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Search of human proteins with 88758594
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88758594 phosducin-like [Homo sapiens]
(301 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88758594 phosducin-like [Homo sapiens] 601 e-172
gi|32967591 phosducin isoform a [Homo sapiens] 225 4e-59
gi|12408668 phosducin isoform b [Homo sapiens] 197 1e-50
gi|51944950 phosducin-like 2 [Homo sapiens] 81 1e-15
gi|13129044 phosducin-like 3 [Homo sapiens] 74 1e-13
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 52 5e-07
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 52 5e-07
gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens] 52 5e-07
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 52 5e-07
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 50 2e-06
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 50 2e-06
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 50 2e-06
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 50 2e-06
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa... 46 5e-05
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa... 46 5e-05
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa... 46 5e-05
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap... 46 5e-05
gi|148746195 trichohyalin [Homo sapiens] 42 7e-04
gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo sa... 42 7e-04
gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo s... 42 7e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 42 9e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 42 9e-04
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 42 9e-04
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 39 0.006
gi|213688415 coiled-coil domain containing 66 isoform 1 [Homo sa... 39 0.006
gi|213688413 coiled-coil domain containing 66 isoform 2 [Homo sa... 39 0.006
gi|95113651 glutaredoxin 3 [Homo sapiens] 38 0.010
gi|171460958 nucleolar protein 10 [Homo sapiens] 38 0.010
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 38 0.010
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 38 0.010
>gi|88758594 phosducin-like [Homo sapiens]
Length = 301
Score = 601 bits (1550), Expect = e-172
Identities = 301/301 (100%), Positives = 301/301 (100%)
Query: 1 MTTLDDKLLGEKLQYYYSSSEDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPK 60
MTTLDDKLLGEKLQYYYSSSEDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPK
Sbjct: 1 MTTLDDKLLGEKLQYYYSSSEDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPK 60
Query: 61 GVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMT 120
GVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMT
Sbjct: 61 GVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMT 120
Query: 121 LKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKS 180
LKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKS
Sbjct: 121 LKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKS 180
Query: 181 IVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTRNALPALLIYK 240
IVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTRNALPALLIYK
Sbjct: 181 IVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTRNALPALLIYK 240
Query: 241 GGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEI 300
GGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEI
Sbjct: 241 GGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEI 300
Query: 301 D 301
D
Sbjct: 301 D 301
>gi|32967591 phosducin isoform a [Homo sapiens]
Length = 246
Score = 225 bits (573), Expect = 4e-59
Identities = 108/232 (46%), Positives = 167/232 (71%), Gaps = 10/232 (4%)
Query: 51 EGISVNTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKD 110
EG + +TGPKGVINDWR+FK LE++ + + +++++S + + KD
Sbjct: 14 EGQATHTGPKGVINDWRKFK-LESQDSDSIPPSKKEILRQMS---------SPQSRNGKD 63
Query: 111 LQEKISGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGF 170
+E++S KM+++E+ +++++++DE L++YR+Q M++M Q+L GP++ V+E+ +G+ F
Sbjct: 64 SKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQF 123
Query: 171 LDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIGASSQFTR 230
L+ I+KE K I+VHIYEDGI G +A+N + CLAAEYP VKFCK+K+S GA +F+
Sbjct: 124 LETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSL 183
Query: 231 NALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVL 282
+ LP LLIYKGGELI NF+ V +Q ++FFA D+E+FL E+GLLPE+EV VL
Sbjct: 184 DVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREVHVL 235
>gi|12408668 phosducin isoform b [Homo sapiens]
Length = 194
Score = 197 bits (500), Expect = 1e-50
Identities = 90/179 (50%), Positives = 137/179 (76%)
Query: 104 EQQKQKDLQEKISGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFE 163
+ + KD +E++S KM+++E+ +++++++DE L++YR+Q M++M Q+L GP++ V+E
Sbjct: 5 QSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYE 64
Query: 164 ISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIG 223
+ +G+ FL+ I+KE K I+VHIYEDGI G +A+N + CLAAEYP VKFCK+K+S G
Sbjct: 65 LETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTG 124
Query: 224 ASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVL 282
A +F+ + LP LLIYKGGELI NF+ V +Q ++FFA D+E+FL E+GLLPE+EV VL
Sbjct: 125 AGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREVHVL 183
>gi|51944950 phosducin-like 2 [Homo sapiens]
Length = 241
Score = 80.9 bits (198), Expect = 1e-15
Identities = 58/210 (27%), Positives = 110/210 (52%), Gaps = 17/210 (8%)
Query: 100 DEEEEQ--QKQKDLQEKISGKMTLKEFAIMNEDQDDEEF--LQQYRKQRMEEMRQQLHKG 155
DE EE + QK+ K KMTL + ++ D+E+ ++ YRK+R++E + L K
Sbjct: 28 DEIEEMVLRLQKEAMVKPFEKMTLAQLKEAEDEFDEEDMQAVETYRKKRLQEWKA-LKKK 86
Query: 156 PQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFC 215
+F ++ EIS G +++ + ++ + +++H+Y IP +N + LA ++P KF
Sbjct: 87 QKFGELREIS-GNQYVNEVTNAEEDVWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKF- 144
Query: 216 KVKSSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLL- 274
VK+ V + N LP + +YK G++ F+ + + G + +LE L E G +
Sbjct: 145 -VKAIVNSCIQHYHDNCLPTIFVYKNGQIEAKFIGIIECGGINLKLEELEWKLAEVGAIQ 203
Query: 275 ------PEKEV--LVLTSVRNSATCHSEDS 296
P K++ ++++S+RN++ DS
Sbjct: 204 TDLEENPRKDMVDMMVSSIRNTSIHDDSDS 233
>gi|13129044 phosducin-like 3 [Homo sapiens]
Length = 239
Score = 74.3 bits (181), Expect = 1e-13
Identities = 63/215 (29%), Positives = 110/215 (51%), Gaps = 19/215 (8%)
Query: 101 EEEEQQKQKDLQE---KISGKMTLKEFAIMNED--QDDEEFLQQYRKQRMEEMRQQLHKG 155
EEE +++Q+ LQ+ K MTL+E ++ ++DE ++ YR++R+ E + K
Sbjct: 30 EEEAEEEQRILQQSVVKTYEDMTLEELEDHEDEFNEEDERAIEMYRRRRLAEWKATKLKN 89
Query: 156 PQFKQVFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFC 215
+F +V EIS G+ ++ + K + + +++H+Y+ GIP +N + LA ++P VKF
Sbjct: 90 -KFGEVLEIS-GKDYVQEVTKAGEGLWVILHLYKQGIPLCALINQHLSGLARKFPDVKFI 147
Query: 216 KVKSSVIGASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLL- 274
K S+ + LP + +Y G++ F+ G + +LE L E G +
Sbjct: 148 KAISTT--CIPNYPDRNLPTIFVYLEGDIKAQFIGPLVFGGMNLTRDELEWKLSESGAIM 205
Query: 275 ------PEK--EVLVLTSVRNSATCHSEDSDLEID 301
P+K E ++L+SVR S DSD E D
Sbjct: 206 TDLEENPKKPIEDVLLSSVRRSVLM-KRDSDSEGD 239
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/193 (22%), Positives = 88/193 (45%), Gaps = 19/193 (9%)
Query: 11 EKLQYYYSSSEDEDSDHEDKDRGRCAPAS-SSVPAEAELAGEGISVNTGPKGVINDWRRF 69
E+ +Y YS SE+ED H ++ P+S +VP E+ L E + + K ++
Sbjct: 317 EETEYEYSGSEEEDDSHGEEGE----PSSIMNVPGESTLRREFLRLQQENKSNSEALKQQ 372
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEE---EEQQKQKDLQEKISGKMTLKEFAI 126
+QL+ +Q+ + ++ L+ + +E EEQQ+++ Q K+ K +
Sbjct: 373 QQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLED 432
Query: 127 M-----NEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSI 181
M E++ E Q+Y+++++EE RQ Q +Q +L + ++Q+
Sbjct: 433 MQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQ------EHAYLKSLQQQQQQQ 486
Query: 182 VIMVHIYEDGIPG 194
+ + +PG
Sbjct: 487 QLQKQQQQQLLPG 499
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/193 (22%), Positives = 88/193 (45%), Gaps = 19/193 (9%)
Query: 11 EKLQYYYSSSEDEDSDHEDKDRGRCAPAS-SSVPAEAELAGEGISVNTGPKGVINDWRRF 69
E+ +Y YS SE+ED H ++ P+S +VP E+ L E + + K ++
Sbjct: 317 EETEYEYSGSEEEDDSHGEEGE----PSSIMNVPGESTLRREFLRLQQENKSNSEALKQQ 372
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEE---EEQQKQKDLQEKISGKMTLKEFAI 126
+QL+ +Q+ + ++ L+ + +E EEQQ+++ Q K+ K +
Sbjct: 373 QQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLED 432
Query: 127 M-----NEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSI 181
M E++ E Q+Y+++++EE RQ Q +Q +L + ++Q+
Sbjct: 433 MQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQ------EHAYLKSLQQQQQQQ 486
Query: 182 VIMVHIYEDGIPG 194
+ + +PG
Sbjct: 487 QLQKQQQQQLLPG 499
>gi|27436917 misshapen/NIK-related kinase isoform 3 [Homo sapiens]
Length = 1332
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/193 (22%), Positives = 88/193 (45%), Gaps = 19/193 (9%)
Query: 11 EKLQYYYSSSEDEDSDHEDKDRGRCAPAS-SSVPAEAELAGEGISVNTGPKGVINDWRRF 69
E+ +Y YS SE+ED H ++ P+S +VP E+ L E + + K ++
Sbjct: 317 EETEYEYSGSEEEDDSHGEEGE----PSSIMNVPGESTLRREFLRLQQENKSNSEALKQQ 372
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEE---EEQQKQKDLQEKISGKMTLKEFAI 126
+QL+ +Q+ + ++ L+ + +E EEQQ+++ Q K+ K +
Sbjct: 373 QQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLED 432
Query: 127 M-----NEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSI 181
M E++ E Q+Y+++++EE RQ Q +Q +L + ++Q+
Sbjct: 433 MQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQ------EHAYLKSLQQQQQQQ 486
Query: 182 VIMVHIYEDGIPG 194
+ + +PG
Sbjct: 487 QLQKQQQQQLLPG 499
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 52.4 bits (124), Expect = 5e-07
Identities = 44/193 (22%), Positives = 88/193 (45%), Gaps = 19/193 (9%)
Query: 11 EKLQYYYSSSEDEDSDHEDKDRGRCAPAS-SSVPAEAELAGEGISVNTGPKGVINDWRRF 69
E+ +Y YS SE+ED H ++ P+S +VP E+ L E + + K ++
Sbjct: 317 EETEYEYSGSEEEDDSHGEEGE----PSSIMNVPGESTLRREFLRLQQENKSNSEALKQQ 372
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEE---EEQQKQKDLQEKISGKMTLKEFAI 126
+QL+ +Q+ + ++ L+ + +E EEQQ+++ Q K+ K +
Sbjct: 373 QQLQQQQQRDPEAHIKHLLHQRQRRIEEQKEERRRVEEQQRREREQRKLQEKEQQRRLED 432
Query: 127 M-----NEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKSI 181
M E++ E Q+Y+++++EE RQ Q +Q +L + ++Q+
Sbjct: 433 MQALRREEERRQAEREQEYKRKQLEEQRQSERLQRQLQQ------EHAYLKSLQQQQQQQ 486
Query: 182 VIMVHIYEDGIPG 194
+ + +PG
Sbjct: 487 QLQKQQQQQLLPG 499
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/162 (27%), Positives = 81/162 (50%), Gaps = 14/162 (8%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ E+ D G P+S ++P E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEE---EENDSGE--PSSILNLPGESTLRRDFLRLQLANKERS 365
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMT-----CRSHLDEEEEQQKQKDLQEKISGK 118
RR +QLE +QRE + + + L ++ R L+E++ ++K+ Q++ +
Sbjct: 366 EALRR-QQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQ 160
+E E++ E Q+Y+++++EE RQ Q KQ
Sbjct: 425 RHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQ 466
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/162 (27%), Positives = 81/162 (50%), Gaps = 14/162 (8%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ E+ D G P+S ++P E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEE---EENDSGE--PSSILNLPGESTLRRDFLRLQLANKERS 365
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMT-----CRSHLDEEEEQQKQKDLQEKISGK 118
RR +QLE +QRE + + + L ++ R L+E++ ++K+ Q++ +
Sbjct: 366 EALRR-QQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQ 160
+E E++ E Q+Y+++++EE RQ Q KQ
Sbjct: 425 RHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQ 466
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/162 (27%), Positives = 81/162 (50%), Gaps = 14/162 (8%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ E+ D G P+S ++P E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEE---EENDSGE--PSSILNLPGESTLRRDFLRLQLANKERS 365
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMT-----CRSHLDEEEEQQKQKDLQEKISGK 118
RR +QLE +QRE + + + L ++ R L+E++ ++K+ Q++ +
Sbjct: 366 EALRR-QQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQ 160
+E E++ E Q+Y+++++EE RQ Q KQ
Sbjct: 425 RHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQ 466
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/162 (27%), Positives = 81/162 (50%), Gaps = 14/162 (8%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ E+ D G P+S ++P E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEE---EENDSGE--PSSILNLPGESTLRRDFLRLQLANKERS 365
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMT-----CRSHLDEEEEQQKQKDLQEKISGK 118
RR +QLE +QRE + + + L ++ R L+E++ ++K+ Q++ +
Sbjct: 366 EALRR-QQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQ 160
+E E++ E Q+Y+++++EE RQ Q KQ
Sbjct: 425 RHYEEQMRREEERRRAEHEQEYKRKQLEEQRQAERLQRQLKQ 466
>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
sapiens]
Length = 1297
Score = 45.8 bits (107), Expect = 5e-05
Identities = 42/154 (27%), Positives = 79/154 (51%), Gaps = 14/154 (9%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ E+ D G P+S ++P E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEE---EENDSGE--PSSILNLPGESTLRRDFLRLQLANKERS 365
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMT-----CRSHLDEEEEQQKQKDLQEKISGK 118
RR +QLE +QRE + + + L ++ R L+E++ ++K+ Q++ +
Sbjct: 366 EALRR-QQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQL 152
+E E++ E Q+Y ++++EE ++QL
Sbjct: 425 RHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQL 458
>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
sapiens]
Length = 1305
Score = 45.8 bits (107), Expect = 5e-05
Identities = 42/154 (27%), Positives = 79/154 (51%), Gaps = 14/154 (9%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ E+ D G P+S ++P E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEE---EENDSGE--PSSILNLPGESTLRRDFLRLQLANKERS 365
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMT-----CRSHLDEEEEQQKQKDLQEKISGK 118
RR +QLE +QRE + + + L ++ R L+E++ ++K+ Q++ +
Sbjct: 366 EALRR-QQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQL 152
+E E++ E Q+Y ++++EE ++QL
Sbjct: 425 RHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQL 458
>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
sapiens]
Length = 1352
Score = 45.8 bits (107), Expect = 5e-05
Identities = 42/154 (27%), Positives = 79/154 (51%), Gaps = 14/154 (9%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ E+ D G P+S ++P E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEE---EENDSGE--PSSILNLPGESTLRRDFLRLQLANKERS 365
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMT-----CRSHLDEEEEQQKQKDLQEKISGK 118
RR +QLE +QRE + + + L ++ R L+E++ ++K+ Q++ +
Sbjct: 366 EALRR-QQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQL 152
+E E++ E Q+Y ++++EE ++QL
Sbjct: 425 RHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQL 458
>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
sapiens]
Length = 1360
Score = 45.8 bits (107), Expect = 5e-05
Identities = 42/154 (27%), Positives = 79/154 (51%), Gaps = 14/154 (9%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ E+ D G P+S ++P E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEE---EENDSGE--PSSILNLPGESTLRRDFLRLQLANKERS 365
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMT-----CRSHLDEEEEQQKQKDLQEKISGK 118
RR +QLE +QRE + + + L ++ R L+E++ ++K+ Q++ +
Sbjct: 366 EALRR-QQLEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQR 424
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQL 152
+E E++ E Q+Y ++++EE ++QL
Sbjct: 425 RHYEEQMRREEERRRAEHEQEYIRRQLEEEQRQL 458
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 42.0 bits (97), Expect = 7e-04
Identities = 28/99 (28%), Positives = 54/99 (54%), Gaps = 6/99 (6%)
Query: 68 RFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIM 127
R ++ E EQ++++ R ++L +K R +E EQQ++++ QE+ + +E
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346
Query: 128 NE-----DQDDEEFLQQYRKQRMEEMR-QQLHKGPQFKQ 160
E +Q++E QQ R+++ EE R QQL + Q ++
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385
Score = 39.3 bits (90), Expect = 0.004
Identities = 31/110 (28%), Positives = 60/110 (54%), Gaps = 6/110 (5%)
Query: 66 WRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQ-KDLQEKISGKMTLKEF 124
+R +QL E+ E+Q R +R K + L+E+E++ +Q +D Q + + +E
Sbjct: 1797 FREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEK 1856
Query: 125 AIMNED---QDDEEFLQQYRKQRMEE--MRQQLHKGPQFKQVFEISSGEG 169
+ E Q++E+ +Q R++++ E +R+Q + + +QV EI S EG
Sbjct: 1857 SRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEG 1906
Score = 38.9 bits (89), Expect = 0.006
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 3/84 (3%)
Query: 71 QLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNED 130
Q E QR+ + +E E ++KL +EEEQQ+Q+ +E+ ++ K+ E
Sbjct: 261 QEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ---QLRRKQEEERREQ 317
Query: 131 QDDEEFLQQYRKQRMEEMRQQLHK 154
Q++ Q+ R+Q+ E QQL +
Sbjct: 318 QEERREQQERREQQEERREQQLRR 341
Score = 38.5 bits (88), Expect = 0.007
Identities = 24/82 (29%), Positives = 43/82 (52%), Gaps = 11/82 (13%)
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNE 129
+Q E ++ EEQ R++ER R EEE+QQ++ ++++ K +
Sbjct: 267 RQRELQEEEEQLRKLER------QELRRERQEEEQQQQRLRREQQLRRKQEEE-----RR 315
Query: 130 DQDDEEFLQQYRKQRMEEMRQQ 151
+Q +E QQ R+++ EE R+Q
Sbjct: 316 EQQEERREQQERREQQEERREQ 337
Score = 37.4 bits (85), Expect = 0.016
Identities = 22/77 (28%), Positives = 45/77 (58%), Gaps = 7/77 (9%)
Query: 75 EQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQDDE 134
E+ E++ R+ E +++K +EEE Q+Q++LQE+ L+ + E Q++E
Sbjct: 240 EEEEKEWRKRETVLRK-----EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEE 294
Query: 135 EFLQQYRKQRMEEMRQQ 151
+ QQ R +R +++R++
Sbjct: 295 Q--QQQRLRREQQLRRK 309
Score = 37.0 bits (84), Expect = 0.021
Identities = 29/110 (26%), Positives = 55/110 (50%), Gaps = 5/110 (4%)
Query: 73 ETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQD 132
E +Q EEQ ER ++ R + +EEE QQ+++ L + K +E +
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE---LERQYR 1171
Query: 133 DEEFLQQYRKQ--RMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQKS 180
+EE LQQ +Q R E+ +++ + Q+++ E+ + D++Q+S
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS 1221
Score = 36.2 bits (82), Expect = 0.036
Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 8/104 (7%)
Query: 65 DWRRF--KQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDL--QEKISGKMT 120
+W R K+ E +Q EEQ ER ++L R + +EEE QQ+++ L +E+ + +
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQ 1074
Query: 121 LKEFAIMNED---QDDEEFL-QQYRKQRMEEMRQQLHKGPQFKQ 160
E E+ Q++E+ L ++ K+R +E +Q + + +Q
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Score = 36.2 bits (82), Expect = 0.036
Identities = 27/98 (27%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 73 ETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDL--QEKISGKMTLKEFAIMNED 130
E +Q EEQ ER ++ R + EEE QQ+++ L +E + +E E+
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEE 1114
Query: 131 QDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGE 168
+ +E Q R++R + RQ+L + Q+++ E+ E
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELER--QYREEEEVQQEE 1150
Score = 35.8 bits (81), Expect = 0.048
Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 15/118 (12%)
Query: 67 RRFKQLETEQ---REEQCREMERLIKKLSMTCRSHL--DEEEEQQKQKDLQEKISGKMTL 121
RR +QL EQ RE+Q R ++L ++ + L ++EEE+ +QK QE+
Sbjct: 390 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER------- 442
Query: 122 KEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQK 179
+E + E ++ ++L +++ E +Q + Q K+ E E +L + ++E++
Sbjct: 443 REQRLKREQEERRDWL---KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERR 497
Score = 35.8 bits (81), Expect = 0.048
Identities = 35/159 (22%), Positives = 70/159 (44%), Gaps = 14/159 (8%)
Query: 4 LDDKLLGEKLQYYYSSSEDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTGPKGVI 63
L D+ + LQ+ ++ D + E R R P E +L E K
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQE---RRRWQQRDRHFPEEEQLEREE---QKEAKRRD 1311
Query: 64 NDWRRFKQLETEQREEQCR--EMERLIKKLSMTCRSHLD------EEEEQQKQKDLQEKI 115
+ KQL E+REE+ R E +R ++ + + E + + ++++L+ +
Sbjct: 1312 RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQE 1371
Query: 116 SGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHK 154
G+ L+E + + + +FL++ ++ R +E QQL +
Sbjct: 1372 QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410
Score = 34.3 bits (77), Expect = 0.14
Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 7/88 (7%)
Query: 73 ETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNEDQD 132
+ E+R EQ E+ ++ R +E EQQ +++ +E+ + + +Q+
Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE-------RREQQLRREQE 369
Query: 133 DEEFLQQYRKQRMEEMRQQLHKGPQFKQ 160
+E QQ R+++ QQL + Q ++
Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRR 397
Score = 34.3 bits (77), Expect = 0.14
Identities = 23/91 (25%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 67 RRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQ---EKISGKMTLKE 123
R+ +Q + Q E+Q R ER ++ R +EE+ +Q++++ Q ++ K L+E
Sbjct: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 124 FAIMNEDQDDEEFLQQYRKQRMEEMRQQLHK 154
+ ++Q + +F++ ++ R +E +QQL +
Sbjct: 1586 QKVRRQEQ-ERKFMEDEQQLRRQEGQQQLRQ 1615
Score = 33.9 bits (76), Expect = 0.18
Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNE 129
++ + E+RE+Q R E+ ++ R +E EQQ +++ +E+ + +E + E
Sbjct: 328 REQQEERREQQLRR-EQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 130 DQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQ 160
Q E QQ R+++ QQL + Q ++
Sbjct: 387 QQLRRE--QQLRREQQLRREQQLRREQQLRR 415
Score = 33.9 bits (76), Expect = 0.18
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 67 RRFKQLETEQ---REEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKE 123
RR +QL EQ RE+Q R + ++ R +E EQQ +++ Q + ++ +E
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR-RE 392
Query: 124 FAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQK 179
+ E Q E QQ R+++ QQL + Q ++ E E + +EQ+
Sbjct: 393 QQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQR 446
Score = 33.9 bits (76), Expect = 0.18
Identities = 26/94 (27%), Positives = 52/94 (55%), Gaps = 17/94 (18%)
Query: 70 KQLETEQRE-----EQCREMERLIKKLSMTCRSHLDEEEEQQK-QKDLQEKISGKMTLKE 123
K+LE E+RE EQ ++L+K+ +EE QQ+ +++ +E++ ++ +E
Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKR---------EEERRQQRLKREQEERLEQRLKREE 606
Query: 124 FAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQ 157
+ +++ E+ L+ R++ EE RQQL K +
Sbjct: 607 VERLEQEERREQRLK--REEPEEERRQQLLKSEE 638
Score = 33.5 bits (75), Expect = 0.24
Identities = 27/105 (25%), Positives = 54/105 (51%), Gaps = 6/105 (5%)
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDL----QEKISGKMTLKEFA 125
K + +Q+EEQ E ++ + + +EEE QQ+++ L +EK + +++
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 126 IMNEDQDDEEFL--QQYRKQRMEEMRQQLHKGPQFKQVFEISSGE 168
+E Q +EE L ++ K+R++E +Q + + +Q E GE
Sbjct: 1022 KKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGE 1066
Score = 33.1 bits (74), Expect = 0.31
Identities = 20/85 (23%), Positives = 47/85 (55%), Gaps = 7/85 (8%)
Query: 67 RRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAI 126
R K E E+RE+Q R ++L ++ L +EE+++ LQ+++ + L+
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEER---LQQRLRSEQQLRR--- 540
Query: 127 MNEDQDDEEFLQQYRKQRMEEMRQQ 151
+++ E+ L++ ++R+E+ R++
Sbjct: 541 -EQEERREQLLKREEEKRLEQERRE 564
Score = 32.7 bits (73), Expect = 0.40
Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 6/97 (6%)
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDL----QEKISGKMTLKEFA 125
K+ E +Q EEQ E ++ R +EEE QQ+++ L +EK + +++
Sbjct: 1082 KEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYR 1141
Query: 126 IMNEDQDDEEFL--QQYRKQRMEEMRQQLHKGPQFKQ 160
E Q +EE L ++ K+R +E+ +Q + + +Q
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178
Score = 32.3 bits (72), Expect = 0.53
Identities = 24/94 (25%), Positives = 50/94 (53%), Gaps = 6/94 (6%)
Query: 73 ETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDL--QEKISGKMTLKEFAIMNED 130
E +Q EEQ ER ++ R + ++E QQ+++ L +E+ ++ +E E+
Sbjct: 995 ELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEE 1054
Query: 131 ---QDDEEFLQQYRK-QRMEEMRQQLHKGPQFKQ 160
Q++E+ L + R+ +R +E+ +Q K + +Q
Sbjct: 1055 ELQQEEEQLLGEERETRRRQELERQYRKEEELQQ 1088
Score = 32.0 bits (71), Expect = 0.69
Identities = 30/122 (24%), Positives = 58/122 (47%), Gaps = 7/122 (5%)
Query: 67 RRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEK---ISGKMTLKE 123
RR +Q + EEQ ++ E + + R + E + +K K LQ+K + G+ K
Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKR 981
Query: 124 FAIMNEDQ-DDEEFLQQYRKQRMEEMRQQLHKGP---QFKQVFEISSGEGFLDMIDKEQK 179
E + +EE LQQ +Q + E R++ + Q+++ E+ E L ++E++
Sbjct: 982 RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKR 1041
Query: 180 SI 181
+
Sbjct: 1042 RL 1043
Score = 31.6 bits (70), Expect = 0.90
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEEEE-------QQKQKDLQEKISGKMTLK 122
++ E +RE R+ E +++ + L EEEE Q+ +++ QE+ + L+
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
Query: 123 EFAIMNEDQDDEEFLQQYRKQRMEEMRQQ 151
+ Q++E QQ ++ +E R+Q
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQ 330
Score = 31.6 bits (70), Expect = 0.90
Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 14/96 (14%)
Query: 67 RRFKQLETEQRE------EQCREMERLIKKLSMTCRSHLDEEEEQ----QKQKDLQEKIS 116
RR +QL EQ+E ++ E ERL ++L R H +E EQ ++Q+ +E+I
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLK---REHEEERREQELAEEEQEQARERIK 698
Query: 117 GKMTLKEFAIMNE-DQDDEEFLQQYRKQRMEEMRQQ 151
++ ++ + +E D + + RKQ + RQ+
Sbjct: 699 SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734
Score = 31.6 bits (70), Expect = 0.90
Identities = 33/148 (22%), Positives = 61/148 (41%), Gaps = 17/148 (11%)
Query: 21 EDEDSDHEDKDRGRCAPASSSVPAEAELAGEGISVNTG--PKGVINDWRRFKQLETEQRE 78
E+ED ED++R R +L E K + + R +Q ++ E
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 79 EQCREMERLIKKLSMTCRSHLDEEEEQQKQKDL---------------QEKISGKMTLKE 123
E+ + ER ++ R + +EE+ QQ+++ L Q + K+ KE
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 124 FAIMNEDQDDEEFLQQYRKQRMEEMRQQ 151
++ E+ + ++ +K R EE QQ
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQ 998
Score = 31.2 bits (69), Expect = 1.2
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 7/94 (7%)
Query: 68 RFKQLETEQREEQCREMERLIKKLSMTCRSHL---DEEEE--QQKQKDLQEKISGKMTLK 122
R+ +LE E+R EQ E+ +++ R EEEE QQ+ + Q+ + +
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 123 EFAIMNEDQD--DEEFLQQYRKQRMEEMRQQLHK 154
E + E++ ++E +Q K+ EE R QL K
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLK 580
Score = 30.8 bits (68), Expect = 1.5
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 18/104 (17%)
Query: 67 RRFKQLETEQREE---QCREMERLIKKLSMT-------------CRSHLDEEEEQQKQKD 110
RR +QL EQ EE Q E ER ++L H E +QQ ++D
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 111 LQEKISGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHK 154
+E+ + E E Q+ E QQ R+++ E Q+L +
Sbjct: 480 QEEERRERWLKLEEEERREQQERRE--QQLRREQEERREQRLKR 521
Score = 30.8 bits (68), Expect = 1.5
Identities = 21/96 (21%), Positives = 51/96 (53%), Gaps = 11/96 (11%)
Query: 67 RRFKQLETEQREEQCR--EMERLIKKLSMTCRSHLDEEEEQQKQKDL---------QEKI 115
+R K+ + E+ E++ + E+ERL ++ R +E EE+++Q+ L Q+++
Sbjct: 588 QRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL 647
Query: 116 SGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQ 151
+ + + ++++E Q+ +++ EE R+Q
Sbjct: 648 RREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Score = 30.8 bits (68), Expect = 1.5
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 67 RRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKD--LQEKISGKMTLKEF 124
R++++ E Q+EE+ E K+ EEEE Q++++ L+E+ + +E
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERE- 1196
Query: 125 AIMNEDQDDEEFLQQYRKQRMEEMRQQ 151
+ +++EE +Q RKQR + Q+
Sbjct: 1197 ---RQYREEEELQRQKRKQRYRDEDQR 1220
Score = 30.4 bits (67), Expect = 2.0
Identities = 27/121 (22%), Positives = 57/121 (47%), Gaps = 8/121 (6%)
Query: 67 RRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAI 126
RR ++ EQR ++ E ERL ++L + ++EE +++ +E+ + +E +
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRL 567
Query: 127 MNEDQD--------DEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQ 178
E ++ +EE QQ K+ EE +Q K + +++ + E L + E+
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627
Query: 179 K 179
+
Sbjct: 628 E 628
Score = 29.6 bits (65), Expect = 3.4
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 67 RRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAI 126
RR ++ + EE+ R L K ++ + +++ Q+++++LQ + K +E
Sbjct: 869 RRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQER 928
Query: 127 MNED-----QDDEEFLQQYR-KQRMEEMRQQLHKGPQFKQVFEISSGE 168
+ Q++E+ L++ R K+R +E +Q K + +Q E GE
Sbjct: 929 QYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976
Score = 29.6 bits (65), Expect = 3.4
Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 19/111 (17%)
Query: 66 WRRFKQLETEQREEQCREMERLIK--------------KLSMTCRSHLDEEEEQQKQKDL 111
+R +QL E +EQ R ER K +L R EEEQ +Q+
Sbjct: 1725 FREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 112 QEKISGKMTLKEF---AIMNEDQDDEEFLQQYR--KQRMEEMRQQLHKGPQ 157
++++ + + ++F + +++++++ Q R K R EE + QL + Q
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835
Score = 29.3 bits (64), Expect = 4.4
Identities = 21/90 (23%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 66 WRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQ-KDLQEKISGKMTLKEF 124
+R +QL E+ E+Q ER R L+EE + ++Q ++ Q + +E
Sbjct: 1621 FREDEQLLQEREEQQLHRQER--------DRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 125 AIMNEDQDDEEFLQQYRKQRMEEMRQQLHK 154
+ ++ ++++ +Q R ++ E QQL +
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Score = 28.9 bits (63), Expect = 5.8
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 20/96 (20%)
Query: 66 WRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQK----------QKDLQEKI 115
+R +QL E+ E+Q ER K L EEEQQ +++L+ +
Sbjct: 1463 FREEEQLLQEREEQQLHRQERDRKFL----------EEEQQLRRQERDRKFREQELRSQE 1512
Query: 116 SGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQ 151
+ L+E ++ Q +FLQ+ ++ R +E QQ
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Score = 28.1 bits (61), Expect = 9.9
Identities = 25/110 (22%), Positives = 56/110 (50%), Gaps = 6/110 (5%)
Query: 70 KQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKEFAIMNE 129
+QL ++RE + + E+ +++ + + EEEQ +Q+ QE++ + ++ I+ E
Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFR---EEEQLRQETEQEQLRRQERYRK--ILEE 1752
Query: 130 DQ-DDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQ 178
+Q E QQ R+Q + ++ + Q ++ ++ S E ++EQ
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
>gi|94680976 coiled-coil domain containing 112 isoform 1 [Homo
sapiens]
Length = 529
Score = 42.0 bits (97), Expect = 7e-04
Identities = 27/121 (22%), Positives = 65/121 (53%), Gaps = 11/121 (9%)
Query: 70 KQLETEQREEQCREMERLIKK---------LSMTCRSHLDEEEEQQK--QKDLQEKISGK 118
KQ + ++++E+ R+ ++L + +SM C S L EEEE++K QK+ Q + K
Sbjct: 339 KQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLK 398
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQ 178
+ L+ + ++Q++ L++ +++ E+ ++ + + + E + L ++D++
Sbjct: 399 LLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQA 458
Query: 179 K 179
K
Sbjct: 459 K 459
>gi|145580595 coiled-coil domain containing 112 isoform 2 [Homo
sapiens]
Length = 446
Score = 42.0 bits (97), Expect = 7e-04
Identities = 27/121 (22%), Positives = 65/121 (53%), Gaps = 11/121 (9%)
Query: 70 KQLETEQREEQCREMERLIKK---------LSMTCRSHLDEEEEQQK--QKDLQEKISGK 118
KQ + ++++E+ R+ ++L + +SM C S L EEEE++K QK+ Q + K
Sbjct: 256 KQEDNQKQKEEQRKKQKLAVEAWKKQKSIEMSMKCASQLKEEEEKEKKHQKERQRQFKLK 315
Query: 119 MTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFEISSGEGFLDMIDKEQ 178
+ L+ + ++Q++ L++ +++ E+ ++ + + + E + L ++D++
Sbjct: 316 LLLESYTQQKKEQEEFLRLEKEIREKAEKAEKRKNAADEISRFQERDLHKLELKILDRQA 375
Query: 179 K 179
K
Sbjct: 376 K 376
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 41.6 bits (96), Expect = 9e-04
Identities = 35/148 (23%), Positives = 76/148 (51%), Gaps = 17/148 (11%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ + +++ P+S +VP E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEEEEVPEQEG---EPSSIVNVPGESTLRRDFLRLQQENKERS 367
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKE 123
RR + L+ E+Q RE E ++L + +++++EQ+++ + Q++ +E
Sbjct: 368 EALRRQQLLQ----EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR-------RE 416
Query: 124 FAIMNEDQDDEEFLQQYRKQRMEEMRQQ 151
+ + ++ +Q K+R+EE+ ++
Sbjct: 417 REARRQQEREQRRREQEEKRRLEELERR 444
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 41.6 bits (96), Expect = 9e-04
Identities = 35/148 (23%), Positives = 76/148 (51%), Gaps = 17/148 (11%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ + +++ P+S +VP E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEEEEVPEQEG---EPSSIVNVPGESTLRRDFLRLQQENKERS 367
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKE 123
RR + L+ E+Q RE E ++L + +++++EQ+++ + Q++ +E
Sbjct: 368 EALRRQQLLQ----EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR-------RE 416
Query: 124 FAIMNEDQDDEEFLQQYRKQRMEEMRQQ 151
+ + ++ +Q K+R+EE+ ++
Sbjct: 417 REARRQQEREQRRREQEEKRRLEELERR 444
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 41.6 bits (96), Expect = 9e-04
Identities = 35/148 (23%), Positives = 76/148 (51%), Gaps = 17/148 (11%)
Query: 7 KLLGEK--LQYYYSSSEDEDSDHEDKDRGRCAPASS-SVPAEAELAGEGISVNTGPKGVI 63
K GEK +Y YS SE+E+ + +++ P+S +VP E+ L + + + K
Sbjct: 311 KKRGEKDETEYEYSGSEEEEEEVPEQEG---EPSSIVNVPGESTLRRDFLRLQQENKERS 367
Query: 64 NDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLKE 123
RR + L+ E+Q RE E ++L + +++++EQ+++ + Q++ +E
Sbjct: 368 EALRRQQLLQ----EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQR-------RE 416
Query: 124 FAIMNEDQDDEEFLQQYRKQRMEEMRQQ 151
+ + ++ +Q K+R+EE+ ++
Sbjct: 417 REARRQQEREQRRREQEEKRRLEELERR 444
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 38.9 bits (89), Expect = 0.006
Identities = 28/99 (28%), Positives = 58/99 (58%), Gaps = 9/99 (9%)
Query: 68 RFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQ--KDLQEKISGKMTLKEFA 125
R +QL+ E++E + +E+E L+++ L EEEE+++ ++LQ+ + G++ E A
Sbjct: 349 RLQQLQ-EEKERKLQELE-LLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQA 406
Query: 126 IMN-----EDQDDEEFLQQYRKQRMEEMRQQLHKGPQFK 159
+ E +++E Q+ R + +EEM+Q+L + Q +
Sbjct: 407 RASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLE 445
>gi|213688415 coiled-coil domain containing 66 isoform 1 [Homo
sapiens]
Length = 948
Score = 38.9 bits (89), Expect = 0.006
Identities = 30/92 (32%), Positives = 51/92 (55%), Gaps = 7/92 (7%)
Query: 63 INDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLK 122
+ + RR KQLE EQR+++ +E E + + + +E+ +QKQK E+I MTLK
Sbjct: 475 VEEKRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQK---EEI---MTLK 528
Query: 123 EFAIMNEDQDDEEFLQQYR-KQRMEEMRQQLH 153
+ Q +E Q+ + +QR+ E+ Q+ H
Sbjct: 529 TNELFQTMQRAQELAQRLKQEQRIRELAQKGH 560
>gi|213688413 coiled-coil domain containing 66 isoform 2 [Homo
sapiens]
Length = 914
Score = 38.9 bits (89), Expect = 0.006
Identities = 30/92 (32%), Positives = 51/92 (55%), Gaps = 7/92 (7%)
Query: 63 INDWRRFKQLETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQKQKDLQEKISGKMTLK 122
+ + RR KQLE EQR+++ +E E + + + +E+ +QKQK E+I MTLK
Sbjct: 441 VEEKRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQK---EEI---MTLK 494
Query: 123 EFAIMNEDQDDEEFLQQYR-KQRMEEMRQQLH 153
+ Q +E Q+ + +QR+ E+ Q+ H
Sbjct: 495 TNELFQTMQRAQELAQRLKQEQRIRELAQKGH 526
>gi|95113651 glutaredoxin 3 [Homo sapiens]
Length = 335
Score = 38.1 bits (87), Expect = 0.010
Identities = 25/86 (29%), Positives = 44/86 (51%), Gaps = 2/86 (2%)
Query: 161 VFEISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKS- 219
V E+ S F +++ + KS+++ VH + P MN M LA E P V F K+++
Sbjct: 13 VEEVGSAGQFEELLRLKAKSLLV-VHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAE 71
Query: 220 SVIGASSQFTRNALPALLIYKGGELI 245
V S ++ +++P L +K + I
Sbjct: 72 GVPEVSEKYEISSVPTFLFFKNSQKI 97
>gi|171460958 nucleolar protein 10 [Homo sapiens]
Length = 688
Score = 38.1 bits (87), Expect = 0.010
Identities = 37/142 (26%), Positives = 71/142 (50%), Gaps = 17/142 (11%)
Query: 73 ETEQREEQCREMERLIKKLSMTCRSHLDEEEEQQ-KQKDLQEKISGKMTLKEFAIMNEDQ 131
+ ++ E+ R + L+ K+S + L E+Q+ ++K+ +E+ GK + E +E
Sbjct: 495 QVDEESEEFRLLNPLVSKISEKRKKKLRLLEQQELREKEEEEEPEGKPSDAE---SSESS 551
Query: 132 DDEE-FLQQYRKQR-MEEMRQQLHKGPQFK---------QVFEISSGEGFLDMIDKEQKS 180
DDE+ ++++ RKQR + + +++ + + K Q +EI +GE F D K
Sbjct: 552 DDEKAWVEEVRKQRRLLQQEEKVKRQERLKEDQQTVLKPQFYEIKAGEEFRSFKDSATKQ 611
Query: 181 IVIMVHIYEDGIPGTEAMNGCM 202
+M ED + EA NG +
Sbjct: 612 -KLMNKTLEDRLK-IEAKNGTL 631
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 38.1 bits (87), Expect = 0.010
Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 10/93 (10%)
Query: 70 KQLETEQREEQCREMERLIKKLS----------MTCRSHLDEEEEQQKQKDLQEKISGKM 119
K+LE E+ E+Q ++ + KK + + RS D +EE++ ++++ SGK+
Sbjct: 249 KKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKV 308
Query: 120 TLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQL 152
T + E+ D E ++ ++ +M + + L
Sbjct: 309 TRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKML 341
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 38.1 bits (87), Expect = 0.010
Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 10/93 (10%)
Query: 70 KQLETEQREEQCREMERLIKKLS----------MTCRSHLDEEEEQQKQKDLQEKISGKM 119
K+LE E+ E+Q ++ + KK + + RS D +EE++ ++++ SGK+
Sbjct: 249 KKLEKERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTENVEAASSGKV 308
Query: 120 TLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQL 152
T + E+ D E ++ ++ +M + + L
Sbjct: 309 TRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKML 341
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,478,361
Number of Sequences: 37866
Number of extensions: 540382
Number of successful extensions: 4352
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 99
Number of HSP's successfully gapped in prelim test: 279
Number of HSP's that attempted gapping in prelim test: 3079
Number of HSP's gapped (non-prelim): 1152
length of query: 301
length of database: 18,247,518
effective HSP length: 102
effective length of query: 199
effective length of database: 14,385,186
effective search space: 2862652014
effective search space used: 2862652014
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.