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Search of human proteins with 7705971
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7705971 leucine zipper protein 4 [Homo sapiens]
(313 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7705971 leucine zipper protein 4 [Homo sapiens] 640 0.0
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 62 9e-10
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 60 3e-09
gi|40068059 CBF1 interacting corepressor [Homo sapiens] 59 4e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 58 9e-09
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 58 9e-09
gi|60097902 filaggrin [Homo sapiens] 58 1e-08
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 2e-08
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 56 4e-08
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 56 4e-08
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 55 6e-08
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 55 8e-08
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 55 8e-08
gi|62122917 filaggrin family member 2 [Homo sapiens] 54 2e-07
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 53 3e-07
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 53 3e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 52 7e-07
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 52 7e-07
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 52 7e-07
gi|50962882 G patch domain containing 8 [Homo sapiens] 52 9e-07
gi|9945320 cyclin L1 [Homo sapiens] 51 2e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 50 2e-06
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 50 2e-06
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 50 2e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 50 3e-06
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 3e-06
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 3e-06
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 3e-06
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 3e-06
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 50 3e-06
>gi|7705971 leucine zipper protein 4 [Homo sapiens]
Length = 313
Score = 640 bits (1651), Expect = 0.0
Identities = 313/313 (100%), Positives = 313/313 (100%)
Query: 1 MASFRKLTLSEKVPPNHPSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESP 60
MASFRKLTLSEKVPPNHPSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESP
Sbjct: 1 MASFRKLTLSEKVPPNHPSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESP 60
Query: 61 SRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDN 120
SRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDN
Sbjct: 61 SRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDN 120
Query: 121 YEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQL 180
YEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQL
Sbjct: 121 YEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQL 180
Query: 181 KRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVD 240
KRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVD
Sbjct: 181 KRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVD 240
Query: 241 TQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSER 300
TQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSER
Sbjct: 241 TQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSER 300
Query: 301 HQRYSTGKNTITT 313
HQRYSTGKNTITT
Sbjct: 301 HQRYSTGKNTITT 313
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 61.6 bits (148), Expect = 9e-10
Identities = 50/191 (26%), Positives = 79/191 (41%), Gaps = 15/191 (7%)
Query: 46 EEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHP 105
+ ++ + + SPS+ ++HR RR + RS SE +H S + H
Sbjct: 1699 QRSHRGPSERRHHSPSK---RSHRSPARRSH---RSPSERSHHSPSERSHHSPSERRHHS 1752
Query: 106 LNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNH 165
+ E+ CS + + ++ + + +P SE+S P E H S
Sbjct: 1753 PS-----ERSHCSPSERSHCSPSERRHRSPSERRHHSP--SEKSHHSPSERSHHSPSERR 1805
Query: 166 LERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQ-SERSHGHSERSH-GHSERSHGHSE 223
L +S S + P RSH ++RSH + SERSH SE+SH ERS
Sbjct: 1806 RHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPS 1865
Query: 224 RSHGHSKRSRS 234
GHS ++
Sbjct: 1866 ERRGHSSSGKT 1876
Score = 57.4 bits (137), Expect = 2e-08
Identities = 56/213 (26%), Positives = 82/213 (38%), Gaps = 36/213 (16%)
Query: 49 NKRQNHSKKESPSRQQS-KAHR----HRHRRGYSRCRSNSEEGNH-------DKKPSQKP 96
++R++HS E R S ++HR RHR R E +H + PSQ+
Sbjct: 1642 SQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRS 1701
Query: 97 SGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEG---NPDKSEESQGQP 153
S + + + ++ + +E++ H S + SE S P
Sbjct: 1702 HRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSP 1761
Query: 154 -----------------EENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKR 196
E HHS ++H S +S S + +RH P H +R
Sbjct: 1762 SERSHCSPSERRHRSPSERRHHSPSEKSHHSPS-ERSHHSPSERRRHSPLERSRHSLLER 1820
Query: 197 SH--GQSERSHGHSERSHGH-SERSHGHSERSH 226
SH RSH ERSH SERSH SE+SH
Sbjct: 1821 SHRSPSERRSHRSFERSHRRISERSHSPSEKSH 1853
Score = 55.1 bits (131), Expect = 8e-08
Identities = 69/280 (24%), Positives = 107/280 (38%), Gaps = 36/280 (12%)
Query: 49 NKRQNHSKKESPSRQQSKAHRHR-----HRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQ 103
++R HS + R S+ H HR R +S E H + PSQ+ S
Sbjct: 1626 SERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRSSSERRH-RSPSQRSHRGPS-- 1682
Query: 104 HPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSR 163
E+ CS + +Q G + +P K + +H S R
Sbjct: 1683 ---------ERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSH-RSPARRSHRSPSER 1732
Query: 164 NHLERSLSQSDRSQGQLKRHHPQYERSH-GQYKRSH----------GQSERSHGHSERSH 212
+H S S+ +RHH ERSH +RSH R H SE+SH
Sbjct: 1733 SH--HSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSH 1790
Query: 213 -GHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKD--LIATQRDLIAT 269
SERSH HS RS+ L++ + +R + ++ I+ + +
Sbjct: 1791 HSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSE 1850
Query: 270 QRDLIVTQRDLVA-TERDLINQSGRS-HGQSERHQRYSTG 307
+ L +R + +ER + SG++ H SER R +G
Sbjct: 1851 KSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSG 1890
Score = 48.9 bits (115), Expect = 6e-06
Identities = 65/209 (31%), Positives = 89/209 (42%), Gaps = 41/209 (19%)
Query: 42 TNAEEEKNKRQNHSKKESPSR----QQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPS 97
T+++E KN ++ ++ R K HRH + + +E NH PS
Sbjct: 1495 TSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKD----KLTHKEHNH-------PS 1543
Query: 98 GFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENH 157
++ + P N+ + +E++Q S +H S S+ S P +
Sbjct: 1544 FYRE-RTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSP-----SQRSHCSPSRKN 1597
Query: 158 H---SERS------RNHL---ERSL-SQSDR---SQGQLKRHHPQYERSHGQYKRSH-GQ 200
H SERS RNH ERS S S+R S Q P R H +RSH
Sbjct: 1598 HSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSP 1657
Query: 201 SERSH-GHSERSH-GHSERSH-GHSERSH 226
SERSH SER H S+RSH G SERSH
Sbjct: 1658 SERSHRSSSERRHRSPSQRSHRGPSERSH 1686
Score = 35.4 bits (80), Expect = 0.066
Identities = 44/164 (26%), Positives = 68/164 (41%), Gaps = 27/164 (16%)
Query: 91 KPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSE---------- 140
KP+ SG + Q GQPL +K S + +++KN ++E + +S+
Sbjct: 1456 KPTDSQSGI-AFQTASVGQPLRTVQKDSSS---RSKKNFYRNETSSQESKNLSTPGTRVQ 1511
Query: 141 -------GNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQ 193
G+P K + ++ H E NH ++ R + RH+P +
Sbjct: 1512 ARGRILPGSPVKRTWHRHLKDKLTHKEH--NHPSFYRERTPRGPSERTRHNPSWRNHRSP 1569
Query: 194 YKRSHGQS--ERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQ 235
+RS S R H S+RSH R + HS S S RS SQ
Sbjct: 1570 SERSQRSSLERRHHSPSQRSHCSPSRKN-HSSPSE-RSWRSPSQ 1611
Score = 35.4 bits (80), Expect = 0.066
Identities = 53/202 (26%), Positives = 83/202 (41%), Gaps = 21/202 (10%)
Query: 49 NKRQNHSKKESPSRQQSKAHRHR--HRRGYS---RCRSNSEEGNHDKKPSQKPS--GFKS 101
++R++HS E S+ H RR +S R R + E +H + PS++ S F+
Sbjct: 1778 SERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSH-RSPSERRSHRSFER 1836
Query: 102 GQHPLNGQPLIEQEKCSDNYEAQAEKNQ-GQSEGNQHQSEGNPDKSEESQGQPEENHHSE 160
++ + EK ++ + E+++ SE H S G S P E H
Sbjct: 1837 SHRRISERSHSPSEK---SHLSPLERSRCSPSERRGHSSSGKTCHS------PSERSHRS 1887
Query: 161 RSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSH-GQSERSHGHSERSHGHSERSH 219
S R+ +S RS + RH P R R+H SERS S G + S
Sbjct: 1888 PSGMRQGRTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSR-RSPLKEG-LKYSF 1945
Query: 220 GHSERSHGHSKRSRSQGDLVDT 241
SH S+ ++Q L+ T
Sbjct: 1946 PGERPSHSLSRDFKNQTTLLGT 1967
Score = 33.5 bits (75), Expect = 0.25
Identities = 25/122 (20%), Positives = 43/122 (35%)
Query: 47 EKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPL 106
E++ R+ + SPS + + R R S R +S G PS++ SG
Sbjct: 1835 ERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSERSHRSPSGMRQG 1894
Query: 107 NGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHL 166
+ C + +E G+ G H S + + + + ER + L
Sbjct: 1895 RTSERSHRSSCERTRHSPSEMRPGRPSGRNHCSPSERSRRSPLKEGLKYSFPGERPSHSL 1954
Query: 167 ER 168
R
Sbjct: 1955 SR 1956
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 59.7 bits (143), Expect = 3e-09
Identities = 49/240 (20%), Positives = 97/240 (40%), Gaps = 17/240 (7%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKP 96
K E E+K K H K + + Q + + + + E+ D++ ++
Sbjct: 653 KMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE 712
Query: 97 SGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSE---ESQGQP 153
+ + + + + +E+ + + Q EK Q Q E Q E ++ E E Q P
Sbjct: 713 ESMREREKKMREEEEMMREQ-EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLP 771
Query: 154 EENH---------HSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERS 204
E+ E+ E+ Q ++ +GQ ++ Q E+ GQ ++ GQ E+
Sbjct: 772 EQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKM 831
Query: 205 HGHSERSHGHSERSHGH----SERSHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLI 260
G E+ G E+ G E+ G ++ R Q + + Q + + Q + + Q++ I
Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKI 891
>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
Length = 450
Score = 59.3 bits (142), Expect = 4e-09
Identities = 51/213 (23%), Positives = 87/213 (40%), Gaps = 11/213 (5%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
E++K K+ KK SR + K H+ S S+S E + S+ + K Q
Sbjct: 232 EKKKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQR 291
Query: 105 PLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRN 164
++ KCS + + +E+ + H+ + + E + E SR
Sbjct: 292 KKR-----KKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNREKAKEKPRFLKHESSRE 346
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSER 224
+ S S SD+ + + +H P+ S +R G S RSHG ERS RS G ++
Sbjct: 347 DSKWSHSDSDK-KSRTHKHSPEKRGS----ERKEGSS-RSHGREERSRRSRSRSPGSYKQ 400
Query: 225 SHGHSKRSRSQGDLVDTQSDLIATQRDLIATQK 257
+ R+ G+ ++D + DL +K
Sbjct: 401 RETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEK 433
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/221 (22%), Positives = 83/221 (37%), Gaps = 26/221 (11%)
Query: 5 RKLTLSEKVPPNHPSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESPSRQQ 64
RKL EK RKK F S +K +++ + S+ S S
Sbjct: 226 RKLDRLEK-KKKKKDRKKKKF-QKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESN 283
Query: 65 SKAHR-HRHRRGYSRC--RSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNY 121
+K + R +R ++C +NS+ DK +K + +E S ++
Sbjct: 284 NKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKRK----------------LHEELSSSHH 327
Query: 122 EAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLK 181
EK + + +H+S K S + H S RS G+ +
Sbjct: 328 --NREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEGSSRSHGREE 385
Query: 182 RHHPQYERSHGQYKR--SHGQSERSHGHSERSHGHSERSHG 220
R RS G YK+ + +++R+ G E+S + RSHG
Sbjct: 386 RSRRSRSRSPGSYKQRETRKRAQRNPG-EEQSRRNDSRSHG 425
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 58.2 bits (139), Expect = 9e-09
Identities = 59/235 (25%), Positives = 96/235 (40%), Gaps = 32/235 (13%)
Query: 37 KELEGTNAEEEK----------NKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEG 86
++L+GT K +R+++S+ S SR +S R RH R SR RS S +
Sbjct: 158 EKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRS---RSRHSRK-SRSRSGSSKS 213
Query: 87 NHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKS 146
+H K S+ SG +S + + K + EK++ +S + D++
Sbjct: 214 SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQA 273
Query: 147 EE------SQGQPEENHHSERSRNHLERSLSQSDR---------SQGQLKRHHPQYERSH 191
EE + G+P+ S RS SQ R S+G+ + + RS
Sbjct: 274 EEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Query: 192 GQYKRSHGQSERSHGHSERSHGHSERSHGHS---ERSHGHSKRSRSQGDLVDTQS 243
+ K RS S+ +RS S RS S+RSR +G D+++
Sbjct: 334 SRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKA 388
Score = 55.8 bits (133), Expect = 5e-08
Identities = 50/217 (23%), Positives = 93/217 (42%), Gaps = 21/217 (9%)
Query: 42 TNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEE-----GNHDKKPSQKP 96
+ + + R K SPS+++S++ H + S+ + +EE N K S+ P
Sbjct: 232 SRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSP 291
Query: 97 SGFKSGQ--HPLNGQPLIEQEKC-------SDNYEAQAEKNQGQSEGNQHQSEGNPDKSE 147
S KS + + +E+EK S + +++ +S+G + KS+
Sbjct: 292 SRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSK 351
Query: 148 ESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH 207
+ + + + RSR+ RS S+S+RS+ KR + ++ K+ ++RS
Sbjct: 352 DKRKGRKRSREESRSRS---RSRSKSERSR---KRGSKRDSKAGSSKKKKKEDTDRSQSR 405
Query: 208 SERSHGHSERSHGHSERSHGHSK-RSRSQGDLVDTQS 243
S ER H SE S + S + G +T+S
Sbjct: 406 SPSRSVSKEREHAKSESSQREGRGESENAGTNQETRS 442
Score = 37.7 bits (86), Expect = 0.013
Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 11/151 (7%)
Query: 46 EEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHP 105
++K K + S++ES SR +S++ R R+ S+ S + KK S +S
Sbjct: 351 KDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRS 410
Query: 106 LNGQPLIEQEKCSDNYEAQAEKNQGQSEG---NQHQSEGNPDKSEESQGQPEENHHSERS 162
+ +E+ E+ + +G+SE NQ + S+ P E+ +S
Sbjct: 411 ------VSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS 464
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQ 193
+ RS S+S RS+ + RSH +
Sbjct: 465 ASK-TRSRSKS-RSRSASRSPSRSRSRSHSR 493
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 58.2 bits (139), Expect = 9e-09
Identities = 40/192 (20%), Positives = 83/192 (43%), Gaps = 2/192 (1%)
Query: 44 AEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQ 103
A E+ + ++ K++S +A +H + R SR R + +++ + + S K G+
Sbjct: 12 APEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGR 71
Query: 104 HPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSR 163
+ ++ K ++ + + ++G+ N ++ + K +E + +H RSR
Sbjct: 72 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 131
Query: 164 NHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSE 223
RS S+ +R + + + + RS + ++ R RS S H H
Sbjct: 132 ERRHRSRSR-ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 190
Query: 224 RSHGHSKRSRSQ 235
RS + RSRS+
Sbjct: 191 RSRSRT-RSRSR 201
Score = 48.5 bits (114), Expect = 8e-06
Identities = 54/222 (24%), Positives = 82/222 (36%), Gaps = 30/222 (13%)
Query: 11 EKVPPNHPSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRH 70
EK P+ +K+ + + +S + + + E K K N +K SR +SK R
Sbjct: 14 EKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHR-SRSRSKEGRR 72
Query: 71 RHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQG 130
+ S + SEE N + S K G+ LN E D ++ + K+
Sbjct: 73 HESKDKSSKKHKSEEHNDKEHSSDK------GRERLN-----SSENGEDRHKRKERKS-- 119
Query: 131 QSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERS 190
S G H S+ + E H RSR ER S+S + + R + +
Sbjct: 120 -SRGRSH-----------SRSRSRERRHRSRSR---ERKKSRSRSRERKKSRSRSRERKK 164
Query: 191 HGQYKRSHGQSERSHGHSERSHGHSERSHGHS-ERSHGHSKR 231
R + RS S H H RS + RS KR
Sbjct: 165 SRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKR 206
Score = 33.1 bits (74), Expect = 0.33
Identities = 30/126 (23%), Positives = 56/126 (44%), Gaps = 15/126 (11%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQSKAHR----------HRHR-RGYSRCRSNSEE 85
K+ + E +K++ ++ +K+S SR + + R HRHR R SR RS S +
Sbjct: 143 KKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRD 202
Query: 86 GNHDKKPSQKPSGF-KSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPD 144
KK +KP F +S + P + D EA A + + + + + + +
Sbjct: 203 R---KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVE 259
Query: 145 KSEESQ 150
K ++ +
Sbjct: 260 KQKQQE 265
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 57.8 bits (138), Expect = 1e-08
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 15/188 (7%)
Query: 60 PSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSD 119
P RQ S A R G S +++ EG+ ++ +Q SG H +G ++ +
Sbjct: 1050 PRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSG-----HGQDGPHQQSHQESAR 1104
Query: 120 NYEAQAEKNQGQ---SEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRS 176
++ G QSE ++ S G+ + +HH E++R+ S SQ +
Sbjct: 1105 DWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHH-EQARDSSRHSASQEGQD 1163
Query: 177 QGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHS-KRSRSQ 235
R HP R G+ H QS GHS H H+ S G S+ SHG S RS S+
Sbjct: 1164 T---IRAHPGSRRG-GRQGSHHEQSVDRSGHSGSHHSHT-TSQGRSDASHGQSGSRSASR 1218
Query: 236 GDLVDTQS 243
D QS
Sbjct: 1219 QTRKDKQS 1226
Score = 55.5 bits (132), Expect = 6e-08
Identities = 53/207 (25%), Positives = 82/207 (39%), Gaps = 28/207 (13%)
Query: 43 NAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSG 102
++E+ + + S+ S Q+ H RH R + R+ G+ S + SG
Sbjct: 955 HSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRA----GHGHSADSSRQSGTPHA 1010
Query: 103 QHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERS 162
+ GQ E QA + G+ G++HQ D S S + + R
Sbjct: 1011 ETSSGGQAASSHE--------QARSSPGERHGSRHQQSA--DSSRHSGIPRRQASSAVRD 1060
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQ---YKRSHGQSER--SHGHSERS------ 211
H S SQ+ S+G + Q HGQ +++SH +S R S G S RS
Sbjct: 1061 SGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQ 1120
Query: 212 ---HGHSERSHGHSERSHGHSKRSRSQ 235
H SE +HG + S G + S +
Sbjct: 1121 VSTHEQSESAHGRTRTSTGRRQGSHHE 1147
Score = 55.5 bits (132), Expect = 6e-08
Identities = 50/206 (24%), Positives = 81/206 (39%), Gaps = 24/206 (11%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEE--GNHDKKPSQKPSGFKSG 102
+ E + + + ES SR + R + R G RS+ E+ + S + SG +
Sbjct: 1599 DSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHA 1658
Query: 103 QHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSE------------ESQ 150
+ GQ QE QA + G+ G++HQ + +S
Sbjct: 1659 ETSSGGQAASSQE--------QARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSG 1710
Query: 151 GQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERS-HGQYKRSHGQSERSHGHSE 209
+ + S H E S +QS + GQ H ++ S GQ G+S S +
Sbjct: 1711 NRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRS-GSFLYQV 1769
Query: 210 RSHGHSERSHGHSERSHGHSKRSRSQ 235
+H SE +HG + S G +RSR +
Sbjct: 1770 STHEQSESAHGRTGPSTGGRQRSRHE 1795
Score = 55.1 bits (131), Expect = 8e-08
Identities = 53/212 (25%), Positives = 86/212 (40%), Gaps = 25/212 (11%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHR------HRHRRGYSRCRSNSEEGNHDKKPS 93
+G++ ++ + + E S S+ HR RH + R G+
Sbjct: 3211 QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADR 3270
Query: 94 QKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQP 153
+ SG + + GQ E QA + G+ G++HQ + D S S
Sbjct: 3271 SRQSGTRHAETSSGGQAASSHE--------QARSSPGERHGSRHQQ--SADSSRHSGIPR 3320
Query: 154 EENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQ---YKRSHGQS--ERSHGHS 208
+ + R H S SQ+ S+G + Q HGQ +++SH +S +RS G S
Sbjct: 3321 GQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRS 3380
Query: 209 ERSHG--HSERSHGHSERSHGHSKRS--RSQG 236
RS + +H SE +HG ++ S R QG
Sbjct: 3381 GRSGSFLYQVSTHEQSESAHGRTRTSTGRRQG 3412
Score = 54.7 bits (130), Expect = 1e-07
Identities = 52/206 (25%), Positives = 83/206 (40%), Gaps = 19/206 (9%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
+ +++E + S S + + S + RH + R G+ S + SG
Sbjct: 948 QDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGT 1007
Query: 100 KSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHS 159
+ GQ E QA + G+ G++HQ + D S S + +
Sbjct: 1008 PHAETSSGGQAASSHE--------QARSSPGERHGSRHQQ--SADSSRHSGIPRRQASSA 1057
Query: 160 ERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQ---YKRSHGQSER--SHGHSERSHG- 213
R H S SQ+ S+G + Q HGQ +++SH +S R S G S RS
Sbjct: 1058 VRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSF 1117
Query: 214 -HSERSHGHSERSHGHSKRS--RSQG 236
+ +H SE +HG ++ S R QG
Sbjct: 1118 IYQVSTHEQSESAHGRTRTSTGRRQG 1143
Score = 54.3 bits (129), Expect = 1e-07
Identities = 60/229 (26%), Positives = 97/229 (42%), Gaps = 43/229 (18%)
Query: 40 EGTNAEEEKNKRQNHSKKE-----SPSRQQSKAHRHRHRRGYSRCRSNSEE--GNHDKKP 92
+G++ ++ + Q HS+ S SR + + + R G RS+ E+ G+
Sbjct: 617 QGSSVSQDSDS-QGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAD 675
Query: 93 SQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQ 152
S + SG + Q+ +GQ E QA + G+ G++HQ + + D S S
Sbjct: 676 SSRKSGTRHTQNSSSGQAASSHE--------QARSSAGERHGSRHQLQ-SADSSRHSGTG 726
Query: 153 PEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQ---YKRSHGQS--ERSHGH 207
+ + R H S SQ+ S+G + Q HGQ +++SH +S +RS
Sbjct: 727 HGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGER 786
Query: 208 SERS---------HGHSERSHG------------HSERSHGHSKRSRSQ 235
S RS H SE SHG H E++ +S+ S SQ
Sbjct: 787 SRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQ 835
Score = 54.3 bits (129), Expect = 1e-07
Identities = 52/207 (25%), Positives = 83/207 (40%), Gaps = 28/207 (13%)
Query: 43 NAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSG 102
++E+ + + S+ S Q+ H RH R + R+ G+ + SG +
Sbjct: 3224 HSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRA----GHGHSADRSRQSGTRHA 3279
Query: 103 QHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERS 162
+ GQ E QA + G+ G++HQ D S S + + R
Sbjct: 3280 ETSSGGQAASSHE--------QARSSPGERHGSRHQQSA--DSSRHSGIPRGQASSAVRD 3329
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQ---YKRSHGQS--ERSHGHSERS------ 211
H S SQ+ S+G + Q HGQ +++SH +S +RS G S RS
Sbjct: 3330 SRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQ 3389
Query: 212 ---HGHSERSHGHSERSHGHSKRSRSQ 235
H SE +HG + S G + S +
Sbjct: 3390 VSTHEQSESAHGRTRTSTGRRQGSHHE 3416
Score = 51.6 bits (122), Expect = 9e-07
Identities = 67/272 (24%), Positives = 97/272 (35%), Gaps = 45/272 (16%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHR---------RGYSRCRSNSEEGNHDKKPSQKPSGFKS 101
RQ ++S R H H G S RS S + DK+ S
Sbjct: 1176 RQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGS 1235
Query: 102 GQHPL------NGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEE 155
H + + QE+ S + + ++QG S SE + D SE G
Sbjct: 1236 RHHEAASWADSSRHSQVGQEQSSGS---RTSRHQGSSVSQDSDSERHSDDSERLSGSASR 1292
Query: 156 NHHSERSRNHLERSLSQSDRSQGQLKRHHPQYER----SHGQYKRSHGQSERSHGHSERS 211
NHH S R Q + HP + + SHG S QS H S S
Sbjct: 1293 NHHG-------------SSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESS-S 1338
Query: 212 HGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQR 271
HG + SH + S G SR Q ++ I ++ A + + R +Q
Sbjct: 1339 HGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRD---SGHRGSSGSQ- 1394
Query: 272 DLIVTQRDLVATERDLINQSGRSHGQSERHQR 303
VT + + + D QS +HGQ+ HQ+
Sbjct: 1395 ---VTNSEGHSEDSD--TQSVSAHGQAGPHQQ 1421
Score = 51.6 bits (122), Expect = 9e-07
Identities = 56/217 (25%), Positives = 86/217 (39%), Gaps = 21/217 (9%)
Query: 50 KRQNHSKKESPSRQQSKAHRHRHRRG----YSRCRSNSEEGNHDK-KPSQKPSGFKSGQH 104
+R + S+ +S SR S+ R+ + G +S R + D + SQ G SG
Sbjct: 1850 ERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPR 1909
Query: 105 PLNGQ-PLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSR 163
Q + Q+ S + +E+ G + N S ++S + P +H
Sbjct: 1910 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAW--EQSRDGSRHPGSHHEDRAGH 1967
Query: 164 NHLERSLSQS------DRSQGQLKRHHPQYERSHGQYKRSHG--QSERSHGHSERSHGHS 215
H S QS S+GQ H Q S G+ SH QS S HS HG +
Sbjct: 1968 GHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQA 2027
Query: 216 E---RSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQ 249
R GH R + S+ S S+G D+ + ++ Q
Sbjct: 2028 SSAVRDSGH--RGYSGSQASDSEGHSEDSDTQSVSAQ 2062
Score = 51.2 bits (121), Expect = 1e-06
Identities = 51/217 (23%), Positives = 81/217 (37%), Gaps = 20/217 (9%)
Query: 41 GTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFK 100
G A + R + ++ QQS G+ + S + H + S +
Sbjct: 2313 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSE 2372
Query: 101 SGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQ-------------HQSEGNPDKSE 147
+ Q + + + ++ E +G+S G QSE ++
Sbjct: 2373 GHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTG 2432
Query: 148 ESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH 207
S G + +HH + +R+ S SQ +GQ H S G+ + Q GH
Sbjct: 2433 TSTGGRQGSHHKQ-ARDSSRHSTSQ----EGQDTIHGHPGSSSGGRQGSHYEQLVDRSGH 2487
Query: 208 SERSHGHSERSHGHSERSHGHS-KRSRSQGDLVDTQS 243
S H H+ S G S+ SHGHS RS S+ D QS
Sbjct: 2488 SGSHHSHTT-SQGRSDASHGHSGSRSASRQTRNDEQS 2523
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/210 (25%), Positives = 85/210 (40%), Gaps = 18/210 (8%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
+G++ ++ + ++ E S S+ H H R SR S + + + S S
Sbjct: 1266 QGSSVSQDSDSERHSDDSERLSGSASRNH-HGSSREQSRDGSRHPGFHQEDRASHGHSAD 1324
Query: 100 KSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHS 159
S Q + + ++E QA + G+ G++HQ D S S + +
Sbjct: 1325 SSRQSGTHHTESSSHGQAVSSHE-QARSSPGERHGSRHQQSA--DSSRHSGIGHRQASSA 1381
Query: 160 ERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQ---YKRSH-----GQSERSHGHSER- 210
R H S SQ S+G + Q +HGQ +++SH GQS S G S
Sbjct: 1382 VRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSF 1441
Query: 211 -----SHGHSERSHGHSERSHGHSKRSRSQ 235
SH SE +HG + S G + SR +
Sbjct: 1442 LYQVSSHEQSESTHGQTAPSTGGRQGSRHE 1471
Score = 50.8 bits (120), Expect = 2e-06
Identities = 65/236 (27%), Positives = 88/236 (37%), Gaps = 40/236 (16%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHR---------RGYSRCRSNSEEGNHDKKPSQKPSGFKS 101
RQ +++S R H H RG S RS S + +DK+ S S S
Sbjct: 2149 RQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRK-TYDKEQSGDGSRH-S 2206
Query: 102 GQHPLNGQPLIEQEKCSDNYEAQAE-----KNQGQSEGNQHQSEGNPDKSEESQGQPEEN 156
G H + + S + Q+ + +G S SEG+ + SE G N
Sbjct: 2207 GSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRN 2266
Query: 157 HHS---ERSRN--------HLERS-LSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERS 204
HH E+SR+ H +R+ S S Q HH + S GQ SH Q+ S
Sbjct: 2267 HHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAE-NSSGGQAASSHEQARSS 2325
Query: 205 HGHSERSHG--------HSERSHGHSE---RSHGHSKRSRSQGDLVDTQSDLIATQ 249
G SH HS HG + R GH S SQ + S+ TQ
Sbjct: 2326 AGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQ 2381
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/234 (26%), Positives = 85/234 (36%), Gaps = 36/234 (15%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHR---------RGYSRCRSNSEEGNHDKKPSQKPSGFKS 101
RQ ++S R H H RG S RS S + +D++ S
Sbjct: 3445 RQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWS 3504
Query: 102 GQHPLNGQPLIEQEKCSDNYEA---QAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHH 158
H + Q + S ++ + +NQG S S+G+ + SE G NH
Sbjct: 3505 HHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHR 3564
Query: 159 S---ERSRN--------HLERS-LSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHG 206
E+SR+ H +R+ S S Q HH + S GQ SH Q+ S G
Sbjct: 3565 GSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAE-NSSGGQAASSHEQARSSAG 3623
Query: 207 HSERSHG--------HSERSHGHSE---RSHGHSKRSRSQGDLVDTQSDLIATQ 249
SH HS HG + R GH S SQ + S+ TQ
Sbjct: 3624 ERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQ 3677
Score = 50.1 bits (118), Expect = 3e-06
Identities = 53/203 (26%), Positives = 76/203 (37%), Gaps = 17/203 (8%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHRRG-----YSRCRSNSEEGNHDKKPSQKPSGFKSGQHP 105
R H SRQ H G + + RS+ E + + S SG
Sbjct: 3261 RAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPR 3320
Query: 106 LNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNH 165
+ + + +QA ++G SE + QS S Q P + H E +R
Sbjct: 3321 GQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSV-----SGHGQAGPHQQSHQESAR-- 3373
Query: 166 LERSLSQSDRSQGQLKR--HHPQYERSHGQYKRSHGQSERSHGHSER-SHGHSERSHGHS 222
+RS +S RS L + H Q E +HG+ + S G+ + SH R S HS G
Sbjct: 3374 -DRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQD 3432
Query: 223 E-RSHGHSKRSRSQGDLVDTQSD 244
R H S R QG + D
Sbjct: 3433 TIRGHPGSSRRGRQGSHYEQSVD 3455
Score = 49.7 bits (117), Expect = 3e-06
Identities = 50/197 (25%), Positives = 77/197 (39%), Gaps = 13/197 (6%)
Query: 47 EKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPL 106
E + + S+ + QS+ R R+G S + + EG+ + S++ SG S H
Sbjct: 2860 EASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSED--SERWSGSASRNHHG 2917
Query: 107 NGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSR--- 163
+ Q + + G S + QS G S GQ +H RS
Sbjct: 2918 SAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQS-GTRHTQTSSGGQAASSHEQARSSAGE 2976
Query: 164 ---NHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHG 220
+H ++S + S R G R G S Q+ + GHSE S S +HG
Sbjct: 2977 RHGSHHQQS-ADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHG 3035
Query: 221 HS---ERSHGHSKRSRS 234
+ ++SH S R RS
Sbjct: 3036 QAGSHQQSHQESARGRS 3052
Score = 49.3 bits (116), Expect = 4e-06
Identities = 44/189 (23%), Positives = 72/189 (38%), Gaps = 21/189 (11%)
Query: 63 QQSKAHRHRHRRGYSRCRSNSEEGNHDK--KPSQKPSGFKSGQHPLNGQPLIEQEKCSDN 120
Q S + G +R + +G+H + + S + S + GQ + P + +
Sbjct: 1120 QVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGS 1179
Query: 121 YEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQL 180
+ Q+ G S G+ H + +S+ S GQ S ++R + D S+
Sbjct: 1180 HHEQSVDRSGHS-GSHHSHTTSQGRSDASHGQSGSRSASRQTR----KDKQSGDGSRHSG 1234
Query: 181 KRHHP--------------QYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSH 226
RHH Q + S + R G S SER SER G + R+H
Sbjct: 1235 SRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNH 1294
Query: 227 GHSKRSRSQ 235
S R +S+
Sbjct: 1295 HGSSREQSR 1303
Score = 49.3 bits (116), Expect = 4e-06
Identities = 41/199 (20%), Positives = 75/199 (37%), Gaps = 17/199 (8%)
Query: 47 EKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKS----- 101
E + R S+ + +S + R+G S + EG+ + + S ++
Sbjct: 1563 EPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSA 1622
Query: 102 ---GQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHH 158
+H ++++ S + A++ + G E+++ P E H
Sbjct: 1623 REQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHG 1682
Query: 159 SERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERS 218
S H + + S +D G +R G S Q+ S GHSE S S +
Sbjct: 1683 SR----HQQSADSSTDSGTG--RRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSA 1736
Query: 219 HGHS---ERSHGHSKRSRS 234
HG + ++SH S R +S
Sbjct: 1737 HGQAGPHQQSHQESTRGQS 1755
Score = 49.3 bits (116), Expect = 4e-06
Identities = 50/189 (26%), Positives = 72/189 (38%), Gaps = 23/189 (12%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHRRG-----YSRCRSNSEE--GNHDKKP--SQKPSGFKS 101
R H SRQ H G + + RS++ E G+H ++ S + SG
Sbjct: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 2348
Query: 102 GQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSER 161
GQ + + +QA ++G SE + QS S Q P + H E
Sbjct: 2349 GQ----ASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSV-----SAHGQAGPHQQSHQES 2399
Query: 162 SRNHLERSLSQSDRSQGQLKR--HHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSH 219
+R RS +S RS L + H Q E +HG+ S G + SH R S
Sbjct: 2400 TRG---RSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQ 2456
Query: 220 GHSERSHGH 228
+ HGH
Sbjct: 2457 EGQDTIHGH 2465
Score = 48.9 bits (115), Expect = 6e-06
Identities = 51/230 (22%), Positives = 92/230 (40%), Gaps = 43/230 (18%)
Query: 37 KELEG---TNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRC--RSNSEEGNHDKK 91
KE +G T+ EEE K ++S K+ ++ ++ +R R + ++EEG +D +
Sbjct: 159 KERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYE 218
Query: 92 PSQK------PSGFKSGQHPLNGQP------LIEQEKCSDNYEAQAEKNQGQSEGNQHQ- 138
+ + SG + + + + L+E+ K + + K+ Q ++H+
Sbjct: 219 NTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHEN 278
Query: 139 ----------------SEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKR 182
S + D+ E + E H SRNH + QS R
Sbjct: 279 TSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQS--------R 330
Query: 183 HHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRS 232
++ RSH + + SHG S S S H + S G + SH ++ S
Sbjct: 331 DGSRHPRSHDEDRASHGHSADSSRQSGTRHAETS-SRGQTASSHEQARSS 379
Score = 48.9 bits (115), Expect = 6e-06
Identities = 58/220 (26%), Positives = 77/220 (35%), Gaps = 28/220 (12%)
Query: 53 NHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLI 112
+HS S R + +H H R SR N E+ + S S + +G +
Sbjct: 2491 HHSHTTSQGRSDA-SHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQV 2549
Query: 113 EQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHH----------SERS 162
Q + + +N G S S+G+ + SE G NHH S
Sbjct: 2550 GQGQSEG---PRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHP 2606
Query: 163 RNHLERSLSQ--SDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHG------- 213
R+H E S S Q H Q S GQ SH Q+ S G SH
Sbjct: 2607 RSHQEDRAGHGHSADSSRQSGTRHTQTS-SGGQAASSHEQARSSAGERHGSHHQQSADSS 2665
Query: 214 -HSERSHGHSE---RSHGHSKRSRSQGDLVDTQSDLIATQ 249
HS HG + R GH S SQ + S+ TQ
Sbjct: 2666 RHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ 2705
Score = 48.9 bits (115), Expect = 6e-06
Identities = 51/198 (25%), Positives = 73/198 (36%), Gaps = 11/198 (5%)
Query: 47 EKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPL 106
E + + S+ + QS+ R R+G S + + EG+ + S++ SG S H
Sbjct: 3184 EASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH--SEDSERWSGSASRNHRG 3241
Query: 107 NGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERS---R 163
+ Q + G S QS G S GQ +H RS
Sbjct: 3242 SVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQS-GTRHAETSSGGQAASSHEQARSSPGE 3300
Query: 164 NHLERSLSQSD--RSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGH 221
H R +D R G + R + S Q+ S GHSE S S HG
Sbjct: 3301 RHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQ 3360
Query: 222 S---ERSHGHSKRSRSQG 236
+ ++SH S R RS G
Sbjct: 3361 AGPHQQSHQESARDRSGG 3378
Score = 48.1 bits (113), Expect = 1e-05
Identities = 50/199 (25%), Positives = 76/199 (38%), Gaps = 13/199 (6%)
Query: 47 EKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPL 106
E + + + S+ + QS R +G S + + +G+ + S++ SG S H
Sbjct: 3508 EASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSED--SERWSGSASRNHRG 3565
Query: 107 NGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSR--- 163
+ Q + G S + QS G S GQ +H RS
Sbjct: 3566 SAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQS-GTHHAENSSGGQAASSHEQARSSAGE 3624
Query: 164 ---NHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHG 220
+H ++S + S R G R G S Q+ S GHSE S S +HG
Sbjct: 3625 RHGSHHQQS-ADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHG 3683
Query: 221 HS---ERSHGHSKRSRSQG 236
+ ++SH S R RS G
Sbjct: 3684 QAGPHQQSHQESTRGRSAG 3702
Score = 48.1 bits (113), Expect = 1e-05
Identities = 51/217 (23%), Positives = 79/217 (36%), Gaps = 24/217 (11%)
Query: 59 SPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPL--IEQEK 116
S Q S + H ++ + G H + + G +G+ +G L + +
Sbjct: 3659 SSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHE 3718
Query: 117 CSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ-GQPEENHHSERSRNHLERSLSQSDR 175
S++ +A + G +G++H+ + + SQ GQ H R + S +
Sbjct: 3719 QSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSV 3778
Query: 176 SQGQLKRHHPQYERSHGQYKRSHGQS-----------ERSHGHSERSHG--HSERS---- 218
+ H + S G+ SHGQS E G R G H E S
Sbjct: 3779 DRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQAD 3838
Query: 219 -HGHSERSHGHS---KRSRSQGDLVDTQSDLIATQRD 251
HS+ G S +RSR QG V SD A D
Sbjct: 3839 SSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPED 3875
Score = 47.8 bits (112), Expect = 1e-05
Identities = 50/212 (23%), Positives = 82/212 (38%), Gaps = 32/212 (15%)
Query: 42 TNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKS 101
T++ E+NK S+ S + S+ +R RH N+ + + ++K G +
Sbjct: 247 TDSLLEENKIYERSRS-SDGKSSSQVNRSRHE--------NTSQVPLQESRTRKRRGSR- 296
Query: 102 GQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSER 161
+ Q++ S+ + +E++ G + N H S ++S + P +
Sbjct: 297 ----------VSQDRDSEGHSEDSERHSGSASRNHHGSAW--EQSRDGSRHPRSHDEDRA 344
Query: 162 SRNHLERSLSQSDR------SQGQLKRHHPQYERSHGQYKRS-HGQSERSHGHSERSHGH 214
S H S QS S+GQ H Q S G+ S H QS S HS G
Sbjct: 345 SHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQ 404
Query: 215 SERS---HGHSERSHGHSKRSRSQGDLVDTQS 243
+ + GH S + S + DTQS
Sbjct: 405 ASSAVSDRGHRGSSGSQASDSEGHSENSDTQS 436
Score = 47.8 bits (112), Expect = 1e-05
Identities = 61/280 (21%), Positives = 92/280 (32%), Gaps = 50/280 (17%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKA---HRHRHRRGYSRCRSNSEEGNHDKKPSQKP 96
+G++ E+ N+ + S + Q ++ H R SR N E+ + S
Sbjct: 528 QGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSR 587
Query: 97 SGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEEN 156
S Q + + Q + S + +NQG S S+G+ + SE G N
Sbjct: 588 HHEASSQADSSRHSQVGQGQSSG---PRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRN 644
Query: 157 HHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHS-------- 208
HH S + Q + HP RSH + HGHS
Sbjct: 645 HHG-------------SAQEQSRDGSRHP----------RSHHEDRAGHGHSADSSRKSG 681
Query: 209 -----ERSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQ 263
S G + SH + S G SR Q D+ + +D +
Sbjct: 682 TRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRD--SGH 739
Query: 264 RDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSERHQR 303
R +Q D D QS HGQ+ HQ+
Sbjct: 740 RGSSGSQ------ATDSEGHSEDSDTQSVSGHGQAGHHQQ 773
Score = 47.4 bits (111), Expect = 2e-05
Identities = 52/198 (26%), Positives = 74/198 (37%), Gaps = 22/198 (11%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHRRG-----YSRCRSNSEE--GNHDK---KPSQKPSGFK 100
R H SRQ H RG + + RS++ E G+H + S + SG
Sbjct: 1964 RAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIG 2023
Query: 101 SGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSE 160
GQ + +QA ++G SE + QS S + + P + H E
Sbjct: 2024 HGQ----ASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSV-----SAQGKAGPHQQSHKE 2074
Query: 161 RSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSH-GHSERSHGHSERSH 219
+R S +S Q+ H Q E +HGQ S G + SH ++ S HS
Sbjct: 2075 SARGQSGESSGRSGSFLYQVSTHE-QSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQE 2133
Query: 220 GHSE-RSHGHSKRSRSQG 236
G R H R QG
Sbjct: 2134 GQDTIRGHPGPSRGGRQG 2151
Score = 46.6 bits (109), Expect = 3e-05
Identities = 44/173 (25%), Positives = 69/173 (39%), Gaps = 15/173 (8%)
Query: 63 QQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYE 122
Q S A R RGYS +++ EG+ + +Q S +GQ Q+ ++
Sbjct: 2998 QASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA--------HGQAGSHQQSHQESAR 3049
Query: 123 AQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKR 182
++ + G S +Q + ++SE S G + + H + D S+ +
Sbjct: 3050 GRSGETSGHSGSFLYQVSTH-EQSESSHGWTGPSTRGRQGSRHEQAQ----DSSRHSASQ 3104
Query: 183 HHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQ 235
+ R H R G+ H HS S GHS H H+ S G S SR Q
Sbjct: 3105 YGQDTIRGHPGSSRG-GRQGYHHEHSVDSSGHSGSHHSHT-TSQGRSDASRGQ 3155
Score = 46.2 bits (108), Expect = 4e-05
Identities = 47/177 (26%), Positives = 70/177 (39%), Gaps = 23/177 (12%)
Query: 63 QQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYE 122
Q S A R RGYS +++ EG+ + +Q S +GQ Q+ ++
Sbjct: 2674 QASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA--------HGQAGSHQQSHQESAR 2725
Query: 123 AQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQ--- 179
++ + G S +Q + ++SE S G + + H E++ S S Q
Sbjct: 2726 GRSGETSGHSGSFLYQVSTH-EQSESSHGWTGPSTRGRQGSRH-EQAQDSSRHSASQDGQ 2783
Query: 180 -LKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQ 235
R HP R G+ H HS S GHS H H+ S G S SR Q
Sbjct: 2784 DTIRGHPGSSRG--------GRQGYHHEHSVDSSGHSGSHHSHT-TSQGRSDASRGQ 2831
Score = 46.2 bits (108), Expect = 4e-05
Identities = 55/214 (25%), Positives = 79/214 (36%), Gaps = 23/214 (10%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNS---EEGNHD--KKPSQKPSGFKSGQHP 105
R + S+ +S SR S+ R+ + G S S E H + SQ G G
Sbjct: 2824 RSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRR 2883
Query: 106 LNGQ-PLIEQEKCSDNYEAQAEKNQGQSEGNQHQS------EGNPDKSEESQGQPEENHH 158
Q + Q+ S+ + +E+ G + N H S +G+ + + H
Sbjct: 2884 SRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHS 2943
Query: 159 SERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERS 218
++ SR R S S GQ H Q S G+ SH H S S HS
Sbjct: 2944 ADSSRQSGTRHTQTS--SGGQAASSHEQARSSAGERHGSH------HQQSADSSRHSGIG 2995
Query: 219 HGHSE---RSHGHSKRSRSQGDLVDTQSDLIATQ 249
HG + R GH S SQ + S+ TQ
Sbjct: 2996 HGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ 3029
Score = 46.2 bits (108), Expect = 4e-05
Identities = 58/225 (25%), Positives = 90/225 (40%), Gaps = 28/225 (12%)
Query: 36 YKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQK 95
++ G+ A + + ++ + + Q+ +H+ H+ +R RS G+ Q
Sbjct: 3008 HRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQES-ARGRSGETSGHSGSFLYQV 3066
Query: 96 PSGFKS-GQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPE 154
+ +S H G P + S + +AQ S+ Q G+P S +G +
Sbjct: 3067 STHEQSESSHGWTG-PSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSS---RGGRQ 3122
Query: 155 ENHH------SERSRNHLERSLSQ--SDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHG 206
HH S S +H + SQ SD S+GQ RS + R+ QS S
Sbjct: 3123 GYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQ------SGSRSASRTTRNEEQSGDSSR 3176
Query: 207 HSERSHGHSERSHG----HSERSHGHS---KRSRSQGDLVDTQSD 244
HS H H +H HS+ G S +RSR QG V SD
Sbjct: 3177 HSVSRH-HEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSD 3220
Score = 45.8 bits (107), Expect = 5e-05
Identities = 48/214 (22%), Positives = 71/214 (33%), Gaps = 14/214 (6%)
Query: 42 TNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHD-KKPSQKPSGFK 100
T ++ + + S S SR + R +S R + + D + SQ G
Sbjct: 874 TTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQS 933
Query: 101 SGQHPLNGQ-PLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHS 159
G Q + Q+ S+ + +E+ G + N S ++S P +H
Sbjct: 934 EGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSA--QEQSRHGSRHPRSHHED 991
Query: 160 ERSRNHLERSLSQSDR------SQGQLKRHHPQYERS----HGQYKRSHGQSERSHGHSE 209
H S QS S GQ H Q S HG + S R G
Sbjct: 992 RAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPR 1051
Query: 210 RSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQS 243
R + R GH S + S + DTQS
Sbjct: 1052 RQASSAVRDSGHWGSSGSQASDSEGHSEESDTQS 1085
Score = 45.8 bits (107), Expect = 5e-05
Identities = 58/224 (25%), Positives = 87/224 (38%), Gaps = 48/224 (21%)
Query: 59 SPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCS 118
S Q AH R RS E+ + S + S + GQ + G P +
Sbjct: 1770 STHEQSESAHGRTGPSTGGRQRSRHEQA----RDSSRHSASQEGQDTIRGHPGSSRGGRQ 1825
Query: 119 DNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRN-------------- 164
++ Q+ + G S G+ H + ++S+ S+GQ S ++RN
Sbjct: 1826 GSHYEQSVDSSGHS-GSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSR 1884
Query: 165 HLERSLSQSDRSQ----GQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSH---GHSER 217
H E S S++D S+ GQ + P+ R+ G S Q S GHSE S G + R
Sbjct: 1885 HHEAS-SRADSSRHSQVGQGQSSGPRTSRNQGS---SVSQDSDSQGHSEDSERWSGSASR 1940
Query: 218 SH-----------------GHSERS-HGHSKRSRSQGDLVDTQS 243
+H H +R+ HGHS S Q T+S
Sbjct: 1941 NHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTES 1984
Score = 45.8 bits (107), Expect = 5e-05
Identities = 49/197 (24%), Positives = 75/197 (38%), Gaps = 13/197 (6%)
Query: 47 EKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPL 106
E + R + S + QS+ R G S + + +G+ + S++ SG S H
Sbjct: 2536 EASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSED--SERWSGSASRNHHG 2593
Query: 107 NGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSR--- 163
+ Q + + G S + QS G S GQ +H RS
Sbjct: 2594 SAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQS-GTRHTQTSSGGQAASSHEQARSSAGE 2652
Query: 164 ---NHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHG 220
+H ++S + S R G R G S Q+ + GHSE S S +HG
Sbjct: 2653 RHGSHHQQS-ADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHG 2711
Query: 221 HS---ERSHGHSKRSRS 234
+ ++SH S R RS
Sbjct: 2712 QAGSHQQSHQESARGRS 2728
Score = 45.4 bits (106), Expect = 6e-05
Identities = 60/256 (23%), Positives = 93/256 (36%), Gaps = 73/256 (28%)
Query: 50 KRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFK-----SGQH 104
K +H K E ++++K +R +R S R N+ +GN + S + +G K S +
Sbjct: 103 KHSHHDKHEDNKQEENKENR---KRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKK 159
Query: 105 PLNG-QPLIEQEKCSDNYEAQAEKNQGQSE------GNQHQSEGNPDKSEESQG------ 151
G P +E+ N+ ++K + ++E + SE +K + +G
Sbjct: 160 ERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYEN 219
Query: 152 ------------------------------QPEENHHSERSRNHLERSLSQSDRSQGQLK 181
EEN ERSR+ +S SQ +RS+ +
Sbjct: 220 TGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENT 279
Query: 182 RHHPQYERSHGQYKRSHGQSER-SHGHSERSHGHS---------------------ERSH 219
P E + + S +R S GHSE S HS RSH
Sbjct: 280 SQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSH 339
Query: 220 GHSERSHGHSKRSRSQ 235
SHGHS S Q
Sbjct: 340 DEDRASHGHSADSSRQ 355
Score = 45.4 bits (106), Expect = 6e-05
Identities = 48/206 (23%), Positives = 73/206 (35%), Gaps = 25/206 (12%)
Query: 53 NHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHP------- 105
+H + SR + RG+ +G+H ++ + SG H
Sbjct: 821 HHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDR-SGHSGSHHSHTTSQGR 879
Query: 106 ---LNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ---GQPEENHHS 159
GQ + E Q+ S H++ + D S SQ GQ E + S
Sbjct: 880 SDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTS 939
Query: 160 ERSRNHL------ERSLSQSDRSQGQLKRHH---PQYERSHG-QYKRSHGQSERSHGHSE 209
R + + E S+R G R+H Q + HG ++ RSH + HGHS
Sbjct: 940 RRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSA 999
Query: 210 RSHGHSERSHGHSERSHGHSKRSRSQ 235
S S H + S G + S Q
Sbjct: 1000 DSSRQSGTPHAETS-SGGQAASSHEQ 1024
Score = 45.4 bits (106), Expect = 6e-05
Identities = 57/225 (25%), Positives = 89/225 (39%), Gaps = 28/225 (12%)
Query: 36 YKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQK 95
++ G+ A + + ++ + + Q+ +H+ H+ +R RS G+ Q
Sbjct: 2684 HRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQES-ARGRSGETSGHSGSFLYQV 2742
Query: 96 PSGFKS-GQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPE 154
+ +S H G P + S + +AQ S+ Q G+P S +G +
Sbjct: 2743 STHEQSESSHGWTG-PSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSS---RGGRQ 2798
Query: 155 ENHH------SERSRNHLERSLSQ--SDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHG 206
HH S S +H + SQ SD S+GQ RS + R+ QS
Sbjct: 2799 GYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQ------SGSRSASRTTRNEEQSGDGSR 2852
Query: 207 HSERSHGHSERSHG----HSERSHGHS---KRSRSQGDLVDTQSD 244
HS H H +H HS+ G S +RSR QG V SD
Sbjct: 2853 HSGSRH-HEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSD 2896
Score = 45.4 bits (106), Expect = 6e-05
Identities = 48/197 (24%), Positives = 74/197 (37%), Gaps = 22/197 (11%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFK--SGQHPLNG 108
RQ + + S H H S+ RS++ G + + + + + SG +
Sbjct: 3121 RQGYHHEHSVDSSGHSGSHHSHTT--SQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHS 3178
Query: 109 QPLIEQEKCSDNYEAQAEKNQGQSEGNQHQ----SEGNPDKSEESQGQPEENHHSERSRN 164
+ + ++ QGQSEG++ S + D E + E SRN
Sbjct: 3179 VSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRN 3238
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQS---ERSHG--HSERSH-GHSERS 218
H QS RH ++ RSH + + HG S R G H+E S G + S
Sbjct: 3239 HRGSVQEQS--------RHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASS 3290
Query: 219 HGHSERSHGHSKRSRSQ 235
H + S G SR Q
Sbjct: 3291 HEQARSSPGERHGSRHQ 3307
Score = 45.1 bits (105), Expect = 8e-05
Identities = 60/236 (25%), Positives = 79/236 (33%), Gaps = 45/236 (19%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHR---------RGYSRCRSNSEEGNHDKKPSQKPSGFKS 101
RQ + + S H H RG S RS S ++++ S
Sbjct: 2797 RQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGS 2856
Query: 102 GQHPLNGQPLIEQEKCSDNYEAQAE-----KNQGQSEGNQHQSEGNPDKSEESQGQPEEN 156
H + I + S + Q+E + QG S SEG+ + SE G N
Sbjct: 2857 RHHEASTHADISRH--SQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRN 2914
Query: 157 HH----------SERSRNHLE---------RSLSQS------DRSQGQLKRHHPQYERSH 191
HH S R+H E S QS S GQ H Q S
Sbjct: 2915 HHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA 2974
Query: 192 GQYKRS-HGQSERSHGHSERSHGHSE---RSHGHSERSHGHSKRSRSQGDLVDTQS 243
G+ S H QS S HS HG + R GH S + + + DTQS
Sbjct: 2975 GERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS 3030
Score = 44.7 bits (104), Expect = 1e-04
Identities = 46/202 (22%), Positives = 72/202 (35%), Gaps = 12/202 (5%)
Query: 36 YKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQK 95
+KE + E + ++ + S Q H R S E+ + S +
Sbjct: 1423 HKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARN----SSR 1478
Query: 96 PSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEE 155
S + GQ + G P + +Y Q+ G S G H +S+ S GQ
Sbjct: 1479 HSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHS-GYHHSHTTPQGRSDASHGQSGP 1537
Query: 156 NHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHS 215
S ++RN + D S+ RHH R+ GQ E + + R G S
Sbjct: 1538 RSASRQTRNEEQ----SGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSS 1593
Query: 216 ERSHGHSERSHGHSKRSRSQGD 237
SE GHS+ S + +
Sbjct: 1594 VSQDRDSE---GHSEDSERRSE 1612
Score = 43.9 bits (102), Expect = 2e-04
Identities = 58/228 (25%), Positives = 87/228 (38%), Gaps = 51/228 (22%)
Query: 63 QQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF----------------KSGQHP- 105
Q S A R RG S +++ EG+ + +Q SG +SG+
Sbjct: 404 QASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSG 463
Query: 106 LNGQPL--IEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ-GQPEENHHSERS 162
+G L + + D+ + + G +G+ H+ + + SQ GQ H S
Sbjct: 464 RSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSS 523
Query: 163 R-----NHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQS-----------ERSHG 206
R +H E+S+++S S H + S G+ SHGQS E G
Sbjct: 524 RGGRQGSHHEQSVNRSGHSGS-----HHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSG 578
Query: 207 HSERSHG--HSER-----SHGHSERSHGHS---KRSRSQGDLVDTQSD 244
R G H E S HS+ G S + SR+QG V SD
Sbjct: 579 DGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD 626
Score = 43.9 bits (102), Expect = 2e-04
Identities = 54/224 (24%), Positives = 78/224 (34%), Gaps = 41/224 (18%)
Query: 62 RQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF-------KSGQHPLNGQP---- 110
RQ S A R RG S + + EG+ + +Q S +S + GQ
Sbjct: 1376 RQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESS 1435
Query: 111 --------LIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ-GQPEENHHSER 161
+ + S++ Q + G +G++H+ N + SQ GQ H
Sbjct: 1436 GRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGS 1495
Query: 162 SRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQS-----------ERSHGHSER 210
SR + S + + +H + G+ SHGQS E G R
Sbjct: 1496 SRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSR 1555
Query: 211 SHG--HSE-----RSHGHSERSHGH---SKRSRSQGDLVDTQSD 244
G H E S HS+ G SK SR QG V D
Sbjct: 1556 HSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRD 1599
Score = 43.5 bits (101), Expect = 2e-04
Identities = 44/191 (23%), Positives = 66/191 (34%), Gaps = 23/191 (12%)
Query: 59 SPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCS 118
S Q AH R S E+ + S + S + GQ + G P +
Sbjct: 3715 STHEQSESAHGRAGPSTGGRQGSRHEQA----RDSSRHSASQEGQDTIRGHPGSRRGGRQ 3770
Query: 119 DNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQG 178
+Y Q+ G S G+ H + +S+ S GQ S +RN + D S+
Sbjct: 3771 GSYHEQSVDRSGHS-GSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQ----SGDGSRH 3825
Query: 179 QLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHS--------------ERSHGHSER 224
RHH ++ GQ E + R G S ER + R
Sbjct: 3826 SGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASR 3885
Query: 225 SHGHSKRSRSQ 235
+H S R +S+
Sbjct: 3886 NHHGSSREQSR 3896
Score = 43.1 bits (100), Expect = 3e-04
Identities = 50/229 (21%), Positives = 85/229 (37%), Gaps = 47/229 (20%)
Query: 60 PSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF-KSGQHPLNGQPL------- 111
P Q S A R G S +++ EG+ ++ +Q SG ++G H + Q
Sbjct: 3319 PRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGG 3378
Query: 112 -----------IEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ-GQPEENHHS 159
+ + S++ + + G+ +G+ H+ + + SQ GQ H
Sbjct: 3379 RSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHP 3438
Query: 160 ERSR-----NHLERSLSQS----------------DRSQGQLKRHHPQYERSHGQYKRSH 198
SR +H E+S+ +S D S+GQ + + +
Sbjct: 3439 GSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDG 3498
Query: 199 GQSERSHGHSERSHGHSERSHGHSERSHGHS---KRSRSQGDLVDTQSD 244
+ SH H + S R HS+ G S + SR+QG V SD
Sbjct: 3499 SRHSWSHHHEASTQADSSR---HSQSGQGQSAGPRTSRNQGSSVSQDSD 3544
Score = 42.7 bits (99), Expect = 4e-04
Identities = 44/190 (23%), Positives = 66/190 (34%), Gaps = 43/190 (22%)
Query: 54 HSKKESPSRQQSKAHRHRHRRGYSRCRSNSEE--------GNHDKKPSQKPSGFKSGQHP 105
H +P + +H R SR N E+ G+ +PS + S +H
Sbjct: 1518 HHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAG---SSRHS 1574
Query: 106 LNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNH 165
GQ ++ ++ + QG S SEG+ + SE NH+
Sbjct: 1575 QVGQ--------GESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYG------ 1620
Query: 166 LERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERS 225
S R Q + +P RSH + SHGHS S S H + S
Sbjct: 1621 -------SAREQSRHGSRNP----------RSHQEDRASHGHSAESSRQSGTRHAETS-S 1662
Query: 226 HGHSKRSRSQ 235
G + S+ Q
Sbjct: 1663 GGQAASSQEQ 1672
Score = 42.7 bits (99), Expect = 4e-04
Identities = 58/225 (25%), Positives = 81/225 (36%), Gaps = 52/225 (23%)
Query: 63 QQSKAHRHRHRRGYSRCRSNSEEGNHDK--KPSQKPSGFKSGQHPLNGQPLIEQEKCSDN 120
Q S + G + + +G+H K + S + S + GQ ++G P +
Sbjct: 2417 QVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGS 2476
Query: 121 YEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENH-HS-ERSRNHLERSLSQS-DRSQ 177
+ Q G S G+ SQG+ + +H HS RS + R+ QS D S+
Sbjct: 2477 HYEQLVDRSGHS--------GSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSR 2528
Query: 178 GQLKRHHPQYER--SHGQYKRSHGQSE----------------RSHGHSERS-------- 211
RHH R S G + GQSE S GHSE S
Sbjct: 2529 HSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSAS 2588
Query: 212 ---HGHSE----------RSHGHSERSHGHSKRSRSQGDLVDTQS 243
HG ++ RSH HGHS S Q TQ+
Sbjct: 2589 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQT 2633
Score = 42.4 bits (98), Expect = 5e-04
Identities = 53/227 (23%), Positives = 81/227 (35%), Gaps = 49/227 (21%)
Query: 63 QQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF-KSGQHPLNGQPL---------- 111
Q S A R RG S ++ EG+ + +Q SG ++G H + Q
Sbjct: 729 QASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSR 788
Query: 112 --------IEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ-------GQP--- 153
+ K S++ + G +G+ H+ + + SQ G P
Sbjct: 789 RSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSS 848
Query: 154 ----EENHHSE------RSRNHLERSLSQ--SDRSQGQLKRHHPQYERSHGQYKRSHGQS 201
+ +HH + S +H + SQ SD S+GQ + + R +
Sbjct: 849 RRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRH 908
Query: 202 ERSHGHSERSHG----HSERSHGHSERSHGHSKRSRSQGDLVDTQSD 244
S H SH HS+ G SE S+ SR QG V SD
Sbjct: 909 SGSRHHEASSHADISRHSQAGQGQSE----GSRTSRRQGSSVSQDSD 951
Score = 42.4 bits (98), Expect = 5e-04
Identities = 54/226 (23%), Positives = 87/226 (38%), Gaps = 37/226 (16%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEE--GNHDKKPSQKPS 97
+G++ ++ + Q HS E R A R+ + + R S +H+ + S
Sbjct: 1914 QGSSVSQDSDS-QGHS--EDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHS 1970
Query: 98 GFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEES---QGQPE 154
S Q + + + ++E QA + G+ G+ HQ + + D S S GQ
Sbjct: 1971 ADSSRQSGTRHTESSSRGQAASSHE-QARSSAGERHGSHHQLQ-SADSSRHSGIGHGQAS 2028
Query: 155 E-----------NHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERS-HGQYKRS----- 197
+ S H E S +QS +QG+ H ++ S GQ S
Sbjct: 2029 SAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSG 2088
Query: 198 --------HGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQ 235
H QSE +HG S S G R H +++ S+ S SQ
Sbjct: 2089 SFLYQVSTHEQSESTHGQSAPSTG--GRQGSHYDQAQDSSRHSASQ 2132
Score = 42.4 bits (98), Expect = 5e-04
Identities = 49/217 (22%), Positives = 82/217 (37%), Gaps = 31/217 (14%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRG-------YSRCRSNSEEGNHDKKP 92
+G++ E+ ++ ++ + +E + + H RRG S RS +H
Sbjct: 3411 QGSHHEQARDSSRHSASQEG--QDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTT 3468
Query: 93 SQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQ 152
SQ S GQ +G ++ +D ++ S + H++ D S SQ
Sbjct: 3469 SQGRSDASRGQ---SGSRSASRQTRNDEQSGDGSRH---SWSHHHEASTQADSSRHSQSG 3522
Query: 153 PEENHHSERSRNHLERSLSQ----------SDRSQGQLKRHH----PQYERSHGQYKRSH 198
++ SRN S+SQ S+R G R+H + R ++ SH
Sbjct: 3523 QGQSAGPRTSRNQ-GSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSH 3581
Query: 199 GQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQ 235
+ HGHS S S H + S G + S Q
Sbjct: 3582 HEDRAGHGHSAESSRQSGTHHAENS-SGGQAASSHEQ 3617
Score = 41.2 bits (95), Expect = 0.001
Identities = 43/193 (22%), Positives = 65/193 (33%), Gaps = 18/193 (9%)
Query: 63 QQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF-KSGQHPLNGQPLIEQEKCSDN- 120
Q S A R RGYS +++ EG+ + +Q S K+G H + + + +
Sbjct: 2026 QASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSG 2085
Query: 121 ------YEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSD 174
Y+ + + G S G S Q Q H + + R
Sbjct: 2086 RSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPS 2145
Query: 175 RSQGQLKRHHPQYERS-----HGQYKRSHGQSERSHGHS-----ERSHGHSERSHGHSER 224
R Q +RS H + S G+S+ S G S R E+S S
Sbjct: 2146 RGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRH 2205
Query: 225 SHGHSKRSRSQGD 237
S H + S D
Sbjct: 2206 SGSHHHEASSWAD 2218
Score = 40.8 bits (94), Expect = 0.002
Identities = 53/220 (24%), Positives = 85/220 (38%), Gaps = 31/220 (14%)
Query: 41 GTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFK 100
GT E + Q S +E + H RH++ S+++ G ++ S
Sbjct: 1654 GTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSAD---SSTDSGTGRRQDSSVVGD-- 1708
Query: 101 SGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSE 160
SG +G + E S+ + Q+ GQ+ +Q + E ++GQ E S
Sbjct: 1709 SGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQ------ESTRGQSGE--RSG 1760
Query: 161 RSRNHL------ERSLSQSDR---SQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERS 211
RS + L E+S S R S G +R + R ++ S + GH S
Sbjct: 1761 RSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSS 1820
Query: 212 HGHSERSH--------GHSERSHGHSKRSRSQGDLVDTQS 243
G + SH GHS H H+ S+ + D+ QS
Sbjct: 1821 RGGRQGSHYEQSVDSSGHSGSHHSHT-TSQERSDVSRGQS 1859
Score = 39.7 bits (91), Expect = 0.003
Identities = 51/206 (24%), Positives = 76/206 (36%), Gaps = 45/206 (21%)
Query: 51 RQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQP 110
R + S +S SR S+ R+ + G S S H + +Q S +H +GQ
Sbjct: 3796 RSDASHGQSGSRSASRETRNEEQSGDGSRHSGSR---HHEASTQADSS----RHSQSGQ- 3847
Query: 111 LIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSL 170
++ ++ + QG S SE P+ SE NHH
Sbjct: 3848 -------GESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHG----------- 3889
Query: 171 SQSDRSQGQLKRHHPQYER----SHGQYK--RSHGQSERSHGH----SERSHGHS---ER 217
S R Q + HP SH Q +S + + HGH S+ S HS R
Sbjct: 3890 --SSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSR 3947
Query: 218 SHGHSERSHGH----SKRSRSQGDLV 239
HS S+ + ++R + Q LV
Sbjct: 3948 GSPHSSSSYHYQSEGTERQKGQSGLV 3973
Score = 38.5 bits (88), Expect = 0.008
Identities = 43/186 (23%), Positives = 75/186 (40%), Gaps = 19/186 (10%)
Query: 57 KESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKK--PSQKPSGFKSGQHPLNGQPLIEQ 114
+ PS + RH R SR S S+EG + P + G + H + +++
Sbjct: 3726 RAGPSTGGRQGSRHEQARDSSR-HSASQEGQDTIRGHPGSRRGGRQGSYH----EQSVDR 3780
Query: 115 EKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSD 174
S ++ + +QG+S+ + QS G+ S E++ + + S S + + +Q+D
Sbjct: 3781 SGHSGSHHSHTT-SQGRSDASHGQS-GSRSASRETRNEEQSGDGSRHSGSRHHEASTQAD 3838
Query: 175 RSQ----GQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSK 230
S+ GQ + + R G SE SER + R+H HG S+
Sbjct: 3839 SSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNH------HGSSR 3892
Query: 231 RSRSQG 236
G
Sbjct: 3893 EQSRDG 3898
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 57.4 bits (137), Expect = 2e-08
Identities = 58/291 (19%), Positives = 118/291 (40%), Gaps = 14/291 (4%)
Query: 28 MSLDDIIIYKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEE-- 85
M + +++++ E EEK Q +++ RQ+ + R + +R + +E
Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 485
Query: 86 --GNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYE--AQAEKNQGQSE-----GNQ 136
+K Q+ ++ + + + E+EK + E Q EK + Q E
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI 545
Query: 137 HQSEGNPDKSEESQGQPEENHH--SERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQY 194
H+ E K EE + EE H E+ R E+ Q ++ + Q ++ Q E+ Q
Sbjct: 546 HEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQE 605
Query: 195 KRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLIA 254
+ + Q E+ E+ E+ E+ ++ R Q + Q + I Q +++
Sbjct: 606 EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 665
Query: 255 TQKDLIATQRDLIATQRDLIVTQRD-LVATERDLINQSGRSHGQSERHQRY 304
Q++ + Q + + Q + + Q + + E + Q R Q E+ Q +
Sbjct: 666 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 716
Score = 32.7 bits (73), Expect = 0.43
Identities = 38/192 (19%), Positives = 75/192 (39%), Gaps = 6/192 (3%)
Query: 113 EQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEE-NHHSERSRNHLERSLS 171
E + S +AQ E+N+ + NQ Q E + E+ Q E+ E+ R E+
Sbjct: 334 ELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIRE 393
Query: 172 QSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSK- 230
Q ++ + Q + + E+ Q + + E+ E E+ E+ H K
Sbjct: 394 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKI 453
Query: 231 ---RSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDL 287
+ Q + + + Q + Q++ I Q + I Q + + Q + + E++
Sbjct: 454 REQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKI-HEQEK 512
Query: 288 INQSGRSHGQSE 299
I + + Q E
Sbjct: 513 IREEEKRQEQEE 524
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 56.2 bits (134), Expect = 4e-08
Identities = 57/221 (25%), Positives = 87/221 (39%), Gaps = 22/221 (9%)
Query: 31 DDIIIYKELEGTNAEEEKNKRQNHSKKESP---------SRQQSKAHRHRHRRGYSRCRS 81
DD I+ +++ T+ + +KNK ++ +KE R +S H+ R R SR R+
Sbjct: 1788 DDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRA 1847
Query: 82 NSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEG 141
SQ S +S + + + + K EK + +H+S+
Sbjct: 1848 RKRSSKSKSHRSQTRSRSRSRRRRRSSR---SRSKSRGRRSVSKEKRK---RSPKHRSKS 1901
Query: 142 NPDKSEESQGQPEENHHSERSRNHLERSLSQS------DRSQGQLKRHH-PQYERSHGQY 194
K + S + RSR RS S + RS G+ + RS
Sbjct: 1902 RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPS 1961
Query: 195 KRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQ 235
+RS S RS S RS S RS S RS S+R RS+
Sbjct: 1962 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002
Score = 37.4 bits (85), Expect = 0.017
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 6/167 (3%)
Query: 44 AEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQ 103
+E R+ SK +S Q R R RR SR RS S K +K +S +
Sbjct: 1841 SESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRK----RSPK 1896
Query: 104 HPLNGQPLIEQEKCS-DNYEAQAEKNQGQSEGNQHQSEGNPDKSEE-SQGQPEENHHSER 161
H + + S DN + +++ S ++ + +S + + S R
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRR 1956
Query: 162 SRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHS 208
SR RS + S RS+ +R RS +RS S R S
Sbjct: 1957 SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Score = 30.8 bits (68), Expect = 1.6
Identities = 39/204 (19%), Positives = 68/204 (33%), Gaps = 18/204 (8%)
Query: 110 PLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPD-----KSEESQGQPEENHHSERSRN 164
PL+ + D A + ++ SE D K +++ + ++N + R +
Sbjct: 1755 PLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKN--RDKG 1812
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSER 224
E+ S RS+ + + R RS + S S RS S R
Sbjct: 1813 EKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRR 1872
Query: 225 SHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATE 284
S +SR + + + R +K ++ RD R V
Sbjct: 1873 SSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD-----------NRKTVRAR 1921
Query: 285 RDLINQSGRSHGQSERHQRYSTGK 308
++ RSH S R + S G+
Sbjct: 1922 SRTPSRRSRSHTPSRRRRSRSVGR 1945
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 56.2 bits (134), Expect = 4e-08
Identities = 57/221 (25%), Positives = 87/221 (39%), Gaps = 22/221 (9%)
Query: 31 DDIIIYKELEGTNAEEEKNKRQNHSKKESP---------SRQQSKAHRHRHRRGYSRCRS 81
DD I+ +++ T+ + +KNK ++ +KE R +S H+ R R SR R+
Sbjct: 1788 DDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRA 1847
Query: 82 NSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEG 141
SQ S +S + + + + K EK + +H+S+
Sbjct: 1848 RKRSSKSKSHRSQTRSRSRSRRRRRSSR---SRSKSRGRRSVSKEKRK---RSPKHRSKS 1901
Query: 142 NPDKSEESQGQPEENHHSERSRNHLERSLSQS------DRSQGQLKRHH-PQYERSHGQY 194
K + S + RSR RS S + RS G+ + RS
Sbjct: 1902 RERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPS 1961
Query: 195 KRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQ 235
+RS S RS S RS S RS S RS S+R RS+
Sbjct: 1962 RRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSR 2002
Score = 37.4 bits (85), Expect = 0.017
Identities = 41/167 (24%), Positives = 63/167 (37%), Gaps = 6/167 (3%)
Query: 44 AEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQ 103
+E R+ SK +S Q R R RR SR RS S K +K +S +
Sbjct: 1841 SESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRK----RSPK 1896
Query: 104 HPLNGQPLIEQEKCS-DNYEAQAEKNQGQSEGNQHQSEGNPDKSEE-SQGQPEENHHSER 161
H + + S DN + +++ S ++ + +S + + S R
Sbjct: 1897 HRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRR 1956
Query: 162 SRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHS 208
SR RS + S RS+ +R RS +RS S R S
Sbjct: 1957 SRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRS 2003
Score = 30.8 bits (68), Expect = 1.6
Identities = 39/204 (19%), Positives = 68/204 (33%), Gaps = 18/204 (8%)
Query: 110 PLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPD-----KSEESQGQPEENHHSERSRN 164
PL+ + D A + ++ SE D K +++ + ++N + R +
Sbjct: 1755 PLLASDVGRDRSAASPVVSSMPERASESSSEEKDDYEIFVKVKDTHEKSKKNKN--RDKG 1812
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSER 224
E+ S RS+ + + R RS + S S RS S R
Sbjct: 1813 EKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRR 1872
Query: 225 SHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATE 284
S +SR + + + R +K ++ RD R V
Sbjct: 1873 SSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRD-----------NRKTVRAR 1921
Query: 285 RDLINQSGRSHGQSERHQRYSTGK 308
++ RSH S R + S G+
Sbjct: 1922 SRTPSRRSRSHTPSRRRRSRSVGR 1945
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 55.5 bits (132), Expect = 6e-08
Identities = 41/207 (19%), Positives = 84/207 (40%), Gaps = 6/207 (2%)
Query: 45 EEEK---NKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEE-GNHDKKPSQKPSGFK 100
+EEK K+ +K++ +++ R R + R E ++K ++ +
Sbjct: 532 QEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Query: 101 SGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEEN--HH 158
+ + Q QE+ +E + + + + E + E + EE + EE
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Query: 159 SERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERS 218
E+ R E+ Q ++ QGQ ++ Q E+ GQ ++ Q E+ G E+ G E+
Sbjct: 652 EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM 711
Query: 219 HGHSERSHGHSKRSRSQGDLVDTQSDL 245
G E+ G + + + D + +
Sbjct: 712 WGQEEKMWGQEEMREKEERIRDQKEKM 738
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 55.1 bits (131), Expect = 8e-08
Identities = 44/199 (22%), Positives = 82/199 (41%), Gaps = 12/199 (6%)
Query: 49 NKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNG 108
NK ++ S+ SP + + ++ + RS S D+ S+ PS K H G
Sbjct: 432 NKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS--KERDHSQLG 489
Query: 109 QPLIEQE---KCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNH 165
P E++ S + E Q +++ S+ H+ +P K + + N +RS++
Sbjct: 490 SPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSR 549
Query: 166 L---ERSLSQS---DRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHS-ERSHGHSERS 218
ER QS + + + + P ER Q + S + + S S + G+S
Sbjct: 550 SPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPR 609
Query: 219 HGHSERSHGHSKRSRSQGD 237
E++H S+ +G+
Sbjct: 610 ASSKEKAHSRSRTPSKEGN 628
Score = 53.9 bits (128), Expect = 2e-07
Identities = 54/223 (24%), Positives = 86/223 (38%), Gaps = 37/223 (16%)
Query: 18 PSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYS 77
PSR+K S + ++ N +++ Q+HS+ SP R +S + + H S
Sbjct: 251 PSREK------SYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTH----S 300
Query: 78 RCRSNSEEGNHDKKPSQKPSGFKS--GQHPLNGQPLIEQEKCSDNYEAQAEKNQGQS--- 132
R RS+S + NH + S+ G S G+H S + K+Q QS
Sbjct: 301 RVRSHSWKRNHSRARSRTRKGILSQMGRH-------------SQSRSHSKGKSQNQSRTP 347
Query: 133 -EGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSH 191
G H NP K + +H S+ R S + G+ + P +R H
Sbjct: 348 RRGRSHNWSRNPSK------ERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDH 401
Query: 192 GQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRS 234
+ + + +RS S + +RS S RSRS
Sbjct: 402 SRSRSPNKARDRSRSRS--PYKARDRSRSRSPNKARDCSRSRS 442
Score = 51.2 bits (121), Expect = 1e-06
Identities = 51/209 (24%), Positives = 83/209 (39%), Gaps = 19/209 (9%)
Query: 41 GTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGY-SRCRSNSEEGNHDKKPSQKPSGF 99
G + NK+++HS+ SP++ + R R R Y +R RS S N + S+ S +
Sbjct: 388 GRSQSGSPNKQRDHSRSRSPNKARD---RSRSRSPYKARDRSRSRSPNKARDCSRSRSPY 444
Query: 100 KSGQHPLNGQPLIEQEKC---SDNYEAQAEKNQGQSEGNQHQSEGNPDK--------SEE 148
K+ + P ++ S N +++ S+ H G+P K S
Sbjct: 445 KARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
Query: 149 SQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHS 208
+ Q ++ S + R+H RS S S Q + R P ER Q + ER H S
Sbjct: 505 KERQCRQSRSSSKERDH-RRSRSPSKERQRRQSR-SPNKERDRSQSRSP--SEEREHRQS 560
Query: 209 ERSHGHSERSHGHSERSHGHSKRSRSQGD 237
+R S ++SRS +
Sbjct: 561 RSPSKERDRRRWRSPSKERERRQSRSSSE 589
Score = 40.8 bits (94), Expect = 0.002
Identities = 57/226 (25%), Positives = 87/226 (38%), Gaps = 48/226 (21%)
Query: 55 SKKESPSRQQ--SKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQ--------- 103
S+ +P+ QQ S+ + R +R RS+S+ N KK + P G G+
Sbjct: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPS 215
Query: 104 ----HPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHS 159
G P E+ ++ K+ GQ + +P +E S N S
Sbjct: 216 TAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSP--TEMSSRVKSYNQAS 273
Query: 160 ERSR--NHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSH---------------GQSE 202
RSR +H + + RS G KR H + RSH +KR+H G+
Sbjct: 274 TRSRPQSHSQSRSPRRSRS-GSQKRTHSRV-RSHS-WKRNHSRARSRTRKGILSQMGRHS 330
Query: 203 RSHGHSE-----------RSHGHSERSHGHSERSHGHSKRSRSQGD 237
+S HS+ R H+ + ERSH HS+ S + D
Sbjct: 331 QSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERD 376
Score = 39.7 bits (91), Expect = 0.003
Identities = 30/151 (19%), Positives = 62/151 (41%), Gaps = 6/151 (3%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
+ ++ +E++ R++ S + R+QS++ R SR S E + PS K
Sbjct: 511 QSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPS-KERDR 569
Query: 100 KSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHS 159
+ + P + + S+ + ++ + G + +K+ P + +
Sbjct: 570 RRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNH 629
Query: 160 ERSRNHLERSLSQSDRSQGQLKRHHPQYERS 190
+SR S +SD SQ + R P ++RS
Sbjct: 630 SQSRT----SSKESDPSQSTVPR-SPDWKRS 655
Score = 30.0 bits (66), Expect = 2.8
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 5/84 (5%)
Query: 42 TNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKS 101
T ++E + + S KES Q + +R +R S S+ K S PS F S
Sbjct: 622 TPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPS 681
Query: 102 GQHPLNGQPLIEQEKCSDNYEAQA 125
G GQ L + + +D ++A
Sbjct: 682 G-----GQTLSQDDSQADATTSKA 700
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 55.1 bits (131), Expect = 8e-08
Identities = 60/259 (23%), Positives = 106/259 (40%), Gaps = 28/259 (10%)
Query: 40 EGTNAEEEKNKR----QNHSKKESPSRQQSKAHRHRHR---RGYSRCRSNSEEGNHDKKP 92
E N + EK K+ +++SK+ R K +++++ R S+ RS S+E + K+
Sbjct: 414 ESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKER 473
Query: 93 SQKPSG-----FKSGQHPLNGQPLIEQEKCSDNYEAQAEKN-------QGQSEGNQHQSE 140
K + +S + + + E+EK SD+ E++ Q +S+ N+H
Sbjct: 474 DSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHS 533
Query: 141 GNPDKSEESQGQPEE-----NHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYK 195
+ +K +Q + E HS SR ERS S+ DRS+ R H + +Y
Sbjct: 534 KSKEKDRRAQSRSRECDITKGKHSYNSRTR-ERSRSR-DRSRRVRSRTHDRDRSRSKEYH 591
Query: 196 RSHGQSERSHGHSERSHGHSE--RSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLI 253
R Q R G S + RS R RS + + D Q
Sbjct: 592 RYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKS 651
Query: 254 ATQKDLIATQRDLIATQRD 272
+ +K+ +++ + + RD
Sbjct: 652 SHRKENSESEKRMYSKSRD 670
Score = 54.7 bits (130), Expect = 1e-07
Identities = 44/208 (21%), Positives = 90/208 (43%), Gaps = 20/208 (9%)
Query: 46 EEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSR---CRSNSEEGNHDKKPSQKPSGFKSG 102
+E+ + + ESP+R+ K + + + S+ R NSE+ + K +K + KS
Sbjct: 402 KERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRA--KSK 459
Query: 103 QHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERS 162
+ + +E+ S + + ++ + +S+G H++ +K +S+G+ +E S+
Sbjct: 460 SRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEK 519
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQ--------------YERSHGQYKRSHGQSERSHGHS 208
LE ++ D S+ + K Q Y + RS +S R +
Sbjct: 520 SKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRT 579
Query: 209 -ERSHGHSERSHGHSERSHGHSKRSRSQ 235
+R S+ H + E+ + RSRS+
Sbjct: 580 HDRDRSRSKEYHRYREQEYRRRGRSRSR 607
Score = 33.9 bits (76), Expect = 0.19
Identities = 30/161 (18%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 42 TNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDK---KPSQKPSG 98
+++ + + S ES + ++SK + +HR+ NS + +K K S+K +
Sbjct: 204 SDSSSDSQSSSDSSDSESATEEKSKKRKKKHRK-------NSRKHKKEKKKRKKSKKSAS 256
Query: 99 FKSGQHPLNGQP--LIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEEN 156
+S L QP + E+ E + + + ++ + + N ++ E + P +
Sbjct: 257 SESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERK-NRERERERECNPPNS 315
Query: 157 HHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRS 197
+ R L + + +G + P RS +++RS
Sbjct: 316 QPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRS 356
Score = 33.5 bits (75), Expect = 0.25
Identities = 41/212 (19%), Positives = 81/212 (38%), Gaps = 29/212 (13%)
Query: 46 EEKNKRQNHSK-KESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
E K+ +HSK KE R QS++ +G S + E + + S++ +S H
Sbjct: 524 ESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRR---VRSRTH 580
Query: 105 PLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKS---------------EES 149
+ E + Y Q + +G+S + ++ +S EES
Sbjct: 581 DRDRSRSKEYHR----YREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREES 636
Query: 150 QGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQS-----ERS 204
Q + ++ + ++ S++ + S+S++ R H S + K QS ++S
Sbjct: 637 QSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSR-EKKADRDQSPFSKIKQS 695
Query: 205 HGHSERSHGHSERSHGHSERSHGHSKRSRSQG 236
+E + RS + +S+G
Sbjct: 696 SQDNELKSSMLKNKEDEKIRSSVEKENQKSKG 727
Score = 33.5 bits (75), Expect = 0.25
Identities = 26/126 (20%), Positives = 51/126 (40%), Gaps = 6/126 (4%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRS-NSEEGNHDKKPSQK 95
++ + EE +++ ++ + + K + +R YS+ R NS + +KK +
Sbjct: 626 RDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRD 685
Query: 96 PSGFKSGQHPLNGQPL---IEQEKCSDNYEAQAEKNQGQSEG--NQHQSEGNPDKSEESQ 150
S F + L + + K + + EK +S+G N H E N ES
Sbjct: 686 QSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESS 745
Query: 151 GQPEEN 156
+E+
Sbjct: 746 PGTDED 751
Score = 32.3 bits (72), Expect = 0.56
Identities = 49/239 (20%), Positives = 93/239 (38%), Gaps = 46/239 (19%)
Query: 38 ELEGTNAEEEKNKRQNHSKKESPSRQQ----SKAHRHRHRRGYSRCRSNSEEGNHDK-KP 92
E E N E E+ + N + S Q+ +++ R RG R R+ S + D+ +
Sbjct: 296 EKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRR 355
Query: 93 SQKPSGFK------------SGQHPLNGQPL--------------IEQEKCSDN---YEA 123
S+ P ++ SG+ + G +++ K +D+ E+
Sbjct: 356 SETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSES 415
Query: 124 QAEKNQGQSEGNQHQSEG-------NPDKSEESQGQPEENHHSERSRNHLERSLSQ---S 173
KN+ + + H+S N +K ++ + + ++ S+ E+S S+ S
Sbjct: 416 PNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDS 475
Query: 174 DRSQGQLKRHHPQYE-RSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSE-RSHGHSK 230
++ + KR + + R H K QS+ ERS + S+ H HSK
Sbjct: 476 KHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSK 534
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 53.9 bits (128), Expect = 2e-07
Identities = 47/194 (24%), Positives = 73/194 (37%), Gaps = 12/194 (6%)
Query: 54 HSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLN------ 107
H + +R H + G SR G+ + S+ SGF H
Sbjct: 1771 HGQTGDTTRHAHSGHGQSTQTG-SRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQA 1829
Query: 108 GQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRN--H 165
G E E D G + G+ G +S S + HSE S + H
Sbjct: 1830 GSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESSDSEVH 1889
Query: 166 LERSLSQSDRSQGQLKRHHPQYERS-HGQYKRSHGQSERSHGHSERSHGHSER--SHGHS 222
S + S + Q + H + E + H +++ +HGQ+ + H SHG + + S
Sbjct: 1890 SGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTG 1949
Query: 223 ERSHGHSKRSRSQG 236
R GHS+ S S+G
Sbjct: 1950 RRGSGHSEYSDSEG 1963
Score = 46.6 bits (109), Expect = 3e-05
Identities = 45/210 (21%), Positives = 75/210 (35%), Gaps = 20/210 (9%)
Query: 36 YKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGN-----HDK 90
Y + T R+ ES + H H G++ +S S+ G HD+
Sbjct: 1481 YHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHS-GHTHGQSGSQHGESESIIHDR 1539
Query: 91 KPSQKPSGFKSGQHPLNGQPLIEQ--------EKCSDNYEAQAEKNQGQSEGNQHQSEGN 142
+ +H +G Q ++ S + +E + G S H E
Sbjct: 1540 HRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSH-RPHSREHT 1598
Query: 143 PDKSEESQGQPEENHHSERSRNH--LERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQ 200
++ +PE H H + + S GQ + R+ G+ + SH +
Sbjct: 1599 YGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRG---SRTTGRQRSSHSE 1655
Query: 201 SERSHGHSERSHGHSERSHGHSERSHGHSK 230
S S HS SH H+ +HG + HG S+
Sbjct: 1656 SSDSEVHSGVSHTHTGHTHGQAGSQHGQSE 1685
Score = 44.7 bits (104), Expect = 1e-04
Identities = 53/232 (22%), Positives = 83/232 (35%), Gaps = 38/232 (16%)
Query: 36 YKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHR-HRHRRGYSRCRSNSEE--------- 85
+++ T + +R +HS+ +HR H Y + S EE
Sbjct: 1558 HEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERH 1617
Query: 86 ----GNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSE-------- 133
G SG GQ G +++ S + + +E + G S
Sbjct: 1618 GTTHGQIGDTTGHSHSGH--GQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHG 1675
Query: 134 --GNQH-QSEGN-PDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYER 189
G+QH QSE P++ + GQ + + + H + R+ G+
Sbjct: 1676 QAGSQHGQSESIVPERHGTTHGQTGDT--TRHAHYHHGLTTQTGSRTTGRRGS------- 1726
Query: 190 SHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVDT 241
H +Y S G S SH HS +HG + HG SE S H + G DT
Sbjct: 1727 GHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESE-SIVHERHGTIHGQTGDT 1777
Score = 44.3 bits (103), Expect = 1e-04
Identities = 41/187 (21%), Positives = 66/187 (35%), Gaps = 12/187 (6%)
Query: 67 AHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAE 126
AH H + R+ G+ + S G+ H +G + E+
Sbjct: 1706 AHYHHGLTTQTGSRTTGRRGSGHSEYSDS-EGYSGVSHTHSGHTHGQARSQHGESESIVH 1764
Query: 127 KNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQ 186
+ G G + + Q RS H E S S+ G +R H +
Sbjct: 1765 ERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSE--YSDSEGHSGFSQRPHSR 1822
Query: 187 YERSHGQYKRSHGQSER--------SHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDL 238
+HGQ HG+SE +HG + + GHS+ HG S +S + R G
Sbjct: 1823 -GHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHS 1881
Query: 239 VDTQSDL 245
+ S++
Sbjct: 1882 ESSDSEV 1888
Score = 43.9 bits (102), Expect = 2e-04
Identities = 46/216 (21%), Positives = 77/216 (35%), Gaps = 36/216 (16%)
Query: 50 KRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDK---KPSQKPSGFKSGQ--- 103
+R HS+ +H H G++ ++ S+ G + K Q G ++G
Sbjct: 1876 RRSGHSESSDSEVHSGGSHTHS---GHTHSQARSQHGESESTVHKRHQTTHG-QTGDTTE 1931
Query: 104 --HPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEE---NHH 158
HP +GQ + + + +G SEG S G +H+
Sbjct: 1932 HGHPSHGQTIQTGSRTTGR--------RGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHY 1983
Query: 159 SERSRNHLERSLSQSDRSQGQLKRHHPQY-------ERSHGQYKRSHGQSERSHGHSERS 211
E + ER + ++ + H + R+ G+ H + S GHS S
Sbjct: 1984 PESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVS 2043
Query: 212 HGHSERSHGHSERSHG------HSKRSRSQGDLVDT 241
H HS +HG + HG H + + G DT
Sbjct: 2044 HTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDT 2079
Score = 42.7 bits (99), Expect = 4e-04
Identities = 41/193 (21%), Positives = 61/193 (31%), Gaps = 24/193 (12%)
Query: 49 NKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNG 108
++ Q HS+ S + RH Y + + G+ SG GQ G
Sbjct: 1365 SQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGH---------SGH--GQSTQRG 1413
Query: 109 QPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLER 168
+ + + +E + G S P E++ GQ H S H
Sbjct: 1414 SRTTGRRGSGHSESSDSEVHSGGSH--------RPQSQEQTHGQAGSQHGESGSTVHGRH 1465
Query: 169 SLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHG--HSERSHGHSERSH 226
+ H Y + S R GHSE S HS SH HS +H
Sbjct: 1466 GTTHGQTGD---TTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTH 1522
Query: 227 GHSKRSRSQGDLV 239
G S + + +
Sbjct: 1523 GQSGSQHGESESI 1535
Score = 42.0 bits (97), Expect = 7e-04
Identities = 58/202 (28%), Positives = 77/202 (38%), Gaps = 32/202 (15%)
Query: 59 SPSRQQSKAHRHRHRRGYSR-------CRSNSEEGNHDKKPSQKPSGFKSGQHPLN-GQP 110
S S Q S +H R G+S +S G H Q SGF GQH L+ GQ
Sbjct: 673 SGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQT-SGF--GQHELSSGQS 729
Query: 111 LIEQEKCSDNYEA----QAEKNQGQSEG-NQHQSE-GNPDKSEESQGQPEEN---HHSER 161
+ S + ++ Q GQS G QH+S G + S G + + H R
Sbjct: 730 SSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSR 789
Query: 162 SRNHLERSLSQSDRSQGQLKRHHPQY------ERSHGQYKRSHGQSERSHGHSERSHGHS 215
+ + S S +S G QY GQ+ GQS H RSH S
Sbjct: 790 QTSGFGQHGSGSSQSTG-----FGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSS 844
Query: 216 ERSHGH-SERSHGHSKRSRSQG 236
HG S +S G+ + S G
Sbjct: 845 YGQHGSGSSQSSGYGQHGSSSG 866
Score = 42.0 bits (97), Expect = 7e-04
Identities = 44/202 (21%), Positives = 74/202 (36%), Gaps = 23/202 (11%)
Query: 54 HSKKESPSRQQSKAHRHRHR-RGYS--------RCRSNSEEGNHDKKPSQKPSGFKSGQ- 103
H ++E+ Q RH +G S R R +S+ N D + K S S
Sbjct: 1233 HGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHI 1292
Query: 104 HPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSR 163
H G + + +G + + H G ++ + HS+ +
Sbjct: 1293 HTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATD 1352
Query: 164 NHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRS-HGQSERSHGHSERSHGHSERSHGHS 222
+ + +S SQ Q H Q HG+ + + H + E ++G + + GH HG S
Sbjct: 1353 SEVHSGVSHRPHSQEQT---HSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQS 1409
Query: 223 ---------ERSHGHSKRSRSQ 235
R GHS+ S S+
Sbjct: 1410 TQRGSRTTGRRGSGHSESSDSE 1431
Score = 41.6 bits (96), Expect = 0.001
Identities = 45/217 (20%), Positives = 76/217 (35%), Gaps = 29/217 (13%)
Query: 36 YKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRH-----RRGYSRCRSNSEEGNHDK 90
Y + EG + + H + S + RH + G + ++S G +
Sbjct: 1731 YSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQ 1790
Query: 91 KPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ 150
S + +G +S H + SD+ + S G+ H G+ + ES+
Sbjct: 1791 TGS-RTTGRRSSGH----------SEYSDSEGHSGFSQRPHSRGHTHGQAGS--QHGESE 1837
Query: 151 GQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSER 210
+E H + + SQS Q + G+ + H +S S HS
Sbjct: 1838 SIVDERHGTTHGQTGDTSGHSQSGHGQSTQSG-----SSTTGRRRSGHSESSDSEVHSGG 1892
Query: 211 SHGHSERSHGHSERSHG------HSKRSRSQGDLVDT 241
SH HS +H + HG H + + G DT
Sbjct: 1893 SHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDT 1929
Score = 41.2 bits (95), Expect = 0.001
Identities = 48/207 (23%), Positives = 73/207 (35%), Gaps = 38/207 (18%)
Query: 54 HSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIE 113
H ++ +R H + G SR + D S+ SG H
Sbjct: 1315 HGQRGDTTRHGHSGHGQSTQTG-SRTSGRQRFSHSDATDSEVHSGVSHRPHS-------- 1365
Query: 114 QEKCSDNYEAQAEKNQGQSEGNQHQS-EGNPDKSEESQGQPEENHHSER---SRNHLERS 169
+ +QA G+SE H+ E ++ E+ G H SR R
Sbjct: 1366 ----QEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRRG 1421
Query: 170 LSQSDRSQGQLKR---HHPQ-YERSHGQYKRSHGQSER--------SHGHSERSHGHSER 217
S+ S ++ H PQ E++HGQ HG+S +HG + + H+
Sbjct: 1422 SGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHY 1481
Query: 218 SHGHS---------ERSHGHSKRSRSQ 235
HG S R GHS+ S S+
Sbjct: 1482 HHGKSTQRGSSTTGRRGSGHSESSDSE 1508
Score = 41.2 bits (95), Expect = 0.001
Identities = 45/194 (23%), Positives = 72/194 (37%), Gaps = 16/194 (8%)
Query: 54 HSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIE 113
H + +R H +RG SR G+ + S+ SG H +G +
Sbjct: 2073 HGQTGDTTRHAHSGHGQSTQRG-SRTAGRRGSGHSESSDSEVHSGVS---HTHSGHTYGQ 2128
Query: 114 QEKCSDNYEAQAEKNQGQSEGN-----QHQSEGNPDKSE---ESQGQPEENH-HSERSRN 164
+ QG G +H G+ ++ + G+ +H S S
Sbjct: 2129 ARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEV 2188
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERS-HGQYKRSHGQSERSHGHSERSHGHSER--SHGH 221
H E S + S + Q H Q S HG+ +HGQ+ + H+ +G S + S
Sbjct: 2189 HSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTT 2248
Query: 222 SERSHGHSKRSRSQ 235
R GHS+ S S+
Sbjct: 2249 GRRGSGHSESSDSE 2262
Score = 40.0 bits (92), Expect = 0.003
Identities = 52/236 (22%), Positives = 76/236 (32%), Gaps = 39/236 (16%)
Query: 42 TNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKS 101
T+ + R HS S Q+ R G+S + S G
Sbjct: 1997 THGQTADTTRHGHSG-HGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAG 2055
Query: 102 GQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENH---H 158
QH +G + E+ + ++ G Q G+ G E + H
Sbjct: 2056 SQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQ-RGSRTAGRRGSGHSESSDSEVH 2114
Query: 159 SERSRNHLERSLSQSDRSQ-------------------GQLKRH----HPQY----ERSH 191
S S H + Q+ RSQ G RH H Q R+
Sbjct: 2115 SGVSHTHSGHTYGQA-RSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTT 2173
Query: 192 GQYKRSHGQSERSHGHSERSHGHSERSHGHSERSH------GHSKRSRSQGDLVDT 241
G+ + SH +S S HSE S HS +H + H GH ++ + G DT
Sbjct: 2174 GRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDT 2229
Score = 39.7 bits (91), Expect = 0.003
Identities = 58/285 (20%), Positives = 95/285 (33%), Gaps = 53/285 (18%)
Query: 41 GTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRG--------YSRCRSNSEEGNHDKKP 92
G E ++ + ++ + + S Q S +H G S + S G H
Sbjct: 1140 GFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDS 1199
Query: 93 SQKPS----GFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEE 148
Q G SGQ GQ +Q + + E GQ+ S+ +S +
Sbjct: 1200 GQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQ 1259
Query: 149 SQGQPEENHHSERSRN-----HLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSER 203
+ + S +S N H + S S+ Q H+P +S +R G +
Sbjct: 1260 TGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYP---KSGSTVRRRQGTTHG 1316
Query: 204 SHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQ 263
G + R HGHS SR+ G + SD
Sbjct: 1317 QRGDTTR--------HGHSGHGQSTQTGSRTSGRQRFSHSD------------------- 1349
Query: 264 RDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSER--HQRYST 306
AT ++ ++ +Q+G HG+SE H+R+ T
Sbjct: 1350 ----ATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHET 1390
Score = 38.9 bits (89), Expect = 0.006
Identities = 49/235 (20%), Positives = 85/235 (36%), Gaps = 48/235 (20%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
+ T +R+ S+ E+ + HRH +++ G+H K
Sbjct: 1256 QSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSE-----HIHTQAGSHYPKSGSTVRRR 1310
Query: 100 KSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHS 159
+ H G + + + Q+ + ++ G Q S + SE G H
Sbjct: 1311 QGTTHGQRG----DTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQ 1366
Query: 160 ERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRS-------HGQS---------ER 203
E++ + ++ SQ S+ + H ++E ++GQ + HGQS R
Sbjct: 1367 EQTHS---QAGSQHGESESTV---HERHETTYGQTGEATGHGHSGHGQSTQRGSRTTGRR 1420
Query: 204 SHGHSER--SHGHS---------ERSHGHSERSHG------HSKRSRSQGDLVDT 241
GHSE S HS E++HG + HG H + + G DT
Sbjct: 1421 GSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDT 1475
Score = 37.4 bits (85), Expect = 0.017
Identities = 55/191 (28%), Positives = 78/191 (40%), Gaps = 23/191 (12%)
Query: 58 ESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPL-NGQPLIEQEK 116
ES SRQ S +H G S+ + G S++ SGF GQH L +GQ +
Sbjct: 535 ESRSRQSSYG---QHGSGSSQSSGYGQYG------SRETSGF--GQHGLGSGQSTGFGQY 583
Query: 117 CSDNYEA----QAEKNQGQSEG-NQHQSE-GNPDKSEESQGQPEEN---HHSERSRNHLE 167
S + ++ Q GQS G QH+S G + S G + + H R +
Sbjct: 584 GSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFG 643
Query: 168 RSLSQSDRSQGQLKRHHPQYERS-HGQYKRSHGQSERSHGHSERSHGHSERSHGH-SERS 225
+ S S +S G + + S GQ+ GQS H RS S HG S +S
Sbjct: 644 QHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQS 703
Query: 226 HGHSKRSRSQG 236
G+ + S G
Sbjct: 704 SGYGQHGSSSG 714
Score = 37.0 bits (84), Expect = 0.023
Identities = 38/213 (17%), Positives = 68/213 (31%), Gaps = 32/213 (15%)
Query: 54 HSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIE 113
HS+ S + RH+ + + +E G+ + + +G+ +
Sbjct: 1901 HSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSD 1960
Query: 114 QEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQS 173
E S + GQ+ G+ + G+ + + + +S +
Sbjct: 1961 SEGPSGVSHTHSGHTHGQA-GSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRG 2019
Query: 174 DRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHG-------------------- 213
R+ G+ H +Y S G SH S +HG + HG
Sbjct: 2020 SRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDT 2079
Query: 214 --HSERSHGHS---------ERSHGHSKRSRSQ 235
H+ HG S R GHS+ S S+
Sbjct: 2080 TRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSE 2112
Score = 36.2 bits (82), Expect = 0.039
Identities = 55/207 (26%), Positives = 69/207 (33%), Gaps = 42/207 (20%)
Query: 59 SPSRQQSKAHRHRHRRGYS----RCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQ 114
S S Q S +H R G S +S+ + + S++ SGF GQH
Sbjct: 750 SGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF--GQHGSGSSQ---- 803
Query: 115 EKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSD 174
S + Q GQS G G+ S GQ E H H S S
Sbjct: 804 ---STGF-GQYGSGSGQSAGFGQHGSGSGQSS--GFGQHESRSHQSSYGQHGSGSSQSSG 857
Query: 175 RSQ-----------GQLKRHHPQYERSHGQYKRSHGQSER--SHG-----------HSER 210
Q GQ + QY GQ+ GQS HG H R
Sbjct: 858 YGQHGSSSGQTSGFGQHRSSSGQYS-GFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESR 916
Query: 211 SHGHSERSHGH-SERSHGHSKRSRSQG 236
SH S HG S +S G+ + S G
Sbjct: 917 SHQSSYGQHGSGSSQSSGYGQHGSSSG 943
Score = 34.7 bits (78), Expect = 0.11
Identities = 56/229 (24%), Positives = 78/229 (34%), Gaps = 35/229 (15%)
Query: 41 GTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFK 100
G E ++++ ++ + S S Q S +H G + S G H + S + SGF
Sbjct: 1063 GFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQT-----SGFGQH-RPGSGQSSGFG 1116
Query: 101 -----SGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQH-----QSEGNPDKSEESQ 150
SGQ GQ K S AQ E GQS QH QS G S
Sbjct: 1117 QYGSGSGQSSGFGQHGSGTGKSSGF--AQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSG 1174
Query: 151 GQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQY--------------KR 196
H S N SD Q QY GQ
Sbjct: 1175 PTTSFGQHVSGSDNFSSSGQHISDSGQST---GFGQYGSGSGQSTGLGQGESQQVESGST 1231
Query: 197 SHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDL 245
HG+ E +HG + + HS+ G S ++ R R ++ S++
Sbjct: 1232 VHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEV 1280
Score = 34.3 bits (77), Expect = 0.15
Identities = 40/189 (21%), Positives = 65/189 (34%), Gaps = 7/189 (3%)
Query: 54 HSKKESPSRQQSKAHRHRHRRGY---SRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQP 110
H + +R H + G R RS+ E + + S+ H G
Sbjct: 2148 HGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSR 2207
Query: 111 LIEQEKCSDNYEAQAEKNQGQSEGNQHQSEG-NPDKSEESQGQPEENH-HSERSRNHLER 168
+ + G + + H G + + + G+ H S S H
Sbjct: 2208 HGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWG 2267
Query: 169 SLSQSDRSQGQLKRHHPQYERS-HGQYKRSHGQSERSHGHSERSHGHSERSHGHSER-SH 226
S + S QGQ Q + HG+ + +HGQ+ + H +G S ++ S R SH
Sbjct: 2268 SHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASH 2327
Query: 227 GHSKRSRSQ 235
S S Q
Sbjct: 2328 FQSHSSERQ 2336
Score = 32.0 bits (71), Expect = 0.73
Identities = 43/178 (24%), Positives = 61/178 (34%), Gaps = 41/178 (23%)
Query: 57 KESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEK 116
KE SK HR HR + EE + ++ + G KSG
Sbjct: 91 KEYCKASGSKKHRRGHR--------HQEEESETEEDEEDTPGHKSGY------------- 129
Query: 117 CSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRS 176
++ SEG +H S S+G + H S R + +LS S
Sbjct: 130 ----------RHSSWSEGEEHGYS-----SGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQ 174
Query: 177 QGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRS 234
+G KR+H RS + S G+ +R S +SH R G S S
Sbjct: 175 EGSQKRYH----RSSCGHSWSGGK-DRHGSSSVELRERINKSHISPSRESGEEYESGS 227
Score = 29.3 bits (64), Expect = 4.7
Identities = 41/205 (20%), Positives = 80/205 (39%), Gaps = 25/205 (12%)
Query: 36 YKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHR--HRRGYSRCRSNSEEGNHDKKPS 93
++E E E+E++ + S S + + H + H RG +CR S ++ +
Sbjct: 108 HQEEESETEEDEEDTPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGN 167
Query: 94 QKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQS---EGNQHQSEGNPDKSEESQ 150
SG + G Q + C ++ +++ S ++S +P + +
Sbjct: 168 LSSSGNQEG-----SQKRYHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEE 222
Query: 151 GQPEENHHSERSRNH------LERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQS-ER 203
+ +S + H LE S +S+ +Q +++ E+ G G S R
Sbjct: 223 YESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIR------EQKLGSSCSGSGDSGRR 276
Query: 204 SH--GHSERSHGHSERSHGHSERSH 226
SH G+S S ++ S +SH
Sbjct: 277 SHACGYSNSSGCGRPQNASSSCQSH 301
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 53.1 bits (126), Expect = 3e-07
Identities = 45/204 (22%), Positives = 84/204 (41%), Gaps = 12/204 (5%)
Query: 38 ELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHR-------RGYSRCRSNSEEGNHDK 90
E E + E K R + S S SR SK+H R R R ++R RS ++ K
Sbjct: 294 EPESGKSNERKGGR-SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 352
Query: 91 KPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ 150
P +K S KS + + ++K D E EK + + + + + E ++ +E +
Sbjct: 353 SPHKKRS--KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 410
Query: 151 GQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSER 210
++ ER ++ + + DR + + K H ++ + + + E+
Sbjct: 411 RGKNKDRDKEREKDREKDK--EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEID 468
Query: 211 SHGHSERSHGHSERSHGHSKRSRS 234
++ RS+ S+RSRS
Sbjct: 469 EKRKKDKKSRTPPRSYNASRRSRS 492
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/218 (18%), Positives = 91/218 (41%), Gaps = 14/218 (6%)
Query: 46 EEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHP 105
+ +++ N S+ R++SK+ + + R +S S + DK+ + K +
Sbjct: 332 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK-IKEKERV 390
Query: 106 LNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNH 165
E+E+ + E + E+ + + + + + DK ++ + + E+ H +R +
Sbjct: 391 KEKDREKEREREKER-EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 166 LERSLSQSDRSQGQLKRHHPQYE---------RSHGQYKRSHGQSERSHGHSERSHGHSE 216
+ + +R + + K + + RS+ +RS S RS S
Sbjct: 450 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 509
Query: 217 RSHGHSER--SHGHSKRSRSQGDLV-DTQSDLIATQRD 251
R+ +R S S RSR++ D + + D I+ +R+
Sbjct: 510 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRE 547
Score = 37.0 bits (84), Expect = 0.023
Identities = 30/145 (20%), Positives = 55/145 (37%), Gaps = 13/145 (8%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESP-------SRQQSKAHRHRHRRGYSRCRSNSEEGNHD 89
KE E ++E KR+ K +P R +S + R RR S RS
Sbjct: 457 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 516
Query: 90 KKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEES 149
+K S+ PS + ++EK D+ + E+ + S +K E++
Sbjct: 517 RKSSRSPSPRSRNKKDK------KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 570
Query: 150 QGQPEENHHSERSRNHLERSLSQSD 174
+E H++ + + + + D
Sbjct: 571 STSLKEKEHNKEPDSSVSKEVDDKD 595
Score = 30.4 bits (67), Expect = 2.1
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 173 SDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHG-HSERSHGHSERSHGHSERSHG-HSK 230
++R G+ + H RS +SH + +RS H RSH S RS H K
Sbjct: 301 NERKGGRSRSHTRSKSRSSS---KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 357
Query: 231 RSRSQ 235
RS+S+
Sbjct: 358 RSKSR 362
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 53.1 bits (126), Expect = 3e-07
Identities = 45/204 (22%), Positives = 84/204 (41%), Gaps = 12/204 (5%)
Query: 38 ELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHR-------RGYSRCRSNSEEGNHDK 90
E E + E K R + S S SR SK+H R R R ++R RS ++ K
Sbjct: 178 EPESGKSNERKGGR-SRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 236
Query: 91 KPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQ 150
P +K S KS + + ++K D E EK + + + + + E ++ +E +
Sbjct: 237 SPHKKRS--KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKE 294
Query: 151 GQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSER 210
++ ER ++ + + DR + + K H ++ + + + E+
Sbjct: 295 RGKNKDRDKEREKDREKDK--EKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEID 352
Query: 211 SHGHSERSHGHSERSHGHSKRSRS 234
++ RS+ S+RSRS
Sbjct: 353 EKRKKDKKSRTPPRSYNASRRSRS 376
Score = 48.1 bits (113), Expect = 1e-05
Identities = 41/218 (18%), Positives = 91/218 (41%), Gaps = 14/218 (6%)
Query: 46 EEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHP 105
+ +++ N S+ R++SK+ + + R +S S + DK+ + K +
Sbjct: 216 KHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREK-IKEKERV 274
Query: 106 LNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNH 165
E+E+ + E + E+ + + + + + DK ++ + + E+ H +R +
Sbjct: 275 KEKDREKEREREKER-EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 166 LERSLSQSDRSQGQLKRHHPQYE---------RSHGQYKRSHGQSERSHGHSERSHGHSE 216
+ + +R + + K + + RS+ +RS S RS S
Sbjct: 334 EKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSP 393
Query: 217 RSHGHSER--SHGHSKRSRSQGDLV-DTQSDLIATQRD 251
R+ +R S S RSR++ D + + D I+ +R+
Sbjct: 394 RTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRE 431
Score = 37.0 bits (84), Expect = 0.023
Identities = 30/145 (20%), Positives = 55/145 (37%), Gaps = 13/145 (8%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESP-------SRQQSKAHRHRHRRGYSRCRSNSEEGNHD 89
KE E ++E KR+ K +P R +S + R RR S RS
Sbjct: 341 KEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 400
Query: 90 KKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEES 149
+K S+ PS + ++EK D+ + E+ + S +K E++
Sbjct: 401 RKSSRSPSPRSRNKKDK------KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 454
Query: 150 QGQPEENHHSERSRNHLERSLSQSD 174
+E H++ + + + + D
Sbjct: 455 STSLKEKEHNKEPDSSVSKEVDDKD 479
Score = 30.4 bits (67), Expect = 2.1
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 5/65 (7%)
Query: 173 SDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHG-HSERSHGHSERSHGHSERSHG-HSK 230
++R G+ + H RS +SH + +RS H RSH S RS H K
Sbjct: 185 NERKGGRSRSHTRSKSRSSS---KSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKK 241
Query: 231 RSRSQ 235
RS+S+
Sbjct: 242 RSKSR 246
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 52.0 bits (123), Expect = 7e-07
Identities = 43/253 (16%), Positives = 100/253 (39%), Gaps = 7/253 (2%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKP 96
+E EG E+E + + Q K + + + G +++ ++
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE 247
Query: 97 SGFKSGQHPLNGQP--LIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPE 154
+ + + Q + EQE+ E Q K + Q+E Q E ++ E+ + Q E
Sbjct: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE----QEEQTGEQEEQMREQEE 303
Query: 155 ENHHSERSRNHLERSLSQSDRSQG-QLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHG 213
+ E E + + + G Q ++ Q E+ Q ++ Q E+ E+
Sbjct: 304 QMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363
Query: 214 HSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQRDL 273
E+ E+ ++ R Q + + Q + + Q++ + QK+ + Q + + Q++
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQ 423
Query: 274 IVTQRDLVATERD 286
+ Q + + +++
Sbjct: 424 MRKQEEHMGEQKE 436
Score = 50.1 bits (118), Expect = 3e-06
Identities = 41/199 (20%), Positives = 68/199 (34%), Gaps = 11/199 (5%)
Query: 113 EQEKCSDNYEAQAEKNQGQ---SEGNQHQSEGNPDKSE----ESQGQPEENHHSERSRNH 165
EQE E Q + +GQ EG + EG + E E +GQ E R +
Sbjct: 70 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 129
Query: 166 LERSLSQSDRSQ-GQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSER 224
R R Q GQ++ Q GQ + GQ G G G
Sbjct: 130 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Query: 225 SHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATE 284
G Q + Q + + Q + + Q++ + Q + + Q + + Q + V +
Sbjct: 190 QEGQMGEQEGQ---MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQ 246
Query: 285 RDLINQSGRSHGQSERHQR 303
+ + + + E R
Sbjct: 247 EEQVQKQEEQMRKQEEQMR 265
Score = 39.3 bits (90), Expect = 0.005
Identities = 35/189 (18%), Positives = 59/189 (31%), Gaps = 12/189 (6%)
Query: 111 LIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSL 170
L+E EK + K + +++ EG + E +GQ E R +
Sbjct: 22 LVETEKSEIQLHIKELKRKLETDKIPLPQEG---QVREQEGQVREQEGQVREQE------ 72
Query: 171 SQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSK 230
Q +GQ++ Q GQ + GQ G G G G +
Sbjct: 73 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 132
Query: 231 RSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQ 290
Q V Q + Q + Q+ + Q + Q + Q V + + +
Sbjct: 133 EQEGQ---VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE 189
Query: 291 SGRSHGQSE 299
G+ E
Sbjct: 190 QEGQMGEQE 198
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 52.0 bits (123), Expect = 7e-07
Identities = 58/234 (24%), Positives = 90/234 (38%), Gaps = 12/234 (5%)
Query: 75 GYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEG 134
G S+ +E NH +K + + N + + + Q E+ + Q E
Sbjct: 155 GPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEER 214
Query: 135 NQHQSEGNPDKSEESQGQPEENHHSE--------RSRNHLERSLSQSDRSQGQLKRHHPQ 186
+ Q E ++ E + Q E E R R H ER Q +R Q +R Q
Sbjct: 215 LREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQ 274
Query: 187 YERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLI 246
ER H Q +R Q ER ER ER ER +R R Q + + Q L
Sbjct: 275 EERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLP 334
Query: 247 ATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSER 300
+R L +K L +R +++ ++ + L+ +L+ Q R Q ER
Sbjct: 335 GQERLLEEVEKLLEQERRQ---EEQERLLERERLLEEVEELLEQE-RLRQQDER 384
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 52.0 bits (123), Expect = 7e-07
Identities = 38/202 (18%), Positives = 77/202 (38%), Gaps = 20/202 (9%)
Query: 38 ELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPS 97
E+EG EE K +R+ ++ ++ + EEG +++ +
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEE--------------EEGEGEEEEGEG-K 857
Query: 98 GFKSGQHPLNGQPLIEQEKCSDNYEAQAE-KNQGQSEGNQHQSEGNPDKSEESQGQPEEN 156
G + G+ + E E + E + E + +G+ EG + + EG ++ E +G+ EE
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917
Query: 157 HHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH-SERSHGHS 215
+ + +G+ + + E G+++ G+ E G E G
Sbjct: 918 EGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWE---GEEEEGEGEGEEEGEGEG 974
Query: 216 ERSHGHSERSHGHSKRSRSQGD 237
E G E G + +G+
Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGE 996
Score = 51.6 bits (122), Expect = 9e-07
Identities = 38/206 (18%), Positives = 85/206 (41%), Gaps = 12/206 (5%)
Query: 36 YKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQK 95
+++ E E++K + + E ++ ++ + R G + + E+G H K+ +Q+
Sbjct: 669 WQDEEREKGEKDKGRGEMERPGEG-EKELAEKEEWKKRDGEEQEQKEREQG-HQKERNQE 726
Query: 96 PSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEE 155
+ G +G+ +E+ D E + ++ +G+ EG + EG +K E + + E
Sbjct: 727 ---MEEGGEEEHGEG---EEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780
Query: 156 NHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHG----QSERSHGHSERS 211
E+ ++ + + ++G+ + E G+ + G + E G E
Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG 840
Query: 212 HGHSERSHGHSERSHGHSKRSRSQGD 237
G E G E G + +G+
Sbjct: 841 EGEEEEGEGEEEEGEGKGEEEGEEGE 866
Score = 45.4 bits (106), Expect = 6e-05
Identities = 42/210 (20%), Positives = 73/210 (34%), Gaps = 28/210 (13%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKP 96
+E EG E E+ K + KKE + ++ K + EE + ++
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQG------EGEEEETEGRGEEKEE 810
Query: 97 SGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEEN 156
G G G+ E+E E + E + + EG + + EG + EE +G+ EE
Sbjct: 811 GGEVEGGEVEEGKGEREEE------EEEGEGEEEEGEGEEEEGEG---EEEEGEGKGEEE 861
Query: 157 HHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQ---SERSHGHSERSHG 213
E + + +G+ + E G+ + G+ E G E G
Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGE----EEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917
Query: 214 ------HSERSHGHSERSHGHSKRSRSQGD 237
E G E G + +G+
Sbjct: 918 EGKGEEEGEEGEGEGEEEEGEGEGEDGEGE 947
Score = 42.0 bits (97), Expect = 7e-04
Identities = 38/208 (18%), Positives = 75/208 (36%), Gaps = 7/208 (3%)
Query: 37 KELEGTNAEEE---KNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPS 93
+E EG EEE + + + + E + G EG +
Sbjct: 889 EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEG 948
Query: 94 QKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQP 153
++ G G+ G+ E+E + E + E + + EG + EG + EE +G+
Sbjct: 949 EEEEGEWEGEEE-EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007
Query: 154 EENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHG 213
E E + + +G+ + + E + + ++ R+ E G
Sbjct: 1008 EGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEG 1067
Query: 214 -HSERSHGHSERSHG--HSKRSRSQGDL 238
+ E +ER G + K S+ +G +
Sbjct: 1068 KYQETGEEENERQDGEEYKKVSKIKGSV 1095
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 51.6 bits (122), Expect = 9e-07
Identities = 49/224 (21%), Positives = 76/224 (33%), Gaps = 20/224 (8%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
+E K H KK+ ++S H+ +H+ S +E G KK ++
Sbjct: 666 KERSGKSHRHKKKKK--HKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSA 723
Query: 105 PLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQS----EGNPDKSEESQGQPEENHHSE 160
P + + + E A + + + +Q +S EG+ K +E G H
Sbjct: 724 PADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGG 783
Query: 161 RS------------RNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQ--SERSHG 206
R R +RS S RSQ SH +++S Q E
Sbjct: 784 RKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEE 843
Query: 207 HSERSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQR 250
S H S G SH S+RS S + + QR
Sbjct: 844 DSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQR 887
Score = 48.9 bits (115), Expect = 6e-06
Identities = 53/217 (24%), Positives = 84/217 (38%), Gaps = 20/217 (9%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQ-----------SKAHRHRHRRGYSRCRSNS-- 83
K G +++ K +++ +K +P+ + S A R RR + S
Sbjct: 701 KAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLP 760
Query: 84 -EEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGN 142
EEG+ KK + G S H G+ + S K +S S G+
Sbjct: 761 AEEGSSGKK-DEGGGGSSSQDH--GGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGD 817
Query: 143 PDKSEESQGQPEENHHSERSRNHLER-SLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQS 201
D + S + + S+ S E S S+ RS+ + R H + S Y S S
Sbjct: 818 EDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDAS 877
Query: 202 ERSHGHSERSHGHSERSHG-HSERSHGHSKRSRSQGD 237
+S R +S+ S+ +S+RS HSKRS D
Sbjct: 878 SDQSCYS-RQRSYSDDSYSDYSDRSRRHSKRSHDSDD 913
Score = 44.7 bits (104), Expect = 1e-04
Identities = 45/202 (22%), Positives = 75/202 (37%), Gaps = 11/202 (5%)
Query: 41 GTNAEEEKNKR-QNHSKKES-PSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPS--QKP 96
G+ A + +R Q+ S++ S P+ + S + G S + + PS Q+
Sbjct: 739 GSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRR 798
Query: 97 SGFK-SGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEE 155
+G K S + QP E D + + + + E + + S+ +
Sbjct: 799 AGTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGR 858
Query: 156 NHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHS 215
H S RS S S + Q R + S+ Y S+RS HS+RSH
Sbjct: 859 RHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDY------SDRSRRHSKRSHDSD 912
Query: 216 ERSHGHSERSHGHSKRSRSQGD 237
+ + S+ K S S D
Sbjct: 913 DSDYASSKHRSKRHKYSSSDDD 934
Score = 44.7 bits (104), Expect = 1e-04
Identities = 45/192 (23%), Positives = 81/192 (42%), Gaps = 14/192 (7%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
EEE++ HS+ S S RH R R S+S + + D+ + + +
Sbjct: 840 EEEEDSGSEHSRSRSRS-----GRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSY 894
Query: 105 -PLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHS-ERS 162
+ + ++ D+ ++ ++ +S+ +++ S + SQ + H+ ERS
Sbjct: 895 SDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERS 954
Query: 163 RNHLERSLSQSDRSQGQLKRHHP---QYERSHGQYKRSHGQSERSHGHSERSHGHSERSH 219
R+ S RS+ + + ++RS Y R +S RS S+RS G +RS
Sbjct: 955 RSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSR-SYSRDRSRSTRS--PSQRS-GSRKRSW 1010
Query: 220 GHSERSHGHSKR 231
GH HS R
Sbjct: 1011 GHESPEERHSGR 1022
Score = 43.5 bits (101), Expect = 2e-04
Identities = 48/202 (23%), Positives = 86/202 (42%), Gaps = 14/202 (6%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKP 96
K+ G + + + + H + PS Q +A R R R + +S + + D S +
Sbjct: 769 KDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASSHRL 828
Query: 97 SGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEEN 156
Q+ E+E+ S + +++ G+ + S + S S +++
Sbjct: 829 HQKSPSQYSEE-----EEEEDSGSEHSRSRSRSGRRHSSHRSSRRS--YSSSSDASSDQS 881
Query: 157 HHSERSRNHLERSLSQ-SDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHS 215
+S R R++ + S S SDRS+ KR H + Y S +S+R H +S +S
Sbjct: 882 CYS-RQRSYSDDSYSDYSDRSRRHSKRSH---DSDDSDYASSKHRSKR-HKYSSSDDDYS 936
Query: 216 ERSHGHSERSHGHSK-RSRSQG 236
RS H++ RSRS+G
Sbjct: 937 LSCSQSRSRSRSHTRERSRSRG 958
>gi|9945320 cyclin L1 [Homo sapiens]
Length = 526
Score = 50.8 bits (120), Expect = 2e-06
Identities = 34/159 (21%), Positives = 63/159 (39%), Gaps = 13/159 (8%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++ K R + S S SR +S++ H RR Y+ RS S + + + +H
Sbjct: 381 KDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRH 440
Query: 105 PLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRN 164
+G P ++ + D+ ++ N+H G+ K S+ Q + HS+ ++
Sbjct: 441 HNHGSPHLKAKHTRDDLKSS----------NRH---GHKRKKSRSRSQSKSRDHSDAAKK 487
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSER 203
H DR + + HG + HG+ R
Sbjct: 488 HRHERGHHRDRRERSRSFERSHKSKHHGGSRSGHGRHRR 526
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/190 (22%), Positives = 66/190 (34%), Gaps = 39/190 (20%)
Query: 56 KKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQE 115
KKE RQQ+ + Y+ R +S+ + + S+ S +S
Sbjct: 362 KKEPEDRQQAS------KSPYNGVRKDSKRSRNSRSASRSRSRTRSR------------- 402
Query: 116 KCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDR 175
S ++ + N +S + S S + HH+ S HL+ ++ D
Sbjct: 403 --SRSHTPRRHYNNRRSRSGTYSSRSR--SRSRSHSESPRRHHNHGSP-HLKAKHTRDDL 457
Query: 176 SQGQLKRHHPQYERSHGQYK-RSHGQSERSHGHSERSH-------------GHSERSHGH 221
H + RS Q K R H + + H H ER H H + HG
Sbjct: 458 KSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRH-ERGHHRDRRERSRSFERSHKSKHHGG 516
Query: 222 SERSHGHSKR 231
S HG +R
Sbjct: 517 SRSGHGRHRR 526
Score = 39.7 bits (91), Expect = 0.003
Identities = 31/141 (21%), Positives = 53/141 (37%), Gaps = 15/141 (10%)
Query: 109 QPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLER 168
+P Q+ Y + ++ + +S P ++++ RSR+
Sbjct: 364 EPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYS 423
Query: 169 SLSQS-DRSQGQLKRHHPQYERSH--GQYKRSHGQSERSHGHSE-----------RSHGH 214
S S+S RS + R H + H ++ R +S HGH R H
Sbjct: 424 SRSRSRSRSHSESPRRHHNHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQSKSRDHSD 483
Query: 215 SERSHGHSERSHGHSKRSRSQ 235
+ + H H ER H +R RS+
Sbjct: 484 AAKKHRH-ERGHHRDRRERSR 503
Score = 38.5 bits (88), Expect = 0.008
Identities = 41/154 (26%), Positives = 57/154 (37%), Gaps = 27/154 (17%)
Query: 98 GFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENH 157
GF P + + + +EK + + K + + +S N + +
Sbjct: 333 GFSPASKPSSPREVKAEEKSPISINVKTVKKEPEDRQQASKSPYNGVRKD---------- 382
Query: 158 HSERSRNHLERSLSQS---DRSQGQLKRHHPQYERSH-GQYKRSHGQSERSHGHSERSH- 212
S+RSRN S S+S RS+ R H RS G Y RSH S R H
Sbjct: 383 -SKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGTYSSRSRSRSRSHSESPRRHH 441
Query: 213 ----GHSERSHGH----SERSHGHSK---RSRSQ 235
H + H S HGH + RSRSQ
Sbjct: 442 NHGSPHLKAKHTRDDLKSSNRHGHKRKKSRSRSQ 475
Score = 37.7 bits (86), Expect = 0.013
Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 7/68 (10%)
Query: 42 TNAEEEKNKRQNHSKKESPSRQQSK-------AHRHRHRRGYSRCRSNSEEGNHDKKPSQ 94
T + + + R H +K+S SR QSK A +HRH RG+ R R S+
Sbjct: 453 TRDDLKSSNRHGHKRKKSRSRSQSKSRDHSDAAKKHRHERGHHRDRRERSRSFERSHKSK 512
Query: 95 KPSGFKSG 102
G +SG
Sbjct: 513 HHGGSRSG 520
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/213 (20%), Positives = 86/213 (40%), Gaps = 13/213 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++E+ +R +KE +R++ AH R YS S +P ++ G+
Sbjct: 179 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 238
Query: 105 PLNGQPLIEQEKCSDNYE-AQAEKNQGQSEGNQHQS-EGNPDKSEESQGQPEENHHSERS 162
P+ + + E++ SD + + +E+ +E + +S G+ ++ EE + + EE SE S
Sbjct: 239 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 298
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH--------SERSHGH 214
E + + + + Q + + S + + H +R G
Sbjct: 299 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 358
Query: 215 SERSHGHSERSHGHSKRSR-SQGDLVDTQSDLI 246
SE + E G + S ++GD V L+
Sbjct: 359 SEEA--EEEVGEGTPQSSALTEGDYVPDSPALL 389
Score = 30.8 bits (68), Expect = 1.6
Identities = 22/118 (18%), Positives = 51/118 (43%), Gaps = 17/118 (14%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
E + EE+ + + ++E + ++S+ SNSEE +
Sbjct: 273 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE----------- 321
Query: 100 KSGQHPLNGQPLIEQEKCSDNY-----EAQAEKNQGQS-EGNQHQSEGNPDKSEESQG 151
+S + + ++E+ ++N+ E++ +++ G+S E + EG P S ++G
Sbjct: 322 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEG 379
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/213 (20%), Positives = 86/213 (40%), Gaps = 13/213 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++E+ +R +KE +R++ AH R YS S +P ++ G+
Sbjct: 189 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 248
Query: 105 PLNGQPLIEQEKCSDNYE-AQAEKNQGQSEGNQHQS-EGNPDKSEESQGQPEENHHSERS 162
P+ + + E++ SD + + +E+ +E + +S G+ ++ EE + + EE SE S
Sbjct: 249 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 308
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH--------SERSHGH 214
E + + + + Q + + S + + H +R G
Sbjct: 309 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Query: 215 SERSHGHSERSHGHSKRSR-SQGDLVDTQSDLI 246
SE + E G + S ++GD V L+
Sbjct: 369 SEEA--EEEVGEGTPQSSALTEGDYVPDSPALL 399
Score = 34.3 bits (77), Expect = 0.15
Identities = 51/252 (20%), Positives = 94/252 (37%), Gaps = 46/252 (18%)
Query: 16 NHPSRKKVNFLDMSL-DDIIIYKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRR 74
N P R++ + D DD + K + + +E+ + R++ +KE K H H
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKE-------KCRHHSH-- 114
Query: 75 GYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEG 134
++E G H + K +H + EQ+K +E Q + +
Sbjct: 115 -------SAEGGKHAR--------VKEREHERRKRHREEQDKARREWERQKRREMAR--- 156
Query: 135 NQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQY 194
E S+ + + ER R ER + + + Q + K R+ +
Sbjct: 157 ------------EHSRRERDRLEQLERKRER-ERKMREQQKEQREQKERE---RRAEERR 200
Query: 195 KRSHGQSERSHGHSERSHGHSER-SHGHSERSHGHSKRSRSQ-GDLVDTQSDLIATQRDL 252
K + E S H +S++ H RS R R + GD + +RDL
Sbjct: 201 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 260
Query: 253 IATQKDLIATQR 264
++ +D+ ++R
Sbjct: 261 LSDLQDISDSER 272
Score = 30.8 bits (68), Expect = 1.6
Identities = 22/118 (18%), Positives = 51/118 (43%), Gaps = 17/118 (14%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
E + EE+ + + ++E + ++S+ SNSEE +
Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE----------- 331
Query: 100 KSGQHPLNGQPLIEQEKCSDNY-----EAQAEKNQGQS-EGNQHQSEGNPDKSEESQG 151
+S + + ++E+ ++N+ E++ +++ G+S E + EG P S ++G
Sbjct: 332 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEG 389
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/199 (21%), Positives = 74/199 (37%), Gaps = 14/199 (7%)
Query: 46 EEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHP 105
++K +++ HS+ S SR++ RHRR SR R S + ++ S+ P +S
Sbjct: 240 DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRE 299
Query: 106 LNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNH 165
G+ K D + EK + ++ P KS + + R R
Sbjct: 300 -RGRRSRSTSKTRDKKKEDKEKKRSKT----------PPKSYSTARRSRSASRERRRRRS 348
Query: 166 LERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERS 225
+ S + K R H + K+ ERS ERS ++S ++
Sbjct: 349 RSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKS---KDKE 405
Query: 226 HGHSKRSRSQGDLVDTQSD 244
++S S D+ D
Sbjct: 406 KDRERKSESDKDVKQVTRD 424
Score = 40.8 bits (94), Expect = 0.002
Identities = 33/177 (18%), Positives = 63/177 (35%), Gaps = 6/177 (3%)
Query: 48 KNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLN 107
+++R++HSK S R +S R H R R RS S DKK K K + P
Sbjct: 272 RSRRRSHSKSRSRRRSKSPRRRRSHSRERGR-RSRSTSKTRDKKKEDKEK--KRSKTPPK 328
Query: 108 GQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLE 167
+ + + + G + +S P + P + ++ E
Sbjct: 329 SYSTARRSRSASRERRRRRSRSGTRSPKKPRS---PKRKLSRSPSPRRHKKEKKKDKDKE 385
Query: 168 RSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSER 224
RS + +RS + K+ + + + + + + + E G+ E+
Sbjct: 386 RSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEK 442
Score = 32.3 bits (72), Expect = 0.56
Identities = 20/92 (21%), Positives = 35/92 (38%), Gaps = 5/92 (5%)
Query: 143 PDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSE 202
PDK EE + H RSR+ R+ S S + + + + +S + + +
Sbjct: 239 PDKKEEKR-----RHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRR 293
Query: 203 RSHGHSERSHGHSERSHGHSERSHGHSKRSRS 234
RSH S ++ KRS++
Sbjct: 294 RSHSRERGRRSRSTSKTRDKKKEDKEKKRSKT 325
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 50.1 bits (118), Expect = 3e-06
Identities = 38/201 (18%), Positives = 81/201 (40%), Gaps = 16/201 (7%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKP 96
+E E +E K +R++ KKE R++ K R + R+ E G +KK +K
Sbjct: 41 REREIETRKEGKKERESERKKERREREKRKREREKERK--------RERGKKEKKGERK- 91
Query: 97 SGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEEN 156
+ + +++ + E + K + + E + EG ++ + + + EE
Sbjct: 92 ------KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGK-ERERKEERKREER 144
Query: 157 HHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSE 216
ER + E+ + +R + + K+ + E + ++ + ER+ ++ E
Sbjct: 145 KERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKE 204
Query: 217 RSHGHSERSHGHSKRSRSQGD 237
R ER ++ Q D
Sbjct: 205 RRERKKERKKKEERKKERQKD 225
Score = 46.2 bits (108), Expect = 4e-05
Identities = 43/203 (21%), Positives = 77/203 (37%), Gaps = 28/203 (13%)
Query: 37 KELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKP 96
+E E E EK +++ KKE ++ K R R +R + EE KK +K
Sbjct: 64 REREKRKREREKERKRERGKKEKKG-ERKKEERERKKRRREKENKEGEEKEKRKKKEKKE 122
Query: 97 SGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKS----EESQGQ 152
G S + + E+ K + E + +K + + E + + + K EE + +
Sbjct: 123 RGRTSKEGKERERK--EERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Query: 153 PEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSH 212
E +R RN ER + + + + K+ ER + ++ Q +R E+
Sbjct: 181 KERKERKKRERNRKERKKERERKERRERKK-----ERKKKEERKKERQKDRQTNWREKER 235
Query: 213 GHSERSHGHSERSHGHSKRSRSQ 235
G KR R +
Sbjct: 236 G----------------KRERKE 242
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 50.1 bits (118), Expect = 3e-06
Identities = 42/206 (20%), Positives = 84/206 (40%), Gaps = 13/206 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++E+ +R +KE +R++ AH R YS S +P ++ G+
Sbjct: 180 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 239
Query: 105 PLNGQPLIEQEKCSDNYE-AQAEKNQGQSEGNQHQS-EGNPDKSEESQGQPEENHHSERS 162
P+ + + E++ SD + + +E+ +E + +S G+ ++ EE + + EE SE S
Sbjct: 240 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 299
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH--------SERSHGH 214
E + + + + Q + + S + + H +R G
Sbjct: 300 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 359
Query: 215 SERSHGHSERSHGHSKRSR-SQGDLV 239
SE + E G + S ++GD V
Sbjct: 360 SEEA--EEEVGEGTPQSSALTEGDYV 383
Score = 33.1 bits (74), Expect = 0.33
Identities = 32/186 (17%), Positives = 68/186 (36%), Gaps = 12/186 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++EK K + H++ + R+ + RHR + +R E K+ + +H
Sbjct: 101 KDEKRKEKKHARVKEKEREHERRKRHREEQDKAR-----REWERQKRREM------AREH 149
Query: 105 PLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRN 164
+ +EQ + E + + Q + + + ++ +E + + E + H R
Sbjct: 150 SRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 209
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERSHGQYK-RSHGQSERSHGHSERSHGHSERSHGHSE 223
+ S S+ + ++E G+ + ER + SER +E
Sbjct: 210 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAE 269
Query: 224 RSHGHS 229
S S
Sbjct: 270 SSSAES 275
Score = 30.8 bits (68), Expect = 1.6
Identities = 22/118 (18%), Positives = 51/118 (43%), Gaps = 17/118 (14%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
E + EE+ + + ++E + ++S+ SNSEE +
Sbjct: 274 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE----------- 322
Query: 100 KSGQHPLNGQPLIEQEKCSDNY-----EAQAEKNQGQS-EGNQHQSEGNPDKSEESQG 151
+S + + ++E+ ++N+ E++ +++ G+S E + EG P S ++G
Sbjct: 323 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEG 380
Score = 29.3 bits (64), Expect = 4.7
Identities = 21/114 (18%), Positives = 40/114 (35%), Gaps = 21/114 (18%)
Query: 145 KSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERS 204
+ ++ + + EE +R +N +R + +G+L+ H + + Y+R +R
Sbjct: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
Query: 205 HG------------------HSERSHGHSERSHG---HSERSHGHSKRSRSQGD 237
H + E+ H ER H KR R + D
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 131
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 50.1 bits (118), Expect = 3e-06
Identities = 42/206 (20%), Positives = 84/206 (40%), Gaps = 13/206 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++E+ +R +KE +R++ AH R YS S +P ++ G+
Sbjct: 189 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 248
Query: 105 PLNGQPLIEQEKCSDNYE-AQAEKNQGQSEGNQHQS-EGNPDKSEESQGQPEENHHSERS 162
P+ + + E++ SD + + +E+ +E + +S G+ ++ EE + + EE SE S
Sbjct: 249 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 308
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH--------SERSHGH 214
E + + + + Q + + S + + H +R G
Sbjct: 309 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Query: 215 SERSHGHSERSHGHSKRSR-SQGDLV 239
SE + E G + S ++GD V
Sbjct: 369 SEEA--EEEVGEGTPQSSALTEGDYV 392
Score = 31.6 bits (70), Expect = 0.95
Identities = 30/178 (16%), Positives = 61/178 (34%), Gaps = 19/178 (10%)
Query: 145 KSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERS 204
+ ++ + + EE +R +N +R + +G+L+ H + + Y+R +R
Sbjct: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRG 77
Query: 205 HG------------------HSERSHGHSERSHGH-SERSHGHSKRSRSQGDLVDTQSDL 245
H + E+ H E+ H +R R + + + +
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREW 137
Query: 246 IATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSERHQR 303
+R +A + D + RD + ER + Q Q ER +R
Sbjct: 138 ERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQKERERR 195
Score = 30.8 bits (68), Expect = 1.6
Identities = 31/186 (16%), Positives = 66/186 (35%), Gaps = 3/186 (1%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++EK K + H++ + R+ + R RHR + R E + + +
Sbjct: 101 KDEKRKEKKHARVKEKEREHER--RKRHREEQDKARREWERQKRREMAREHSRRERGNDG 158
Query: 105 PLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRN 164
+ +EQ + E + + Q + + + ++ +E + + E + H R
Sbjct: 159 VCLFRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 218
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERSHGQYK-RSHGQSERSHGHSERSHGHSERSHGHSE 223
+ S S+ + ++E G+ + ER + SER +E
Sbjct: 219 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAE 278
Query: 224 RSHGHS 229
S S
Sbjct: 279 SSSAES 284
Score = 30.8 bits (68), Expect = 1.6
Identities = 22/118 (18%), Positives = 51/118 (43%), Gaps = 17/118 (14%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
E + EE+ + + ++E + ++S+ SNSEE +
Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE----------- 331
Query: 100 KSGQHPLNGQPLIEQEKCSDNY-----EAQAEKNQGQS-EGNQHQSEGNPDKSEESQG 151
+S + + ++E+ ++N+ E++ +++ G+S E + EG P S ++G
Sbjct: 332 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEG 389
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 50.1 bits (118), Expect = 3e-06
Identities = 42/206 (20%), Positives = 84/206 (40%), Gaps = 13/206 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++E+ +R +KE +R++ AH R YS S +P ++ G+
Sbjct: 157 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 216
Query: 105 PLNGQPLIEQEKCSDNYE-AQAEKNQGQSEGNQHQS-EGNPDKSEESQGQPEENHHSERS 162
P+ + + E++ SD + + +E+ +E + +S G+ ++ EE + + EE SE S
Sbjct: 217 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 276
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH--------SERSHGH 214
E + + + + Q + + S + + H +R G
Sbjct: 277 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 336
Query: 215 SERSHGHSERSHGHSKRSR-SQGDLV 239
SE + E G + S ++GD V
Sbjct: 337 SEEA--EEEVGEGTPQSSALTEGDYV 360
Score = 37.0 bits (84), Expect = 0.023
Identities = 49/252 (19%), Positives = 93/252 (36%), Gaps = 44/252 (17%)
Query: 16 NHPSRKKVNFLDMSL-DDIIIYKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRR 74
N P R++ + D DD + K + + +E+ + R++ +KE + HR
Sbjct: 30 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKE------KRRHRSHSAE 83
Query: 75 GYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEG 134
G R +E H+++ + EQ+K +E Q + +
Sbjct: 84 GGKHARVKEKEREHERRKRHRE----------------EQDKARREWERQKRREMAR--- 124
Query: 135 NQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQY 194
E S+ + + ER R ER + + + Q + K R+ +
Sbjct: 125 ------------EHSRRERDRLEQLERKRER-ERKMREQQKEQREQKERE---RRAEERR 168
Query: 195 KRSHGQSERSHGHSERSHGHSER-SHGHSERSHGHSKRSRSQ-GDLVDTQSDLIATQRDL 252
K + E S H +S++ H RS R R + GD + +RDL
Sbjct: 169 KEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDL 228
Query: 253 IATQKDLIATQR 264
++ +D+ ++R
Sbjct: 229 LSDLQDISDSER 240
Score = 30.8 bits (68), Expect = 1.6
Identities = 22/118 (18%), Positives = 51/118 (43%), Gaps = 17/118 (14%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
E + EE+ + + ++E + ++S+ SNSEE +
Sbjct: 251 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE----------- 299
Query: 100 KSGQHPLNGQPLIEQEKCSDNY-----EAQAEKNQGQS-EGNQHQSEGNPDKSEESQG 151
+S + + ++E+ ++N+ E++ +++ G+S E + EG P S ++G
Sbjct: 300 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEG 357
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 50.1 bits (118), Expect = 3e-06
Identities = 42/206 (20%), Positives = 84/206 (40%), Gaps = 13/206 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++E+ +R +KE +R++ AH R YS S +P ++ G+
Sbjct: 146 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 205
Query: 105 PLNGQPLIEQEKCSDNYE-AQAEKNQGQSEGNQHQS-EGNPDKSEESQGQPEENHHSERS 162
P+ + + E++ SD + + +E+ +E + +S G+ ++ EE + + EE SE S
Sbjct: 206 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 265
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH--------SERSHGH 214
E + + + + Q + + S + + H +R G
Sbjct: 266 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 325
Query: 215 SERSHGHSERSHGHSKRSR-SQGDLV 239
SE + E G + S ++GD V
Sbjct: 326 SEEA--EEEVGEGTPQSSALTEGDYV 349
Score = 33.1 bits (74), Expect = 0.33
Identities = 32/186 (17%), Positives = 68/186 (36%), Gaps = 12/186 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++EK K + H++ + R+ + RHR + +R E K+ + +H
Sbjct: 67 KDEKRKEKKHARVKEKEREHERRKRHREEQDKAR-----REWERQKRREM------AREH 115
Query: 105 PLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRN 164
+ +EQ + E + + Q + + + ++ +E + + E + H R
Sbjct: 116 SRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE 175
Query: 165 HLERSLSQSDRSQGQLKRHHPQYERSHGQYK-RSHGQSERSHGHSERSHGHSERSHGHSE 223
+ S S+ + ++E G+ + ER + SER +E
Sbjct: 176 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAE 235
Query: 224 RSHGHS 229
S S
Sbjct: 236 SSSAES 241
Score = 30.8 bits (68), Expect = 1.6
Identities = 22/118 (18%), Positives = 51/118 (43%), Gaps = 17/118 (14%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
E + EE+ + + ++E + ++S+ SNSEE +
Sbjct: 240 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE----------- 288
Query: 100 KSGQHPLNGQPLIEQEKCSDNY-----EAQAEKNQGQS-EGNQHQSEGNPDKSEESQG 151
+S + + ++E+ ++N+ E++ +++ G+S E + EG P S ++G
Sbjct: 289 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEG 346
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 50.1 bits (118), Expect = 3e-06
Identities = 42/206 (20%), Positives = 84/206 (40%), Gaps = 13/206 (6%)
Query: 45 EEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGFKSGQH 104
++E+ +R +KE +R++ AH R YS S +P ++ G+
Sbjct: 191 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK 250
Query: 105 PLNGQPLIEQEKCSDNYE-AQAEKNQGQSEGNQHQS-EGNPDKSEESQGQPEENHHSERS 162
P+ + + E++ SD + + +E+ +E + +S G+ ++ EE + + EE SE S
Sbjct: 251 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 310
Query: 163 RNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGH--------SERSHGH 214
E + + + + Q + + S + + H +R G
Sbjct: 311 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 370
Query: 215 SERSHGHSERSHGHSKRSR-SQGDLV 239
SE + E G + S ++GD V
Sbjct: 371 SEEA--EEEVGEGTPQSSALTEGDYV 394
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/266 (20%), Positives = 100/266 (37%), Gaps = 23/266 (8%)
Query: 22 KVNFLDMSLDDIIIYKELEG-TNAEEEKNKRQNHSKKESPSRQQSKAHRHR---HRRGYS 77
KV LD L + KE E + KN SK++S + + HR Y
Sbjct: 9 KVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYR 68
Query: 78 RCRSNSEEGNHDK----KPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSE 133
R S + G D KP Q+ S + H + + ++ S + E + E
Sbjct: 69 REDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE 128
Query: 134 GNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERS---LSQSDRSQGQLKRHHPQYERS 190
+ + + ++ ++++ + E E +R H R L Q +R + + ++ Q +
Sbjct: 129 REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQ 188
Query: 191 HGQYKRSHGQSER-----------SHGHSERSHGHSERSHGHSERSHGHSKRSRSQ-GDL 238
Q +R ER +H + R + H RS R R + GD
Sbjct: 189 REQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDG 248
Query: 239 VDTQSDLIATQRDLIATQKDLIATQR 264
+ +RDL++ +D+ ++R
Sbjct: 249 RKPVKEEKMEERDLLSDLQDISDSER 274
Score = 30.8 bits (68), Expect = 1.6
Identities = 22/118 (18%), Positives = 51/118 (43%), Gaps = 17/118 (14%)
Query: 40 EGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRGYSRCRSNSEEGNHDKKPSQKPSGF 99
E + EE+ + + ++E + ++S+ SNSEE +
Sbjct: 285 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASE----------- 333
Query: 100 KSGQHPLNGQPLIEQEKCSDNY-----EAQAEKNQGQS-EGNQHQSEGNPDKSEESQG 151
+S + + ++E+ ++N+ E++ +++ G+S E + EG P S ++G
Sbjct: 334 QSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEG 391
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.123 0.342
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,944,360
Number of Sequences: 37866
Number of extensions: 651409
Number of successful extensions: 7232
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 224
Number of HSP's successfully gapped in prelim test: 426
Number of HSP's that attempted gapping in prelim test: 3913
Number of HSP's gapped (non-prelim): 2149
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.