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Search of human proteins with 8923396
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923396 HAUS augmin-like complex, subunit 4 [Homo sapiens]
(363 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923396 HAUS augmin-like complex, subunit 4 [Homo sapiens] 716 0.0
gi|221139761 zinc finger protein 853 [Homo sapiens] 44 2e-04
gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo sapi... 42 0.001
gi|73623035 sperm associated antigen 5 [Homo sapiens] 41 0.001
gi|226493512 coiled-coil domain containing 81 isoform 1 [Homo sa... 41 0.002
gi|226528772 coiled-coil domain containing 81 isoform 2 [Homo sa... 41 0.002
gi|55770834 centromere protein F [Homo sapiens] 41 0.002
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 40 0.002
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 39 0.006
gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens] 39 0.006
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 39 0.007
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 38 0.012
gi|28269672 serologically defined colon cancer antigen 8 [Homo s... 38 0.016
gi|32698688 citron [Homo sapiens] 37 0.021
gi|5803145 ralA binding protein 1 [Homo sapiens] 36 0.047
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 36 0.062
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens] 35 0.080
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens] 35 0.080
gi|154354985 hook homolog 2 isoform 1 [Homo sapiens] 35 0.080
gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 35 0.10
gi|223029422 SKI-like isoform 3 [Homo sapiens] 35 0.14
gi|223029420 SKI-like isoform 2 [Homo sapiens] 35 0.14
gi|223029418 SKI-like isoform 1 [Homo sapiens] 35 0.14
gi|62243374 MAD1-like 1 protein [Homo sapiens] 35 0.14
gi|62243369 MAD1-like 1 protein [Homo sapiens] 35 0.14
gi|62243332 MAD1-like 1 protein [Homo sapiens] 35 0.14
gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isof... 35 0.14
gi|45505178 cancer antigen 1 [Homo sapiens] 34 0.18
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 34 0.18
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 34 0.18
>gi|8923396 HAUS augmin-like complex, subunit 4 [Homo sapiens]
Length = 363
Score = 716 bits (1847), Expect = 0.0
Identities = 363/363 (100%), Positives = 363/363 (100%)
Query: 1 MASGDFCSPGEGMEILQQVCSKQLPPCNLSKEDLLQNPYFSKLLLNLSQHVDESGLSLTL 60
MASGDFCSPGEGMEILQQVCSKQLPPCNLSKEDLLQNPYFSKLLLNLSQHVDESGLSLTL
Sbjct: 1 MASGDFCSPGEGMEILQQVCSKQLPPCNLSKEDLLQNPYFSKLLLNLSQHVDESGLSLTL 60
Query: 61 AKEQAQAWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVTSEDKKFHETLEQRLL 120
AKEQAQAWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVTSEDKKFHETLEQRLL
Sbjct: 61 AKEQAQAWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVTSEDKKFHETLEQRLL 120
Query: 121 VTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRARLQQEVEEQLKKKCFTLL 180
VTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRARLQQEVEEQLKKKCFTLL
Sbjct: 121 VTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRARLQQEVEEQLKKKCFTLL 180
Query: 181 CYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLR 240
CYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLR
Sbjct: 181 CYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLR 240
Query: 241 CLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHR 300
CLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHR
Sbjct: 241 CLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHR 300
Query: 301 LIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDRLVKEYTVLKQATENKRWALQEFSK 360
LIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDRLVKEYTVLKQATENKRWALQEFSK
Sbjct: 301 LIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDRLVKEYTVLKQATENKRWALQEFSK 360
Query: 361 VYR 363
VYR
Sbjct: 361 VYR 363
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 44.3 bits (103), Expect = 2e-04
Identities = 56/253 (22%), Positives = 112/253 (44%), Gaps = 21/253 (8%)
Query: 112 HETLEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRARLQQEVEEQ 171
H+ L+ L + + L P Q +E L ++ L + + + +LQQ+V+EQ
Sbjct: 143 HQELKPELQLMHQQQQLQPQQVQE-QQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQ 201
Query: 172 LKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQQKEQMLLLEKKS 231
LL E ++ ++ + E L +Q Q Q + QQ++Q+LLL+++
Sbjct: 202 ------QLL-------QQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQG 248
Query: 232 AAYSQVL-LRCLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSDT 290
Q+L + L Q+LL++ + + Q +L + L+ + +L+ + E+L+
Sbjct: 249 QLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQ 308
Query: 291 YTVEKVEVHRLIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFD------RLVKEYTVL 344
+ E + L EQ++E RQ L + L + + +L +E L
Sbjct: 309 PPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQL 368
Query: 345 KQATENKRWALQE 357
+Q E ++ L++
Sbjct: 369 EQQLEQQQQQLEQ 381
>gi|44917604 SLIT-ROBO Rho GTPase activating protein 1 [Homo
sapiens]
Length = 1085
Score = 41.6 bits (96), Expect = 0.001
Identities = 41/189 (21%), Positives = 85/189 (44%), Gaps = 29/189 (15%)
Query: 144 KADLLELMPLTEDFVWMRARLQQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLA 203
+A L+E E MR +L Q++++ +KK A+ ET + + KLA
Sbjct: 25 RAQLVEQQKCLEQQTEMRVQLLQDLQDFFRKK-------------AEIETEYSRNLEKLA 71
Query: 204 EVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSELDRI 263
E + + + +D + +K+Q LL S LL L ++R ++H + L+ +
Sbjct: 72 ERFMAKTRSTKDHQQYKKDQNLL----SPVNCWYLL--LNQVRRESKDHATLSDIYLNNV 125
Query: 264 NAQYLEV---------KCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQE 314
+++++ K + +L + +K+L++ YTV K H + + L+E
Sbjct: 126 IMRFMQISEDSTRMFKKSKEIAFQLHEDLMKVLNELYTVMKT-YHMYHAESISAESKLKE 184
Query: 315 QDMENSRQV 323
+ + +Q+
Sbjct: 185 AEKQEEKQI 193
>gi|73623035 sperm associated antigen 5 [Homo sapiens]
Length = 1193
Score = 41.2 bits (95), Expect = 0.001
Identities = 77/355 (21%), Positives = 142/355 (40%), Gaps = 57/355 (16%)
Query: 15 ILQQVCSKQLPPCNLSKEDLLQNPYFSKLLLN-----LSQHVDESGL---SLTLAKEQAQ 66
+L+ C+ + ++DL F LL + + H + L +++L Q
Sbjct: 584 VLEAFCAHASQRISQLEQDLASMREFRGLLKDAQTQLVGLHAKQEELVQQTVSLTSTLQQ 643
Query: 67 AWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVTSEDKKFHETLEQRLLVTELMR 126
W+ ++L TTW R + E L K + L++R + E
Sbjct: 644 DWRSMQLDYTTWTALLSRSRQLTEKLT---------------VKSQQALQERDVAIE--- 685
Query: 127 LLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRARLQQEVEEQLKKKCFTLLCYYDPN 186
+++E+ +L A L E TE +RL ++ QL+ +L D
Sbjct: 686 -----EKQEVSRVLEQVSAQLEECKGQTEQLELENSRLATDLRAQLQ-----ILANMDSQ 735
Query: 187 -SDADSETVKAAKVWKLAEVLVGEQQQCQD--AKSQQKEQMLL------LEKKSAAYSQV 237
+ S+ A+ + + L+ + Q + A QKE+M L L+++ A ++
Sbjct: 736 LKELQSQHTHCAQDLAMKDELLCQLTQSNEEQAAQWQKEEMALKHMQAELQQQQAVLAKE 795
Query: 238 LLRCLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVE 297
+ L+ QE+++ EL ++ Q +K +L+ R + + L DT +
Sbjct: 796 VRDLKETLEFADQENQV-AHLELGQVECQ---LKTTLEVLRERSLQCENLKDTVENLTAK 851
Query: 298 VHRLIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDRL-VKEYTVLKQATENK 351
+ I D QEQD+E +RQ +L E+ L + T LK+ TE +
Sbjct: 852 LASTIADN-------QEQDLEKTRQYSQKLGLLTEQLQSLTLFLQTKLKEKTEQE 899
>gi|226493512 coiled-coil domain containing 81 isoform 1 [Homo
sapiens]
Length = 652
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 5/155 (3%)
Query: 115 LEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRAR-LQQEVEE-QL 172
L+Q L++ + QE EI E D LE + LTE+ RA+ L+ ++EE Q
Sbjct: 423 LKQEEYSRSLLKQMDNRQENEIKQRQYRELMDRLEQVQLTEELAAQRAKFLKDKMEETQC 482
Query: 173 KKKCFTLLCYYDPNSDADSETVKAAKVW--KLAEVLVGEQQQCQDAKSQQKEQMLLLEKK 230
K+ P+ E + ++ E++V +Q++ Q+ Q E ++K
Sbjct: 483 YKRALDAQIKNKPSRLPPFEPDSSEPIFGKNEGELMVEKQKREQNYMKHQLEAAANHKRK 542
Query: 231 SAAYSQV-LLRCLTLLQRLLQEHRLKTQSELDRIN 264
+ + V R L +LQR +EH +EL+R+N
Sbjct: 543 AILHQLVDQRRDLQMLQRTQREHLADRTAELERVN 577
>gi|226528772 coiled-coil domain containing 81 isoform 2 [Homo
sapiens]
Length = 562
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/155 (27%), Positives = 72/155 (46%), Gaps = 5/155 (3%)
Query: 115 LEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRAR-LQQEVEE-QL 172
L+Q L++ + QE EI E D LE + LTE+ RA+ L+ ++EE Q
Sbjct: 333 LKQEEYSRSLLKQMDNRQENEIKQRQYRELMDRLEQVQLTEELAAQRAKFLKDKMEETQC 392
Query: 173 KKKCFTLLCYYDPNSDADSETVKAAKVW--KLAEVLVGEQQQCQDAKSQQKEQMLLLEKK 230
K+ P+ E + ++ E++V +Q++ Q+ Q E ++K
Sbjct: 393 YKRALDAQIKNKPSRLPPFEPDSSEPIFGKNEGELMVEKQKREQNYMKHQLEAAANHKRK 452
Query: 231 SAAYSQV-LLRCLTLLQRLLQEHRLKTQSELDRIN 264
+ + V R L +LQR +EH +EL+R+N
Sbjct: 453 AILHQLVDQRRDLQMLQRTQREHLADRTAELERVN 487
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 40.8 bits (94), Expect = 0.002
Identities = 29/127 (22%), Positives = 69/127 (54%), Gaps = 2/127 (1%)
Query: 177 FTLLCYYDPNSDADSETVKAAKV-WKLAEVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYS 235
F+L NSD + + ++ ++ E L+ +Q Q ++ +++ L++ ++A+
Sbjct: 837 FSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQ 896
Query: 236 QVLLRCLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEK 295
V+ L+ L+ +E +L +++ A+ E+K +L+ ++EL++LS+T ++EK
Sbjct: 897 NVVAETLSALENKEKELQL-LNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEK 955
Query: 296 VEVHRLI 302
E+ +I
Sbjct: 956 KEMSSII 962
Score = 29.6 bits (65), Expect = 4.4
Identities = 44/221 (19%), Positives = 91/221 (41%), Gaps = 34/221 (15%)
Query: 161 RARLQQEVEEQLKKKCFTLLCYYDPNSDADSE--TVKAAKVWKLAEVLVGEQQQCQDA-- 216
+A+++ +E++ KC L D S T K+ KL E L ++Q + A
Sbjct: 324 KAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARC 383
Query: 217 ------KSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQE-------HRLKTQSELDRI 263
K ++KE L ++ ++ + C+ + RL QE H + Q+ELD++
Sbjct: 384 SLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNV-LQAELDKL 442
Query: 264 NAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRD--------------RLEGA 309
+ +++ K ++ + +++ E+ R + + +
Sbjct: 443 TSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREV 502
Query: 310 IHLQEQDMENSRQVLNSYEVLGEEFD-RLVKEYTVLKQATE 349
HL E +++N +Q LN + EE + + T+L+ E
Sbjct: 503 CHL-EAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQE 542
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 40.4 bits (93), Expect = 0.002
Identities = 72/321 (22%), Positives = 131/321 (40%), Gaps = 39/321 (12%)
Query: 30 SKEDLLQNPYFSKLL-LNLSQHVDESGLSLTLAKEQAQAWKEVRLHKTTWLRSEILHRVI 88
SKE LQ+ + L +L E L + KE + + + L K +SE L +
Sbjct: 745 SKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTR-LDLQK----KSEALESIK 799
Query: 89 QELLV---DYYVKIQDTNVTSEDKKF-HETLEQRL--LVTELMRLLGPSQEREIPPLLGL 142
Q+L + + QD S++ K HE L R+ VTEL ++ +
Sbjct: 800 QKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVK-------------M 846
Query: 143 EKADLLELMPLTEDFVWMRARLQQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKL 202
EK L+ + +D + +V + LK + N + + K K
Sbjct: 847 EKEALMTELSTVKDKL-------SKVSDSLKNSKSE---FEKENQKGKAAILDLEKTCK- 895
Query: 203 AEVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSELD- 261
E+ Q Q ++ +QKE LEK+ A Q+ L ++ ++L+Q Q+E +
Sbjct: 896 -ELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEE 954
Query: 262 -RINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENS 320
++ E+K + K ++E L+ ++K E+ ++ +L A + E
Sbjct: 955 QQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKI 1014
Query: 321 RQVLNSYEVLGEEFDRLVKEY 341
+ N+YE E F +L ++
Sbjct: 1015 SVLQNNYEKSQETFKQLQSDF 1035
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 39.3 bits (90), Expect = 0.006
Identities = 70/314 (22%), Positives = 124/314 (39%), Gaps = 54/314 (17%)
Query: 88 IQELLVDYYVKIQDTNVTSEDKKFH-ETLEQRLLVTELMRLLGPSQEREIPP-------L 139
+QE + ++I+ S + + H E+L+Q+L ++L ++ G RE+ P L
Sbjct: 1342 LQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQL-QIAGLEHLRELQPKLDELQKL 1400
Query: 140 LGLEKADLLELMPLTEDFVWMRARLQQEVEEQ--LKKKCFTLL----------------- 180
+ ++ D+ L + ++Q E+ EQ L K T L
Sbjct: 1401 ISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1460
Query: 181 ---CYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQQKEQML-------LLEKK 230
P + K KL L+ ++ ++ KS Q+E L L +
Sbjct: 1461 LCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSL 1520
Query: 231 SAAYSQVLLRCL---TLLQRL--LQEHRLKTQSELDR--INAQYLEVKCGAMILKLRMEE 283
+ SQV + T+L RL LQE R K +E+DR + Q L C E
Sbjct: 1521 ADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSC---------ES 1571
Query: 284 LKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDRLVKEYTV 343
LK+ + T +K ++ + I I + E +++ YE+L + ++ + E
Sbjct: 1572 LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1631
Query: 344 LKQATENKRWALQE 357
++ E R QE
Sbjct: 1632 IQHVVEAVRQEKQE 1645
Score = 33.5 bits (75), Expect = 0.31
Identities = 66/283 (23%), Positives = 114/283 (40%), Gaps = 43/283 (15%)
Query: 80 RSEILHRVIQELLVDYYVKIQDTNVTSEDKKFHETLEQRLLVTELMRLLGPSQEREIPPL 139
+SE + L + ++ +V S+ K+ E LE+RL E L +E
Sbjct: 2088 QSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDA 2147
Query: 140 LGLEKADLLELMPLTEDFVWMRARLQQEVEEQLKKKCFTLLCYYDPNS---DADSETVKA 196
L EK L E + + + + + Q+++E L L + S D +
Sbjct: 2148 LRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDE 2207
Query: 197 AKVW--KLAEVLVGEQQQ-------CQDAKSQQKEQMLLLEK---------------KSA 232
AK W K ++ + ++++ C K Q ++ + +E+ +S
Sbjct: 2208 AKKWERKFSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK 2267
Query: 233 AYSQVLLR---CLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSD 289
A ++V L+ C TL Q + S+L+ ++L + KL ELK L D
Sbjct: 2268 AQTEVQLQQKVCDTL-----QGENKELLSQLEE--TRHLYHSSQNELAKLE-SELKSLKD 2319
Query: 290 TYT--VEKVEVHRLIRDRLEGAIHLQEQDMENSRQVLNSYEVL 330
T +E + + LEG I QE D++NS+ SYE L
Sbjct: 2320 QLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK---FSYEQL 2359
>gi|55769583 progesterone-induced blocking factor 1 [Homo sapiens]
Length = 757
Score = 39.3 bits (90), Expect = 0.006
Identities = 77/368 (20%), Positives = 148/368 (40%), Gaps = 67/368 (18%)
Query: 45 LNLSQHVDESGLSL--TLAKEQAQAWKE----VRLHKTTWLRSEILHRV----------- 87
+N+S ++ +SL T+ + + +E VR+ + R E+LH +
Sbjct: 12 VNISSSLESEDISLETTVPTDDISSSEEREGKVRITRQLIERKELLHNIQLLKIELSQKT 71
Query: 88 --IQELLVDYYVKIQDTNVTSEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLGLEKA 145
I L VDY KI++ ++K ++ L Q+ L+T + Q+++ L K
Sbjct: 72 MMIDNLKVDYLTKIEEL-----EEKLNDALHQKQLLTLRLDNQLAFQQKDASKYQELMKQ 126
Query: 146 D----LLELMPLTEDFVWMRAR----------LQQEVEEQLKKKCFTLLCYYDPNSDADS 191
+ LL L E + +R + + E+ +K K F P
Sbjct: 127 EMETILLRQKQLEETNLQLREKAGDVRRNLRDFELTEEQYIKLKAF-------PEDQLSI 179
Query: 192 ETVKAAKVWKLAEVLVGE-----------QQQCQDAKSQQKEQMLLLEKKSAAYSQVLLR 240
+ + ++L L E ++ K+Q K+ E+ YS+V +R
Sbjct: 180 PEYVSVRFYELVNPLRKEICELQVKKNILAEELSTNKNQLKQLTETYEEDRKNYSEVQIR 239
Query: 241 CLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAM---ILKLRMEELKILSDTYTVEKVE 297
C L L +L Q + + N ++ + A+ +++LR + +IL ++ ++ E
Sbjct: 240 CQRLALELADTKQLIQQGDYRQENYDKVKSERDALEQEVIELRRKH-EILEASHMIQTKE 298
Query: 298 VHRLIRD--RLEGAIHLQEQDMEN-SRQVLNSYEVLGEEFDRLVKEYTVLKQATENKRWA 354
L ++ LE + L ++D E +RQ + E DRL + L+ E + A
Sbjct: 299 RSELSKEVVTLEQTVTLLQKDKEYLNRQNMELSVRCAHEEDRLER----LQAQLEESKKA 354
Query: 355 LQEFSKVY 362
+E + Y
Sbjct: 355 REEMYEKY 362
Score = 31.2 bits (69), Expect = 1.5
Identities = 60/294 (20%), Positives = 120/294 (40%), Gaps = 40/294 (13%)
Query: 89 QELLVDYYVKIQDTNVTSEDKKFHETLEQRLLVT--ELMRLLGPSQEREIPPLLGLEKAD 146
+E + + YV +D T + K H+ LEQ L T E+ +L S+E + + +
Sbjct: 355 REEMYEKYVASRDHYKTEYENKLHDELEQIRLKTNQEIDQLRNASRE--------MYERE 406
Query: 147 LLELMPLTEDFVWMRARLQQEVEEQLKKKCFTLLCYYDPNSDADS-----------ETVK 195
L ++ V + R ++ L+K L Y + +S ++ +
Sbjct: 407 NRNLREARDNAVAEKERAVMAEKDALEKHDQLLDRYRELQLSTESKVTEFLHQSKLKSFE 466
Query: 196 AAKVWKLAEVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRL- 254
+ +V L E QCQ + ++++ +L K+ + + +T LQ EH+
Sbjct: 467 SERVQLLQEETARNLTQCQLECEKYQKKLEVLTKEFYSLQASSEKRITELQAQNSEHQAR 526
Query: 255 -----KTQSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGA 309
K + ELD I Q E++ +E + + +Y V + RL+ +
Sbjct: 527 LDIYEKLEKELDEIIMQTAEIE--------NEDEAERVLFSYGY-GANVPTTAKRRLKQS 577
Query: 310 IHLQEQDMENSRQVLNSYEVLGEEFDRLVKEYTVLKQATENKRWALQEFSKVYR 363
+HL + ++ +Q NS ++ ++ + + T L Q + L + + YR
Sbjct: 578 VHLARRVLQLEKQ--NS--LILKDLEHRKDQVTQLSQELDRANSLLNQTQQPYR 627
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 38.9 bits (89), Expect = 0.007
Identities = 76/348 (21%), Positives = 132/348 (37%), Gaps = 29/348 (8%)
Query: 11 EGMEILQQVCSKQLPPCNLSKEDLLQNPYFSKLLLNLSQHVDESGLSLTLAKEQAQAWKE 70
E + LQ+ + NL+K+DLL +LL+ + + E Q +E
Sbjct: 1864 EAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEE 1923
Query: 71 VRLHKTTWLRSEI----LHRVIQELLVDYYVKIQDTNVTS-EDKKFHETLEQRLLVTELM 125
+ + L++EI L V QE++ K +++ + E K +Q L EL
Sbjct: 1924 TKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKEL- 1982
Query: 126 RLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRA---------RLQQEVEEQLKKKC 176
Q+ ++ +L A + L E+ W + R E E+QL +K
Sbjct: 1983 ----TDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKS 2038
Query: 177 FTLLCYYDPNSDADSETVKAAKV-------WKLAEVLVGEQQQCQDAKSQQKEQMLLLEK 229
LL +ADS + + K AE V ++ + Q E+ LL +K
Sbjct: 2039 GELLAL---QKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQK 2095
Query: 230 KSAAYSQVLLRCLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSD 289
+ + Q + + L+ + E + EL+++ +Y E+K K +SD
Sbjct: 2096 QENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISD 2155
Query: 290 TYTVEKVEVHRLIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDRL 337
K EV IR L+ + + +L E L E + L
Sbjct: 2156 AMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESL 2203
Score = 29.3 bits (64), Expect = 5.8
Identities = 34/150 (22%), Positives = 67/150 (44%), Gaps = 13/150 (8%)
Query: 210 QQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQS-----ELDRIN 264
+Q+ D + Q ++Q + K + + +L + + +K Q +LD +N
Sbjct: 509 RQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMN 568
Query: 265 AQY--LEVKCGAMILKL--RMEELKILSDTYTVEKVEVHRLIRDRLEGAIH-LQE---QD 316
QY LE + ++ ++ EE+K L + T ++ + ++ LEG I LQE
Sbjct: 569 KQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTI 628
Query: 317 MENSRQVLNSYEVLGEEFDRLVKEYTVLKQ 346
+ Q N L +E + L++ T ++Q
Sbjct: 629 KGQATQAQNECRKLRDEKETLLQRLTEVEQ 658
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 38.1 bits (87), Expect = 0.012
Identities = 61/283 (21%), Positives = 121/283 (42%), Gaps = 39/283 (13%)
Query: 98 KIQDTNVTSEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLG-----LEKADLLELMP 152
K Q T +TSE + E L++RL E ++ L +++ ++ L +E+ + + M
Sbjct: 306 KEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMV 365
Query: 153 LTEDFVWMRARLQQEVEE--QLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVLVGEQ 210
+ E M L+ + EE QL+ + + + + ++ +AA ++ E +
Sbjct: 366 IAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAA--FEELEKALSTA 423
Query: 211 QQCQDA----KSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSELDRINAQ 266
Q+ ++A K++ EQ+ +EK S +E R+ Q EL R+ +
Sbjct: 424 QKTEEARRKLKAEMDEQIKTIEKTS------------------EEERISLQQELSRVKQE 465
Query: 267 YLEV------KCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENS 320
++V + A + KL +EL T + R +++++ A+ + +
Sbjct: 466 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKI 525
Query: 321 RQVLNSYEVLGEEFDRLVKEYTVLKQATENKRWALQEFSKVYR 363
Q E L E L K+ + +ENK LQ+ ++ YR
Sbjct: 526 SQEKEQQESLALEELELQKK--AILTESENKLRDLQQEAETYR 566
Score = 32.0 bits (71), Expect = 0.89
Identities = 37/147 (25%), Positives = 67/147 (45%), Gaps = 25/147 (17%)
Query: 227 LEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSELDRINAQYLEVKCGAMILKLRMEELKI 286
L+++ +L RC +Q ++ L T SE + + Q E R++EL+
Sbjct: 284 LQQRVKRQENLLKRCKETIQSHKEQCTLLT-SEKEALQEQLDE----------RLQELEK 332
Query: 287 LSDTYTVEKVEVHRLIRDRLEGAIHLQEQD-----MENSRQVLNSYEVLGEEFDRL---V 338
+ D + EK ++ +RD + I EQD E RQ+ + E+ EE +L +
Sbjct: 333 IKDLHMAEKTKLITQLRD-AKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRI 391
Query: 339 KEYT-----VLKQATENKRWALQEFSK 360
K+ T + +Q +++R A +E K
Sbjct: 392 KQMTTQGEELREQKEKSERAAFEELEK 418
Score = 29.6 bits (65), Expect = 4.4
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 10/162 (6%)
Query: 201 KLAEVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHR----LKT 256
K +E Q + ++ KE + LE KS + + L + L Q+++ LK
Sbjct: 1441 KFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKG 1500
Query: 257 QSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQD 316
+ E D+ + E LK + + L D T + +E+ L + L+ + Q++D
Sbjct: 1501 EMEDDKSKMEKKESNLETE-LKSQTARIMELEDHITQKTIEIESL-NEVLKN--YNQQKD 1556
Query: 317 MENSR--QVLNSYEVLGEEFDRLVKEYTVLKQATENKRWALQ 356
+E+ Q L ++ LGEE D VKE EN+ ++++
Sbjct: 1557 IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMK 1598
Score = 28.5 bits (62), Expect = 9.8
Identities = 66/301 (21%), Positives = 119/301 (39%), Gaps = 38/301 (12%)
Query: 79 LRSEILHRVIQELLVDYYVKIQDTNVTSEDKKFHETLEQRLLVTELMRLLGP-------S 131
+R + +HRV E L Y K+Q K E LE+ L+ P +
Sbjct: 1864 VRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEA 1923
Query: 132 QEREIP-PLLGLEKADL---LELMPLTEDFVWMRARLQQEVEEQLKKKCFTLLCYYDPNS 187
Q ++ L G E+ E++ L +D +R QQE+ E LKK+ YD
Sbjct: 1924 QHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQEL-EILKKE-------YDQER 1975
Query: 188 DADSETVKAAKVWKLAEVLVGEQQQCQDAKSQ--QKEQMLLLEKKSAAYSQVLLRCLTLL 245
+ + + K L +Q ++ +Q QKEQ L + K + + + +
Sbjct: 1976 EEKIKQEQEDLELKHNSTL---KQLMREFNTQLAQKEQELEMTIK-----ETINKAQEVE 2027
Query: 246 QRLLQEHRLKTQSELDRINAQYLEVKCGAM----ILKLRMEELKILSDTYTVEKVEVHRL 301
LL+ H+ +T L +I + ++K A IL R EE+ + E+ +
Sbjct: 2028 AELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKK 2087
Query: 302 IRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDRLVKEYTVLKQATENKRWALQEFSKV 361
+ +LE QE++ N + + + L+ + + +Q + L++ K
Sbjct: 2088 YQQKLE-----QEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKK 2142
Query: 362 Y 362
Y
Sbjct: 2143 Y 2143
>gi|28269672 serologically defined colon cancer antigen 8 [Homo
sapiens]
Length = 713
Score = 37.7 bits (86), Expect = 0.016
Identities = 40/148 (27%), Positives = 70/148 (47%), Gaps = 17/148 (11%)
Query: 209 EQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSELDRINAQ-- 266
+Q + Q K++ EQ LLL ++ +++ C TL ++L Q + KT+SE+ +++ +
Sbjct: 572 QQMEAQHDKTEN-EQYLLLTSQNTFLTKLKEECCTLAKKLEQISQ-KTRSEIAQLSQEKR 629
Query: 267 YLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRL-------EGAIHLQEQDMEN 319
Y K G L+ R EEL + V+ VH ++ RL + Q +
Sbjct: 630 YTYDKLGK--LQRRNEEL----EEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSK 683
Query: 320 SRQVLNSYEVLGEEFDRLVKEYTVLKQA 347
Q+L + L EE DRL + + Q+
Sbjct: 684 QNQLLLERQSLSEEVDRLRTQLPSMPQS 711
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 37.4 bits (85), Expect = 0.021
Identities = 44/210 (20%), Positives = 91/210 (43%), Gaps = 14/210 (6%)
Query: 160 MRARLQQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQ 219
M+ Q++ E LK C L + E ++ + W+ ++G+++ + + +
Sbjct: 1003 MQLTSQKQTMEALKTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDEKSQFECRVR 1062
Query: 220 QKEQMLLLEKKSAAYS-QVLLRCLTLLQRLLQEHR-----LKTQSELDRINAQYLEVKCG 273
+ ++ML EK+S A + Q + +++ ++EH+ L+ + ++ A+ L K
Sbjct: 1063 ELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLSDKLN 1122
Query: 274 AMILKLRMEELKILSDTYTVEKVEVHRLIRDR-LEGAIHLQEQDMENSRQVLNSYEVLGE 332
+ K M E+ S +K+E R ++ R LE LQ+Q + + L E
Sbjct: 1123 DLEKKHAMLEMNARS---LQQKLETERELKQRLLEEQAKLQQQMDLQKNHIFRLTQGLQE 1179
Query: 333 EFDRLVKEYTVLKQATENKRWALQEFSKVY 362
DR +LK + + L+ +Y
Sbjct: 1180 ALDRA----DLLKTERSDLEYQLENIQVLY 1205
>gi|5803145 ralA binding protein 1 [Homo sapiens]
Length = 655
Score = 36.2 bits (82), Expect = 0.047
Identities = 33/199 (16%), Positives = 87/199 (43%), Gaps = 31/199 (15%)
Query: 165 QQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQQKEQM 224
Q ++E+++++ F L C + + K ++W++ +L +++ ++AK Q+ E
Sbjct: 395 QAGIKEEIRRQEFLLNCLHRDLQGGIKDLSKEERLWEVQRILTALKRKLREAKRQECETK 454
Query: 225 LLLEKKS----------------------AAYSQVLLRC--LTLLQRLLQEHRLKTQSEL 260
+ E S A +++L L +++ L+ + E+
Sbjct: 455 IAQEIASLSKEDVSKEEMNENEEVINILLAQENEILTEQEELLAMEQFLRRQIASEKEEI 514
Query: 261 DRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENS 320
+R+ A+ E++ + EE S++ + ++ E+ ++ D + Q +++E
Sbjct: 515 ERLRAEIAEIQSRQQHGRSETEEYSSESESESEDEEELQIILED-----LQRQNEELEIK 569
Query: 321 RQVLNSYEVLGEEFDRLVK 339
LN + + EE + +++
Sbjct: 570 NNHLN--QAIHEEREAIIE 586
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 35.8 bits (81), Expect = 0.062
Identities = 57/275 (20%), Positives = 121/275 (44%), Gaps = 39/275 (14%)
Query: 89 QELLVDYYVKIQDTNVTSEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLGLEKADLL 148
+E +++Y ++Q+ ++ +++ + L+ + E+ R+ +Q+++ LL EK
Sbjct: 283 KEQMLEYMEQLQEEDLKDMERRQQQKLKMQ---AEIKRINDENQKQKAE-LLAQEKLADQ 338
Query: 149 ELMPLTEDFVWMRARL---QQEVEEQLKKKCFTLLCYYDPNSD--ADSETVKAAKVWKLA 203
+M T+ + A Q+ + + +K+ L + D A+ + ++A +
Sbjct: 339 MVMEFTKKKMAREAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKR----- 393
Query: 204 EVLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSELDRI 263
Q+ D + ++KE+ +K ++ LR L Q +EH L Q + DR
Sbjct: 394 ------NQEVADREWRRKEKENARKKME---TEAELRKSRLEQVAFKEHALAVQVQRDRD 444
Query: 264 NAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENSRQV 323
+ IL+ + E+++ E++E + RL+ A L+ Q EN ++
Sbjct: 445 EFE--------RILRAQREQIE-------KERLEEEKKATGRLQHANELRRQVRENQQKE 489
Query: 324 LNSYEVLGEEFDRLVKEYTVLKQ-ATENKRWALQE 357
+ + EE RL +E ++ E KR L+E
Sbjct: 490 VQNRIATFEEGRRLKEEAQKRRERIDEIKRKKLEE 524
>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
Length = 1012
Score = 35.4 bits (80), Expect = 0.080
Identities = 45/187 (24%), Positives = 77/187 (41%), Gaps = 41/187 (21%)
Query: 165 QQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVLVGEQQQCQDAKSQQKEQM 224
++E+EEQL+ + L ++ D + +K K + L Q + A + E +
Sbjct: 204 KREIEEQLRAEMCQKLKFF---KDTEIAKIKMEAKKKYEKELTMFQNDFEKACQAKSEAL 260
Query: 225 LLLEKKSA---------------AYSQVLLRCLTLLQRLLQEHRLKTQSELDRINAQYLE 269
+L EK + A Q+LL+ + LL+ +E LK + E +N + E
Sbjct: 261 VLREKSTLERIHKHQEIETKEIYAQRQLLLKDMDLLRG--REAELKQRVEAFELNQKLQE 318
Query: 270 VKCGAMILKLRMEELKILSDTYTVEK------------------VEVHRLIRDRL---EG 308
K ++ LR +E I S T ++ + +RLI D E
Sbjct: 319 EKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKDDYIIRTNRLIEDERKNKEK 378
Query: 309 AIHLQEQ 315
A+HLQE+
Sbjct: 379 AVHLQEE 385
>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
Length = 717
Score = 35.4 bits (80), Expect = 0.080
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 23/258 (8%)
Query: 106 SEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELM--PLTEDFVWMRAR 163
SE+ + + L+QR L E +L +++ L E A L E M P E + A+
Sbjct: 181 SEEAEEGDELQQRCLDLERQLMLLSEEKQS----LAQENAGLRERMGRPEGEGTPGLTAK 236
Query: 164 ---LQQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWK-LAEVLVGEQQQCQDAKSQ 219
L Q EQL+++ F L S + E ++ A++ + +AE+ Q A+
Sbjct: 237 KLLLLQSQLEQLQEENFRL------ESGREDERLRCAELEREVAELQHRNQALTSLAQEA 290
Query: 220 Q--KEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQ-SELDRINAQYLEVKCGAMI 276
Q K++M L + S Q+ + +RL + L+ Q +L+ NA + E
Sbjct: 291 QALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE---RTRQ 347
Query: 277 LKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDR 336
L+ + L ++ +V L R E A+ ++ E R + YE + +E +R
Sbjct: 348 LEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFE-CRNLEEKYESVTKEKER 406
Query: 337 LVKEYTVLKQATENKRWA 354
L+ E L++A E R A
Sbjct: 407 LLAERDSLREANEELRCA 424
>gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]
Length = 719
Score = 35.4 bits (80), Expect = 0.080
Identities = 65/258 (25%), Positives = 113/258 (43%), Gaps = 23/258 (8%)
Query: 106 SEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELM--PLTEDFVWMRAR 163
SE+ + + L+QR L E +L +++ L E A L E M P E + A+
Sbjct: 181 SEEAEEGDELQQRCLDLERQLMLLSEEKQS----LAQENAGLRERMGRPEGEGTPGLTAK 236
Query: 164 ---LQQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWK-LAEVLVGEQQQCQDAKSQ 219
L Q EQL+++ F L S + E ++ A++ + +AE+ Q A+
Sbjct: 237 KLLLLQSQLEQLQEENFRL------ESGREDERLRCAELEREVAELQHRNQALTSLAQEA 290
Query: 220 Q--KEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQ-SELDRINAQYLEVKCGAMI 276
Q K++M L + S Q+ + +RL + L+ Q +L+ NA + E
Sbjct: 291 QALKDEMDELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAE---RTRQ 347
Query: 277 LKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENSRQVLNSYEVLGEEFDR 336
L+ + L ++ +V L R E A+ ++ E R + YE + +E +R
Sbjct: 348 LEDELRRAGSLRAQLEAQRRQVQELQGQRQEEAMKAEKWLFE-CRNLEEKYESVTKEKER 406
Query: 337 LVKEYTVLKQATENKRWA 354
L+ E L++A E R A
Sbjct: 407 LLAERDSLREANEELRCA 424
>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
Length = 514
Score = 35.0 bits (79), Expect = 0.10
Identities = 64/307 (20%), Positives = 129/307 (42%), Gaps = 61/307 (19%)
Query: 88 IQELLV----DYYVKIQDTNVTSEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLGLE 143
++ELL +Y+ ++Q T E+KK + E +LL E+E + E
Sbjct: 101 LRELLALEENEYFTEMQLKKETIEEKKDR--------MREKTKLLKEKNEKERQDFVA-E 151
Query: 144 KADL----------LELMPLTEDFVWMRARLQQEVEEQLKKK------CFTLLCYYDPNS 187
K D +EL+ + + V + Q E+L ++ F+ L D +
Sbjct: 152 KLDQQFRERCEELRVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSKLWEEDRLA 211
Query: 188 DADSETVKAAKVWKLAE-VLVGEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQ 246
E +A + +L E +G Q K+Q++ LL E+++
Sbjct: 212 KEKREAQEARRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEA--------------- 256
Query: 247 RLLQEH--RLKTQSELDRINAQYLEVKCGAMILKLRMEELKILSDTYTVEK----VEVHR 300
RL++ + ++K ++E D + Q + + ++ K E ++ + Y E+ V R
Sbjct: 257 RLVESNNAQIKHENEQDMLKKQKAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQR 316
Query: 301 LIRDRLEGAIHLQE--QDMENSRQVLNSY--------EVLGEEFDRLVKEYTVLKQATEN 350
++D E A ++ +DM +++ + Y + +EFDR+++E K A ++
Sbjct: 317 ALQDLQEEADKKKQKREDMIREQKIYHKYLAQRREEEKAQEKEFDRILEEDKAKKLAEKD 376
Query: 351 KRWALQE 357
K L++
Sbjct: 377 KELRLEK 383
>gi|223029422 SKI-like isoform 3 [Homo sapiens]
Length = 664
Score = 34.7 bits (78), Expect = 0.14
Identities = 38/186 (20%), Positives = 84/186 (45%), Gaps = 19/186 (10%)
Query: 46 NLSQHVDESGLSLTLAKEQAQAWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVT 105
NL + +++ G+ L A K+V + + ++++E++ Y + + N+
Sbjct: 476 NLVRDINKVGIGLVAAASSPLLVKDV-------ICEDDKGKIMEEVMRTYLKQQEKLNLI 528
Query: 106 SEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRARLQ 165
+ K+ + + L ++ M+ L Q+ L L+ + E+F + L+
Sbjct: 529 LQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRM----EEFYVEQKDLE 584
Query: 166 QEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVL---VGEQQQCQDAKSQQKE 222
+++E+ +K+KC D N + D E A ++ +L + L ++Q+ QD Q++E
Sbjct: 585 KKLEQIMKQKCTC-----DSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQERE 639
Query: 223 QMLLLE 228
LE
Sbjct: 640 ARQKLE 645
>gi|223029420 SKI-like isoform 2 [Homo sapiens]
Length = 638
Score = 34.7 bits (78), Expect = 0.14
Identities = 38/186 (20%), Positives = 84/186 (45%), Gaps = 19/186 (10%)
Query: 46 NLSQHVDESGLSLTLAKEQAQAWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVT 105
NL + +++ G+ L A K+V + + ++++E++ Y + + N+
Sbjct: 450 NLVRDINKVGIGLVAAASSPLLVKDV-------ICEDDKGKIMEEVMRTYLKQQEKLNLI 502
Query: 106 SEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRARLQ 165
+ K+ + + L ++ M+ L Q+ L L+ + E+F + L+
Sbjct: 503 LQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRM----EEFYVEQKDLE 558
Query: 166 QEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVL---VGEQQQCQDAKSQQKE 222
+++E+ +K+KC D N + D E A ++ +L + L ++Q+ QD Q++E
Sbjct: 559 KKLEQIMKQKCTC-----DSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQERE 613
Query: 223 QMLLLE 228
LE
Sbjct: 614 ARQKLE 619
>gi|223029418 SKI-like isoform 1 [Homo sapiens]
Length = 684
Score = 34.7 bits (78), Expect = 0.14
Identities = 38/186 (20%), Positives = 84/186 (45%), Gaps = 19/186 (10%)
Query: 46 NLSQHVDESGLSLTLAKEQAQAWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVT 105
NL + +++ G+ L A K+V + + ++++E++ Y + + N+
Sbjct: 496 NLVRDINKVGIGLVAAASSPLLVKDV-------ICEDDKGKIMEEVMRTYLKQQEKLNLI 548
Query: 106 SEDKKFHETLEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPLTEDFVWMRARLQ 165
+ K+ + + L ++ M+ L Q+ L L+ + E+F + L+
Sbjct: 549 LQKKQQLQMEVKMLSSSKSMKELTEEQQNLQKELESLQNEHAQRM----EEFYVEQKDLE 604
Query: 166 QEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVL---VGEQQQCQDAKSQQKE 222
+++E+ +K+KC D N + D E A ++ +L + L ++Q+ QD Q++E
Sbjct: 605 KKLEQIMKQKCTC-----DSNLEKDKEAEYAGQLAELRQRLDHAEADRQELQDELRQERE 659
Query: 223 QMLLLE 228
LE
Sbjct: 660 ARQKLE 665
>gi|62243374 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 34.7 bits (78), Expect = 0.14
Identities = 57/248 (22%), Positives = 101/248 (40%), Gaps = 52/248 (20%)
Query: 98 KIQDTNVTSEDKKFHET----LEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPL 153
KIQ+ + E + HE LEQ+L + E + + + E+ L LE+ EL L
Sbjct: 207 KIQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLER----ELKQL 262
Query: 154 TEDFVWMRAR-----LQQEVEEQLKKKCFTLLCYYDPNSDADSETVKA-AKV--WKLAEV 205
E+ +R L QE E L++K + + E + AK+ W+ +
Sbjct: 263 REESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERLDQ 322
Query: 206 LVGEQQQCQDAKSQ-----QKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSEL 260
+G + + S+ Q+ ++ L +K SA S R L++ R + Q EL
Sbjct: 323 TMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSA---------RGLEKARQQLQEEL 373
Query: 261 DRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENS 320
+++ Q LE + +K E H + RL+ + L ++ +
Sbjct: 374 RQVSGQLLEER----------------------KKRETHEALARRLQKRVLLLTKERDGM 411
Query: 321 RQVLNSYE 328
R +L SY+
Sbjct: 412 RAILGSYD 419
>gi|62243369 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 34.7 bits (78), Expect = 0.14
Identities = 57/248 (22%), Positives = 101/248 (40%), Gaps = 52/248 (20%)
Query: 98 KIQDTNVTSEDKKFHET----LEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPL 153
KIQ+ + E + HE LEQ+L + E + + + E+ L LE+ EL L
Sbjct: 207 KIQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLER----ELKQL 262
Query: 154 TEDFVWMRAR-----LQQEVEEQLKKKCFTLLCYYDPNSDADSETVKA-AKV--WKLAEV 205
E+ +R L QE E L++K + + E + AK+ W+ +
Sbjct: 263 REESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERLDQ 322
Query: 206 LVGEQQQCQDAKSQ-----QKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSEL 260
+G + + S+ Q+ ++ L +K SA S R L++ R + Q EL
Sbjct: 323 TMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSA---------RGLEKARQQLQEEL 373
Query: 261 DRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENS 320
+++ Q LE + +K E H + RL+ + L ++ +
Sbjct: 374 RQVSGQLLEER----------------------KKRETHEALARRLQKRVLLLTKERDGM 411
Query: 321 RQVLNSYE 328
R +L SY+
Sbjct: 412 RAILGSYD 419
>gi|62243332 MAD1-like 1 protein [Homo sapiens]
Length = 718
Score = 34.7 bits (78), Expect = 0.14
Identities = 57/248 (22%), Positives = 101/248 (40%), Gaps = 52/248 (20%)
Query: 98 KIQDTNVTSEDKKFHET----LEQRLLVTELMRLLGPSQEREIPPLLGLEKADLLELMPL 153
KIQ+ + E + HE LEQ+L + E + + + E+ L LE+ EL L
Sbjct: 207 KIQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLER----ELKQL 262
Query: 154 TEDFVWMRAR-----LQQEVEEQLKKKCFTLLCYYDPNSDADSETVKA-AKV--WKLAEV 205
E+ +R L QE E L++K + + E + AK+ W+ +
Sbjct: 263 REESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERLDQ 322
Query: 206 LVGEQQQCQDAKSQ-----QKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSEL 260
+G + + S+ Q+ ++ L +K SA S R L++ R + Q EL
Sbjct: 323 TMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSA---------RGLEKARQQLQEEL 373
Query: 261 DRINAQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENS 320
+++ Q LE + +K E H + RL+ + L ++ +
Sbjct: 374 RQVSGQLLEER----------------------KKRETHEALARRLQKRVLLLTKERDGM 411
Query: 321 RQVLNSYE 328
R +L SY+
Sbjct: 412 RAILGSYD 419
>gi|31377798 rabaptin, RAB GTPase binding effector protein 1 isoform
1 [Homo sapiens]
Length = 862
Score = 34.7 bits (78), Expect = 0.14
Identities = 46/217 (21%), Positives = 87/217 (40%), Gaps = 19/217 (8%)
Query: 160 MRARLQQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLA-EVLVGEQQQ-CQDAK 217
M + ++E+ +K K L + +S+ S + A + A E+L+ E QQ AK
Sbjct: 563 MLRQANDQLEKTMKDKQ-ELEDFIKQSSEDSSHQISALVLRAQASEILLEELQQGLSQAK 621
Query: 218 SQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRL-------------KTQSELDRIN 264
+EQM +L + S+ L+R L +H L T L +
Sbjct: 622 RDVQEQMAVLMQSREQVSEELVRLQKDNDSLQGKHSLHVSLQQAEDFILPDTTEALRELV 681
Query: 265 AQYLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGAIHLQEQDMENSRQVL 324
+Y E +EE + E+++ + +++ LE + L ++EN ++ +
Sbjct: 682 LKYREDIINVRTAADHVEEKLKAEILFLKEQIQAEQCLKENLEETLQL---EIENCKEEI 738
Query: 325 NSYEVLGEEFDRLVKEYTVLKQATENKRWALQEFSKV 361
S L E +R+ E L+ K L+ ++
Sbjct: 739 ASISSLKAELERIKVEKGQLESTLREKSQQLESLQEI 775
>gi|45505178 cancer antigen 1 [Homo sapiens]
Length = 641
Score = 34.3 bits (77), Expect = 0.18
Identities = 56/267 (20%), Positives = 119/267 (44%), Gaps = 35/267 (13%)
Query: 94 DYYVKIQDTNVTSEDKKFHETLEQRLLVTELMRLLGPSQEREIPPL----LGLEKADLLE 149
D+ + ED +E L++ ++ QE I L L LEK
Sbjct: 152 DWEQSAESLQPVQEDMALNEVLQK-------LKHTNRKQEVRIQELQCSNLYLEKRVKEL 204
Query: 150 LMPLTEDFVWMRA--RLQQEVEEQLKKKCFTLLCYYDPNSDADSETVKAAKVWKLAEVLV 207
M +T+ V++ +L++ VEE ++ K +L ++T K + L EVL
Sbjct: 205 QMKITKQQVFIDVINKLKENVEELIEDKYKIIL--------EKNDTKKTLQ--NLEEVLA 254
Query: 208 GEQQQCQDAKSQQKEQMLLLEKKSAAYSQVLLRCLTLLQRLLQEHRLKTQSELDR-INAQ 266
Q+ Q++++ ++ L +K A Y + R +T +Q+ + + E+D+ ++ +
Sbjct: 255 NTQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQ--KNKSVSQYLEMDKTLSKK 312
Query: 267 YLEVKCGAMILKLRMEELKILSDTYTVEKVEVHRLIRDRLEGA-IHLQEQDMENSRQVLN 325
EV+ R+++LK + T +++ + ++ E + LQE+ + ++ L
Sbjct: 313 EEEVE--------RLQQLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQKLEKENLE 364
Query: 326 SYEVLGEEFDRLVKEYTVLKQATENKR 352
+ L ++L+ + L+ +EN+R
Sbjct: 365 ERQKLKSRLEKLLTQVRNLQFMSENER 391
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 34.3 bits (77), Expect = 0.18
Identities = 41/171 (23%), Positives = 80/171 (46%), Gaps = 25/171 (14%)
Query: 197 AKVWKLAEVLVGEQQQCQDAKSQQKEQML--LLEKKSAAYSQVLLRCLTLLQRLLQEHRL 254
A++ L + + EQQ+ + K QQKE + LL+++ S + + + + +++E L
Sbjct: 230 AEMQNLKQKFILEQQERE--KLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNL 287
Query: 255 ------KTQSELDRINAQYLEVKCGAMILKL------RMEELKILSDTYTVEKVEVHRLI 302
+T ELD++ Q E + ++ +L R EELK+L + ++ E+ +
Sbjct: 288 FEEELKQTLDELDKL--QQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSS 345
Query: 303 RDRLEGAIHLQE------QDMENSRQVLNSYEVL-GEEFDRLVKEYTVLKQ 346
+ + LQE Q +E+ SY+ L E + L E + L++
Sbjct: 346 AAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQE 396
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 34.3 bits (77), Expect = 0.18
Identities = 41/171 (23%), Positives = 80/171 (46%), Gaps = 25/171 (14%)
Query: 197 AKVWKLAEVLVGEQQQCQDAKSQQKEQML--LLEKKSAAYSQVLLRCLTLLQRLLQEHRL 254
A++ L + + EQQ+ + K QQKE + LL+++ S + + + + +++E L
Sbjct: 317 AEMQNLKQKFILEQQERE--KLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNL 374
Query: 255 ------KTQSELDRINAQYLEVKCGAMILKL------RMEELKILSDTYTVEKVEVHRLI 302
+T ELD++ Q E + ++ +L R EELK+L + ++ E+ +
Sbjct: 375 FEEELKQTLDELDKL--QQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSS 432
Query: 303 RDRLEGAIHLQE------QDMENSRQVLNSYEVL-GEEFDRLVKEYTVLKQ 346
+ + LQE Q +E+ SY+ L E + L E + L++
Sbjct: 433 AAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQE 483
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,093,903
Number of Sequences: 37866
Number of extensions: 544754
Number of successful extensions: 2495
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 149
Number of HSP's that attempted gapping in prelim test: 2359
Number of HSP's gapped (non-prelim): 256
length of query: 363
length of database: 18,247,518
effective HSP length: 104
effective length of query: 259
effective length of database: 14,309,454
effective search space: 3706148586
effective search space used: 3706148586
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.