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Search of human proteins with 82659087
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82659087 staufen isoform b [Homo sapiens]
(577 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82659087 staufen isoform b [Homo sapiens] 1148 0.0
gi|82659089 staufen isoform a [Homo sapiens] 999 0.0
gi|82659085 staufen isoform a [Homo sapiens] 999 0.0
gi|82659083 staufen isoform a [Homo sapiens] 999 0.0
gi|82659091 staufen isoform c [Homo sapiens] 992 0.0
gi|7657625 staufen homolog 2 [Homo sapiens] 395 e-110
gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens] 79 1e-14
gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens] 79 1e-14
gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens] 79 1e-14
gi|213417919 protein kinase, interferon-inducible double strande... 74 4e-13
gi|213417911 protein kinase, interferon-inducible double strande... 74 4e-13
gi|4505581 protein kinase, interferon-inducible double stranded ... 74 4e-13
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom... 60 4e-09
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom... 60 4e-09
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 60 4e-09
gi|212549555 interleukin enhancer binding factor 3 isoform e [Ho... 60 5e-09
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 60 5e-09
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo... 60 7e-09
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s... 60 7e-09
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s... 60 7e-09
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s... 60 7e-09
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa... 56 8e-08
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa... 56 8e-08
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa... 56 8e-08
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa... 56 8e-08
gi|21361745 spermatid perinuclear RNA binding protein [Homo sapi... 56 1e-07
gi|208431829 eukaryotic translation initiation factor 2-alpha ki... 46 8e-05
gi|208431827 eukaryotic translation initiation factor 2-alpha ki... 46 8e-05
gi|4506103 eukaryotic translation initiation factor 2-alpha kina... 46 8e-05
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens] 44 5e-04
>gi|82659087 staufen isoform b [Homo sapiens]
Length = 577
Score = 1148 bits (2969), Expect = 0.0
Identities = 577/577 (100%), Positives = 577/577 (100%)
Query: 1 MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSAS 60
MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSAS
Sbjct: 1 MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSAS 60
Query: 61 ITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPF 120
ITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPF
Sbjct: 61 ITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPF 120
Query: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 180
PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN
Sbjct: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 180
Query: 181 LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKN 240
LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKN
Sbjct: 181 LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKN 240
Query: 241 AAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKE 300
AAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKE
Sbjct: 241 AAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKE 300
Query: 301 KEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQ 360
KEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQ
Sbjct: 301 KEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQ 360
Query: 361 PTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPM 420
PTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPM
Sbjct: 361 PTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPM 420
Query: 421 VPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGH 480
VPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGH
Sbjct: 421 VPEVAQAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGH 480
Query: 481 VPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVES 540
VPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVES
Sbjct: 481 VPHGPLTRPSEQLDYLSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVES 540
Query: 541 CHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC 577
CHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC
Sbjct: 541 CHDMAALNILKLLSELDQQSTEMPRTGNGPMSVCGRC 577
>gi|82659089 staufen isoform a [Homo sapiens]
Length = 496
Score = 999 bits (2582), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 82 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 141
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 142 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 201
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
Query: 202 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 261
FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV
Sbjct: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
Query: 262 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 321
KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM
Sbjct: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
Query: 322 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 381
QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR
Sbjct: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
Query: 382 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 441
KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR
Sbjct: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
Query: 442 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 501
AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG
Sbjct: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
Query: 502 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 561
FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST
Sbjct: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
Query: 562 EMPRTGNGPMSVCGRC 577
EMPRTGNGPMSVCGRC
Sbjct: 481 EMPRTGNGPMSVCGRC 496
>gi|82659085 staufen isoform a [Homo sapiens]
Length = 496
Score = 999 bits (2582), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 82 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 141
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 142 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 201
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
Query: 202 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 261
FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV
Sbjct: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
Query: 262 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 321
KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM
Sbjct: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
Query: 322 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 381
QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR
Sbjct: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
Query: 382 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 441
KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR
Sbjct: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
Query: 442 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 501
AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG
Sbjct: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
Query: 502 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 561
FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST
Sbjct: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
Query: 562 EMPRTGNGPMSVCGRC 577
EMPRTGNGPMSVCGRC
Sbjct: 481 EMPRTGNGPMSVCGRC 496
>gi|82659083 staufen isoform a [Homo sapiens]
Length = 496
Score = 999 bits (2582), Expect = 0.0
Identities = 496/496 (100%), Positives = 496/496 (100%)
Query: 82 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 141
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 142 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 201
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
Query: 202 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 261
FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV
Sbjct: 121 FEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERV 180
Query: 262 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 321
KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM
Sbjct: 181 KPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVM 240
Query: 322 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 381
QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR
Sbjct: 241 QVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIKKPGDGR 300
Query: 382 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 441
KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR
Sbjct: 301 KVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHHTKDFTR 360
Query: 442 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 501
AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG
Sbjct: 361 AAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDYLSRVQG 420
Query: 502 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 561
FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST
Sbjct: 421 FQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSELDQQST 480
Query: 562 EMPRTGNGPMSVCGRC 577
EMPRTGNGPMSVCGRC
Sbjct: 481 EMPRTGNGPMSVCGRC 496
>gi|82659091 staufen isoform c [Homo sapiens]
Length = 502
Score = 992 bits (2565), Expect = 0.0
Identities = 496/502 (98%), Positives = 496/502 (98%), Gaps = 6/502 (1%)
Query: 82 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 141
MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK
Sbjct: 1 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGK 60
Query: 142 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 201
GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN
Sbjct: 61 GKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEENLNKSEISQVFEIALKRNLPVN 120
Query: 202 FE------VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 255
FE VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL
Sbjct: 121 FESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPL 180
Query: 256 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 315
PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR
Sbjct: 181 PAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPR 240
Query: 316 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 375
RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK
Sbjct: 241 RREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPALKSEEKTPIK 300
Query: 376 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 435
KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH
Sbjct: 301 KPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAGILPMVPEVAQAVGVSQGHH 360
Query: 436 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 495
TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY
Sbjct: 361 TKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRPSEQLDY 420
Query: 496 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 555
LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE
Sbjct: 421 LSRVQGFQVEYKDFPKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAALNILKLLSE 480
Query: 556 LDQQSTEMPRTGNGPMSVCGRC 577
LDQQSTEMPRTGNGPMSVCGRC
Sbjct: 481 LDQQSTEMPRTGNGPMSVCGRC 502
>gi|7657625 staufen homolog 2 [Homo sapiens]
Length = 479
Score = 395 bits (1016), Expect = e-110
Identities = 256/523 (48%), Positives = 322/523 (61%), Gaps = 69/523 (13%)
Query: 1 MSQVQVQVQNPSAALSGSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSAS 60
M VQ+ + + GS I Q++ ++ L T S+LP +P+Q P ++
Sbjct: 7 MFSVQLSLGEQTWESEGSSIKKAQQAVANKAL-----TESTLP-----KPVQKP--PKSN 54
Query: 61 ITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPF 120
+ + SITPTVELN L MK G+ +Y+P+DP NYN RG Y RY P
Sbjct: 55 VNNNPG---SITPTVELNGLAMKRGEPAIYRPLDPKPFPNYRANYNFRG-MYNQRYHCPV 110
Query: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRES---- 176
P ++ V+L+VG +F G+GKTRQAA+H+AA KAL+ LQNEP+PER NG
Sbjct: 111 PK---IFYVQLTVGNNEFFGEGKTRQAARHNAAMKALQALQNEPIPERSPQNGESGKDMD 167
Query: 177 EEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKI 236
++++ NKSEIS VFEIALKRN+PV+FEV +ESGPPHMK+FVT+VSVGEF EGEG SKK+
Sbjct: 168 DDKDANKSEISLVFEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKL 227
Query: 237 SKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQ 296
SKK AA VL+ELKKLPPLP VE+ K KK+ K IVK PEYGQG+NPISRLAQIQQ
Sbjct: 228 SKKRAATTVLQELKKLPPLPVVEKPKLFFKKRPKTIVK--AGPEYGQGMNPISRLAQIQQ 285
Query: 297 AKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKV 356
AKKEKEP+Y LL+ERG+PRRREFVMQVKVGN A GTG NKK+AK+NAAE ML LG+K
Sbjct: 286 AKKEKEPDYVLLSERGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQLGYKA 345
Query: 357 PQAQPTKPALKSEEKTPIKKPGDGRKVTFFEPGSGDENGTSNKEDEFRMPYLSHQQLPAG 416
+ EKT K G K F EP T+N P G
Sbjct: 346 -----STNLQDQLEKTGENKGWSGPKPGFPEP-------TNN--------------TPKG 379
Query: 417 ILPMVPEVAQAV---------GVSQGH-HTKDFTRAAPN----PAKATVTAMIARELLYG 462
IL + P+V Q + G + G+ KD + + + + +A IARELL
Sbjct: 380 ILHLSPDVYQEMEASRHKVISGTTLGYLSPKDMNQPSSSFFSISPTSNSSATIARELLMN 439
Query: 463 GTSPTAETI-LKNNISSGHVPHGPLTRPSEQLDYLSRVQGFQV 504
GTS TAE I LK SS P P+ +PS+QL+YL+R+QGFQV
Sbjct: 440 GTSSTAEAIGLKG--SSPTPPCSPV-QPSKQLEYLARIQGFQV 479
>gi|19743838 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 78.6 bits (192), Expect = 1e-14
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 180 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 239
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 5 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 64
Query: 240 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 272
AA L+ LK +P A P + ++ P+
Sbjct: 65 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 124
Query: 273 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 331
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 125 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 183
Query: 332 GTGTNKKVAKRNAAENML 349
G+GT+KK+AKRNAA ML
Sbjct: 184 GSGTSKKLAKRNAAAKML 201
Score = 50.8 bits (120), Expect = 3e-06
Identities = 55/229 (24%), Positives = 88/229 (38%), Gaps = 64/229 (27%)
Query: 66 AAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPL 125
AA TP L ++GK P+Y + G A+ P + +
Sbjct: 3 AANPGKTPISLLQEYGTRIGKTPVYDLL------------KAEGQAHQPNFTF------- 43
Query: 126 LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKS 184
++VG G+G +++AAKH AA AL+ L+ + E LE + S ++
Sbjct: 44 ----RVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE 99
Query: 185 EI---------SQVFEIALKRNLPVNFE-------------------------------V 204
+I + V + L R+ P+ + V
Sbjct: 100 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV 159
Query: 205 ARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
+ESGP H K F V F+ G G SKK++K+NAA +L + +P
Sbjct: 160 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 208
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 284 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 343
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 7 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 65
Query: 344 AAENMLEIL 352
AAE L+ L
Sbjct: 66 AAEVALKHL 74
>gi|19743840 TAR RNA binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 78.6 bits (192), Expect = 1e-14
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 180 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 239
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 26 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 85
Query: 240 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 272
AA L+ LK +P A P + ++ P+
Sbjct: 86 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 145
Query: 273 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 331
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 146 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 204
Query: 332 GTGTNKKVAKRNAAENML 349
G+GT+KK+AKRNAA ML
Sbjct: 205 GSGTSKKLAKRNAAAKML 222
Score = 52.4 bits (124), Expect = 1e-06
Identities = 57/235 (24%), Positives = 90/235 (38%), Gaps = 64/235 (27%)
Query: 60 SITSTSAAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYP 119
SI AA TP L ++GK P+Y + G A+ P + +
Sbjct: 18 SIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLL------------KAEGQAHQPNFTF- 64
Query: 120 FPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEE 178
++VG G+G +++AAKH AA AL+ L+ + E LE + S
Sbjct: 65 ----------RVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPL 114
Query: 179 ENLNKSEI---------SQVFEIALKRNLPVNFE-------------------------- 203
++ +I + V + L R+ P+ +
Sbjct: 115 DSSLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWR 174
Query: 204 -----VARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
V +ESGP H K F V F+ G G SKK++K+NAA +L + +P
Sbjct: 175 LPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 229
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 284 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 343
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 28 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 86
Query: 344 AAENMLEIL 352
AAE L+ L
Sbjct: 87 AAEVALKHL 95
>gi|85068512 TAR RNA binding protein 2 isoform b [Homo sapiens]
Length = 345
Score = 78.6 bits (192), Expect = 1e-14
Identities = 58/198 (29%), Positives = 90/198 (45%), Gaps = 29/198 (14%)
Query: 180 NLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKK 239
N K+ IS + E + +++ + G H NF +V+VG+ G+G SKK +K
Sbjct: 5 NPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKH 64
Query: 240 NAAIAVLEELK------------------------KLPPLPAVERVKPR---IKKKTKPI 272
AA L+ LK +P A P + ++ P+
Sbjct: 65 KAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPEDIPVFTAAAAATPVPSVVLTRSPPM 124
Query: 273 -VKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAE 331
++P SP+ + NP+ L ++ K + PEYT+ E G R+EF M +V
Sbjct: 125 ELQPPVSPQQSE-CNPVGALQELVVQKGWRLPEYTVTQESGPAHRKEFTMTCRVERFIEI 183
Query: 332 GTGTNKKVAKRNAAENML 349
G+GT+KK+AKRNAA ML
Sbjct: 184 GSGTSKKLAKRNAAAKML 201
Score = 50.8 bits (120), Expect = 3e-06
Identities = 55/229 (24%), Positives = 88/229 (38%), Gaps = 64/229 (27%)
Query: 66 AAAESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPL 125
AA TP L ++GK P+Y + G A+ P + +
Sbjct: 3 AANPGKTPISLLQEYGTRIGKTPVYDLL------------KAEGQAHQPNFTF------- 43
Query: 126 LYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPE-RLEVNGRESEEENLNKS 184
++VG G+G +++AAKH AA AL+ L+ + E LE + S ++
Sbjct: 44 ----RVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE 99
Query: 185 EI---------SQVFEIALKRNLPVNFE-------------------------------V 204
+I + V + L R+ P+ + V
Sbjct: 100 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV 159
Query: 205 ARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
+ESGP H K F V F+ G G SKK++K+NAA +L + +P
Sbjct: 160 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVP 208
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/69 (39%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Query: 284 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRN 343
G PIS L Q + K P Y LL G + F +V VG+ + G G +KK AK
Sbjct: 7 GKTPIS-LLQEYGTRIGKTPVYDLLKAEGQAHQPNFTFRVTVGDTSCTGQGPSKKAAKHK 65
Query: 344 AAENMLEIL 352
AAE L+ L
Sbjct: 66 AAEVALKHL 74
>gi|213417919 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 3 [Homo sapiens]
Length = 288
Score = 73.9 bits (180), Expect = 4e-13
Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 183 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 241
K+ I + E +K +N+PV +E R H+ F +V+VG+ GEG SKK++K A
Sbjct: 8 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 66
Query: 242 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 301
A A + LK I + P S + +NPI L ++ +
Sbjct: 67 AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 116
Query: 302 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 349
PEYTL E G +RE+ ++ + G G +KK AKRNAAE L
Sbjct: 117 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 164
Score = 55.5 bits (132), Expect = 1e-07
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 8/138 (5%)
Query: 122 VPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRES 176
VP ++V +VG G+G +++ AKH AA A+ IL+ +P+ L + +
Sbjct: 38 VPTFTFRV--TVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQ 95
Query: 177 EEENLNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKI 236
+ LN Q I LP + +++E GP H + + T + F+ G+G SKK
Sbjct: 96 PKNQLNPIGSLQELAIHHGWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQ 154
Query: 237 SKKNAAIAVLEELKKLPP 254
+K+NAA L + + P
Sbjct: 155 AKRNAAEKFLAKFSNISP 172
Score = 42.7 bits (99), Expect = 0.001
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)
Query: 319 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 372
F +V VG+ T G GT+KK+AK AAE + IL F VP P P + K
Sbjct: 41 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 98
Query: 373 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 425
+ G +++ E E G ++K + + L S + G
Sbjct: 99 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 153
Query: 426 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 485
QA + F+ +P ++T ++ L S K N+ + P
Sbjct: 154 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 212
Query: 486 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 544
T + L +++ QGF + Y D + + N ++ L S+ P + HG G +
Sbjct: 213 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 272
Query: 545 AALNILKLL 553
AA N L+ L
Sbjct: 273 AAHNALQYL 281
>gi|213417911 protein kinase, interferon-inducible double stranded
RNA dependent activator isoform 2 [Homo sapiens]
Length = 302
Score = 73.9 bits (180), Expect = 4e-13
Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 183 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 241
K+ I + E +K +N+PV +E R H+ F +V+VG+ GEG SKK++K A
Sbjct: 22 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 80
Query: 242 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 301
A A + LK I + P S + +NPI L ++ +
Sbjct: 81 AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 130
Query: 302 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 349
PEYTL E G +RE+ ++ + G G +KK AKRNAAE L
Sbjct: 131 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 178
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 84 LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 139
LGK KP + +Q + Y M+ P R VP ++V +VG
Sbjct: 12 LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 67
Query: 140 GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 194
G+G +++ AKH AA A+ IL+ +P+ L + + + LN Q I
Sbjct: 68 GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 127
Query: 195 KRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPP 254
LP + +++E GP H + + T + F+ G+G SKK +K+NAA L + + P
Sbjct: 128 GWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 186
Score = 42.7 bits (99), Expect = 0.001
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)
Query: 319 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 372
F +V VG+ T G GT+KK+AK AAE + IL F VP P P + K
Sbjct: 55 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 112
Query: 373 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 425
+ G +++ E E G ++K + + L S + G
Sbjct: 113 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 167
Query: 426 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 485
QA + F+ +P ++T ++ L S K N+ + P
Sbjct: 168 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 226
Query: 486 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 544
T + L +++ QGF + Y D + + N ++ L S+ P + HG G +
Sbjct: 227 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 286
Query: 545 AALNILKLL 553
AA N L+ L
Sbjct: 287 AAHNALQYL 295
>gi|4505581 protein kinase, interferon-inducible double stranded RNA
dependent activator isoform 1 [Homo sapiens]
Length = 313
Score = 73.9 bits (180), Expect = 4e-13
Identities = 54/168 (32%), Positives = 79/168 (47%), Gaps = 12/168 (7%)
Query: 183 KSEISQVFEIALK-RNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNA 241
K+ I + E +K +N+PV +E R H+ F +V+VG+ GEG SKK++K A
Sbjct: 33 KTPIQVLHEYGMKTKNIPV-YECERSDVQIHVPTFTFRVTVGDITCTGEGTSKKLAKHRA 91
Query: 242 AIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEK 301
A A + LK I + P S + +NPI L ++ +
Sbjct: 92 AEAAINILK----------ANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHHGWR 141
Query: 302 EPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENML 349
PEYTL E G +RE+ ++ + G G +KK AKRNAAE L
Sbjct: 142 LPEYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFL 189
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/180 (27%), Positives = 81/180 (45%), Gaps = 14/180 (7%)
Query: 84 LGKKPMYKPVDPYSRMQSTYNYNMRGGAYP----PRYFYPFPVPPLLYQVELSVGGQQFN 139
LGK KP + +Q + Y M+ P R VP ++V +VG
Sbjct: 23 LGKMITAKPGK--TPIQVLHEYGMKTKNIPVYECERSDVQIHVPTFTFRV--TVGDITCT 78
Query: 140 GKGKTRQAAKHDAAAKALRILQNEP-----LPERLEVNGRESEEENLNKSEISQVFEIAL 194
G+G +++ AKH AA A+ IL+ +P+ L + + + LN Q I
Sbjct: 79 GEGTSKKLAKHRAAEAAINILKANASICFAVPDPLMPDPSKQPKNQLNPIGSLQELAIHH 138
Query: 195 KRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPP 254
LP + +++E GP H + + T + F+ G+G SKK +K+NAA L + + P
Sbjct: 139 GWRLP-EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKFSNISP 197
Score = 42.7 bits (99), Expect = 0.001
Identities = 60/249 (24%), Positives = 97/249 (38%), Gaps = 22/249 (8%)
Query: 319 FVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILG------FKVPQAQPTKPALKSEEKT 372
F +V VG+ T G GT+KK+AK AAE + IL F VP P P + K
Sbjct: 66 FTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVP--DPLMPDPSKQPKN 123
Query: 373 PIKKPGDGRKVTFF------EPGSGDENGTSNKEDEFRMPYL-SHQQLPAGILPMVPEVA 425
+ G +++ E E G ++K + + L S + G
Sbjct: 124 QLNPIGSLQELAIHHGWRLPEYTLSQEGGPAHKREYTTICRLESFMETGKG-----ASKK 178
Query: 426 QAVGVSQGHHTKDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGP 485
QA + F+ +P ++T ++ L S K N+ + P
Sbjct: 179 QAKRNAAEKFLAKFSNISPE-NHISLTNVVGHSLGCTWHSLRNSPGEKINLLKRSLLSIP 237
Query: 486 LTRPSEQLDYLSRVQGFQVEYKDFPKNNKN-EFVSLINCSSQPPLISHGIGKDVESCHDM 544
T + L +++ QGF + Y D + + N ++ L S+ P + HG G +
Sbjct: 238 NTDYIQLLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSD 297
Query: 545 AALNILKLL 553
AA N L+ L
Sbjct: 298 AAHNALQYL 306
>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
sapiens]
Length = 690
Score = 60.5 bits (145), Expect = 4e-09
Identities = 59/232 (25%), Positives = 96/232 (41%), Gaps = 41/232 (17%)
Query: 164 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 212
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 213 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 254
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 255 LPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQAKKEKEPEYTL 307
PAV P ++ + P + E G G NP+ L + K + +Y L
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE-----KRRGLKYEL 543
Query: 308 LTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 359
++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 ISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Score = 52.4 bits (124), Expect = 1e-06
Identities = 76/307 (24%), Positives = 115/307 (37%), Gaps = 73/307 (23%)
Query: 23 KNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSA---LPSASITSTSAAAESITPTVELNA 79
KN++ + + PSTT ++ RP++ PS E P +NA
Sbjct: 348 KNENPVDYTVQIPPSTTYAITPMK--RPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNA 405
Query: 80 LCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFN 139
L M+L + KP Y + T PV ++ + + V G F
Sbjct: 406 L-MRLNQ---LKPGLQYKLVSQTG-----------------PVHAPIFTMSVEVDGNSFE 444
Query: 140 GKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRESEEEN--------------- 180
G +++ AK A K +LQ+ LP E G +S EE
Sbjct: 445 ASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEA 501
Query: 181 -------------------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
L K + V E+ KR + +E+ E+G H K FV +V
Sbjct: 502 VSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR-GLKYELISETGGSHDKRFVMEVE 560
Query: 222 VGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPR----IKKKTKPIVKPQT 277
V +G G +KK++K AA+A LE+L PL K R ++ K KP
Sbjct: 561 VDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPH- 619
Query: 278 SPEYGQG 284
+P +G G
Sbjct: 620 NPGFGMG 626
>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
sapiens]
Length = 702
Score = 60.5 bits (145), Expect = 4e-09
Identities = 59/232 (25%), Positives = 96/232 (41%), Gaps = 41/232 (17%)
Query: 164 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 212
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 213 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 254
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 255 LPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQAKKEKEPEYTL 307
PAV P ++ + P + E G G NP+ L + K + +Y L
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE-----KRRGLKYEL 543
Query: 308 LTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 359
++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 ISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Score = 52.4 bits (124), Expect = 1e-06
Identities = 76/307 (24%), Positives = 115/307 (37%), Gaps = 73/307 (23%)
Query: 23 KNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSA---LPSASITSTSAAAESITPTVELNA 79
KN++ + + PSTT ++ RP++ PS E P +NA
Sbjct: 348 KNENPVDYTVQIPPSTTYAITPMK--RPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNA 405
Query: 80 LCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFN 139
L M+L + KP Y + T PV ++ + + V G F
Sbjct: 406 L-MRLNQ---LKPGLQYKLVSQTG-----------------PVHAPIFTMSVEVDGNSFE 444
Query: 140 GKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRESEEEN--------------- 180
G +++ AK A K +LQ+ LP E G +S EE
Sbjct: 445 ASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEA 501
Query: 181 -------------------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
L K + V E+ KR + +E+ E+G H K FV +V
Sbjct: 502 VSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR-GLKYELISETGGSHDKRFVMEVE 560
Query: 222 VGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPR----IKKKTKPIVKPQT 277
V +G G +KK++K AA+A LE+L PL K R ++ K KP
Sbjct: 561 VDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPH- 619
Query: 278 SPEYGQG 284
+P +G G
Sbjct: 620 NPGFGMG 626
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 60.5 bits (145), Expect = 4e-09
Identities = 59/232 (25%), Positives = 96/232 (41%), Gaps = 41/232 (17%)
Query: 164 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 212
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 213 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 254
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 255 LPAVERVKPRIKKKTKPIVK--PQTSPEYG-----QGINPISRLAQIQQAKKEKEPEYTL 307
PAV P ++ + P + E G G NP+ L + K + +Y L
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAEQGPILTKHGKNPVMELNE-----KRRGLKYEL 543
Query: 308 LTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 359
++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 ISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 595
Score = 52.4 bits (124), Expect = 1e-06
Identities = 76/307 (24%), Positives = 115/307 (37%), Gaps = 73/307 (23%)
Query: 23 KNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSA---LPSASITSTSAAAESITPTVELNA 79
KN++ + + PSTT ++ RP++ PS E P +NA
Sbjct: 348 KNENPVDYTVQIPPSTTYAITPMK--RPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNA 405
Query: 80 LCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFN 139
L M+L + KP Y + T PV ++ + + V G F
Sbjct: 406 L-MRLNQ---LKPGLQYKLVSQTG-----------------PVHAPIFTMSVEVDGNSFE 444
Query: 140 GKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRESEEEN--------------- 180
G +++ AK A K +LQ+ LP E G +S EE
Sbjct: 445 ASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEA 501
Query: 181 -------------------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
L K + V E+ KR + +E+ E+G H K FV +V
Sbjct: 502 VSTPSAAFPSDATAEQGPILTKHGKNPVMELNEKRR-GLKYELISETGGSHDKRFVMEVE 560
Query: 222 VGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPR----IKKKTKPIVKPQT 277
V +G G +KK++K AA+A LE+L PL K R ++ K KP
Sbjct: 561 VDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKPH- 619
Query: 278 SPEYGQG 284
+P +G G
Sbjct: 620 NPGFGMG 626
>gi|212549555 interleukin enhancer binding factor 3 isoform e [Homo
sapiens]
Length = 706
Score = 60.1 bits (144), Expect = 5e-09
Identities = 60/236 (25%), Positives = 96/236 (40%), Gaps = 45/236 (19%)
Query: 164 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 212
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 213 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 254
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 255 LPAVERVKPRIKKKTKPI-----------VKPQTSPEYGQGINPISRLAQIQQAKKEKEP 303
PAV P ++ + P VK Q G NP+ L + K +
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNE-----KRRGL 543
Query: 304 EYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 359
+Y L++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 KYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 599
Score = 50.8 bits (120), Expect = 3e-06
Identities = 76/311 (24%), Positives = 115/311 (36%), Gaps = 77/311 (24%)
Query: 23 KNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSA---LPSASITSTSAAAESITPTVELNA 79
KN++ + + PSTT ++ RP++ PS E P +NA
Sbjct: 348 KNENPVDYTVQIPPSTTYAITPMK--RPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNA 405
Query: 80 LCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFN 139
L M+L + KP Y + T PV ++ + + V G F
Sbjct: 406 L-MRLNQ---LKPGLQYKLVSQTG-----------------PVHAPIFTMSVEVDGNSFE 444
Query: 140 GKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRESEEEN--------------- 180
G +++ AK A K +LQ+ LP E G +S EE
Sbjct: 445 ASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEA 501
Query: 181 -----------------------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFV 217
L K + V E+ KR + +E+ E+G H K FV
Sbjct: 502 VSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR-GLKYELISETGGSHDKRFV 560
Query: 218 TKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPR----IKKKTKPIV 273
+V V +G G +KK++K AA+A LE+L PL K R ++ K
Sbjct: 561 MEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAA 620
Query: 274 KPQTSPEYGQG 284
KP +P +G G
Sbjct: 621 KPH-NPGFGMG 630
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 60.1 bits (144), Expect = 5e-09
Identities = 60/236 (25%), Positives = 96/236 (40%), Gaps = 45/236 (19%)
Query: 164 PLPERLEVNGRESE--------EENLNKSEISQVFEIALKRNL---PVNFEVARESGPPH 212
P+ +E +G E ++ K+E Q ++ N + +++ ++GP H
Sbjct: 369 PMKRPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNALMRLNQLKPGLQYKLVSQTGPVH 428
Query: 213 MKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL------------------KKLPP 254
F V V E G SKK +K + A+ VL+++ ++
Sbjct: 429 APIFTMSVEVDGNSFEASGPSKKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEA 488
Query: 255 LPAVERVKPRIKKKTKPI-----------VKPQTSPEYGQGINPISRLAQIQQAKKEKEP 303
PAV P ++ + P VK Q G NP+ L + K +
Sbjct: 489 KPAVVAPAPVVEAVSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNE-----KRRGL 543
Query: 304 EYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQA 359
+Y L++E G + FVM+V+V +G G+NKKVAK AA LE L P A
Sbjct: 544 KYELISETGGSHDKRFVMEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLA 599
Score = 50.8 bits (120), Expect = 3e-06
Identities = 76/311 (24%), Positives = 115/311 (36%), Gaps = 77/311 (24%)
Query: 23 KNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSA---LPSASITSTSAAAESITPTVELNA 79
KN++ + + PSTT ++ RP++ PS E P +NA
Sbjct: 348 KNENPVDYTVQIPPSTTYAITPMK--RPMEEDGEEKSPSKKKKKIQKKEEKAEPPQAMNA 405
Query: 80 LCMKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFN 139
L M+L + KP Y + T PV ++ + + V G F
Sbjct: 406 L-MRLNQ---LKPGLQYKLVSQTG-----------------PVHAPIFTMSVEVDGNSFE 444
Query: 140 GKGKTRQAAKHDAAAKALRILQNEPLPERLE----VNGRESEEEN--------------- 180
G +++ AK A K +LQ+ LP E G +S EE
Sbjct: 445 ASGPSKKTAKLHVAVK---VLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEA 501
Query: 181 -----------------------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFV 217
L K + V E+ KR + +E+ E+G H K FV
Sbjct: 502 VSTPSAAFPSDATAENVKQQGPILTKHGKNPVMELNEKRR-GLKYELISETGGSHDKRFV 560
Query: 218 TKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPR----IKKKTKPIV 273
+V V +G G +KK++K AA+A LE+L PL K R ++ K
Sbjct: 561 MEVEVDGQKFQGAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAA 620
Query: 274 KPQTSPEYGQG 284
KP +P +G G
Sbjct: 621 KPH-NPGFGMG 630
>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
sapiens]
Length = 674
Score = 59.7 bits (143), Expect = 7e-09
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 180
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
Query: 181 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 235
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
Query: 236 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 295
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
Query: 296 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 355
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Query: 356 VPQAQPTKPALKSE 369
P++ + SE
Sbjct: 300 HLDQTPSRQPIPSE 313
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 287 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 346
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
Query: 347 NML 349
L
Sbjct: 137 KAL 139
Score = 33.5 bits (75), Expect = 0.55
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
sapiens]
Length = 714
Score = 59.7 bits (143), Expect = 7e-09
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 180
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
Query: 181 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 235
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
Query: 236 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 295
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
Query: 296 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 355
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Query: 356 VPQAQPTKPALKSE 369
P++ + SE
Sbjct: 300 HLDQTPSRQPIPSE 313
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 287 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 346
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
Query: 347 NML 349
L
Sbjct: 137 KAL 139
Score = 33.5 bits (75), Expect = 0.55
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
sapiens]
Length = 741
Score = 59.7 bits (143), Expect = 7e-09
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 180
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
Query: 181 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 235
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
Query: 236 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 295
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
Query: 296 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 355
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Query: 356 VPQAQPTKPALKSE 369
P++ + SE
Sbjct: 300 HLDQTPSRQPIPSE 313
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 287 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 346
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
Query: 347 NML 349
L
Sbjct: 137 KAL 139
Score = 33.5 bits (75), Expect = 0.55
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
sapiens]
Length = 701
Score = 59.7 bits (143), Expect = 7e-09
Identities = 71/254 (27%), Positives = 102/254 (40%), Gaps = 48/254 (18%)
Query: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEEN 180
PV L+ + + V GQ F G G T++ AK AA KALR P
Sbjct: 103 PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP---------------- 146
Query: 181 LNKSEISQVFEIALKRNLPVNFEVARESG--PPHMKN-FVT--KVSVGEFVGEGEGKSKK 235
N SE +A+ R L VN + + P + N F T K +VG S
Sbjct: 147 -NASEA----HLAMGRTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFS 201
Query: 236 ISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQ 295
S + A P+PA + + P++ P P G NP+ L +++
Sbjct: 202 SSGDLSLSA--------SPVPA------SLAQPPLPVLPPFPPP---SGKNPVMILNELR 244
Query: 296 QAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFK 355
K Y L+E G + FVM V V EG+G NKK+AK AA++ L +
Sbjct: 245 PGLK-----YDFLSESGESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAIFNL 299
Query: 356 VPQAQPTKPALKSE 369
P++ + SE
Sbjct: 300 HLDQTPSRQPIPSE 313
Score = 40.0 bits (92), Expect = 0.006
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 2/63 (3%)
Query: 287 PISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAE 346
P + L Q+ + K + YTLL++ G FVM V+V EG+G KK AK +AAE
Sbjct: 79 PKNALMQLNEIKPGLQ--YTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAE 136
Query: 347 NML 349
L
Sbjct: 137 KAL 139
Score = 33.5 bits (75), Expect = 0.55
Identities = 18/54 (33%), Positives = 27/54 (50%)
Query: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
+ + + ++GP H FV V V V EG G +KK +K +AA L + P
Sbjct: 93 LQYTLLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFP 146
>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
sapiens]
Length = 931
Score = 56.2 bits (134), Expect = 8e-08
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 183 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 241
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 207 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 266
Query: 242 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 293
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 267 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 326
Query: 294 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 352
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 327 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 385
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 127 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 179
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 240 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 299
Query: 180 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 223
KS ++ + E K F + + GP H F V+VG
Sbjct: 300 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 359
Query: 224 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 267
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 360 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 419
Query: 268 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 327
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 420 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 471
Query: 328 HTAEGT-GTNKKVAKRNAAENMLEIL 352
+KK K+ AA+ L +L
Sbjct: 472 RWFPAVCAHSKKQGKQEAADAALRVL 497
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/209 (25%), Positives = 86/209 (41%), Gaps = 40/209 (19%)
Query: 68 AESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPP 124
AES TPT +A GK P+ ++ ++ ++ + + G A+ P++ Y
Sbjct: 302 AESQTPTP--SATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC----- 354
Query: 125 LLYQVELSVGGQQFNG-KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVN 172
++VG Q F +++ AK AA +A++ L E PE + ++
Sbjct: 355 ------VAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLD 408
Query: 173 GRESEEEN-----------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
ES N LN + + + E A F++ +SGPPH FV +
Sbjct: 409 NLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 468
Query: 222 V-GEFVGEGEGKSKKISKKNAAIAVLEEL 249
V G + SKK K+ AA A L L
Sbjct: 469 VGGRWFPAVCAHSKKQGKQEAADAALRVL 497
>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
sapiens]
Length = 1181
Score = 56.2 bits (134), Expect = 8e-08
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 183 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 241
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 242 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 293
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 294 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 352
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/190 (26%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 68 AESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPP 124
AES TPT +A GK P+ ++ ++ ++ + + G A+ P++ Y
Sbjct: 597 AESQTPTP--SATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC----- 649
Query: 125 LLYQVELSVGGQQFNG-KGKTRQAAKHDAAAKALRILQNEPLPERLEVNGRESEEE---N 180
++VG Q F +++ AK AA +A++ L E N E
Sbjct: 650 ------VAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQVRKIGELVRY 703
Query: 181 LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKK 239
LN + + + E A F++ +SGPPH FV + V G + SKK K+
Sbjct: 704 LNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQ 763
Query: 240 NAAIAVLEEL 249
AA A L L
Sbjct: 764 EAADAALRVL 773
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/250 (23%), Positives = 98/250 (39%), Gaps = 35/250 (14%)
Query: 127 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 179
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 180 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 223
KS ++ + E K F + + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 224 EFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQ 283
+ SKK++K+ AA E +K L +K +V+ +
Sbjct: 655 QTFPSVSAPSKKVAKQMAAE---EAMKALHGEATNSMASDNQVRKIGELVRYLNT----- 706
Query: 284 GINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGT-GTNKKVAKR 342
NP+ L + ++ E+ L+ + G P +FV Q KVG +KK K+
Sbjct: 707 --NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQ 763
Query: 343 NAAENMLEIL 352
AA+ L +L
Sbjct: 764 EAADAALRVL 773
>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
sapiens]
Length = 1200
Score = 56.2 bits (134), Expect = 8e-08
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 183 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 241
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 242 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 293
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 294 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 352
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 127 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 179
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 180 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 223
KS ++ + E K F + + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 224 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 267
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
Query: 268 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 327
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
Query: 328 HTAEGT-GTNKKVAKRNAAENMLEIL 352
+KK K+ AA+ L +L
Sbjct: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/209 (25%), Positives = 86/209 (41%), Gaps = 40/209 (19%)
Query: 68 AESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPP 124
AES TPT +A GK P+ ++ ++ ++ + + G A+ P++ Y
Sbjct: 597 AESQTPTP--SATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC----- 649
Query: 125 LLYQVELSVGGQQFNG-KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVN 172
++VG Q F +++ AK AA +A++ L E PE + ++
Sbjct: 650 ------VAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLD 703
Query: 173 GRESEEEN-----------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
ES N LN + + + E A F++ +SGPPH FV +
Sbjct: 704 NLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 763
Query: 222 V-GEFVGEGEGKSKKISKKNAAIAVLEEL 249
V G + SKK K+ AA A L L
Sbjct: 764 VGGRWFPAVCAHSKKQGKQEAADAALRVL 792
>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
sapiens]
Length = 1226
Score = 56.2 bits (134), Expect = 8e-08
Identities = 51/180 (28%), Positives = 85/180 (47%), Gaps = 11/180 (6%)
Query: 183 KSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNA 241
K+ IS + E A + F + +SGPPH F +V + G E SKK++K++A
Sbjct: 502 KNPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDA 561
Query: 242 AI----AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQT----SPEYGQGINPISRLAQ 293
A+ +LEE K + E +K+++ + QT + + G +P++ L +
Sbjct: 562 AMKAMTILLEEAKAKDSGKSEESSHYSTEKESEKTAESQTPTPSATSFFSGKSPVTTLLE 621
Query: 294 IQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEG-TGTNKKVAKRNAAENMLEIL 352
K E+ LL++ G +F V VG T + +KKVAK+ AAE ++ L
Sbjct: 622 CMH-KLGNSCEFRLLSKEGPAHEPKFQYCVAVGAQTFPSVSAPSKKVAKQMAAEEAMKAL 680
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 48/266 (18%)
Query: 127 YQVELSVGGQQFN-GKGKTRQAAKHDAAAKALRILQNEPLP------ERLEVNGRESEEE 179
++ ++ + G++F + +++ AK DAA KA+ IL E E E E E
Sbjct: 535 FKFQVVINGREFPPAEAGSKKVAKQDAAMKAMTILLEEAKAKDSGKSEESSHYSTEKESE 594
Query: 180 NL---------------NKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVSVG- 223
KS ++ + E K F + + GP H F V+VG
Sbjct: 595 KTAESQTPTPSATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYCVAVGA 654
Query: 224 EFVGEGEGKSKKISKKNAAIAVLEELKK----------------LPPLPAVERVKPRIKK 267
+ SKK++K+ AA ++ L L +E + P +
Sbjct: 655 QTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLDNLESMMPNKVR 714
Query: 268 KTKPIVKPQTSPEYGQGINPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 327
K +V+ + NP+ L + ++ E+ L+ + G P +FV Q KVG
Sbjct: 715 KIGELVRYLNT-------NPVGGLLEYARSHGFAA-EFKLVDQSGPPHEPKFVYQAKVGG 766
Query: 328 HTAEGT-GTNKKVAKRNAAENMLEIL 352
+KK K+ AA+ L +L
Sbjct: 767 RWFPAVCAHSKKQGKQEAADAALRVL 792
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/209 (25%), Positives = 86/209 (41%), Gaps = 40/209 (19%)
Query: 68 AESITPTVELNALCMKLGKKPMYKPVDPYSRMQSTYNYNM---RGGAYPPRYFYPFPVPP 124
AES TPT +A GK P+ ++ ++ ++ + + G A+ P++ Y
Sbjct: 597 AESQTPTP--SATSFFSGKSPVTTLLECMHKLGNSCEFRLLSKEGPAHEPKFQYC----- 649
Query: 125 LLYQVELSVGGQQFNG-KGKTRQAAKHDAAAKALRILQNEPL--------PERL---EVN 172
++VG Q F +++ AK AA +A++ L E PE + ++
Sbjct: 650 ------VAVGAQTFPSVSAPSKKVAKQMAAEEAMKALHGEATNSMASDNQPEGMISESLD 703
Query: 173 GRESEEEN-----------LNKSEISQVFEIALKRNLPVNFEVARESGPPHMKNFVTKVS 221
ES N LN + + + E A F++ +SGPPH FV +
Sbjct: 704 NLESMMPNKVRKIGELVRYLNTNPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAK 763
Query: 222 V-GEFVGEGEGKSKKISKKNAAIAVLEEL 249
V G + SKK K+ AA A L L
Sbjct: 764 VGGRWFPAVCAHSKKQGKQEAADAALRVL 792
>gi|21361745 spermatid perinuclear RNA binding protein [Homo
sapiens]
Length = 672
Score = 55.8 bits (133), Expect = 1e-07
Identities = 50/187 (26%), Positives = 78/187 (41%), Gaps = 27/187 (14%)
Query: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL-------KKL 252
+ +++ +SGP H F V V E G SKK +K + A+ VL+ + +
Sbjct: 402 LQYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADI 461
Query: 253 PPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGINPISRLAQIQQA--------------- 297
+ + E+ K +T V +S G S +++
Sbjct: 462 ECMSSDEKSDNESKNET---VSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMEL 518
Query: 298 -KKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKV 356
+K + +Y L++E G + FVM+V+V G G NKKVAK +AA LE L F
Sbjct: 519 NEKRRGLKYELISETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKL-FSG 577
Query: 357 PQAQPTK 363
P A K
Sbjct: 578 PNAANNK 584
Score = 47.4 bits (111), Expect = 4e-05
Identities = 47/193 (24%), Positives = 77/193 (39%), Gaps = 38/193 (19%)
Query: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRIL-------------------- 160
PV ++ + + V G + G +++ AK A K L+ +
Sbjct: 412 PVHAPVFTMSVDVDGTTYEASGPSKKTAKLHVAVKVLQAMGYPTGFDADIECMSSDEKSD 471
Query: 161 ---QNEPLPERLEVNGRESEEENLNKSEI------------SQVFEIALKRNLPVNFEVA 205
+NE + N S E + E+ + V E+ KR + +E+
Sbjct: 472 NESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVMELNEKRR-GLKYELI 530
Query: 206 RESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLPPLPAVERVKPRI 265
E+G H K FV +V V G G +KK++K +AA+A LE+L P A K +I
Sbjct: 531 SETGGSHDKRFVMEVEVDGQKFRGAGPNKKVAKASAALAALEKLFSGP--NAANNKKKKI 588
Query: 266 KKKTKPIVKPQTS 278
+ K +V S
Sbjct: 589 IPQAKGVVNTAVS 601
Score = 37.7 bits (86), Expect = 0.029
Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 5/70 (7%)
Query: 285 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 344
+N + RL QI+ +Y LL++ G F M V V T E +G +KK AK +
Sbjct: 389 MNALMRLNQIRPGL-----QYKLLSQSGPVHAPVFTMSVDVDGTTYEASGPSKKTAKLHV 443
Query: 345 AENMLEILGF 354
A +L+ +G+
Sbjct: 444 AVKVLQAMGY 453
Score = 31.6 bits (70), Expect = 2.1
Identities = 29/123 (23%), Positives = 52/123 (42%), Gaps = 15/123 (12%)
Query: 45 ENAGRPIQNSALPSASITSTSAAAESITPTVELNA---LCMKLGKKPMYKPVDPYSRMQS 101
E + +N + S S +T + + T+E+ + GK P+ + ++ R
Sbjct: 468 EKSDNESKNETVSSNSSNNTGNSTTETSSTLEVRTQGPILTASGKNPVME-LNEKRRGLK 526
Query: 102 TYNYNMRGGAYPPRYFYPFPVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALRILQ 161
+ GG++ R+ +E+ V GQ+F G G ++ AK AA AL L
Sbjct: 527 YELISETGGSHDKRFV-----------MEVEVDGQKFRGAGPNKKVAKASAALAALEKLF 575
Query: 162 NEP 164
+ P
Sbjct: 576 SGP 578
>gi|208431829 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform b [Homo sapiens]
Length = 510
Score = 46.2 bits (108), Expect = 8e-05
Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 195 KRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
K+ + + ++ SGPPH + F +V + G EGEG+SKK +K AA +E L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 254 PLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEPEYTLLT 309
KK P++ T+ G I I+R+AQ KK Y
Sbjct: 78 -----------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCA 122
Query: 310 ERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 346
G+ F + K+G + GTG+ K+ AK+ AA+
Sbjct: 123 S-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159
Score = 33.9 bits (76), Expect = 0.42
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 304 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 361
+Y L G P R F QV + G EG G +KK AK AA+ +EIL + P
Sbjct: 26 KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84
>gi|208431827 eukaryotic translation initiation factor 2-alpha
kinase 2 isoform a [Homo sapiens]
Length = 551
Score = 46.2 bits (108), Expect = 8e-05
Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 195 KRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
K+ + + ++ SGPPH + F +V + G EGEG+SKK +K AA +E L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 254 PLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEPEYTLLT 309
KK P++ T+ G I I+R+AQ KK Y
Sbjct: 78 -----------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCA 122
Query: 310 ERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 346
G+ F + K+G + GTG+ K+ AK+ AA+
Sbjct: 123 S-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159
Score = 33.9 bits (76), Expect = 0.42
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 304 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 361
+Y L G P R F QV + G EG G +KK AK AA+ +EIL + P
Sbjct: 26 KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84
>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
2 isoform a [Homo sapiens]
Length = 551
Score = 46.2 bits (108), Expect = 8e-05
Identities = 47/158 (29%), Positives = 71/158 (44%), Gaps = 24/158 (15%)
Query: 195 KRNLPVNFEVARESGPPHMKNFVTKVSV-GEFVGEGEGKSKKISKKNAAIAVLEELKKLP 253
K+ + + ++ SGPPH + F +V + G EGEG+SKK +K AA +E L K
Sbjct: 20 KQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNK-- 77
Query: 254 PLPAVERVKPRIKKKTKPIVKPQTSP----EYGQGINPISRLAQIQQAKKEKEPEYTLLT 309
KK P++ T+ G I I+R+AQ KK Y
Sbjct: 78 -----------EKKAVSPLLLTTTNSSEGLSMGNYIGLINRIAQ----KKRLTVNYEQCA 122
Query: 310 ERGLPRRREFVMQVKVG-NHTAEGTGTNKKVAKRNAAE 346
G+ F + K+G + GTG+ K+ AK+ AA+
Sbjct: 123 S-GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLAAK 159
Score = 33.9 bits (76), Expect = 0.42
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 1/59 (1%)
Query: 304 EYTLLTERGLPRRREFVMQVKV-GNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQP 361
+Y L G P R F QV + G EG G +KK AK AA+ +EIL + P
Sbjct: 26 KYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVEILNKEKKAVSP 84
>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
Length = 739
Score = 43.5 bits (101), Expect = 5e-04
Identities = 49/215 (22%), Positives = 75/215 (34%), Gaps = 58/215 (26%)
Query: 200 VNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEELKKLP------ 253
+ + ++GP H F V V EG G +KK +K AA L + P
Sbjct: 140 LQYRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALRSFVQFPNACQAH 199
Query: 254 --------------------------------PLPAVERVKP-------------RIKKK 268
P P + +P R+ +
Sbjct: 200 LAMGGGPGPGTDFTSDQADFPDTLFQEFEPPAPRPGLAGGRPGDAALLSAAYGRRRLLCR 259
Query: 269 TKPIVKPQTSPEYGQGI-NPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGN 327
+V P + G NP+ L +++ + Y L E R R FVM V V
Sbjct: 260 ALDLVGPTPATPAAPGERNPVVLLNRLRAGLR-----YVCLAEPAERRARSFVMAVSVDG 314
Query: 328 HTAEGTGTNKKVAKRNAAENML-EILGFKVPQAQP 361
T EG+G +KK+A+ AA+ L E+ ++P P
Sbjct: 315 RTFEGSGRSKKLARGQAAQAALQELFDIQMPGHAP 349
Score = 32.3 bits (72), Expect = 1.2
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 285 INPISRLAQIQQAKKEKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNA 344
+ P + L Q+ + + + Y +++ G F + V+V T EGTG KK AK A
Sbjct: 124 VAPKNALVQLHELRPGLQ--YRTVSQTGPVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRA 181
Query: 345 AE 346
AE
Sbjct: 182 AE 183
Score = 29.6 bits (65), Expect = 7.9
Identities = 16/38 (42%), Positives = 21/38 (55%)
Query: 121 PVPPLLYQVELSVGGQQFNGKGKTRQAAKHDAAAKALR 158
PV ++ V + V G F G G T++ AK AA ALR
Sbjct: 150 PVHAPVFAVAVEVNGLTFEGTGPTKKKAKMRAAELALR 187
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,114,059
Number of Sequences: 37866
Number of extensions: 1185216
Number of successful extensions: 3466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 3206
Number of HSP's gapped (non-prelim): 250
length of query: 577
length of database: 18,247,518
effective HSP length: 108
effective length of query: 469
effective length of database: 14,157,990
effective search space: 6640097310
effective search space used: 6640097310
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.