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Search of human proteins with 109637753
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109637753 calpastatin isoform a [Homo sapiens]
(791 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109637753 calpastatin isoform a [Homo sapiens] 1562 0.0
gi|109637761 calpastatin isoform g [Homo sapiens] 1513 0.0
gi|109637763 calpastatin isoform h [Homo sapiens] 1504 0.0
gi|109637757 calpastatin isoform e [Homo sapiens] 1468 0.0
gi|109637759 calpastatin isoform f [Homo sapiens] 1454 0.0
gi|109637765 calpastatin isoform i [Homo sapiens] 1405 0.0
gi|27765085 calpastatin isoform b [Homo sapiens] 1347 0.0
gi|109637769 calpastatin isoform k [Homo sapiens] 1311 0.0
gi|109637767 calpastatin isoform j [Homo sapiens] 1297 0.0
gi|109637771 calpastatin isoform l [Homo sapiens] 1262 0.0
gi|27765087 calpastatin isoform c [Homo sapiens] 781 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 93 1e-18
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 73 1e-12
gi|104526627 triadin [Homo sapiens] 71 3e-12
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 70 8e-12
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 70 8e-12
gi|150170670 piccolo isoform 2 [Homo sapiens] 68 4e-11
gi|150378539 piccolo isoform 1 [Homo sapiens] 68 4e-11
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 67 5e-11
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 67 6e-11
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 67 6e-11
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 64 4e-10
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 64 5e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 64 7e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 64 7e-10
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 64 7e-10
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 64 7e-10
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 64 7e-10
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 64 7e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 63 9e-10
>gi|109637753 calpastatin isoform a [Homo sapiens]
Length = 791
Score = 1562 bits (4045), Expect = 0.0
Identities = 791/791 (100%), Positives = 791/791 (100%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
Query: 121 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST
Sbjct: 121 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
Query: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 240
EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL
Sbjct: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 240
Query: 241 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 300
DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG
Sbjct: 241 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 300
Query: 301 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 360
PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK
Sbjct: 301 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 360
Query: 361 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 420
KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS
Sbjct: 361 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 420
Query: 421 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 480
EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA
Sbjct: 421 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 480
Query: 481 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 540
AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK
Sbjct: 481 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 540
Query: 541 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 600
VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE
Sbjct: 541 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 600
Query: 601 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 660
DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS
Sbjct: 601 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 660
Query: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 720
LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK
Sbjct: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 720
Query: 721 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 780
SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK
Sbjct: 721 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 780
Query: 781 TTEETSKPKDD 791
TTEETSKPKDD
Sbjct: 781 TTEETSKPKDD 791
>gi|109637761 calpastatin isoform g [Homo sapiens]
Length = 772
Score = 1513 bits (3916), Expect = 0.0
Identities = 772/791 (97%), Positives = 772/791 (97%), Gaps = 19/791 (2%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
Query: 121 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
KSQSTK PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST
Sbjct: 121 KSQSTK-------------------PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 161
Query: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 240
EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL
Sbjct: 162 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 221
Query: 241 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 300
DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG
Sbjct: 222 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 281
Query: 301 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 360
PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK
Sbjct: 282 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 341
Query: 361 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 420
KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS
Sbjct: 342 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 401
Query: 421 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 480
EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA
Sbjct: 402 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 461
Query: 481 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 540
AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK
Sbjct: 462 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 521
Query: 541 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 600
VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE
Sbjct: 522 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 581
Query: 601 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 660
DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS
Sbjct: 582 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 641
Query: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 720
LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK
Sbjct: 642 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 701
Query: 721 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 780
SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK
Sbjct: 702 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 761
Query: 781 TTEETSKPKDD 791
TTEETSKPKDD
Sbjct: 762 TTEETSKPKDD 772
>gi|109637763 calpastatin isoform h [Homo sapiens]
Length = 769
Score = 1504 bits (3893), Expect = 0.0
Identities = 769/791 (97%), Positives = 769/791 (97%), Gaps = 22/791 (2%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
YAGGTASATKVSASSGATSKSSSMNPTETKA VKTEPEK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKA----------------------VKTEPEK 98
Query: 121 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST
Sbjct: 99 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 158
Query: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 240
EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL
Sbjct: 159 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 218
Query: 241 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 300
DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG
Sbjct: 219 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 278
Query: 301 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 360
PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK
Sbjct: 279 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 338
Query: 361 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 420
KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS
Sbjct: 339 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 398
Query: 421 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 480
EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA
Sbjct: 399 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 458
Query: 481 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 540
AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK
Sbjct: 459 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 518
Query: 541 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 600
VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE
Sbjct: 519 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 578
Query: 601 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 660
DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS
Sbjct: 579 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 638
Query: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 720
LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK
Sbjct: 639 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 698
Query: 721 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 780
SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK
Sbjct: 699 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 758
Query: 781 TTEETSKPKDD 791
TTEETSKPKDD
Sbjct: 759 TTEETSKPKDD 769
>gi|109637757 calpastatin isoform e [Homo sapiens]
Length = 756
Score = 1468 bits (3801), Expect = 0.0
Identities = 756/791 (95%), Positives = 756/791 (95%), Gaps = 35/791 (4%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
YAGGTASATKVSASSGATSKSSSMNPTETKA VKTEPEK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKA----------------------VKTEPEK 98
Query: 121 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST
Sbjct: 99 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 158
Query: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 240
EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL
Sbjct: 159 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 218
Query: 241 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 300
DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK
Sbjct: 219 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAK------ 272
Query: 301 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 360
PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK
Sbjct: 273 -------PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 325
Query: 361 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 420
KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS
Sbjct: 326 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 385
Query: 421 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 480
EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA
Sbjct: 386 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 445
Query: 481 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 540
AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK
Sbjct: 446 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 505
Query: 541 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 600
VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE
Sbjct: 506 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 565
Query: 601 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 660
DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS
Sbjct: 566 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 625
Query: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 720
LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK
Sbjct: 626 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 685
Query: 721 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 780
SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK
Sbjct: 686 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 745
Query: 781 TTEETSKPKDD 791
TTEETSKPKDD
Sbjct: 746 TTEETSKPKDD 756
>gi|109637759 calpastatin isoform f [Homo sapiens]
Length = 750
Score = 1454 bits (3764), Expect = 0.0
Identities = 750/791 (94%), Positives = 750/791 (94%), Gaps = 41/791 (5%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT
Sbjct: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEK 120
YAGGTASATKVSASSGATSKSSSMNPTETKA VKTEPEK
Sbjct: 61 YAGGTASATKVSASSGATSKSSSMNPTETKA----------------------VKTEPEK 98
Query: 121 KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
KSQSTK PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST
Sbjct: 99 KSQSTK-------------------PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 139
Query: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 240
EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL
Sbjct: 140 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAAL 199
Query: 241 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 300
DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG
Sbjct: 200 DDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITG 259
Query: 301 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 360
PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK
Sbjct: 260 PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEK 319
Query: 361 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 420
KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS
Sbjct: 320 KRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS 379
Query: 421 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 480
EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA
Sbjct: 380 EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKA 439
Query: 481 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 540
AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK
Sbjct: 440 AAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 499
Query: 541 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 600
VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE
Sbjct: 500 VKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSE 559
Query: 601 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 660
DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS
Sbjct: 560 DFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDS 619
Query: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 720
LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK
Sbjct: 620 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK 679
Query: 721 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 780
SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK
Sbjct: 680 SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAK 739
Query: 781 TTEETSKPKDD 791
TTEETSKPKDD
Sbjct: 740 TTEETSKPKDD 750
>gi|109637765 calpastatin isoform i [Homo sapiens]
Length = 708
Score = 1405 bits (3638), Expect = 0.0
Identities = 708/708 (100%), Positives = 708/708 (100%)
Query: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH
Sbjct: 1 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 60
Query: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 61 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 120
Query: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 121 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 180
Query: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT
Sbjct: 181 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 240
Query: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 383
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 241 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 300
Query: 384 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 443
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 301 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 360
Query: 444 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 503
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 361 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 420
Query: 504 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 563
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 421 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 480
Query: 564 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 623
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 481 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 540
Query: 624 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 683
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 541 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 600
Query: 684 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 743
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 601 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 660
Query: 744 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 661 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 708
Score = 221 bits (564), Expect = 2e-57
Identities = 196/668 (29%), Positives = 315/668 (47%), Gaps = 71/668 (10%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 81 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 140
Query: 72 SASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVH 131
+ S S M+ I + GP ++ ++ T PE + +
Sbjct: 141 ESKPDKPSGKSGMDAALDDLI---DTLGGP----EETEEENTTYTGPEVSDPMSSTYIEE 193
Query: 132 EKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMIS 191
K + P ++ E L K+ TG P S++P P D I
Sbjct: 194 LGKREVTIPPKYRE--LLAKKEGITG-----------------PPADSSKP-IGPDDAID 233
Query: 192 A-GGESVAGITAISGKPGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDD 242
A + G +GK +K++ + ++ A P + K K + D AL+
Sbjct: 234 ALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA 293
Query: 243 LIDTLGGPEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--I 298
L +L G + E E + EV + + +E+ G+ + TIP +YR + K+G +
Sbjct: 294 LSASL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL 352
Query: 299 TGPPADSSKPIGPDDAIDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSA 348
P + KP + ID LS DF P+ +KTE+ ++ +E + S
Sbjct: 353 LPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSM 412
Query: 349 GTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKL 408
+++SA P + K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE
Sbjct: 413 CSIQSAPP----EPATLKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDR 467
Query: 409 EKCGEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEK 467
EK GE +ETIP +YRL+ DKDGKPLLP E +E+ P SE L+D LSEDF +
Sbjct: 468 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ---- 523
Query: 468 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGK 526
+ + K E++K A A +SE V +T + Q+ APP + DDA++ L+DSLG+
Sbjct: 524 -NASSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQ 580
Query: 527 KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKE 584
++ DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+YR + KP+ P K+S++
Sbjct: 581 RQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 640
Query: 585 QLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTS 644
P + +DALS D + + AK + S+ P + +A + T
Sbjct: 641 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 700
Query: 645 QSDKDLDD 652
++ K DD
Sbjct: 701 ETSKPKDD 708
Score = 80.9 bits (198), Expect = 4e-15
Identities = 100/387 (25%), Positives = 162/387 (41%), Gaps = 51/387 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 353 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 410
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 411 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 467
Query: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
EK + + + E K ++GKP LPK+ +K+ + +E
Sbjct: 468 EKLGEKEETIPPDYRLEEVKDKDGKP-------LLPKE----------SKEQLPPMSEDF 510
Query: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGK 233
+ +E + PQ+ S E AIS E S TPA ++ P + + +
Sbjct: 511 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSQ 562
Query: 234 S--GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYREL 291
S +D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR L
Sbjct: 563 SDKDLDDALDKLSDSLGQRQPDPDENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHL 621
Query: 292 LAK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLK 344
L ++ PP DS KP D IDALS D +C S T + T K++ +
Sbjct: 622 LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAAS 681
Query: 345 AQSA----GTVRSAAPPQEKKRKVEKD 367
+ A G + +A E+ K + D
Sbjct: 682 SSKAPKNGGKAKDSAKTTEETSKPKDD 708
>gi|27765085 calpastatin isoform b [Homo sapiens]
Length = 686
Score = 1347 bits (3486), Expect = 0.0
Identities = 686/708 (96%), Positives = 686/708 (96%), Gaps = 22/708 (3%)
Query: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
MNPTETKA VKTEPEKKSQSTKLSVVHEKKSQEGKPKEH
Sbjct: 1 MNPTETKA----------------------VKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 38
Query: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 39 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 98
Query: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 99 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 158
Query: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT
Sbjct: 159 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 218
Query: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 383
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 219 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 278
Query: 384 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 443
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 279 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 338
Query: 444 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 503
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 339 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 398
Query: 504 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 563
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 399 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 458
Query: 564 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 623
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 459 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 518
Query: 624 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 683
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 519 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 578
Query: 684 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 743
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 579 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 638
Query: 744 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 639 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 686
Score = 221 bits (564), Expect = 2e-57
Identities = 196/668 (29%), Positives = 315/668 (47%), Gaps = 71/668 (10%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 59 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 118
Query: 72 SASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVH 131
+ S S M+ I + GP ++ ++ T PE + +
Sbjct: 119 ESKPDKPSGKSGMDAALDDLI---DTLGGP----EETEEENTTYTGPEVSDPMSSTYIEE 171
Query: 132 EKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMIS 191
K + P ++ E L K+ TG P S++P P D I
Sbjct: 172 LGKREVTIPPKYRE--LLAKKEGITG-----------------PPADSSKP-IGPDDAID 211
Query: 192 A-GGESVAGITAISGKPGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDD 242
A + G +GK +K++ + ++ A P + K K + D AL+
Sbjct: 212 ALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA 271
Query: 243 LIDTLGGPEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--I 298
L +L G + E E + EV + + +E+ G+ + TIP +YR + K+G +
Sbjct: 272 LSASL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL 330
Query: 299 TGPPADSSKPIGPDDAIDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSA 348
P + KP + ID LS DF P+ +KTE+ ++ +E + S
Sbjct: 331 LPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSM 390
Query: 349 GTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKL 408
+++SA P + K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE
Sbjct: 391 CSIQSAPP----EPATLKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDR 445
Query: 409 EKCGEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEK 467
EK GE +ETIP +YRL+ DKDGKPLLP E +E+ P SE L+D LSEDF +
Sbjct: 446 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ---- 501
Query: 468 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGK 526
+ + K E++K A A +SE V +T + Q+ APP + DDA++ L+DSLG+
Sbjct: 502 -NASSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQ 558
Query: 527 KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKE 584
++ DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+YR + KP+ P K+S++
Sbjct: 559 RQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 618
Query: 585 QLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTS 644
P + +DALS D + + AK + S+ P + +A + T
Sbjct: 619 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 678
Query: 645 QSDKDLDD 652
++ K DD
Sbjct: 679 ETSKPKDD 686
Score = 80.9 bits (198), Expect = 4e-15
Identities = 100/387 (25%), Positives = 162/387 (41%), Gaps = 51/387 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 331 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 388
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 389 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 445
Query: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
EK + + + E K ++GKP LPK+ +K+ + +E
Sbjct: 446 EKLGEKEETIPPDYRLEEVKDKDGKP-------LLPKE----------SKEQLPPMSEDF 488
Query: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGK 233
+ +E + PQ+ S E AIS E S TPA ++ P + + +
Sbjct: 489 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSQ 540
Query: 234 S--GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYREL 291
S +D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR L
Sbjct: 541 SDKDLDDALDKLSDSLGQRQPDPDENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHL 599
Query: 292 LAK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLK 344
L ++ PP DS KP D IDALS D +C S T + T K++ +
Sbjct: 600 LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAAS 659
Query: 345 AQSA----GTVRSAAPPQEKKRKVEKD 367
+ A G + +A E+ K + D
Sbjct: 660 SSKAPKNGGKAKDSAKTTEETSKPKDD 686
>gi|109637769 calpastatin isoform k [Homo sapiens]
Length = 673
Score = 1311 bits (3394), Expect = 0.0
Identities = 673/708 (95%), Positives = 673/708 (95%), Gaps = 35/708 (4%)
Query: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
MNPTETKA VKTEPEKKSQSTKLSVVHEKKSQEGKPKEH
Sbjct: 1 MNPTETKA----------------------VKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 38
Query: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 39 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 98
Query: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 99 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 158
Query: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
EVSDPMSSTYIEELGKREVTIPPKYRELLAK PIGPDDAIDALSSDFT
Sbjct: 159 EVSDPMSSTYIEELGKREVTIPPKYRELLAK-------------PIGPDDAIDALSSDFT 205
Query: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 383
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 206 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 265
Query: 384 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 443
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 266 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 325
Query: 444 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 503
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 326 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 385
Query: 504 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 563
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 386 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 445
Query: 564 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 623
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 446 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 505
Query: 624 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 683
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 506 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 565
Query: 684 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 743
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 566 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 625
Query: 744 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 626 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 673
Score = 219 bits (559), Expect = 6e-57
Identities = 195/665 (29%), Positives = 314/665 (47%), Gaps = 78/665 (11%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASS 75
+ A +R + SEK++E +KP + + G S ++A S
Sbjct: 59 KKAVSRSAEQQPSEKSTEPKTKPQD-------------------MISAGGESVAGITAIS 99
Query: 76 GATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKS 135
G + T A+PV + P P+ K A+ + + +
Sbjct: 100 GKPGDKKKEKKSLTPAVPVESK---PDKPSGKSGMDAAL---------DDLIDTLGGPEE 147
Query: 136 QEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK-TKPQDMISA-G 193
E + +T P + SD S+ + ++ R P + K P D I A
Sbjct: 148 TEEENTTYTGP-----EVSDPMSS-TYIEELGKREVTIPPKYRELLAKPIGPDDAIDALS 201
Query: 194 GESVAGITAISGKPGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDDLID 245
+ G +GK +K++ + ++ A P + K K + D AL+ L
Sbjct: 202 SDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSA 261
Query: 246 TLGGPEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGP 301
+L G + E E + EV + + +E+ G+ + TIP +YR + K+G +
Sbjct: 262 SL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPE 320
Query: 302 PADSSKPIGPDDAIDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSAGTV 351
P + KP + ID LS DF P+ +KTE+ ++ +E + S ++
Sbjct: 321 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 380
Query: 352 RSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKC 411
+SA P + K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE EK
Sbjct: 381 QSAPP----EPATLKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKL 435
Query: 412 GEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSK 470
GE +ETIP +YRL+ DKDGKPLLP E +E+ P SE L+D LSEDF + +
Sbjct: 436 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NA 490
Query: 471 PTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEA 529
+ K E++K A A +SE V +T + Q+ APP + DDA++ L+DSLG+++
Sbjct: 491 SSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQP 548
Query: 530 DPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLP 587
DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+YR + KP+ P K+S++
Sbjct: 549 DPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKK 608
Query: 588 PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 647
P + +DALS D + + AK + S+ P + +A + T ++
Sbjct: 609 PADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETS 668
Query: 648 KDLDD 652
K DD
Sbjct: 669 KPKDD 673
Score = 80.9 bits (198), Expect = 4e-15
Identities = 100/387 (25%), Positives = 162/387 (41%), Gaps = 51/387 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 318 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 375
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 376 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 432
Query: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
EK + + + E K ++GKP LPK+ +K+ + +E
Sbjct: 433 EKLGEKEETIPPDYRLEEVKDKDGKP-------LLPKE----------SKEQLPPMSEDF 475
Query: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGK 233
+ +E + PQ+ S E AIS E S TPA ++ P + + +
Sbjct: 476 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSQ 527
Query: 234 S--GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYREL 291
S +D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR L
Sbjct: 528 SDKDLDDALDKLSDSLGQRQPDPDENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHL 586
Query: 292 LAK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLK 344
L ++ PP DS KP D IDALS D +C S T + T K++ +
Sbjct: 587 LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAAS 646
Query: 345 AQSA----GTVRSAAPPQEKKRKVEKD 367
+ A G + +A E+ K + D
Sbjct: 647 SSKAPKNGGKAKDSAKTTEETSKPKDD 673
>gi|109637767 calpastatin isoform j [Homo sapiens]
Length = 667
Score = 1297 bits (3357), Expect = 0.0
Identities = 667/708 (94%), Positives = 667/708 (94%), Gaps = 41/708 (5%)
Query: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
MNPTETKA VKTEPEKKSQSTK
Sbjct: 1 MNPTETKA----------------------VKTEPEKKSQSTK----------------- 21
Query: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 22 --PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 79
Query: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 80 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 139
Query: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT
Sbjct: 140 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 199
Query: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 383
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 200 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 259
Query: 384 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 443
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 260 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 319
Query: 444 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 503
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 320 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 379
Query: 504 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 563
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 380 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 439
Query: 564 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 623
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 440 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 499
Query: 624 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 683
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 500 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 559
Query: 684 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 743
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 560 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 619
Query: 744 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 620 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 667
Score = 221 bits (564), Expect = 2e-57
Identities = 196/668 (29%), Positives = 315/668 (47%), Gaps = 71/668 (10%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASL----GSSQSSRTYAGGTASATKV 71
+ A +R + SEK++E +KP + + + A + G + A V
Sbjct: 40 KKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPV 99
Query: 72 SASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVH 131
+ S S M+ I + GP ++ ++ T PE + +
Sbjct: 100 ESKPDKPSGKSGMDAALDDLI---DTLGGP----EETEEENTTYTGPEVSDPMSSTYIEE 152
Query: 132 EKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMIS 191
K + P ++ E L K+ TG P S++P P D I
Sbjct: 153 LGKREVTIPPKYRE--LLAKKEGITG-----------------PPADSSKP-IGPDDAID 192
Query: 192 A-GGESVAGITAISGKPGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDD 242
A + G +GK +K++ + ++ A P + K K + D AL+
Sbjct: 193 ALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA 252
Query: 243 LIDTLGGPEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--I 298
L +L G + E E + EV + + +E+ G+ + TIP +YR + K+G +
Sbjct: 253 LSASL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL 311
Query: 299 TGPPADSSKPIGPDDAIDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSA 348
P + KP + ID LS DF P+ +KTE+ ++ +E + S
Sbjct: 312 LPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSM 371
Query: 349 GTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKL 408
+++SA P + K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE
Sbjct: 372 CSIQSAPP----EPATLKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDR 426
Query: 409 EKCGEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEK 467
EK GE +ETIP +YRL+ DKDGKPLLP E +E+ P SE L+D LSEDF +
Sbjct: 427 EKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ---- 482
Query: 468 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGK 526
+ + K E++K A A +SE V +T + Q+ APP + DDA++ L+DSLG+
Sbjct: 483 -NASSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQ 539
Query: 527 KEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKE 584
++ DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+YR + KP+ P K+S++
Sbjct: 540 RQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 599
Query: 585 QLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTS 644
P + +DALS D + + AK + S+ P + +A + T
Sbjct: 600 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 659
Query: 645 QSDKDLDD 652
++ K DD
Sbjct: 660 ETSKPKDD 667
Score = 80.9 bits (198), Expect = 4e-15
Identities = 100/387 (25%), Positives = 162/387 (41%), Gaps = 51/387 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 312 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 369
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 370 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 426
Query: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
EK + + + E K ++GKP LPK+ +K+ + +E
Sbjct: 427 EKLGEKEETIPPDYRLEEVKDKDGKP-------LLPKE----------SKEQLPPMSEDF 469
Query: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGK 233
+ +E + PQ+ S E AIS E S TPA ++ P + + +
Sbjct: 470 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSQ 521
Query: 234 S--GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYREL 291
S +D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR L
Sbjct: 522 SDKDLDDALDKLSDSLGQRQPDPDENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHL 580
Query: 292 LAK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLK 344
L ++ PP DS KP D IDALS D +C S T + T K++ +
Sbjct: 581 LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAAS 640
Query: 345 AQSA----GTVRSAAPPQEKKRKVEKD 367
+ A G + +A E+ K + D
Sbjct: 641 SSKAPKNGGKAKDSAKTTEETSKPKDD 667
>gi|109637771 calpastatin isoform l [Homo sapiens]
Length = 654
Score = 1262 bits (3265), Expect = 0.0
Identities = 654/708 (92%), Positives = 654/708 (92%), Gaps = 54/708 (7%)
Query: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
MNPTETKA VKTEPEKKSQSTK
Sbjct: 1 MNPTETKA----------------------VKTEPEKKSQSTK----------------- 21
Query: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI
Sbjct: 22 --PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 79
Query: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP
Sbjct: 80 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 139
Query: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
EVSDPMSSTYIEELGKREVTIPPKYRELLAK PIGPDDAIDALSSDFT
Sbjct: 140 EVSDPMSSTYIEELGKREVTIPPKYRELLAK-------------PIGPDDAIDALSSDFT 186
Query: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 383
CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT
Sbjct: 187 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGT 246
Query: 384 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 443
RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP
Sbjct: 247 RQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKP 306
Query: 444 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 503
KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP
Sbjct: 307 KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPP 366
Query: 504 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 563
EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD
Sbjct: 367 EPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPD 426
Query: 564 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 623
YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS
Sbjct: 427 YRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAIS 486
Query: 624 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 683
EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK
Sbjct: 487 EVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAK 546
Query: 684 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 743
AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS
Sbjct: 547 AEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDS 606
Query: 744 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 607 CPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 654
Score = 219 bits (559), Expect = 6e-57
Identities = 195/665 (29%), Positives = 314/665 (47%), Gaps = 78/665 (11%)
Query: 16 RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASS 75
+ A +R + SEK++E +KP + + G S ++A S
Sbjct: 40 KKAVSRSAEQQPSEKSTEPKTKPQD-------------------MISAGGESVAGITAIS 80
Query: 76 GATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKS 135
G + T A+PV + P P+ K A+ + + +
Sbjct: 81 GKPGDKKKEKKSLTPAVPVESK---PDKPSGKSGMDAAL---------DDLIDTLGGPEE 128
Query: 136 QEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK-TKPQDMISA-G 193
E + +T P + SD S+ + ++ R P + K P D I A
Sbjct: 129 TEEENTTYTGP-----EVSDPMSS-TYIEELGKREVTIPPKYRELLAKPIGPDDAIDALS 182
Query: 194 GESVAGITAISGKPGDKKKEKK--------SLTPAVPVESKPDKPSGKSGMDAALDDLID 245
+ G +GK +K++ + ++ A P + K K + D AL+ L
Sbjct: 183 SDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSA 242
Query: 246 TLGGPEETEEENTTYTGPEVSDPMS-STYIEELGKREVTIPPKYR-ELLAKKEG--ITGP 301
+L G + E E + EV + + +E+ G+ + TIP +YR + K+G +
Sbjct: 243 SL-GTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPE 301
Query: 302 PADSSKPIGPDDAIDALSSDFTCG----SPTAAGKKTEKEES------TEVLKAQSAGTV 351
P + KP + ID LS DF P+ +KTE+ ++ +E + S ++
Sbjct: 302 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 361
Query: 352 RSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKC 411
+SA P + K T+ D A+EAL+ SLG ++A+PE D + + + + KAKEE EK
Sbjct: 362 QSAPP----EPATLKGTVPDDAVEALADSLGKKEADPE-DGKPVMDKVKEKAKEEDREKL 416
Query: 412 GEDDETIPSEYRLKPATDKDGKPLLP-EPEEKPKPRSESELIDELSEDFDRSECKEKPSK 470
GE +ETIP +YRL+ DKDGKPLLP E +E+ P SE L+D LSEDF + +
Sbjct: 417 GEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQ-----NA 471
Query: 471 PTEKTEESKAAAPAPVSEAVCRTSMCSIQS-APPEPATLKGTVPDDAVEALADSLGKKEA 529
+ K E++K A A +SE V +T + Q+ APP + DDA++ L+DSLG+++
Sbjct: 472 SSLKFEDAKLA--AAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQP 529
Query: 530 DPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP--KESKEQLP 587
DP++ KP+ DKVKEKAK E R+KLGE+++TIPP+YR + KP+ P K+S++
Sbjct: 530 DPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKK 589
Query: 588 PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 647
P + +DALS D + + AK + S+ P + +A + T ++
Sbjct: 590 PADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETS 649
Query: 648 KDLDD 652
K DD
Sbjct: 650 KPKDD 654
Score = 80.9 bits (198), Expect = 4e-15
Identities = 100/387 (25%), Positives = 162/387 (41%), Gaps = 51/387 (13%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 299 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 356
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 357 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 413
Query: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
EK + + + E K ++GKP LPK+ +K+ + +E
Sbjct: 414 EKLGEKEETIPPDYRLEEVKDKDGKP-------LLPKE----------SKEQLPPMSEDF 456
Query: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES-KPDKPSGK 233
+ +E + PQ+ S E AIS E S TPA ++ P + + +
Sbjct: 457 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSQ 508
Query: 234 S--GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYREL 291
S +D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR L
Sbjct: 509 SDKDLDDALDKLSDSLGQRQPDPDENKPME-DKVKEKAKAEHRDKLGERDDTIPPEYRHL 567
Query: 292 LAK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLK 344
L ++ PP DS KP D IDALS D +C S T + T K++ +
Sbjct: 568 LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAAS 627
Query: 345 AQSA----GTVRSAAPPQEKKRKVEKD 367
+ A G + +A E+ K + D
Sbjct: 628 SSKAPKNGGKAKDSAKTTEETSKPKDD 654
>gi|27765087 calpastatin isoform c [Homo sapiens]
Length = 430
Score = 781 bits (2017), Expect = 0.0
Identities = 391/393 (99%), Positives = 392/393 (99%), Gaps = 1/393 (0%)
Query: 399 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 458
D+AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED
Sbjct: 39 DQAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 98
Query: 459 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 518
FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE
Sbjct: 99 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 158
Query: 519 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 578
ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL
Sbjct: 159 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 218
Query: 579 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 638
PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA
Sbjct: 219 PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGA 278
Query: 639 PPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 698
PPRDTS SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP
Sbjct: 279 PPRDTS-SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIP 337
Query: 699 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 758
PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK
Sbjct: 338 PEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDK 397
Query: 759 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD
Sbjct: 398 CKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
Score = 206 bits (525), Expect = 5e-53
Identities = 144/396 (36%), Positives = 213/396 (53%), Gaps = 30/396 (7%)
Query: 274 IEELGKREVTIPPKYR-ELLAKKEG--ITGPPADSSKPIGPDDAIDALSSDFTCGSPTAA 330
+E+ G+ + TIP +YR + K+G + P + KP + ID LS DF
Sbjct: 48 LEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSE--CK 105
Query: 331 GKKTEKEESTEVLKAQSAGTVRSA-----------APPQEKKRKVEKDTMSDQALEALSA 379
K ++ E TE KA + V A APP+ K T+ D A+EAL+
Sbjct: 106 EKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLK---GTVPDDAVEALAD 162
Query: 380 SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLP-E 438
SLG ++A+PE D + + + + KAKEE EK GE +ETIP +YRL+ DKDGKPLLP E
Sbjct: 163 SLGKKEADPE-DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE 221
Query: 439 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 498
+E+ P SE L+D LSEDF + + + K E++K A A +SE V +T +
Sbjct: 222 SKEQLPPMSEDFLLDALSEDFSGPQ-----NASSLKFEDAKLA--AAISEVVSQTPASTT 274
Query: 499 QSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEE 558
Q+ P T DDA++ L+DSLG+++ DP++ KP+ DKVKEKAK E R+KLGE+++
Sbjct: 275 QAGAPPRDTSSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDD 334
Query: 559 TIPPDYRLEEVKDKDGKPLLP--KESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDA 616
TIPP+YR + KP+ P K+S++ P + +DALS D + + A
Sbjct: 335 TIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTA 394
Query: 617 KLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDD 652
K + S+ P + +A + T ++ K DD
Sbjct: 395 KDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 430
Score = 82.8 bits (203), Expect = 1e-15
Identities = 100/386 (25%), Positives = 159/386 (41%), Gaps = 50/386 (12%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P +KP PR + + + E PSKP EK + A + S RT
Sbjct: 76 LPEPEEKP--KPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 133
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPH--LPNKKKHKKQAVKTEP 118
SA A+ T ++ E A + ++ P P K K++A + +
Sbjct: 134 SMCSIQSAPPEPATLKGTVPDDAV---EALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 190
Query: 119 EKKSQSTKLSV----VHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQ 174
EK + + + E K ++GKP LPK++ K+ + +E
Sbjct: 191 EKLGEKEETIPPDYRLEEVKDKDGKPL-------LPKES----------KEQLPPMSEDF 233
Query: 175 PSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVES--KPDKPSG 232
+ +E + PQ+ S E AIS E S TPA ++ P S
Sbjct: 234 LLDALSEDFSGPQNASSLKFEDAKLAAAIS--------EVVSQTPASTTQAGAPPRDTSS 285
Query: 233 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELL 292
+D ALD L D+LG + +EN +V + + + ++LG+R+ TIPP+YR LL
Sbjct: 286 DKDLDDALDKLSDSLGQRQPDPDENKPMED-KVKEKAKAEHRDKLGERDDTIPPEYRHLL 344
Query: 293 AK--KEGITGPPA----DSSKPIGPDDAIDALSSDF-TCGSPTAAGKKTEKEESTEVLKA 345
++ PP DS KP D IDALS D +C S T + T K++ + +
Sbjct: 345 DDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASS 404
Query: 346 QSA----GTVRSAAPPQEKKRKVEKD 367
A G + +A E+ K + D
Sbjct: 405 SKAPKNGGKAKDSAKTTEETSKPKDD 430
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 92.8 bits (229), Expect = 1e-18
Identities = 155/657 (23%), Positives = 257/657 (39%), Gaps = 85/657 (12%)
Query: 92 IPVSQQMEGPHLPNKKKHKKQAVKTEPEKK--SQSTKLSVVHEKKSQEGKPKEHTEPKSL 149
IP S P +P+ H K VK+E + K +S K +V+ E++++E + E +
Sbjct: 418 IPFSLPEGLPKIPSVSTHIK--VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEE 475
Query: 150 PKQASDTGSNDAHNKKAVSRSAEQQ----PSEKSTEPKTKPQDMISAGGESVAGITAISG 205
+ + G + ++ + E++ P+E++ P+ + + + +S A
Sbjct: 476 KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPA-----EA 530
Query: 206 KPGDKKKEKKSLTPAVPVESK-PDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE 264
K +K++ K P ++K P K KS +A PE+ E ++ E
Sbjct: 531 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK---------SPEKEEAKSPA----E 577
Query: 265 VSDP--MSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDA-LSSD 321
V P S EE P+ + K+E + PA++ P+ + A + S
Sbjct: 578 VKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKS--PAEAKSPVKEEAKSPAEVKSP 635
Query: 322 FTCGSPTAA-GKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSAS 380
SPT K EK +S E +A+S +S + K + K + +A A
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 381 LGTRQA--EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPE 438
++ PE +KE EAK+ E+ E+ +T E P ++ P
Sbjct: 696 SPVKEEAKSPEKAKSPVKE--EAKSPEKAKSPVKEEAKT--PEKAKSPVKEEAKSP---- 747
Query: 439 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 498
EK K +++ +D S + ++ KE+ P +K E A +PV E V
Sbjct: 748 --EKAKSPEKAKTLDVKSPEA-KTPAKEEARSPADKFPEK---AKSPVKEEV-------- 793
Query: 499 QSAPPEPATLKGTVPDDAVEALADSLGKKEADP----EDGKPVMDKVKEKAKEEDREKLG 554
P K + +DA +A + KKE E+ KP KVKE K+ + EK
Sbjct: 794 ----KSPEKAKSPLKEDA-KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA- 847
Query: 555 EKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE 614
P + EE KD K PK KE P E+ A+ + A + E
Sbjct: 848 ------PATPKTEEKKDSK-KEEAPK--KEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898
Query: 615 DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM 674
D K E + + P T + K+ DDA K +++ E K
Sbjct: 899 DKKKVPT-PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT 957
Query: 675 --------EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSED 723
E+K K +AKA+ DK ++ + P + + K KPP K +ED
Sbjct: 958 KEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 91.3 bits (225), Expect = 3e-18
Identities = 138/596 (23%), Positives = 225/596 (37%), Gaps = 57/596 (9%)
Query: 219 PAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELG 278
P +P S K + + +T+ E+TEE T EV++ EE G
Sbjct: 427 PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVT---EEVTEEEEKEAKEEEG 483
Query: 279 KREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEE 338
K E + E +E PPA+ + P+ +A S A K EKEE
Sbjct: 484 KEEEG--GEEEEAEGGEEETKSPPAEEAA--SPEK--EAKSPVKEEAKSPAEAKSPEKEE 537
Query: 339 STEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEV 398
+ + +S +S A + K K ++A + P + K
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE--EAKSP 595
Query: 399 DEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSED 458
EAK+ E+ E+ ++ P+E + + + PE+ P E E ++
Sbjct: 596 AEAKSPEKAKSPVKEEAKS-PAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 459 FDRSECK--EKPSKPTEKTEESKAAAPAPV-SEAVCRTSMCS-IQSAPPEPATLKGTVPD 514
++ E K EK P + +S A +PV +EA S ++ P K V +
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 515 DAVEA-LADSLGKKEAD-PEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDK 572
+A A S K+EA PE K VKE+AK ++ K EK +T+ +VK
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAK---SPVKEEAKSPEKAKSPEKAKTL-------DVKSP 764
Query: 573 DGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAA--------AISE 624
+ K +E++ E + E+ P+ A S EDAK S
Sbjct: 765 EAKTPAKEEARSPADKFPEK-AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 625 VVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKA-- 682
V + + PP+ + ++ DS + P + KP ++ KE A
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE 883
Query: 683 -----KAEHRDKLGERDDTIP-PEYRHLLDDNGQDKPVKPPTKKSEDSKKPAD--DQDPI 734
K E + + E +P PE ++ P K K+ K+ + ++P
Sbjct: 884 KPKESKVEAKKEEAEDKKKVPTPE---------KEAPAKVEVKEDAKPKEKTEVAKKEPD 934
Query: 735 DALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKT-TEETSKPK 789
DA + + E + K +KA + PK KAK+ KT ++E SKPK
Sbjct: 935 DAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPK 990
Score = 91.3 bits (225), Expect = 3e-18
Identities = 127/584 (21%), Positives = 218/584 (37%), Gaps = 79/584 (13%)
Query: 23 THEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSS 82
T E E+ E+ + G+++ E++ A G ++ A AS K + S K
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP---VKEE 523
Query: 83 SMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKE 142
+ +P E K+ P K++ K A PEK K K E K E
Sbjct: 524 AKSPAEAKS------------PEKEEAKSPAEVKSPEKAKSPAKEEA---KSPPEAKSPE 568
Query: 143 HTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 202
E KS P + + K+ AE + EK+ P ++ + E+ + +
Sbjct: 569 KEEAKS-PAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPV---KEEAKSPAEAKSPVKE 624
Query: 203 ISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 262
+ P + K +K+ +P P+K +A PE+ +
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAK---------SPEKAKS------- 668
Query: 263 PEVSDPMSSTYIEELGKREVTIPPK----YRELLAKKEGITGPPADSSKPIGPDDAIDAL 318
P ++ S + K E P K +E E P + +K P+ A +
Sbjct: 669 PVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK--SPEKAKSPV 726
Query: 319 SSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALS 378
+ + K E + + + A T+ +P + K E + +D+ E
Sbjct: 727 KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK 786
Query: 379 ASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE-----DDETIPSEYRLKPATDK--- 430
+ + PE +KE +AKA E+++ K E +E P E ++K K
Sbjct: 787 SPVKEEVKSPEKAKSPLKE--DAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEE 844
Query: 431 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 490
+ P P+ EEK + E + ++ + + +EK EK +ESK
Sbjct: 845 EKAPATPKTEEKKDSKKE----EAPKKEAPKPKVEEKKEPAVEKPKESKV---------- 890
Query: 491 CRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDR 550
A E A K VP EA A K++A P++ V K + AK ++
Sbjct: 891 ---------EAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 551 EKLGEKEETIP--PDYRLEEVKDKDGKPLLPKESKEQLPPMSED 592
K EK+E P D + E+ K + KP ++KE +S++
Sbjct: 942 SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985
Score = 85.1 bits (209), Expect = 2e-16
Identities = 122/528 (23%), Positives = 208/528 (39%), Gaps = 67/528 (12%)
Query: 288 YRELLAKKEGITG-PPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQ 346
YR+LL +E G P S P G I ++S+ S + E+ T +++ Q
Sbjct: 402 YRKLLEGEECRIGFGPIPFSLPEGLPK-IPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQ 460
Query: 347 SAGT-VRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQ---------AEPELDLRS-I 395
+ T V +E+K E++ ++ E A G + A PE + +S +
Sbjct: 461 TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV 520
Query: 396 KEVDE--AKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELID 453
KE + A+AK + E+ E E PA ++ P + EK + +S +E+
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV-- 578
Query: 454 ELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVP 513
S + +S KE+ P E KA +P ++ PA K V
Sbjct: 579 -KSPEKAKSPAKEEAKSPAEAKSPEKAKSP--------------VKEEAKSPAEAKSPVK 623
Query: 514 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKD 573
++A K A+ + + KE+AK ++ K EKEE P+ VK +
Sbjct: 624 EEA---------KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA 674
Query: 574 GKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAST 633
P K S + S + + E+ P+ A S E+AK V + +
Sbjct: 675 KSPEKAK-SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP 733
Query: 634 TQAGAPPRDTSQSD---------KDLDDALDKLSDSLGQRQPDPDENKPMEDK--VKEKA 682
+A +P ++ ++S K LD + + P + P + K VKE+
Sbjct: 734 EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Query: 683 KAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLD 742
K+ + K ++D PE + + + VK P K+ E ++ + P A + +
Sbjct: 794 KSPEKAKSPLKEDAKAPE-----KEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA---EEE 845
Query: 743 SCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 790
P+T +T + KD K+ A +AP K K K KPK+
Sbjct: 846 KAPATPKTEEK--KDSKKEEAPKKEAP----KPKVEEKKEPAVEKPKE 887
Score = 78.6 bits (192), Expect = 2e-14
Identities = 114/521 (21%), Positives = 199/521 (38%), Gaps = 44/521 (8%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
P ++ A SP ++ K+ E P +++ +A S ++
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV 578
Query: 64 GTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGP---HLPNKKKHKKQAVKTEPEK 120
+ K A A S + + +P + K+ PV ++ + P P K++ K A PEK
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSPEKAKS-PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637
Query: 121 KSQSTKLSVVHEKKSQEGKPKEHTEP---KSLPKQASDTGSNDAHNKKAVSRSAEQQPSE 177
TK +K++ + +E P KS K + + KA ++S E+ S
Sbjct: 638 AKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSP 697
Query: 178 KSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMD 237
E K+ + E+ + A S + K +K+ +P P+K KS
Sbjct: 698 VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK--AKSPEK 755
Query: 238 A-ALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLA--- 293
A LD P + E + PE + S EE+ E P + A
Sbjct: 756 AKTLDVKSPEAKTPAKEEARSPADKFPEKA---KSPVKEEVKSPEKAKSPLKEDAKAPEK 812
Query: 294 ---KKEGITGPPADSSKP--IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSA 348
KKE + P + KP + + + +P KK K+E +A
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Query: 349 GTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKL 408
P EK ++ + + ++A + ++A +++++ ++AK KE K
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK-----EDAKPKE-KT 926
Query: 409 EKCGEDDETIPSEYRLKPATDKDGKPLLPEP-EEKPKPRSESELIDELSEDFDRSECKEK 467
E ++ + ++ KPA K+ P + EEK K E + +++ D++ KE
Sbjct: 927 EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE- 985
Query: 468 PSKPT-EKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPAT 507
PSKP EK E+S +S S PPE AT
Sbjct: 986 PSKPKAEKAEKS--------------SSTDQKDSKPPEKAT 1012
Score = 75.5 bits (184), Expect = 2e-13
Identities = 101/498 (20%), Positives = 182/498 (36%), Gaps = 53/498 (10%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
P ++ A SP ++ K+ E P +++ +A S ++S
Sbjct: 553 PAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEA 612
Query: 64 GTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQ 123
+ + K A S + +P + K+ P ++ + P K K ++ PEK
Sbjct: 613 KSPAEAKSPVKEEAKSPAEVKSPEKAKS-PTKEEAKSPE---KAKSPEKEEAKSPEKAKS 668
Query: 124 STKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK 183
K K ++ K E KS K S +KA S E+ S + +
Sbjct: 669 PVK---AEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 184 TKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDL 243
K + +S A S + ++ K+L P P K +S D
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKF---- 781
Query: 244 IDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPA 303
PE+ + P + S + K + P K + KKE + P
Sbjct: 782 ------PEKAK-------SPVKEEVKSPEKAKSPLKEDAKAPEKE---IPKKEEVKSPVK 825
Query: 304 DSSKP--IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKK 361
+ KP + + + +P KK K+E +A P EK
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Query: 362 RKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSE 421
++ + + ++A + ++A +++++ ++AK K EK E ++ + ++
Sbjct: 886 KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVK-----EDAKPK-EKTEVAKKEPDDAKAK 939
Query: 422 YRLKPATDKDGKP--------LLPEPEEKPKPRSESELIDE-LSEDFDR---------SE 463
KPA K+ P +PEEKPK ++++ D+ LS++ + S
Sbjct: 940 EPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSS 999
Query: 464 CKEKPSKPTEKTEESKAA 481
+K SKP EK E KAA
Sbjct: 1000 TDQKDSKPPEKATEDKAA 1017
Score = 47.8 bits (112), Expect = 4e-05
Identities = 59/270 (21%), Positives = 103/270 (38%), Gaps = 46/270 (17%)
Query: 533 DGKPVMDKVKE--KAKEEDREKLGEK--------EETIPPDYRLEEVKDKDGKPLLPKES 582
+G P + V K K E++ K+ EK EE EEV +++ K +E
Sbjct: 424 EGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEG 483
Query: 583 KEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD 642
KE+ E E G + S E+A + +A +P ++
Sbjct: 484 KEEEGGEEE--------EAEGGEEETKSPPAEEAA-------------SPEKEAKSPVKE 522
Query: 643 TSQSDKDLDDALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEY 701
++S + + P+ +E K P E K EKAK+ +++ + PE
Sbjct: 523 EAKSPAEA-------------KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEK 569
Query: 702 RHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKK 761
P K + E++K PA+ + P A S + S E +++ K++ K
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAE-AKSPVKEEAKS 628
Query: 762 AASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
A K K+ AK+ E+ P+ +
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKE 658
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 72.8 bits (177), Expect = 1e-12
Identities = 163/845 (19%), Positives = 296/845 (35%), Gaps = 114/845 (13%)
Query: 5 GQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG- 63
G P+ S +R++ + H S++TS S G + + S SSR
Sbjct: 112 GPAPSTSQSQKRSSGLQSGHS--SQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQH 169
Query: 64 GTASATKVSASSGATSKSSSMNPTETKA------IPVSQQMEGPHLPNKKKHKKQAVK-T 116
G+ + S+S G SS+N + +++ Q+ + P P+ V +
Sbjct: 170 GSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFS 229
Query: 117 EPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKS-----LPKQASDTGSNDAHNKKAVSRSA 171
+ +QS S++ + S KP + P PK +S+ S+ +H
Sbjct: 230 SGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMT---- 285
Query: 172 EQQPSEKS--TEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDK 229
E +PS K+ T+ K Q + ++ V+ + I K+ S P + P K
Sbjct: 286 ELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEIL------KEMTHSWPPPLTAIHTPCK 339
Query: 230 PSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYR 289
+ G E+ Y + S+ S + + + +
Sbjct: 340 TEPSKFPFPTKESQQSNFGTGEQKR-----YNPSKTSNGHQSKSMLKDDLKLSSSEDSDG 394
Query: 290 ELLAKKEGITGPPADSSKPI-----GPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLK 344
E K P +S+P G D++ D SS GS +++G +E E S+ +
Sbjct: 395 EQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSH--SGSESSSGSDSESESSSSDSE 452
Query: 345 AQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAK 404
A S P K + D ++ + + P + S + K
Sbjct: 453 ANEPSQSASPEPEPPPTNKWQLDNWLNK--------VNPHKVSPASSVDSNIPSSQGYKK 504
Query: 405 EEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSEC 464
E + + G TD G P+ P +S+ I + SE +
Sbjct: 505 EGREQGTGNS------------YTDTSG----PKETSSATPGRDSKTIQKGSESGRGRQK 548
Query: 465 KEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSL 524
S T + P +A ++ P L ++P +A
Sbjct: 549 SPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS 608
Query: 525 GK---KEADPEDGKPVMDKVKEKAKEEDREKLGE------------KEETIPPDYRLEEV 569
K K+ +P +K K K+ + +K E + E++PP + +
Sbjct: 609 RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKY 668
Query: 570 KDKDGKPLLPKESKEQ--------LPPMSEDFLLDALSEDFSGPQNASSL--KFEDAKLA 619
+ + P+ P +E+ PM E LL LSE P + L K + L
Sbjct: 669 PESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSE----PDDRYPLIVKIDLNLLT 724
Query: 620 AAISEVVSQT-PASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKV 678
+ +T P + P + T ++ K A +K+S+ ++ + D+N+ E K
Sbjct: 725 RIPGKPYKETEPPKGEKKNVPEKHTREAQKQ---ASEKVSNKGKRKHKNEDDNRASESK- 780
Query: 679 KEKAKAEHRDKLGERDDT-------IPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQ 731
K K E ++ G + + + + LL P K P + K+
Sbjct: 781 --KPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQS 838
Query: 732 DPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSS-------KAPKNGGKAKDSAKTTEE 784
+ + S +++ S +T+K K + +SS KAP + SA T +
Sbjct: 839 SSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTL-D 897
Query: 785 TSKPK 789
+SKP+
Sbjct: 898 SSKPR 902
Score = 35.4 bits (80), Expect = 0.21
Identities = 147/779 (18%), Positives = 252/779 (32%), Gaps = 138/779 (17%)
Query: 24 HEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSS 83
H + + +P P +K+++ L S SS+ + G++S T SSG S
Sbjct: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTN---SSGQRHDRES 155
Query: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
N + + S + +G H +H K + S GKP+
Sbjct: 156 YNNSGS-----SSRKKGQH---GSEHSKS--------------------RSSSPGKPQAV 187
Query: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
+ SL S + ND H+K+ + + P P P S+G S
Sbjct: 188 S---SLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVP---FSSGQHSTQ----- 236
Query: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
S P K L KP+ + + G E E + ++
Sbjct: 237 SFPPSLMSKSNSML----------QKPTA----------YVRPMDGQESMEPKLSSEHYS 276
Query: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
S S T ++ K +T K I P D+S G +D + + T
Sbjct: 277 SQSHGNSMTELKPSSKAHLT-----------KLKIPSQPLDASAS-GDVSCVDEILKEMT 324
Query: 324 CGSP---TAAGKKTEKEES-----TEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALE 375
P TA + E S T+ + + GT ++K+ K + Q+
Sbjct: 325 HSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT------GEQKRYNPSKTSNGHQSKS 378
Query: 376 ALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPL 435
L + +L L S ++ D + + D+T+P R P ++ +
Sbjct: 379 ML---------KDDLKLSSSEDSDGEQ----------DCDKTMP---RSTPGSNSEPSHH 416
Query: 436 LPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSM 495
E + + S S E S D E S +E E S++A+P P + +
Sbjct: 417 NSEGADNSRDDSSSHSGSESSSGSDSE--SESSSSDSEANEPSQSASPEPEPPPTNKWQL 474
Query: 496 CS-IQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLG 554
+ + P + +V + + S G K+ E G KE G
Sbjct: 475 DNWLNKVNPHKVSPASSVDSN----IPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPG 530
Query: 555 EKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE 614
+TI + + G+ P +S + +E + + LK E
Sbjct: 531 RDSKTIQ-----KGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIE 585
Query: 615 DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM 674
S + S + T+ P +S K S +
Sbjct: 586 SETPVDLASSMPSSRHKAATKGSRKPNIKKES---------KSSPRPTAEKKKYKSTSKS 636
Query: 675 EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDS------KKPA 728
K +E + + + +++PP + PVKP + + EDS P
Sbjct: 637 SQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPM 696
Query: 729 DDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK 787
++++ + LS D P + N K ++ PK G K K T E K
Sbjct: 697 EEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPK-GEKKNVPEKHTREAQK 754
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 71.2 bits (173), Expect = 3e-12
Identities = 131/661 (19%), Positives = 247/661 (37%), Gaps = 121/661 (18%)
Query: 97 QMEGPHLPNKKKHKKQAVKTE-PEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASD 155
+++ P L K+ HK + K E PE+K Q+ EK ++ + KE E K+ K+ +
Sbjct: 132 EIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIE 191
Query: 156 TGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKK 215
+ K +++ ++ + + +E KTK + K G ++K K+
Sbjct: 192 --KKEKPETKTLAKEQKKAKTAEKSEEKTKKEV-----------------KGGKQEKVKQ 232
Query: 216 SLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMS-STYI 274
+ V+ P KP E+ ++E + E D + Y+
Sbjct: 233 TAAKVKEVQKTPSKPK-------------------EKEDKEKAAVSKHEQKDQYAFCRYM 273
Query: 275 EELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKT 334
++ + +L + PP + + P A AL KK
Sbjct: 274 IDIFV--------HGDLKPGQSPAIPPPLPTEQASRPTPASPALEEK------EGEKKKA 319
Query: 335 EKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRS 394
EK+ ++E K + ++ K+K EK+T D + + T+Q ++ ++
Sbjct: 320 EKKVTSETKKKEK----------EDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQA 369
Query: 395 IKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDE 454
+ DE K +K +K P+E ++ K EP + PK E
Sbjct: 370 AAKKDEKKEDSKKTKK--------PAEVEQPKGKKQEKKEKHVEPAKSPK--------KE 413
Query: 455 LSEDFDRS-ECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVP 513
S D+ + K + +K K A P E +T I+ K
Sbjct: 414 HSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKE-------KSGKT 466
Query: 514 DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKD 573
++ GK+E P K +K E K+E K G++ + PP +L+ K++
Sbjct: 467 SSILKDKEPIKGKEEKVPASLK---EKEPETKKDEKMSKAGKEVKPKPP--QLQGKKEEK 521
Query: 574 GKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAST 633
+P + KE+K P +SE + +D P+ S + K V+ Q A T
Sbjct: 522 PEPQIKKEAK---PAISEKVQIH--KQDIVKPEKTVSHGKPEEK-------VLKQVKAVT 569
Query: 634 TQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGER 693
+ A P+ T +++ ++ S+ +P P E K K E + E+
Sbjct: 570 IEKTAKPKPTKKAEH-----REREPPSIKTDKPKPTPKGTSEVTESGKKKTE----ISEK 620
Query: 694 DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQN 753
+ + +HL ++ + ++KPA +S D++ P++ + +
Sbjct: 621 ESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPA-------RVSKDVEDVPASKKAKEG 673
Query: 754 T 754
T
Sbjct: 674 T 674
Score = 63.9 bits (154), Expect = 5e-10
Identities = 137/622 (22%), Positives = 224/622 (36%), Gaps = 95/622 (15%)
Query: 7 KPAASPRPRRAAAARRTH-------EHVSEKTSESPSKPGEKKGSDEKK----AASLGSS 55
K +P R + TH E V EK E P K K EKK +L
Sbjct: 147 KTEKQEKPERKIQTKVTHKEKEKGKEKVREK--EKPEKKATHKEKIEKKEKPETKTLAKE 204
Query: 56 QSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVK 115
Q A + TK G K + A V + + P P +K+ K++A
Sbjct: 205 QKKAKTAEKSEEKTKKEVKGGKQEK------VKQTAAKVKEVQKTPSKPKEKEDKEKAAV 258
Query: 116 TEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAV-SRSAEQQ 174
++ E+K Q + + G K P P ++ S A+ + E++
Sbjct: 259 SKHEQKDQYAFCRYMID-IFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKK 317
Query: 175 PSEK--STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSG 232
+EK ++E K K ++ I E I +PG K E K T + ++ K
Sbjct: 318 KAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG-KASETKQGTVKIAAQAAAKK--- 373
Query: 233 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELL 292
E+ E+ T EV P ++ E PK +
Sbjct: 374 -----------------DEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSV 416
Query: 293 AKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVR 352
+ + + + IG A+ P +KT K E+ K +S T
Sbjct: 417 PSDKQVKAKTERAKEEIGAVSIKKAV--------PGKKEEKTTKTVEQEIRKEKSGKTSS 468
Query: 353 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 412
+ K K EK + ASL ++ E + D + K E K K +L+ G
Sbjct: 469 ILKDKEPIKGKEEK----------VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQ--G 516
Query: 413 EDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPT 472
+ +E + +P K+ KP + E K + + I + + + +EK K
Sbjct: 517 KKEE------KPEPQIKKEAKPAISE-----KVQIHKQDIVKPEKTVSHGKPEEKVLKQV 565
Query: 473 EKTEESKAAAPAPVSEAVCR-TSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADP 531
+ K A P P +A R SI++ P+P T KGT + E+ GKK+ +
Sbjct: 566 KAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKP-TPKGT--SEVTES-----GKKKTEI 617
Query: 532 EDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSE 591
+ + K K K EK+ ++E++ +L V K KP + E +P +
Sbjct: 618 SEKE---SKEKADMKHLREEKVSTRKESL----QLHNV-TKAEKPARVSKDVEDVPASKK 669
Query: 592 DFLLDALSEDFSGPQNASSLKF 613
+ED S + S + F
Sbjct: 670 ---AKEGTEDVSPTKQKSPISF 688
Score = 62.4 bits (150), Expect = 2e-09
Identities = 99/457 (21%), Positives = 163/457 (35%), Gaps = 94/457 (20%)
Query: 3 QPGQKPAASPRPRRAAAARRTHEHVSEKTSESPS---KPGEKKGSDEKKAASLGSSQSSR 59
+PGQ PA P E S T SP+ K GEKK + EKK S +
Sbjct: 283 KPGQSPAIPP--------PLPTEQASRPTPASPALEEKEGEKKKA-EKKVTSETKKKEKE 333
Query: 60 TYAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPE 119
+ T + K+S K + + + KK KK A +P+
Sbjct: 334 DIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPK 393
Query: 120 KKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKS 179
K Q K ++H EP PK+ PS+K
Sbjct: 394 GKKQE--------------KKEKHVEPAKSPKKEHSV------------------PSDKQ 421
Query: 180 TEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAA 239
+ KT+ E + ++ PG KKE+K+ T V E + +K SGK+ +
Sbjct: 422 VKAKTE------RAKEEIGAVSIKKAVPG--KKEEKT-TKTVEQEIRKEK-SGKT--SSI 469
Query: 240 LDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGIT 299
L D + + G EE + PE E++ K + PK +L KKE
Sbjct: 470 LKDK-EPIKGKEEKVPASLKEKEPETKKD------EKMSKAGKEVKPKPPQLQGKKEEKP 522
Query: 300 GPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQE 359
P + + D T + K E+ +VLK A T+ A P+
Sbjct: 523 EPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEE----KVLKQVKAVTIEKTAKPKP 578
Query: 360 KKR-----------KVEKDTMSDQALEALSAS------LGTRQAEPELDLRSIKEVDEAK 402
K+ K +K + + ++ S + ++++ + D++ ++E +
Sbjct: 579 TKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKVST 638
Query: 403 AKE----------EKLEKCGEDDETIPSEYRLKPATD 429
KE EK + +D E +P+ + K T+
Sbjct: 639 RKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTE 675
Score = 43.9 bits (102), Expect = 6e-04
Identities = 65/307 (21%), Positives = 110/307 (35%), Gaps = 59/307 (19%)
Query: 507 TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 566
T KG + + + K E + + + KV K KE+ +EK+ EKE+
Sbjct: 128 TDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHK 187
Query: 567 EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 626
E+++ K+ KP +KEQ + + + ++ G K E K AA + V
Sbjct: 188 EKIEKKE-KPETKTLAKEQKKAKTAEKSEEKTKKEVKGG------KQEKVKQTAAKVKEV 240
Query: 627 SQTPASTTQAGAPPRDTSQSDKDLD---------------DALDKLSDSLGQRQPDPDEN 671
+TP+ + + + D D S ++ P +
Sbjct: 241 QKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQAS 300
Query: 672 KP------MEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK--SED 723
+P +E+K EK KAE K V TKK ED
Sbjct: 301 RPTPASPALEEKEGEKKKAE--------------------------KKVTSETKKKEKED 334
Query: 724 SKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTE 783
KK ++ + ID + +ET Q T K + AA + ++ K K A+ +
Sbjct: 335 IKKKSEKETAIDV---EKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQ 391
Query: 784 ETSKPKD 790
K ++
Sbjct: 392 PKGKKQE 398
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 70.1 bits (170), Expect = 8e-12
Identities = 151/713 (21%), Positives = 270/713 (37%), Gaps = 110/713 (15%)
Query: 28 SEKTSESPSKPGEKK-GSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNP 86
+ + S S + G K G D +KA G + + T G A + + G++S + +P
Sbjct: 692 ARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGT-DGILAGSQEHDPGQGSSSPEQAGSP 750
Query: 87 TETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEP 146
TE + + + + P KK K++ E+KS+ S G EH+ P
Sbjct: 751 TEGEGVSTWESFKRLVTPRKKS------KSKLEEKSED----------SIAGSGVEHSTP 794
Query: 147 KSLPKQASDTGS----NDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 202
+ P + S KK EQ P E + D ++ A
Sbjct: 795 DTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDA 854
Query: 203 ISGKPGDKKKEKKSL-TPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYT 261
+ + + ++ +KS P ++ K +S + + D EE + ++
Sbjct: 855 VEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWI 914
Query: 262 GPEVSDPM------SSTYIEELGKREVTI---PPKYRELLAKKEGITGPPADSSKPIGPD 312
V++P+ ++ EE+ +REV PP E L + G S + P
Sbjct: 915 SASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTP- 973
Query: 313 DAIDALSSDFTCGSPTAAGKKTE---KEESTEVLKA-----QSAGTVRSAAPPQEKKRKV 364
+A+++ T G P A + TE EE+TE++ A S T A P QE + V
Sbjct: 974 ---EAVTAAETAG-PLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGV 1029
Query: 365 ----EKDTMSDQALEALSASLGTRQ-----AEPELDLRSIKEVDEAKAKEEKLEKCGEDD 415
E++ + + L+A++ + PE L+ ++ EA+ EE+ E G
Sbjct: 1030 PDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRA-EAERPEEQAEASG--- 1085
Query: 416 ETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT 475
LK TD K + E K +P ++ +++ + + E EK + TE
Sbjct: 1086 --------LKKETDVVLK--VDAQEAKTEPFTQGKVVGQTT-----PESFEKAPQVTESI 1130
Query: 476 EESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPED-- 533
E SE V ++ + ++ +P D+VE DS D
Sbjct: 1131 ES---------SELVTTCQAETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFD 1181
Query: 534 --GKPVMDKVKEKAKEED----REKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ-- 585
G D++ E +E + + G + E +P +E + +E+KEQ
Sbjct: 1182 APGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQ---KERPPAPSSFVFQEETKEQSK 1238
Query: 586 ----LPPMSEDFLLDALS--EDFSGPQNASSLKFEDAK-------LAAAISEVVSQTPAS 632
L ++ ++ +S G Q A E K L +I ++ +
Sbjct: 1239 MEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREK 1298
Query: 633 TTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 685
T+ T +++ DDAL+ S + + P P E + + +EK +AE
Sbjct: 1299 VTEVALKGEGTEEAECKKDDALELQSHA--KSPPSPVEREMVVQVEREKTEAE 1349
Score = 55.8 bits (133), Expect = 1e-07
Identities = 164/845 (19%), Positives = 319/845 (37%), Gaps = 138/845 (16%)
Query: 3 QPGQKPAASPR-PRRAAAARRTHEHVSE--KTSESPSKPGEKKGSDEKKAASLGSSQSSR 59
Q G+ A+SP P + V + + E + GEKK AS + +
Sbjct: 561 QKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPK 620
Query: 60 TYAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPE 119
+ + K KS++++ TE+ A + ++M+G K + K+ V T
Sbjct: 621 KRVRRPSESDKEDELDKV--KSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVS 678
Query: 120 KKS-----QSTKLSVVHEKKSQEGKPK----EHTEPKSLPKQASDTGSNDAHNKKAVSRS 170
++ S K + +EG PK +H + K +TG++ ++ S
Sbjct: 679 WEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKD-KETGTDG-----ILAGS 732
Query: 171 AEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKP 230
E P + S+ P+ Q GE V+ + +KK K L E K +
Sbjct: 733 QEHDPGQGSSSPE---QAGSPTEGEGVSTWESFKRLVTPRKKSKSKL------EEKSEDS 783
Query: 231 SGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE 290
SG++ + D T G E S +I G+R+ K +
Sbjct: 784 IAGSGVEHSTPD----------------TEPGKEESWVSIKKFIP--GRRKKRPDGKQEQ 825
Query: 291 LLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGT 350
+ G TG D SD P + E+E+ ++AQ A
Sbjct: 826 APVEDAGPTGANED--------------DSDVPAVVPLSEYDAVEREK----MEAQQA-- 865
Query: 351 VRSAAPPQEKKRKVEKDTMSDQALEALSASL--GTRQAEPELDLRSIKEVDEAKAKEEKL 408
+SA P++K +S+ + ++A++ GTR A ++ RS + + + E L
Sbjct: 866 QKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTR-AATIIEERSPSWI--SASVTEPL 922
Query: 409 EKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKP 468
E+ + + E + ++ P + EP + + ++ E +E + +
Sbjct: 923 EQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSE-AELTPEAVTAAET 981
Query: 469 SKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPAT----LKGTVPD---------D 515
+ P E ++A+A +E V S + E AT ++G VPD +
Sbjct: 982 AGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQE 1041
Query: 516 AVEALADSLGKKE-----ADPEDGKPVMDKVKEKAKEEDREKLGEKEET-IPPDYRLEEV 569
++A+A+ + ++ PED + + + + EE E G K+ET + +E
Sbjct: 1042 VLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEA 1101
Query: 570 KDK---DGKPL--LPKESKEQLPPMSE-----DFLLDALSEDFSGPQNASSLKFEDAKLA 619
K + GK + ES E+ P ++E + + +E +G ++ + +
Sbjct: 1102 KTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPD 1161
Query: 620 AAISEVVSQTPASTTQAGAPPRDTSQSDK--DLDDALDKLSDSLG-----------QRQP 666
+ + S+T ST A T+Q D+ ++ + + S + + +P
Sbjct: 1162 SVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERP 1221
Query: 667 DPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKK 726
+ +++ KE++K E D L D + E +L T+ ++++ +
Sbjct: 1222 PAPSSFVFQEETKEQSKME--DTLEHTDKEVSVETVSILS----------KTEGTQEADQ 1269
Query: 727 PADDQDP----IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTT 782
AD++ + L G +D T +++K + A + + KD A
Sbjct: 1270 YADEKTKDVPFFEGLEGSID-------TGITVSREKVTEVALKGEGTEEAECKKDDALEL 1322
Query: 783 EETSK 787
+ +K
Sbjct: 1323 QSHAK 1327
Score = 50.4 bits (119), Expect = 6e-06
Identities = 147/801 (18%), Positives = 298/801 (37%), Gaps = 126/801 (15%)
Query: 64 GTASATKVSASSGATSKSSSMNP------TETKAIPVSQQMEG--PHLPNKKKHKKQAVK 115
G T+ SA+ T S+++ T +A PV Q++EG P + +++ ++ ++
Sbjct: 986 GAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPV-QEVEGGVPDIEEQERRTQEVLQ 1044
Query: 116 TEPEKKSQSTKLS--------VVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAV 167
EK + ++L + ++++ +P+E E L K+ DA K
Sbjct: 1045 AVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTE 1104
Query: 168 SRSAEQQPSEKSTEPKTK-PQDMISAGGESVAGITAISGKPGDKKKE---KKSLTP---A 220
+ + + + E K PQ S + G K +E ++++ P
Sbjct: 1105 PFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSVE 1164
Query: 221 VPVESKPDKPSGKSGMDAA----LDDLIDTLGGPEETEEENTTYTGPEVSD--------- 267
P +S+ D + + DA D++++ EE E + T +G ++
Sbjct: 1165 TPTDSETDGSTPVADFDAPGTTQKDEIVEI---HEENEVASGTQSGGTEAEAVPAQKERP 1221
Query: 268 PMSSTYI-----EELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPDDAI 315
P S+++ +E K E T+ +E +L+K EG + +
Sbjct: 1222 PAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFF 1281
Query: 316 DALSSDFTCGSPTAAGKKTE---KEESTEVLKAQSAGTVR----SAAPP----------- 357
+ L G + K TE K E TE + + + + +PP
Sbjct: 1282 EGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREMVVQV 1341
Query: 358 QEKKRKVEKDTMSDQALEALSASLGTRQAEPEL----DLRSIKEVDEAKAKEEKLEKCGE 413
+ +K + E ++++ LE +A + + +L ++ I E + E C
Sbjct: 1342 EREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLG 1401
Query: 414 DDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 473
+E + ++ +++ + + L E+ K E+ I E E + + + +
Sbjct: 1402 QEEAVCTKIQVQSS---EASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEKSS 1458
Query: 474 KTEESKAAAPAPVSEAVCRTSMCSIQSAPP-EPATLKGTVPDDAVEALADSLGKKEADPE 532
+ E AA P +AV C +S P AT K + D SL K ++D
Sbjct: 1459 EKNEDFAAHPG--EDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSL-KWKSDEV 1515
Query: 533 DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 592
D + +VK ED E P+ + E++ K K + ++
Sbjct: 1516 DEQVACQEVKVSVAIEDLE----------PENGILELETKSSK-------------LVQN 1552
Query: 593 FLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQA-GAPPRDTSQSDKDLD 651
+ A+ + + A+ + + + A + + SQ T+ G P+ ++Q + +
Sbjct: 1553 IIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPIT 1612
Query: 652 DALDKLSDSLGQRQPDPDENKPMED------------------KVKEKAKAEHRDKLGER 693
A ++ S+S Q D +K M + +++E + G
Sbjct: 1613 SAKEE-SESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAG 1671
Query: 694 DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQN 753
++P + H L +K + P K ++ DD + ++ D D+ T+ S +
Sbjct: 1672 TKSVPEDDGHALLAERIEKSLVEP--KEDEKGDDVDDPENQNSALADTDASGGLTKESPD 1729
Query: 754 TAKDKCKKAASSSKAPKNGGK 774
T K K+ + + GK
Sbjct: 1730 TNGPKQKEKEDAQEVELQEGK 1750
Score = 42.7 bits (99), Expect = 0.001
Identities = 152/747 (20%), Positives = 254/747 (34%), Gaps = 104/747 (13%)
Query: 111 KQAVKTEPEKKSQSTKLSVVHEKKSQEGKPK----EHTEPKSLPKQASDTGSNDAHNKKA 166
K VK + +K + +L V K EG+ +H +P A + S ++ K++
Sbjct: 182 KFTVKKDKTEKPDTVQLLTV---KKDEGEGAAGAGDHKDPSL---GAGEAASKESEPKQS 235
Query: 167 VSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESK 226
+ E E+S + P + G++V + +K+ K + +P PV S+
Sbjct: 236 TEKPEETLKREQSHAEISPPAE----SGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSE 291
Query: 227 PDKPSGKSGMDAALDDLIDT-LGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 285
K T P+E E E + + + + + EE GK EV
Sbjct: 292 TGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDT---EEDGKAEVAS- 347
Query: 286 PKYRELLAKKEGITGPPADSS---KPIGPDDAIDALSSDFTCGS---------PTAAGKK 333
+L A ++ PA+S+ + + ++ S + GS P A
Sbjct: 348 ---EKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVF 404
Query: 334 TEKEE--STEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELD 391
EK E EV+ TV +E+K +VE+ S A E + ++AEP +
Sbjct: 405 DEKIEVHQEEVVAEVHVSTVEERT--EEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKE 462
Query: 392 LRSIKEV--------------DEAKAKEEKLEKCGEDDETIPSEYR-------LKPATDK 430
L +KE + K + E + E + S+ R LK
Sbjct: 463 LVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTS 522
Query: 431 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 490
G L ++K K E E ++ + P E+ ES A++P E
Sbjct: 523 TGLKKLSGKKQKGKRGGGDEESGEHTQ-----VPADSPDSQEEQKGESSASSPEEPEEIT 577
Query: 491 C-RTSMCSIQ--SAPPEPATLKGTVPDDAVEALADSLGKKEADPE---------DGKPVM 538
C + +Q E AT G + V A KK P+ D + +
Sbjct: 578 CLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASF--KKMVTPKKRVRRPSESDKEDEL 635
Query: 539 DKVK--------EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL----PKESKEQL 586
DKVK A E E G EE P + + + + L+ K+ +
Sbjct: 636 DKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRG 695
Query: 587 PPMSEDFLLDALSEDFSGPQNASSLK--FEDAKLAAAISEVVSQTPASTTQAGAPPR--- 641
E+ A+ D A K D LA + Q +S QAG+P
Sbjct: 696 SSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEG 755
Query: 642 -DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPE 700
T +S K L K L ++ D +E + + + + IP
Sbjct: 756 VSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSIK-KFIPGR 814
Query: 701 YRHLLDDNGQDKPVKP--PTKKSEDSKK-----PADDQDPIDALSGDLDSCPSTTETSQN 753
+ D + PV+ PT +ED P + D ++ + + E +
Sbjct: 815 RKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQ 874
Query: 754 TAKDKCKKAASSSKAPKNGGKAKDSAK 780
A + K S S+ D +
Sbjct: 875 KAATEVSKELSESQVHMMAAAVADGTR 901
Score = 32.7 bits (73), Expect = 1.3
Identities = 57/227 (25%), Positives = 90/227 (39%), Gaps = 35/227 (15%)
Query: 161 AHNKKAVSRSAEQQPSEKSTEPKTKPQD---MISAGGESVAGITAISGKPGDKKK---EK 214
AH KA S+ A Q+ ++ EP+ QD + SA ES + TA+ D K E
Sbjct: 1580 AHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESES--TAVGQAHSDISKDMSEA 1637
Query: 215 KSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYI 274
T V VE G + D L++++ L EE T + + + I
Sbjct: 1638 SEKTMTVEVE-------GSTVNDQQLEEVV--LPSEEEGGGAGTKSVPEDDGHALLAERI 1688
Query: 275 EELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAG-KK 333
E + + PK E K P + + + DA L+ + SP G K+
Sbjct: 1689 E-----KSLVEPKEDE----KGDDVDDPENQNSALADTDASGGLTKE----SPDTNGPKQ 1735
Query: 334 TEKEESTEVL----KAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA 376
EKE++ EV K S QE+ +K E+++ + E+
Sbjct: 1736 KEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES 1782
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 70.1 bits (170), Expect = 8e-12
Identities = 151/713 (21%), Positives = 270/713 (37%), Gaps = 110/713 (15%)
Query: 28 SEKTSESPSKPGEKK-GSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNP 86
+ + S S + G K G D +KA G + + T G A + + G++S + +P
Sbjct: 594 ARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGT-DGILAGSQEHDPGQGSSSPEQAGSP 652
Query: 87 TETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEP 146
TE + + + + P KK K++ E+KS+ S G EH+ P
Sbjct: 653 TEGEGVSTWESFKRLVTPRKKS------KSKLEEKSED----------SIAGSGVEHSTP 696
Query: 147 KSLPKQASDTGS----NDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITA 202
+ P + S KK EQ P E + D ++ A
Sbjct: 697 DTEPGKEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDA 756
Query: 203 ISGKPGDKKKEKKSL-TPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYT 261
+ + + ++ +KS P ++ K +S + + D EE + ++
Sbjct: 757 VEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWI 816
Query: 262 GPEVSDPM------SSTYIEELGKREVTI---PPKYRELLAKKEGITGPPADSSKPIGPD 312
V++P+ ++ EE+ +REV PP E L + G S + P
Sbjct: 817 SASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTP- 875
Query: 313 DAIDALSSDFTCGSPTAAGKKTE---KEESTEVLKA-----QSAGTVRSAAPPQEKKRKV 364
+A+++ T G P A + TE EE+TE++ A S T A P QE + V
Sbjct: 876 ---EAVTAAETAG-PLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGV 931
Query: 365 ----EKDTMSDQALEALSASLGTRQ-----AEPELDLRSIKEVDEAKAKEEKLEKCGEDD 415
E++ + + L+A++ + PE L+ ++ EA+ EE+ E G
Sbjct: 932 PDIEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRA-EAERPEEQAEASG--- 987
Query: 416 ETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKT 475
LK TD K + E K +P ++ +++ + + E EK + TE
Sbjct: 988 --------LKKETDVVLK--VDAQEAKTEPFTQGKVVGQTT-----PESFEKAPQVTESI 1032
Query: 476 EESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPED-- 533
E SE V ++ + ++ +P D+VE DS D
Sbjct: 1033 ES---------SELVTTCQAETLAGVKSQEMVMEQAIPPDSVETPTDSETDGSTPVADFD 1083
Query: 534 --GKPVMDKVKEKAKEED----REKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQ-- 585
G D++ E +E + + G + E +P +E + +E+KEQ
Sbjct: 1084 APGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQ---KERPPAPSSFVFQEETKEQSK 1140
Query: 586 ----LPPMSEDFLLDALS--EDFSGPQNASSLKFEDAK-------LAAAISEVVSQTPAS 632
L ++ ++ +S G Q A E K L +I ++ +
Sbjct: 1141 MEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFFEGLEGSIDTGITVSREK 1200
Query: 633 TTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 685
T+ T +++ DDAL+ S + + P P E + + +EK +AE
Sbjct: 1201 VTEVALKGEGTEEAECKKDDALELQSHA--KSPPSPVEREMVVQVEREKTEAE 1251
Score = 55.8 bits (133), Expect = 1e-07
Identities = 164/845 (19%), Positives = 319/845 (37%), Gaps = 138/845 (16%)
Query: 3 QPGQKPAASPR-PRRAAAARRTHEHVSE--KTSESPSKPGEKKGSDEKKAASLGSSQSSR 59
Q G+ A+SP P + V + + E + GEKK AS + +
Sbjct: 463 QKGESSASSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPK 522
Query: 60 TYAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPE 119
+ + K KS++++ TE+ A + ++M+G K + K+ V T
Sbjct: 523 KRVRRPSESDKEDELDKV--KSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVS 580
Query: 120 KKS-----QSTKLSVVHEKKSQEGKPK----EHTEPKSLPKQASDTGSNDAHNKKAVSRS 170
++ S K + +EG PK +H + K +TG++ ++ S
Sbjct: 581 WEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKD-KETGTDG-----ILAGS 634
Query: 171 AEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKP 230
E P + S+ P+ Q GE V+ + +KK K L E K +
Sbjct: 635 QEHDPGQGSSSPE---QAGSPTEGEGVSTWESFKRLVTPRKKSKSKL------EEKSEDS 685
Query: 231 SGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE 290
SG++ + D T G E S +I G+R+ K +
Sbjct: 686 IAGSGVEHSTPD----------------TEPGKEESWVSIKKFIP--GRRKKRPDGKQEQ 727
Query: 291 LLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGT 350
+ G TG D SD P + E+E+ ++AQ A
Sbjct: 728 APVEDAGPTGANED--------------DSDVPAVVPLSEYDAVEREK----MEAQQA-- 767
Query: 351 VRSAAPPQEKKRKVEKDTMSDQALEALSASL--GTRQAEPELDLRSIKEVDEAKAKEEKL 408
+SA P++K +S+ + ++A++ GTR A ++ RS + + + E L
Sbjct: 768 QKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTR-AATIIEERSPSWI--SASVTEPL 824
Query: 409 EKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKP 468
E+ + + E + ++ P + EP + + ++ E +E + +
Sbjct: 825 EQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSE-AELTPEAVTAAET 883
Query: 469 SKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPAT----LKGTVPD---------D 515
+ P E ++A+A +E V S + E AT ++G VPD +
Sbjct: 884 AGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQE 943
Query: 516 AVEALADSLGKKE-----ADPEDGKPVMDKVKEKAKEEDREKLGEKEET-IPPDYRLEEV 569
++A+A+ + ++ PED + + + + EE E G K+ET + +E
Sbjct: 944 VLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEA 1003
Query: 570 KDK---DGKPL--LPKESKEQLPPMSE-----DFLLDALSEDFSGPQNASSLKFEDAKLA 619
K + GK + ES E+ P ++E + + +E +G ++ + +
Sbjct: 1004 KTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPD 1063
Query: 620 AAISEVVSQTPASTTQAGAPPRDTSQSDK--DLDDALDKLSDSLG-----------QRQP 666
+ + S+T ST A T+Q D+ ++ + + S + + +P
Sbjct: 1064 SVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERP 1123
Query: 667 DPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKK 726
+ +++ KE++K E D L D + E +L T+ ++++ +
Sbjct: 1124 PAPSSFVFQEETKEQSKME--DTLEHTDKEVSVETVSILS----------KTEGTQEADQ 1171
Query: 727 PADDQDP----IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTT 782
AD++ + L G +D T +++K + A + + KD A
Sbjct: 1172 YADEKTKDVPFFEGLEGSID-------TGITVSREKVTEVALKGEGTEEAECKKDDALEL 1224
Query: 783 EETSK 787
+ +K
Sbjct: 1225 QSHAK 1229
Score = 50.4 bits (119), Expect = 6e-06
Identities = 147/801 (18%), Positives = 298/801 (37%), Gaps = 126/801 (15%)
Query: 64 GTASATKVSASSGATSKSSSMNP------TETKAIPVSQQMEG--PHLPNKKKHKKQAVK 115
G T+ SA+ T S+++ T +A PV Q++EG P + +++ ++ ++
Sbjct: 888 GAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPV-QEVEGGVPDIEEQERRTQEVLQ 946
Query: 116 TEPEKKSQSTKLS--------VVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAV 167
EK + ++L + ++++ +P+E E L K+ DA K
Sbjct: 947 AVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTE 1006
Query: 168 SRSAEQQPSEKSTEPKTK-PQDMISAGGESVAGITAISGKPGDKKKE---KKSLTP---A 220
+ + + + E K PQ S + G K +E ++++ P
Sbjct: 1007 PFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSVE 1066
Query: 221 VPVESKPDKPSGKSGMDAA----LDDLIDTLGGPEETEEENTTYTGPEVSD--------- 267
P +S+ D + + DA D++++ EE E + T +G ++
Sbjct: 1067 TPTDSETDGSTPVADFDAPGTTQKDEIVEI---HEENEVASGTQSGGTEAEAVPAQKERP 1123
Query: 268 PMSSTYI-----EELGKREVTIPPKYRE-------LLAKKEGITGPPADSSKPIGPDDAI 315
P S+++ +E K E T+ +E +L+K EG + +
Sbjct: 1124 PAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEGTQEADQYADEKTKDVPFF 1183
Query: 316 DALSSDFTCGSPTAAGKKTE---KEESTEVLKAQSAGTVR----SAAPP----------- 357
+ L G + K TE K E TE + + + + +PP
Sbjct: 1184 EGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVEREMVVQV 1243
Query: 358 QEKKRKVEKDTMSDQALEALSASLGTRQAEPEL----DLRSIKEVDEAKAKEEKLEKCGE 413
+ +K + E ++++ LE +A + + +L ++ I E + E C
Sbjct: 1244 EREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEGSPPPCLG 1303
Query: 414 DDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 473
+E + ++ +++ + + L E+ K E+ I E E + + + +
Sbjct: 1304 QEEAVCTKIQVQSS---EASFTLTAAAEEEKVLGETANILETGETLEPAGAHLVLEEKSS 1360
Query: 474 KTEESKAAAPAPVSEAVCRTSMCSIQSAPP-EPATLKGTVPDDAVEALADSLGKKEADPE 532
+ E AA P +AV C +S P AT K + D SL K ++D
Sbjct: 1361 EKNEDFAAHPG--EDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEKTTSL-KWKSDEV 1417
Query: 533 DGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 592
D + +VK ED E P+ + E++ K K + ++
Sbjct: 1418 DEQVACQEVKVSVAIEDLE----------PENGILELETKSSK-------------LVQN 1454
Query: 593 FLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQA-GAPPRDTSQSDKDLD 651
+ A+ + + A+ + + + A + + SQ T+ G P+ ++Q + +
Sbjct: 1455 IIQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPIT 1514
Query: 652 DALDKLSDSLGQRQPDPDENKPMED------------------KVKEKAKAEHRDKLGER 693
A ++ S+S Q D +K M + +++E + G
Sbjct: 1515 SAKEE-SESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAG 1573
Query: 694 DDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQN 753
++P + H L +K + P K ++ DD + ++ D D+ T+ S +
Sbjct: 1574 TKSVPEDDGHALLAERIEKSLVEP--KEDEKGDDVDDPENQNSALADTDASGGLTKESPD 1631
Query: 754 TAKDKCKKAASSSKAPKNGGK 774
T K K+ + + GK
Sbjct: 1632 TNGPKQKEKEDAQEVELQEGK 1652
Score = 42.7 bits (99), Expect = 0.001
Identities = 152/747 (20%), Positives = 254/747 (34%), Gaps = 104/747 (13%)
Query: 111 KQAVKTEPEKKSQSTKLSVVHEKKSQEGKPK----EHTEPKSLPKQASDTGSNDAHNKKA 166
K VK + +K + +L V K EG+ +H +P A + S ++ K++
Sbjct: 84 KFTVKKDKTEKPDTVQLLTV---KKDEGEGAAGAGDHKDPSL---GAGEAASKESEPKQS 137
Query: 167 VSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESK 226
+ E E+S + P + G++V + +K+ K + +P PV S+
Sbjct: 138 TEKPEETLKREQSHAEISPPAE----SGQAVEECKEEGEEKQEKEPSKSAESPTSPVTSE 193
Query: 227 PDKPSGKSGMDAALDDLIDT-LGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIP 285
K T P+E E E + + + + + EE GK EV
Sbjct: 194 TGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDT---EEDGKAEVAS- 249
Query: 286 PKYRELLAKKEGITGPPADSS---KPIGPDDAIDALSSDFTCGS---------PTAAGKK 333
+L A ++ PA+S+ + + ++ S + GS P A
Sbjct: 250 ---EKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVF 306
Query: 334 TEKEE--STEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELD 391
EK E EV+ TV +E+K +VE+ S A E + ++AEP +
Sbjct: 307 DEKIEVHQEEVVAEVHVSTVEERT--EEQKTEVEETAGSVPAEELVEMDAEPQEAEPAKE 364
Query: 392 LRSIKEV--------------DEAKAKEEKLEKCGEDDETIPSEYR-------LKPATDK 430
L +KE + K + E + E + S+ R LK
Sbjct: 365 LVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTS 424
Query: 431 DGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAV 490
G L ++K K E E ++ + P E+ ES A++P E
Sbjct: 425 TGLKKLSGKKQKGKRGGGDEESGEHTQ-----VPADSPDSQEEQKGESSASSPEEPEEIT 479
Query: 491 C-RTSMCSIQ--SAPPEPATLKGTVPDDAVEALADSLGKKEADPE---------DGKPVM 538
C + +Q E AT G + V A KK P+ D + +
Sbjct: 480 CLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASF--KKMVTPKKRVRRPSESDKEDEL 537
Query: 539 DKVK--------EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL----PKESKEQL 586
DKVK A E E G EE P + + + + L+ K+ +
Sbjct: 538 DKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRG 597
Query: 587 PPMSEDFLLDALSEDFSGPQNASSLK--FEDAKLAAAISEVVSQTPASTTQAGAPPR--- 641
E+ A+ D A K D LA + Q +S QAG+P
Sbjct: 598 SSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTEGEG 657
Query: 642 -DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPE 700
T +S K L K L ++ D +E + + + + IP
Sbjct: 658 VSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEESWVSIK-KFIPGR 716
Query: 701 YRHLLDDNGQDKPVKP--PTKKSEDSKK-----PADDQDPIDALSGDLDSCPSTTETSQN 753
+ D + PV+ PT +ED P + D ++ + + E +
Sbjct: 717 RKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVEREKMEAQQAQKSAEQPEQ 776
Query: 754 TAKDKCKKAASSSKAPKNGGKAKDSAK 780
A + K S S+ D +
Sbjct: 777 KAATEVSKELSESQVHMMAAAVADGTR 803
Score = 32.7 bits (73), Expect = 1.3
Identities = 57/227 (25%), Positives = 90/227 (39%), Gaps = 35/227 (15%)
Query: 161 AHNKKAVSRSAEQQPSEKSTEPKTKPQD---MISAGGESVAGITAISGKPGDKKK---EK 214
AH KA S+ A Q+ ++ EP+ QD + SA ES + TA+ D K E
Sbjct: 1482 AHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESES--TAVGQAHSDISKDMSEA 1539
Query: 215 KSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYI 274
T V VE G + D L++++ L EE T + + + I
Sbjct: 1540 SEKTMTVEVE-------GSTVNDQQLEEVV--LPSEEEGGGAGTKSVPEDDGHALLAERI 1590
Query: 275 EELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAG-KK 333
E + + PK E K P + + + DA L+ + SP G K+
Sbjct: 1591 E-----KSLVEPKEDE----KGDDVDDPENQNSALADTDASGGLTKE----SPDTNGPKQ 1637
Query: 334 TEKEESTEVL----KAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA 376
EKE++ EV K S QE+ +K E+++ + E+
Sbjct: 1638 KEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES 1684
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 67.8 bits (164), Expect = 4e-11
Identities = 192/858 (22%), Positives = 305/858 (35%), Gaps = 141/858 (16%)
Query: 10 ASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSR-------TYA 62
+SP+P+ A T VS K+S P + KK + K+ S T
Sbjct: 655 SSPQPKLKTAPVTTTSAVS-KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 63 GGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKS 122
G ++ K + + SK + P + ++P S+Q + P +K K K VK + S
Sbjct: 714 GSPSAKAKQPPEADSLSKPA---PPKEPSVP-SEQDKAPVADDKPKQPKM-VKPTTDLVS 768
Query: 123 QSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEP 182
S S + K + E K+ P +D SA+ S T
Sbjct: 769 SS---SATTKPDIPSSKVQSQAEEKTTPPLKTD--------------SAKPSQSFPPTGE 811
Query: 183 KTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDD 242
K P D S A + I PG E K PV+ K + ++ M D
Sbjct: 812 KVSPFD--SKAIPRPASDSKIISHPGPSS-ESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Query: 243 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPP 302
G P T G V P S +E +R IT P
Sbjct: 869 KPMPKGSPTPPGPRPTA--GQTVPTPQQSPKPQEQSRR----------FSLNLGSITDAP 916
Query: 303 ADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKR 362
S+P P + + F G + S + A G + P K+
Sbjct: 917 --KSQPTTPQETVTGKLFGF--------GASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 363 KVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE-EKLEKCGEDDETIP-S 420
Q + T QA P +SI E KA EKLE E T+ +
Sbjct: 967 A----PAPSQPPTSQGPPKSTGQAPPA-PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 421 EYRLKPATDKDGKPLLPEP---------EEKPKPRSESELI-DELS------EDFDR-SE 463
E KP KD K L EP E+ PKP S L EL+ +F+ +E
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
Query: 464 CKEKPS-----KPT-EKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGT---VPD 514
CK + PT TE + ++ + I+ PP P+ K + VP
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141
Query: 515 D------AVEALADSLGKKEAD--PEDGKPVMDKVKEKAK-------------------E 547
+ AV + K+E + E K +++KVKE E
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201
Query: 548 EDREKLGEKEETIPPDYRL----EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFS 603
+D+ ++++ +P + +L E+++ ++ KPLL +E+ P + LL
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLL----EEKKPTPEDKKLLPEAKTSAP 1257
Query: 604 GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD-----TSQSDKDLDDALDKLS 658
Q LK +++ A ++ + T Q G P+ S + + L DK +
Sbjct: 1258 EEQKHDLLK---SQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTT 1314
Query: 659 DSLGQRQPDPDENKPMEDKVKE-KAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPP 717
++ ++ P KP D+V+ K K E D + + P+ L D G
Sbjct: 1315 KTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372
Query: 718 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK-----KAASSSKAPKNG 772
+ S P D++D + L D S S+ + + AK + +A +S+ A +
Sbjct: 1373 SLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS 1432
Query: 773 GKAKDSAKTTEETSKPKD 790
K + + E +PKD
Sbjct: 1433 EKKTQPHEVSPE--QPKD 1448
Score = 54.3 bits (129), Expect = 4e-07
Identities = 104/500 (20%), Positives = 191/500 (38%), Gaps = 70/500 (14%)
Query: 37 KPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAI---- 92
+PG++K E + SSQ ++ G + + S + + S+ PT+ K I
Sbjct: 1333 EPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGL 1392
Query: 93 --PVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQ-----EGKPKEHTE 145
Q P P+ + V + E ++ ST EKK+Q +PK+ +
Sbjct: 1393 KKDSFSQESSPSSPSDLAKLESTVLSILEAQA-STLADEKSEKKTQPHEVSPEQPKDQEK 1451
Query: 146 PKSLPKQASDTGSNDAHNKKAVSR-------SAEQQPSEKSTEPKTKPQDMISAGGE--- 195
+SL + T S + + R S + PS K + K++ D I+ E
Sbjct: 1452 TQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYD 1511
Query: 196 SVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGK-SGMDAALDDLIDTLGGPEETE 254
SV + P ++K + S+ + E K + G D +I+ + +
Sbjct: 1512 SVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASG 1571
Query: 255 EENTTYTGPEVSDPMSSTYI----EELGKREVTIPPKYRELLAKKEGITGPPADSSKPIG 310
E+ + ++ + SST E GK ++T K+R L K T D+ +
Sbjct: 1572 SEDDEFIRNQLKEISSSTESQKKEETKGKGKIT-AGKHRRLTRKSS--TSIDEDAGRRHS 1628
Query: 311 PDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMS 370
D D + SP ++T+ +ES E++ G R + +E ++
Sbjct: 1629 WHDEDDEAFDE----SPELKYRETKSQESEELVVTGGGGLRRF--------KTIELNSTI 1676
Query: 371 DQALEALSASLGTR---QAEPELDLRSIKEVDEAKAKEE-----------------KLEK 410
A S+ T EPEL++ S+ + E +++ E +
Sbjct: 1677 ADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSS 1736
Query: 411 CGEDDETIPSEYR-----LKPATDKDGKPLLP---EPEEKPKPRSESELIDELSEDFDRS 462
ED ++ PS + + A + PLLP + E+ + R E EL+ E + +
Sbjct: 1737 LDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIE 1796
Query: 463 ECKEKPSKPTEKTEESKAAA 482
+ + K S K ++ + A
Sbjct: 1797 QQQRKSSSKKSKKDKDELRA 1816
Score = 50.4 bits (119), Expect = 6e-06
Identities = 155/777 (19%), Positives = 261/777 (33%), Gaps = 95/777 (12%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ P + P P P + A + HE K+ P+KP + K A +
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHE----KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 61 YAGGTASA-------TKVSASSGATSKSSSMNP-TETKAIPVSQQMEGPHLPNKKKHKKQ 112
GT K A + K SS P + A P P K Q
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413
Query: 113 AVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHN--------- 163
V T P+ +Q L + P + P +P Q + G A
Sbjct: 414 QVGT-PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 164 ----------KKAVSRSAEQQPSEK--------STEPKTKPQDMISAGGESVAGITAISG 205
+ ++ QQP ST+P + + S
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 206 KPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEV 265
+PG K + +PA P + KP ++G L + ++ + P+
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP-----PTVSPSAKQPPSQGLPKT 587
Query: 266 SDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSS--DFT 323
P+ +T + + +P K + T S P+ + +
Sbjct: 588 ICPLCNT-----TELLLHVPEKANFNTCTECQTT---VCSLCGFNPNPHLTEVKEWLCLN 639
Query: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAA----PPQEKKRKVEKDTMSDQALEALSA 379
C A G S+ K ++A ++A PQ ++ +KD Q LS
Sbjct: 640 CQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ---DLSK 696
Query: 380 SLGTRQAEPELDLRSIKEVDEAKAKE----EKLEKCGEDDE-TIPSEYRLKP-ATDKDGK 433
+ ++ P + ++ AKAK+ + L K E ++PSE P A DK +
Sbjct: 697 APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 434 PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 493
P + +P S + ++ +S+ +EK + P + + + P E V
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 494 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 553
A P PA+ + ++S G+K+ DP K K + K + K
Sbjct: 817 D----SKAIPRPASDSKIISHPGPS--SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
Query: 554 GEKEETIPPDYRLEEVKDKDGKPLLPK-ESKEQLPPMSEDFLLDALSEDFSGPQNASSLK 612
K PP R + PK + + + ++ + DA + PQ + K
Sbjct: 871 MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 613 F--EDAKLAAAISEVVSQT----PASTTQAGAPPRDT-SQSDKDLDDALDKLSDSLGQRQ 665
A + + S ++S P S + GAP + + S K S GQ
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK---STGQAP 987
Query: 666 PDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSE 722
P P ++ P VK++ KA +KL + + P R + KP PP K S+
Sbjct: 988 PAPAKSIP----VKKETKAPAAEKLEPKAEQAPTVKR----TETEKKP--PPIKDSK 1034
Score = 49.3 bits (116), Expect = 1e-05
Identities = 154/740 (20%), Positives = 268/740 (36%), Gaps = 152/740 (20%)
Query: 56 QSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVK 115
Q+ R +G K+ + S PTE+ SQ+ P K ++Q VK
Sbjct: 1110 QTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESS----SQKTAVPPQVKLVKKQEQEVK 1165
Query: 116 TEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQP 175
TE EK V+ EK KE + +P + + + SA Q+
Sbjct: 1166 TEAEK--------VILEKV------KETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211
Query: 176 SEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSG 235
E K P++ E + P DKK ++ T A P E K D KS
Sbjct: 1212 KPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSA-PEEQKHDLL--KSQ 1268
Query: 236 MDAALDDLIDTL-------GGPEETEEEN----TTYTGPEVSDPMSSTYIEE-----LGK 279
+ A + L + G +T+ E T + P+ D + T E+ K
Sbjct: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328
Query: 280 REVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDA-LSSDFTCGSPTAAGK-----K 333
+ P K + +KE + S +P P D SSD G ++ G+
Sbjct: 1329 PDQVEPGKEK---TEKEDDKSDTSSSQQPKSPQGLSDTGYSSD---GISSSLGEIPSLIP 1382
Query: 334 TEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLR 393
T++++ + LK S S + P + K+E +S LEA +++L ++E +
Sbjct: 1383 TDEKDILKGLKKDSFSQESSPSSPSDLA-KLESTVLS--ILEAQASTLADEKSEKKTQPH 1439
Query: 394 SI-----KEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 448
+ K+ ++ ++ E LE ++E S+ K KD + +P ++ + +
Sbjct: 1440 EVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDH---KEK 1496
Query: 449 SELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATL 508
SE +D+++ +P + EES + +PV + RTS+ S S
Sbjct: 1497 SEFVDDITTR----------REPYDSVEESSESENSPVPQRKRRTSVGSSSS-------- 1538
Query: 509 KGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEE 568
++ K+ED + GE+E+ I +E
Sbjct: 1539 ----------------------------------DEYKQEDSQGSGEEEDFIRKQI-IEM 1563
Query: 569 VKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE-DAKLAAAISEVVS 627
D+D ++F+ + L E S ++ + + K+ A ++
Sbjct: 1564 SADEDAS-----------GSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLT 1612
Query: 628 QTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHR 687
+ +++ A R S D+D D+A D+ S L R+ E+ E+ V R
Sbjct: 1613 RKSSTSIDEDAGRRH-SWHDED-DEAFDE-SPELKYRETKSQES---EELVVTGGGGLRR 1666
Query: 688 DKLGERDDTIPPEY--------RHLLDDNGQDKPVKPPTKKSEDSKK------------- 726
K E + TI +Y L D + ++ T ED +
Sbjct: 1667 FKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFT 1726
Query: 727 PADDQDPIDALSGDLDSCPS 746
P + +L D DS PS
Sbjct: 1727 PGTSPTSVSSLDEDSDSSPS 1746
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 67.8 bits (164), Expect = 4e-11
Identities = 192/858 (22%), Positives = 305/858 (35%), Gaps = 141/858 (16%)
Query: 10 ASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSR-------TYA 62
+SP+P+ A T VS K+S P + KK + K+ S T
Sbjct: 655 SSPQPKLKTAPVTTTSAVS-KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 63 GGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKS 122
G ++ K + + SK + P + ++P S+Q + P +K K K VK + S
Sbjct: 714 GSPSAKAKQPPEADSLSKPA---PPKEPSVP-SEQDKAPVADDKPKQPKM-VKPTTDLVS 768
Query: 123 QSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEP 182
S S + K + E K+ P +D SA+ S T
Sbjct: 769 SS---SATTKPDIPSSKVQSQAEEKTTPPLKTD--------------SAKPSQSFPPTGE 811
Query: 183 KTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDD 242
K P D S A + I PG E K PV+ K + ++ M D
Sbjct: 812 KVSPFD--SKAIPRPASDSKIISHPGPSS-ESKGQKQVDPVQKKEEPKKAQTKMSPKPDA 868
Query: 243 LIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPP 302
G P T G V P S +E +R IT P
Sbjct: 869 KPMPKGSPTPPGPRPTA--GQTVPTPQQSPKPQEQSRR----------FSLNLGSITDAP 916
Query: 303 ADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKR 362
S+P P + + F G + S + A G + P K+
Sbjct: 917 --KSQPTTPQETVTGKLFGF--------GASIFSQASNLISTAGQPGPHSQSGPGAPMKQ 966
Query: 363 KVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE-EKLEKCGEDDETIP-S 420
Q + T QA P +SI E KA EKLE E T+ +
Sbjct: 967 A----PAPSQPPTSQGPPKSTGQAPPA-PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 421 EYRLKPATDKDGKPLLPEP---------EEKPKPRSESELI-DELS------EDFDR-SE 463
E KP KD K L EP E+ PKP S L EL+ +F+ +E
Sbjct: 1022 ETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTE 1081
Query: 464 CKEKPS-----KPT-EKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGT---VPD 514
CK + PT TE + ++ + I+ PP P+ K + VP
Sbjct: 1082 CKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPT 1141
Query: 515 D------AVEALADSLGKKEAD--PEDGKPVMDKVKEKAK-------------------E 547
+ AV + K+E + E K +++KVKE E
Sbjct: 1142 ESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLE 1201
Query: 548 EDREKLGEKEETIPPDYRL----EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFS 603
+D+ ++++ +P + +L E+++ ++ KPLL +E+ P + LL
Sbjct: 1202 KDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLL----EEKKPTPEDKKLLPEAKTSAP 1257
Query: 604 GPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRD-----TSQSDKDLDDALDKLS 658
Q LK +++ A ++ + T Q G P+ S + + L DK +
Sbjct: 1258 EEQKHDLLK---SQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTT 1314
Query: 659 DSLGQRQPDPDENKPMEDKVKE-KAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPP 717
++ ++ P KP D+V+ K K E D + + P+ L D G
Sbjct: 1315 KTIKEQPQPPCTAKP--DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISS 1372
Query: 718 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK-----KAASSSKAPKNG 772
+ S P D++D + L D S S+ + + AK + +A +S+ A +
Sbjct: 1373 SLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS 1432
Query: 773 GKAKDSAKTTEETSKPKD 790
K + + E +PKD
Sbjct: 1433 EKKTQPHEVSPE--QPKD 1448
Score = 54.3 bits (129), Expect = 4e-07
Identities = 104/500 (20%), Positives = 191/500 (38%), Gaps = 70/500 (14%)
Query: 37 KPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAI---- 92
+PG++K E + SSQ ++ G + + S + + S+ PT+ K I
Sbjct: 1333 EPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGL 1392
Query: 93 --PVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQ-----EGKPKEHTE 145
Q P P+ + V + E ++ ST EKK+Q +PK+ +
Sbjct: 1393 KKDSFSQESSPSSPSDLAKLESTVLSILEAQA-STLADEKSEKKTQPHEVSPEQPKDQEK 1451
Query: 146 PKSLPKQASDTGSNDAHNKKAVSR-------SAEQQPSEKSTEPKTKPQDMISAGGE--- 195
+SL + T S + + R S + PS K + K++ D I+ E
Sbjct: 1452 TQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYD 1511
Query: 196 SVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGK-SGMDAALDDLIDTLGGPEETE 254
SV + P ++K + S+ + E K + G D +I+ + +
Sbjct: 1512 SVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASG 1571
Query: 255 EENTTYTGPEVSDPMSSTYI----EELGKREVTIPPKYRELLAKKEGITGPPADSSKPIG 310
E+ + ++ + SST E GK ++T K+R L K T D+ +
Sbjct: 1572 SEDDEFIRNQLKEISSSTESQKKEETKGKGKIT-AGKHRRLTRKSS--TSIDEDAGRRHS 1628
Query: 311 PDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMS 370
D D + SP ++T+ +ES E++ G R + +E ++
Sbjct: 1629 WHDEDDEAFDE----SPELKYRETKSQESEELVVTGGGGLRRF--------KTIELNSTI 1676
Query: 371 DQALEALSASLGTR---QAEPELDLRSIKEVDEAKAKEE-----------------KLEK 410
A S+ T EPEL++ S+ + E +++ E +
Sbjct: 1677 ADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSS 1736
Query: 411 CGEDDETIPSEYR-----LKPATDKDGKPLLP---EPEEKPKPRSESELIDELSEDFDRS 462
ED ++ PS + + A + PLLP + E+ + R E EL+ E + +
Sbjct: 1737 LDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIE 1796
Query: 463 ECKEKPSKPTEKTEESKAAA 482
+ + K S K ++ + A
Sbjct: 1797 QQQRKSSSKKSKKDKDELRA 1816
Score = 50.4 bits (119), Expect = 6e-06
Identities = 155/777 (19%), Positives = 261/777 (33%), Gaps = 95/777 (12%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ P + P P P + A + HE K+ P+KP + K A +
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHE----KSQPGPAKPPAQPSGLTKPLAQQPGTVKPPV 353
Query: 61 YAGGTASA-------TKVSASSGATSKSSSMNP-TETKAIPVSQQMEGPHLPNKKKHKKQ 112
GT K A + K SS P + A P P K Q
Sbjct: 354 QPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQ 413
Query: 113 AVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHN--------- 163
V T P+ +Q L + P + P +P Q + G A
Sbjct: 414 QVGT-PKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ 472
Query: 164 ----------KKAVSRSAEQQPSEK--------STEPKTKPQDMISAGGESVAGITAISG 205
+ ++ QQP ST+P + + S
Sbjct: 473 LPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQ 532
Query: 206 KPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEV 265
+PG K + +PA P + KP ++G L + ++ + P+
Sbjct: 533 QPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQP-----PTVSPSAKQPPSQGLPKT 587
Query: 266 SDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSS--DFT 323
P+ +T + + +P K + T S P+ + +
Sbjct: 588 ICPLCNT-----TELLLHVPEKANFNTCTECQTT---VCSLCGFNPNPHLTEVKEWLCLN 639
Query: 324 CGSPTAAGKKTEKEESTEVLKAQSAGTVRSAA----PPQEKKRKVEKDTMSDQALEALSA 379
C A G S+ K ++A ++A PQ ++ +KD Q LS
Sbjct: 640 CQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQ---DLSK 696
Query: 380 SLGTRQAEPELDLRSIKEVDEAKAKE----EKLEKCGEDDE-TIPSEYRLKP-ATDKDGK 433
+ ++ P + ++ AKAK+ + L K E ++PSE P A DK +
Sbjct: 697 APEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 434 PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 493
P + +P S + ++ +S+ +EK + P + + + P E V
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 494 SMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 553
A P PA+ + ++S G+K+ DP K K + K + K
Sbjct: 817 D----SKAIPRPASDSKIISHPGPS--SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
Query: 554 GEKEETIPPDYRLEEVKDKDGKPLLPK-ESKEQLPPMSEDFLLDALSEDFSGPQNASSLK 612
K PP R + PK + + + ++ + DA + PQ + K
Sbjct: 871 MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 613 F--EDAKLAAAISEVVSQT----PASTTQAGAPPRDT-SQSDKDLDDALDKLSDSLGQRQ 665
A + + S ++S P S + GAP + + S K S GQ
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPK---STGQAP 987
Query: 666 PDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSE 722
P P ++ P VK++ KA +KL + + P R + KP PP K S+
Sbjct: 988 PAPAKSIP----VKKETKAPAAEKLEPKAEQAPTVKR----TETEKKP--PPIKDSK 1034
Score = 49.3 bits (116), Expect = 1e-05
Identities = 154/740 (20%), Positives = 268/740 (36%), Gaps = 152/740 (20%)
Query: 56 QSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVK 115
Q+ R +G K+ + S PTE+ SQ+ P K ++Q VK
Sbjct: 1110 QTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESS----SQKTAVPPQVKLVKKQEQEVK 1165
Query: 116 TEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQP 175
TE EK V+ EK KE + +P + + + SA Q+
Sbjct: 1166 TEAEK--------VILEKV------KETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211
Query: 176 SEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSG 235
E K P++ E + P DKK ++ T A P E K D KS
Sbjct: 1212 KPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSA-PEEQKHDLL--KSQ 1268
Query: 236 MDAALDDLIDTL-------GGPEETEEEN----TTYTGPEVSDPMSSTYIEE-----LGK 279
+ A + L + G +T+ E T + P+ D + T E+ K
Sbjct: 1269 VQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAK 1328
Query: 280 REVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDA-LSSDFTCGSPTAAGK-----K 333
+ P K + +KE + S +P P D SSD G ++ G+
Sbjct: 1329 PDQVEPGKEK---TEKEDDKSDTSSSQQPKSPQGLSDTGYSSD---GISSSLGEIPSLIP 1382
Query: 334 TEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLR 393
T++++ + LK S S + P + K+E +S LEA +++L ++E +
Sbjct: 1383 TDEKDILKGLKKDSFSQESSPSSPSDLA-KLESTVLS--ILEAQASTLADEKSEKKTQPH 1439
Query: 394 SI-----KEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 448
+ K+ ++ ++ E LE ++E S+ K KD + +P ++ + +
Sbjct: 1440 EVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDH---KEK 1496
Query: 449 SELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATL 508
SE +D+++ +P + EES + +PV + RTS+ S S
Sbjct: 1497 SEFVDDITTR----------REPYDSVEESSESENSPVPQRKRRTSVGSSSS-------- 1538
Query: 509 KGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEE 568
++ K+ED + GE+E+ I +E
Sbjct: 1539 ----------------------------------DEYKQEDSQGSGEEEDFIRKQI-IEM 1563
Query: 569 VKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFE-DAKLAAAISEVVS 627
D+D ++F+ + L E S ++ + + K+ A ++
Sbjct: 1564 SADEDAS-----------GSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLT 1612
Query: 628 QTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHR 687
+ +++ A R S D+D D+A D+ S L R+ E+ E+ V R
Sbjct: 1613 RKSSTSIDEDAGRRH-SWHDED-DEAFDE-SPELKYRETKSQES---EELVVTGGGGLRR 1666
Query: 688 DKLGERDDTIPPEY--------RHLLDDNGQDKPVKPPTKKSEDSKK------------- 726
K E + TI +Y L D + ++ T ED +
Sbjct: 1667 FKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFT 1726
Query: 727 PADDQDPIDALSGDLDSCPS 746
P + +L D DS PS
Sbjct: 1727 PGTSPTSVSSLDEDSDSSPS 1746
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 67.4 bits (163), Expect = 5e-11
Identities = 108/765 (14%), Positives = 248/765 (32%), Gaps = 25/765 (3%)
Query: 28 SEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPT 87
S+ + S S + S + ++ SS SS + + +++++ S SS ++ S S + +
Sbjct: 561 SDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSS 620
Query: 88 ETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPK 147
++K+ + + +K + S + + S + +
Sbjct: 621 DSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSS 680
Query: 148 SLPKQASDTG-SNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGK 206
S +SD+ S+D+ N S S++ S+ S + + S S + ++ S
Sbjct: 681 SDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS-SDSDSSNSSDSSDSSN 739
Query: 207 PGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVS 266
D S + +S S S + D D+ + + N++ + +
Sbjct: 740 SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSN 799
Query: 267 DPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGS 326
SS + + + + + + +DSS D+ D SSD + GS
Sbjct: 800 SSDSSNSSDSSDSSDSS------DSDSSNSSDSSNSSDSSDSSNSSDSSD--SSDSSDGS 851
Query: 327 PTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 386
+ + +++ S++ + + ++ + SD + + S S + +
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNS 911
Query: 387 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPR 446
D + + E+ + + + ++D +
Sbjct: 912 SDSSDSSNSSDSSESSNSSDNSNSSDSSNSS--------DSSDSSDSSNSSDSSNSSDSS 963
Query: 447 SESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA 506
+ S+ D S D S S ++ ++ S ++ + S++ + ++
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN 1023
Query: 507 TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 566
+ + D+ ++ S +D D + + + + + D
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS-- 1081
Query: 567 EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 626
E D S S D + S D S N+S ++ S
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 1141
Query: 627 SQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEH 686
S + S+ + + S D D+ D S D ++ D ++
Sbjct: 1142 SDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1201
Query: 687 RDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPS 746
D D + + + D + S +S +D D D+ + S S
Sbjct: 1202 SDSSDSSDSSDSSD-----SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS 1256
Query: 747 TTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKDD 791
+ S + + D+ + S NG + ++ ++ DD
Sbjct: 1257 DSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 51.6 bits (122), Expect = 3e-06
Identities = 119/777 (15%), Positives = 246/777 (31%), Gaps = 53/777 (6%)
Query: 28 SEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPT 87
S S+S S + D+K G +S + G A S ++ ++ +S N
Sbjct: 439 SNTGSDSNSDGYDSYDFDDKSMQ--GDDPNSSDESNGNDDANSESDNNSSSRGDASYNSD 496
Query: 88 ETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPK 147
E+K N + + + + T S + + + ++
Sbjct: 497 ESK-------------DNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG 543
Query: 148 SLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISA-GGESVAGITAISGK 206
+SD+ S+D+ N S S++ S+ ++ + D S+ +S + ++ S
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD 603
Query: 207 PGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVS 266
D S + +SK D S KS D++ D ++ + + + +
Sbjct: 604 SSDSSDSSDSSDSSDSSDSKSD--SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 267 DPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGS 326
SS + + + + + +DSS D+ D+ SD + S
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSD-----SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 327 PTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQA 386
++ ++ + S + S+ + S+ D+ S S + +
Sbjct: 717 DSSNSNSSDSDSSN---SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 387 EPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPR 446
D + + +++ + + D + S+ + D
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD----SSDSSDSSDSDSSNSSDSSNS 829
Query: 447 SESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA 506
S+S S+ D S+ + + +S ++ + S +S S S E +
Sbjct: 830 SDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Query: 507 TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEETIPPDYRL 566
+ +DS ++D D D + E + + D
Sbjct: 890 NSSDS---------SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 567 EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNAS----------SLKFEDA 616
+S + D+ S D S N+S S D+
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1000
Query: 617 KLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMED 676
++ S+ + +S + + D+S S D D+ D S D ++ D
Sbjct: 1001 SNSSDSSDSSDSSDSSNSSDSSNSSDSSNS-SDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Query: 677 KVKEKAKAEHRDKLGERDDTIPPEYRHLLD-DNGQDKPVKPPTKKSEDSKKPADDQDPID 735
++ D D + E D N D + S DS +D D D
Sbjct: 1060 SSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSD 1119
Query: 736 A--LSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSKPKD 790
+ S DS S+ + + + D + SS + + + + ++S D
Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 67.0 bits (162), Expect = 6e-11
Identities = 101/401 (25%), Positives = 155/401 (38%), Gaps = 65/401 (16%)
Query: 329 AAGKKTEKEESTEVLKAQSAGTVRSAAPP-------------QEKKRKVEKDTMSDQALE 375
AA +K E+ E+ E A V++ AP QE++ + ++ SDQA E
Sbjct: 491 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 550
Query: 376 ALSASLGT------RQAEPELDLRSIKEVDEAK---AKEEKLEKCGEDDETIPSEYRLKP 426
S G+ Q E E + + E EAK EEK E+ +E + KP
Sbjct: 551 GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 610
Query: 427 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAP 485
K P P E+ P +S + ++ +S +EK P K+ E K +P
Sbjct: 611 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV- 669
Query: 486 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKE 543
S P K VP VE +GK E E+ K +VKE
Sbjct: 670 --------------SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKE 711
Query: 544 KAKEEDREKLGEKEETIPPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSED 592
KEE EK EK + +P + E VK+ K K L KE+KE+ P+ ++
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 771
Query: 593 FLLDAL-----SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 647
+ SE+ + A + ED + + E + T + G+ +
Sbjct: 772 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGS---GREEEK 827
Query: 648 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 688
+ + LD LS + ++ D E K + K EK +E D
Sbjct: 828 GVVTNGLD-LSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 867
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/391 (22%), Positives = 138/391 (35%), Gaps = 52/391 (13%)
Query: 316 DALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQA 373
D L+ AA +K + E T G + + PP K++K +
Sbjct: 386 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 445
Query: 374 LEAL---------SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 424
L+ + ++E E L +I E KEEK E E +E +E
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 505
Query: 425 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK---------- 474
A K PE +E+ + E E +E E+ + ++ + +EK
Sbjct: 506 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 565
Query: 475 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 534
EE + A A EA + ++ E AT + V D VE +K P
Sbjct: 566 QEEGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPK 619
Query: 535 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFL 594
PV +K K + E EK ++ P +EE K K P P E K + P
Sbjct: 620 SPVEEKGKSPVPKSPVE---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK---- 671
Query: 595 LDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 654
+ E P S + E+AK A + + Q + P++ K+
Sbjct: 672 -SPVEEKAKSPVPKSPV--EEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKE----- 722
Query: 655 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 685
++ D E K E VKE+A AE
Sbjct: 723 --------EKPKDVPEKKKAESPVKEEAVAE 745
Score = 45.4 bits (106), Expect = 2e-04
Identities = 85/378 (22%), Positives = 150/378 (39%), Gaps = 56/378 (14%)
Query: 89 TKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKS 148
T+ + VS + E +K+ + +A + E K K + E K +EG+ +E E
Sbjct: 477 TEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVK-ATAPEVKEEEGEKEE--EEGQ 533
Query: 149 LPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPG 208
++ D G A S AE+ SEK E ++ ++ GE+ A G+
Sbjct: 534 EEEEEEDEG--------AKSDQAEEGGSEK--EGSSEKEEGEQEEGETEA---EAEGEEA 580
Query: 209 DKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDP 268
+ K+EKK VE K ++ + K EE + + P
Sbjct: 581 EAKEEKK-------VEEKSEEVATK-----------------EELVADAKVEKPEKAKSP 616
Query: 269 MSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPT 328
+ + +EE GK V P E K P + K P ++ SP
Sbjct: 617 VPKSPVEEKGKSPV--PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPV 674
Query: 329 AAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEP 388
K+ +S V +A+S V +E++++V K+ ++ +E ++ E
Sbjct: 675 EEKAKSPVPKS-PVEEAKSKAEVGKGEQKEEEEKEV-KEAPKEEKVE--------KKEEK 724
Query: 389 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 448
D+ K+ E+ KEE + + +++ + L+ T ++GKPL E +EK K E
Sbjct: 725 PKDVPEKKKA-ESPVKEEAVAEVVTITKSV--KVHLEKETKEEGKPLQQE-KEKEKAGGE 780
Query: 449 SELIDELSEDFDRSECKE 466
+E S+ + KE
Sbjct: 781 GGSEEEGSDKGAKGSRKE 798
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/251 (19%), Positives = 90/251 (35%), Gaps = 26/251 (10%)
Query: 29 EKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKS----SSM 84
E +E+ ++ E + +EKK +++ A K + KS
Sbjct: 568 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 627
Query: 85 NPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHT 144
+P + + P P ++K K K+ E+K +S E+K++ PK
Sbjct: 628 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 687
Query: 145 EPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAG---GESVAGIT 201
E + + K+ E++ +K +PK P+ + E+VA +
Sbjct: 688 EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVV 747
Query: 202 AIS--------------GKP--GDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLID 245
I+ GKP +K+KEK E G D A++ ++
Sbjct: 748 TITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVE 807
Query: 246 TLGGPEETEEE 256
G EE E+E
Sbjct: 808 ---GKEEVEQE 815
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 67.0 bits (162), Expect = 6e-11
Identities = 101/401 (25%), Positives = 155/401 (38%), Gaps = 65/401 (16%)
Query: 329 AAGKKTEKEESTEVLKAQSAGTVRSAAPP-------------QEKKRKVEKDTMSDQALE 375
AA +K E+ E+ E A V++ AP QE++ + ++ SDQA E
Sbjct: 115 AAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE 174
Query: 376 ALSASLGT------RQAEPELDLRSIKEVDEAK---AKEEKLEKCGEDDETIPSEYRLKP 426
S G+ Q E E + + E EAK EEK E+ +E + KP
Sbjct: 175 GGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKP 234
Query: 427 ATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTE-ESKAAAPAP 485
K P P E+ P +S + ++ +S +EK P K+ E K +P
Sbjct: 235 EKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV- 293
Query: 486 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALAD--SLGKKEADPEDGKPVMDKVKE 543
S P K VP VE +GK E E+ K +VKE
Sbjct: 294 --------------SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEK----EVKE 335
Query: 544 KAKEEDREKLGEKEETIPPDYRLEE-VKD----------KDGKPLLPKESKEQLPPMSED 592
KEE EK EK + +P + E VK+ K K L KE+KE+ P+ ++
Sbjct: 336 APKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQE 395
Query: 593 FLLDAL-----SEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSD 647
+ SE+ + A + ED + + E + T + G+ +
Sbjct: 396 KEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEV-EGKEEVEQETKEKGS---GREEEK 451
Query: 648 KDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRD 688
+ + LD LS + ++ D E K + K EK +E D
Sbjct: 452 GVVTNGLD-LSPADEKKGGDKSEEKVVVTKTVEKITSEGGD 491
Score = 48.5 bits (114), Expect = 2e-05
Identities = 89/391 (22%), Positives = 138/391 (35%), Gaps = 52/391 (13%)
Query: 316 DALSSDFTCGSPTAAGKKTEKEESTE--VLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQA 373
D L+ AA +K + E T G + + PP K++K +
Sbjct: 10 DLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQKPKVEAPK 69
Query: 374 LEAL---------SASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 424
L+ + ++E E L +I E KEEK E E +E +E
Sbjct: 70 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEE 129
Query: 425 KPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEK---------- 474
A K PE +E+ + E E +E E+ + ++ + +EK
Sbjct: 130 VAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 189
Query: 475 TEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDG 534
EE + A A EA + ++ E AT + V D VE +K P
Sbjct: 190 QEEGETEAEAEGEEAEAKEEK-KVEEKSEEVATKEELVADAKVEK-----PEKAKSPVPK 243
Query: 535 KPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFL 594
PV +K K + E EK ++ P +EE K K P P E K + P
Sbjct: 244 SPVEEKGKSPVPKSPVE---EKGKSPVPKSPVEE-KGKSPVPKSPVEEKGKSPVSK---- 295
Query: 595 LDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL 654
+ E P S + E+AK A + + Q + P++ K+
Sbjct: 296 -SPVEEKAKSPVPKSPV--EEAKSKAEVGK-GEQKEEEEKEVKEAPKEEKVEKKE----- 346
Query: 655 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAE 685
++ D E K E VKE+A AE
Sbjct: 347 --------EKPKDVPEKKKAESPVKEEAVAE 369
Score = 45.4 bits (106), Expect = 2e-04
Identities = 85/378 (22%), Positives = 150/378 (39%), Gaps = 56/378 (14%)
Query: 89 TKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKS 148
T+ + VS + E +K+ + +A + E K K + E K +EG+ +E E
Sbjct: 101 TEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVK-ATAPEVKEEEGEKEE--EEGQ 157
Query: 149 LPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPG 208
++ D G A S AE+ SEK E ++ ++ GE+ A G+
Sbjct: 158 EEEEEEDEG--------AKSDQAEEGGSEK--EGSSEKEEGEQEEGETEA---EAEGEEA 204
Query: 209 DKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDP 268
+ K+EKK VE K ++ + K EE + + P
Sbjct: 205 EAKEEKK-------VEEKSEEVATK-----------------EELVADAKVEKPEKAKSP 240
Query: 269 MSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPT 328
+ + +EE GK V P E K P + K P ++ SP
Sbjct: 241 VPKSPVEEKGKSPV--PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPV 298
Query: 329 AAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEP 388
K+ +S V +A+S V +E++++V K+ ++ +E ++ E
Sbjct: 299 EEKAKSPVPKS-PVEEAKSKAEVGKGEQKEEEEKEV-KEAPKEEKVE--------KKEEK 348
Query: 389 ELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSE 448
D+ K+ E+ KEE + + +++ + L+ T ++GKPL E +EK K E
Sbjct: 349 PKDVPEKKKA-ESPVKEEAVAEVVTITKSV--KVHLEKETKEEGKPLQQE-KEKEKAGGE 404
Query: 449 SELIDELSEDFDRSECKE 466
+E S+ + KE
Sbjct: 405 GGSEEEGSDKGAKGSRKE 422
Score = 42.0 bits (97), Expect = 0.002
Identities = 50/251 (19%), Positives = 90/251 (35%), Gaps = 26/251 (10%)
Query: 29 EKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKS----SSM 84
E +E+ ++ E + +EKK +++ A K + KS
Sbjct: 192 EGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 251
Query: 85 NPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHT 144
+P + + P P ++K K K+ E+K +S E+K++ PK
Sbjct: 252 SPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPV 311
Query: 145 EPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAG---GESVAGIT 201
E + + K+ E++ +K +PK P+ + E+VA +
Sbjct: 312 EEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVV 371
Query: 202 AIS--------------GKP--GDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLID 245
I+ GKP +K+KEK E G D A++ ++
Sbjct: 372 TITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVE 431
Query: 246 TLGGPEETEEE 256
G EE E+E
Sbjct: 432 ---GKEEVEQE 439
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 64.3 bits (155), Expect = 4e-10
Identities = 134/647 (20%), Positives = 234/647 (36%), Gaps = 134/647 (20%)
Query: 68 ATKVSASSGATSKSSSMNPTET------KAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKK 121
A K + ++GAT + ++ + K+ V ++ + P KK KK+A ++ E
Sbjct: 31 ANKFAKATGATQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDS 90
Query: 122 SQSTK-LSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
S+ + + KK+ + P +AS++ S++ + ++QP +K
Sbjct: 91 SEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGV 150
Query: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPA-VPVESK-PDKPSGKS---- 234
+P+ K +S + S + K +K +TP V ++K P KP+ +
Sbjct: 151 KPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIA 210
Query: 235 -GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLA 293
G A+ + +++EEE T + T+P K +++A
Sbjct: 211 NGKAASSSSSSSSSSSSDDSEEEKAAATPKK------------------TVPKK--QVVA 250
Query: 294 KKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRS 353
K P ++ P + + SSD E+EE + +K G S
Sbjct: 251 K-----APVKAATTPTRKSSSSEDSSSD-------------EEEEQKKPMK-NKPGPYSS 291
Query: 354 AAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGE 413
PP K SLGT+ + K V++ + E + E
Sbjct: 292 VPPPSAPPPK---------------KSLGTQPPK--------KAVEKQQPVESSEDSSDE 328
Query: 414 DDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTE 473
D + SE KP T K ++ + KP P ++ S D D SE E PSKP
Sbjct: 329 SDSS--SEEEKKPPT----KAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAG 382
Query: 474 KTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPED 533
T+ S + PA +++ PA P V
Sbjct: 383 TTKNS-SNKPAVTTKS---------------PAVKPAAAPKQPVGG-------------- 412
Query: 534 GKPVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDF 593
G+ ++ + + + E+ E+E+T + K K +Q P S D
Sbjct: 413 GQKLLTRKADSSSSEEESSSSEEEKT---KKMVATTKPKATAKAALSLPAKQAPQGSRDS 469
Query: 594 LLD---ALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDL 650
D + SE+ + S++K + K+A PAS + A ++S SD
Sbjct: 470 SSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG---AAPSKPASAKKGKAESSNSSSSDDSS 526
Query: 651 DDALDKLSDSLGQRQPDPDEN-------------KPMEDKVKEKAKA 684
++ +KL R P N K E++ +EK KA
Sbjct: 527 EEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKA 573
Score = 61.2 bits (147), Expect = 4e-09
Identities = 90/478 (18%), Positives = 167/478 (34%), Gaps = 71/478 (14%)
Query: 10 ASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASAT 69
A P+P RAA + S +S S S + ++ A + + A A
Sbjct: 198 APPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAA 257
Query: 70 KVSASSGATSKSSSMNPTETKAIPVSQQMEGPHL---PNKKKHKKQAVKTEPEKKSQSTK 126
++S+ SS + E + P+ + GP+ P K+++ T+P KK+
Sbjct: 258 TTPTRKSSSSEDSSSDEEEEQKKPMKNK-PGPYSSVPPPSAPPPKKSLGTQPPKKAV--- 313
Query: 127 LSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQP-SEKSTEPKTK 185
++ +P E +E S +S K VS++ + P ++K+ E +
Sbjct: 314 ---------EKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSD 364
Query: 186 PQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLID 245
D S+ + A + K K + +PAV + P +P G L+
Sbjct: 365 SSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG------QKLLT 418
Query: 246 TLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADS 305
+EEE+++ + +++T + K +++P K
Sbjct: 419 RKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAK------------------ 460
Query: 306 SKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 365
P G D+ SSD S +KT K + + + AG + P KK K E
Sbjct: 461 QAPQGSRDS----SSDSDSSSSEEEEEKTSKS-AVKKKPQKVAGGAAPSKPASAKKGKAE 515
Query: 366 KDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLK 425
S D ++ +EEKL+ G P
Sbjct: 516 SSNSSSSD-------------------------DSSEEEEEKLKGKGSPRPQAPKANGTS 550
Query: 426 PATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAP 483
T ++GK EE+ + + + ++ + R + + T + ++ K P
Sbjct: 551 ALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTP 608
Score = 56.6 bits (135), Expect = 9e-08
Identities = 103/484 (21%), Positives = 187/484 (38%), Gaps = 59/484 (12%)
Query: 3 QPGQKP---AASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSR 59
Q G KP AA P++A ++ + SE E P K KA + + +R
Sbjct: 147 QKGVKPQAKAAKAPPKKAKSSDSDSDSSSE--DEPPKNQKPKITPVTVKAQTKAPPKPAR 204
Query: 60 TYAGGTASATKVSASSGATSKSSSMNPTE--------TKAIPVSQ-----QMEGPHLPNK 106
A + K ++SS ++S SSS + +E K +P Q ++ P +
Sbjct: 205 --AAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTR 262
Query: 107 K------------KHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQAS 154
K + +K+ +K +P S S KKS +P + K P ++S
Sbjct: 263 KSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESS 322
Query: 155 DTGSNDAHN----------KKAVSR-SAEQQPSEKSTEPKTKPQDMISAGGESVAGITAI 203
+ S+++ + K VS+ + + P++K+ E + D S+ + A
Sbjct: 323 EDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAG 382
Query: 204 SGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGP 263
+ K K + +PAV + P +P G L+ +EEE+++
Sbjct: 383 TTKNSSNKPAVTTKSPAVKPAAAPKQPVGGG------QKLLTRKADSSSSEEESSSSEEE 436
Query: 264 EVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFT 323
+ +++T + K +++P K +G +DS ++ + S
Sbjct: 437 KTKKMVATTKPKATAKAALSLPAK-----QAPQGSRDSSSDSDSSSSEEEE-EKTSKSAV 490
Query: 324 CGSP--TAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE-KDTMSDQALEALSAS 380
P A G K S + KA+S+ + S +E++ K++ K + QA +A S
Sbjct: 491 KKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTS 550
Query: 381 LGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPE 440
T Q + S +E +E K + K G + +E + T + K L P
Sbjct: 551 ALTAQ-NGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPN 609
Query: 441 EKPK 444
PK
Sbjct: 610 TFPK 613
Score = 55.8 bits (133), Expect = 1e-07
Identities = 84/379 (22%), Positives = 139/379 (36%), Gaps = 67/379 (17%)
Query: 461 RSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL 520
+++ K S + +EE + P +A + PP A K + + E+
Sbjct: 77 KAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGL---PPGKAAAKASESSSSEESS 133
Query: 521 ADSLGKKEADPEDGK--PVMDKVKEKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLL 578
D D ED K PV VK +AK K D E+ K+ KP +
Sbjct: 134 DDD------DEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKI 187
Query: 579 -----------PKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVS 627
P + P ++ A S S ++SS E+ K AA + V
Sbjct: 188 TPVTVKAQTKAPPKPARAAPKIANG---KAASSSSSSSSSSSSDDSEEEKAAATPKKTVP 244
Query: 628 Q----TPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQ-----------PDPDEN- 671
+ A A P R +S S+ D ++ + + P P ++
Sbjct: 245 KKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL 304
Query: 672 --KPMEDKVKEKAKAEHRDKLGERDDTIPPEYRH----LLDDNGQDKPVKPPTKKSEDSK 725
+P + V+++ E + + D+ E + + KP PP KK+ +S
Sbjct: 305 GTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP--PPAKKAAESS 362
Query: 726 KPADDQDPIDALSGDLDSCPS----TTETSQN----TAKDKCKKAASSSKAPKNGG---- 773
+ D D S + D PS TT+ S N T K K A++ K P GG
Sbjct: 363 SDSSDSD-----SSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 774 -KAKDSAKTTEETSKPKDD 791
+ DS+ + EE+S +++
Sbjct: 418 TRKADSSSSEEESSSSEEE 436
Score = 52.8 bits (125), Expect = 1e-06
Identities = 126/577 (21%), Positives = 202/577 (35%), Gaps = 71/577 (12%)
Query: 4 PGQKPAASPR-----PRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSS 58
P K AA P P AAA+ + SE++S+ + +KK +K
Sbjct: 100 PPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGV--------- 150
Query: 59 RTYAGGTASATKVSASSGATSKSSSMN--PTETK----AIPVSQQMEGPHLPNKKKHK-K 111
+ A + K + SS + S SSS + P K + V Q + P P + K
Sbjct: 151 KPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIA 210
Query: 112 QAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSA 171
S S+ S E++ PK+ K + +A + K + S +
Sbjct: 211 NGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDS 270
Query: 172 EQQPSEKSTEP-KTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKP 230
E+ +P K KP S S G KK +K PVES D
Sbjct: 271 SSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQ----QPVESSEDS- 325
Query: 231 SGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRE 290
D D+ E+ + P + E + + E
Sbjct: 326 ----------SDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE 375
Query: 291 LLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKK-TEKEESTEVLKAQSAG 349
+K G T S+KP A+++ P AA K+ + KA S+
Sbjct: 376 APSKPAGTT--KNSSNKP--------AVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSS 425
Query: 350 TVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLE 409
+ ++ +E+K K T +A + SL +QA P+ S + D + ++E
Sbjct: 426 SEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQA-PQGSRDSSSDSDSSSSEE---- 480
Query: 410 KCGEDDETIPSEYRLKPATDKDG-KPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKP 468
E+++T S + KP G P P +K K S + S+D E ++
Sbjct: 481 ---EEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSN---SSSSDDSSEEEEEKLK 534
Query: 469 SKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKK- 527
K + + + KA S + + S E K V V + + SL K+
Sbjct: 535 GKGSPRPQAPKANG---TSALTAQNGKAAKNSEEEEEEKKKAAV----VVSKSGSLKKRK 587
Query: 528 --EADPEDGKPVMDKVK-EKAKEEDREKLGEKEETIP 561
EA E P K+K + + K GEK + P
Sbjct: 588 QNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSP 624
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 63.9 bits (154), Expect = 5e-10
Identities = 118/573 (20%), Positives = 210/573 (36%), Gaps = 71/573 (12%)
Query: 25 EHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSM 84
E EK S + P + E A++ SS S + + +S+ S SS + S+ +
Sbjct: 438 EQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENE- 496
Query: 85 NPTETKAI----PVSQQME---------GPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVH 131
P ET A P + + + P P + + + PE K S +
Sbjct: 497 -PLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQE 555
Query: 132 EKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS-AEQQPSEKSTEPKTKPQDMI 190
+S++ PK ++ P +A G K++ +S A+Q+P ++ T +P+ +
Sbjct: 556 HSESKDPPPKSSSKAPRAPPEAPHPG------KRSCQKSPAQQEPPQRQTVGTKQPKKPV 609
Query: 191 SAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKS-GMDAALDDLIDTLGG 249
A + T++ G ++E L ++ DKP K+ G A
Sbjct: 610 KASARA-GSRTSLQG-----EREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAV 663
Query: 250 PEETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPI 309
P +E++ + P S +S + + T P++ L+ E GPP S
Sbjct: 664 PPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRT--PEHFALVPLTES-QGPPHSGSG-- 718
Query: 310 GPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLK-AQSAGTVRSAAPPQEKKRKVEKDT 368
S C + + K+ L+ + +R PPQ K+ D
Sbjct: 719 ---------SRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDL 769
Query: 369 MSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPA- 427
+S G+RQ R ++ K+ EK D + ++ R A
Sbjct: 770 LS---RIPQPPGKGSRQ-------RKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAE 819
Query: 428 TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVS 487
D D K + E E K + S S E S K KPS+P+ ++ + + P PVS
Sbjct: 820 RDCDNKKIRLEKEIKSQSSSSSSSHKESS--------KTKPSRPSSQSSKKEMLPPPPVS 871
Query: 488 EAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKE 547
+ + + +++ + E T P A K + P +V+ K
Sbjct: 872 SSSQKPAKPALKRSRREADTCGQDPPKSASST-------KSNHKDSSIPKQRRVEGKGSR 924
Query: 548 EDREKLGEKEETIPPDYRLEEVKDKDGKPLLPK 580
E G +T P + + + + + KP P+
Sbjct: 925 SSSEHKGSSGDTANP-FPVPSLPNGNSKPGKPQ 956
Score = 56.6 bits (135), Expect = 9e-08
Identities = 107/476 (22%), Positives = 180/476 (37%), Gaps = 55/476 (11%)
Query: 353 SAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG 412
S+APP + E A + + S T ++ D S +++ E
Sbjct: 447 SSAPPSAPQSLPEPVA---SAHSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAP 503
Query: 413 EDDETIPSEYRLKPATDKDGKPLLPEPE-----EKPKPRSESELIDELSEDFDRSECKEK 467
E + ++++L K +P P PE E P+ ES+ + + + SE K+
Sbjct: 504 EPEPPTTNKWQLDNWLTKVSQPAAP-PEGPRSTEPPRRHPESKGSSDSATSQEHSESKDP 562
Query: 468 PSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADS---- 523
P K + K + AP P + C+ S Q PP+ T+ P V+A A +
Sbjct: 563 PPKSSSKAPRAPPEAPHP-GKRSCQKS--PAQQEPPQRQTVGTKQPKKPVKASARAGSRT 619
Query: 524 --LGKKEAD--PEDGKPVMDKVKEKAKEEDREKL---GEKEETIPPDYRLEEVKDKDGKP 576
G++E P + K K K K + R + E + +PP E+ K K P
Sbjct: 620 SLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVPPS--SEKKKHKSSLP 677
Query: 577 LL------PKESKEQLPPMS-EDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQ- 628
P+ +K+ + + E F L L+E P + S + + A + E +
Sbjct: 678 APSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKD 737
Query: 629 ---TPASTTQAGAPPRDT----SQSDKDLDDALDKLSD--SLGQRQPDPDENKPMEDK-- 677
P T+ +P RDT S K D L ++ G RQ ++ +P K
Sbjct: 738 RLPLPLRDTKLLSPLRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKH 797
Query: 678 VKEKAKAEHRDKLGERDDTIPPEYRHLLDDN--GQDKPVKPPTKKSEDSKKPADDQDP-- 733
EK ++ KL ++ E D+ +K +K + S S K + P
Sbjct: 798 SSEKRSSDSSSKLAKKR---KGEAERDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSR 854
Query: 734 --IDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK 787
+ ++ P + +SQ AK K+ S +A G SA +T+ K
Sbjct: 855 PSSQSSKKEMLPPPPVSSSSQKPAKPALKR--SRREADTCGQDPPKSASSTKSNHK 908
Score = 37.7 bits (86), Expect = 0.042
Identities = 52/214 (24%), Positives = 83/214 (38%), Gaps = 38/214 (17%)
Query: 32 SESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKA 91
S P PG KGS ++KA + + AG S+ K SS ++SK + E +
Sbjct: 771 SRIPQPPG--KGSRQRKA------EDKQPPAGKKHSSEK--RSSDSSSKLAKKRKGEAER 820
Query: 92 IPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEK--KSQEGKPKEHTEPKSL 149
NKK ++ E E KSQS+ S H++ K++ +P + K +
Sbjct: 821 ----------DCDNKK------IRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEM 864
Query: 150 PKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGD 209
+ S+ K A+ RS + + PK+ + S+ + GK
Sbjct: 865 LPPPPVSSSSQKPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSR 924
Query: 210 KKKEKKSLT---------PAVP-VESKPDKPSGK 233
E K + P++P SKP KP K
Sbjct: 925 SSSEHKGSSGDTANPFPVPSLPNGNSKPGKPQVK 958
Score = 35.0 bits (79), Expect = 0.27
Identities = 46/202 (22%), Positives = 69/202 (34%), Gaps = 41/202 (20%)
Query: 606 QNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPP----------------RDTSQSDKD 649
Q SS+ +D +L+ + QTP + APP S+S D
Sbjct: 417 QGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSD 476
Query: 650 LDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNG 709
D + D S+S D +EN+P+E E PP DN
Sbjct: 477 SDSSSDSESES---SSSDSEENEPLETPAPEPE---------------PPTTNKWQLDNW 518
Query: 710 QDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAP 769
K +P + P S D + TSQ ++ K SSSKAP
Sbjct: 519 LTKVSQPAAPPEGPRSTEPPRRHPESKGSSD-------SATSQEHSESKDPPPKSSSKAP 571
Query: 770 KNGGKAKDSAKTTEETSKPKDD 791
+ +A K + + S + +
Sbjct: 572 RAPPEAPHPGKRSCQKSPAQQE 593
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 63.5 bits (153), Expect = 7e-10
Identities = 156/775 (20%), Positives = 253/775 (32%), Gaps = 91/775 (11%)
Query: 37 KPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSG-----ATSKSSSMNPTETKA 91
+P SD K SL ++ + T + K +++ G + ++ S+ T K
Sbjct: 127 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 186
Query: 92 IPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPK 151
+ + ++ P + K T P++ + +T K+ PKE T P ++ K
Sbjct: 187 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTP------KEPASTTPKEPT-PTTI-K 238
Query: 152 QASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKK 211
A T A ++SA P E + P T + + E T +P
Sbjct: 239 SAPTTPKEPA---PTTTKSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTK---EPAPTT 290
Query: 212 KEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSS 271
+ TP P + P KP+ + + P T + T T P+ P +
Sbjct: 291 TKSAPTTPKEPAPTTPKKPAPTTPKE------------PAPTTPKEPTPTTPKEPAPTTK 338
Query: 272 TYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAG 331
K PK KE PA P P + + + + +P
Sbjct: 339 EPAPTTPKEPAPTAPKKPAPTTPKE-----PA----PTTPKEPAPTTTKEPSPTTPKEPA 389
Query: 332 KKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD----TMSDQALEALSASLGTRQAE 387
T K T + T + P+E K+ T + A T E
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 449
Query: 388 PELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP-----EEK 442
P + KE K+ E T P E P T K P PE EK
Sbjct: 450 PAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE--TAPTTPKKLTPTTPEKLAPTTPEK 505
Query: 443 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSA 501
P P + EL E+ P+ P E + KAAAP E T +
Sbjct: 506 PAPTTPEELAPTTPEE-------PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 558
Query: 502 PPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 559
P EPA T K T P + A + K+ A KP ++ +E +K
Sbjct: 559 PKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617
Query: 560 IPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMSEDFLLDALSEDFSGPQNASSLKFE 614
P K P PKE KE P + L E P + K
Sbjct: 618 TTP---------KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAPTTPKKPA 664
Query: 615 DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM 674
+LA ++ + T + P + K+ K P P ++
Sbjct: 665 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 675 EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKP--PTKKSEDSKKPADDQD 732
++ H+ D++ P ++ P +P PT K+ + KP
Sbjct: 725 TPTTTKEPTTIHKSP----DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780
Query: 733 PIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETS 786
D + DL + P TT + K+ ++++ + ++ TT++T+
Sbjct: 781 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 835
Score = 52.4 bits (124), Expect = 2e-06
Identities = 135/644 (20%), Positives = 220/644 (34%), Gaps = 101/644 (15%)
Query: 12 PRPRRAAAARRTHEHVSEKTSE--SPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASAT 69
P P +A T + S T++ +P+ P E + KK A + + T A T
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462
Query: 70 KVSASSGATSKSSSMNPTET------KAIPVSQQMEGPHLPNKKKHK--KQAVKTEPEKK 121
+ + + P ET K P + + P P K ++ T PE+
Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522
Query: 122 SQST--KLSVVHEKKSQEGKPKEH--TEPK----SLPKQASDTGSNDAH--NKKAVSRSA 171
+ +T + + K + PKE T PK + PK+ + T + K + +
Sbjct: 523 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 582
Query: 172 EQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKP----GDKKKEKKSLTPAVPVESKP 227
++P+ +T K P+++ + T P G K P P E P
Sbjct: 583 LKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 641
Query: 228 DKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIP 285
P G + + T P E TT GP SD + T +E T P
Sbjct: 642 TTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---TTP 697
Query: 286 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 345
+ KK T P P +S+ T PT K + EST L A
Sbjct: 698 KEPAPTTPKKPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSA 748
Query: 346 QSAGTVRSAAP-----PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDE 400
+ +P P K K M+ A + + E DLR+ E
Sbjct: 749 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT----------ERDLRTTPETTT 798
Query: 401 AKAKEEKLEKCGEDDETIPSEY-----RLKPATDKDGKP----------LLPEPEEKPKP 445
A K K E ++T S+ ++ T +D P L P+ K
Sbjct: 799 AAPKMTK-ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 857
Query: 446 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ------ 499
+ +E++++ E+ +KP ++ SKA P P S +
Sbjct: 858 ITTTEIMNK----------PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP 907
Query: 500 -----SAPPEPATLKGTVPD-DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 553
P P + T+P+ + +A+++ + P P V+ K ED
Sbjct: 908 RVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ-TPNSKLVEVNPKSEDAG-- 964
Query: 554 GEKEET-----IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 592
G + ET P + E D D P +P + P +S++
Sbjct: 965 GAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1008
Score = 50.4 bits (119), Expect = 6e-06
Identities = 101/497 (20%), Positives = 164/497 (32%), Gaps = 36/497 (7%)
Query: 307 KPIGPDDAIDALSS-DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 365
KP D+A L + DF +P + + K ++ + R + PP K
Sbjct: 81 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 140
Query: 366 KDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 424
T++ + +E + +Q + KE + + + +EK D S+
Sbjct: 141 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 195
Query: 425 KPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 481
KP + P L P+E P P + E ++ + K P+ P E + +
Sbjct: 196 KPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 482 APAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 541
AP E T+ + P EPA P A + K+ A KP
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 542 KEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLL 595
KE A +E +E P K+ P PK+ KE P ++
Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374
Query: 596 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDD 652
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 375 TTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 428
Query: 653 ALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 711
K ++P P K P KE A + + T P E
Sbjct: 429 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAP 484
Query: 712 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 771
K T + + P + P +L P+T E T ++ + AP
Sbjct: 485 TTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT 542
Query: 772 GGKAKDSAKTTEETSKP 788
K+ A TT + P
Sbjct: 543 ---PKEPAPTTPKEPAP 556
Score = 44.3 bits (103), Expect = 4e-04
Identities = 57/267 (21%), Positives = 93/267 (34%), Gaps = 15/267 (5%)
Query: 299 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 358
T P ++KPI P ++ S S T + T + + T Q++ +
Sbjct: 114 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 173
Query: 359 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 418
++ + +EK + D A + + T +AE ++ E K E
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233
Query: 419 PSEYRLKPATDKDGKPL------------LPEPEEKPKPRSESELIDELSEDFDRSECKE 466
P+ + P T K+ P P ++P P + E +++ + K
Sbjct: 234 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293
Query: 467 KPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSAPPEPA-TLKGTVPDDAVEALADSL 524
P+ P E + K AP E T + P EPA T K P E A +
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTA 352
Query: 525 GKKEADPEDGKPVMDKVKEKAKEEDRE 551
KK A +P KE A +E
Sbjct: 353 PKKPAPTTPKEPAPTTPKEPAPTTTKE 379
Score = 32.3 bits (72), Expect = 1.8
Identities = 40/241 (16%), Positives = 89/241 (36%), Gaps = 11/241 (4%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P P P+ A + +P+ P E + K+ A + + T
Sbjct: 652 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIP-VSQQMEGPHLPNKKKHK-----KQAV 114
T ++ T + ++++ + ++ P +S + L N K K
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 771
Query: 115 KTEPEK----KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS 170
T+PE K ++T+ + ++ PK E + ++ +++ + + +
Sbjct: 772 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 831
Query: 171 AEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKP 230
+ P + +T T ++ +++ T I KP + K K T + KP KP
Sbjct: 832 QDTTPFKITTLKTTTLAPKVTTTKKTIT-TTEIMNKPEETAKPKDRATNSKATTPKPQKP 890
Query: 231 S 231
+
Sbjct: 891 T 891
Score = 32.0 bits (71), Expect = 2.3
Identities = 54/255 (21%), Positives = 93/255 (36%), Gaps = 21/255 (8%)
Query: 543 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 602
E+ +E D + +K + PDY + KD K K+ PP+ + E
Sbjct: 38 ERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPV--------VDEAG 89
Query: 603 SGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--SQSDKDLDDALDKLSDS 660
SG N K + VS +P TT PR + SD + +L ++
Sbjct: 90 SGLDN-GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 148
Query: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--IPPEYRHLLDDNGQ-DKPVKPP 717
+ + NK KEK + + E+ + P + L + + K P
Sbjct: 149 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 208
Query: 718 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKC----KKAASSSKAPKNGG 773
+ P ++P A + + P+T +++ T K+ K A ++ K P
Sbjct: 209 ALTTPKEPTPTTPKEP--ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PT 265
Query: 774 KAKDSAKTTEETSKP 788
K+ A TT + P
Sbjct: 266 TTKEPAPTTPKEPAP 280
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 63.5 bits (153), Expect = 7e-10
Identities = 156/775 (20%), Positives = 253/775 (32%), Gaps = 91/775 (11%)
Query: 37 KPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSG-----ATSKSSSMNPTETKA 91
+P SD K SL ++ + T + K +++ G + ++ S+ T K
Sbjct: 168 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 227
Query: 92 IPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPK 151
+ + ++ P + K T P++ + +T K+ PKE T P ++ K
Sbjct: 228 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTP------KEPASTTPKEPT-PTTI-K 279
Query: 152 QASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKK 211
A T A ++SA P E + P T + + E T +P
Sbjct: 280 SAPTTPKEPA---PTTTKSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTK---EPAPTT 331
Query: 212 KEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSS 271
+ TP P + P KP+ + + P T + T T P+ P +
Sbjct: 332 TKSAPTTPKEPAPTTPKKPAPTTPKE------------PAPTTPKEPTPTTPKEPAPTTK 379
Query: 272 TYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAG 331
K PK KE PA P P + + + + +P
Sbjct: 380 EPAPTTPKEPAPTAPKKPAPTTPKE-----PA----PTTPKEPAPTTTKEPSPTTPKEPA 430
Query: 332 KKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD----TMSDQALEALSASLGTRQAE 387
T K T + T + P+E K+ T + A T E
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 490
Query: 388 PELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP-----EEK 442
P + KE K+ E T P E P T K P PE EK
Sbjct: 491 PAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE--TAPTTPKKLTPTTPEKLAPTTPEK 546
Query: 443 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSA 501
P P + EL E+ P+ P E + KAAAP E T +
Sbjct: 547 PAPTTPEELAPTTPEE-------PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 599
Query: 502 PPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 559
P EPA T K T P + A + K+ A KP ++ +E +K
Sbjct: 600 PKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658
Query: 560 IPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMSEDFLLDALSEDFSGPQNASSLKFE 614
P K P PKE KE P + L E P + K
Sbjct: 659 TTP---------KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAPTTPKKPA 705
Query: 615 DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM 674
+LA ++ + T + P + K+ K P P ++
Sbjct: 706 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 675 EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKP--PTKKSEDSKKPADDQD 732
++ H+ D++ P ++ P +P PT K+ + KP
Sbjct: 766 TPTTTKEPTTIHKSP----DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821
Query: 733 PIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETS 786
D + DL + P TT + K+ ++++ + ++ TT++T+
Sbjct: 822 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 876
Score = 52.4 bits (124), Expect = 2e-06
Identities = 135/644 (20%), Positives = 220/644 (34%), Gaps = 101/644 (15%)
Query: 12 PRPRRAAAARRTHEHVSEKTSE--SPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASAT 69
P P +A T + S T++ +P+ P E + KK A + + T A T
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503
Query: 70 KVSASSGATSKSSSMNPTET------KAIPVSQQMEGPHLPNKKKHK--KQAVKTEPEKK 121
+ + + P ET K P + + P P K ++ T PE+
Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563
Query: 122 SQST--KLSVVHEKKSQEGKPKEH--TEPK----SLPKQASDTGSNDAH--NKKAVSRSA 171
+ +T + + K + PKE T PK + PK+ + T + K + +
Sbjct: 564 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 623
Query: 172 EQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKP----GDKKKEKKSLTPAVPVESKP 227
++P+ +T K P+++ + T P G K P P E P
Sbjct: 624 LKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 682
Query: 228 DKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIP 285
P G + + T P E TT GP SD + T +E T P
Sbjct: 683 TTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---TTP 738
Query: 286 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 345
+ KK T P P +S+ T PT K + EST L A
Sbjct: 739 KEPAPTTPKKPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSA 789
Query: 346 QSAGTVRSAAP-----PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDE 400
+ +P P K K M+ A + + E DLR+ E
Sbjct: 790 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT----------ERDLRTTPETTT 839
Query: 401 AKAKEEKLEKCGEDDETIPSEY-----RLKPATDKDGKP----------LLPEPEEKPKP 445
A K K E ++T S+ ++ T +D P L P+ K
Sbjct: 840 AAPKMTK-ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 898
Query: 446 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ------ 499
+ +E++++ E+ +KP ++ SKA P P S +
Sbjct: 899 ITTTEIMNK----------PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP 948
Query: 500 -----SAPPEPATLKGTVPD-DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 553
P P + T+P+ + +A+++ + P P V+ K ED
Sbjct: 949 RVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ-TPNSKLVEVNPKSEDAG-- 1005
Query: 554 GEKEET-----IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 592
G + ET P + E D D P +P + P +S++
Sbjct: 1006 GAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1049
Score = 50.4 bits (119), Expect = 6e-06
Identities = 101/497 (20%), Positives = 164/497 (32%), Gaps = 36/497 (7%)
Query: 307 KPIGPDDAIDALSS-DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 365
KP D+A L + DF +P + + K ++ + R + PP K
Sbjct: 122 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKET 181
Query: 366 KDTMSDQA-LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRL 424
T++ + +E + +Q + KE + + + +EK D S+
Sbjct: 182 SLTVNKETTVETKETTTTNKQTSTDG-----KEKTTSAKETQSIEKTSAKDLAPTSKVLA 236
Query: 425 KPATDKDGK---PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAA 481
KP + P L P+E P P + E ++ + K P+ P E + +
Sbjct: 237 KPTPKAETTTKGPALTTPKE-PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 482 APAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKV 541
AP E T+ + P EPA P A + K+ A KP
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 542 KEKAKEEDREKL-GEKEETIPPDYRLEEVKDKDGKPLLPKE-----SKEQLPPMSEDFLL 595
KE A +E +E P K+ P PK+ KE P ++
Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415
Query: 596 DALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAP--PRDTS-QSDKDLDD 652
E + + E A + ++ PA TT AP P++ S + K+
Sbjct: 416 TTTKEP------SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP 469
Query: 653 ALDKLSDSLGQRQPDPDENK-PMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 711
K ++P P K P KE A + + T P E
Sbjct: 470 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK----KPAPTTPKEPAPTTPKETAP 525
Query: 712 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 771
K T + + P + P +L P+T E T ++ + AP
Sbjct: 526 TTPKKLTPTTPEKLAPTTPEKPAPTTPEEL--APTTPEEPTPTTPEEPAPTTPKAAAPNT 583
Query: 772 GGKAKDSAKTTEETSKP 788
K+ A TT + P
Sbjct: 584 ---PKEPAPTTPKEPAP 597
Score = 44.3 bits (103), Expect = 4e-04
Identities = 57/267 (21%), Positives = 93/267 (34%), Gaps = 15/267 (5%)
Query: 299 TGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQ 358
T P ++KPI P ++ S S T + T + + T Q++ +
Sbjct: 155 TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 214
Query: 359 EKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETI 418
++ + +EK + D A + + T +AE ++ E K E
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274
Query: 419 PSEYRLKPATDKDGKPL------------LPEPEEKPKPRSESELIDELSEDFDRSECKE 466
P+ + P T K+ P P ++P P + E +++ + K
Sbjct: 275 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334
Query: 467 KPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSAPPEPA-TLKGTVPDDAVEALADSL 524
P+ P E + K AP E T + P EPA T K P E A +
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP-APTA 393
Query: 525 GKKEADPEDGKPVMDKVKEKAKEEDRE 551
KK A +P KE A +E
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTKE 420
Score = 32.3 bits (72), Expect = 1.8
Identities = 40/241 (16%), Positives = 89/241 (36%), Gaps = 11/241 (4%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P P P+ A + +P+ P E + K+ A + + T
Sbjct: 693 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIP-VSQQMEGPHLPNKKKHK-----KQAV 114
T ++ T + ++++ + ++ P +S + L N K K
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 812
Query: 115 KTEPEK----KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS 170
T+PE K ++T+ + ++ PK E + ++ +++ + + +
Sbjct: 813 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 872
Query: 171 AEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKP 230
+ P + +T T ++ +++ T I KP + K K T + KP KP
Sbjct: 873 QDTTPFKITTLKTTTLAPKVTTTKKTIT-TTEIMNKPEETAKPKDRATNSKATTPKPQKP 931
Query: 231 S 231
+
Sbjct: 932 T 932
Score = 32.0 bits (71), Expect = 2.3
Identities = 54/255 (21%), Positives = 93/255 (36%), Gaps = 21/255 (8%)
Query: 543 EKAKEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDF 602
E+ +E D + +K + PDY + KD K K+ PP+ + E
Sbjct: 79 ERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKKPTPKPPV--------VDEAG 130
Query: 603 SGPQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDT--SQSDKDLDDALDKLSDS 660
SG N K + VS +P TT PR + SD + +L ++
Sbjct: 131 SGLDN-GDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 189
Query: 661 LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDT--IPPEYRHLLDDNGQ-DKPVKPP 717
+ + NK KEK + + E+ + P + L + + K P
Sbjct: 190 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 249
Query: 718 TKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKC----KKAASSSKAPKNGG 773
+ P ++P A + + P+T +++ T K+ K A ++ K P
Sbjct: 250 ALTTPKEPTPTTPKEP--ASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA-PT 306
Query: 774 KAKDSAKTTEETSKP 788
K+ A TT + P
Sbjct: 307 TTKEPAPTTPKEPAP 321
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 63.5 bits (153), Expect = 7e-10
Identities = 156/775 (20%), Positives = 253/775 (32%), Gaps = 91/775 (11%)
Query: 37 KPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSG-----ATSKSSSMNPTETKA 91
+P SD K SL ++ + T + K +++ G + ++ S+ T K
Sbjct: 220 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 279
Query: 92 IPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPK 151
+ + ++ P + K T P++ + +T K+ PKE T P ++ K
Sbjct: 280 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTP------KEPASTTPKEPT-PTTI-K 331
Query: 152 QASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKK 211
A T A ++SA P E + P T + + E T +P
Sbjct: 332 SAPTTPKEPA---PTTTKSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTK---EPAPTT 383
Query: 212 KEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSS 271
+ TP P + P KP+ + + P T + T T P+ P +
Sbjct: 384 TKSAPTTPKEPAPTTPKKPAPTTPKE------------PAPTTPKEPTPTTPKEPAPTTK 431
Query: 272 TYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAG 331
K PK KE PA P P + + + + +P
Sbjct: 432 EPAPTTPKEPAPTAPKKPAPTTPKE-----PA----PTTPKEPAPTTTKEPSPTTPKEPA 482
Query: 332 KKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD----TMSDQALEALSASLGTRQAE 387
T K T + T + P+E K+ T + A T E
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 542
Query: 388 PELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP-----EEK 442
P + KE K+ E T P E P T K P PE EK
Sbjct: 543 PAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE--TAPTTPKKLTPTTPEKLAPTTPEK 598
Query: 443 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSA 501
P P + EL E+ P+ P E + KAAAP E T +
Sbjct: 599 PAPTTPEELAPTTPEE-------PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 651
Query: 502 PPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 559
P EPA T K T P + A + K+ A KP ++ +E +K
Sbjct: 652 PKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710
Query: 560 IPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMSEDFLLDALSEDFSGPQNASSLKFE 614
P K P PKE KE P + L E P + K
Sbjct: 711 TTP---------KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAPTTPKKPA 757
Query: 615 DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM 674
+LA ++ + T + P + K+ K P P ++
Sbjct: 758 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 817
Query: 675 EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKP--PTKKSEDSKKPADDQD 732
++ H+ D++ P ++ P +P PT K+ + KP
Sbjct: 818 TPTTTKEPTTIHKSP----DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873
Query: 733 PIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETS 786
D + DL + P TT + K+ ++++ + ++ TT++T+
Sbjct: 874 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 928
Score = 62.8 bits (151), Expect = 1e-09
Identities = 190/927 (20%), Positives = 288/927 (31%), Gaps = 171/927 (18%)
Query: 8 PAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKG---------SDEKKAASLGSSQSS 58
P + P ++A + + T SP P +KK ++E + S SS
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128
Query: 59 RTYAGGTASATKVSASSGATS----------KSSSMNPTETKAIP----VSQQMEGPHLP 104
+ + +++ K+ +S + + K + N T+ K P V + G
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 188
Query: 105 NKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNK 164
+ K T+ K S S K++ + P K + + +
Sbjct: 189 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKET 248
Query: 165 KAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDK------------KK 212
++ EK+T K + Q + + +A + + KP K K
Sbjct: 249 TTTNKQTSTDGKEKTTSAK-ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 307
Query: 213 EKKSLTPAVPVESKPDKPSG---KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVS--- 266
E TP P + P +P+ KS + T T +E T E +
Sbjct: 308 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 367
Query: 267 --DPMSSTYIE---ELGKREVTIPPKYRELLAKKEGITGP------------------PA 303
+P +T E K T P + KK T P PA
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 427
Query: 304 DSSK---PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAP---- 356
++K P P + +P T KE + K S T + AP
Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 487
Query: 357 --PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLR------------SIKEVDEAK 402
P K T S + T++ P + KE
Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547
Query: 403 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKP-------------LLPEPEEKPKPRSES 449
KE + T P E P T K+ P L P EKP P +
Sbjct: 548 PKEPAPTTTKKPAPTTPKE--PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605
Query: 450 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA--- 506
EL E+ P +P T KAAAP E T + P EPA
Sbjct: 606 ELAPTTPEE----PTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659
Query: 507 -------TLKGTVP------------DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKE 547
T KGT P A + LA + K+ KP K A
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 719
Query: 548 EDRE--KLGEKEETIPPDYRLEEVKDKDGKPLLPKE-SKEQLPPMSEDFLLDALSE---D 601
+E KE K+ P PK+ + ++L P + S+
Sbjct: 720 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779
Query: 602 FSGPQNASSLKFEDAKLA-AAISEVVSQTPASTTQAGAPPRDTSQS---DKDLDDALDKL 657
+ + A + E A + +TP TT + P T + K D++ +L
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Query: 658 SDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGERDDTIPPEYRHLLDDN 708
S + P EN P E V K + +DK ERD PE
Sbjct: 840 S---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 895
Query: 709 GQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKA 768
K T+K+ +SK A + T+ T+Q+T K +++ A
Sbjct: 896 -MTKETATTTEKTTESKITA-------------TTTQVTSTTTQDTTPFKITTLKTTTLA 941
Query: 769 PKNGGKAKDSAKT-----TEETSKPKD 790
PK K T EET+KPKD
Sbjct: 942 PKVTTTKKTITTTEIMNKPEETAKPKD 968
Score = 52.4 bits (124), Expect = 2e-06
Identities = 135/644 (20%), Positives = 220/644 (34%), Gaps = 101/644 (15%)
Query: 12 PRPRRAAAARRTHEHVSEKTSE--SPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASAT 69
P P +A T + S T++ +P+ P E + KK A + + T A T
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555
Query: 70 KVSASSGATSKSSSMNPTET------KAIPVSQQMEGPHLPNKKKHK--KQAVKTEPEKK 121
+ + + P ET K P + + P P K ++ T PE+
Sbjct: 556 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615
Query: 122 SQST--KLSVVHEKKSQEGKPKEH--TEPK----SLPKQASDTGSNDAH--NKKAVSRSA 171
+ +T + + K + PKE T PK + PK+ + T + K + +
Sbjct: 616 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 675
Query: 172 EQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKP----GDKKKEKKSLTPAVPVESKP 227
++P+ +T K P+++ + T P G K P P E P
Sbjct: 676 LKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 734
Query: 228 DKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIP 285
P G + + T P E TT GP SD + T +E T P
Sbjct: 735 TTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---TTP 790
Query: 286 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 345
+ KK T P P +S+ T PT K + EST L A
Sbjct: 791 KEPAPTTPKKPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSA 841
Query: 346 QSAGTVRSAAP-----PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDE 400
+ +P P K K M+ A + + E DLR+ E
Sbjct: 842 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT----------ERDLRTTPETTT 891
Query: 401 AKAKEEKLEKCGEDDETIPSEY-----RLKPATDKDGKP----------LLPEPEEKPKP 445
A K K E ++T S+ ++ T +D P L P+ K
Sbjct: 892 AAPKMTK-ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 950
Query: 446 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ------ 499
+ +E++++ E+ +KP ++ SKA P P S +
Sbjct: 951 ITTTEIMNK----------PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP 1000
Query: 500 -----SAPPEPATLKGTVPD-DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 553
P P + T+P+ + +A+++ + P P V+ K ED
Sbjct: 1001 RVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ-TPNSKLVEVNPKSEDAG-- 1057
Query: 554 GEKEET-----IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 592
G + ET P + E D D P +P + P +S++
Sbjct: 1058 GAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1101
Score = 50.4 bits (119), Expect = 6e-06
Identities = 157/806 (19%), Positives = 252/806 (31%), Gaps = 94/806 (11%)
Query: 24 HEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSS 83
+E + S P KK A+ S + R+ TK S ++ S
Sbjct: 59 YESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHS 118
Query: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
++ + + S + K K A E +KK + K +++ + K+
Sbjct: 119 VSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK--------LKVKDNKKNRTKKK 170
Query: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK------TKPQDMISAGGE-S 196
PK + +G ++ K ++ Q ++ ST PK P+ + + S
Sbjct: 171 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 230
Query: 197 VAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMD---AALDDLIDT---LGGP 250
++ + + KE + + K S K + DL T L P
Sbjct: 231 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 290
Query: 251 EETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGP--PADSSKP 308
T + TT GP ++ P T K + PK K T P PA ++
Sbjct: 291 --TPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 346
Query: 309 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 368
P +P T KE + K + T + AP K T
Sbjct: 347 SAPT-------------TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT---T 390
Query: 369 MSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPAT 428
+ A T EP + KE K E P+ P T
Sbjct: 391 PKEPAPTTPKKPAPTTPKEPA--PTTPKEPTPTTPK-----------EPAPTTKEPAPTT 437
Query: 429 DKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKE-KPSKPTEKTEESKAAAPAPVS 487
K+ P P +KP P + E ++ + KE P+ P E + +AP
Sbjct: 438 PKEPAPTAP---KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 494
Query: 488 E-AVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAK 546
E A T P P T K P E A + KK A +P KE A
Sbjct: 495 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 547 EEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE----SKEQLPPMSEDFLLDALSEDF 602
++ + P K+ P PK+ + E+L P + + E+
Sbjct: 554 TTTKKPAPTTPKEPAP------TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 607
Query: 603 --SGPQNASSLKFED--AKLAAAISEVVSQTPASTTQAGAPPRDTSQ----SDKDLDDAL 654
+ P+ + E+ A + + PA TT P + + K+
Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 667
Query: 655 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPV 714
K + ++P P P + KE A ++ D P +P
Sbjct: 668 PKGTAPTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725
Query: 715 ----KPPTKKSEDSKKPADDQDPIDAL---SGDLDSCPSTTETSQNTAKDKCKKAASSSK 767
K P + P ++P + P+TT+ +T DK
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785
Query: 768 APKNGGK-----AKDSAKTTEETSKP 788
AP + K A TT ET P
Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETPPP 811
Score = 32.3 bits (72), Expect = 1.8
Identities = 40/241 (16%), Positives = 89/241 (36%), Gaps = 11/241 (4%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P P P+ A + +P+ P E + K+ A + + T
Sbjct: 745 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIP-VSQQMEGPHLPNKKKHK-----KQAV 114
T ++ T + ++++ + ++ P +S + L N K K
Sbjct: 805 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 864
Query: 115 KTEPEK----KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS 170
T+PE K ++T+ + ++ PK E + ++ +++ + + +
Sbjct: 865 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 924
Query: 171 AEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKP 230
+ P + +T T ++ +++ T I KP + K K T + KP KP
Sbjct: 925 QDTTPFKITTLKTTTLAPKVTTTKKTIT-TTEIMNKPEETAKPKDRATNSKATTPKPQKP 983
Query: 231 S 231
+
Sbjct: 984 T 984
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 63.5 bits (153), Expect = 7e-10
Identities = 156/775 (20%), Positives = 253/775 (32%), Gaps = 91/775 (11%)
Query: 37 KPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSG-----ATSKSSSMNPTETKA 91
+P SD K SL ++ + T + K +++ G + ++ S+ T K
Sbjct: 261 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 320
Query: 92 IPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPK 151
+ + ++ P + K T P++ + +T K+ PKE T P ++ K
Sbjct: 321 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTP------KEPASTTPKEPT-PTTI-K 372
Query: 152 QASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKK 211
A T A ++SA P E + P T + + E T +P
Sbjct: 373 SAPTTPKEPA---PTTTKSAPTTPKEPA--PTTTKEPAPTTPKEPAPTTTK---EPAPTT 424
Query: 212 KEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSS 271
+ TP P + P KP+ + + P T + T T P+ P +
Sbjct: 425 TKSAPTTPKEPAPTTPKKPAPTTPKE------------PAPTTPKEPTPTTPKEPAPTTK 472
Query: 272 TYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAG 331
K PK KE PA P P + + + + +P
Sbjct: 473 EPAPTTPKEPAPTAPKKPAPTTPKE-----PA----PTTPKEPAPTTTKEPSPTTPKEPA 523
Query: 332 KKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKD----TMSDQALEALSASLGTRQAE 387
T K T + T + P+E K+ T + A T E
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE 583
Query: 388 PELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEP-----EEK 442
P + KE K+ E T P E P T K P PE EK
Sbjct: 584 PAPT--TPKEPAPTTTKKPAPTTPKEPAPTTPKE--TAPTTPKKLTPTTPEKLAPTTPEK 639
Query: 443 PKPRSESELIDELSEDFDRSECKEKPSKPTEKTEES-KAAAPAPVSEAVCRTSMCSIQSA 501
P P + EL E+ P+ P E + KAAAP E T +
Sbjct: 640 PAPTTPEELAPTTPEE-------PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT 692
Query: 502 PPEPA--TLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEET 559
P EPA T K T P + A + K+ A KP ++ +E +K
Sbjct: 693 PKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751
Query: 560 IPPDYRLEEVKDKDGKPLLPKES-----KEQLPPMSEDFLLDALSEDFSGPQNASSLKFE 614
P K P PKE KE P + L E P + K
Sbjct: 752 TTP---------KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAPTTPKKPA 798
Query: 615 DAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPM 674
+LA ++ + T + P + K+ K P P ++
Sbjct: 799 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 858
Query: 675 EDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKP--PTKKSEDSKKPADDQD 732
++ H+ D++ P ++ P +P PT K+ + KP
Sbjct: 859 TPTTTKEPTTIHKSP----DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 914
Query: 733 PIDALSG-DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNGGKAKDSAKTTEETS 786
D + DL + P TT + K+ ++++ + ++ TT++T+
Sbjct: 915 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTT 969
Score = 62.8 bits (151), Expect = 1e-09
Identities = 190/927 (20%), Positives = 288/927 (31%), Gaps = 171/927 (18%)
Query: 8 PAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKG---------SDEKKAASLGSSQSS 58
P + P ++A + + T SP P +KK ++E + S SS
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169
Query: 59 RTYAGGTASATKVSASSGATS----------KSSSMNPTETKAIP----VSQQMEGPHLP 104
+ + +++ K+ +S + + K + N T+ K P V + G
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 229
Query: 105 NKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNK 164
+ K T+ K S S K++ + P K + + +
Sbjct: 230 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKET 289
Query: 165 KAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDK------------KK 212
++ EK+T K + Q + + +A + + KP K K
Sbjct: 290 TTTNKQTSTDGKEKTTSAK-ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 348
Query: 213 EKKSLTPAVPVESKPDKPSG---KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVS--- 266
E TP P + P +P+ KS + T T +E T E +
Sbjct: 349 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT 408
Query: 267 --DPMSSTYIE---ELGKREVTIPPKYRELLAKKEGITGP------------------PA 303
+P +T E K T P + KK T P PA
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 468
Query: 304 DSSK---PIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAP---- 356
++K P P + +P T KE + K S T + AP
Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 528
Query: 357 --PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLR------------SIKEVDEAK 402
P K T S + T++ P + KE
Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588
Query: 403 AKEEKLEKCGEDDETIPSEYRLKPATDKDGKP-------------LLPEPEEKPKPRSES 449
KE + T P E P T K+ P L P EKP P +
Sbjct: 589 PKEPAPTTTKKPAPTTPKE--PAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646
Query: 450 ELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPA--- 506
EL E+ P +P T KAAAP E T + P EPA
Sbjct: 647 ELAPTTPEE----PTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700
Query: 507 -------TLKGTVP------------DDAVEALADSLGKKEADPEDGKPVMDKVKEKAKE 547
T KGT P A + LA + K+ KP K A
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 760
Query: 548 EDRE--KLGEKEETIPPDYRLEEVKDKDGKPLLPKE-SKEQLPPMSEDFLLDALSE---D 601
+E KE K+ P PK+ + ++L P + S+
Sbjct: 761 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820
Query: 602 FSGPQNASSLKFEDAKLA-AAISEVVSQTPASTTQAGAPPRDTSQS---DKDLDDALDKL 657
+ + A + E A + +TP TT + P T + K D++ +L
Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Query: 658 SDSLGQRQPDPDENKPMEDKV---------KEKAKAEHRDKLGERDDTIPPEYRHLLDDN 708
S + P EN P E V K + +DK ERD PE
Sbjct: 881 S---AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK- 936
Query: 709 GQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKA 768
K T+K+ +SK A + T+ T+Q+T K +++ A
Sbjct: 937 -MTKETATTTEKTTESKITA-------------TTTQVTSTTTQDTTPFKITTLKTTTLA 982
Query: 769 PKNGGKAKDSAKT-----TEETSKPKD 790
PK K T EET+KPKD
Sbjct: 983 PKVTTTKKTITTTEIMNKPEETAKPKD 1009
Score = 52.4 bits (124), Expect = 2e-06
Identities = 135/644 (20%), Positives = 220/644 (34%), Gaps = 101/644 (15%)
Query: 12 PRPRRAAAARRTHEHVSEKTSE--SPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASAT 69
P P +A T + S T++ +P+ P E + KK A + + T A T
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596
Query: 70 KVSASSGATSKSSSMNPTET------KAIPVSQQMEGPHLPNKKKHK--KQAVKTEPEKK 121
+ + + P ET K P + + P P K ++ T PE+
Sbjct: 597 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656
Query: 122 SQST--KLSVVHEKKSQEGKPKEH--TEPK----SLPKQASDTGSNDAH--NKKAVSRSA 171
+ +T + + K + PKE T PK + PK+ + T + K + +
Sbjct: 657 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT 716
Query: 172 EQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKP----GDKKKEKKSLTPAVPVESKP 227
++P+ +T K P+++ + T P G K P P E P
Sbjct: 717 LKEPAP-TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 775
Query: 228 DKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTGPE--VSDPMSSTYIEELGKREVTIP 285
P G + + T P E TT GP SD + T +E T P
Sbjct: 776 TTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP---TTP 831
Query: 286 PKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA 345
+ KK T P P +S+ T PT K + EST L A
Sbjct: 832 KEPAPTTPKKPAPTTPET-------PPPTTSEVSTPTTTKEPTTIHKSPD--ESTPELSA 882
Query: 346 QSAGTVRSAAP-----PQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDE 400
+ +P P K K M+ A + + E DLR+ E
Sbjct: 883 EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTT----------ERDLRTTPETTT 932
Query: 401 AKAKEEKLEKCGEDDETIPSEY-----RLKPATDKDGKP----------LLPEPEEKPKP 445
A K K E ++T S+ ++ T +D P L P+ K
Sbjct: 933 AAPKMTK-ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 991
Query: 446 RSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQ------ 499
+ +E++++ E+ +KP ++ SKA P P S +
Sbjct: 992 ITTTEIMNK----------PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMP 1041
Query: 500 -----SAPPEPATLKGTVPD-DAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKL 553
P P + T+P+ + +A+++ + P P V+ K ED
Sbjct: 1042 RVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQ-TPNSKLVEVNPKSEDAG-- 1098
Query: 554 GEKEET-----IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSED 592
G + ET P + E D D P +P + P +S++
Sbjct: 1099 GAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDE 1142
Score = 50.4 bits (119), Expect = 6e-06
Identities = 157/806 (19%), Positives = 252/806 (31%), Gaps = 94/806 (11%)
Query: 24 HEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSS 83
+E + S P KK A+ S + R+ TK S ++ S
Sbjct: 100 YESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHS 159
Query: 84 MNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEH 143
++ + + S + K K A E +KK + K +++ + K+
Sbjct: 160 VSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKK--------LKVKDNKKNRTKKK 211
Query: 144 TEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPK------TKPQDMISAGGE-S 196
PK + +G ++ K ++ Q ++ ST PK P+ + + S
Sbjct: 212 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 271
Query: 197 VAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMD---AALDDLIDT---LGGP 250
++ + + KE + + K S K + DL T L P
Sbjct: 272 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 331
Query: 251 EETEEENTTYTGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGP--PADSSKP 308
T + TT GP ++ P T K + PK K T P PA ++
Sbjct: 332 --TPKAETTTKGPALTTPKEPT--PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 387
Query: 309 IGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDT 368
P +P T KE + K + T + AP K T
Sbjct: 388 SAPT-------------TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT---T 431
Query: 369 MSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPAT 428
+ A T EP + KE K E P+ P T
Sbjct: 432 PKEPAPTTPKKPAPTTPKEPA--PTTPKEPTPTTPK-----------EPAPTTKEPAPTT 478
Query: 429 DKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKE-KPSKPTEKTEESKAAAPAPVS 487
K+ P P +KP P + E ++ + KE P+ P E + +AP
Sbjct: 479 PKEPAPTAP---KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 535
Query: 488 E-AVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAK 546
E A T P P T K P E A + KK A +P KE A
Sbjct: 536 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP-APTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 547 EEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE----SKEQLPPMSEDFLLDALSEDF 602
++ + P K+ P PK+ + E+L P + + E+
Sbjct: 595 TTTKKPAPTTPKEPAP------TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 648
Query: 603 --SGPQNASSLKFED--AKLAAAISEVVSQTPASTTQAGAPPRDTSQ----SDKDLDDAL 654
+ P+ + E+ A + + PA TT P + + K+
Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 708
Query: 655 DKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPV 714
K + ++P P P + KE A ++ D P +P
Sbjct: 709 PKGTAPTTLKEPAP--TTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766
Query: 715 ----KPPTKKSEDSKKPADDQDPIDAL---SGDLDSCPSTTETSQNTAKDKCKKAASSSK 767
K P + P ++P + P+TT+ +T DK
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826
Query: 768 APKNGGK-----AKDSAKTTEETSKP 788
AP + K A TT ET P
Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETPPP 852
Score = 32.3 bits (72), Expect = 1.8
Identities = 40/241 (16%), Positives = 89/241 (36%), Gaps = 11/241 (4%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
+ +P P P+ A + +P+ P E + K+ A + + T
Sbjct: 786 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 845
Query: 61 YAGGTASATKVSASSGATSKSSSMNPTETKAIP-VSQQMEGPHLPNKKKHK-----KQAV 114
T ++ T + ++++ + ++ P +S + L N K K
Sbjct: 846 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 905
Query: 115 KTEPEK----KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRS 170
T+PE K ++T+ + ++ PK E + ++ +++ + + +
Sbjct: 906 ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 965
Query: 171 AEQQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKP 230
+ P + +T T ++ +++ T I KP + K K T + KP KP
Sbjct: 966 QDTTPFKITTLKTTTLAPKVTTTKKTIT-TTEIMNKPEETAKPKDRATNSKATTPKPQKP 1024
Query: 231 S 231
+
Sbjct: 1025 T 1025
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 63.5 bits (153), Expect = 7e-10
Identities = 165/848 (19%), Positives = 287/848 (33%), Gaps = 119/848 (14%)
Query: 7 KPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTA 66
+ A+P P R V ++ +S S E+ SD + A++ ++Q G +
Sbjct: 448 RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS-SEESDSDREALAAMNAAQVKPL---GKS 503
Query: 67 SATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHK-KQAVKTEPEKKSQS- 124
K +++ G M P A PV GP P+ + K ++ ++ E+ S S
Sbjct: 504 PQVKPASTMG-------MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 556
Query: 125 -----TKLSVVHEKK-SQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEK 178
T ++ EK + K + P P Q + + +K + S + S
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Query: 179 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 238
S + + P M +A + I P + V V ++ + +G + A
Sbjct: 617 SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 676
Query: 239 ALDDLIDTLGGPEETEEENTTY---------TGPEVSDPMSSTYIEELGKREVTIPPK-- 287
+ GG + E++++ TG V+ + + + L + ++P K
Sbjct: 677 GSSPAV--AGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS 734
Query: 288 ----YRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPT---AAGKKTEKEEST 340
+L K G T + K + + + S+ SP + KKT+ + +
Sbjct: 735 LGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANP 794
Query: 341 EVLKAQSA-GTVRS-----AAPPQEKKR---KVEKDTMSDQALEALS------------- 378
+A SA GT+ + A Q K+R KV+ + Q L+
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
Query: 379 ASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPE 438
A+ Q PE D S +E +++ + E L + +T L PA + K P
Sbjct: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914
Query: 439 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 498
P K P + K+ S + + +S APA V+ A
Sbjct: 915 PPGKTGPSAAQA-------------GKQDDSGSSSEESDSDGEAPAAVTSA--------- 952
Query: 499 QSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEE 558
Q P P A A + + + P + + + E + E + +
Sbjct: 953 QVIKP-PLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ 1011
Query: 559 TIPPDYRLEEVKDKDGKP-LLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAK 617
+ P R V P + PK S E +S+ A+ +
Sbjct: 1012 CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKES---SRISDGKKQEGPATQVDSAVGT 1068
Query: 618 LAAAISEVVSQTPASTTQAGAPP----RDTSQSDKDLDDALDKLSDSLGQRQPD--PDEN 671
L A + S T + P + +++ + DD+ D S G + P
Sbjct: 1069 LPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGA 1128
Query: 672 KPMEDKV-----KEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKK 726
K V + + E DD + P L +G P P
Sbjct: 1129 KSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLL---SGYMTPGLTPANSQASKAT 1185
Query: 727 PADDQDPIDALSGDLDSCPSTTET----SQNTAKDKCK-KAASSSKAPKNGGKAKDSAKT 781
P LDS PS + T K + K + A+ +PK GGK S T
Sbjct: 1186 PK------------LDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTT 1233
Query: 782 TEETSKPK 789
+++ KPK
Sbjct: 1234 PQKSRKPK 1241
Score = 62.4 bits (150), Expect = 2e-09
Identities = 170/846 (20%), Positives = 311/846 (36%), Gaps = 108/846 (12%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
PG+ +P + A A +T E+ SES S+ E S+E+ A+ Q
Sbjct: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE--ESSDSEEETPAAKALLQ------- 361
Query: 64 GTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQ 123
A A+ ++ GA S + +P + A P GP + K QA K E + +S
Sbjct: 362 --AKASGKTSQVGAASAPAKESPRK-GAAPAPPGKTGPAVA-----KAQAGKREEDSQSS 413
Query: 124 STKLSVVHEKKSQ---EGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
S + E +Q GK + + K++ G+ A +K +A+ Q ++
Sbjct: 414 SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKP------DKPSGKS 234
+ ++ ++ + E++A + A KP K + K PA + P P GK
Sbjct: 474 DSRSSSEES-DSDREALAAMNAAQVKPLGKSPQVK---PASTMGMGPLGKGAGPVPPGKV 529
Query: 235 GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGK----REVTIPPKYRE 290
G + E + EE++ + EV ++ + LG + + P K
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP- 588
Query: 291 LLAKKEGITGPPADSSKPI----GPDDAIDALSSDFTCGSPTAA-GKKTEKEESTEVLKA 345
+K G + KP+ +++ D+ S+ + TAA K K T+
Sbjct: 589 --PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646
Query: 346 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 405
++ T + P + + + + S ++ P D S +E D + K
Sbjct: 647 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 406 ------EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDF 459
+ + G+ + + +K + + P+LP K P + +++ E ED
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLP---GKTGP-TVTQVKAEKQEDS 762
Query: 460 DRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTV--PDDAV 517
+ SE E E AA+PA V +V +T + +A P+ KGT+ P V
Sbjct: 763 ESSE--------EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA-KGTISAPGKVV 813
Query: 518 EALADSLGKKEAD---------------------PEDGKPVMDKVK-EKAKEEDREKLGE 555
A A + + + P GK V + + EED E
Sbjct: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 873
Query: 556 KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDA--LSEDFSGPQNASSLKF 613
+ ++ L +VK GK + + L P E A +GP A + K
Sbjct: 874 ESDSEEEAETLAQVK-PSGK---THQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
Query: 614 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKP 673
+D+ ++ S+ + PA+ T A D + A + + Q P + +
Sbjct: 930 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 989
Query: 674 MEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPP------------TKKS 721
E + + + + + P R + P P + +
Sbjct: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
Query: 722 EDSKKPADDQDPIDALSGDL--DSCPSTTETSQNT---AKDKCKKAASSSKAPKNGGKAK 776
D KK +D+ G L S ST+ ++ T K K + ++KAP++ ++
Sbjct: 1050 SDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSE 1109
Query: 777 DSAKTT 782
DS+ ++
Sbjct: 1110 DSSDSS 1115
Score = 53.5 bits (127), Expect = 7e-07
Identities = 143/683 (20%), Positives = 226/683 (33%), Gaps = 108/683 (15%)
Query: 173 QQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSG 232
QQ SE + K + + A V+ + S + E++ A ++ P S
Sbjct: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTS-----ESSEEEEEAEAETAKATPRLAST 108
Query: 233 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEEL--GK--REVTIPPKY 288
S + A DL ++ + E E TG + P + + L GK R+ P
Sbjct: 109 NSSVLGA--DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
Query: 289 RELLAKKEGITGPPA--DSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQ 346
L+++ E PA ++KP + A +D + +++ +T+ E V AQ
Sbjct: 167 TTLVSETEEEGSVPAFGAAAKP----GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQ 222
Query: 347 SAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL--GTRQAEPELDLRSIKEVDEAKAK 404
+ S +K + D + +L R +PE + S +E E+
Sbjct: 223 VKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSES--- 279
Query: 405 EEKLEKCGEDDETIPSEYRLK------PATDKDGKPLLPEPEEKPKPRSESELIDELSED 458
E+ G + SE L+ PA GK P P K + + ED
Sbjct: 280 -EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEED 338
Query: 459 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 518
+ S E+ S E+T +KA A S +TS SAP + + KG P
Sbjct: 339 SESSS--EESSDSEEETPAAKALLQAKASG---KTSQVGAASAPAKESPRKGAAP----- 388
Query: 519 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEK---EETIP---------PDYRL 566
A P P + K + +EED + E+ EE P P R
Sbjct: 389 ----------APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 567 EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 626
K+ P++ PP + + SS + D+ A +
Sbjct: 439 ASAPAKES----PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 627 SQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEH 686
+Q P T A +G P K ED E + E
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED--SESSSEES 552
Query: 687 RDKL-GERDDTIPPEYRHLLDDNGQDKPVKPPTK-----------------------KSE 722
D GE + P L + Q KP P K SE
Sbjct: 553 SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612
Query: 723 DSKKPADDQDPIDALSG----------DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNG 772
+S AD ++ A++ +CP T T TA K ++AP+
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT---TASAKVAPVRVGTQAPRKA 669
Query: 773 GKAKDSAKTTEE----TSKPKDD 791
G A A ++ T +P +D
Sbjct: 670 GTATSPAGSSPAVAGGTQRPAED 692
Score = 48.5 bits (114), Expect = 2e-05
Identities = 84/404 (20%), Positives = 149/404 (36%), Gaps = 61/404 (15%)
Query: 2 SQPGQKPAASPRPR--RAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSR 59
S G PA SP+ +A + + + ++ P S++ +S GS +
Sbjct: 1064 SAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGE 1123
Query: 60 TYAGGTASATKVSASSGATS---KSSSMNPTETKAIPVSQQM-EGPHLPNKKKHKKQAVK 115
G ++ T V + T + ++ +E + SQ + G P QA K
Sbjct: 1124 GPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1183
Query: 116 TEPEKKSQSTKLSVVHEKKS----QEGKPKEHT---EPKSLPKQASDTGSNDAHNKKAVS 168
P+ S + S + K QE KP++ PK+ K+A+ +G+ ++K
Sbjct: 1184 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAA-SGTTPQKSRKPKK 1242
Query: 169 RSAEQQPSEKSTE------------PKTKPQ----------DMISAGGESVAGITAISGK 206
+ Q S + + P + Q +++ + V T S +
Sbjct: 1243 GAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSR 1302
Query: 207 PG--DKKKEKKSLTPAV--PVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 262
G +K++ PA P K K G +A++ PE+T +TT G
Sbjct: 1303 KGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS--------PEKT---STTSKG 1351
Query: 263 PEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDF 322
D S E+ GK L + P + K +G + D +
Sbjct: 1352 KAKRDKASGDVKEKKGKGS----------LGSQGAKDEPEEELQKGMGTVEGGDQSNPKS 1401
Query: 323 TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEK 366
+ +K +KE+ + KA+ A T S +P Q+KK+K +K
Sbjct: 1402 KKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1445
Score = 42.4 bits (98), Expect = 0.002
Identities = 161/854 (18%), Positives = 295/854 (34%), Gaps = 99/854 (11%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
M+ KPA P+ A ++T+ S K + P + G + + K + + SS
Sbjct: 627 MTAAQAKPALKI-PQTKACPKKTNTTASAKVA--PVRVGTQ--APRKAGTATSPAGSSPA 681
Query: 61 YAGGTASATKVSASSGATSKSSSMN----------------PTETKAIPVSQQM---EGP 101
AGGT + S+SS + + ++PV + P
Sbjct: 682 VAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 102 HLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKS----QEGKPKEHTEPKSLPKQA---S 154
LP K VK E ++ S+S++ E+ + Q + T+ K+ P A S
Sbjct: 742 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 155 DTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK-PQDMISAGGESVAGITAISGKPGDKKKE 213
G+ A K + + +Q S +P + PQ+ T ++ P
Sbjct: 802 AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNS-----------TVLARGPASVPSV 850
Query: 214 KKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGG--PEETEEENTTYTGPEVSDPMSS 271
K++ A ++ P++ SG S ++ ++ +TL P + P P
Sbjct: 851 GKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG 910
Query: 272 TYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPT--A 329
GK T P + A K+ +G ++ S G +A A++S P
Sbjct: 911 AAPTPPGK---TGPSAAQ---AGKQDDSGSSSEESDSDG--EAPAAVTSAQVIKPPLIFV 962
Query: 330 AGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA---LSASLGTR-- 384
++ + +AQ+A T R A + R ++ + + A L+ + T
Sbjct: 963 DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVV 1022
Query: 385 ---QAEPELDLR-------SIKE---VDEAKAKEEKLEKCGEDDETIPSEYRLKPA---- 427
A P + + S KE + + K +E + T+P+ +
Sbjct: 1023 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAK 1082
Query: 428 -TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPV 486
T+K KP LPE ++ K S+ ++ S+ SE + + + P+
Sbjct: 1083 GTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRT 1142
Query: 487 SEAVCRTSMCSIQS--APPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEK 544
V T+ S + P + L G + A +S K D P +
Sbjct: 1143 ETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPA--NSQASKATPKLDSSPSVSSTLAA 1200
Query: 545 AKEEDREKLGEKEET---IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDA-LSE 600
+ D ++ + ++ + P +E K K P + L + +++
Sbjct: 1201 KDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQ 1260
Query: 601 DFSG---PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDA---- 653
G P N + ++ K+ + E + TT+ + S+ K D
Sbjct: 1261 CLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAAR 1320
Query: 654 --LDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQD 711
K LG + P + K KA+ RDK D + + L G
Sbjct: 1321 TPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAK-RDKAS--GDVKEKKGKGSLGSQGAK 1377
Query: 712 KPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSKAPKN 771
+ +K + + D +P + S + + K K KKA++ +
Sbjct: 1378 DEPEEELQKGMGTVEGGDQSNP-KSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPS 1436
Query: 772 GGKAKDSAKTTEET 785
K K KT E+T
Sbjct: 1437 QKKKKKKKKTAEQT 1450
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 63.5 bits (153), Expect = 7e-10
Identities = 167/855 (19%), Positives = 291/855 (34%), Gaps = 134/855 (15%)
Query: 7 KPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTA 66
+ A+P P R V ++ +S S E+ SD + A++ ++Q G +
Sbjct: 448 RKGAAPAPPRKTGPAAAQVQVGKQEEDSRSS-SEESDSDREALAAMNAAQVKPL---GKS 503
Query: 67 SATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHK-KQAVKTEPEKKSQS- 124
K +++ G M P A PV GP P+ + K ++ ++ E+ S S
Sbjct: 504 PQVKPASTMG-------MGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 556
Query: 125 -----TKLSVVHEKK-SQEGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEK 178
T ++ EK + K + P P Q + + +K + S + S
Sbjct: 557 DGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSD 616
Query: 179 STEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDA 238
S + + P M +A + I P + V V ++ + +G + A
Sbjct: 617 SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPA 676
Query: 239 ALDDLIDTLGGPEETEEENTTY---------TGPEVSDPMSSTYIEELGKREVTIPPK-- 287
+ GG + E++++ TG V+ + + + L + ++P K
Sbjct: 677 GSSPAV--AGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS 734
Query: 288 ----YRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPT---AAGKKTEKEEST 340
+L K G T + K + + + S+ SP + KKT+ + +
Sbjct: 735 LGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANP 794
Query: 341 EVLKAQSA-GTVRS-----AAPPQEKKR---KVEKDTMSDQALEALS------------- 378
+A SA GT+ + A Q K+R KV+ + Q L+
Sbjct: 795 AAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAV 854
Query: 379 ASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGKPLLPE 438
A+ Q PE D S +E +++ + E L + +T L PA + K P
Sbjct: 855 ATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT 914
Query: 439 PEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSI 498
P K P + K+ S + + +S APA V+ A
Sbjct: 915 PPGKTGPSAAQA-------------GKQDDSGSSSEESDSDGEAPAAVTSA--------- 952
Query: 499 QSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEKEE 558
Q P P A A + + + P + + + E + E + +
Sbjct: 953 QVIKP-PLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ 1011
Query: 559 TIPPDYRLEEVKDKDGKP-LLPKES-----------------KEQLPPMSEDFLLDALSE 600
+ P R V P + PK S K++ P D + L
Sbjct: 1012 CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPA 1071
Query: 601 DFSGPQNASSLKFEDAKLAAA-ISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSD 659
+ PQ+ S KL + EV T A + + S S + D + +
Sbjct: 1072 --TSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAK 1129
Query: 660 SLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPPTK 719
S P P + + ++ ++ DD + P L +G P P
Sbjct: 1130 SAHTLGPTPSRTETLVEETAAESS---------EDDVVAPSQSLL---SGYMTPGLTPAN 1177
Query: 720 KSEDSKKPADDQDPIDALSGDLDSCPSTTET----SQNTAKDKCK-KAASSSKAPKNGGK 774
P LDS PS + T K + K + A+ +PK GGK
Sbjct: 1178 SQASKATPK------------LDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGK 1225
Query: 775 AKDSAKTTEETSKPK 789
S T +++ KPK
Sbjct: 1226 EAASGTTPQKSRKPK 1240
Score = 62.4 bits (150), Expect = 2e-09
Identities = 170/846 (20%), Positives = 311/846 (36%), Gaps = 108/846 (12%)
Query: 4 PGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAG 63
PG+ +P + A A +T E+ SES S+ E S+E+ A+ Q
Sbjct: 311 PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSE--ESSDSEEETPAAKALLQ------- 361
Query: 64 GTASATKVSASSGATSKSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQ 123
A A+ ++ GA S + +P + A P GP + K QA K E + +S
Sbjct: 362 --AKASGKTSQVGAASAPAKESPRK-GAAPAPPGKTGPAVA-----KAQAGKREEDSQSS 413
Query: 124 STKLSVVHEKKSQ---EGKPKEHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKST 180
S + E +Q GK + + K++ G+ A +K +A+ Q ++
Sbjct: 414 SEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEE 473
Query: 181 EPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKP------DKPSGKS 234
+ ++ ++ + E++A + A KP K + K PA + P P GK
Sbjct: 474 DSRSSSEES-DSDREALAAMNAAQVKPLGKSPQVK---PASTMGMGPLGKGAGPVPPGKV 529
Query: 235 GMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEELGK----REVTIPPKYRE 290
G + E + EE++ + EV ++ + LG + + P K
Sbjct: 530 GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP- 588
Query: 291 LLAKKEGITGPPADSSKPI----GPDDAIDALSSDFTCGSPTAA-GKKTEKEESTEVLKA 345
+K G + KP+ +++ D+ S+ + TAA K K T+
Sbjct: 589 --PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK 646
Query: 346 QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKE 405
++ T + P + + + + S ++ P D S +E D + K
Sbjct: 647 KTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKT 706
Query: 406 ------EKLEKCGEDDETIPSEYRLKPATDKDGKPLLPEPEEKPKPRSESELIDELSEDF 459
+ + G+ + + +K + + P+LP K P + +++ E ED
Sbjct: 707 GLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLP---GKTGP-TVTQVKAEKQEDS 762
Query: 460 DRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTV--PDDAV 517
+ SE E E AA+PA V +V +T + +A P+ KGT+ P V
Sbjct: 763 ESSE--------EESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSA-KGTISAPGKVV 813
Query: 518 EALADSLGKKEAD---------------------PEDGKPVMDKVK-EKAKEEDREKLGE 555
A A + + + P GK V + + EED E
Sbjct: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 873
Query: 556 KEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDA--LSEDFSGPQNASSLKF 613
+ ++ L +VK GK + + L P E A +GP A + K
Sbjct: 874 ESDSEEEAETLAQVK-PSGK---THQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQ 929
Query: 614 EDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKP 673
+D+ ++ S+ + PA+ T A D + A + + Q P + +
Sbjct: 930 DDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARA 989
Query: 674 MEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDKPVKPP------------TKKS 721
E + + + + + P R + P P + +
Sbjct: 990 SESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRI 1049
Query: 722 EDSKKPADDQDPIDALSGDL--DSCPSTTETSQNT---AKDKCKKAASSSKAPKNGGKAK 776
D KK +D+ G L S ST+ ++ T K K + ++KAP++ ++
Sbjct: 1050 SDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSE 1109
Query: 777 DSAKTT 782
DS+ ++
Sbjct: 1110 DSSDSS 1115
Score = 53.5 bits (127), Expect = 7e-07
Identities = 143/683 (20%), Positives = 226/683 (33%), Gaps = 108/683 (15%)
Query: 173 QQPSEKSTEPKTKPQDMISAGGESVAGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSG 232
QQ SE + K + + A V+ + S + E++ A ++ P S
Sbjct: 54 QQTSELGRKRKAEEDAALQAKKTRVSDPISTS-----ESSEEEEEAEAETAKATPRLAST 108
Query: 233 KSGMDAALDDLIDTLGGPEETEEENTTYTGPEVSDPMSSTYIEEL--GK--REVTIPPKY 288
S + A DL ++ + E E TG + P + + L GK R+ P
Sbjct: 109 NSSVLGA--DLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSAN 166
Query: 289 RELLAKKEGITGPPA--DSSKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQ 346
L+++ E PA ++KP + A +D + +++ +T+ E V AQ
Sbjct: 167 TTLVSETEEEGSVPAFGAAAKP----GMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQ 222
Query: 347 SAGTVRSAAPPQEKKRKVEKDTMSDQALEALSASL--GTRQAEPELDLRSIKEVDEAKAK 404
+ S +K + D + +L R +PE + S +E E+
Sbjct: 223 VKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSES--- 279
Query: 405 EEKLEKCGEDDETIPSEYRLK------PATDKDGKPLLPEPEEKPKPRSESELIDELSED 458
E+ G + SE L+ PA GK P P K + + ED
Sbjct: 280 -EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEED 338
Query: 459 FDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVE 518
+ S E+ S E+T +KA A S +TS SAP + + KG P
Sbjct: 339 SESSS--EESSDSEEETPAAKALLQAKASG---KTSQVGAASAPAKESPRKGAAP----- 388
Query: 519 ALADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLGEK---EETIP---------PDYRL 566
A P P + K + +EED + E+ EE P P R
Sbjct: 389 ----------APPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRA 438
Query: 567 EEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVV 626
K+ P++ PP + + SS + D+ A +
Sbjct: 439 ASAPAKES----PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNA 494
Query: 627 SQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEH 686
+Q P T A +G P K ED E + E
Sbjct: 495 AQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEED--SESSSEES 552
Query: 687 RDKL-GERDDTIPPEYRHLLDDNGQDKPVKPPTK-----------------------KSE 722
D GE + P L + Q KP P K SE
Sbjct: 553 SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 612
Query: 723 DSKKPADDQDPIDALSG----------DLDSCPSTTETSQNTAKDKCKKAASSSKAPKNG 772
+S AD ++ A++ +CP T T TA K ++AP+
Sbjct: 613 ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNT---TASAKVAPVRVGTQAPRKA 669
Query: 773 GKAKDSAKTTEE----TSKPKDD 791
G A A ++ T +P +D
Sbjct: 670 GTATSPAGSSPAVAGGTQRPAED 692
Score = 46.6 bits (109), Expect = 9e-05
Identities = 89/404 (22%), Positives = 151/404 (37%), Gaps = 62/404 (15%)
Query: 2 SQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTY 61
S G PA SP+ + A+ T++ K E + SD+ + +S SS S
Sbjct: 1064 SAVGTLPATSPQST-SVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDG 1122
Query: 62 AG--GTASATKVSASSGATS---KSSSMNPTETKAIPVSQQM-EGPHLPNKKKHKKQAVK 115
G G SA + + T + ++ +E + SQ + G P QA K
Sbjct: 1123 EGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASK 1182
Query: 116 TEPEKKSQSTKLSVVHEKKS----QEGKPKEHT---EPKSLPKQASDTGSNDAHNKKAVS 168
P+ S + S + K QE KP++ PK+ K+A+ +G+ ++K
Sbjct: 1183 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAA-SGTTPQKSRKPKK 1241
Query: 169 RSAEQQPSEKSTE------------PKTKPQ----------DMISAGGESVAGITAISGK 206
+ Q S + + P + Q +++ + V T S +
Sbjct: 1242 GAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSR 1301
Query: 207 PG--DKKKEKKSLTPAV--PVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENTTYTG 262
G +K++ PA P K K G +A++ PE+T +TT G
Sbjct: 1302 KGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS--------PEKT---STTSKG 1350
Query: 263 PEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDF 322
D S E+ GK L + P + K +G + D +
Sbjct: 1351 KAKRDKASGDVKEKKGKGS----------LGSQGAKDEPEEELQKGMGTVEGGDQSNPKS 1400
Query: 323 TCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEK 366
+ +K +KE+ + KA+ A T S +P Q+KK+K +K
Sbjct: 1401 KKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKK 1444
Score = 45.1 bits (105), Expect = 3e-04
Identities = 163/858 (18%), Positives = 297/858 (34%), Gaps = 108/858 (12%)
Query: 1 MSQPGQKPAASPRPRRAAAARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRT 60
M+ KPA P+ A ++T+ S K + P + G + + K + + SS
Sbjct: 627 MTAAQAKPALKI-PQTKACPKKTNTTASAKVA--PVRVGTQ--APRKAGTATSPAGSSPA 681
Query: 61 YAGGTASATKVSASSGATSKSSSMN----------------PTETKAIPVSQQM---EGP 101
AGGT + S+SS + + ++PV + P
Sbjct: 682 VAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 741
Query: 102 HLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKS----QEGKPKEHTEPKSLPKQA---S 154
LP K VK E ++ S+S++ E+ + Q + T+ K+ P A S
Sbjct: 742 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 801
Query: 155 DTGSNDAHNKKAVSRSAEQQPSEKSTEPKTK-PQDMISAGGESVAGITAISGKPGDKKKE 213
G+ A K + + +Q S +P + PQ+ T ++ P
Sbjct: 802 AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNS-----------TVLARGPASVPSV 850
Query: 214 KKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGG--PEETEEENTTYTGPEVSDPMSS 271
K++ A ++ P++ SG S ++ ++ +TL P + P P
Sbjct: 851 GKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG 910
Query: 272 TYIEELGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAIDALSSDFTCGSPT--A 329
GK T P + A K+ +G ++ S G +A A++S P
Sbjct: 911 AAPTPPGK---TGPSAAQ---AGKQDDSGSSSEESDSDG--EAPAAVTSAQVIKPPLIFV 962
Query: 330 AGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMSDQALEA---LSASLGTR-- 384
++ + +AQ+A T R A + R ++ + + A L+ + T
Sbjct: 963 DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVV 1022
Query: 385 ---QAEPELDLR-------SIKE---VDEAKAKEEKLEKCGEDDETIPSEYRLKPA---- 427
A P + + S KE + + K +E + T+P+ +
Sbjct: 1023 TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAK 1082
Query: 428 -TDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAP- 485
T+K KP LPE ++ K S D+ + D S E+ + + + + P P
Sbjct: 1083 GTNKLRKPKLPEVQQATKAPESS---DDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPS 1139
Query: 486 -----VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDK 540
V E +S + + P + L G + A +S K D P +
Sbjct: 1140 RTETLVEETAAESSEDDVVA--PSQSLLSGYMTPGLTPA--NSQASKATPKLDSSPSVSS 1195
Query: 541 VKEKAKEEDREKLGEKEET---IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDA 597
+ D ++ + ++ + P +E K K P + L +
Sbjct: 1196 TLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQS 1255
Query: 598 -LSEDFSG---PQNASSLKFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDA 653
+++ G P N + ++ K+ + E + TT+ + S+ K D
Sbjct: 1256 NITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQ 1315
Query: 654 ------LDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEYRHLLDD 707
K LG + P + K KA+ RDK D + + L
Sbjct: 1316 PAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAK-RDKAS--GDVKEKKGKGSLGS 1372
Query: 708 NGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTETSQNTAKDKCKKAASSSK 767
G + +K + + D +P + S + + K K KKA++
Sbjct: 1373 QGAKDEPEEELQKGMGTVEGGDQSNP-KSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1431
Query: 768 APKNGGKAKDSAKTTEET 785
+ K K KT E+T
Sbjct: 1432 ESPSQKKKKKKKKTAEQT 1449
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 63.2 bits (152), Expect = 9e-10
Identities = 131/612 (21%), Positives = 228/612 (37%), Gaps = 94/612 (15%)
Query: 88 ETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPK------ 141
ET A+ ++ E KK K Q K + + S +L K + KPK
Sbjct: 77 ETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSG 136
Query: 142 --EHTEPKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESV-A 198
+ + LPK+A G NKK ++ S+K K + I++ GES
Sbjct: 137 SDDDDDFNKLPKKAK--GKAQKSNKKWDGSEEDEDNSKK-----IKERSRINSSGESGDE 189
Query: 199 GITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLGGPEETEEENT 258
+ + G KK +K P + ++ D S K I T+ + ++E
Sbjct: 190 SDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFK----------IKTVAQKKAEKKERE 239
Query: 259 TYTGPEVSDPMSSTYIEE---LGKREVTIPPKYRELLAKKEGITGPPADSSKPIGPDDAI 315
E + +E GK++ + K +E K E T SK I
Sbjct: 240 RKKRDEEKAKLRKLKEKEELETGKKDQS---KQKESQRKFEEETV----KSKVTVDTGVI 292
Query: 316 DALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVEKDTMS--DQA 373
A S+ +PTAA E ++ + K + +EKK+ K T+ +A
Sbjct: 293 PA--SEEKAETPTAAEDDNEGDKKKKDKKKKKG---EKEEKEKEKKKGPSKATVKAMQEA 347
Query: 374 LEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLKPATDKDGK 433
L L ++ E E ++ ++E++ + +EE+LE+ + + E K K+GK
Sbjct: 348 LAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ-EKRERKKQKEKERKERLKKEGK 406
Query: 434 PLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT 493
LL + + + + R+E+ L ++ + P K ++ + P +
Sbjct: 407 -LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSE 465
Query: 494 SM--CSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKAKEEDRE 551
SM C+ AVE + + +KE P +P ++ E A +D E
Sbjct: 466 SMELCA------------------AVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWE 507
Query: 552 KLGEKEETIPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDFLLDALSEDFSGPQNASSL 611
+ EET + ++ K+ P+E +E+ ED + E+ G S
Sbjct: 508 AMASDEETEKVEGNKVHIEVKEN----PEEEEEEEEEEEEDEESEE-EEEEEGESEGSEG 562
Query: 612 KFEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQSDKDLDDALDKLSDSLGQRQPDPDEN 671
ED K++ D S K LD K S + D D++
Sbjct: 563 DEEDEKVS----------------------DEKDSGKTLDKKPSKEMSS--DSEYDSDDD 598
Query: 672 KPMEDKVKEKAK 683
+ E++ +KAK
Sbjct: 599 RTKEERAYDKAK 610
Score = 58.2 bits (139), Expect = 3e-08
Identities = 123/651 (18%), Positives = 238/651 (36%), Gaps = 110/651 (16%)
Query: 132 EKKSQEGKPKEHTEPKSLPKQASDTGS--NDAHNKKAVSRSAEQQPSEKSTEPKTKPQDM 189
+K E K+ + +L + G+ K + E++ + + K +
Sbjct: 5 QKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE 64
Query: 190 ISAGGESV-AGITAISGKPGDKKKEKKSLTPAVPVESKPDKPSGKSGMDAALDDLIDTLG 248
+S + + A ++ KP + +E+ + SK K G+ G + DD
Sbjct: 65 LSLEAQGIKADRETVAVKPTENNEEEFT--------SKDKKKKGQKGKKQSFDD-----N 111
Query: 249 GPEETEEENTTY---TGPEVSDPMSSTYIEELGKREVTIPPKYRELLAKKEGITGPPADS 305
EE E++++ P+V S ++ K K ++ K +G + D+
Sbjct: 112 DSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDG-SEEDEDN 170
Query: 306 SKPIGPDDAIDALSSDFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSAAPPQEKKRKVE 365
SK I I++ +K +K+ K + + S + K++
Sbjct: 171 SKKIKERSRINSSGESGDESDEFLQSRKGQKKNQ----KNKPGPNIESGNEDDDASFKIK 226
Query: 366 KDTMSDQALEALSASLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCGEDDETIPSEYRLK 425
T++ + E R E + LR +KE +E + ++ K E E
Sbjct: 227 --TVAQKKAEKKERERKKRDEE-KAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKS 283
Query: 426 PATDKDGKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSKPTEKTEESKAAAPAP 485
T G ++P EEK + + +E D+ D + + K+K + EK +E K
Sbjct: 284 KVTVDTG--VIPASEEKAETPTAAE--DDNEGDKKKKDKKKKKGEKEEKEKEKKKG---- 335
Query: 486 VSEAVCRTSMCSIQSAPPEPATLKGTVPDDAVEALADSLGKKEADPEDGKPVMDKVKEKA 545
P AT+K +A+ L + +++ + E+ +++++ K
Sbjct: 336 -----------------PSKATVKAM--QEALAKLKEEEERQKREEEERIKRLEELEAKR 376
Query: 546 KEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLPKE----------------------SK 583
KEE+R + ++E + +E K+GK L + SK
Sbjct: 377 KEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSK 436
Query: 584 EQLP---PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAAAISEVVSQTPAS--TTQAGA 638
+ LP P+ ED + + + + S++ L AA+ + P T
Sbjct: 437 DSLPKKRPIYEDKKRKKIPQQLESKEVSESME-----LCAAVEVMEQGVPEKEETPPPVE 491
Query: 639 PPRDTSQSDKDLDDALDKLSDSLGQR---------------QPDPDENKPMEDKVKEKAK 683
P + D LDD SD ++ + + +E + ED+ E+ +
Sbjct: 492 PEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEE 551
Query: 684 AEHRDKLG----ERDDTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKPADD 730
E + G E D+ + E D+G+ KP + S DS+ +DD
Sbjct: 552 EEEGESEGSEGDEEDEKVSDE-----KDSGKTLDKKPSKEMSSDSEYDSDD 597
Score = 54.7 bits (130), Expect = 3e-07
Identities = 100/489 (20%), Positives = 182/489 (37%), Gaps = 60/489 (12%)
Query: 38 PGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATSKSSSMNPTETKAIPVSQQ 97
P + KG +K S+ + +++++S + +S + +
Sbjct: 147 PKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKN 206
Query: 98 MEGPHLP--NKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTEPKSLP---KQ 152
GP++ N+ +KT +KK+ EKK +E K ++ + K K+
Sbjct: 207 KPGPNIESGNEDDDASFKIKTVAQKKA---------EKKERERKKRDEEKAKLRKLKEKE 257
Query: 153 ASDTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQDMISAGGESVAGITAISG-KPGDKK 211
+TG D +K R E++ + T +I A E TA GDKK
Sbjct: 258 ELETGKKDQSKQKESQRKFEEETVKSKVTVDT---GVIPASEEKAETPTAAEDDNEGDKK 314
Query: 212 KEKKSLTPAVPVESKPDKPSGKSGMDA-ALDDLIDTLGGPEETEEENTTYTGPEVSDPMS 270
K+ K E + +K G S A+ + + L EE ++ + + +
Sbjct: 315 KKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEA 374
Query: 271 STYIEELGKREVTIPPKYRE------------LLAKKEGITGPPADSSKPIGPDDAIDAL 318
EE ++E K +E LL K + A+++ + ++
Sbjct: 375 KRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVP 434
Query: 319 SSD-FTCGSPTAAGKKTEK----------EESTEVLKA-----QSAGTVRSAAPPQEKKR 362
S D P KK +K ES E+ A Q PP E +
Sbjct: 435 SKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEE 494
Query: 363 KVEKDTMSDQALEALSASLGTRQAE-----------PELDLRSIKEVDEAKAKEEKLEKC 411
+ + + EA+++ T + E PE + +E +E + EE+ E+
Sbjct: 495 EEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEE 554
Query: 412 GEDDETIPSEYRLKPATDKD-GKPLLPEPEEKPKPRSESELIDELSEDFDRSECKEKPSK 470
GE + + E K + +KD GK L +P ++ SE + D+ +++ +R+ K K
Sbjct: 555 GESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE-ERAYDKAKRRI 613
Query: 471 PTEKTEESK 479
+ E SK
Sbjct: 614 EKRRLEHSK 622
Score = 41.2 bits (95), Expect = 0.004
Identities = 49/211 (23%), Positives = 79/211 (37%), Gaps = 28/211 (13%)
Query: 20 ARRTHEHVSEKTSESPSKPGEKKGSDEKKAASLGSSQSSRTYAGGTASATKVSASSGATS 79
A+R E E+ K EK+ + K ++S R + K+ + G
Sbjct: 374 AKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEV 433
Query: 80 KSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQAVKTEPEKKSQSTKLSVVHEKKSQEGK 139
S P K P+ + KK KK + E ++ S+S +L E Q
Sbjct: 434 PSKDSLP---KKRPIYED---------KKRKKIPQQLESKEVSESMELCAAVEVMEQGVP 481
Query: 140 PKEHTEPKSLPKQASDTG----------SNDAHNKKA----VSRSAEQQPSEKSTEPKTK 185
KE T P P++ DT ++D +K V ++ P E+ E + +
Sbjct: 482 EKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEE 541
Query: 186 PQDMISAGGESVAGITAISGKPGDKKKEKKS 216
+D S E G + G GD++ EK S
Sbjct: 542 EEDEESEEEEEEEGES--EGSEGDEEDEKVS 570
Score = 37.0 bits (84), Expect = 0.071
Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 26/168 (15%)
Query: 642 DTSQSDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERDDTIPPEY 701
D+++ D DLD ++ + ++ +P ++K + K K+K + D L E ++ + E
Sbjct: 11 DSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEE-LSLEA 69
Query: 702 RHL-----------LDDNGQDKPVKPPTKKSEDSKKPADDQDPIDALSGDLDSCPSTTET 750
+ + ++N ++ K KK + KK + D + + L D DS
Sbjct: 70 QGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELE-DKDS------K 122
Query: 751 SQNTAKDKCKKAASS------SKAPKNG-GKAKDSAKTTEETSKPKDD 791
S+ TAK K + + S +K PK GKA+ S K + + + +D+
Sbjct: 123 SKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDN 170
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.299 0.120 0.322
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,087,270
Number of Sequences: 37866
Number of extensions: 1996400
Number of successful extensions: 15442
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 1123
Number of HSP's that attempted gapping in prelim test: 9601
Number of HSP's gapped (non-prelim): 5021
length of query: 791
length of database: 18,247,518
effective HSP length: 110
effective length of query: 681
effective length of database: 14,082,258
effective search space: 9590017698
effective search space used: 9590017698
T: 11
A: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.