           sapiens]
          Length = 458

 Score = 32.0 bits (71), Expect = 6.8
 Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 8/144 (5%)

Query: 126 PTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSDLTLQLRQRQENTIIEN 185
           PT  L  SA ++  E  +        Q +I + + ++  +   DL L     Q N     
Sbjct: 241 PTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLP----QTNVEYIQ 296

Query: 186 PDVPQDFGNQGSTVESLCDDVVSVLTV-LCEKLQAAINDSQQLQLLYLECILSVLSSSSS 244
            D   DFGN G  + +L  +V+ V T+ +   +  AI   +  + L+        +SSS 
Sbjct: 297 TDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRG---EKKNSSSG 353

Query: 245 SMHLHRRFTDLIWKNLCPALIVIL 268
                RR+  ++   L P+++  L
Sbjct: 354 ISGSQRRYIGVMMLTLSPSILAEL 377


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score = 32.0 bits (71), Expect = 6.8
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 10/99 (10%)

Query: 928  LGVAANCASALAQMAAASCVQEEKEEREAQEPSDAITQVKLKVEQKLEQIGKVQGVWLHT 987
            L +  N +   AQ+   + +QE     EAQEP ++    K     +L+++          
Sbjct: 52   LSIQDNTSPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDEL---------M 102

Query: 988  AHVLCMEAILSVGLEMG-SHNPDCWPHVFRVCEYVGTLE 1025
            AH+  M+A ++V  + G  H PD   H   +   +G LE
Sbjct: 103  AHLTEMQAKVAVRADAGKKHLPDKQDHKASLDSMLGGLE 141


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score = 32.0 bits (71), Expect = 6.8
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 10/99 (10%)

Query: 928  LGVAANCASALAQMAAASCVQEEKEEREAQEPSDAITQVKLKVEQKLEQIGKVQGVWLHT 987
            L +  N +   AQ+   + +QE     EAQEP ++    K     +L+++          
Sbjct: 47   LSIQDNTSPLPAQLVYTTNIQELNVYSEAQEPKESPPPSKTSAAAQLDEL---------M 97

Query: 988  AHVLCMEAILSVGLEMG-SHNPDCWPHVFRVCEYVGTLE 1025
            AH+  M+A ++V  + G  H PD   H   +   +G LE
Sbjct: 98   AHLTEMQAKVAVRADAGKKHLPDKQDHKASLDSMLGGLE 136


>gi|53729363 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 32.0 bits (71), Expect = 6.8
 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 44  VLREKCLLPL-QLALESKNVKLAQHALAGMQKLLSEERFVSMET--DSDEKQLLNQILNA 100
           +L E C   L Q+A ES+   L Q A + M ++  +ERF  + +    D+ + ++QIL  
Sbjct: 392 MLTESCKNRLIQMAYESQRQNLVQQACSSMAEM--DERFQQILSWQQMDQNKAISQILQE 449

Query: 101 VKVTPSLNEDLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAV- 159
             +  +  E LQV+  K L+         L  + +L++ +  +E    S    S+   + 
Sbjct: 450 SAMQKAAFEALQVK--KDLMHRQIRSQIKLIETELLQLTQ--LELKRKSLDTESLQEMIS 505

Query: 160 --RATLSQMLSDLTLQLRQRQE 179
             R  LS +L  L  + +QR+E
Sbjct: 506 EQRWALSSLLQQLLKEKQQREE 527


>gi|53729361 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 32.0 bits (71), Expect = 6.8
 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 44  VLREKCLLPL-QLALESKNVKLAQHALAGMQKLLSEERFVSMET--DSDEKQLLNQILNA 100
           +L E C   L Q+A ES+   L Q A + M ++  +ERF  + +    D+ + ++QIL  
Sbjct: 392 MLTESCKNRLIQMAYESQRQNLVQQACSSMAEM--DERFQQILSWQQMDQNKAISQILQE 449

Query: 101 VKVTPSLNEDLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAV- 159
             +  +  E LQV+  K L+         L  + +L++ +  +E    S    S+   + 
Sbjct: 450 SAMQKAAFEALQVK--KDLMHRQIRSQIKLIETELLQLTQ--LELKRKSLDTESLQEMIS 505

Query: 160 --RATLSQMLSDLTLQLRQRQE 179
             R  LS +L  L  + +QR+E
Sbjct: 506 EQRWALSSLLQQLLKEKQQREE 527


>gi|53729359 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 32.0 bits (71), Expect = 6.8
 Identities = 38/142 (26%), Positives = 67/142 (47%), Gaps = 12/142 (8%)

Query: 44  VLREKCLLPL-QLALESKNVKLAQHALAGMQKLLSEERFVSMET--DSDEKQLLNQILNA 100
           +L E C   L Q+A ES+   L Q A + M ++  +ERF  + +    D+ + ++QIL  
Sbjct: 392 MLTESCKNRLIQMAYESQRQNLVQQACSSMAEM--DERFQQILSWQQMDQNKAISQILQE 449

Query: 101 VKVTPSLNEDLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAV- 159
             +  +  E LQV+  K L+         L  + +L++ +  +E    S    S+   + 
Sbjct: 450 SAMQKAAFEALQVK--KDLMHRQIRSQIKLIETELLQLTQ--LELKRKSLDTESLQEMIS 505

Query: 160 --RATLSQMLSDLTLQLRQRQE 179
             R  LS +L  L  + +QR+E
Sbjct: 506 EQRWALSSLLQQLLKEKQQREE 527


>gi|34335253 disks large-associated protein 4 isoform a [Homo
           sapiens]
          Length = 989

 Score = 31.6 bits (70), Expect = 8.9
 Identities = 36/166 (21%), Positives = 65/166 (39%), Gaps = 19/166 (11%)

Query: 501 LDISISVTTDTGQTTL---EGELGQTTPEDHSGNHKNSLKS----PAI--------PEGK 545
           + +++  +T++ Q T    +    + T +    N  +SL S    P++        PE  
Sbjct: 574 ISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGVAPAPEAP 633

Query: 546 ETLSKVLETEAVDQPDVVQRSHTVPYPDIT-NFLSVDCRTRSYGSRYSESNFSVDDQDLS 604
           E   K    ++         SH    P    + + +  RTR  GS  SE N       ++
Sbjct: 634 EPPPKHAALKSEQGTLTSSESHPEAAPKRKLSSIGIQERTRRNGSHLSEDNGPKAIDVMA 693

Query: 605 RTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGH 650
            +   S   +SM++ +D+  SD  D    +C     E++  DC  H
Sbjct: 694 PSSESSVPSHSMSSRRDTD-SDTQDANDSSCK--SSERSLPDCTPH 736


>gi|63054864 phosphoprotein associated with glycosphingolipid
           microdomains 1 [Homo sapiens]
          Length = 432

 Score = 31.6 bits (70), Expect = 8.9
 Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 3/78 (3%)

Query: 525 PEDHSGNHKNSLKSPAIPEGKETLSKVLETEAVDQPDVVQRSHTVPYPDITNFLSVDCRT 584
           P  HSG+H+N +    +P  KE  S+ + + A D P   +++  +   DI +  S     
Sbjct: 46  PRQHSGDHENLMN---VPSDKEMFSRSVTSLATDAPASSEQNGALTNGDILSEDSTLTCM 102

Query: 585 RSYGSRYSESNFSVDDQD 602
           + Y    + ++  +D QD
Sbjct: 103 QHYEEVQTSASDLLDSQD 120


>gi|157388902 semaphorin 4C [Homo sapiens]
          Length = 833

 Score = 31.6 bits (70), Expect = 8.9
 Identities = 40/130 (30%), Positives = 51/130 (39%), Gaps = 22/130 (16%)

Query: 955  EAQEPSDAITQVKLKVEQKLEQIGKVQGVWLHTAHVLCMEAILSVGLEMGSHNPDCWPHV 1014
            EA E   AI+  +  VE+K E I K +          C   I  +     SH   C  + 
Sbjct: 79   EALELQGAISW-EAPVEKKTECIQKGKN-----NQTECFNFIRFLQPYNASHLYVCGTYA 132

Query: 1015 FRV-CEYVG----TLEHNHFSDGASQPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQ 1069
            F+  C YV     TLEH  F DG  + P        A G AGLL D E       +S   
Sbjct: 133  FQPKCTYVNMLTFTLEHGEFEDGKGKCPY-----DPAKGHAGLLVDGEL------YSATL 181

Query: 1070 GRSLSTAPVV 1079
               L T P++
Sbjct: 182  NNFLGTEPII 191


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 84,057,506
Number of Sequences: 37866
Number of extensions: 3861115
Number of successful extensions: 12481
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 12439
Number of HSP's gapped (non-prelim): 62
length of query: 2177
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2059
effective length of database: 13,779,330
effective search space: 28371640470
effective search space used: 28371640470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.