Search of human proteins with 14917115

Search of human proteins with 14917115

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14917115 keratin 31 [Homo sapiens]
         (416 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14917115 keratin 31 [Homo sapiens]                                 842   0.0  
gi|10337581 type I hair keratin 3B [Homo sapiens]                     755   0.0  
gi|14917117 keratin 33A [Homo sapiens]                                750   0.0  
gi|14917119 keratin 34 [Homo sapiens]                                 692   0.0  
gi|94538345 keratin 35 [Homo sapiens]                                 562   e-160
gi|4504927 keratin 36 [Homo sapiens]                                  551   e-157
gi|116488398 keratin 32 [Homo sapiens]                                550   e-156
gi|15431318 keratin 38 [Homo sapiens]                                 495   e-140
gi|125490370 type I hair keratin KA36 [Homo sapiens]                  478   e-135
gi|55770882 keratin 37 [Homo sapiens]                                 476   e-134
gi|148277620 type I hair keratin KA35 [Homo sapiens]                  462   e-130
gi|15431310 keratin 14 [Homo sapiens]                                 382   e-106
gi|24430192 keratin 16 [Homo sapiens]                                 375   e-104
gi|4557701 keratin 17 [Homo sapiens]                                  373   e-103
gi|24234699 keratin 19 [Homo sapiens]                                 360   1e-99
gi|24430190 keratin 15 [Homo sapiens]                                 360   1e-99
gi|131412225 keratin 13 isoform a [Homo sapiens]                      352   5e-97
gi|131412228 keratin 13 isoform b [Homo sapiens]                      351   8e-97
gi|195972866 keratin 10 [Homo sapiens]                                333   2e-91
gi|4557699 keratin 12 [Homo sapiens]                                  330   2e-90
gi|27894337 keratin 20 [Homo sapiens]                                 312   4e-85
gi|153945736 keratin 27 [Homo sapiens]                                300   2e-81
gi|192807292 keratin 24 [Homo sapiens]                                297   1e-80
gi|114431246 keratin 25D [Homo sapiens]                               297   1e-80
gi|40354195 keratin 18 [Homo sapiens]                                 293   2e-79
gi|4557888 keratin 18 [Homo sapiens]                                  293   2e-79
gi|31559829 keratin 25 [Homo sapiens]                                 291   7e-79
gi|55956899 keratin 9 [Homo sapiens]                                  270   2e-72
gi|27894339 keratin 23 [Homo sapiens]                                 267   2e-71
gi|31559815 keratin 26 [Homo sapiens]                                 267   2e-71

>gi|14917115 keratin 31 [Homo sapiens]
          Length = 416

 Score =  842 bits (2174), Expect = 0.0
 Identities = 416/416 (100%), Positives = 416/416 (100%)

Query: 1   MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60
           MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETM
Sbjct: 1   MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCT 120
           QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCT
Sbjct: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCT 120

Query: 121 KSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQV 180
           KSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQV
Sbjct: 121 KSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQV 180

Query: 181 ESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNR 240
           ESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNR
Sbjct: 181 ESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNR 240

Query: 241 REVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300
           REVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL
Sbjct: 241 REVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300

Query: 301 TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360
           TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL
Sbjct: 301 TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360

Query: 361 ESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSFVR 416
           ESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSFVR
Sbjct: 361 ESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSFVR 416


>gi|10337581 type I hair keratin 3B [Homo sapiens]
          Length = 404

 Score =  755 bits (1949), Expect = 0.0
 Identities = 380/414 (91%), Positives = 388/414 (93%), Gaps = 12/414 (2%)

Query: 1   MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60
           MPYNFCLPSLSCRTSCSSRPCVPPSCH  TLPGACNIPANVSNCNWFCEGSFNGSEKETM
Sbjct: 1   MPYNFCLPSLSCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCT 120
           QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILC+
Sbjct: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCS 120

Query: 121 KSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQV 180
           KSENARLVVQIDNAKLAADDFRTKYQTE SLRQLVESDIN LRRILDELTLC+SDLEAQ+
Sbjct: 121 KSENARLVVQIDNAKLAADDFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQM 180

Query: 181 ESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNR 240
           ESLKEELL LK NHEQEVNTLRCQLGDRLNVEVDAAP VDLN+VLNETR+QYEALVETNR
Sbjct: 181 ESLKEELLSLKQNHEQEVNTLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNR 240

Query: 241 REVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300
           REVEQWF TQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR SLENTL
Sbjct: 241 REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTL 300

Query: 301 TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360
           TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL
Sbjct: 301 TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360

Query: 361 ESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSF 414
           ESEDC LPSNPCATTNAC KPIG C++N            PC PR RCGPCN+F
Sbjct: 361 ESEDCKLPSNPCATTNACEKPIGSCVTN------------PCGPRSRCGPCNTF 402


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score =  750 bits (1936), Expect = 0.0
 Identities = 378/414 (91%), Positives = 387/414 (93%), Gaps = 12/414 (2%)

Query: 1   MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60
           M Y+  LPSLSCRTSCSSRPCVPPSCH CTLPGACNIPANVSNCNWFCEGSFNGSEKETM
Sbjct: 1   MSYSCGLPSLSCRTSCSSRPCVPPSCHGCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCT 120
           QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPL+C SYQSYFKTIEELQQKILC+
Sbjct: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCS 120

Query: 121 KSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQV 180
           KSENARLVVQIDNAKLA+DDFRTKY+TELSLRQLVESDINGLRRILDELTLC+SDLEAQV
Sbjct: 121 KSENARLVVQIDNAKLASDDFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQV 180

Query: 181 ESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNR 240
           ESLKEELLCLK NHEQEVNTLRCQLGDRLNVEVDAAPTVDLN+VLNETRSQYEALVETNR
Sbjct: 181 ESLKEELLCLKQNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNR 240

Query: 241 REVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300
           REVEQWF TQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL
Sbjct: 241 REVEQWFATQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300

Query: 301 TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360
           TESEARYSSQLSQVQ LITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL
Sbjct: 301 TESEARYSSQLSQVQRLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360

Query: 361 ESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNSF 414
           ESEDC LPSNPCATTNAC K  GPC+SN            PC  R RCGPCN+F
Sbjct: 361 ESEDCKLPSNPCATTNACDKSTGPCISN------------PCGLRARCGPCNTF 402


>gi|14917119 keratin 34 [Homo sapiens]
          Length = 436

 Score =  692 bits (1786), Expect = 0.0
 Identities = 348/385 (90%), Positives = 359/385 (93%)

Query: 1   MPYNFCLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETM 60
           M Y+ CLPSL CRTSCSSRPCVPPSCH  TLPGACNIPANVSNCNWFCEGSFNGSEKETM
Sbjct: 43  MSYSCCLPSLGCRTSCSSRPCVPPSCHGYTLPGACNIPANVSNCNWFCEGSFNGSEKETM 102

Query: 61  QFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCT 120
           QFLNDRLASYLEKVRQLERDNAELE LI+ERSQQQEPLLCPSYQSYFKTIEELQQKILC 
Sbjct: 103 QFLNDRLASYLEKVRQLERDNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCA 162

Query: 121 KSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQV 180
           K+ENARLVV IDNAKLA+DDFR+KYQTE SLR LVESDIN +RRILDELTLCKSDLE+QV
Sbjct: 163 KAENARLVVNIDNAKLASDDFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQV 222

Query: 181 ESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNR 240
           ESL+EEL+CLK NHE+EVNTLR QLGDRLNVEVD APTVDLN+VLNETRSQYEALVE NR
Sbjct: 223 ESLREELICLKKNHEEEVNTLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINR 282

Query: 241 REVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTL 300
           REVEQWF TQTEELNKQVVSSSEQLQS QAEIIELRRTVNALEIELQAQHNLRDSLENTL
Sbjct: 283 REVEQWFATQTEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTL 342

Query: 301 TESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLL 360
           TESEA YSSQLSQVQSLITNVESQLAEIR DLERQNQEYQVLLDVRARLECEINTYRSLL
Sbjct: 343 TESEAHYSSQLSQVQSLITNVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLL 402

Query: 361 ESEDCNLPSNPCATTNACSKPIGPC 385
           ESEDC LP NPCATTNA     GPC
Sbjct: 403 ESEDCKLPCNPCATTNASGNSCGPC 427


>gi|94538345 keratin 35 [Homo sapiens]
          Length = 455

 Score =  562 bits (1449), Expect = e-160
 Identities = 292/399 (73%), Positives = 327/399 (81%), Gaps = 6/399 (1%)

Query: 13  RTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLE 72
           R+S  +  C+P  C    LP      +      WF EG   G+EKETMQ LNDRLA YLE
Sbjct: 58  RSSYRATSCLPALC----LPAGGFATSYSGGGGWFGEGILTGNEKETMQSLNDRLAGYLE 113

Query: 73  KVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQID 132
           KVRQLE++NA LE+ IRE  +QQ P +CP YQSYF+TIEELQ+K LC+K+ENARLVV+ID
Sbjct: 114 KVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEID 173

Query: 133 NAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKS 192
           NAKLAADDFRTKY+TE+SLRQLVESDINGLRRILD+LTLCKSDLEAQVESLKEELLCLK 
Sbjct: 174 NAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKK 233

Query: 193 NHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTE 252
           NHE+EVN+LRCQLGDRLNVEVDAAP VDLNRVL E R QYE LVE NRR+ E W  TQ+E
Sbjct: 234 NHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSE 293

Query: 253 ELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLS 312
           ELN+QVVSSSEQLQS QAEIIELRRTVNALEIELQAQH++RD+LE+TL E+EARYSSQL+
Sbjct: 294 ELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLA 353

Query: 313 QVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPC 372
           Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRARLECEINTYR LLESED  LP NPC
Sbjct: 354 QMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPC 413

Query: 373 ATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPC 411
           A   + SK   PCL  P  SC P A  T C+PRP C PC
Sbjct: 414 APDYSPSKSCLPCL--PAASCGPSAARTNCSPRPICVPC 450


>gi|4504927 keratin 36 [Homo sapiens]
          Length = 467

 Score =  551 bits (1420), Expect = e-157
 Identities = 287/381 (75%), Positives = 321/381 (84%), Gaps = 7/381 (1%)

Query: 21  CVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERD 80
           C+P S     L   C+    V +  WFCEGSFNGSEKETMQFLNDRLA+YLEKVRQLER+
Sbjct: 62  CLPGSY----LSSECHTSGFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERE 117

Query: 81  NAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADD 140
           NAELE+ I+E  + Q P +CP YQSYFKTIE+ QQKIL TKSENARLV+QIDNAKLAADD
Sbjct: 118 NAELESRIQEWYEFQIPYICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADD 177

Query: 141 FRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNT 200
           FRTKY+TELSLRQLVE+DINGLRRILDELTLCK+DLEAQVESLKEEL+CLK NHE+EV+ 
Sbjct: 178 FRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSV 237

Query: 201 LRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVS 260
           LRCQLGDRLNVEVDAAP VDLN++L + R QYEALVE NRR+VE WF TQTEELN+QVVS
Sbjct: 238 LRCQLGDRLNVEVDAAPPVDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVS 297

Query: 261 SSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITN 320
           SSEQLQ  Q EIIELRRTVNALEIELQAQH++R+SLE+TL E+EARYSSQL+Q+Q LI+N
Sbjct: 298 SSEQLQCCQTEIIELRRTVNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISN 357

Query: 321 VESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSK 380
           VE+QL+EIR DLERQNQEYQVLLDV+ARLE EI TYR LLE EDC LP  PCAT  AC K
Sbjct: 358 VEAQLSEIRCDLERQNQEYQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCAT--AC-K 414

Query: 381 PIGPCLSNPCTSCVPPAPCTP 401
           P+    S P   CVP  PCTP
Sbjct: 415 PVIRVPSVPPVPCVPSVPCTP 435


>gi|116488398 keratin 32 [Homo sapiens]
          Length = 448

 Score =  550 bits (1416), Expect = e-156
 Identities = 278/402 (69%), Positives = 331/402 (82%), Gaps = 2/402 (0%)

Query: 6   CLPSLSCRTSCSSRPCVPPSCHSCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLND 65
           CLPS+   T+     C+  +  S +   A  I  ++   +W+ EG+FNG+EKETMQFLND
Sbjct: 46  CLPSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLND 105

Query: 66  RLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENA 125
           RLASYL +VRQLE++NAELE+ I+E S  Q   + P YQS+F+TIEELQQKILCTK+ENA
Sbjct: 106 RLASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENA 165

Query: 126 RLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKE 185
           R+VV IDNAKLAADDFR KY+ EL++RQLVE+DINGLRRILD+LTLCK+DLEAQVESLKE
Sbjct: 166 RMVVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKE 225

Query: 186 ELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQ 245
           EL+CLK NHE+EV +LRCQLGDRLN+EVDAAP VDL RVL E R QYEA+VE NRR+VE+
Sbjct: 226 ELMCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEE 285

Query: 246 WFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEA 305
           WF  Q EELN+QV +SSEQLQ+YQ++II+LRRTVN LEIELQAQH+LRDSLENTLTESEA
Sbjct: 286 WFNMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEA 345

Query: 306 RYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDC 365
           RYSSQL+Q+Q +ITNVE+QLAEIR+DLERQNQEYQVLLDVRARLE EINTYRSLLE+EDC
Sbjct: 346 RYSSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDC 405

Query: 366 NLPSNPCATTNACSKPIGPCLSNPCTSCVPPAPCTPCAPRPR 407
            LP NPC+T +  +    PC+  P T CVP     PC+P P+
Sbjct: 406 KLPCNPCSTPSCTTCVPSPCV--PRTVCVPRTVGMPCSPCPQ 445


>gi|15431318 keratin 38 [Homo sapiens]
          Length = 456

 Score =  495 bits (1274), Expect = e-140
 Identities = 248/394 (62%), Positives = 308/394 (78%), Gaps = 20/394 (5%)

Query: 21  CVPPSCHS-CTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
           C+PP+CH+ C LPG C+IP N+  C  + E + NG EKETMQFLNDRLA+YLEKVRQLE+
Sbjct: 68  CLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLEKVRQLEQ 127

Query: 80  DNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAAD 139
           +NAELE  + ERS+  E  +CP YQSYF TIEELQQKILC+K+ENARL+VQIDNAKLAAD
Sbjct: 128 ENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQIDNAKLAAD 187

Query: 140 DFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVN 199
           DFR K ++E SLRQLVE+D  G +++LD+ TL K+DLEAQ ESLKEE L LKSNHEQEV 
Sbjct: 188 DFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247

Query: 200 TLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVV 259
            LR QLG++L +E+D  PT+DLNRVL E R+QYEA++ETNR++VEQWF  Q+E ++ Q +
Sbjct: 248 ILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSEGISLQDM 307

Query: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLIT 319
           S SE+LQ  Q+EI+ELR TVNALE+E QAQH L+D L+N+L E+E R+ ++L+Q+QSLI+
Sbjct: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELAQMQSLIS 367

Query: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACS 379
           NVE QL+EIR+DLERQNQEYQVLLDV+ RLE EI TYR+LLESEDC LP NPC+T+ +C 
Sbjct: 368 NVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPCSTSPSC- 426

Query: 380 KPIGPCLSNPCTSCVPPAPCTPCAPRPRCGPCNS 413
                                PCAPRP CGPC +
Sbjct: 427 ------------------VTAPCAPRPSCGPCTT 442


>gi|125490370 type I hair keratin KA36 [Homo sapiens]
          Length = 431

 Score =  478 bits (1231), Expect = e-135
 Identities = 248/398 (62%), Positives = 300/398 (75%), Gaps = 18/398 (4%)

Query: 6   CLPSLSC--RTSCSSRPCVPPSCHS------------CTLP----GACNIPANVSNCNWF 47
           C P+ SC   T+C    C    C +            C LP    G+CN P  V NC W 
Sbjct: 21  CAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWC 80

Query: 48  CEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYF 107
            +G F  +EKETMQFLNDRLASYLEKVR LE  NAELE+ I+E+ +Q  P++CP YQ YF
Sbjct: 81  EDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYF 140

Query: 108 KTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILD 167
            TIE+LQQKILCTK+EN+RL VQ+DN KLA DDF++KY++ELSLRQL+E+DI+ L  IL+
Sbjct: 141 NTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILE 200

Query: 168 ELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNE 227
           ELTLCKSDLEA VESLKE+LLCLK NHE+EVN LR QLGDRL+VE+D APT+DLNRVL+E
Sbjct: 201 ELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDE 260

Query: 228 TRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQ 287
            R Q E ++  NRRE E+W   QTEELN+Q +SS+EQLQ  Q EI+EL+RT +ALEIELQ
Sbjct: 261 MRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQ 320

Query: 288 AQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRA 347
           AQ +L +SLE T+ E+EA+YSSQL+Q+Q LI N+E+QLAEIR DLERQNQEYQVLLDV+A
Sbjct: 321 AQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKA 380

Query: 348 RLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPC 385
           RLE EINTY  LL+SED  L  +PC+TT   S    PC
Sbjct: 381 RLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPC 418


>gi|55770882 keratin 37 [Homo sapiens]
          Length = 449

 Score =  476 bits (1226), Expect = e-134
 Identities = 239/382 (62%), Positives = 301/382 (78%), Gaps = 10/382 (2%)

Query: 21  CVPPSCHS-CTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
           C+PP+ H+ C LPG C+IP N+  C  + + + NG EKETM+FLNDRLA+YLEKVRQLE+
Sbjct: 68  CLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQ 127

Query: 80  DNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAAD 139
           +NAELE  + ERS+  E  +CP YQSYF+TIEELQQKILC+K+ENARL+VQIDNAKLAAD
Sbjct: 128 ENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAAD 187

Query: 140 DFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVN 199
           DFR K ++E SL QLVE+D  G +++LD+ TL K+DLEAQ ESLKEE L LKSNHEQEV 
Sbjct: 188 DFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247

Query: 200 TLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVV 259
            LR QLG++  +E+D  PT+DLNRVL E R+QYEA+VETN ++VEQWF  Q+E ++ Q +
Sbjct: 248 ILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAM 307

Query: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLIT 319
           S SE+LQ  Q+EI+ELR TVNALE+E QAQH L+D L+N+L E+E RY ++L+Q+QSLI+
Sbjct: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLIS 367

Query: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACS 379
           N+E QL+EIR+DLERQNQEYQVLLDV+ARLE EI TYR+LLESEDC LP NPC+T  +C+
Sbjct: 368 NLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPASCT 427

Query: 380 KPIGPCLSNPCTSCVPPAPCTP 401
                     C SC P    +P
Sbjct: 428 S---------CPSCGPVTGGSP 440


>gi|148277620 type I hair keratin KA35 [Homo sapiens]
          Length = 491

 Score =  462 bits (1189), Expect = e-130
 Identities = 238/382 (62%), Positives = 298/382 (78%), Gaps = 3/382 (0%)

Query: 36  NIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQ 95
           N   ++ +C+W+ EG  N +EKETMQ LN+RLA+YL+KVR LER+NAELE+ I+E S ++
Sbjct: 77  NARFSLDDCSWYGEG-INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKE 135

Query: 96  EPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLV 155
            P+LCP Y SY+ TIEELQQKILCTK+EN+RLV QIDN KL ADD R KY+ E+SLRQLV
Sbjct: 136 LPVLCPDYLSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLV 195

Query: 156 ESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDA 215
           ESD NGL++IL+ LTL K+DLEAQV+SLKEELLCLK+NH++E+N+L+CQLG+RL++EV A
Sbjct: 196 ESDANGLKQILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTA 255

Query: 216 APTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIEL 275
           AP+ DLN+VL E R QYE ++ETNR++VEQWF TQ EELN+QVV+SS+Q Q  Q EIIEL
Sbjct: 256 APSADLNQVLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIEL 315

Query: 276 RRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQ 335
           RR+VN LE+ELQAQH +RDS E  LTE+EARY++ L+Q+QSLI N+E+QLAEIR  LERQ
Sbjct: 316 RRSVNTLEVELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQ 375

Query: 336 NQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCVP 395
           NQEY++LLDV++RLECEI TYRSLLES D   P  P AT    S P   C S    S  P
Sbjct: 376 NQEYEILLDVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPS-PWTSCKSGAIESTAP 434

Query: 396 P-APCTPCAPRPRCGPCNSFVR 416
                +PC+ +  C  C    R
Sbjct: 435 ACTSSSPCSLKEHCSACGPLSR 456


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score =  382 bits (981), Expect = e-106
 Identities = 195/334 (58%), Positives = 260/334 (77%)

Query: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 108 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPAEIKDYSPYFK 167

Query: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168
           TIE+L+ KIL    +NA +++QIDNA+LAADDFRTKY+TEL+LR  VE+DINGLRR+LDE
Sbjct: 168 TIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEADINGLRRVLDE 227

Query: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228
           LTL ++DLE Q+ESLKEEL  LK NHE+E+N LR Q+G  +NVE+DAAP VDL+R+LNE 
Sbjct: 228 LTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPGVDLSRILNEM 287

Query: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R QYE + E NR++ E+WF T+TEELN++V ++SE +QS ++EI ELRRT+  LEIELQ+
Sbjct: 288 RDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRTMQNLEIELQS 347

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++ SLEN+L E++ RY  QL+Q+Q +I +VE QLA++R ++E+QNQEY++LLDV+ R
Sbjct: 348 QLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 407

Query: 349 LECEINTYRSLLESEDCNLPSNPCATTNACSKPI 382
           LE EI TYR LLE ED +L S+  ++ +  S+ +
Sbjct: 408 LEQEIATYRRLLEGEDAHLSSSQFSSGSQSSRDV 441


>gi|24430192 keratin 16 [Homo sapiens]
          Length = 473

 Score =  375 bits (964), Expect = e-104
 Identities = 193/334 (57%), Positives = 253/334 (75%)

Query: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108
           +G   GSEK TMQ LNDRLASYL+KVR LE  NA+LE  IR+  Q+Q P     Y  YFK
Sbjct: 110 DGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSPYFK 169

Query: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168
           TIE+L+ KI+    ENA+ ++QIDNA+LAADDFRTKY+ EL+LRQ VE+D+NGLRR+LDE
Sbjct: 170 TIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRVLDE 229

Query: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228
           LTL ++DLE Q+E LKEEL  L+ NHE+E+  LR Q G  +NVE+DAAP VDL+R+LNE 
Sbjct: 230 LTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRILNEM 289

Query: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R QYE + E NRR+ E WF ++TEELNK+V S+SE +QS ++E+ ELRR +  LEIELQ+
Sbjct: 290 RDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIELQS 349

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++ SLEN+L E++ RY  QLSQ+Q LI +VE QLA++R ++E+Q+QEYQ+LLDV+ R
Sbjct: 350 QLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDVKTR 409

Query: 349 LECEINTYRSLLESEDCNLPSNPCATTNACSKPI 382
           LE EI TYR LLE ED +L S   +  +  S+ +
Sbjct: 410 LEQEIATYRRLLEGEDAHLSSQQASGQSYSSREV 443


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score =  373 bits (957), Expect = e-103
 Identities = 191/319 (59%), Positives = 247/319 (77%)

Query: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108
           +G   G EK TMQ LNDRLASYL+KVR LE  N ELE  IR+  Q+Q P     Y  Y++
Sbjct: 77  DGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQAPGPARDYSQYYR 136

Query: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168
           TIEELQ KIL    +NA +++QIDNA+LAADDFRTK++TE +LR  VE+DINGLRR+LDE
Sbjct: 137 TIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVEADINGLRRVLDE 196

Query: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228
           LTL ++DLE Q+E+LKEEL  LK NHE+E+N LR Q+G  +NVE+DAAP VDL+R+LNE 
Sbjct: 197 LTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILNEM 256

Query: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R QYE + E NR++ E WF ++TEELN++V ++SE +QS ++EI ELRRT+ ALEIELQ+
Sbjct: 257 RDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQS 316

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++ SLE  L E+E RY  QLSQ+Q LI +VE QLA++R ++E+QNQEY++LLDV+ R
Sbjct: 317 QLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTR 376

Query: 349 LECEINTYRSLLESEDCNL 367
           LE EI TYR LLE ED +L
Sbjct: 377 LEQEIATYRRLLEGEDAHL 395


>gi|24234699 keratin 19 [Homo sapiens]
          Length = 400

 Score =  360 bits (925), Expect = 1e-99
 Identities = 179/316 (56%), Positives = 249/316 (78%)

Query: 49  EGSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFK 108
           +G   G+EK TMQ LNDRLASYL+KVR LE  N ELE  IR+  Q+Q P     Y  Y+ 
Sbjct: 73  DGLLAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYT 132

Query: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168
           TI++L+ KIL    EN+R+V+QIDNA+LAADDFRTK++TE +LR  VE+DINGLRR+LDE
Sbjct: 133 TIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDE 192

Query: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228
           LTL ++DLE Q+E LKEEL  LK NHE+E++TLR Q+G +++VEVD+AP  DL ++L++ 
Sbjct: 193 LTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDM 252

Query: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           RSQYE + E NR++ E WFT++TEELN++V   +EQLQ  ++E+ +LRRT+  LEIELQ+
Sbjct: 253 RSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQS 312

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++ +LE+TL E+EAR+ +QL+ +Q+LI+ +E+QL ++R+D ERQNQEYQ L+D+++R
Sbjct: 313 QLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSR 372

Query: 349 LECEINTYRSLLESED 364
           LE EI TYRSLLE ++
Sbjct: 373 LEQEIATYRSLLEGQE 388


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score =  360 bits (925), Expect = 1e-99
 Identities = 184/319 (57%), Positives = 244/319 (76%), Gaps = 1/319 (0%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCP-SYQSYFK 108
           G  +G+EK TMQ LNDRLASYL+KVR LE  NA+LE  I +  Q+Q P      Y  YFK
Sbjct: 99  GLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPTSPECDYSQYFK 158

Query: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168
           TIEEL+ KI+ T  +N+R++++IDNA+LAADDFR KY+ EL+LRQ VE+DINGLRR+LDE
Sbjct: 159 TIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVEADINGLRRVLDE 218

Query: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228
           LTL ++DLE Q+E L EEL  LK NHE+E+     QL  ++NVE+DAAP VDL RVL E 
Sbjct: 219 LTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAAPGVDLTRVLAEM 278

Query: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R QYEA+ E NRR+VE WF ++TEELNK+V S++E +Q+ + EI +LRRT+  LEIELQ+
Sbjct: 279 REQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLRRTMQELEIELQS 338

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q +++  LEN+L E+E RY++QL Q+Q LI  +E+QL+E+R ++E QNQEY++LLD++ R
Sbjct: 339 QLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQNQEYKMLLDIKTR 398

Query: 349 LECEINTYRSLLESEDCNL 367
           LE EI TYRSLLE +D  +
Sbjct: 399 LEQEIATYRSLLEGQDAKM 417


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score =  352 bits (902), Expect = 5e-97
 Identities = 182/326 (55%), Positives = 243/326 (74%), Gaps = 2/326 (0%)

Query: 48  CEGSF-NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCP-SYQS 105
           C+G    G+EK TMQ LNDRLASYLEKVR LE  NA+LE  IR+   +Q P      Y  
Sbjct: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154

Query: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165
           Y+KTIEEL+ KIL    EN R++++IDNA+LAADDFR KY+ EL+LRQ VE+DINGLRR+
Sbjct: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214

Query: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225
           LDELTL K+DLE Q+ESL EEL  +K NHE+E+     Q+  ++NVE+DA P +DL RVL
Sbjct: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274

Query: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
            E R QYEA+ E NRR+ E+WF  ++ ELNK+V +++  +Q+ + EI ELRRT+  LEIE
Sbjct: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+Q +++  LENT+ E+E RY+ QL Q+Q LI+++E+QL+E+RS++E QNQEY++LLD+
Sbjct: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394

Query: 346 RARLECEINTYRSLLESEDCNLPSNP 371
           + RLE EI TYRSLLE +D  +   P
Sbjct: 395 KTRLEQEIATYRSLLEGQDAKMIGFP 420


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score =  351 bits (900), Expect = 8e-97
 Identities = 182/326 (55%), Positives = 242/326 (74%), Gaps = 2/326 (0%)

Query: 48  CEGSF-NGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCP-SYQS 105
           C+G    G+EK TMQ LNDRLASYLEKVR LE  NA+LE  IR+   +Q P      Y  
Sbjct: 95  CDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSP 154

Query: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165
           Y+KTIEEL+ KIL    EN R++++IDNA+LAADDFR KY+ EL+LRQ VE+DINGLRR+
Sbjct: 155 YYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRV 214

Query: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225
           LDELTL K+DLE Q+ESL EEL  +K NHE+E+     Q+  ++NVE+DA P +DL RVL
Sbjct: 215 LDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVL 274

Query: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
            E R QYEA+ E NRR+ E+WF  ++ ELNK+V +++  +Q+ + EI ELRRT+  LEIE
Sbjct: 275 AEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIE 334

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+Q +++  LENT+ E+E RY+ QL Q+Q LI+++E+QL+E+RS++E QNQEY++LLD+
Sbjct: 335 LQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDI 394

Query: 346 RARLECEINTYRSLLESEDCNLPSNP 371
           + RLE EI TYRSLLE +D      P
Sbjct: 395 KTRLEQEIATYRSLLEGQDAKKRQPP 420


>gi|195972866 keratin 10 [Homo sapiens]
          Length = 584

 Score =  333 bits (853), Expect = 2e-91
 Identities = 179/320 (55%), Positives = 233/320 (72%), Gaps = 9/320 (2%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE------RSQQQEPLLCPSY 103
           G  +G+EK TMQ LNDRLASYL+KVR LE  N ELE  I+E       S Q EP     Y
Sbjct: 140 GLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSHQGEPR---DY 196

Query: 104 QSYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLR 163
             Y+KTI++L+ +IL   ++NA +++QIDNA+LAADDFR KY+ E++LRQ VE+DINGLR
Sbjct: 197 SKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVEADINGLR 256

Query: 164 RILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNR 223
           R+LDELTL K+DLE Q+ESL EEL  LK NHE+E+  LR      +NVE++AAP VDL +
Sbjct: 257 RVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAAPGVDLTQ 316

Query: 224 VLNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALE 283
           +LN  RSQYE L E NR++ E WF  +++EL  ++ ++ EQ+ SY++EI ELRR V ALE
Sbjct: 317 LLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALE 376

Query: 284 IELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLL 343
           IELQ+Q  L+ SLE +L E+E RY  QLSQ+Q+ I+ +E QL +IR++ E QN EYQ LL
Sbjct: 377 IELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQNTEYQQLL 436

Query: 344 DVRARLECEINTYRSLLESE 363
           D++ RLE EI TYRSLLE E
Sbjct: 437 DIKIRLENEIQTYRSLLEGE 456


>gi|4557699 keratin 12 [Homo sapiens]
          Length = 494

 Score =  330 bits (845), Expect = 2e-90
 Identities = 173/318 (54%), Positives = 232/318 (72%), Gaps = 4/318 (1%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRE----RSQQQEPLLCPSYQS 105
           G  +GSEKETMQ LNDRLASYL+KVR LE  N ELEN IRE    R           Y  
Sbjct: 119 GLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSK 178

Query: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165
           Y+  IE+L+ KI+     NA+L++QIDNA+LAA+DFR KY+ EL+LRQ VE+DINGLRR+
Sbjct: 179 YYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRV 238

Query: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225
           LDELTL ++DLE Q+ESL EEL  +K NHE E+ + R      ++VE+DAAP VDL R+L
Sbjct: 239 LDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLL 298

Query: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
           N+ R+QYE + E NR++ E WF  ++ EL K++ +++EQLQS ++E+ +LRR    LEIE
Sbjct: 299 NDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIE 358

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+Q  ++ SLE++L E+E  Y +QLSQVQ LI+N+E+QL ++R+D ERQN ++Q LL+V
Sbjct: 359 LQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNV 418

Query: 346 RARLECEINTYRSLLESE 363
           +ARLE EI TYR LL+ E
Sbjct: 419 KARLELEIETYRRLLDGE 436


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score =  312 bits (799), Expect = 4e-85
 Identities = 158/313 (50%), Positives = 230/313 (73%)

Query: 52  FNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIE 111
           F G+EK  MQ LNDRLASYLEKVR LE+ N++LE  I++  +   P     Y +Y++ IE
Sbjct: 66  FVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYYRQIE 125

Query: 112 ELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTL 171
           EL+ +I   + +NAR V+QIDNAKLAA+DFR KY+TE  +R  VE+D+ GL ++ D+LTL
Sbjct: 126 ELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFDDLTL 185

Query: 172 CKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQ 231
            K+DLE Q+E L ++L  LK  H++EV+ L   LG+ +NVEVDAAP ++L  ++NE R +
Sbjct: 186 HKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEMRQK 245

Query: 232 YEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHN 291
           YE + + N +E ++ F  QT  L +QV  ++E+L+  + ++ ELRRT  +LEIELQ+  +
Sbjct: 246 YEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLS 305

Query: 292 LRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLEC 351
           +++SLE+TL E++ARYSSQL+ +QSL++++E+QL +IRS++ERQN EY +LLD++ RLE 
Sbjct: 306 MKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKTRLEQ 365

Query: 352 EINTYRSLLESED 364
           EI TYR LLE ED
Sbjct: 366 EIATYRRLLEGED 378


>gi|153945736 keratin 27 [Homo sapiens]
          Length = 459

 Score =  300 bits (767), Expect = 2e-81
 Identities = 157/319 (49%), Positives = 219/319 (68%), Gaps = 4/319 (1%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105
           G  +G+EK TMQ LNDRLASYLE VR LE  NA+LE  I+   ++  P  C      Y  
Sbjct: 78  GLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 137

Query: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165
           YF  I+EL+ +I+   + NA +V+Q DNA+L ADDFR K++ EL+L Q VE+DINGLRR+
Sbjct: 138 YFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGLRRV 197

Query: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225
           LDELTLC++DLE Q+E+L EEL  LK NHE+E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 198 LDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLTVLL 257

Query: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
           N  R++YEAL E NRR+ E WF  ++  L +Q+   +    S + E+IE++RT+  LEIE
Sbjct: 258 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNELIEMKRTLQTLEIE 317

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q+ I  +E QL ++R++ E Q  EY+ LLD+
Sbjct: 318 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 377

Query: 346 RARLECEINTYRSLLESED 364
           +  LE EI TY  L++ ED
Sbjct: 378 KVHLEKEIETYCLLIDGED 396


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score =  297 bits (761), Expect = 1e-80
 Identities = 155/319 (48%), Positives = 219/319 (68%), Gaps = 5/319 (1%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS-----YQ 104
           G F+G EK+TMQ LNDRLA+YL+KVR LE  N +LEN I+E   +  P          Y 
Sbjct: 134 GLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSGDGGSGRDYS 193

Query: 105 SYFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRR 164
            Y+  IE+L+ +I+    ENA +++ IDNA+LAADDFR KY+ EL LRQ VE+DINGLR+
Sbjct: 194 KYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSVEADINGLRK 253

Query: 165 ILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRV 224
           +LD+LT+ +SDLE Q+ES  EEL  L+ NHE+E+  ++   G  + VE++AAP  DL ++
Sbjct: 254 VLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNAAPGTDLTKL 313

Query: 225 LNETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEI 284
           LN+ R+QYE L E NRRE E+ F  Q+  L  Q+ + +    S + EI EL+RT+ ALEI
Sbjct: 314 LNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITELKRTLQALEI 373

Query: 285 ELQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLD 344
           ELQ+Q  ++ SLE TL ++EA Y +QLS++Q+ I+ +E ++ +I  + + QN EY+ LLD
Sbjct: 374 ELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQNAEYKQLLD 433

Query: 345 VRARLECEINTYRSLLESE 363
           ++ RLE EI TYR LL+ E
Sbjct: 434 IKTRLEVEIETYRRLLDGE 452


>gi|114431246 keratin 25D [Homo sapiens]
          Length = 464

 Score =  297 bits (760), Expect = 1e-80
 Identities = 160/338 (47%), Positives = 224/338 (66%), Gaps = 15/338 (4%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105
           G  +G+EK TMQ LNDRLASYL+ VR LE  NAELE  I+   ++  P  C      Y  
Sbjct: 80  GLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELERKIKGWYEKYGPGSCRGLDHDYSR 139

Query: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165
           Y  TIE+L+ KI+ + + NA +++QIDNA+LAADDFR KY+ EL+L Q VE+DINGLRR+
Sbjct: 140 YHLTIEDLKNKIISSTTTNANVILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRV 199

Query: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225
           LDELTLC++D E Q ESL EE+  LK NHE+E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 200 LDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKALQCAAGGNVNVEMNAAPGVDLAVLL 259

Query: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
           N  R++YEAL E NR++ E WF  ++  L +Q+   S      ++++ E+RRT+  LEI+
Sbjct: 260 NNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHDSGAATFARSQLTEMRRTLQTLEIQ 319

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q+ I  +E QL ++R++ E Q  EY+ LLDV
Sbjct: 320 LQSLMATKHSLECSLTETESNYCTQLAQIQAQIGALEEQLHQVRTETEGQKLEYEHLLDV 379

Query: 346 RARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIG 383
           +  LE EI TY  L++ +            N+CSK  G
Sbjct: 380 KVHLEKEIETYCRLIDGDG-----------NSCSKSKG 406


>gi|40354195 keratin 18 [Homo sapiens]
          Length = 430

 Score =  293 bits (751), Expect = 2e-79
 Identities = 151/315 (47%), Positives = 227/315 (72%), Gaps = 3/315 (0%)

Query: 55  SEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQ 114
           +EKETMQ LNDRLASYL++VR LE +N  LE+ IRE  +++ P +   +  YFK IE+L+
Sbjct: 79  NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137

Query: 115 QKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKS 174
            +I     +NAR+V+QIDNA+LAADDFR KY+TEL++RQ VE+DI+GLR+++D+  + + 
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197

Query: 175 DLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRSQYE 233
            LE ++E+LKEELL +K NHE+EV  L+ Q+    L VEVDA  + DL +++ + R+QY+
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257

Query: 234 ALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
            L   NR E++++++ Q EE    V + S ++ + +  + ELRRTV +LEI+L +  NL+
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317

Query: 294 DSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
            SLEN+L E EARY+ Q+ Q+  ++ ++ES+LA+ R++ +RQ QEY+ LL+++ +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377

Query: 354 NTYRSLLE-SEDCNL 367
            TYR LLE  ED NL
Sbjct: 378 ATYRRLLEDGEDFNL 392


>gi|4557888 keratin 18 [Homo sapiens]
          Length = 430

 Score =  293 bits (751), Expect = 2e-79
 Identities = 151/315 (47%), Positives = 227/315 (72%), Gaps = 3/315 (0%)

Query: 55  SEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQ 114
           +EKETMQ LNDRLASYL++VR LE +N  LE+ IRE  +++ P +   +  YFK IE+L+
Sbjct: 79  NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137

Query: 115 QKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKS 174
            +I     +NAR+V+QIDNA+LAADDFR KY+TEL++RQ VE+DI+GLR+++D+  + + 
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197

Query: 175 DLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDR-LNVEVDAAPTVDLNRVLNETRSQYE 233
            LE ++E+LKEELL +K NHE+EV  L+ Q+    L VEVDA  + DL +++ + R+QY+
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257

Query: 234 ALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
            L   NR E++++++ Q EE    V + S ++ + +  + ELRRTV +LEI+L +  NL+
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317

Query: 294 DSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
            SLEN+L E EARY+ Q+ Q+  ++ ++ES+LA+ R++ +RQ QEY+ LL+++ +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377

Query: 354 NTYRSLLE-SEDCNL 367
            TYR LLE  ED NL
Sbjct: 378 ATYRRLLEDGEDFNL 392


>gi|31559829 keratin 25 [Homo sapiens]
          Length = 450

 Score =  291 bits (745), Expect = 7e-79
 Identities = 155/349 (44%), Positives = 226/349 (64%), Gaps = 4/349 (1%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPS----YQS 105
           G  +G+EK TMQ LNDRLASYL+ V  LE  NA+LE  I+   ++  P  C      Y  
Sbjct: 73  GLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYSR 132

Query: 106 YFKTIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRI 165
           YF  I++L+ +I+ + + NA  V+QIDNA+L ADDFR KY+ EL+L Q VE+D+NGLRR+
Sbjct: 133 YFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRRV 192

Query: 166 LDELTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVL 225
           LDE+TLC++DLE Q E+L EE+  LK NH++E+  L+C  G  +NVE++AAP VDL  +L
Sbjct: 193 LDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVLL 252

Query: 226 NETRSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIE 285
           N  R++YEAL E NRR+ E WF  ++  L +Q+        S + E+ E++RT+  LEIE
Sbjct: 253 NNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEIE 312

Query: 286 LQAQHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDV 345
           LQ+    + SLE +LTE+E+ Y +QL+Q+Q+ I  +E QL ++R++ E Q  EY+ LLD+
Sbjct: 313 LQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLDI 372

Query: 346 RARLECEINTYRSLLESEDCNLPSNPCATTNACSKPIGPCLSNPCTSCV 394
           +  LE EI TY  L+  +D    S    + +  S  +G  + +P  + V
Sbjct: 373 KLHLEKEIETYCLLIGGDDGACKSGGYKSKDYGSGNVGSQVKDPAKAIV 421


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score =  270 bits (690), Expect = 2e-72
 Identities = 137/313 (43%), Positives = 213/313 (68%), Gaps = 1/313 (0%)

Query: 50  GSFNGSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPL-LCPSYQSYFK 108
           G    +EK TMQ LN RLASYL+KV+ LE  N +LEN I++   ++ P  +  +Y  Y+ 
Sbjct: 147 GILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQKNYSPYYN 206

Query: 109 TIEELQQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDE 168
           TI++L+ +I+     N + ++ IDN ++  DDFR K++ E +LRQ V++DINGLR++LD 
Sbjct: 207 TIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADINGLRQVLDN 266

Query: 169 LTLCKSDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNET 228
           LT+ KSDLE Q E+L+EEL+ LK NH++E++ L  Q    +NVE++ AP  DL + LN+ 
Sbjct: 267 LTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLTKTLNDM 326

Query: 229 RSQYEALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQA 288
           R +YE L+  NR+++E  + TQ  ++  +V SS +++QS   E+ +LR  V  LEIELQ+
Sbjct: 327 RQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQS 386

Query: 289 QHNLRDSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRAR 348
           Q + + +LE +L +++ RY  QL  +Q  I+N+E+Q+ ++R ++E QNQEY +LL ++ R
Sbjct: 387 QLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYSLLLSIKMR 446

Query: 349 LECEINTYRSLLE 361
           LE EI TY +LLE
Sbjct: 447 LEKEIETYHNLLE 459


>gi|27894339 keratin 23 [Homo sapiens]
          Length = 422

 Score =  267 bits (682), Expect = 2e-71
 Identities = 136/310 (43%), Positives = 209/310 (67%), Gaps = 1/310 (0%)

Query: 54  GSEKETMQFLNDRLASYLEKVRQLERDNAELENLIRERSQQQEPLLCPSYQSYFKTIEEL 113
           G+ K TMQ LNDRLASYLEKVR LE  N +LE+ I +  QQ++P     Y  Y + I  L
Sbjct: 70  GNGKATMQNLNDRLASYLEKVRALEEANMKLESRILKWHQQRDPGSKKDYSQYEENITHL 129

Query: 114 QQKILCTKSENARLVVQIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCK 173
           Q++I+  K  NA++++ IDNA++A DDF  KY+ E S ++ +E ++ GLRR LD LT+  
Sbjct: 130 QEQIVDGKMTNAQIILLIDNARMAVDDFNLKYENEHSFKKDLEIEVEGLRRTLDNLTIVT 189

Query: 174 SDLEAQVESLKEELLCLKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYE 233
           +DLE +VE +++EL+ +K +HEQE+          +NV+VD  P  DL +VL + R +YE
Sbjct: 190 TDLEQEVEGMRKELILMKKHHEQEMEKHHVPSDFNVNVKVDTGPREDLIKVLEDMRQEYE 249

Query: 234 ALVETNRREVEQWFTTQTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLR 293
            +++   R+++ W+  Q+  ++++  S +  +QS Q +I EL+RT  ALEI+LQ Q++ +
Sbjct: 250 LIIKKKHRDLDTWYKEQSAAMSQEAASPA-TVQSRQGDIHELKRTFQALEIDLQTQYSTK 308

Query: 294 DSLENTLTESEARYSSQLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEI 353
            +LEN L+E+++RYS +L  +Q +I++ E +L ++R +LERQN EYQVLL ++  LE EI
Sbjct: 309 SALENMLSETQSRYSCKLQDMQEIISHYEEELTQLRHELERQNNEYQVLLGIKTHLEKEI 368

Query: 354 NTYRSLLESE 363
            TYR LLE E
Sbjct: 369 TTYRRLLEGE 378


>gi|31559815 keratin 26 [Homo sapiens]
          Length = 468

 Score =  267 bits (682), Expect = 2e-71
 Identities = 155/355 (43%), Positives = 216/355 (60%), Gaps = 15/355 (4%)

Query: 25  SCHSCTLPGA------CNIPANVSN--CNWFCEGS---FNGSEKETMQFLNDRLASYLEK 73
           S  SCTL G       CN    + +  C  F        +G+EK TMQ LNDRLASYL+ 
Sbjct: 41  SSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHSLLSGNEKVTMQNLNDRLASYLDH 100

Query: 74  VRQLERDNAELENLIRERSQQQEPLLCPS----YQSYFKTIEELQQKILCTKSENARLVV 129
           V  LE  NA+LE  I+ R ++ EP         Y  YF  IE+L+++I      NA +V+
Sbjct: 101 VHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRYFSVIEDLKRQITSATICNASIVL 160

Query: 130 QIDNAKLAADDFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLC 189
           Q DNA+L ADDFR KY+ EL+L   VE+D +GLRR+LDELTLC +DLE Q E+L EEL  
Sbjct: 161 QNDNARLTADDFRLKYENELALHHSVEADTSGLRRVLDELTLCTTDLEIQCETLSEELTY 220

Query: 190 LKSNHEQEVNTLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTT 249
           LK +HE+E+  L+   G  +NVE++A P VDL  +LN  R++YE L E NR++ E WF  
Sbjct: 221 LKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLNNMRAEYEDLAEQNRKDAEAWFNE 280

Query: 250 QTEELNKQVVSSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSS 309
           ++  L +Q+        + + E+ EL+R +  LEIELQ+   ++ S E +L E+E  Y +
Sbjct: 281 RSATLQQQISDHEGAATAARNELTELKRNLQTLEIELQSLMAVKHSYECSLAETEGNYCN 340

Query: 310 QLSQVQSLITNVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESED 364
           QL Q+Q  I  +E QL +IR++ E Q  EY+ LLDV+  LE EI+ Y +LL+ E+
Sbjct: 341 QLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVKIFLEKEIDIYCNLLDGEE 395


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,476,178
Number of Sequences: 37866
Number of extensions: 704706
Number of successful extensions: 8060
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 226
Number of HSP's successfully gapped in prelim test: 617
Number of HSP's that attempted gapping in prelim test: 5088
Number of HSP's gapped (non-prelim): 2588
length of query: 416
length of database: 18,247,518
effective HSP length: 105
effective length of query: 311
effective length of database: 14,271,588
effective search space: 4438463868
effective search space used: 4438463868
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.