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Search of human proteins with 110225347
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform A [Homo
sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 864 0.0
gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ... 497 e-141
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 409 e-114
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 341 7e-94
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 341 9e-94
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 340 1e-93
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 332 5e-91
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 300 1e-81
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 293 2e-79
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 293 2e-79
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 293 2e-79
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 293 2e-79
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 293 2e-79
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 293 2e-79
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 293 2e-79
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 293 2e-79
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 293 2e-79
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 293 2e-79
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 293 2e-79
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 272 5e-73
gi|73858566 heparin cofactor II precursor [Homo sapiens] 210 2e-54
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 194 1e-49
gi|170295807 neuroserpin precursor [Homo sapiens] 193 2e-49
gi|4826904 neuroserpin precursor [Homo sapiens] 193 2e-49
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 191 1e-48
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 189 4e-48
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 186 3e-47
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 186 3e-47
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 186 3e-47
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 186 3e-47
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 864 bits (2232), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60
MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS
Sbjct: 1 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60
Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNL 120
QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNL
Sbjct: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNL 120
Query: 121 THTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFS 180
THTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFS
Sbjct: 121 THTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFS 180
Query: 181 TDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTR 240
TDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTR
Sbjct: 181 TDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTR 240
Query: 241 KNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQL 300
KNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQL
Sbjct: 241 KNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQL 300
Query: 301 EQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAK 360
EQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAK
Sbjct: 301 EQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAK 360
Query: 361 RDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKAT 420
RDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKAT
Sbjct: 361 RDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKAT 420
Query: 421 DGILFLGKVENPTKS 435
DGILFLGKVENPTKS
Sbjct: 421 DGILFLGKVENPTKS 435
>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
B [Homo sapiens]
Length = 335
Score = 497 bits (1279), Expect = e-141
Identities = 251/264 (95%), Positives = 252/264 (95%)
Query: 172 RLYEAEVFSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE 231
RLY V T N + ARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE
Sbjct: 72 RLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWE 131
Query: 232 KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL 291
KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL
Sbjct: 132 KPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL 191
Query: 292 PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK 351
PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK
Sbjct: 192 PSKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK 251
Query: 352 NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF 411
NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF
Sbjct: 252 NADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTF 311
Query: 412 LMMITNKATDGILFLGKVENPTKS 435
LMMITNKATDGILFLGKVENPTKS
Sbjct: 312 LMMITNKATDGILFLGKVENPTKS 335
Score = 191 bits (484), Expect = 1e-48
Identities = 95/116 (81%), Positives = 101/116 (87%), Gaps = 4/116 (3%)
Query: 1 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60
MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS
Sbjct: 1 MQGQGRRRGTCKDIFCSKMASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPAS 60
Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGL 116
QVYSLNTDFAFRLYRRLVLETPSQNIFFSP +++ + + G I+QGL
Sbjct: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQG----KVVDIIQGL 112
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 409 bits (1050), Expect = e-114
Identities = 211/417 (50%), Positives = 289/417 (69%), Gaps = 2/417 (0%)
Query: 19 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78
M+ +LY VL +GL A I+C SP +A SS + ++ S+N DFAF LYRR
Sbjct: 1 MSPFLYLVLLVLGLHATIHCASPEGKVTACH--SSQPNATLYKMSSINADFAFNLYRRFT 58
Query: 79 LETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHS 138
+ETP +NIFFSPVS+S +L MLS GA T+T+I++ LGFNLT TP I GFQHL+ S
Sbjct: 59 VETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICS 118
Query: 139 LTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVK 198
L P K+L L++G+ALF+ K L+ A FL +VK LYE EVFSTDFSN S A+ INSHV+
Sbjct: 119 LNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVE 178
Query: 199 KKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMM 258
+T+GKVV +IQ L T MVLVN+I FKA+W PF P T + FL+ + TV VPMM
Sbjct: 179 MQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMM 238
Query: 259 HQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQK 318
HQ EQ+ VD ELNC VLQMDY +A+A FVLP +G+M +E A+S++TL+KW+ LQK
Sbjct: 239 HQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQK 298
Query: 319 RWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVS 378
W+++F+P+FSISA+Y+L L KMGIQ+ + +NADFSG+ + + L++S A HKAVL +
Sbjct: 299 GWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIG 358
Query: 379 EEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS 435
E+GTEA A + + ++ + + +R+F+++I ++T ILFLGKV NPT++
Sbjct: 359 EKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA 415
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 341 bits (875), Expect = 7e-94
Identities = 183/385 (47%), Positives = 256/385 (66%), Gaps = 7/385 (1%)
Query: 55 KSTPASQVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQ 114
+ +P+ ++ N DFAFR Y + ETP +NIFFSP+S+S + AMLSLGA S +++QIL+
Sbjct: 44 EGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILE 103
Query: 115 GLGFNLTHTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLY 174
GLGFNLT ES +H+GFQHL+H+L +P L ++GSALF+ L+ A FL + +Y
Sbjct: 104 GLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVY 163
Query: 175 EAEVFSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPF 234
EA++F T+F + IN HVKK+T+GK+VD++ L MVLVN+I+FKA WEKPF
Sbjct: 164 EAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPF 223
Query: 235 HPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGV-DTELNCFVLQMDYKGDAVAFFVLPS 293
T F V E TV VPMM Q ++ + + D L C VL+MDYKGDA FF+LP+
Sbjct: 224 ISSRTTPK-DFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPN 282
Query: 294 KGKMRQLEQALSARTLRKWSHSLQKR----WIEVFIPRFSISASYNLETILPKMGIQNVF 349
+GKMR++E+ L+ L +W++ L+KR +E+ +P+FSIS SY L+ ILP++G ++F
Sbjct: 283 QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLF 342
Query: 350 DKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNR 409
K AD SGI K+ L+ SK+ HKA LDV E GTEA AAT+ S + + FNR
Sbjct: 343 SKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHI-LRFNR 401
Query: 410 TFLMMITNKATDGILFLGKVENPTK 434
FL++I + +T +LFLGKV +PTK
Sbjct: 402 PFLVVIFSTSTQSVLFLGKVVDPTK 426
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 341 bits (874), Expect = 9e-94
Identities = 184/413 (44%), Positives = 268/413 (64%), Gaps = 8/413 (1%)
Query: 27 LFAVGLCAPIYC---VSPANAPSAYPRPSSTK-STPASQVYSLN---TDFAFRLYRRLVL 79
L G+ A ++C ++ + P+P + S PA + + T+FA RLY+ L
Sbjct: 8 LLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKELAA 67
Query: 80 ETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSL 139
+ P NIFFSPVS+ST+LA+LSLGA + T IL+GLGFNLT TPE+ IHQGF+ L+H+L
Sbjct: 68 DAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHTL 126
Query: 140 TVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKK 199
+PS L LK+G++LF+ K L+ + ++L ++K LY A FS +F++ +IN ++++
Sbjct: 127 ALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRR 186
Query: 200 KTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMH 259
+T G+VVD + T MVL N+IFFKAKW+ PF T+K F V E+ ++ VPMMH
Sbjct: 187 QTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMH 246
Query: 260 QKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKR 319
QKE F D +L C VLQ++Y+G+A+A VLP GKM+Q+E AL +TLRKW L
Sbjct: 247 QKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLLLPS 306
Query: 320 WIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSE 379
+++ +PRFSIS +YNLE ILP++G+ N+ + ADFSG+ + + +SK +HKA++D+SE
Sbjct: 307 LLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSE 366
Query: 380 EGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432
+GTEA AA+ S + S FNR FL+++ T +LFLGKV NP
Sbjct: 367 KGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 340 bits (873), Expect = 1e-93
Identities = 189/413 (45%), Positives = 260/413 (62%), Gaps = 5/413 (1%)
Query: 27 LFAVGLCAPIYCV--SPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLVLETPSQ 84
L A G C + C SP + + + + S N DFAF LY++LVL+ P +
Sbjct: 12 LLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDK 71
Query: 85 NIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSLTVPSK 144
N+ FSP+S+ST+LA LSLGAH+ T T+IL+GL FNLT T E+ IHQ FQHL+ +L S
Sbjct: 72 NVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSD 131
Query: 145 DLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKTQGK 204
+L L MG+A+FVK++L L F + KRLY +E F+TDF + + A+ IN +VK T+GK
Sbjct: 132 ELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGK 191
Query: 205 VVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKE-Q 263
+ D+I+ LD T MVLVN+IFFKAKWE PF P+ T ++ F + ++ V VPMM
Sbjct: 192 ITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQS-RFYLSKKKWVMVPMMSLHHLT 250
Query: 264 FAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWI-E 322
+ D EL+C V+++ Y G+A A F+LP + KM ++E L TL++W SL+ R I E
Sbjct: 251 IPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGE 310
Query: 323 VFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGT 382
+++P+FSIS YNL IL ++GI+ F AD SGI +L VS+ HKAVLDV EEGT
Sbjct: 311 LYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGT 370
Query: 383 EATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS 435
EA+AAT K + S + V FNR FLM+I T I F+ KV NP ++
Sbjct: 371 EASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA 423
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 332 bits (850), Expect = 5e-91
Identities = 177/369 (47%), Positives = 243/369 (65%), Gaps = 5/369 (1%)
Query: 64 SLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHT 123
S DF F LYR L PSQ+IFFSPVS+S SLAMLSLGA S TK QIL+GLG NL +
Sbjct: 43 SSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKS 102
Query: 124 PESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDF 183
E +H+GFQ L+ L P L +G+ALF + LQ F+ +K LY A+ F T+F
Sbjct: 103 SEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF 162
Query: 184 SNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNF 243
+ + A +IN +V K+T+GK+VD+++ LD +++VN+IFFKAKWE F+ + T++
Sbjct: 163 RDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQ- 221
Query: 244 PFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQA 303
F V + V VPMM +++Q+ + +D L+C V+ + Y+G+A A F+LPS+GKM+Q+E
Sbjct: 222 DFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENG 281
Query: 304 LSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDS 363
LS +TLRKW +KR +E+++P+FSI SY LE +LP +GI NVF +AD SGI+ +
Sbjct: 282 LSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSN 341
Query: 364 LQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGI 423
+QVS+ HKAV++V E GT A AAT T F RS S V FNR FLM I + + I
Sbjct: 342 IQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNI 397
Query: 424 LFLGKVENP 432
LFLGKV P
Sbjct: 398 LFLGKVNRP 406
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 300 bits (769), Expect = 1e-81
Identities = 163/369 (44%), Positives = 226/369 (61%), Gaps = 5/369 (1%)
Query: 64 SLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHT 123
S N DFAF LY+ LV +P +NIF SPVS+S +LAMLSLG T+ Q+LQGLGFNLT
Sbjct: 41 SANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTER 100
Query: 124 PESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDF 183
E+ IHQGFQHL L + MG+ALF+ L+L +F ++K YE+EV + +F
Sbjct: 101 SETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNF 160
Query: 184 SNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNF 243
+ + A +INS+VK KTQGK+VD+ GLD +VLVN+IFFK W +PF TR+
Sbjct: 161 QDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREE- 219
Query: 244 PFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQA 303
F V E V VPMM Q ++ D EL C ++QM+Y G+ FF+LP KGKM + A
Sbjct: 220 NFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAA 279
Query: 304 LSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDS 363
LS T+ +WS L ++++IP+ +IS Y+L +L +MGI ++F A+FS I +
Sbjct: 280 LSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQ 339
Query: 364 LQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGI 423
L+ SK HKAVL ++EEG + +T + SK + FN+ F++MI + T
Sbjct: 340 LKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKP----IILRFNQPFIIMIFDHFTWSS 395
Query: 424 LFLGKVENP 432
LFL +V NP
Sbjct: 396 LFLARVMNP 404
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 293 bits (751), Expect = 2e-79
Identities = 167/420 (39%), Positives = 250/420 (59%), Gaps = 10/420 (2%)
Query: 20 ASYLYGVLFAVGLCA--PIYCVSPANAPSAYPRPSS--TKSTPASQVYSLN-TDFAFRLY 74
+S +G+L GLC P+ +A +S + P + N +FAF LY
Sbjct: 3 SSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLY 62
Query: 75 RRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQH 134
R+L ++ S NIFFSPVS++T+ AMLSLG + T +IL+GL FNLT PE+ IH+GFQ
Sbjct: 63 RQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQE 122
Query: 135 LVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARIN 194
L+ +L P L L G+ LF+ + L+L FL +VK+LY +E F+ +F + A+ +IN
Sbjct: 123 LLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQIN 182
Query: 195 SHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVH 254
+V+K TQGK+VD+++ LD T LVN+IFFK KWE+PF + T + F V + TV
Sbjct: 183 DYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEE-DFHVDQVTTVK 241
Query: 255 VPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSH 314
VPMM + F +L+ +VL M Y G+A A F LP +GK++ LE L+ + K+
Sbjct: 242 VPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLE 301
Query: 315 SLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAV 374
+ +R + +P+ SI+ +Y+L+++L ++GI VF AD SG+ + L++SKA HKAV
Sbjct: 302 NEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAV 361
Query: 375 LDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTK 434
L + E+GTEA A + I S V FN+ F+ ++ + T LF+GKV NPT+
Sbjct: 362 LTIDEKGTEAAGAMFLEAIPMSIPP----EVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 272 bits (695), Expect = 5e-73
Identities = 142/414 (34%), Positives = 238/414 (57%), Gaps = 9/414 (2%)
Query: 19 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78
+A +L +L GL P + SP N + + A ++ N D F+L ++L
Sbjct: 7 LAIFLAVLLTVKGLLKPSF--SPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLA 64
Query: 79 LETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHS 138
P +NIF SP+S+ST+ +ML LGA T +I QG FN PE +H+GF +++H
Sbjct: 65 FYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFRKMPEKDLHEGFHYIIHE 122
Query: 139 LTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVK 198
LT ++DL L +G+ LF+ + LQ Q FL + K Y AE T+F N +AQ +IN +
Sbjct: 123 LTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFIS 182
Query: 199 KKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMM 258
+KT GK+ ++I+ +D T M+L N+IFF+A+W+ F P T++ F + + +V VPMM
Sbjct: 183 QKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEE-DFFLEKNSSVKVPMM 241
Query: 259 HQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQK 318
+ + G D +L+C +L++ Y+ + A F+LP +GK++ LE+ L T +W L +
Sbjct: 242 FRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLSR 301
Query: 319 RWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVS 378
R ++V +PR ++ +++L+ L +G+ +F+++ D + IA SL+V +A HKA L +
Sbjct: 302 RVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMD 361
Query: 379 EEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432
E GTE A T + + + V ++ +L++I ++ +LFLGK+ NP
Sbjct: 362 ERGTEGAAGTGAQTLPME----TPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 210 bits (535), Expect = 2e-54
Identities = 134/378 (35%), Positives = 206/378 (54%), Gaps = 14/378 (3%)
Query: 65 LNTDFAFRLYRRLVLETPS-QNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGF----N 119
LN FAF LYR L + + NIF +PV +ST++ M+SLG T Q+ L F N
Sbjct: 129 LNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVN 188
Query: 120 LTHTPE-SAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEV 178
+ E + IH F+ L H L + TL+ + L+++K+ + +F V+ Y AE
Sbjct: 189 ASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEA 248
Query: 179 FSTDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEY 238
DFS+P+ ++ N+H+ K T+G + D ++ +D T M+++N I+FK W F E
Sbjct: 249 QIADFSDPAFI-SKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEM 307
Query: 239 TRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKM 297
T N F + E+ V V MM K F D EL+C +LQ++Y G V+P K M
Sbjct: 308 TH-NHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGM 366
Query: 298 RQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSG 357
+ LE L+ R + +W S+ R EV +P+F + +YNL L MGI+ +FDKN + +G
Sbjct: 367 KTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAG 426
Query: 358 IAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITN 417
I+ + + + H+ + V+EEGT+AT TT F+ S FTV +R FL +I
Sbjct: 427 ISDQ-RIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQ--VRFTV--DRPFLFLIYE 481
Query: 418 KATDGILFLGKVENPTKS 435
T +LF+G+V NP++S
Sbjct: 482 HRTSCLLFMGRVANPSRS 499
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 194 bits (493), Expect = 1e-49
Identities = 125/384 (32%), Positives = 207/384 (53%), Gaps = 19/384 (4%)
Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNL 120
Q+ S NT FA L+ L P+ NIF SP S+S+++AM+ LG T Q+ + FN
Sbjct: 3 QLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNT 62
Query: 121 THTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFS 180
+H FQ L + LK+ + L+ +K FL + ++ Y A++ S
Sbjct: 63 V----EEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLAS 118
Query: 181 TDFSNPS-IAQARINSHVKKKTQGKVVDIIQG--LDLLTAMVLVNHIFFKAKWEKPFHPE 237
DF + S A+ IN VK +T+GK+ +++ +D +T +VLVN I+FK W+ F E
Sbjct: 119 VDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKE 178
Query: 238 YTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL------ 291
T N PF + ++ V MM+QK++FA+G +L C VL++ Y+G+ ++ +L
Sbjct: 179 AT-TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE 237
Query: 292 PSKGKMRQLEQALSARTLRKWSHSLQKRWIE--VFIPRFSISASYNLETILPKMGIQNVF 349
++++E+ L+ L +W+ +IE V +PRF + SY L + L ++G+Q++F
Sbjct: 238 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF 297
Query: 350 DKN-ADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFN 408
+ + AD SG++ + +SK HK+ ++V+EEGTEA AAT FT +
Sbjct: 298 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTA--D 355
Query: 409 RTFLMMITNKATDGILFLGKVENP 432
FL I + ++ ILFLG+ +P
Sbjct: 356 HPFLFFIRHNSSGSILFLGRFSSP 379
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 193 bits (491), Expect = 2e-49
Identities = 113/376 (30%), Positives = 208/376 (55%), Gaps = 17/376 (4%)
Query: 68 DFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN-LTHTPES 126
D + +Y RL +NI FSP+S++ ++ M+ LGA T+ +I +G++ L + E
Sbjct: 28 DLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEF 87
Query: 127 AIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNP 186
+ + F ++V T +K+ ++LFV+ + FL +K+ + A V DFS
Sbjct: 88 SFLKEFSNMV---TAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQN 144
Query: 187 SIAQARINSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFP 244
IN V+ T V D++ + D T + L+N ++FK W+ F PE TR F
Sbjct: 145 VAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TFS 203
Query: 245 FLVGEQVTVHVPMMHQKEQFAFGVDTELN------CFVLQMDYKGDAVAFFVLPSKGK-- 296
F ++ V +PMM+Q+ +F +G ++ + VL++ Y+GD ++ ++ S+ +
Sbjct: 204 FTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVP 263
Query: 297 MRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFS 356
+ LE + A+ + +W++S++K+ +EV++PRF++ +L+ +L +GI +F K+A+ +
Sbjct: 264 LATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLT 323
Query: 357 GIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMIT 416
G++ + +SKA HK+ L+V+EEG+E AA + I S+ Y V + F +I
Sbjct: 324 GLSDNKEIFLSKAIHKSFLEVNEEGSE--AAAVSGMIAISRMAVLYPQVIVDHPFFFLIR 381
Query: 417 NKATDGILFLGKVENP 432
N+ T ILF+G+V +P
Sbjct: 382 NRRTGTILFMGRVMHP 397
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 193 bits (491), Expect = 2e-49
Identities = 113/376 (30%), Positives = 208/376 (55%), Gaps = 17/376 (4%)
Query: 68 DFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN-LTHTPES 126
D + +Y RL +NI FSP+S++ ++ M+ LGA T+ +I +G++ L + E
Sbjct: 28 DLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEF 87
Query: 127 AIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNP 186
+ + F ++V T +K+ ++LFV+ + FL +K+ + A V DFS
Sbjct: 88 SFLKEFSNMV---TAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQN 144
Query: 187 SIAQARINSHVKKKTQGKVVDII--QGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFP 244
IN V+ T V D++ + D T + L+N ++FK W+ F PE TR F
Sbjct: 145 VAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TFS 203
Query: 245 FLVGEQVTVHVPMMHQKEQFAFGVDTELN------CFVLQMDYKGDAVAFFVLPSKGK-- 296
F ++ V +PMM+Q+ +F +G ++ + VL++ Y+GD ++ ++ S+ +
Sbjct: 204 FTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVP 263
Query: 297 MRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFS 356
+ LE + A+ + +W++S++K+ +EV++PRF++ +L+ +L +GI +F K+A+ +
Sbjct: 264 LATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLT 323
Query: 357 GIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMIT 416
G++ + +SKA HK+ L+V+EEG+E AA + I S+ Y V + F +I
Sbjct: 324 GLSDNKEIFLSKAIHKSFLEVNEEGSE--AAAVSGMIAISRMAVLYPQVIVDHPFFFLIR 381
Query: 417 NKATDGILFLGKVENP 432
N+ T ILF+G+V +P
Sbjct: 382 NRRTGTILFMGRVMHP 397
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 191 bits (484), Expect = 1e-48
Identities = 124/375 (33%), Positives = 204/375 (54%), Gaps = 20/375 (5%)
Query: 69 FAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAI 128
FA RL + L + PS N+F SPVS+S++LAM+ LGA T TQ+ Q L N E I
Sbjct: 11 FAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN----TEEDI 66
Query: 129 HQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPS- 187
H+ FQ L+ + L+ + LF +K Q + F + + Y AE+ F +
Sbjct: 67 HRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAE 126
Query: 188 IAQARINSHVKKKTQGKVVDIIQG--LDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPF 245
++ IN+ V KKT+GK+ +++ G +D T +VLVN I+FK KW +PF YTR+ PF
Sbjct: 127 ESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTRE-MPF 185
Query: 246 LVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFV-LPSKG-KMRQLEQA 303
+ ++ V MM+Q+ F E+ +L++ Y ++ V LP G ++ +E++
Sbjct: 186 KINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKS 245
Query: 304 LSARTLRKWS--HSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK-NADFSGIAK 360
L+ L W+ ++ +EV +P+F + Y++E++L +GI + F + AD S ++
Sbjct: 246 LTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSA 305
Query: 361 RDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRS---KDGPSYFTVSFNRTFLMMITN 417
L +SK HK+ ++V+EEGTEA AA++ F+V + GP + + FL I +
Sbjct: 306 ERDLCLSKFVHKSFVEVNEEGTEAAAASSC-FVVAECCMESGPRFCA---DHPFLFFIRH 361
Query: 418 KATDGILFLGKVENP 432
+ ILF G+ +P
Sbjct: 362 NRANSILFCGRFSSP 376
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 189 bits (480), Expect = 4e-48
Identities = 128/388 (32%), Positives = 208/388 (53%), Gaps = 26/388 (6%)
Query: 66 NTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLT--HT 123
NT F F L+++ ++ NIF+SP+S++++L M+ LGA T QI + L F+ +T
Sbjct: 8 NTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENT 66
Query: 124 PESA----------IHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRL 173
E A +H FQ L+ + LK+ + LF +K Q +L +K+
Sbjct: 67 TEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKF 126
Query: 174 YEAEVFSTDFSN-PSIAQARINSHVKKKTQGKVVDIIQ----GLDLLTAMVLVNHIFFKA 228
Y+ V STDF+N P ++ +INS V+ +T K+ ++ G D T +VLVN I+FK
Sbjct: 127 YQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGND--TTLVLVNAIYFKG 184
Query: 229 KWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAF 288
+WE F E T++ F + V MM Q F F + ++ VL++ YKG ++
Sbjct: 185 QWENKFKKENTKEE-KFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSM 243
Query: 289 FVL-PSK-GKMRQLEQALSARTLRKWS--HSLQKRWIEVFIPRFSISASYNLETILPKMG 344
VL P++ +++LE+ L+A L +W+ ++++ +++ +PRF + SY+L+ L MG
Sbjct: 244 IVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMG 303
Query: 345 IQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFT 404
+ N+F+ +AD SG+ L VSK HKA ++V+EEG EA AAT +V +
Sbjct: 304 MVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAV-VVVELSSPSTNEE 362
Query: 405 VSFNRTFLMMITNKATDGILFLGKVENP 432
N FL I T+ ILF G+ +P
Sbjct: 363 FCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 186 bits (473), Expect = 3e-47
Identities = 125/411 (30%), Positives = 212/411 (51%), Gaps = 47/411 (11%)
Query: 66 NTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN------ 119
NT FA L++ L +P+QN+F SP S+S+++AM+ +G+ T+ Q+ + L FN
Sbjct: 8 NTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANA 67
Query: 120 -LTHTPES--------------------------AIHQGFQHLVHSLTVPSKDLTLKMGS 152
TPE+ IH F+ L ++ + + L+ +
Sbjct: 68 VTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN 127
Query: 153 ALFVKKELQLQANFLGNVKRLYEAEVFSTDFSN-PSIAQARINSHVKKKTQGKVVDIIQ- 210
LF +K + ++ ++ Y +E + DF A+ +INS VK +T+GK+ +++
Sbjct: 128 KLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPE 187
Query: 211 -GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVD 269
+D T MVLVN ++FK KW+ PF + +PF V V MM+ +E+ G
Sbjct: 188 GSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL-YPFRVNSAQRTPVQMMYLREKLNIGYI 246
Query: 270 TELNCFVLQMDYKGDAVAFFVLPSK-----GKMRQLEQALSARTLRKWS--HSLQKRWIE 322
+L +L++ Y GD F +LP + + LE ++ L KW+ + + +E
Sbjct: 247 EDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVE 306
Query: 323 VFIPRFSISASYNLETILPKMGIQNVFDK-NADFSGIAKRDSLQVSKATHKAVLDVSEEG 381
V+IP+F + Y L +IL MG+++ F+K A+FSG+++R+ L +S+ H+A++DV+EEG
Sbjct: 307 VYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEG 366
Query: 382 TEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432
TEA A T R+ G F + FL +I +K T+ ILF G+ +P
Sbjct: 367 TEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITNCILFFGRFSSP 415
>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 186 bits (473), Expect = 3e-47
Identities = 125/411 (30%), Positives = 212/411 (51%), Gaps = 47/411 (11%)
Query: 66 NTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN------ 119
NT FA L++ L +P+QN+F SP S+S+++AM+ +G+ T+ Q+ + L FN
Sbjct: 8 NTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANA 67
Query: 120 -LTHTPES--------------------------AIHQGFQHLVHSLTVPSKDLTLKMGS 152
TPE+ IH F+ L ++ + + L+ +
Sbjct: 68 VTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVN 127
Query: 153 ALFVKKELQLQANFLGNVKRLYEAEVFSTDFSN-PSIAQARINSHVKKKTQGKVVDIIQ- 210
LF +K + ++ ++ Y +E + DF A+ +INS VK +T+GK+ +++
Sbjct: 128 KLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPE 187
Query: 211 -GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVD 269
+D T MVLVN ++FK KW+ PF + +PF V V MM+ +E+ G
Sbjct: 188 GSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL-YPFRVNSAQRTPVQMMYLREKLNIGYI 246
Query: 270 TELNCFVLQMDYKGDAVAFFVLPSK-----GKMRQLEQALSARTLRKWS--HSLQKRWIE 322
+L +L++ Y GD F +LP + + LE ++ L KW+ + + +E
Sbjct: 247 EDLKAQILELPYAGDVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAEDEVE 306
Query: 323 VFIPRFSISASYNLETILPKMGIQNVFDK-NADFSGIAKRDSLQVSKATHKAVLDVSEEG 381
V+IP+F + Y L +IL MG+++ F+K A+FSG+++R+ L +S+ H+A++DV+EEG
Sbjct: 307 VYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEG 366
Query: 382 TEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432
TEA A T R+ G F + FL +I +K T+ ILF G+ +P
Sbjct: 367 TEAAAGTGGVMTGRTGHGGPQFVA--DHPFLFLIMHKITNCILFFGRFSSP 415
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 186 bits (473), Expect = 3e-47
Identities = 120/376 (31%), Positives = 197/376 (52%), Gaps = 10/376 (2%)
Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN- 119
Q+ ++F F L R++ + N+ FSP +S ++ L LGA T+TQI +GL
Sbjct: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132
Query: 120 LTHTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVF 179
L T + F+ L +L+ + +L L GS F+ K+ ++ F KR ++ E
Sbjct: 133 LKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECV 191
Query: 180 STDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYT 239
+F N S A+ +N ++ K+T+GK+ + ++ T ++LV++I FK KW PF P +T
Sbjct: 192 PMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFT 251
Query: 240 RKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMR 298
+ F + + T+ VPMM+ +FA D C VL++ Y+G+A VL K G
Sbjct: 252 EVD-TFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHL 310
Query: 299 QLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGI 358
LE L+ + W +++ R +EVF P+F + Y + +L +MGI+ +F AD S +
Sbjct: 311 ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSEL 370
Query: 359 -AKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITN 417
A +LQVS+ + V++V E GTEA A ++ S + +R F MI
Sbjct: 371 SATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP----VIKVDRPFHFMIYE 426
Query: 418 KATDGILFLGKVENPT 433
+ + +LFLG+V NPT
Sbjct: 427 ETSGMLLFLGRVVNPT 442
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 186 bits (473), Expect = 3e-47
Identities = 120/376 (31%), Positives = 197/376 (52%), Gaps = 10/376 (2%)
Query: 61 QVYSLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFN- 119
Q+ ++F F L R++ + N+ FSP +S ++ L LGA T+TQI +GL
Sbjct: 74 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 132
Query: 120 LTHTPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVF 179
L T + F+ L +L+ + +L L GS F+ K+ ++ F KR ++ E
Sbjct: 133 LKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECV 191
Query: 180 STDFSNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYT 239
+F N S A+ +N ++ K+T+GK+ + ++ T ++LV++I FK KW PF P +T
Sbjct: 192 PMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFT 251
Query: 240 RKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSK-GKMR 298
+ F + + T+ VPMM+ +FA D C VL++ Y+G+A VL K G
Sbjct: 252 EVD-TFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHL 310
Query: 299 QLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGI 358
LE L+ + W +++ R +EVF P+F + Y + +L +MGI+ +F AD S +
Sbjct: 311 ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSEL 370
Query: 359 -AKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITN 417
A +LQVS+ + V++V E GTEA A ++ S + +R F MI
Sbjct: 371 SATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPP----VIKVDRPFHFMIYE 426
Query: 418 KATDGILFLGKVENPT 433
+ + +LFLG+V NPT
Sbjct: 427 ETSGMLLFLGRVVNPT 442
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,231,358
Number of Sequences: 37866
Number of extensions: 642065
Number of successful extensions: 2000
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1740
Number of HSP's gapped (non-prelim): 71
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.