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Search of human proteins with 15147348
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|15147348 fibroblast growth factor 8 isoform E precursor
[Homo sapiens]
(233 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo... 474 e-134
gi|15147346 fibroblast growth factor 8 isoform F precursor [Homo... 465 e-131
gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo ... 405 e-113
gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo... 401 e-112
gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens] 237 7e-63
gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens] 218 5e-57
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 74 8e-14
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 72 3e-13
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 72 5e-13
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 71 9e-13
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 68 6e-12
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 67 1e-11
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 64 1e-10
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 60 2e-09
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 57 1e-08
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 55 5e-08
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 55 5e-08
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 55 5e-08
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 55 5e-08
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 55 5e-08
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 55 5e-08
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 54 1e-07
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 54 1e-07
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 54 1e-07
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 54 1e-07
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 53 3e-07
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 49 4e-06
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens] 49 4e-06
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens] 49 5e-06
gi|4758362 fibroblast growth factor 11 [Homo sapiens] 48 6e-06
>gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo
sapiens]
Length = 233
Score = 474 bits (1219), Expect = e-134
Identities = 233/233 (100%), Positives = 233/233 (100%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV 60
MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV 60
Query: 61 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 120
TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA
Sbjct: 61 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 120
Query: 121 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 180
ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG
Sbjct: 121 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 180
Query: 181 SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 233
SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Sbjct: 181 SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 233
>gi|15147346 fibroblast growth factor 8 isoform F precursor [Homo
sapiens]
Length = 244
Score = 465 bits (1197), Expect = e-131
Identities = 233/244 (95%), Positives = 233/244 (95%), Gaps = 11/244 (4%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQ-------- 52
MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQ
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQVTVQSSPN 60
Query: 53 ---HVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETD 109
HVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETD
Sbjct: 61 FTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETD 120
Query: 110 TFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYM 169
TFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYM
Sbjct: 121 TFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYM 180
Query: 170 AFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWA 229
AFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWA
Sbjct: 181 AFTRKGRPRKGSKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWA 240
Query: 230 PEPR 233
PEPR
Sbjct: 241 PEPR 244
>gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo
sapiens]
Length = 215
Score = 405 bits (1041), Expect = e-113
Identities = 206/233 (88%), Positives = 206/233 (88%), Gaps = 18/233 (7%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV 60
MGSPRSALSCLLLHLLVLCLQAQ P QHVREQSLV
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQVTVQSSPNF------------------TQHVREQSLV 42
Query: 61 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 120
TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA
Sbjct: 43 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 102
Query: 121 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 180
ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG
Sbjct: 103 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 162
Query: 181 SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 233
SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Sbjct: 163 SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 215
>gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo
sapiens]
Length = 204
Score = 401 bits (1030), Expect = e-112
Identities = 204/233 (87%), Positives = 204/233 (87%), Gaps = 29/233 (12%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV 60
MGSPRSALSCLLLHLLVLCLQAQ HVREQSLV
Sbjct: 1 MGSPRSALSCLLLHLLVLCLQAQ-----------------------------HVREQSLV 31
Query: 61 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 120
TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA
Sbjct: 32 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 91
Query: 121 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 180
ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG
Sbjct: 92 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 151
Query: 181 SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 233
SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
Sbjct: 152 SKTRQHQREVHFMKRLPRGHHTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR 204
>gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
Length = 216
Score = 237 bits (604), Expect = 7e-63
Identities = 128/226 (56%), Positives = 157/226 (69%), Gaps = 27/226 (11%)
Query: 11 LLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLVTDQLSRRLIR 70
L L LL+LC Q Q P Q+VR+Q +TDQLSRR IR
Sbjct: 12 LCLQLLILCCQTQ------------------GENHPSPNFNQYVRDQGAMTDQLSRRQIR 53
Query: 71 TYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNK 130
YQLYSRTSGKHVQV +RI+A AEDG+ FAKLIVETDTFGSRVR++GAE+ YICMNK
Sbjct: 54 EYQLYSRTSGKHVQV-TGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNK 112
Query: 131 KGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREV 190
+GKLI K +GK KDCVFTEIVLENNYTA QNA++EGW+MAFTR+GRPR+ S++RQ+QRE
Sbjct: 113 RGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREA 172
Query: 191 HFMKRLPRGH----HTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEP 232
HF+KRL +G + E+ +FEF+ P R ++RT P+P
Sbjct: 173 HFIKRLYQGQLPFPNHAEKQKQFEFVGSAP----TRRTKRTRRPQP 214
>gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
Length = 207
Score = 218 bits (554), Expect = 5e-57
Identities = 111/209 (53%), Positives = 143/209 (68%), Gaps = 18/209 (8%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLV 60
M S SA +CL LH L+LC Q Q L E FR HV Q+
Sbjct: 1 MYSAPSACTCLCLHFLLLCFQVQ-------VLVAEENVDFRI----------HVENQTRA 43
Query: 61 TDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGA 120
D +SR+ +R YQLYSRTSGKH+QVL +RI+A EDGD +A+L+VETDTFGS+VR++G
Sbjct: 44 RDDVSRKQLRLYQLYSRTSGKHIQVLG-RRISARGEDGDKYAQLLVETDTFGSQVRIKGK 102
Query: 121 ETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKG 180
ET Y+CMN+KGKL+ K +G K+CVF E VLENNYTAL +AKY GWY+ FT+KGRPRKG
Sbjct: 103 ETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKG 162
Query: 181 SKTRQHQREVHFMKRLPRGHHTTEQSLRF 209
KTR++Q++VHFMKR P+G ++ ++
Sbjct: 163 PKTRENQQDVHFMKRYPKGQPELQKPFKY 191
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 74.3 bits (181), Expect = 8e-14
Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 9/134 (6%)
Query: 68 LIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYIC 127
++R QLY RT G H+++ N I +D F L + G V +RG ++GLY+
Sbjct: 60 ILRRRQLYCRT-GFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGL-VSIRGVDSGLYLG 117
Query: 128 MNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEG------WYMAFTRKGRPRKGS 181
MN+KG+L S ++CVF E EN Y + Y+ +Y+A + G PR+G+
Sbjct: 118 MNEKGELYG-SEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGT 176
Query: 182 KTRQHQREVHFMKR 195
+T++HQ+ HF+ R
Sbjct: 177 RTKRHQKFTHFLPR 190
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 72.4 bits (176), Expect = 3e-13
Identities = 44/128 (34%), Positives = 73/128 (57%), Gaps = 4/128 (3%)
Query: 70 RTYQLYSRTS-GKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICM 128
R +LY G H+QVL + RI+ E+ +P++ L + T G V + G + L++ M
Sbjct: 84 RQRRLYCNVGIGFHLQVLPDGRISGTHEE-NPYSLLEISTVERGV-VSLFGVRSALFVAM 141
Query: 129 NKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQR 188
N KG+L A + + ++C F E +L NNY A ++ Y+G Y+A ++ GR ++GSK
Sbjct: 142 NSKGRLYATPSFQ-EECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIMT 200
Query: 189 EVHFMKRL 196
HF+ R+
Sbjct: 201 VTHFLPRI 208
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 71.6 bits (174), Expect = 5e-13
Identities = 43/134 (32%), Positives = 72/134 (53%), Gaps = 9/134 (6%)
Query: 68 LIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYIC 127
++R QLY RT G H+++ N ++ D F L + G + +RG ++GLY+
Sbjct: 59 ILRRRQLYCRT-GFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGL-ISIRGVDSGLYLG 116
Query: 128 MNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEG------WYMAFTRKGRPRKGS 181
MN++G+L S ++CVF E EN Y + Y+ +Y+A + G PR+G
Sbjct: 117 MNERGELYG-SKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGY 175
Query: 182 KTRQHQREVHFMKR 195
+T++HQ+ HF+ R
Sbjct: 176 RTKRHQKFTHFLPR 189
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 70.9 bits (172), Expect = 9e-13
Identities = 52/175 (29%), Positives = 85/175 (48%), Gaps = 21/175 (12%)
Query: 28 RGPALGRELASLFRAGREPQGVSQ-QHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVL 86
R P LG ++ R+ R G +Q H+ ++R QLY RT G H+Q+L
Sbjct: 33 RPPLLGERRSAAERSARGGPGAAQLAHLHG-----------ILRRRQLYCRT-GFHLQIL 80
Query: 87 ANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCV 146
+ + +D F L + G V +RG ++GLY+ MN KG+L S +C+
Sbjct: 81 PDGSVQGTRQDHSLFGILEFISVAVGL-VSIRGVDSGLYLGMNDKGELYG-SEKLTSECI 138
Query: 147 FTEIVLENNYTALQNAKYEG------WYMAFTRKGRPRKGSKTRQHQREVHFMKR 195
F E EN Y + Y+ +++A + G PR G+++++HQ+ HF+ R
Sbjct: 139 FREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPR 193
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 68.2 bits (165), Expect = 6e-12
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 73 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKG 132
+LY + G +++ + R++ + E DP KL ++ + G V ++G Y+ M + G
Sbjct: 164 RLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGV-VSIKGVCANRYLAMKEDG 222
Query: 133 KLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHF 192
+L+A S +C F E + NNY ++ KY WY+A R G+ + GSKT Q+ + F
Sbjct: 223 RLLA-SKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILF 281
Query: 193 M 193
+
Sbjct: 282 L 282
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 67.4 bits (163), Expect = 1e-11
Identities = 40/129 (31%), Positives = 71/129 (55%), Gaps = 7/129 (5%)
Query: 69 IRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICM 128
IR +L+ RT ++++ ++ E + + + + T G V ++G E+ Y+ M
Sbjct: 64 IRVRRLFCRTQW-YLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGI-VAIKGVESEFYLAM 121
Query: 129 NKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE----GWYMAFTRKGRPRKGSKTR 184
NK+GKL AK +DC F E++LEN+Y +AK+ ++A +KG P +G KT+
Sbjct: 122 NKEGKLYAKKE-CNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIPVRGKKTK 180
Query: 185 QHQREVHFM 193
+ Q+ HF+
Sbjct: 181 KEQKTAHFL 189
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 63.5 bits (153), Expect = 1e-10
Identities = 63/212 (29%), Positives = 92/212 (43%), Gaps = 22/212 (10%)
Query: 1 MGSPRSALSCLLLHLLVLCLQAQEGPGRGPA-----------LGRELASL--FRAGREPQ 47
M P +A LL +L+ L G G A L R SL R P
Sbjct: 1 MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV 60
Query: 48 GVSQQHVREQSLVTDQLSRRLIRTYQLYSRTS-GKHVQVLANKRIN-AMAEDGDPFAKLI 105
+ QS D L + R +LY G H+Q L + RI A A+ D +L
Sbjct: 61 AAQPKEAAVQSGAGDYLLG-IKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELS 119
Query: 106 -VETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY 164
VE V + G + ++ M+ KGKL S +C F EI+L NNY A ++ KY
Sbjct: 120 PVERGV----VSIFGVASRFFVAMSSKGKLYG-SPFFTDECTFKEILLPNNYNAYESYKY 174
Query: 165 EGWYMAFTRKGRPRKGSKTRQHQREVHFMKRL 196
G ++A ++ G+ +KG++ + HF+ RL
Sbjct: 175 PGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL 206
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 59.7 bits (143), Expect = 2e-09
Identities = 53/199 (26%), Positives = 86/199 (43%), Gaps = 22/199 (11%)
Query: 4 PRSALSCLLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQ-----QHVREQS 58
P C LL LV + P ALG+++ S S +HVR +
Sbjct: 17 PGCCCCCFLLLFLVSSV-----PVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYN 71
Query: 59 LVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVR 118
+ + R + ++ Y +++ N +++ ++ P++ L + + G V V+
Sbjct: 72 HLQGDVRWRKLFSFTKY------FLKIEKNGKVSGTKKENCPYSILEITSVEIGV-VAVK 124
Query: 119 GAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYT--ALQNAKYEG--WYMAFTRK 174
+ Y+ MNKKGKL S DC E + EN Y A N ++ G Y+A K
Sbjct: 125 AINSNYYLAMNKKGKLYG-SKEFNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGK 183
Query: 175 GRPRKGSKTRQHQREVHFM 193
G PR+G KTR+ HF+
Sbjct: 184 GAPRRGQKTRRKNTSAHFL 202
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 57.4 bits (137), Expect = 1e-08
Identities = 48/155 (30%), Positives = 70/155 (45%), Gaps = 24/155 (15%)
Query: 70 RTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVE-TDTFGSRVRVRGAETGLYICM 128
R +LY T H+Q+ + R+N E+ A I+E T V +RG +G Y+ M
Sbjct: 44 RRRKLYCATK-YHLQLHPSGRVNGSLENS---AYSILEITAVEVGIVAIRGLFSGRYLAM 99
Query: 129 NKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEG----------------WYMAFT 172
NK+G+L A S +C F E + E Y + Y WY++
Sbjct: 100 NKRGRLYA-SEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVN 158
Query: 173 RKGRPRKGSKTRQHQREVHFMKRL--PRGHHTTEQ 205
KGRPR+G KTR+ Q+ F+ R+ R H Q
Sbjct: 159 GKGRPRRGFKTRRTQKSSLFLPRVLDHRDHEMVRQ 193
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 55.1 bits (131), Expect = 5e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 73 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 131
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 53 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 109
Query: 132 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 185
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 110 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 168
Query: 186 HQREVHFMKR 195
++ HF+ +
Sbjct: 169 NKPAAHFLPK 178
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 55.1 bits (131), Expect = 5e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 73 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 131
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 53 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 109
Query: 132 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 185
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 110 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 168
Query: 186 HQREVHFMKR 195
++ HF+ +
Sbjct: 169 NKPAAHFLPK 178
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 55.1 bits (131), Expect = 5e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 73 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 131
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 82 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 138
Query: 132 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 185
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 139 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 197
Query: 186 HQREVHFMKR 195
++ HF+ +
Sbjct: 198 NKPAAHFLPK 207
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 55.1 bits (131), Expect = 5e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 73 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 131
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 26 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 82
Query: 132 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 185
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 83 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 141
Query: 186 HQREVHFMKR 195
++ HF+ +
Sbjct: 142 NKPAAHFLPK 151
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 55.1 bits (131), Expect = 5e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 73 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 131
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 72 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 128
Query: 132 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 185
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 129 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 187
Query: 186 HQREVHFMKR 195
++ HF+ +
Sbjct: 188 NKPAAHFLPK 197
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 55.1 bits (131), Expect = 5e-08
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 11/130 (8%)
Query: 73 QLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRV-RVRGAETGLYICMNKK 131
+LYSR G H+Q+ A+ I+ ++ + + G RV ++G +T LY+ MN +
Sbjct: 19 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 75
Query: 132 GKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWYMAFTRKGRPRKGSKTRQ 185
G L S +C F E V EN Y + Y GWY+ ++G KG+ ++
Sbjct: 76 GYLYT-SELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 134
Query: 186 HQREVHFMKR 195
++ HF+ +
Sbjct: 135 NKPAAHFLPK 144
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 74 LYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK 133
LY G +++L + ++ + D +L + ++ G V ++ ETG Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDG- 86
Query: 134 LIAKSNGKGKDCVFTEIVLENNYTALQNAKY--EGWYMAFTRKGRPRKGSKTRQHQREVH 191
L+ S ++C+F E + EN+Y + K+ + W++ + G ++G +T Q+ +
Sbjct: 87 LLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 192 FM 193
F+
Sbjct: 147 FL 148
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 74 LYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK 133
LY G +++L + ++ + D +L + ++ G V ++ ETG Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDG- 86
Query: 134 LIAKSNGKGKDCVFTEIVLENNYTALQNAKY--EGWYMAFTRKGRPRKGSKTRQHQREVH 191
L+ S ++C+F E + EN+Y + K+ + W++ + G ++G +T Q+ +
Sbjct: 87 LLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 192 FM 193
F+
Sbjct: 147 FL 148
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 74 LYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK 133
LY G +++L + ++ + D +L + ++ G V ++ ETG Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDG- 86
Query: 134 LIAKSNGKGKDCVFTEIVLENNYTALQNAKY--EGWYMAFTRKGRPRKGSKTRQHQREVH 191
L+ S ++C+F E + EN+Y + K+ + W++ + G ++G +T Q+ +
Sbjct: 87 LLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 192 FM 193
F+
Sbjct: 147 FL 148
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 53.5 bits (127), Expect = 1e-07
Identities = 29/122 (23%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Query: 74 LYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGK 133
LY G +++L + ++ + D +L + ++ G V ++ ETG Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDG- 86
Query: 134 LIAKSNGKGKDCVFTEIVLENNYTALQNAKY--EGWYMAFTRKGRPRKGSKTRQHQREVH 191
L+ S ++C+F E + EN+Y + K+ + W++ + G ++G +T Q+ +
Sbjct: 87 LLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 192 FM 193
F+
Sbjct: 147 FL 148
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 52.8 bits (125), Expect = 3e-07
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 21/152 (13%)
Query: 70 RTYQLYSRTS-GKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSR---VRVRGAETGLY 125
RT LY R G H+Q+ + ++N E A ++ + F V +RG + +
Sbjct: 87 RTGSLYCRVGIGFHLQIYPDGKVNGSHE-----ANMLSVLEIFAVSQGIVGIRGVFSNKF 141
Query: 126 ICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWYMAFTRKGRPRK 179
+ M+KKGKL A + DC F E EN+Y +A + WY+A ++G+ ++
Sbjct: 142 LAMSKKGKLHASAKFT-DDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKR 200
Query: 180 GSKTRQHQREV--HFMKRLPRGHHTTEQSLRF 209
G R + + HF LPR + + L F
Sbjct: 201 GCSPRVKPQHISTHF---LPRFKQSEQPELSF 229
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 48.9 bits (115), Expect = 4e-06
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 115 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWY 168
V ++G +TGLYI MN +G L S +C F E V EN Y + Y W+
Sbjct: 119 VAIQGVKTGLYIAMNGEGYLY-PSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 177
Query: 169 MAFTRKGRPRKGSKTRQHQREVHFMKR 195
+ ++G+ KG++ ++ + HF+ +
Sbjct: 178 LGLNKEGQAMKGNRVKKTKPAAHFLPK 204
>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
Length = 247
Score = 48.9 bits (115), Expect = 4e-06
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 7/87 (8%)
Query: 115 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY------EGWY 168
V ++G +TGLYI MN +G L S +C F E V EN Y + Y W+
Sbjct: 114 VAIQGVKTGLYIAMNGEGYLY-PSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWF 172
Query: 169 MAFTRKGRPRKGSKTRQHQREVHFMKR 195
+ ++G+ KG++ ++ + HF+ +
Sbjct: 173 LGLNKEGQAMKGNRVKKTKPAAHFLPK 199
>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
Length = 170
Score = 48.5 bits (114), Expect = 5e-06
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 5/83 (6%)
Query: 115 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY----EGWYMA 170
V ++ +G Y+ MN++G+L S DC F E + EN + + ++ + ++A
Sbjct: 84 VVIKAVSSGFYVAMNRRGRLYG-SRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLA 142
Query: 171 FTRKGRPRKGSKTRQHQREVHFM 193
R+G PR G +TR++ HF+
Sbjct: 143 LDRRGGPRPGGRTRRYHLSAHFL 165
>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
Length = 225
Score = 48.1 bits (113), Expect = 6e-06
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 7/88 (7%)
Query: 115 VRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYE------GWY 168
V ++ A+ G Y+ MN +G L + + +C F E V EN Y +A Y WY
Sbjct: 114 VTIQSAKLGHYMAMNAEGLLYSSPHFTA-ECRFKECVFENYYVLYASALYRQRRSGRAWY 172
Query: 169 MAFTRKGRPRKGSKTRQHQREVHFMKRL 196
+ ++G+ KG++ ++ + HF+ +L
Sbjct: 173 LGLDKEGQVMKGNRVKKTKAAAHFLPKL 200
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,222,765
Number of Sequences: 37866
Number of extensions: 394615
Number of successful extensions: 1006
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 948
Number of HSP's gapped (non-prelim): 45
length of query: 233
length of database: 18,247,518
effective HSP length: 99
effective length of query: 134
effective length of database: 14,498,784
effective search space: 1942837056
effective search space used: 1942837056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.