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Search of human proteins with 80978934
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
(804 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens] 1606 0.0
gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens] 1582 0.0
gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens] 1175 0.0
gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens] 853 0.0
gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activat... 853 0.0
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens] 817 0.0
gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH do... 815 0.0
gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH do... 810 0.0
gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH do... 809 0.0
gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens] 807 0.0
gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH do... 806 0.0
gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 792 0.0
gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repea... 791 0.0
gi|110227617 centaurin, gamma 3 isoform b [Homo sapiens] 533 e-151
gi|239755300 PREDICTED: similar to centaurin, gamma-like family,... 313 3e-85
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 143 6e-34
gi|206725422 G protein-coupled receptor kinase interacting ArfGA... 131 3e-30
gi|206725420 G protein-coupled receptor kinase interacting ArfGA... 131 3e-30
gi|21237786 G protein-coupled receptor kinase interacting ArfGAP... 131 3e-30
gi|17149830 G protein-coupled receptor kinase interacting ArfGAP... 131 3e-30
gi|17149832 G protein-coupled receptor kinase interacting ArfGAP... 131 3e-30
gi|206725415 G protein-coupled receptor kinase interacting ArfGA... 131 3e-30
gi|46094081 development and differentiation enhancing factor 1 [... 129 8e-30
gi|7661880 centaurin beta1 [Homo sapiens] 129 8e-30
gi|187608516 centaurin, beta 2 [Homo sapiens] 129 1e-29
gi|146231998 G protein-coupled receptor kinase interactor 1 isof... 126 9e-29
gi|41393573 G protein-coupled receptor kinase interactor 1 isofo... 126 9e-29
gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 118 2e-26
gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain... 118 2e-26
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 115 2e-25
>gi|80978934 centaurin, gamma 2 isoform 2 [Homo sapiens]
Length = 804
Score = 1606 bits (4159), Expect = 0.0
Identities = 804/804 (100%), Positives = 804/804 (100%)
Query: 1 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS 60
MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
Sbjct: 1 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS 60
Query: 61 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL 120
QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL
Sbjct: 61 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL 120
Query: 121 LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD 180
LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD
Sbjct: 121 LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD 180
Query: 181 AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI 240
AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI
Sbjct: 181 AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI 240
Query: 241 GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT 300
GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT
Sbjct: 241 GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT 300
Query: 301 ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS 360
ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS
Sbjct: 301 ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS 360
Query: 361 LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI 420
LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI
Sbjct: 361 LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI 420
Query: 421 SSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKK 480
SSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKK
Sbjct: 421 SSPKTNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKK 480
Query: 481 STSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQS 540
STSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQS
Sbjct: 481 STSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQS 540
Query: 541 CESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRN 600
CESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRN
Sbjct: 541 CESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRN 600
Query: 601 LGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIR 660
LGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIR
Sbjct: 601 LGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIR 660
Query: 661 AKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTAL 720
AKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTAL
Sbjct: 661 AKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTAL 720
Query: 721 HLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVL 780
HLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVL
Sbjct: 721 HLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVL 780
Query: 781 MATPNLSRRNNNRNNSSGRVPTII 804
MATPNLSRRNNNRNNSSGRVPTII
Sbjct: 781 MATPNLSRRNNNRNNSSGRVPTII 804
>gi|80978930 centaurin, gamma 2 isoform 1 [Homo sapiens]
Length = 857
Score = 1582 bits (4095), Expect = 0.0
Identities = 804/857 (93%), Positives = 804/857 (93%), Gaps = 53/857 (6%)
Query: 1 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS 60
MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS
Sbjct: 1 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS 60
Query: 61 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL 120
QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL
Sbjct: 61 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL 120
Query: 121 LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD 180
LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD
Sbjct: 121 LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQD 180
Query: 181 AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI 240
AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI
Sbjct: 181 AISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSI 240
Query: 241 GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT 300
GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT
Sbjct: 241 GPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPT 300
Query: 301 ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS 360
ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS
Sbjct: 301 ANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKS 360
Query: 361 LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI 420
LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI
Sbjct: 361 LNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPI 420
Query: 421 SSPKTNGLSKDMSSLHISPN---------------------------------------- 440
SSPKTNGLSKDMSSLHISPN
Sbjct: 421 SSPKTNGLSKDMSSLHISPNSGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQ 480
Query: 441 -------------SDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKA 487
SDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKA
Sbjct: 481 WSEATVIANSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKA 540
Query: 488 DGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNK 547
DGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNK
Sbjct: 541 DGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNK 600
Query: 548 SRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSR 607
SRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSR
Sbjct: 601 SRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSR 660
Query: 608 VRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKL 667
VRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKL
Sbjct: 661 VRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKL 720
Query: 668 FLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKG 727
FLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKG
Sbjct: 721 FLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKG 780
Query: 728 NVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLS 787
NVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLS
Sbjct: 781 NVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLS 840
Query: 788 RRNNNRNNSSGRVPTII 804
RRNNNRNNSSGRVPTII
Sbjct: 841 RRNNNRNNSSGRVPTII 857
>gi|110227613 centaurin, gamma 3 isoform a [Homo sapiens]
Length = 911
Score = 1175 bits (3039), Expect = 0.0
Identities = 590/852 (69%), Positives = 691/852 (81%), Gaps = 51/852 (5%)
Query: 4 QQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEW 63
Q L+NSAAIRAEIQRFESVHPNIY+IY+L+ER+E+ LQNQIREHVI+IED+FVNSQEW
Sbjct: 60 QFALSNSAAIRAEIQRFESVHPNIYAIYDLIERIEDLALQNQIREHVISIEDSFVNSQEW 119
Query: 64 TLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIR 123
TLSRSVPELKVGIVGNL+SGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIR
Sbjct: 120 TLSRSVPELKVGIVGNLSSGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIR 179
Query: 124 DEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAIS 183
DEGGPPE QFA WVDAV+FVFSLEDEISFQTVY+Y+ R+ ++RN SE+P+VLVGTQDAIS
Sbjct: 180 DEGGPPELQFAAWVDAVVFVFSLEDEISFQTVYNYFLRLCSFRNASEVPMVLVGTQDAIS 239
Query: 184 SANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPC 243
+ANPRVIDD+RARKLS DLKRCTYYETCATYGLNVERVFQDVAQK+VA RKKQQL+IGPC
Sbjct: 240 AANPRVIDDSRARKLSTDLKRCTYYETCATYGLNVERVFQDVAQKVVALRKKQQLAIGPC 299
Query: 244 KSLPNSPSHSSVCSAQVSAVHISQTSNGGGS-LSDYSSSVPSTPSTSQKELRIDVPPTAN 302
KSLPNSPSHS+V +A + AVHI+Q +NGGGS SDYSSSVPSTPS SQ+ELRI+ ++
Sbjct: 300 KSLPNSPSHSAVSAASIPAVHINQATNGGGSAFSDYSSSVPSTPSISQRELRIETIAASS 359
Query: 303 TPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLN 362
TPTP+RKQSKRRSN+FTSRKG+D D+EKK E + DSIGSGRAIPIKQG+LLKRSGKSLN
Sbjct: 360 TPTPIRKQSKRRSNIFTSRKGADLDREKKAAECKVDSIGSGRAIPIKQGILLKRSGKSLN 419
Query: 363 KEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISS 422
KEWKKKYVTLCDNG+LTYHPSLHDYMQN+HGKEIDLLRTTVKVPGKR PRAT A AP +S
Sbjct: 420 KEWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRLPRATPATAPGTS 479
Query: 423 PKTNGLSKDMSSLHI-------------SPNSDTGLGDSVCSSP----------SISS-- 457
P+ NGLS + S+ + S +S+ L S + P S+SS
Sbjct: 480 PRANGLSVERSNTQLGGGTGAPHSASSASLHSERPLSSSAWAGPRPEGLHQRSCSVSSAD 539
Query: 458 ------------------------TTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGT 493
++SPKLDPPPSPH+NRKKHRRKKST + DG S
Sbjct: 540 QWSEATTSLPPGMQHPASGPAEVLSSSPKLDPPPSPHSNRKKHRRKKSTGTPRPDGPSSA 599
Query: 494 AEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQ 553
EE EE+FEF++VSLTGQTWHFEA+T EER+ WVQ++++QILASLQ C S+K+K+RL +Q
Sbjct: 600 TEEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQ 659
Query: 554 SEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDL 613
+ A+A+Q++R +RGNS C+DC+ NP+WASLNLGALMCIECSGIHR+LG HLSRVRSLDL
Sbjct: 660 NAALAVQAVRTVRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDL 719
Query: 614 DDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLP 673
DDWP EL+ VM+++GN LANSVWE + G +KP D+ REEKERWIRAKYEQKLFLAPLP
Sbjct: 720 DDWPPELLAVMTAMGNALANSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLFLAPLP 779
Query: 674 CTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQ 733
+++ LGQ LLRA ++DLR ++LLAHGS++EVNET G+GDGRTALHL+ NVV Q
Sbjct: 780 SSDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQ 839
Query: 734 LLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRRN-NN 792
LLIWYGVDV +RDA G T LAYAR+A SQEC D+L+Q+GCP E L TPN N N
Sbjct: 840 LLIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGEGCGLAPTPNREPANGTN 899
Query: 793 RNNSSGRVPTII 804
+ R P+++
Sbjct: 900 PSAELHRSPSLL 911
>gi|7661962 centaurin, gamma 1 isoform PIKE-S [Homo sapiens]
Length = 836
Score = 853 bits (2204), Expect = 0.0
Identities = 458/820 (55%), Positives = 581/820 (70%), Gaps = 51/820 (6%)
Query: 1 MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNS 60
M+ Q+Q AA+RAE++R E + + +L ERV++P LQ+ I+ + +I +A +NS
Sbjct: 1 MHAQRQFV-VAAVRAEVRRHEVAKQALNRLRKLAERVDDPELQDSIQASLDSIREAVINS 59
Query: 61 QEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLL 120
QEWTLSRS+PEL++G++G+ SGKS+L+HR+LTG+Y E E ++KKE++VDGQ++L+
Sbjct: 60 QEWTLSRSIPELRLGVLGDARSGKSSLIHRFLTGSYQVLEKTESEQYKKEMLVDGQTHLV 119
Query: 121 LIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSE--IPLVLVGT 178
LIR+E G P+A+F+ W DAVIFVFSLEDE SFQ V + ++++ R + L LVGT
Sbjct: 120 LIREEAGAPDAKFSGWADAVIFVFSLEDENSFQAVSRLHGQLSSLRGEGRGGLALALVGT 179
Query: 179 QDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQL 238
QD IS+++PRV+ DARAR L D+KRC+YYETCATYGLNV+RVFQ+VAQK+V RK+QQL
Sbjct: 180 QDRISASSPRVVGDARARALCADMKRCSYYETCATYGLNVDRVFQEVAQKVVTLRKQQQL 239
Query: 239 SIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVP 298
+ CKSLP+SPSHS+ S Q SNGG + SDYSSS+PS+P+ +ELR +
Sbjct: 240 -LAACKSLPSSPSHSAA-----STPVAGQASNGGHT-SDYSSSLPSSPNVGHRELRAEAA 292
Query: 299 PTANTPTP--VRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKR 356
A TP + + +KRR++LF +R+GSD EK+ L+SR ++ GSGRAIPIKQ LLKR
Sbjct: 293 AVAGLSTPGSLHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQSFLLKR 350
Query: 357 SGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSA 416
SG SLNKEWKKKYVTL NG L YHPS++DY+ + HGKE+DLLRTTVKVPGKRPPRA SA
Sbjct: 351 SGNSLNKEWKKKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPPRAISA 410
Query: 417 CAPISSPKTNGLSKDMSSLHI---------------SPNS---------------DTGLG 446
P +S NGL KDMS++ + SP+S D L
Sbjct: 411 FGPSAS--INGLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKPDRNLA 468
Query: 447 DSVCSSPSISSTTSP-KLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFII 505
++ + + S SP +PPPSP KK RRKK T+ K +G +G AEE ENFEF+I
Sbjct: 469 RALSTDCTPSGDLSPLSREPPPSPMV--KKQRRKKLTTPSKTEGSAGQAEE--ENFEFLI 524
Query: 506 VSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNM 565
VS TGQTWHFEA ++EERDAWVQAIESQILASLQ CESSK K R SQSEA+A+Q+IRN
Sbjct: 525 VSSTGQTWHFEAASFEERDAWVQAIESQILASLQCCESSKVKLRTDSQSEAVAIQAIRNA 584
Query: 566 RGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMS 625
+GNS CVDC NP WASLNLGAL+CIECSGIHRNLGTHLSRVRSLDLDDWP EL V++
Sbjct: 585 KGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDDWPRELTLVLT 644
Query: 626 SIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLR 685
+IGN+ AN VWE ++GR KPS DS+REE+E WIRAKYEQ LFLAPL +E LG+ L
Sbjct: 645 AIGNDTANRVWESDTRGRAKPSRDSSREERESWIRAKYEQLLFLAPLSTSEEPLGRQLWA 704
Query: 686 ATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTAR 745
A +D+ T +LLLAH ++ + + R+ LHLA +VV+ QLL+WYG DV AR
Sbjct: 705 AVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHLAAELAHVVITQLLLWYGADVAAR 764
Query: 746 DAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPN 785
DA G TAL YARQA SQ C D+LLQ+GCP E TP+
Sbjct: 765 DAQGRTALFYARQAGSQLCADILLQHGCPGEGGSAATTPS 804
>gi|148806877 ankyrin repeat and GTPase domain Arf GTPase activating
protein 11 [Homo sapiens]
Length = 550
Score = 853 bits (2204), Expect = 0.0
Identities = 425/516 (82%), Positives = 467/516 (90%), Gaps = 3/516 (0%)
Query: 261 SAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTS 320
S VHI++ NGGGSL++YSSS+P TPSTSQ++L VPPTANTPTP+ KQS SNLFTS
Sbjct: 36 STVHITKKRNGGGSLNNYSSSIPLTPSTSQEDLYFSVPPTANTPTPICKQSMGWSNLFTS 95
Query: 321 RKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTY 380
KGSDPDK +K LES AD+IGSGRAIPIKQGMLLKRSGK L K WKKKYVTLC NGVLTY
Sbjct: 96 EKGSDPDKGRKALESHADTIGSGRAIPIKQGMLLKRSGKWL-KTWKKKYVTLCSNGVLTY 154
Query: 381 HPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPN 440
+ SL DYM+N+H KEIDL +T+KVPGK P ATSACAPISS K+NGLSKDM +LH+S N
Sbjct: 155 YSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSKSNGLSKDMEALHMSAN 214
Query: 441 SDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEEN 500
SD GLGDS+C SPSISSTTSPKL+ PPSPHAN+KKH +KKST+N K DGLS TAEE+EE
Sbjct: 215 SDIGLGDSICFSPSISSTTSPKLNLPPSPHANKKKHLKKKSTNNLKDDGLSSTAEEEEE- 273
Query: 501 FEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQ 560
+F+IVS+TGQT HF+ATTYEERDAWVQAI+SQILASLQSCESSK+KS+LTSQSEAMALQ
Sbjct: 274 -KFMIVSVTGQTCHFKATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSEAMALQ 332
Query: 561 SIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVEL 620
SI+NMRGNSHCVDCETQNP WASLNLG LMCIECSGIHR+LGT LSRVRSL+LDDWPVEL
Sbjct: 333 SIQNMRGNSHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVEL 392
Query: 621 IKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLG 680
KVMSSIGN+LANS+WE SSQG+TKPS++STREEKERWIR+KYE KLFLAPLPCTELSLG
Sbjct: 393 RKVMSSIGNDLANSIWEGSSQGQTKPSIESTREEKERWIRSKYEHKLFLAPLPCTELSLG 452
Query: 681 QHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGV 740
QHLLRATADEDLRTAILLLAHGSR+EVNETCGEGDG TALHLACRKGNVVLAQLLIWYGV
Sbjct: 453 QHLLRATADEDLRTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGV 512
Query: 741 DVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
DV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 513 DVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 548
>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
Length = 1192
Score = 817 bits (2111), Expect = 0.0
Identities = 439/783 (56%), Positives = 548/783 (69%), Gaps = 66/783 (8%)
Query: 56 AFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDG 115
A +NSQEWTLSRS+PEL++G++G+ SGKS+L+HR+LTG+Y E E ++KKE++VDG
Sbjct: 391 AVINSQEWTLSRSIPELRLGVLGDARSGKSSLIHRFLTGSYQVLEKTESEQYKKEMLVDG 450
Query: 116 QSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSE--IPL 173
Q++L+LIR+E G P+A+F+ W DAVIFVFSLEDE SFQ V + ++++ R + L
Sbjct: 451 QTHLVLIREEAGAPDAKFSGWADAVIFVFSLEDENSFQAVSRLHGQLSSLRGEGRGGLAL 510
Query: 174 VLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATR 233
LVGTQD IS+++PRV+ DARAR L D+KRC+YYETCATYGLNV+RVFQ+VAQK+V R
Sbjct: 511 ALVGTQDRISASSPRVVGDARARALCADMKRCSYYETCATYGLNVDRVFQEVAQKVVTLR 570
Query: 234 KKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKEL 293
K+QQL + CKSLP+SPSHS+ S Q SNGG + SDYSSS+PS+P+ +EL
Sbjct: 571 KQQQL-LAACKSLPSSPSHSAA-----STPVAGQASNGGHT-SDYSSSLPSSPNVGHREL 623
Query: 294 RIDVPPTANTPTP--VRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQG 351
R + A TP + + +KRR++LF +R+GSD EK+ L+SR ++ GSGRAIPIKQ
Sbjct: 624 RAEAAAVAGLSTPGSLHRAAKRRTSLFANRRGSD--SEKRSLDSRGETTGSGRAIPIKQS 681
Query: 352 MLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPP 411
LLKRSG SLNKEWKKKYVTL NG L YHPS++DY+ + HGKE+DLLRTTVKVPGKRPP
Sbjct: 682 FLLKRSGNSLNKEWKKKYVTLSSNGFLLYHPSINDYIHSTHGKEMDLLRTTVKVPGKRPP 741
Query: 412 RATSACAPISSPKTNGLSKDMSSLHI---------------SPNS--------------- 441
RA SA P +S NGL KDMS++ + SP+S
Sbjct: 742 RAISAFGPSAS--INGLVKDMSTVQMGEGLEATTPMPSPSPSPSSLQPPPDQTSKHLLKP 799
Query: 442 DTGLGDSVCSSPSISSTTSP-KLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQ--- 497
D L ++ + + S SP +PPPSP KK RRKK T+ K +G +G AE +
Sbjct: 800 DRNLARALSTDCTPSGDLSPLSREPPPSPMV--KKQRRKKLTTPSKTEGSAGQAEAKRKM 857
Query: 498 ---------------EENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCE 542
EENFEF+IVS TGQTWHFEA ++EERDAWVQAIESQILASLQ CE
Sbjct: 858 WKLKSFGSLRNIYKAEENFEFLIVSSTGQTWHFEAASFEERDAWVQAIESQILASLQCCE 917
Query: 543 SSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLG 602
SSK K R SQSEA+A+Q+IRN +GNS CVDC NP WASLNLGAL+CIECSGIHRNLG
Sbjct: 918 SSKVKLRTDSQSEAVAIQAIRNAKGNSICVDCGAPNPTWASLNLGALICIECSGIHRNLG 977
Query: 603 THLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAK 662
THLSRVRSLDLDDWP EL V+++IGN+ AN VWE ++GR KPS DS+REE+E WIRAK
Sbjct: 978 THLSRVRSLDLDDWPRELTLVLTAIGNDTANRVWESDTRGRAKPSRDSSREERESWIRAK 1037
Query: 663 YEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHL 722
YEQ LFLAPL +E LG+ L A +D+ T +LLLAH ++ + + R+ LHL
Sbjct: 1038 YEQLLFLAPLSTSEEPLGRQLWAAVQAQDVATVLLLLAHARHGPLDTSVEDPQLRSPLHL 1097
Query: 723 ACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMA 782
A +VV+ QLL+WYG DV ARDA G TAL YARQA SQ C D+LLQ+GCP E
Sbjct: 1098 AAELAHVVITQLLLWYGADVAARDAQGRTALFYARQAGSQLCADILLQHGCPGEGGSAAT 1157
Query: 783 TPN 785
TP+
Sbjct: 1158 TPS 1160
>gi|221136914 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 5 [Homo sapiens]
Length = 686
Score = 815 bits (2106), Expect = 0.0
Identities = 415/532 (78%), Positives = 456/532 (85%), Gaps = 32/532 (6%)
Query: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
S+P+ HS VS VHI++ NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP
Sbjct: 185 SIPDEQLHSFA----VSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240
Query: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
TPV K+S R SNLFTS KGS PDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSHPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299
Query: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSACAPISS K
Sbjct: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359
Query: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484
+NGLSKDM DTGLGDS+C SPSISSTTSPKL+PPPSPHAN+KKH +KKST+N
Sbjct: 360 SNGLSKDM---------DTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNN 410
Query: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544
F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESS
Sbjct: 411 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESS 452
Query: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604
K+KS+LTSQSEAMALQSI+NMRGN+HCVD ETQNP WASLNLG LMCIECSGIHR+LGT
Sbjct: 453 KSKSQLTSQSEAMALQSIQNMRGNAHCVDYETQNPKWASLNLGVLMCIECSGIHRSLGTR 512
Query: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664
LSRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQG+TKPSV STREEKERWIR+KYE
Sbjct: 513 LSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSVKSTREEKERWIRSKYE 572
Query: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724
+KLFLAPLPCTELSLGQHLLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 573 EKLFLAPLPCTELSLGQHLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 632
Query: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
RKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 633 RKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 684
>gi|156104893 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 4 [Homo sapiens]
Length = 663
Score = 810 bits (2092), Expect = 0.0
Identities = 411/532 (77%), Positives = 454/532 (85%), Gaps = 32/532 (6%)
Query: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
S+P+ HS VS VHI + NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP
Sbjct: 162 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
Query: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
TPV K+S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 276
Query: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSAC PIS+ K
Sbjct: 277 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISTSK 336
Query: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484
+NGLSKDM DTGLGDS+C SPSISSTTSPKL+PPPSPHAN+KKH +KKST+N
Sbjct: 337 SNGLSKDM---------DTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNN 387
Query: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544
F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESS
Sbjct: 388 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESS 429
Query: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604
K+KS+LTSQS+AMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+LGT
Sbjct: 430 KSKSQLTSQSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTR 489
Query: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664
LSRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQG+TKPS STREEKERWIR+KYE
Sbjct: 490 LSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYE 549
Query: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724
+KLFLAPLPCTELSLGQ LLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 550 EKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 609
Query: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
RKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPD+
Sbjct: 610 RKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDK 661
>gi|117956371 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 8 [Homo sapiens]
Length = 663
Score = 809 bits (2090), Expect = 0.0
Identities = 412/532 (77%), Positives = 452/532 (84%), Gaps = 32/532 (6%)
Query: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
S+P+ HS VS VHI + NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP
Sbjct: 162 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
Query: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
TPV K+S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 276
Query: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSAC PISS K
Sbjct: 277 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSK 336
Query: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484
+NGLSKDM DTGLGDS+C SPSISSTTSPKL+PPPSPHAN+KKH +KKST+N
Sbjct: 337 SNGLSKDM---------DTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNN 387
Query: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544
F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESS
Sbjct: 388 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESS 429
Query: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604
K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIH +LGT
Sbjct: 430 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHHSLGTR 489
Query: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664
LSRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQG+TKPS STREEKERWIR+KYE
Sbjct: 490 LSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYE 549
Query: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724
+KLFLAPLPCTELSLGQ LL ATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 550 EKLFLAPLPCTELSLGQQLLWATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 609
Query: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
RKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 610 RKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661
>gi|166851846 centaurin, gamma-like family, member 3 [Homo sapiens]
Length = 686
Score = 807 bits (2085), Expect = 0.0
Identities = 411/532 (77%), Positives = 452/532 (84%), Gaps = 32/532 (6%)
Query: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
S+P+ HS VS VHI + NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP
Sbjct: 185 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 240
Query: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
TPV K+S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299
Query: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
WKKKYVTLC NG+LTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSAC PISS K
Sbjct: 300 WKKKYVTLCSNGMLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISSSK 359
Query: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484
+NGLSKDM DTGLGDS+C SPSISSTTSPKL+PPPSPHAN+KKH +KKST+N
Sbjct: 360 SNGLSKDM---------DTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNN 410
Query: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544
F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESS
Sbjct: 411 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESS 452
Query: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604
K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+LG H
Sbjct: 453 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGPH 512
Query: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664
LSRVRSL+LDDWPVEL KVMSSI N+LANS+WE SSQG+TKPS STREEKERWIR+KYE
Sbjct: 513 LSRVRSLELDDWPVELRKVMSSIVNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYE 572
Query: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724
+KLFLAPLPCTELSLGQ LLRATADEDL+TAILLLAHGS +EVNETCGEGDG TALHLAC
Sbjct: 573 EKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSCEEVNETCGEGDGCTALHLAC 632
Query: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
RKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 633 RKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 684
>gi|117956373 ArfGAP with GTPase domain, ankyrin repeat and PH
domain 7 [Homo sapiens]
Length = 663
Score = 806 bits (2082), Expect = 0.0
Identities = 410/532 (77%), Positives = 452/532 (84%), Gaps = 32/532 (6%)
Query: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
S+P+ HS VS VHI++ NGGGSL++YSSS+PSTPSTSQ++ + VPPTANTP
Sbjct: 162 SIPDEQLHSFA----VSTVHITKNRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTP 217
Query: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
TPV K+S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 218 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 276
Query: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
WKKKYVTLC NGVLTY+ SL DYM+ +H KEIDL +T+KVPGK P AT AC PISS K
Sbjct: 277 WKKKYVTLCSNGVLTYYSSLGDYMKYIHKKEIDLQTSTIKVPGKWPSLATLACTPISSSK 336
Query: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484
++GLSKDM DTGLGDS+C SPSISSTT PKL+PPPSPHAN+KKH +KKST+N
Sbjct: 337 SDGLSKDM---------DTGLGDSICFSPSISSTTIPKLNPPPSPHANKKKHLKKKSTNN 387
Query: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544
F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSCESS
Sbjct: 388 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESS 429
Query: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604
K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+LGT
Sbjct: 430 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTR 489
Query: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664
LSRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQGRTKP+ STREEKERWIR+KYE
Sbjct: 490 LSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGRTKPTEKSTREEKERWIRSKYE 549
Query: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724
+KLFLAPLPCTELSLGQ LLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 550 EKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 609
Query: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
RKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 610 RKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 661
>gi|239744074 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 9 [Homo sapiens]
Length = 684
Score = 792 bits (2045), Expect = 0.0
Identities = 406/532 (76%), Positives = 447/532 (84%), Gaps = 34/532 (6%)
Query: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
S+P+ HS VS VHI + NGGGSL++YSSS+P TPSTSQ++ + VPPTANTP
Sbjct: 185 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
Query: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
TPV K+S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 241 TPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299
Query: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSACAPISS K
Sbjct: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359
Query: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484
+NGLSKDM DTGLGDS+C SP ISSTTSPKL+PPPSPHAN+KKH +KKST+N
Sbjct: 360 SNGLSKDM---------DTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNN 410
Query: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544
F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSC+SS
Sbjct: 411 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSS 452
Query: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604
K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+ GT
Sbjct: 453 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTR 512
Query: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664
LSRVRSL+LDDWPVEL KVMSSIGNELANS+WE SSQG+TKPS+ STREEKE WIR+KYE
Sbjct: 513 LSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYE 572
Query: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724
+KLFLAPLPCTELSLGQ LLRAT DEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 573 EKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 632
Query: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
RKGNVVL QLL GVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 633 RKGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 682
>gi|239744064 PREDICTED: ArfGAP with GTPase domain, ankyrin repeat
and PH domain 10 [Homo sapiens]
Length = 684
Score = 791 bits (2042), Expect = 0.0
Identities = 406/532 (76%), Positives = 446/532 (83%), Gaps = 34/532 (6%)
Query: 245 SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTP 304
S+P+ HS VS VHI + NGGGSL++YSSS+P TPSTSQ++ + VPPTANTP
Sbjct: 185 SIPDEQLHSFA----VSTVHIMKKRNGGGSLNNYSSSIPPTPSTSQEDPQFSVPPTANTP 240
Query: 305 TPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKE 364
TPV K S R SNLFTS KGSDPDKE+K E+ AD+IGSGRAIPIKQGMLLKRSGK L K
Sbjct: 241 TPVCKLSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWL-KT 299
Query: 365 WKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK 424
WKKKYVTLC NGVLTY+ SL DYM+N+H KEIDL +T+KVPGK P ATSACAPISS K
Sbjct: 300 WKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLRTSTIKVPGKWPSLATSACAPISSSK 359
Query: 425 TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSN 484
+NGLSKDM DTGLGDS+C SP ISSTTSPKL+PPPSPHAN+KKH +KKST+N
Sbjct: 360 SNGLSKDM---------DTGLGDSICFSPGISSTTSPKLNPPPSPHANKKKHLKKKSTNN 410
Query: 485 FKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESS 544
F +IVS TGQTWHFEATTYEERDAWVQAI+SQILASLQSC+SS
Sbjct: 411 F------------------MIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCKSS 452
Query: 545 KNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH 604
K+KS+LTSQSEAMALQSI+NMRGN+HCVDCETQNP WASLNLG LMCIECSGIHR+ GT
Sbjct: 453 KSKSQLTSQSEAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSFGTR 512
Query: 605 LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYE 664
LSRVRSL+LDDWPVEL KVMSSIGNELANS+WE SSQG+TKPS+ STREEKE WIR+KYE
Sbjct: 513 LSRVRSLELDDWPVELRKVMSSIGNELANSIWEGSSQGQTKPSIKSTREEKEWWIRSKYE 572
Query: 665 QKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLAC 724
+KLFLAPLPCTELSLGQ LLRAT DEDL+TAILLLAHGSR+EVNETCGEGDG TALHLAC
Sbjct: 573 EKLFLAPLPCTELSLGQQLLRATTDEDLQTAILLLAHGSREEVNETCGEGDGCTALHLAC 632
Query: 725 RKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
RKGNVVL QLL GVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 633 RKGNVVLEQLL--XGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 682
>gi|110227617 centaurin, gamma 3 isoform b [Homo sapiens]
Length = 396
Score = 533 bits (1374), Expect = e-151
Identities = 263/317 (82%), Positives = 295/317 (93%), Gaps = 1/317 (0%)
Query: 4 QQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQNQIREHVIAIEDAFVNSQEW 63
Q L+NSAAIRAEIQRFESVHPNIY+IY+L+ER+E+ LQNQIREHVI+IED+FVNSQEW
Sbjct: 60 QFALSNSAAIRAEIQRFESVHPNIYAIYDLIERIEDLALQNQIREHVISIEDSFVNSQEW 119
Query: 64 TLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIR 123
TLSRSVPELKVGIVGNL+SGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIR
Sbjct: 120 TLSRSVPELKVGIVGNLSSGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIR 179
Query: 124 DEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAIS 183
DEGGPPE QFA WVDAV+FVFSLEDEISFQTVY+Y+ R+ ++RN SE+P+VLVGTQDAIS
Sbjct: 180 DEGGPPELQFAAWVDAVVFVFSLEDEISFQTVYNYFLRLCSFRNASEVPMVLVGTQDAIS 239
Query: 184 SANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPC 243
+ANPRVIDD+RARKLS DLKRCTYYETCATYGLNVERVFQDVAQK+VA RKKQQL+IGPC
Sbjct: 240 AANPRVIDDSRARKLSTDLKRCTYYETCATYGLNVERVFQDVAQKVVALRKKQQLAIGPC 299
Query: 244 KSLPNSPSHSSVCSAQVSAVHISQTSNGGGS-LSDYSSSVPSTPSTSQKELRIDVPPTAN 302
KSLPNSPSHS+V +A + AVHI+Q +NGGGS SDYSSSVPSTPS SQ+ELRI+ ++
Sbjct: 300 KSLPNSPSHSAVSAASIPAVHINQATNGGGSAFSDYSSSVPSTPSISQRELRIETIAASS 359
Query: 303 TPTPVRKQSKRRSNLFT 319
TPTP+RKQSKRRSN+FT
Sbjct: 360 TPTPIRKQSKRRSNIFT 376
>gi|239755300 PREDICTED: similar to centaurin, gamma-like family,
member 1 [Homo sapiens]
Length = 284
Score = 313 bits (803), Expect = 3e-85
Identities = 154/176 (87%), Positives = 165/176 (93%)
Query: 601 LGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIR 660
L + SRVRSL+LDDWPVEL KVMSSIGN+LANS+WE SSQG+TKPS STREEKERWIR
Sbjct: 107 LHSFASRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIR 166
Query: 661 AKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTAL 720
+KYE+KLFLAPLPCT+LSLGQ LLRATADEDL+TAILLLAHGSR+EVNETCGEGDG TAL
Sbjct: 167 SKYEEKLFLAPLPCTDLSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTAL 226
Query: 721 HLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDE 776
HLACRKGNVVLAQLLIWYGVDV ARDAHGNTAL YARQASSQECI+VLLQYGCPDE
Sbjct: 227 HLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDE 282
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 143 bits (361), Expect = 6e-34
Identities = 79/200 (39%), Positives = 118/200 (59%), Gaps = 22/200 (11%)
Query: 495 EEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQ----SCES------- 543
E+ E F F ++S T ++ +A + + R AWVQA+++ I ++ + SC S
Sbjct: 324 EDIERRFCFEVLSPT-KSCMLQADSEKLRQAWVQAVQASIASAYRESPDSCYSERLDRTA 382
Query: 544 SKNKSRLTSQSEAM--------ALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECS 595
S + S + S ++ LQ ++++ GNS C DC +P WAS+NLG L+CIECS
Sbjct: 383 SPSTSSIDSATDTRERGVKGESVLQRVQSVAGNSQCGDCGQPDPRWASINLGVLLCIECS 442
Query: 596 GIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQ--GRTKPSVDSTRE 653
GIHR+LG H S+VRSL LD W EL+K+M +GN N ++E + G KP+ S+R+
Sbjct: 443 GIHRSLGVHCSKVRSLTLDSWEPELLKLMCELGNSAVNQIYEAQCEGAGSRKPTASSSRQ 502
Query: 654 EKERWIRAKYEQKLFLAPLP 673
+KE WI+ KY +K FL P
Sbjct: 503 DKEAWIKDKYVEKKFLRKAP 522
Score = 44.3 bits (103), Expect = 5e-04
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 676 ELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLL 735
EL G RA DL LAHG+ EVN E +G+T L A G++++ + L
Sbjct: 665 ELHPGLLAHRAARARDLPALAAALAHGA--EVNWADAEDEGKTPLVQAVLGGSLIVCEFL 722
Query: 736 IWYGVDVTARDAHGNTALAYA 756
+ G DV RD+ G L +A
Sbjct: 723 LQNGADVNQRDSRGRAPLHHA 743
>gi|206725422 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 5 [Homo sapiens]
Length = 729
Score = 131 bits (329), Expect = 3e-30
Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 17/222 (7%)
Query: 563 RNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIK 622
+ +R + C DC +P+WAS+N G +C EC +HR+LG H+S+VR L WP L++
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 623 VMSSIGNELANSVWEES-------SQGRTKPS-VDSTREEKERWIRAKYEQKLFLAPLPC 674
++ ++ N ANS+WE S GR K + D K +IRAKY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 675 ------TELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGN 728
T L + L + +L T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 729 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
++ A+LL YG D +D+ G T + YARQ E + L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|206725420 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 6 [Homo sapiens]
Length = 681
Score = 131 bits (329), Expect = 3e-30
Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 17/222 (7%)
Query: 563 RNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIK 622
+ +R + C DC +P+WAS+N G +C EC +HR+LG H+S+VR L WP L++
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 623 VMSSIGNELANSVWEES-------SQGRTKPS-VDSTREEKERWIRAKYEQKLFLAPLPC 674
++ ++ N ANS+WE S GR K + D K +IRAKY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 675 ------TELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGN 728
T L + L + +L T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 729 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
++ A+LL YG D +D+ G T + YARQ E + L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|21237786 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 3 [Homo sapiens]
Length = 679
Score = 131 bits (329), Expect = 3e-30
Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 17/222 (7%)
Query: 563 RNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIK 622
+ +R + C DC +P+WAS+N G +C EC +HR+LG H+S+VR L WP L++
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 623 VMSSIGNELANSVWEES-------SQGRTKPS-VDSTREEKERWIRAKYEQKLFLAPLPC 674
++ ++ N ANS+WE S GR K + D K +IRAKY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 675 ------TELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGN 728
T L + L + +L T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 729 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
++ A+LL YG D +D+ G T + YARQ E + L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|17149830 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 1 [Homo sapiens]
Length = 759
Score = 131 bits (329), Expect = 3e-30
Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 17/222 (7%)
Query: 563 RNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIK 622
+ +R + C DC +P+WAS+N G +C EC +HR+LG H+S+VR L WP L++
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 623 VMSSIGNELANSVWEES-------SQGRTKPS-VDSTREEKERWIRAKYEQKLFLAPLPC 674
++ ++ N ANS+WE S GR K + D K +IRAKY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 675 ------TELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGN 728
T L + L + +L T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 729 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
++ A+LL YG D +D+ G T + YARQ E + L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|17149832 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 2 [Homo sapiens]
Length = 631
Score = 131 bits (329), Expect = 3e-30
Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 17/222 (7%)
Query: 563 RNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIK 622
+ +R + C DC +P+WAS+N G +C EC +HR+LG H+S+VR L WP L++
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 623 VMSSIGNELANSVWEES-------SQGRTKPS-VDSTREEKERWIRAKYEQKLFLAPLPC 674
++ ++ N ANS+WE S GR K + D K +IRAKY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 675 ------TELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGN 728
T L + L + +L T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 729 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
++ A+LL YG D +D+ G T + YARQ E + L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|206725415 G protein-coupled receptor kinase interacting ArfGAP 2
isoform 4 [Homo sapiens]
Length = 471
Score = 131 bits (329), Expect = 3e-30
Identities = 75/222 (33%), Positives = 115/222 (51%), Gaps = 17/222 (7%)
Query: 563 RNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIK 622
+ +R + C DC +P+WAS+N G +C EC +HR+LG H+S+VR L WP L++
Sbjct: 3 KRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQ 62
Query: 623 VMSSIGNELANSVWEES-------SQGRTKPS-VDSTREEKERWIRAKYEQKLFLAPLPC 674
++ ++ N ANS+WE S GR K + D K +IRAKY+ F+ LPC
Sbjct: 63 MVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPC 122
Query: 675 ------TELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGN 728
T L + L + +L T + LL+ G++ G T LH+A + G
Sbjct: 123 RDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGNTPLHVASKAGQ 179
Query: 729 VVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
++ A+LL YG D +D+ G T + YARQ E + L++
Sbjct: 180 ILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVE 221
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 129 bits (325), Expect = 8e-30
Identities = 88/283 (31%), Positives = 141/283 (49%), Gaps = 14/283 (4%)
Query: 498 EENFEFIIVSLTGQTWHFEATTYEERDAWVQAI---ESQILASLQSCESSKNKSRLTSQS 554
E+ F ++S +T+HF+A ++ AW+ + + + L E S ++ L +
Sbjct: 380 EDKKSFDLIS-HNRTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQSAGENSLEDLT 438
Query: 555 EAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD 614
+A+ ++ ++ + GN C DC + P W S NLG L CIECSGIHR +G H+SR++SL+LD
Sbjct: 439 KAI-IEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELD 497
Query: 615 DWPVELIKVMSSIGNELANSVWEESSQGRT-KPSVDSTREEKERWIRAKYEQKLFLAPLP 673
+ + ++GN N + E + + KP+ S ++ +I AKY F
Sbjct: 498 KLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAKYVDHRFSRKTC 557
Query: 674 CTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETC---GEGDGRTALHLACR---KG 727
T + LL A DL I + A G E+ E G+ G TALHLA R +
Sbjct: 558 STSSAKLNELLEAIKSRDLLALIQVYAEGV--ELMEPLLEPGQELGETALHLAVRTADQT 615
Query: 728 NVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
++ L L+ ++ + A GNT L Y S EC+ +LL+
Sbjct: 616 SLHLVDFLVQNCGNLDKQTALGNTVLHYCSMYSKPECLKLLLR 658
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 129 bits (325), Expect = 8e-30
Identities = 97/329 (29%), Positives = 140/329 (42%), Gaps = 71/329 (21%)
Query: 496 EQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNK-------- 547
+ E F F +VS T ++ +A + WV A++S I ++ +
Sbjct: 322 DSERRFCFEVVS-TSKSCLLQADSERLLQLWVSAVQSSIASAFSQARLDDSPRGPGQGSG 380
Query: 548 -----SRLTSQSEAMA-----------LQSIRNMRGNSHCVDCETQNPNWASLNLGALMC 591
S T S MA + ++++ GN+ C DC P WAS+NLG +C
Sbjct: 381 HLAIGSAATLGSGGMARGREPGGVGHVVAQVQSVDGNAQCCDCREPAPEWASINLGVTLC 440
Query: 592 IECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRT--KPSVD 649
I+CSGIHR+LG H S+VRSL LD W EL+K+M +GN + N ++E + KP
Sbjct: 441 IQCSGIHRSLGVHFSKVRSLTLDSWEPELVKLMCELGNVIINQIYEARVEAMAVKKPGPS 500
Query: 650 STREEKERWIRAKYEQKLFLAPLP------------------------------------ 673
+R+EKE WI AKY +K FL LP
Sbjct: 501 CSRQEKEAWIHAKYVEKKFLTKLPEIRGRRGGRGRPRGQPPVPPKPSIRPRPGSLRSKPE 560
Query: 674 -----CTELSLGQHLLRATA-DEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKG 727
L G L RA+ L T LAHG+ +VN G D T L A
Sbjct: 561 PPSEDLGSLHPGALLFRASGHPPSLPTMADALAHGA--DVNWVNGGQDNATPLIQATAAN 618
Query: 728 NVVLAQLLIWYGVDVTARDAHGNTALAYA 756
+++ + L+ G +V D+ G L +A
Sbjct: 619 SLLACEFLLQNGANVNQADSAGRGPLHHA 647
Score = 39.7 bits (91), Expect = 0.011
Identities = 28/86 (32%), Positives = 44/86 (51%), Gaps = 4/86 (4%)
Query: 683 LLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDV 742
L++ATA L LL +G+ VN+ + GR LH A G+ LA L + G D+
Sbjct: 611 LIQATAANSLLACEFLLQNGAN--VNQA--DSAGRGPLHHATILGHTGLACLFLKRGADL 666
Query: 743 TARDAHGNTALAYARQASSQECIDVL 768
ARD+ G L A + ++ + + +L
Sbjct: 667 GARDSEGRDPLTIAMETANADIVTLL 692
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 129 bits (324), Expect = 1e-29
Identities = 75/194 (38%), Positives = 114/194 (58%), Gaps = 21/194 (10%)
Query: 495 EEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSC---------ESSK 545
E+ E F F +VS T ++ +A + + R AW++A+++ I + + +SS
Sbjct: 322 EDIERRFCFEVVSPT-KSCMLQADSEKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSP 380
Query: 546 NKSRLTSQSEAM--------ALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGI 597
+ L S +E+ ALQ ++ + GN+ C DC +P WAS+NLG +CIECSGI
Sbjct: 381 STGSLDSGNESKEKLLKGESALQRVQCIPGNASCCDCGLADPRWASINLGITLCIECSGI 440
Query: 598 HRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEES--SQGRTKPSVDSTREEK 655
HR+LG H S+VRSL LD W EL+K+M +GN++ N V+E + G KP R+EK
Sbjct: 441 HRSLGVHFSKVRSLTLDTWEPELLKLMCELGNDVINRVYEANVEKMGIKKPQ-PGQRQEK 499
Query: 656 ERWIRAKYEQKLFL 669
E +IRAKY ++ F+
Sbjct: 500 EAYIRAKYVERKFV 513
Score = 36.6 bits (83), Expect = 0.095
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Query: 672 LPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVL 731
L L+ G L RA+ +++L LAHG+ +VN E + T L A G++V
Sbjct: 599 LDSKHLNPGLQLYRASYEKNLPKMAEALAHGA--DVNWANSEENKATPLIQAVLGGSLVT 656
Query: 732 AQLLIWYGVDVTARDAHGNTALAYA 756
+ L+ G +V RD G L +A
Sbjct: 657 CEFLLQNGANVNQRDVQGRGPLHHA 681
>gi|146231998 G protein-coupled receptor kinase interactor 1 isoform
1 [Homo sapiens]
Length = 770
Score = 126 bits (316), Expect = 9e-29
Identities = 73/214 (34%), Positives = 111/214 (51%), Gaps = 17/214 (7%)
Query: 571 CVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNE 630
C DC +P WAS++ G L+C EC +HR+LG H+S V+ L WP L++++ ++ +
Sbjct: 11 CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70
Query: 631 LANSVWEES-------SQGRTKPS-VDSTREEKERWIRAKYEQKLFLAPLPC------TE 676
ANS+WE S GR K + D K +IRAKY+ F+ LPC T
Sbjct: 71 GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130
Query: 677 LSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLI 736
L + L + +L T + LL+ G++ G T LH+A + G + A+LL+
Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187
Query: 737 WYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
YG D + D +G T + YARQA E + L++
Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221
>gi|41393573 G protein-coupled receptor kinase interactor 1 isoform
2 [Homo sapiens]
Length = 761
Score = 126 bits (316), Expect = 9e-29
Identities = 73/214 (34%), Positives = 111/214 (51%), Gaps = 17/214 (7%)
Query: 571 CVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNE 630
C DC +P WAS++ G L+C EC +HR+LG H+S V+ L WP L++++ ++ +
Sbjct: 11 CADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASN 70
Query: 631 LANSVWEES-------SQGRTKPS-VDSTREEKERWIRAKYEQKLFLAPLPC------TE 676
ANS+WE S GR K + D K +IRAKY+ F+ LPC T
Sbjct: 71 GANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTA 130
Query: 677 LSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLI 736
L + L + +L T + LL+ G++ G T LH+A + G + A+LL+
Sbjct: 131 KDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH---PEKGTTPLHVAAKAGQTLQAELLV 187
Query: 737 WYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
YG D + D +G T + YARQA E + L++
Sbjct: 188 VYGADPGSPDVNGRTPIDYARQAGHHELAERLVE 221
>gi|221307473 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform b [Homo sapiens]
Length = 894
Score = 118 bits (295), Expect = 2e-26
Identities = 88/279 (31%), Positives = 132/279 (47%), Gaps = 24/279 (8%)
Query: 511 QTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEA-----------MAL 559
+T+HF+A E +AWV +++ +L S + + S A + +
Sbjct: 361 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 420
Query: 560 QSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD-DWPV 618
+++ GNS C DC +P W S NLG L CI+CSG+HR LG SR++SL LD P
Sbjct: 421 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 480
Query: 619 ELIKVMSSIGNELANSVWEES--SQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTE 676
EL+ + ++GN N V E S G KPS +S + +I AKY + F CT
Sbjct: 481 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 537
Query: 677 LSLGQHLLRATADEDLRTAILLLAHGS--RDEVNETCGEGDGRTALHLACRKGN---VVL 731
Q L A + DL + + A+G + + LHLA + N + L
Sbjct: 538 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 595
Query: 732 AQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
+I G + A+ A GNTAL YA + +C+ +LL+
Sbjct: 596 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 634
>gi|19923540 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
isoform a [Homo sapiens]
Length = 903
Score = 118 bits (295), Expect = 2e-26
Identities = 88/279 (31%), Positives = 132/279 (47%), Gaps = 24/279 (8%)
Query: 511 QTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEA-----------MAL 559
+T+HF+A E +AWV +++ +L S + + S A + +
Sbjct: 370 RTYHFQAEDEHECEAWVSVLQNSKDEALSSAFLGEPSAGPGSWGSAGHDGEPHDLTKLLI 429
Query: 560 QSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLD-DWPV 618
+++ GNS C DC +P W S NLG L CI+CSG+HR LG SR++SL LD P
Sbjct: 430 AEVKSRPGNSQCCDCGAADPTWLSTNLGVLTCIQCSGVHRELGVRFSRMQSLTLDLLGPS 489
Query: 619 ELIKVMSSIGNELANSVWEES--SQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTE 676
EL+ + ++GN N V E S G KPS +S + +I AKY + F CT
Sbjct: 490 ELLLAL-NMGNTSFNEVMEAQLPSHGGPKPSAESDMGTRRDYIMAKYVEHRFAR--RCTP 546
Query: 677 LSLGQHLLRATADEDLRTAILLLAHGS--RDEVNETCGEGDGRTALHLACRKGN---VVL 731
Q L A + DL + + A+G + + LHLA + N + L
Sbjct: 547 EP--QRLWTAICNRDLLSVLEAFANGQDFGQPLPGPDAQAPEELVLHLAVKVANQASLPL 604
Query: 732 AQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
+I G + A+ A GNTAL YA + +C+ +LL+
Sbjct: 605 VDFIIQNGGHLDAKAADGNTALHYAALYNQPDCLKLLLK 643
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 115 bits (287), Expect = 2e-25
Identities = 77/288 (26%), Positives = 135/288 (46%), Gaps = 13/288 (4%)
Query: 493 TAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSC---ESSKNKSR 549
T E+++ F+ I +T+HF+A +E W+ +++ +L + + + ++
Sbjct: 358 TNPEEKKCFDLISHD---RTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENN 414
Query: 550 LTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVR 609
+ + + ++ M GN C DC +P W S NLG L CIECSGIHR LG H SR++
Sbjct: 415 IVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNLGILTCIECSGIHRELGVHYSRMQ 474
Query: 610 SLDLDDWPVELIKVMSSIGNELANSVWE--ESSQGRTKPSVDSTREEKERWIRAKYEQKL 667
SL LD + + +IGN N + E ++ KP+ S ++ +I AKY ++
Sbjct: 475 SLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERR 534
Query: 668 FLAPLPCTELSLGQHLLRATADEDLRTAILLLAHG--SRDEVNETCGEGDGRTALHLACR 725
+ + L A D+ + A G +++ G TALHLA R
Sbjct: 535 YARKKHADNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVR 594
Query: 726 ---KGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQ 770
+ ++ + L+ ++ + G+TAL Y + EC+ +LL+
Sbjct: 595 SVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLTDNAECLKLLLR 642
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,852,432
Number of Sequences: 37866
Number of extensions: 1504964
Number of successful extensions: 7105
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 358
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 5289
Number of HSP's gapped (non-prelim): 1728
length of query: 804
length of database: 18,247,518
effective HSP length: 110
effective length of query: 694
effective length of database: 14,082,258
effective search space: 9773087052
effective search space used: 9773087052
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.