Search of human proteins with 109659839

Search of human proteins with 109659839

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109659839 solute carrier family 5 (sodium/glucose
cotransporter), member 10 isoform 1 [Homo sapiens]
         (612 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109659839 solute carrier family 5 (sodium/glucose cotransport...  1222   0.0  
gi|109659836 solute carrier family 5 (sodium/glucose cotransport...  1180   0.0  
gi|206597483 solute carrier family 5 (sodium/glucose cotransport...   729   0.0  
gi|206597487 solute carrier family 5 (sodium/glucose cotransport...   715   0.0  
gi|4507031 solute carrier family 5 (sodium/glucose cotransporter...   657   0.0  
gi|4507033 solute carrier family 5 (sodium/glucose cotransporter...   642   0.0  
gi|17941285 solute carrier family 5 (sodium/glucose cotransporte...   630   e-180
gi|14140236 solute carrier family 5 (low affinity glucose cotran...   592   e-169
gi|110835708 solute carrier family 5 (inositol transporters), me...   587   e-167
gi|10863879 solute carrier family 5 (sodium-dependent vitamin tr...   134   2e-31
gi|157671931 solute carrier family 5 (sodium/glucose cotransport...   119   1e-26
gi|167466278 solute carrier family 5 (iodide transporter), membe...   107   4e-23
gi|4507035 solute carrier family 5 (sodium iodide symporter), me...   101   2e-21
gi|11141885 solute carrier family 5 (choline transporter), membe...    78   3e-14
gi|218931253 diacylglycerol lipase, beta isoform 2 [Homo sapiens]      37   0.041
gi|239753837 PREDICTED: similar to Uncharacterized protein LP905...    32   1.3  
gi|239748400 PREDICTED: hypothetical protein XP_002346661 [Homo ...    32   1.3  
gi|239742330 PREDICTED: hypothetical protein XP_002342492 [Homo ...    32   1.3  
gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo s...    31   2.9  
gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo s...    31   2.9  
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi...    31   2.9  
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]    31   2.9  
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]    31   2.9  
gi|171184408 solute carrier family 6 (neurotransmitter transport...    31   3.8  
gi|171184406 solute carrier family 6 (neurotransmitter transport...    31   3.8  
gi|171184404 solute carrier family 6 (neurotransmitter transport...    31   3.8  
gi|217416366 major facilitator superfamily domain containing 9 [...    30   5.0  
gi|157388953 G protein-coupled receptor 172B [Homo sapiens]            30   5.0  
gi|157388951 G protein-coupled receptor 172B [Homo sapiens]            30   5.0  
gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]          30   6.5  

>gi|109659839 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 1 [Homo sapiens]
          Length = 612

 Score = 1222 bits (3163), Expect = 0.0
 Identities = 612/612 (100%), Positives = 612/612 (100%)

Query: 1   MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWW 60
           MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWW
Sbjct: 1   MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWW 60

Query: 61  PIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTL 120
           PIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTL
Sbjct: 61  PIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTL 120

Query: 121 PEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGIT 180
           PEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGIT
Sbjct: 121 PEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGIT 180

Query: 181 ALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANT 240
           ALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANT
Sbjct: 181 ALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANT 240

Query: 241 TCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAG 300
           TCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAG
Sbjct: 241 TCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAG 300

Query: 301 SILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGA 360
           SILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGA
Sbjct: 301 SILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGA 360

Query: 361 EVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRS 420
           EVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRS
Sbjct: 361 EVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRS 420

Query: 421 GERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFW 480
           GERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFW
Sbjct: 421 GERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFW 480

Query: 481 RRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALS 540
           RRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALS
Sbjct: 481 RRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALS 540

Query: 541 GAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILL 600
           GAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILL
Sbjct: 541 GAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILL 600

Query: 601 MCVNIFFYAYFA 612
           MCVNIFFYAYFA
Sbjct: 601 MCVNIFFYAYFA 612


>gi|109659836 solute carrier family 5 (sodium/glucose
           cotransporter), member 10 isoform 2 [Homo sapiens]
          Length = 596

 Score = 1180 bits (3053), Expect = 0.0
 Identities = 596/612 (97%), Positives = 596/612 (97%), Gaps = 16/612 (2%)

Query: 1   MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWW 60
           MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWW
Sbjct: 1   MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWW 60

Query: 61  PIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTL 120
           PIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTL
Sbjct: 61  PIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTL 120

Query: 121 PEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGIT 180
           PEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGIT
Sbjct: 121 PEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGIT 180

Query: 181 ALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANT 240
           ALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANT
Sbjct: 181 ALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANT 240

Query: 241 TCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAG 300
           TCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAG
Sbjct: 241 TCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAG 300

Query: 301 SILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGA 360
           SILASYLKMLPMGLIIMPGMISRALFP                DDVGCVVPSECLRACGA
Sbjct: 301 SILASYLKMLPMGLIIMPGMISRALFP----------------DDVGCVVPSECLRACGA 344

Query: 361 EVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRS 420
           EVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRS
Sbjct: 345 EVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRS 404

Query: 421 GERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFW 480
           GERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFW
Sbjct: 405 GERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFW 464

Query: 481 RRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALS 540
           RRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALS
Sbjct: 465 RRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALS 524

Query: 541 GAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILL 600
           GAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILL
Sbjct: 525 GAVVVAGSLLTPPPQSVQIENLTWWTLAQDVPLGTKAGDGQTPQKHAFWARVCGFNAILL 584

Query: 601 MCVNIFFYAYFA 612
           MCVNIFFYAYFA
Sbjct: 585 MCVNIFFYAYFA 596


>gi|206597483 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 2 [Homo sapiens]
          Length = 681

 Score =  729 bits (1882), Expect = 0.0
 Identities = 350/551 (63%), Positives = 432/551 (78%), Gaps = 16/551 (2%)

Query: 16  LSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGL 75
           L   DI V+ +YF   +AVGIWSS RASR T+ GYFLAGR M+WWPIGASL +S+ GSGL
Sbjct: 33  LHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGL 92

Query: 76  FIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135
           FIGLAG+GAAGGLAV GFEWNAT++LLAL WVFVP+YI++ +VT+P+Y++KR+GGQRI++
Sbjct: 93  FIGLAGTGAAGGLAVGGFEWNATWLLLALGWVFVPVYIAAGVVTMPQYLKKRFGGQRIQV 152

Query: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195
           Y+SVLSL+L +FTKIS D+++GALF+ + LGWN YLST + L +TA+YTIAGGL AVIYT
Sbjct: 153 YMSVLSLILYIFTKISTDIFSGALFIQMALGWNLYLSTGILLVVTAVYTIAGGLMAVIYT 212

Query: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRD 255
           DALQT+IMV GA++L    F  +G Y  LE  Y QAIP+ T+ NTTCHLPR DA H+ RD
Sbjct: 213 DALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQAIPNVTVPNTTCHLPRPDAFHILRD 272

Query: 256 PHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLI 315
           P +GD+PW G+ FGLT++ATW WCTDQVIVQRSLSA+ L+HAK GS+L  YLK+LPM  I
Sbjct: 273 PVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLSAKSLSHAKGGSVLGGYLKILPMFFI 332

Query: 316 IMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVME 375
           +MPGMISRALFP                D+VGCV P  C R CGA VGCSNIAYPKLVM 
Sbjct: 333 VMPGMISRALFP----------------DEVGCVDPDVCQRICGARVGCSNIAYPKLVMA 376

Query: 376 LMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVA 435
           LMP+GLRGLMIAV++AALMSSLTSIFNSSSTLFT+D+W+R R +S E+EL++VGR+ +V 
Sbjct: 377 LMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTIDVWQRFRRKSTEQELMVVGRVFVVF 436

Query: 436 LIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAG 495
           L+ +S+ WIP++Q SNSGQLF Y+Q+VTS LAPP+TA+F+L +F +R  E GAFWGL+ G
Sbjct: 437 LVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPITALFLLAIFCKRVTEPGAFWGLVFG 496

Query: 496 LVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPPPQ 555
           L VG  R++LEF  PAP CGE D RPAVL   HYL+FA+ L  L+  V+V  SL T P  
Sbjct: 497 LGVGLLRMILEFSYPAPACGEVDRRPAVLKDFHYLYFAILLCGLTAIVIVIVSLCTTPIP 556

Query: 556 SVQIENLTWWT 566
             Q+  LTWWT
Sbjct: 557 EEQLTRLTWWT 567



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 13/29 (44%), Positives = 19/29 (65%)

Query: 584 QKHAFWARVCGFNAILLMCVNIFFYAYFA 612
           ++   W  VC  NA+LL+ +NIF + YFA
Sbjct: 653 EEEPLWRHVCNINAVLLLAINIFLWGYFA 681


>gi|206597487 solute carrier family 5 (sodium/glucose
           cotransporter), member 9 isoform 1 [Homo sapiens]
          Length = 706

 Score =  715 bits (1846), Expect = 0.0
 Identities = 350/576 (60%), Positives = 432/576 (75%), Gaps = 41/576 (7%)

Query: 16  LSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGL 75
           L   DI V+ +YF   +AVGIWSS RASR T+ GYFLAGR M+WWPIGASL +S+ GSGL
Sbjct: 33  LHAYDISVVVIYFVFVIAVGIWSSIRASRGTIGGYFLAGRSMSWWPIGASLMSSNVGSGL 92

Query: 76  FIGLAGSGAAGGLAVAGFEWN-------------------------ATYVLLALAWVFVP 110
           FIGLAG+GAAGGLAV GFEWN                         AT++LLAL WVFVP
Sbjct: 93  FIGLAGTGAAGGLAVGGFEWNMRKSRSGGDRGIHPRSHGRTGVRSQATWLLLALGWVFVP 152

Query: 111 IYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFY 170
           +YI++ +VT+P+Y++KR+GGQRI++Y+SVLSL+L +FTKIS D+++GALF+ + LGWN Y
Sbjct: 153 VYIAAGVVTMPQYLKKRFGGQRIQVYMSVLSLILYIFTKISTDIFSGALFIQMALGWNLY 212

Query: 171 LSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQ 230
           LST + L +TA+YTIAGGL AVIYTDALQT+IMV GA++L    F  +G Y  LE  Y Q
Sbjct: 213 LSTGILLVVTAVYTIAGGLMAVIYTDALQTVIMVGGALVLMFLGFQDVGWYPGLEQRYRQ 272

Query: 231 AIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLS 290
           AIP+ T+ NTTCHLPR DA H+ RDP +GD+PW G+ FGLT++ATW WCTDQVIVQRSLS
Sbjct: 273 AIPNVTVPNTTCHLPRPDAFHILRDPVSGDIPWPGLIFGLTVLATWCWCTDQVIVQRSLS 332

Query: 291 ARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVV 350
           A+ L+HAK GS+L  YLK+LPM  I+MPGMISRALFP                D+VGCV 
Sbjct: 333 AKSLSHAKGGSVLGGYLKILPMFFIVMPGMISRALFP----------------DEVGCVD 376

Query: 351 PSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTM 410
           P  C R CGA VGCSNIAYPKLVM LMP+GLRGLMIAV++AALMSSLTSIFNSSSTLFT+
Sbjct: 377 PDVCQRICGARVGCSNIAYPKLVMALMPVGLRGLMIAVIMAALMSSLTSIFNSSSTLFTI 436

Query: 411 DIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPV 470
           D+W+R R +S E+EL++VGR+ +V L+ +S+ WIP++Q SNSGQLF Y+Q+VTS LAPP+
Sbjct: 437 DVWQRFRRKSTEQELMVVGRVFVVFLVVISILWIPIIQSSNSGQLFDYIQAVTSYLAPPI 496

Query: 471 TAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYL 530
           TA+F+L +F +R  E GAFWGL+ GL VG  R++LEF  PAP CGE D RPAVL   HYL
Sbjct: 497 TALFLLAIFCKRVTEPGAFWGLVFGLGVGLLRMILEFSYPAPACGEVDRRPAVLKDFHYL 556

Query: 531 HFAVALFALSGAVVVAGSLLTPPPQSVQIENLTWWT 566
           +FA+ L  L+  V+V  SL T P    Q+  LTWWT
Sbjct: 557 YFAILLCGLTAIVIVIVSLCTTPIPEEQLTRLTWWT 592



 Score = 37.7 bits (86), Expect = 0.031
 Identities = 13/29 (44%), Positives = 19/29 (65%)

Query: 584 QKHAFWARVCGFNAILLMCVNIFFYAYFA 612
           ++   W  VC  NA+LL+ +NIF + YFA
Sbjct: 678 EEEPLWRHVCNINAVLLLAINIFLWGYFA 706


>gi|4507031 solute carrier family 5 (sodium/glucose cotransporter),
           member 1 [Homo sapiens]
          Length = 664

 Score =  657 bits (1695), Expect = 0.0
 Identities = 310/553 (56%), Positives = 413/553 (74%), Gaps = 21/553 (3%)

Query: 17  SVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLF 76
           + ADI +I +YF + +AVG+W+    +R TV G+FLAGR M WWPIGASLFAS+ GSG F
Sbjct: 25  NAADISIIVIYFVVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHF 84

Query: 77  IGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMY 136
           +GLAG+GAA G+A+ GFEWNA  +++ L W+FVPIYI + +VT+PEY++KR+GGQRI++Y
Sbjct: 85  VGLAGTGAASGIAIGGFEWNALVLVVVLGWLFVPIYIKAGVVTMPEYLRKRFGGQRIQVY 144

Query: 137 LSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTD 196
           LS+LSLLL +FTKIS D+++GA+F+++ LG N YL+  L L ITALYTI GGLAAVIYTD
Sbjct: 145 LSLLSLLLYIFTKISADIFSGAIFINLALGLNLYLAIFLLLAITALYTITGGLAAVIYTD 204

Query: 197 ALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPS-----RTIANTTCHLPRTDAMH 251
            LQT+IM+VG++ILT  AF ++GGY      Y +AIP+      T     C+ PR D+ H
Sbjct: 205 TLQTVIMLVGSLILTGFAFHEVGGYDAFMEKYMKAIPTIVSDGNTTFQEKCYTPRADSFH 264

Query: 252 MFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLP 311
           +FRDP TGDLPW G  FG++I+  WYWCTDQVIVQR LSA++++H K G IL  YLK++P
Sbjct: 265 IFRDPLTGDLPWPGFIFGMSILTLWYWCTDQVIVQRCLSAKNMSHVKGGCILCGYLKLMP 324

Query: 312 MGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPK 371
           M +++MPGMISR L+                T+ + CVVPSEC + CG +VGC+NIAYP 
Sbjct: 325 MFIMVMPGMISRILY----------------TEKIACVVPSECEKYCGTKVGCTNIAYPT 368

Query: 372 LVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRL 431
           LV+ELMP GLRGLM++VMLA+LMSSLTSIFNS+STLFTMDI+ ++R R+ E+EL++ GRL
Sbjct: 369 LVVELMPNGLRGLMLSVMLASLMSSLTSIFNSASTLFTMDIYAKVRKRASEKELMIAGRL 428

Query: 432 VIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWG 491
            I+ LIG+S+AW+P++Q + SGQLF Y+QS+TS L PP+ AVF+L +FW+R NE GAFWG
Sbjct: 429 FILVLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWG 488

Query: 492 LIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLT 551
           LI GL++G +R++ EF      C EP   P ++  +HYL+FA+ LFA+S   +V  SLLT
Sbjct: 489 LILGLLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFAISFITIVVISLLT 548

Query: 552 PPPQSVQIENLTW 564
            P   V +  L W
Sbjct: 549 KPIPDVHLYRLCW 561


>gi|4507033 solute carrier family 5 (sodium/glucose cotransporter),
           member 2 [Homo sapiens]
          Length = 672

 Score =  642 bits (1655), Expect = 0.0
 Identities = 314/543 (57%), Positives = 401/543 (73%), Gaps = 24/543 (4%)

Query: 19  ADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIG 78
           ADI+VI  YF L + VG+WS CR +R TV GYFLAGR M WWP+GASLFAS+ GSG F+G
Sbjct: 24  ADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVG 83

Query: 79  LAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLS 138
           LAG+GAA GLAVAGFEWNA +V+L L W+F P+Y+++ ++T+P+Y++KR+GG+RIR+YLS
Sbjct: 84  LAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTAGVITMPQYLRKRFGGRRIRLYLS 143

Query: 139 VLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDAL 198
           VLSL L +FTKIS+D+++GA+F+   LGWN Y S I  LGIT +YT+ GGLAA++YTD +
Sbjct: 144 VLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIALLGITMIYTVTGGLAALMYTDTV 203

Query: 199 QTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIA--------NTTCHLPRTDAM 250
           QT +++ GA IL   AF ++GGY  L   Y  A  S T++        ++ C+ PR D+ 
Sbjct: 204 QTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSY 263

Query: 251 HMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKML 310
           H+ R P TGDLPW  +  GLTI++ WYWC+DQVIVQR L+ + L H KAG IL  YLK+ 
Sbjct: 264 HLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQRCLAGKSLTHIKAGCILCGYLKLT 323

Query: 311 PMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYP 370
           PM L++MPGMISR L+P                D+V CVVP  C R CG EVGCSNIAYP
Sbjct: 324 PMFLMVMPGMISRILYP----------------DEVACVVPEVCRRVCGTEVGCSNIAYP 367

Query: 371 KLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGR 430
           +LV++LMP GLRGLM+AVMLAALMSSL SIFNSSSTLFTMDI+ RLRPR+G+RELLLVGR
Sbjct: 368 RLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDRELLLVGR 427

Query: 431 LVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFW 490
           L +V ++ VSVAW+PV+Q +  GQLF Y+Q+V+S LAPPV+AVFVL +F  R NEQGAFW
Sbjct: 428 LWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRVNEQGAFW 487

Query: 491 GLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLL 550
           GLI GL++G  RL+ EF   +  C +P   PA L  +HYL+FA+ LF  SG + +  SL 
Sbjct: 488 GLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLLTLTVSLC 547

Query: 551 TPP 553
           T P
Sbjct: 548 TAP 550



 Score = 31.2 bits (69), Expect = 2.9
 Identities = 11/24 (45%), Positives = 17/24 (70%)

Query: 589 WARVCGFNAILLMCVNIFFYAYFA 612
           WARV   NA+L+M V +F + ++A
Sbjct: 649 WARVVNLNALLMMAVAVFLWGFYA 672


>gi|17941285 solute carrier family 5 (sodium/glucose cotransporter),
           member 11 [Homo sapiens]
          Length = 675

 Score =  630 bits (1624), Expect = e-180
 Identities = 300/555 (54%), Positives = 408/555 (73%), Gaps = 16/555 (2%)

Query: 12  PGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSE 71
           P   L   DI V+ +YF   +AVG+WS+ +  R+TV GYFLAG DM WWP+GASLFAS+ 
Sbjct: 20  PQKGLEPGDIAVLVLYFLFVLAVGLWSTVKTKRDTVKGYFLAGGDMVWWPVGASLFASNV 79

Query: 72  GSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQ 131
           GSG FIGLAGSGAA G++V+ +E N  + +L LAW+F+PIYI+ ++ T+PEY++KR+GG 
Sbjct: 80  GSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLRKRFGGI 139

Query: 132 RIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAA 191
           RI + L+VL L + +FTKIS+D+YAGA+F+   L  + YL+ +  L ITA+YT+AGGLAA
Sbjct: 140 RIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAA 199

Query: 192 VIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMH 251
           VIYTDALQTLIM++GA+ L   +F  +GG   L+  Y  A+ S    N++C LPR DA H
Sbjct: 200 VIYTDALQTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFH 259

Query: 252 MFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLP 311
           +FRDP T DLPW G+ FG++I + WYWCTDQVIVQR+L+A++L+HAK G+++A+YLK+LP
Sbjct: 260 IFRDPLTSDLPWPGVLFGMSIPSLWYWCTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLP 319

Query: 312 MGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPK 371
           + +++ PGM+SR LFP                D V C  P  C + C    GCS+IAYPK
Sbjct: 320 LFIMVFPGMVSRILFP----------------DQVACADPEICQKICSNPSGCSDIAYPK 363

Query: 372 LVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRL 431
           LV+EL+P GLRGLM+AVM+AALMSSLTSIFNS+ST+FTMD+W  LRPR+ E+EL++VGR+
Sbjct: 364 LVLELLPTGLRGLMMAVMVAALMSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRV 423

Query: 432 VIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWG 491
            ++ L+ VS+ WIPV+Q S  GQLFIY+QS++S L PPV  VF++G FW+R NE+GAFWG
Sbjct: 424 FVLLLVLVSILWIPVVQASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFWG 483

Query: 492 LIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLT 551
           LI+GL++G  RLVL+F+   P C +PD RP ++ SIHYL+F++ L  ++   V   S  T
Sbjct: 484 LISGLLLGLVRLVLDFIYVQPRCDQPDERPVLVKSIHYLYFSMILSTVTLITVSTVSWFT 543

Query: 552 PPPQSVQIENLTWWT 566
            PP    + +LTW+T
Sbjct: 544 EPPSKEMVSHLTWFT 558


>gi|14140236 solute carrier family 5 (low affinity glucose
           cotransporter), member 4 [Homo sapiens]
          Length = 659

 Score =  592 bits (1526), Expect = e-169
 Identities = 279/553 (50%), Positives = 392/553 (70%), Gaps = 21/553 (3%)

Query: 17  SVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLF 76
           + ADI VI +YF + +AVG+W+  + +R T+ G+FLAGRDM WWP+GASLFAS+ GS  +
Sbjct: 25  NAADISVIVIYFLVVMAVGLWAMLKTNRGTIGGFFLAGRDMAWWPMGASLFASNIGSNHY 84

Query: 77  IGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMY 136
           +GLAG+GAA G+A   FEW ++ +LL L W+FVPIYI S ++T+PEY++KR+GG+R+++Y
Sbjct: 85  VGLAGTGAASGVATVTFEWTSSVMLLILGWIFVPIYIKSGVMTMPEYLKKRFGGERLQVY 144

Query: 137 LSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTD 196
           LS+LSL + V   IS D++AGA+F+ + LG + YL+  + L +TA+YT  GGLA+VIYTD
Sbjct: 145 LSILSLFICVVLLISADIFAGAIFIKLALGLDLYLAIFILLAMTAVYTTTGGLASVIYTD 204

Query: 197 ALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPS-----RTIANTTCHLPRTDAMH 251
            LQT+IM++G+ IL   AF+++GGY      Y  A PS         + +C+ PR D+ H
Sbjct: 205 TLQTIIMLIGSFILMGFAFNEVGGYESFTEKYVNATPSVVEGDNLTISASCYTPRADSFH 264

Query: 252 MFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLP 311
           +FRD  TGD+PW G+ FG+ I A WYWCT+QVIVQR L  +D++H KA  I+ +YLK+LP
Sbjct: 265 IFRDAVTGDIPWPGIIFGMPITALWYWCTNQVIVQRCLCGKDMSHVKAACIMCAYLKLLP 324

Query: 312 MGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPK 371
           M L++MPGMISR L+                TD V CVVPSEC++ CG +VGC+N AYP 
Sbjct: 325 MFLMVMPGMISRILY----------------TDMVACVVPSECVKHCGVDVGCTNYAYPT 368

Query: 372 LVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRL 431
           +V+ELMP GLRGLM++VMLA+LMSSLTSIFNS+STLFT+D++ ++R ++ E+ELL+ GR+
Sbjct: 369 MVLELMPQGLRGLMLSVMLASLMSSLTSIFNSASTLFTIDLYTKMRKQASEKELLIAGRI 428

Query: 432 VIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWG 491
            ++ L  VS+ W+P++Q S +GQL  Y +S++S L PP+ AVFVL +F +R NEQGAFWG
Sbjct: 429 FVLLLTVVSIVWVPLVQVSQNGQLIHYTESISSYLGPPIAAVFVLAIFCKRVNEQGAFWG 488

Query: 492 LIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLT 551
           L+ GL +G  R++ EF      C  P   P ++  +HYL+F++ LF  S  V +  SLLT
Sbjct: 489 LMVGLAMGLIRMITEFAYGTGSCLAPSNCPKIICGVHYLYFSIVLFFGSMLVTLGISLLT 548

Query: 552 PPPQSVQIENLTW 564
            P   V +  L W
Sbjct: 549 KPIPDVHLYRLCW 561


>gi|110835708 solute carrier family 5 (inositol transporters),
           member 3 [Homo sapiens]
          Length = 718

 Score =  587 bits (1513), Expect = e-167
 Identities = 278/560 (49%), Positives = 396/560 (70%), Gaps = 25/560 (4%)

Query: 16  LSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGL 75
           L  ADI ++ +YF L + +G ++  +++R+TV+GYFLAGR MTW  IGASLF S+ GS  
Sbjct: 5   LDTADIAIVALYFILVMCIGFFAMWKSNRSTVSGYFLAGRSMTWVTIGASLFVSNIGSEH 64

Query: 76  FIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135
           FIGLAGSGAA G AV  +E+NA  +L  L WVF+PIYI S + T+PEY+ KR+GG RI++
Sbjct: 65  FIGLAGSGAASGFAVGAWEFNALLLLQLLGWVFIPIYIRSGVYTMPEYLSKRFGGHRIQV 124

Query: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195
           Y + LSL+L +FTK+S+DLY+GALF+   LGWN Y+S IL +G+TAL T+ GGL AVIYT
Sbjct: 125 YFAALSLILYIFTKLSVDLYSGALFIQESLGWNLYVSVILLIGMTALLTVTGGLVAVIYT 184

Query: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRT-------IANT-TCHL-PR 246
           D LQ L+M++GA+ L I +  +IGG+ +++  Y  A P  T       ++NT +C++ P+
Sbjct: 185 DTLQALLMIIGALTLMIISIMEIGGFEEVKRRYMLASPDVTSILLTYNLSNTNSCNVSPK 244

Query: 247 TDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASY 306
            +A+ M R+P   D+PW G   G T  + WYWC DQVIVQR L+A+++ HAK  +++A +
Sbjct: 245 KEALKMLRNPTDEDVPWPGFILGQTPASVWYWCADQVIVQRVLAAKNIAHAKGSTLMAGF 304

Query: 307 LKMLPMGLIIMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSN 366
           LK+LPM +I++PGMISR LF                TDD+ C+ P  C+  CG+  GCSN
Sbjct: 305 LKLLPMFIIVVPGMISRILF----------------TDDIACINPEHCMLVCGSRAGCSN 348

Query: 367 IAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELL 426
           IAYP+LVM+L+P+GLRGLM+AVM+AALMS L SIFNS+ST+FT+D+++ +R  +  REL+
Sbjct: 349 IAYPRLVMKLVPVGLRGLMMAVMIAALMSDLDSIFNSASTIFTLDVYKLIRKSASSRELM 408

Query: 427 LVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQ 486
           +VGR+ +  ++ +S+AW+P++ +   GQ+++Y+Q V   L PPV A+F+L +FW+R NEQ
Sbjct: 409 IVGRIFVAFMVVISIAWVPIIVEMQGGQMYLYIQEVADYLTPPVAALFLLAIFWKRCNEQ 468

Query: 487 GAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVA 546
           GAF+G +AG V+GA RL+L F   AP C +PD RP  +  IHY++ A  LF ++G + V 
Sbjct: 469 GAFYGGMAGFVLGAVRLILAFAYRAPECDQPDNRPGFIKDIHYMYVATGLFWVTGLITVI 528

Query: 547 GSLLTPPPQSVQIENLTWWT 566
            SLLTPPP   QI   T+W+
Sbjct: 529 VSLLTPPPTKEQIRTTTFWS 548


>gi|10863879 solute carrier family 5 (sodium-dependent vitamin
           transporter), member 6 [Homo sapiens]
          Length = 635

 Score =  134 bits (338), Expect = 2e-31
 Identities = 128/500 (25%), Positives = 230/500 (46%), Gaps = 54/500 (10%)

Query: 6   TSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRA-SRNTVNGYFLAGRDMTWWPIGA 64
           TS      +  S+ D +V  +   L++A+G++ +CR   R+TV    +A R M   P+  
Sbjct: 14  TSGTSVGMSTFSIMDYVVFVLLLVLSLAIGLYHACRGWGRHTVGELLMADRKMGCLPVAL 73

Query: 65  SLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYI 124
           SL A+ + +   +G+       G             LL  A +F+P++    + +  EY+
Sbjct: 74  SLLATFQSAVAILGVPSEIYRFGTQYWFLGCCYFLGLLIPAHIFIPVFYRLHLTSAYEYL 133

Query: 125 QKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITA-LY 183
           + R+  + +R+    ++ +  +   + + LYA +L ++   G++ +LS +L LGI   +Y
Sbjct: 134 ELRFN-KTVRV-CGTVTFIFQMVIYMGVVLYAPSLALNAVTGFDLWLS-VLALGIVCTVY 190

Query: 184 TIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCH 243
           T  GGL AVI+TD  QTL+M +G + + I    ++GG G++ A  +Q             
Sbjct: 191 TALGGLKAVIWTDVFQTLVMFLGQLAVIIVGSAKVGGLGRVWAVASQH------------ 238

Query: 244 LPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSIL 303
             R     +  DP      WT + FG   M    +  +Q  VQR LS+R     +  ++L
Sbjct: 239 -GRISGFELDPDPFVRHTFWT-LAFGGVFMMLSLYGVNQAQVQRYLSSR----TEKAAVL 292

Query: 304 ASYLKMLPMGLIIMPG-MISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEV 362
           + Y       + +  G +I   +F     Y + + +S+ +        P +         
Sbjct: 293 SCYAVFPFQQVSLCVGCLIGLVMF----AYYQEYPMSIQQAQ----AAPDQF-------- 336

Query: 363 GCSNIAYPKLVMELMP--IGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRS 420
               + Y   VM+L+    GL GL IA + +  +S+++S FNS +T+   D+ R   P  
Sbjct: 337 ----VLY--FVMDLLKGLPGLPGLFIACLFSGSLSTISSAFNSLATVTMEDLIRPWFPEF 390

Query: 421 GERELLLVGRLVI--VALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGV 478
            E   +++ R +     L+ + +A+I     S  G +     S+   +  P+  +F LG+
Sbjct: 391 SEARAIMLSRGLAFGYGLLCLGMAYI----SSQMGPVLQAAISIFGMVGGPLLGLFCLGM 446

Query: 479 FWRRANEQGAFWGLIAGLVV 498
           F+  AN  GA  GL+AGLV+
Sbjct: 447 FFPCANPPGAVVGLLAGLVM 466


>gi|157671931 solute carrier family 5 (sodium/glucose
           cotransporter), member 12 [Homo sapiens]
          Length = 618

 Score =  119 bits (297), Expect = 1e-26
 Identities = 117/500 (23%), Positives = 217/500 (43%), Gaps = 48/500 (9%)

Query: 17  SVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAG-RDMTWWPIGASLFASSEGSGL 75
           +V D +V    F ++  +G++ + +  +   +  FL G R M++ P+G SL AS   +  
Sbjct: 7   AVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVT 66

Query: 76  FIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135
            +G        G +   F     +V+L  + +F+P++  S I +  EY+Q R+  + +R 
Sbjct: 67  VLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFN-KPVR- 124

Query: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195
           Y + +  ++       + +YA AL ++   G++ + S   T  +   Y   GGL AV++T
Sbjct: 125 YAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWT 184

Query: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRD 255
           DA Q ++M+VG + + I+     GG+          +  ++   +  H+   D      D
Sbjct: 185 DAFQMVVMIVGFLTVLIQGSTHAGGF--------HNVLEQSTNGSRLHIFDFDV-----D 231

Query: 256 PHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLI 315
           P      WT +T G T      +  +Q  +QR +S +   HAK    LA Y  +L + +I
Sbjct: 232 PLRRHTFWT-ITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAK----LALYFNLLGLWII 286

Query: 316 IMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVME 375
           ++      A+F G  +Y                    +C       +   +   P  VME
Sbjct: 287 LV-----CAVFSGLIMYSHF----------------KDCDPWTSGIISAPDQLMPYFVME 325

Query: 376 L---MPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLV 432
           +   MP GL GL +A   +  +S++ S  N+ +T+   D  +   P   ++    + +  
Sbjct: 326 IFATMP-GLPGLFVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISK-G 383

Query: 433 IVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGL 492
           +  L GV    + V      G +   + S+      P+  +F LG+ +   N +GA  GL
Sbjct: 384 LCLLFGVMCTSMAVAASVMGGVVQASL-SIHGMCGGPMLGLFSLGIVFPFVNWKGALGGL 442

Query: 493 IAGLVVGATRLVLEFLNPAP 512
           + G+ +     +  F+ PAP
Sbjct: 443 LTGITLSFWVAIGAFIYPAP 462


>gi|167466278 solute carrier family 5 (iodide transporter), member 8
           [Homo sapiens]
          Length = 610

 Score =  107 bits (266), Expect = 4e-23
 Identities = 116/486 (23%), Positives = 209/486 (43%), Gaps = 50/486 (10%)

Query: 18  VADIIVITVYFALNVAVGIWSS-CRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLF 76
           V D +V      ++ A+GI+ +     + T   + + GR MT  P+  SL AS   +   
Sbjct: 12  VWDYVVFAGMLVISAAIGIYYAFAGGGQQTSKDFLMGGRRMTAVPVALSLTASFMSAVTV 71

Query: 77  IGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMY 136
           +G        G   + F +   +V++  A VF+P++    I +  EY++ R+  + +R+ 
Sbjct: 72  LGTPSEVYRFGAIFSIFAFTYFFVVVISAEVFLPVFYKLGITSTYEYLELRFN-KCVRLC 130

Query: 137 LSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTD 196
            +VL ++ ++     + +YA AL ++   G++ + + + T  +   Y   GGL AVI+TD
Sbjct: 131 GTVLFIVQTILYT-GIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVIWTD 189

Query: 197 ALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDP 256
             Q  IMV G   + I+A    GG               TI N      R +  +   +P
Sbjct: 190 VFQVGIMVAGFASVIIQAVVMQGGIS-------------TILNDAYDGGRLNFWNFNPNP 236

Query: 257 HTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLII 316
                 WT +  G T   T  +  +Q  VQR +S +    AK    L+ Y+ ++ +  I 
Sbjct: 237 LQRHTFWT-IIIGGTFTWTSIYGVNQSQVQRYISCKSRFQAK----LSLYINLVGLWAI- 290

Query: 317 MPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVMEL 376
               ++ ++F G  +Y   H                +C      +V   +   P LV+++
Sbjct: 291 ----LTCSVFCGLALYSRYH----------------DCDPWTAKKVSAPDQLMPYLVLDI 330

Query: 377 MP--IGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLV--GRLV 432
           +    GL GL +A   +  +S+++S  N+ + +   D+ +       ER L  +  G  V
Sbjct: 331 LQDYPGLPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPYFRSLSERSLSWISQGMSV 390

Query: 433 IVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGL 492
           +   + + +A +  L     G L     SV   +  P+  +F LG+    AN  GA  GL
Sbjct: 391 VYGALCIGMAALASLM----GALLQAALSVFGMVGGPLMGLFALGILVPFANSIGALVGL 446

Query: 493 IAGLVV 498
           +AG  +
Sbjct: 447 MAGFAI 452


>gi|4507035 solute carrier family 5 (sodium iodide symporter),
           member 5 [Homo sapiens]
          Length = 643

 Score =  101 bits (252), Expect = 2e-21
 Identities = 128/602 (21%), Positives = 237/602 (39%), Gaps = 100/602 (16%)

Query: 20  DIIVITVYFALNVAVGIWSS-CRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIG 78
           D  V  +   ++  +G+W    R  + +   +F  GR +   P+G SL AS   +   +G
Sbjct: 16  DYGVFALMLLVSTGIGLWVGLARGGQRSAEDFFTGGRRLAALPVGLSLSASFMSAVQVLG 75

Query: 79  LAGSGAAGGLAVAGFEWNATYVLL---ALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRM 135
           +       GL    F W     LL     A +F+P++    + +  EY++ R+   R   
Sbjct: 76  VPSEAYRYGLK---FLWMCLGQLLNSVLTALLFMPVFYRLGLTSTYEYLEMRFS--RAVR 130

Query: 136 YLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYT 195
               L  +++      + +YA AL ++   G + + S + T  I   YT  GG+ AV++T
Sbjct: 131 LCGTLQYIVATMLYTGIVIYAPALILNQVTGLDIWASLLSTGIICTFYTAVGGMKAVVWT 190

Query: 196 DALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRD 255
           D  Q ++M+ G  ++  +    +GG              R +     +  R + M    D
Sbjct: 191 DVFQVVVMLSGFWVVLARGVMLVGG-------------PRQVLTLAQNHSRINLMDFNPD 237

Query: 256 PHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLI 315
           P +    WT +  G  +  + Y   +Q  VQR ++ R    AK   ++        +GL 
Sbjct: 238 PRSRYTFWTFVVGGTLVWLSMYG-VNQAQVQRYVACRTEKQAKLALLINQ------VGLF 290

Query: 316 IMPGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVGCSNIAYPKLVME 375
           ++   +S A   G  ++                V  ++C       +   +   P LV++
Sbjct: 291 LI---VSSAACCGIVMF----------------VFYTDCDPLLLGRISAPDQYMPLLVLD 331

Query: 376 LMPI--GLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVI 433
           +     G+ GL +A   +  +S+ ++  N+ + +   D+ +        R+L+++ + + 
Sbjct: 332 IFEDLPGVPGLFLACAYSGTLSTASTSINAMAAVTVEDLIKPRLRSLAPRKLVIISKGLS 391

Query: 434 VALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLI 493
           + + G +   +  L     G +     +V   ++ P+   F+LG+F    N  G   GL 
Sbjct: 392 L-IYGSACLTVAALSSLLGGGVLQGSFTVMGVISGPLLGAFILGMFLPACNTPGVLAGLG 450

Query: 494 AGLVV-----------------------GATRLVLEFLNP----------------APPC 514
           AGL +                        A R V   +N                 AP  
Sbjct: 451 AGLALSLWVALGATLYPPSEQTMRVLPSSAARCVALSVNASGLLDPALLPANDSSRAPSS 510

Query: 515 GEPDTRPAVLGS---IHYLHFAVALFALSGAVVVAGSLLT----PPPQSVQIENLTWWTL 567
           G   +RPA+  S   I YL++  AL  L+   V+ G+L++    P  +S     L WW L
Sbjct: 511 GMDASRPALADSFYAISYLYYG-ALGTLT--TVLCGALISCLTGPTKRSTLAPGLLWWDL 567

Query: 568 AQ 569
           A+
Sbjct: 568 AR 569


>gi|11141885 solute carrier family 5 (choline transporter), member 7
           [Homo sapiens]
          Length = 580

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 113/499 (22%), Positives = 215/499 (43%), Gaps = 70/499 (14%)

Query: 18  VADIIVITVYFALNVAVGIWSSCR-----ASRNTVNGYFLAGRDMTWWPIGASLFASSEG 72
           V  +I I V++ L + VGIW++ R     ++        + GRD+     G ++ A+  G
Sbjct: 5   VEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVG 64

Query: 73  SGLFIGLAGSGAAGGLAVAGFEWNATYVL-LALAWVFVPIYISSE-IVTLPEYIQKRYGG 130
            G   G A +    G  +A  +    Y L L L  +F    + S+  VT+ +  Q+ YG 
Sbjct: 65  GGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYG- 123

Query: 131 QRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLA 190
           +R+   L + +L+  +F   ++    GA  + + +  + ++S I++  I  LYT+ GGL 
Sbjct: 124 KRMGGLLFIPALMGEMFWAAAIFSALGAT-ISVIIDVDMHISVIISALIATLYTLVGGLY 182

Query: 191 AVIYTDALQTLIMVVGAVI-----LTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLP 245
           +V YTD +Q   + VG  I     L+  A   I G+  + A Y +  P     +++    
Sbjct: 183 SVAYTDVVQLFCIFVGLWISVPFALSHPAVADI-GFTAVHAKYQK--PWLGTVDSSEVYS 239

Query: 246 RTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILAS 305
             D+  +      G +PW                  Q   QR LS+    +A+  S LA+
Sbjct: 240 WLDSFLLLM---LGGIPW------------------QAYFQRVLSSSSATYAQVLSFLAA 278

Query: 306 YLKMLPMGLIIM--PGMISRALFPGAHVYEERHQVSVSRTDDVGCVVPSECLRACGAEVG 363
           +      G ++M  P ++  A+       +  + +   +T +                  
Sbjct: 279 F------GCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEE----------------- 315

Query: 364 CSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWR-RLRPRSGE 422
            +++  P ++  L P+ +    +  + AA+MSS  S   S+S++F  +I++   R  + +
Sbjct: 316 -ADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASD 374

Query: 423 RELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRR 482
           +E++ V R + V + G S   + +L  +  G  ++    V   + P +  V    +F + 
Sbjct: 375 KEIVWVMR-ITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCV----LFVKG 429

Query: 483 ANEQGAFWGLIAGLVVGAT 501
            N  GA  G ++GL +  T
Sbjct: 430 TNTYGAVAGYVSGLFLRIT 448


>gi|218931253 diacylglycerol lipase, beta isoform 2 [Homo sapiens]
          Length = 543

 Score = 37.4 bits (85), Expect = 0.041
 Identities = 37/125 (29%), Positives = 54/125 (43%), Gaps = 3/125 (2%)

Query: 129 GGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICL-GWNFYLSTILTLGITALYT--I 185
           GG  +  YL VL +LL+V       +   ++   IC  G    +S +L + +   +   +
Sbjct: 51  GGALLSSYLIVLMILLAVVICTVSAIMCVSMRGTICNPGPRKSMSKLLYIRLALFFPEMV 110

Query: 186 AGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLP 245
              L A    D +Q    VV  +I T+    QI     L  A    I +RTI+ TT  LP
Sbjct: 111 WASLGAAWVADGVQCDRTVVNGIIATVVVRTQIWCPATLRRASPCFISNRTISGTTKSLP 170

Query: 246 RTDAM 250
           R  AM
Sbjct: 171 RWSAM 175


>gi|239753837 PREDICTED: similar to Uncharacterized protein LP9056
           [Homo sapiens]
          Length = 563

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 28  FALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGG 87
           + L  A G W    AS     G+    R  TWW  G++L  S   SGLF  L G+G   G
Sbjct: 251 YGLTEAHGKWRCADASITNDKGHD-GHRTPTWWLTGSNLTLSVNNSGLFF-LCGNGVYKG 308


>gi|239748400 PREDICTED: hypothetical protein XP_002346661 [Homo
           sapiens]
          Length = 563

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 28  FALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGG 87
           + L  A G W    AS     G+    R  TWW  G++L  S   SGLF  L G+G   G
Sbjct: 251 YGLTEAHGKWRCADASITNDKGHD-GHRTPTWWLTGSNLTLSVNNSGLFF-LCGNGVYKG 308


>gi|239742330 PREDICTED: hypothetical protein XP_002342492 [Homo
           sapiens]
          Length = 563

 Score = 32.3 bits (72), Expect = 1.3
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 28  FALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGG 87
           + L  A G W    AS     G+    R  TWW  G++L  S   SGLF  L G+G   G
Sbjct: 251 YGLTEAHGKWRCADASITNDKGHD-GHRTPTWWLTGSNLTLSVNNSGLFF-LCGNGVYKG 308


>gi|91718897 mitogen-activated protein kinase 3 isoform 2 [Homo
           sapiens]
          Length = 357

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 31/148 (20%), Positives = 58/148 (39%), Gaps = 29/148 (19%)

Query: 233 PSRTIANTTCHLPRTD-AMHMFRDP---HTGDLPWTGMTFGLTIMATWYWCTDQVIVQRS 288
           PS  + NTTC L   D  +    DP   HTG        F    +AT ++   ++++   
Sbjct: 169 PSNLLINTTCDLKICDFGLARIADPEHDHTG--------FLTEYVATRWYRAPEIMLNSK 220

Query: 289 LSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQV----SVSRTD 344
              + ++    G ILA  L              +R +FPG H  ++ + +         +
Sbjct: 221 GYTKSIDIWSVGCILAEMLS-------------NRPIFPGKHYLDQLNHILGILGSPSQE 267

Query: 345 DVGCVVPSECLRACGAEVGCSNIAYPKL 372
           D+ C++  +      +    + +A+ KL
Sbjct: 268 DLNCIINMKARNYLQSLPSKTKVAWAKL 295


>gi|91718899 mitogen-activated protein kinase 3 isoform 1 [Homo
           sapiens]
          Length = 379

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 31/148 (20%), Positives = 58/148 (39%), Gaps = 29/148 (19%)

Query: 233 PSRTIANTTCHLPRTD-AMHMFRDP---HTGDLPWTGMTFGLTIMATWYWCTDQVIVQRS 288
           PS  + NTTC L   D  +    DP   HTG        F    +AT ++   ++++   
Sbjct: 169 PSNLLINTTCDLKICDFGLARIADPEHDHTG--------FLTEYVATRWYRAPEIMLNSK 220

Query: 289 LSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQV----SVSRTD 344
              + ++    G ILA  L              +R +FPG H  ++ + +         +
Sbjct: 221 GYTKSIDIWSVGCILAEMLS-------------NRPIFPGKHYLDQLNHILGILGSPSQE 267

Query: 345 DVGCVVPSECLRACGAEVGCSNIAYPKL 372
           D+ C++  +      +    + +A+ KL
Sbjct: 268 DLNCIINMKARNYLQSLPSKTKVAWAKL 295


>gi|190684655 glucose transporter protein 10 isoform a [Homo
           sapiens]
          Length = 503

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 9/162 (5%)

Query: 372 LVMELMPIG-LRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGR 430
           L++ L P+G L G ++A  LA  +    S+  ++  + +  I      ++G  E++++GR
Sbjct: 76  LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 135

Query: 431 LVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFW 490
           L++    GVS+   P+    ++ +      +++S++   +  V    V  R        W
Sbjct: 136 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 195

Query: 491 GLIAG--LVVGATRLVLEFLNPAPP------CGEPDTRPAVL 524
            L+    LV GA +L    L P  P      CG+ +   A L
Sbjct: 196 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL 237


>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
          Length = 496

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 9/162 (5%)

Query: 372 LVMELMPIG-LRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGR 430
           L++ L P+G L G ++A  LA  +    S+  ++  + +  I      ++G  E++++GR
Sbjct: 69  LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 128

Query: 431 LVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFW 490
           L++    GVS+   P+    ++ +      +++S++   +  V    V  R        W
Sbjct: 129 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 188

Query: 491 GLIAG--LVVGATRLVLEFLNPAPP------CGEPDTRPAVL 524
            L+    LV GA +L    L P  P      CG+ +   A L
Sbjct: 189 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL 230


>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
          Length = 499

 Score = 31.2 bits (69), Expect = 2.9
 Identities = 38/162 (23%), Positives = 72/162 (44%), Gaps = 9/162 (5%)

Query: 372 LVMELMPIG-LRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGR 430
           L++ L P+G L G ++A  LA  +    S+  ++  + +  I      ++G  E++++GR
Sbjct: 72  LIVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGR 131

Query: 431 LVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFW 490
           L++    GVS+   P+    ++ +      +++S++   +  V    V  R        W
Sbjct: 132 LLVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAW 191

Query: 491 GLIAG--LVVGATRLVLEFLNPAPP------CGEPDTRPAVL 524
            L+    LV GA +L    L P  P      CG+ +   A L
Sbjct: 192 PLLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAAL 233


>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 6/80 (7%)

Query: 363 GCSNIAYPKLVMELMPIG-LRGLMIAVMLAALMSSLTSIFNSSSTLFT--MDIWRRLRPR 419
           G + IA+PK V  +MP+  L   +  +ML  L   L S F     L T  +D++ R   +
Sbjct: 361 GLAFIAFPKAVT-MMPLSQLWSCLFFIMLIFL--GLDSQFVCVECLVTASIDMFPRQLRK 417

Query: 420 SGERELLLVGRLVIVALIGV 439
           SG RELL++   V+  LIG+
Sbjct: 418 SGRRELLILTIAVMCYLIGL 437


>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 6/80 (7%)

Query: 363 GCSNIAYPKLVMELMPIG-LRGLMIAVMLAALMSSLTSIFNSSSTLFT--MDIWRRLRPR 419
           G + IA+PK V  +MP+  L   +  +ML  L   L S F     L T  +D++ R   +
Sbjct: 361 GLAFIAFPKAVT-MMPLSQLWSCLFFIMLIFL--GLDSQFVCVECLVTASIDMFPRQLRK 417

Query: 420 SGERELLLVGRLVIVALIGV 439
           SG RELL++   V+  LIG+
Sbjct: 418 SGRRELLILTIAVMCYLIGL 437


>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 29/80 (36%), Positives = 43/80 (53%), Gaps = 6/80 (7%)

Query: 363 GCSNIAYPKLVMELMPIG-LRGLMIAVMLAALMSSLTSIFNSSSTLFT--MDIWRRLRPR 419
           G + IA+PK V  +MP+  L   +  +ML  L   L S F     L T  +D++ R   +
Sbjct: 361 GLAFIAFPKAVT-MMPLSQLWSCLFFIMLIFL--GLDSQFVCVECLVTASIDMFPRQLRK 417

Query: 420 SGERELLLVGRLVIVALIGV 439
           SG RELL++   V+  LIG+
Sbjct: 418 SGRRELLILTIAVMCYLIGL 437


>gi|217416366 major facilitator superfamily domain containing 9
           [Homo sapiens]
          Length = 474

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 22/125 (17%)

Query: 95  WNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQ-RIRMYLSVLSLLLSVFTKISLD 153
           W+   V L +A   V +Y S+ ++ L E    R+G + ++  YL   S +L     ++L 
Sbjct: 286 WDIFLVRLLMAMA-VMLYYSNFVLALEE----RFGVRPKVTGYLISYSSMLGAVAGLALG 340

Query: 154 ----LY---AGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVG 206
               LY   + AL +H         S+ILT  +  LY++A  + AV+ +  L +    +G
Sbjct: 341 PILRLYKHNSQALLLH---------SSILTCTLLLLYSLAPTMGAVVLSSTLLSFSTAIG 391

Query: 207 AVILT 211
              +T
Sbjct: 392 RTCIT 396


>gi|157388953 G protein-coupled receptor 172B [Homo sapiens]
          Length = 448

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 6/98 (6%)

Query: 453 GQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAP 512
           G+L  ++  V  S A P+     +GV  R     G     + G++ GA  + L  L+P P
Sbjct: 309 GRLAYHLAVVLGSAANPLACFLAMGVLCRSL--AGLVGLSLLGMLFGAYLMALAILSPCP 366

Query: 513 PCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLL 550
           P     T   V+  +  L + + L   S   V A SLL
Sbjct: 367 PL--VGTTAGVV--LVVLSWVLCLCVFSYVKVAASSLL 400


>gi|157388951 G protein-coupled receptor 172B [Homo sapiens]
          Length = 448

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 6/98 (6%)

Query: 453 GQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAP 512
           G+L  ++  V  S A P+     +GV  R     G     + G++ GA  + L  L+P P
Sbjct: 309 GRLAYHLAVVLGSAANPLACFLAMGVLCRSL--AGLVGLSLLGMLFGAYLMALAILSPCP 366

Query: 513 PCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLL 550
           P     T   V+  +  L + + L   S   V A SLL
Sbjct: 367 PL--VGTTAGVV--LVVLSWVLCLCVFSYVKVAASSLL 400


>gi|20986531 mitogen-activated protein kinase 1 [Homo sapiens]
          Length = 360

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 28/126 (22%), Positives = 50/126 (39%), Gaps = 29/126 (23%)

Query: 233 PSRTIANTTCHLPRTD-AMHMFRDP---HTGDLPWTGMTFGLTIMATWYWCTDQVIVQRS 288
           PS  + NTTC L   D  +    DP   HTG        F    +AT ++   ++++   
Sbjct: 152 PSNLLLNTTCDLKICDFGLARVADPDHDHTG--------FLTEYVATRWYRAPEIMLNSK 203

Query: 289 LSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPGAHVYEERHQV----SVSRTD 344
              + ++    G ILA  L              +R +FPG H  ++ + +         +
Sbjct: 204 GYTKSIDIWSVGCILAEMLS-------------NRPIFPGKHYLDQLNHILGILGSPSQE 250

Query: 345 DVGCVV 350
           D+ C++
Sbjct: 251 DLNCII 256


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.138    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,518,996
Number of Sequences: 37866
Number of extensions: 901561
Number of successful extensions: 2825
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2766
Number of HSP's gapped (non-prelim): 41
length of query: 612
length of database: 18,247,518
effective HSP length: 108
effective length of query: 504
effective length of database: 14,157,990
effective search space: 7135626960
effective search space used: 7135626960
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.