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Search of human proteins with 7705682
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7705682 geminin [Homo sapiens]
(209 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7705682 geminin [Homo sapiens] 411 e-115
gi|50083293 coiled-coil domain containing 123 [Homo sapiens] 43 2e-04
gi|219803769 trichoplein [Homo sapiens] 40 0.001
gi|14150056 trichoplein [Homo sapiens] 40 0.001
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 40 0.002
gi|9910266 kinesin family member 15 [Homo sapiens] 40 0.002
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 39 0.002
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 39 0.003
gi|189027048 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens] 39 0.004
gi|189027046 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens] 39 0.004
gi|14670375 SCG10-like-protein [Homo sapiens] 38 0.007
gi|15149463 caldesmon 1 isoform 4 [Homo sapiens] 37 0.009
gi|15149467 caldesmon 1 isoform 3 [Homo sapiens] 37 0.009
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 37 0.009
gi|21450721 enkurin [Homo sapiens] 37 0.012
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 37 0.012
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 37 0.012
gi|23238244 sorting nexin 16 isoform a [Homo sapiens] 37 0.016
gi|23238246 sorting nexin 16 isoform a [Homo sapiens] 37 0.016
gi|23238248 sorting nexin 16 isoform b [Homo sapiens] 37 0.016
gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens] 37 0.016
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 37 0.016
gi|42740907 clusterin isoform 2 [Homo sapiens] 36 0.021
gi|42716297 clusterin isoform 1 [Homo sapiens] 36 0.021
gi|38044112 restin isoform b [Homo sapiens] 36 0.021
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 36 0.021
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 36 0.021
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 36 0.021
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 36 0.021
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 36 0.021
>gi|7705682 geminin [Homo sapiens]
Length = 209
Score = 411 bits (1056), Expect = e-115
Identities = 209/209 (100%), Positives = 209/209 (100%)
Query: 1 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 60
MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS
Sbjct: 1 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 60
Query: 61 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 120
TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL
Sbjct: 61 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 120
Query: 121 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET 180
HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET
Sbjct: 121 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET 180
Query: 181 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI 209
VEDSLVEDSEIGTCAEGTVSSSTDAKPCI
Sbjct: 181 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI 209
>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
Length = 783
Score = 42.7 bits (99), Expect = 2e-04
Identities = 47/209 (22%), Positives = 85/209 (40%), Gaps = 39/209 (18%)
Query: 4 SMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRE---------------------- 41
+MKQ +E++ +K +R LK + ++S + E
Sbjct: 263 TMKQAMKELQLKLKGMEKEKRKLKEAEKASSQEVAAPELLYLRKQAQELVDENDGLKMTV 322
Query: 42 NELSAGLSKRKHRNDHLTSTTS-------SPGVIVPESSENKNLGGVTQESFDLMIKENP 94
+ L+ LS+ + + HL+ S S G I P + K L + D+M +++
Sbjct: 323 HRLNVELSRYQTKFRHLSKEESLNIEGLPSKGPIPPWLLDIKYLSPLLLAYEDMMKEKDE 382
Query: 95 SSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAEL 154
+ KE R + E +KENE+LH+E L K + +E +Q A+L
Sbjct: 383 LNATLKEEMRMFRMRVQEVVKENEELHQE----------LNKSSAVTSEEWRQLQTQAKL 432
Query: 155 IERLNGEPLDNFESLDNQEFDSEEETVED 183
+ N L+ E + DS +E +++
Sbjct: 433 VLEENKLLLEQLEIQQRKAKDSHQERLQE 461
>gi|219803769 trichoplein [Homo sapiens]
Length = 498
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 97 QYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIE 156
Q +E E+ R+A E+LK E+L + +E+ E+AR +KE E + A + A++ E
Sbjct: 385 QQIQEKIEQNRRAQEESLKHREQLIRNLEEV-RELARREKEESEKLKSARKQELEAQVAE 443
Query: 157 RLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEIGTCAEGTVSSSTDAKP 207
R L +E+ D QE + EEE + D+ + AE KP
Sbjct: 444 R----RLQAWEA-DQQEEEEEEEARRVEQLSDALLQQEAETMAEQGYRPKP 489
>gi|14150056 trichoplein [Homo sapiens]
Length = 498
Score = 40.4 bits (93), Expect = 0.001
Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 6/111 (5%)
Query: 97 QYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIE 156
Q +E E+ R+A E+LK E+L + +E+ E+AR +KE E + A + A++ E
Sbjct: 385 QQIQEKIEQNRRAQEESLKHREQLIRNLEEV-RELARREKEESEKLKSARKQELEAQVAE 443
Query: 157 RLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEIGTCAEGTVSSSTDAKP 207
R L +E+ D QE + EEE + D+ + AE KP
Sbjct: 444 R----RLQAWEA-DQQEEEEEEEARRVEQLSDALLQQEAETMAEQGYRPKP 489
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 39.7 bits (91), Expect = 0.002
Identities = 26/124 (20%), Positives = 57/124 (45%), Gaps = 11/124 (8%)
Query: 66 GVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKAL----------YEALK 115
G + + +N+ L + +E + +++ +++ W E AE RR+ L AL
Sbjct: 481 GQLQAQVQDNEGLSRLNREQEERLLELERAAELWGEQAEARRQILETMQNDRTTISRALS 540
Query: 116 ENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESL-DNQEF 174
+N +L +++ + + +L EN E+ + Q++ + + GE + L + E
Sbjct: 541 QNRELKEQLAELQSGFVKLTNENMEITSALQSEQHVKRELGKKLGELQEKLSELKETVEL 600
Query: 175 DSEE 178
S+E
Sbjct: 601 KSQE 604
Score = 33.1 bits (74), Expect = 0.17
Identities = 41/194 (21%), Positives = 82/194 (42%), Gaps = 10/194 (5%)
Query: 7 QKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSSPG 66
Q +EE KE + R L+ + G LV + EL L+ +H +
Sbjct: 197 QLEEEKKECHQKQGALREQLQ-VHIQTIGILVSEKAELQTALAHTQHAARQKEGESEDLA 255
Query: 67 VIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKR---RKALYEALKENEKLHKE 123
+ S + +G + + + ++ + +Y KE+ ++R R LY+ + NE L +E
Sbjct: 256 SRLQYS--RRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNEDLKQE 313
Query: 124 IEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLD-NQEFDSEEETVE 182
+ + ++ L E + E +Q E+ E L + E+ D NQ+ ++ +E
Sbjct: 314 KSELEEKLRVLVTEKAGMQLNLEELQKKLEMTELLLQQFSSRCEAPDANQQL---QQAME 370
Query: 183 DSLVEDSEIGTCAE 196
+ ++ +G E
Sbjct: 371 ERAQLEAHLGQVME 384
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 39.7 bits (91), Expect = 0.002
Identities = 39/151 (25%), Positives = 64/151 (42%), Gaps = 18/151 (11%)
Query: 2 NPSMKQKQEE-IKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 60
N +K +QEE IKE + S + LKM E+ + L ++ +T
Sbjct: 1239 NQQLKNEQEESIKERLAKSKIVEEMLKMKADL---------EEVQSALYNKEMECLRMTD 1289
Query: 61 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 120
+ ++ + K + + M +E + E+ K+ + L E EN KL
Sbjct: 1290 EVERTQTLESKAFQEKEQ---LRSKLEEMYEERERTSQEMEMLRKQVECLAE---ENGKL 1343
Query: 121 --HKEIEQKDNEIARLKKENKELAEVAEHVQ 149
H+ + QK + RLKKEN LAE E ++
Sbjct: 1344 VGHQNLHQKIQYVVRLKKENVRLAEETEKLR 1374
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 39.3 bits (90), Expect = 0.002
Identities = 49/211 (23%), Positives = 87/211 (41%), Gaps = 22/211 (10%)
Query: 5 MKQKQEEIKENIK-----NSSVPRRTLKMIQPSASGSLVGRE--------NELSAGLSKR 51
+KQ Q++I E +K N V TLK+ Q + L + N L +
Sbjct: 768 LKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQL 827
Query: 52 KHRNDHLTSTTSSPGVIVPE-SSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKAL 110
K N+HL + E E ++ G +E D + E QY+ + + + + L
Sbjct: 828 KQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQDQLEAE----QYFSTLYKTQVREL 883
Query: 111 YEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLD 170
E +E KL KE++QK E L+ E LA E A+ + + + L+
Sbjct: 884 KEECEEKTKLGKELQQKKQE---LQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLE 940
Query: 171 NQEFDSEEETVEDSLVEDSEIGTCAEGTVSS 201
++ E E +++ + + T + T++S
Sbjct: 941 KEKIMKELE-IKEMMARHKQELTEKDATIAS 970
Score = 29.3 bits (64), Expect = 2.5
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 6/63 (9%)
Query: 115 KENEKLHKEI----EQKDNEIARLKKENKEL-AEVAEHVQYMAELIERLNGEPLDNFESL 169
KEN KLH E+ E+ ++ + +KE E+ A++AE Q EL L+ + D E L
Sbjct: 1061 KENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSD-IEQL 1119
Query: 170 DNQ 172
+Q
Sbjct: 1120 RSQ 1122
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 38.9 bits (89), Expect = 0.003
Identities = 41/149 (27%), Positives = 65/149 (43%), Gaps = 32/149 (21%)
Query: 4 SMKQKQEEIKENIKNSSVPRRTLK------MIQPSASGSLVGRENELSAGLSKRKHRNDH 57
SM +K ++ E + V +TLK A V +NE+S+GL K D
Sbjct: 909 SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGL---KQNYDE 965
Query: 58 LTSTTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKEN 117
+ S G I E Q FDL+ KEN E+R++ L AL
Sbjct: 966 M----SPAGQISKEE---------LQHEFDLLKKEN----------EQRKRKLQAALINR 1002
Query: 118 EKLHKEIEQKDNEIARLKKENKELAEVAE 146
++L + + + + E+A LK E+K+ ++E
Sbjct: 1003 KELLQRVSRLEEELANLKDESKKEIPLSE 1031
Score = 32.0 bits (71), Expect = 0.39
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 7/91 (7%)
Query: 105 KRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAEL-----IERLN 159
++ + + EA EN KL +EI + + L EN +L AE +QY +L I+
Sbjct: 2493 EKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD--AELIQYREDLNQVITIKDSQ 2550
Query: 160 GEPLDNFESLDNQEFDSEEETVEDSLVEDSE 190
+ L + N+E +++ +E+ L E E
Sbjct: 2551 QKQLLEVQLQQNKELENKYAKLEEKLKESEE 2581
Score = 30.8 bits (68), Expect = 0.86
Identities = 35/134 (26%), Positives = 57/134 (42%), Gaps = 10/134 (7%)
Query: 81 VTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKE 140
V QE +L K + KE ++ ++A E + EK+ K + K +I L++EN
Sbjct: 1639 VRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDR 1698
Query: 141 L-AEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEE--------ETVEDSLVED-SE 190
L AEV E +E L E L+ + + E + +DSL E+ +
Sbjct: 1699 LRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQD 1758
Query: 191 IGTCAEGTVSSSTD 204
+ EG VS +
Sbjct: 1759 LKHQIEGNVSKQAN 1772
Score = 30.4 bits (67), Expect = 1.1
Identities = 32/108 (29%), Positives = 50/108 (46%), Gaps = 19/108 (17%)
Query: 100 KEVAEKRRKALY---EALKENEKLHKEIEQKDNEIARLKK-----------ENKELAEVA 145
+++ K + AL EALKEN+ L +E+ I RL K +NKE V
Sbjct: 1479 QQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTVL 1538
Query: 146 EHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVE---DSLVEDSE 190
+ + E ++L E +D L+NQ S E+++ + L ED E
Sbjct: 1539 GRLALLQEERDKLITE-MDR-SLLENQSLSSSCESLKLALEGLTEDKE 1584
>gi|189027048 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens]
Length = 643
Score = 38.5 bits (88), Expect = 0.004
Identities = 49/195 (25%), Positives = 86/195 (44%), Gaps = 29/195 (14%)
Query: 6 KQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSA-GLSKRKHRNDHLTSTTSS 64
+Q+ EE KEN KN+ +G L E ++ S R+ DH +
Sbjct: 325 EQEMEEAKENFKNA-------------LTGILTQFEQIVAVFNASTRQKAWDHFSKAQRK 371
Query: 65 PGVIVPESSE------NKNLGGVT-QESFDLMIKENPSSQYWK-EVAEKRRKALYEALKE 116
I + SE ++ L G+ +E ++ EN S K V E A ALKE
Sbjct: 372 NIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKE 431
Query: 117 -NEKLHKEIEQKDNEIARLKKENKELAEVAEH------VQYMAELIERLNGEPLDNFESL 169
N+ L +++ NE+ LK+E ++L E+ +Q++ + ++ + + L E L
Sbjct: 432 ENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLTIQEEL 491
Query: 170 DNQEFDSEEETVEDS 184
+N++ + E+ E S
Sbjct: 492 NNKKSELEQAKEEQS 506
>gi|189027046 ecto-NOX disulfide-thiol exchanger 1 [Homo sapiens]
Length = 643
Score = 38.5 bits (88), Expect = 0.004
Identities = 49/195 (25%), Positives = 86/195 (44%), Gaps = 29/195 (14%)
Query: 6 KQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSA-GLSKRKHRNDHLTSTTSS 64
+Q+ EE KEN KN+ +G L E ++ S R+ DH +
Sbjct: 325 EQEMEEAKENFKNA-------------LTGILTQFEQIVAVFNASTRQKAWDHFSKAQRK 371
Query: 65 PGVIVPESSE------NKNLGGVT-QESFDLMIKENPSSQYWK-EVAEKRRKALYEALKE 116
I + SE ++ L G+ +E ++ EN S K V E A ALKE
Sbjct: 372 NIDIWRKHSEELRNAQSEQLMGIRREEEMEMSDDENCDSPTKKMRVDESALAAQAYALKE 431
Query: 117 -NEKLHKEIEQKDNEIARLKKENKELAEVAEH------VQYMAELIERLNGEPLDNFESL 169
N+ L +++ NE+ LK+E ++L E+ +Q++ + ++ + + L E L
Sbjct: 432 ENDSLRWQLDAYRNEVELLKQEKEQLFRTEENLTKDQQLQFLQQTMQGMQQQLLTIQEEL 491
Query: 170 DNQEFDSEEETVEDS 184
+N++ + E+ E S
Sbjct: 492 NNKKSELEQAKEEQS 506
>gi|14670375 SCG10-like-protein [Homo sapiens]
Length = 180
Score = 37.7 bits (86), Expect = 0.007
Identities = 27/86 (31%), Positives = 45/86 (52%), Gaps = 11/86 (12%)
Query: 91 KENPSSQYWKEVAEKR---RKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEH 147
++ +Q K++AE+R R+ L++AL+EN ++ E+K N L KE +E
Sbjct: 96 RKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIRE------- 148
Query: 148 VQYMAELIERLNGEPLDNFESLDNQE 173
++A L ERL + L E N+E
Sbjct: 149 -AHLAALRERLREKELHAAEVRRNKE 173
>gi|15149463 caldesmon 1 isoform 4 [Homo sapiens]
Length = 558
Score = 37.4 bits (85), Expect = 0.009
Identities = 51/226 (22%), Positives = 90/226 (39%), Gaps = 33/226 (14%)
Query: 8 KQEEIK-ENIKNSSVPRRTLKMIQPSASG--SLVGRENELSAGLSKRKHRNDHLTSTTSS 64
K+EEIK E IK P+ +K G + + E H+ H +T S
Sbjct: 224 KKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT------HKLKHTENTFSR 277
Query: 65 PGVIV----------PESSENKNL-------GGVTQESFDLMIKENPSSQYWKEVAEKRR 107
PG P+ K L G E F+ + ++ + E +K+R
Sbjct: 278 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR 337
Query: 108 KALYEALKENEKLHKEIE-----QKDNEIARLKKE-NKELAEVAEHVQYMAELIERLNGE 161
+ + L+E E+ K+ E +++ E RLK+E + AE AE Q M E + +
Sbjct: 338 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 397
Query: 162 PLDNFESLDNQ-EFDSEEETVEDSLVEDSEIGTCAEGTVSSSTDAK 206
P F + + + E + S+ + S + + + + S D++
Sbjct: 398 PFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSR 443
>gi|15149467 caldesmon 1 isoform 3 [Homo sapiens]
Length = 564
Score = 37.4 bits (85), Expect = 0.009
Identities = 51/226 (22%), Positives = 90/226 (39%), Gaps = 33/226 (14%)
Query: 8 KQEEIK-ENIKNSSVPRRTLKMIQPSASG--SLVGRENELSAGLSKRKHRNDHLTSTTSS 64
K+EEIK E IK P+ +K G + + E H+ H +T S
Sbjct: 230 KKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT------HKLKHTENTFSR 283
Query: 65 PGVIV----------PESSENKNL-------GGVTQESFDLMIKENPSSQYWKEVAEKRR 107
PG P+ K L G E F+ + ++ + E +K+R
Sbjct: 284 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR 343
Query: 108 KALYEALKENEKLHKEIE-----QKDNEIARLKKE-NKELAEVAEHVQYMAELIERLNGE 161
+ + L+E E+ K+ E +++ E RLK+E + AE AE Q M E + +
Sbjct: 344 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 403
Query: 162 PLDNFESLDNQ-EFDSEEETVEDSLVEDSEIGTCAEGTVSSSTDAK 206
P F + + + E + S+ + S + + + + S D++
Sbjct: 404 PFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSR 449
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 37.4 bits (85), Expect = 0.009
Identities = 51/226 (22%), Positives = 90/226 (39%), Gaps = 33/226 (14%)
Query: 8 KQEEIK-ENIKNSSVPRRTLKMIQPSASG--SLVGRENELSAGLSKRKHRNDHLTSTTSS 64
K+EEIK E IK P+ +K G + + E H+ H +T S
Sbjct: 459 KKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMT------HKLKHTENTFSR 512
Query: 65 PGVIV----------PESSENKNL-------GGVTQESFDLMIKENPSSQYWKEVAEKRR 107
PG P+ K L G E F+ + ++ + E +K+R
Sbjct: 513 PGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKR 572
Query: 108 KALYEALKENEKLHKEIE-----QKDNEIARLKKE-NKELAEVAEHVQYMAELIERLNGE 161
+ + L+E E+ K+ E +++ E RLK+E + AE AE Q M E + +
Sbjct: 573 EERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKK 632
Query: 162 PLDNFESLDNQ-EFDSEEETVEDSLVEDSEIGTCAEGTVSSSTDAK 206
P F + + + E + S+ + S + + + + S D++
Sbjct: 633 PFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSR 678
>gi|21450721 enkurin [Homo sapiens]
Length = 256
Score = 37.0 bits (84), Expect = 0.012
Identities = 22/78 (28%), Positives = 44/78 (56%), Gaps = 3/78 (3%)
Query: 83 QESFDLMIKENPSSQYWKEVAEKRRKALYEALKEN-EKLHKEIEQKDNEIARLKKE--NK 139
QE +D I+EN K ++++ R+A+ + LK+N E++HKE + I + K+ +
Sbjct: 169 QEDYDRYIQENLKKAAMKRLSDEEREAVLQGLKKNWEEVHKEFQSLSVFIDSIPKKIRKQ 228
Query: 140 ELAEVAEHVQYMAELIER 157
L E + +++ +IE+
Sbjct: 229 RLEEEMKQLEHDIGIIEK 246
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 37.0 bits (84), Expect = 0.012
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 73 SENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIA 132
+ NK + + E DL + EN + Q E + K L + KEN+ L +E Q + +
Sbjct: 774 NSNKKIQQLESELQDLEM-ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKK 832
Query: 133 RLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEI 191
+L+KENK L + AE + + N + N E +N+ E ++S V E+
Sbjct: 833 QLEKENKRLRQQAE----IKDTTLEENNVKIGNLEK-ENKTLSKEIGIYKESCVRLKEL 886
Score = 33.1 bits (74), Expect = 0.17
Identities = 13/47 (27%), Positives = 29/47 (61%)
Query: 115 KENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGE 161
KEN+ LH+ I++ +++++++ E +++ + EH + E E L E
Sbjct: 587 KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENE 633
Score = 32.3 bits (72), Expect = 0.30
Identities = 48/220 (21%), Positives = 86/220 (39%), Gaps = 75/220 (34%)
Query: 4 SMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTS 63
S++ Q K+ +K + +T++ ++ ++ + E E N+HL T S
Sbjct: 520 SLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQE-----------NEHLNQTVS 568
Query: 64 SPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALK-------- 115
S L +Q S + +K+ EK K L+E++K
Sbjct: 569 S-------------LRQRSQISAEARVKD----------IEKENKILHESIKETSSKLSK 605
Query: 116 ---ENEKLHKEI----------EQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGE- 161
E ++ KE+ E+ +NE+ L+KEN+ L + +++ E IE L E
Sbjct: 606 IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQEN 665
Query: 162 ------------PLDNF-------ESLDNQEFDSEEETVE 182
LD+F ESL+ + +EE +E
Sbjct: 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Score = 32.0 bits (71), Expect = 0.39
Identities = 47/190 (24%), Positives = 79/190 (41%), Gaps = 29/190 (15%)
Query: 9 QEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSSPGVI 68
QE+I+ +KN ++ + L + S +++ E GL H + S SPG+
Sbjct: 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERD-GLHFLPHASSSAQSPCGSPGMK 241
Query: 69 VPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKD 128
ES ++ ++ E D K + R+ L E ++ +E+EQ +
Sbjct: 242 RTESRQHLSV-----ELADAKAK-----------IRRLRQELEEKTEQLLDCKQELEQME 285
Query: 129 NEIARLKKENKELAEVAEHVQ-YMAEL---------IERLNGEPLDNFESLDNQEFDSE- 177
E+ RL++EN L A + Y EL +++L E E L + EF
Sbjct: 286 IELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKAR 345
Query: 178 -EETVEDSLV 186
EE ED+ V
Sbjct: 346 VEELKEDNQV 355
Score = 29.3 bits (64), Expect = 2.5
Identities = 43/213 (20%), Positives = 91/213 (42%), Gaps = 28/213 (13%)
Query: 5 MKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGREN-ELSAGLSKRKHRNDHLTSTTS 63
++++ E +++ I N + ++ ++ S + REN +L L K+ L S
Sbjct: 637 LEKENELLQKKITNLKITCEKIEALEQE--NSELERENRKLKKTLDSFKNLTFQLESLEK 694
Query: 64 SPGVIVPESSE-NKNLGGVTQESFDL--MIKENPSSQYWKEVAEKRRKALYEALKENEKL 120
+ E+ E +N+ + S + + EN + KE +K + L + K+ E+L
Sbjct: 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754
Query: 121 ---------------------HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLN 159
+K+I+Q ++E+ L+ EN+ L + E ++ ++ +E+L
Sbjct: 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLE 814
Query: 160 GEPLDNFESLDNQEFDSEE-ETVEDSLVEDSEI 191
E + E D ++ E L + +EI
Sbjct: 815 KENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Score = 29.3 bits (64), Expect = 2.5
Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 11/168 (6%)
Query: 7 QKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSSPG 66
+K E ++ + + + + L+ +++ + E+EL + + +L S
Sbjct: 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK 808
Query: 67 VIVPESSENKNLGGVT---QESFDLMIKENPSSQYWKEVA----EKRRKALYEALKENEK 119
+ ENK+L T ++ + KEN + E+ E+ + KEN+
Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Query: 120 LHKEIEQKDNEIARLK---KENKELAEVAE-HVQYMAELIERLNGEPL 163
L KEI RLK KENKEL + A ++ + L E L E L
Sbjct: 869 LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 37.0 bits (84), Expect = 0.012
Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 73 SENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIA 132
+ NK + + E DL + EN + Q E + K L + KEN+ L +E Q + +
Sbjct: 774 NSNKKIQQLESELQDLEM-ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKK 832
Query: 133 RLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEI 191
+L+KENK L + AE + + N + N E +N+ E ++S V E+
Sbjct: 833 QLEKENKRLRQQAE----IKDTTLEENNVKIGNLEK-ENKTLSKEIGIYKESCVRLKEL 886
Score = 33.1 bits (74), Expect = 0.17
Identities = 13/47 (27%), Positives = 29/47 (61%)
Query: 115 KENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGE 161
KEN+ LH+ I++ +++++++ E +++ + EH + E E L E
Sbjct: 587 KENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENE 633
Score = 32.3 bits (72), Expect = 0.30
Identities = 48/220 (21%), Positives = 86/220 (39%), Gaps = 75/220 (34%)
Query: 4 SMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTS 63
S++ Q K+ +K + +T++ ++ ++ + E E N+HL T S
Sbjct: 520 SLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQE-----------NEHLNQTVS 568
Query: 64 SPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALK-------- 115
S L +Q S + +K+ EK K L+E++K
Sbjct: 569 S-------------LRQRSQISAEARVKD----------IEKENKILHESIKETSSKLSK 605
Query: 116 ---ENEKLHKEI----------EQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGE- 161
E ++ KE+ E+ +NE+ L+KEN+ L + +++ E IE L E
Sbjct: 606 IEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQEN 665
Query: 162 ------------PLDNF-------ESLDNQEFDSEEETVE 182
LD+F ESL+ + +EE +E
Sbjct: 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLE 705
Score = 32.0 bits (71), Expect = 0.39
Identities = 47/190 (24%), Positives = 79/190 (41%), Gaps = 29/190 (15%)
Query: 9 QEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSSPGVI 68
QE+I+ +KN ++ + L + S +++ E GL H + S SPG+
Sbjct: 183 QEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERD-GLHFLPHASSSAQSPCGSPGMK 241
Query: 69 VPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKD 128
ES ++ ++ E D K + R+ L E ++ +E+EQ +
Sbjct: 242 RTESRQHLSV-----ELADAKAK-----------IRRLRQELEEKTEQLLDCKQELEQME 285
Query: 129 NEIARLKKENKELAEVAEHVQ-YMAEL---------IERLNGEPLDNFESLDNQEFDSE- 177
E+ RL++EN L A + Y EL +++L E E L + EF
Sbjct: 286 IELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKAR 345
Query: 178 -EETVEDSLV 186
EE ED+ V
Sbjct: 346 VEELKEDNQV 355
Score = 29.3 bits (64), Expect = 2.5
Identities = 43/213 (20%), Positives = 91/213 (42%), Gaps = 28/213 (13%)
Query: 5 MKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGREN-ELSAGLSKRKHRNDHLTSTTS 63
++++ E +++ I N + ++ ++ S + REN +L L K+ L S
Sbjct: 637 LEKENELLQKKITNLKITCEKIEALEQE--NSELERENRKLKKTLDSFKNLTFQLESLEK 694
Query: 64 SPGVIVPESSE-NKNLGGVTQESFDL--MIKENPSSQYWKEVAEKRRKALYEALKENEKL 120
+ E+ E +N+ + S + + EN + KE +K + L + K+ E+L
Sbjct: 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERL 754
Query: 121 ---------------------HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLN 159
+K+I+Q ++E+ L+ EN+ L + E ++ ++ +E+L
Sbjct: 755 EVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLE 814
Query: 160 GEPLDNFESLDNQEFDSEE-ETVEDSLVEDSEI 191
E + E D ++ E L + +EI
Sbjct: 815 KENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Score = 29.3 bits (64), Expect = 2.5
Identities = 40/168 (23%), Positives = 70/168 (41%), Gaps = 11/168 (6%)
Query: 7 QKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSSPG 66
+K E ++ + + + + L+ +++ + E+EL + + +L S
Sbjct: 749 KKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSK 808
Query: 67 VIVPESSENKNLGGVT---QESFDLMIKENPSSQYWKEVA----EKRRKALYEALKENEK 119
+ ENK+L T ++ + KEN + E+ E+ + KEN+
Sbjct: 809 RLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKT 868
Query: 120 LHKEIEQKDNEIARLK---KENKELAEVAE-HVQYMAELIERLNGEPL 163
L KEI RLK KENKEL + A ++ + L E L E L
Sbjct: 869 LSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
>gi|23238244 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 36.6 bits (83), Expect = 0.016
Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Query: 108 KALYEALKE-NEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNF 166
+A E L+E N +L KE+ +K E+ LK K L+E H+ + I L+ EP
Sbjct: 227 RAFCETLEETNYRLQKELLEKQKEMESLK---KLLSEKQLHIDTLENRIRTLSLEP---E 280
Query: 167 ESLDNQEFDSEE-ETVEDSLVEDSEIGTCAEGTVSSSTDAKPCI 209
ESLD E + E+ VE S +E + E S D KPC+
Sbjct: 281 ESLDVSETEGEQILKVESSALEVDQDVLDEE----SRADNKPCL 320
>gi|23238246 sorting nexin 16 isoform a [Homo sapiens]
Length = 344
Score = 36.6 bits (83), Expect = 0.016
Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Query: 108 KALYEALKE-NEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNF 166
+A E L+E N +L KE+ +K E+ LK K L+E H+ + I L+ EP
Sbjct: 227 RAFCETLEETNYRLQKELLEKQKEMESLK---KLLSEKQLHIDTLENRIRTLSLEP---E 280
Query: 167 ESLDNQEFDSEE-ETVEDSLVEDSEIGTCAEGTVSSSTDAKPCI 209
ESLD E + E+ VE S +E + E S D KPC+
Sbjct: 281 ESLDVSETEGEQILKVESSALEVDQDVLDEE----SRADNKPCL 320
>gi|23238248 sorting nexin 16 isoform b [Homo sapiens]
Length = 315
Score = 36.6 bits (83), Expect = 0.016
Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 12/104 (11%)
Query: 108 KALYEALKE-NEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNF 166
+A E L+E N +L KE+ +K E+ LK K L+E H+ + I L+ EP
Sbjct: 198 RAFCETLEETNYRLQKELLEKQKEMESLK---KLLSEKQLHIDTLENRIRTLSLEP---E 251
Query: 167 ESLDNQEFDSEE-ETVEDSLVEDSEIGTCAEGTVSSSTDAKPCI 209
ESLD E + E+ VE S +E + E S D KPC+
Sbjct: 252 ESLDVSETEGEQILKVESSALEVDQDVLDEE----SRADNKPCL 291
>gi|29171755 PTPRF interacting protein alpha 2 [Homo sapiens]
Length = 1257
Score = 36.6 bits (83), Expect = 0.016
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 17/127 (13%)
Query: 35 GSLVGRENELSAGLSKRKHRNDHLTSTTSSPGVIVPESSENKNLGGVTQESFDLMIKENP 94
G L + EL + K +H + + ++ ES+E L +KE
Sbjct: 439 GQLEEKNQELQRARQREKMNEEHNKRLSDTVDRLLTESNER----------LQLHLKERM 488
Query: 95 SSQYWKEV----AEKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVA---EH 147
++ K V +E RK L E+L + E+L +EIE+ +E+ +LK L E H
Sbjct: 489 AALEEKNVLIQESETFRKNLEESLHDKERLAEEIEKLRSELDQLKMRTGSLIEPTIPRTH 548
Query: 148 VQYMAEL 154
+ AEL
Sbjct: 549 LDTSAEL 555
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 36.6 bits (83), Expect = 0.016
Identities = 44/175 (25%), Positives = 76/175 (43%), Gaps = 32/175 (18%)
Query: 10 EEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSSPGVIV 69
EEI+++ K + LK + SL + +++ A L K++ + L S
Sbjct: 143 EEIEQHNKELCKENQELK----DSCISLQKQNSDMQAELQKKQEELETLQSI-------- 190
Query: 70 PESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDN 129
NK L +L +KE YW+ + ++ + ENEK+ ++Q
Sbjct: 191 -----NKKL--------ELKVKEQ--KDYWETELLQLKEQNQKMSSENEKMGIRVDQLQ- 234
Query: 130 EIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSE--EETVE 182
A+L + KE+ ++ + Q E +E+L E F SL Q D + E+TVE
Sbjct: 235 --AQLSTQEKEMEKLVQGDQDKTEQLEQLKKENDHLFLSLTEQRKDQKKLEQTVE 287
>gi|42740907 clusterin isoform 2 [Homo sapiens]
Length = 449
Score = 36.2 bits (82), Expect = 0.021
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 128 DNEIARLKKE-----NKELAEVAEHVQYMAELIERLNGEP---LDNFESLDNQEFDSEEE 179
DNE+ + + NKE+ V+ + LIE+ N E L N E ++ D+ E
Sbjct: 28 DNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNE 87
Query: 180 TVEDSLVEDSEIGTCAEGTVSSSTDAKPCI 209
T E G C E ++ + KPC+
Sbjct: 88 TRESETKLKELPGVCNETMMALWEECKPCL 117
>gi|42716297 clusterin isoform 1 [Homo sapiens]
Length = 501
Score = 36.2 bits (82), Expect = 0.021
Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 8/90 (8%)
Query: 128 DNEIARLKKE-----NKELAEVAEHVQYMAELIERLNGEP---LDNFESLDNQEFDSEEE 179
DNE+ + + NKE+ V+ + LIE+ N E L N E ++ D+ E
Sbjct: 80 DNELQEMSNQGSKYVNKEIQNAVNGVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNE 139
Query: 180 TVEDSLVEDSEIGTCAEGTVSSSTDAKPCI 209
T E G C E ++ + KPC+
Sbjct: 140 TRESETKLKELPGVCNETMMALWEECKPCL 169
>gi|38044112 restin isoform b [Homo sapiens]
Length = 1392
Score = 36.2 bits (82), Expect = 0.021
Identities = 43/167 (25%), Positives = 73/167 (43%), Gaps = 24/167 (14%)
Query: 6 KQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELS------AGLSKRKHRNDHLT 59
K+K E+++ ++ S+ + L++ S ++ E +L+ A L +R N
Sbjct: 435 KRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG 494
Query: 60 STTSSPGVIVPESSENKNLGGVTQESFDLMI---KENPSSQYWKEVAEKRRKALYEALKE 116
S ++ SS + L VT+ I KE+ ++ +E +K KALY A
Sbjct: 495 DVDMSLSLLQEISSLQEKLE-VTRTDHQREITSLKEHFGAR--EETHQKEIKALYTA--- 548
Query: 117 NEKLHKEIEQKDNEIARLKKENKEL---------AEVAEHVQYMAEL 154
EKL KE E +++ KEN ++ +A H Q M EL
Sbjct: 549 TEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL 595
Score = 32.0 bits (71), Expect = 0.39
Identities = 39/188 (20%), Positives = 84/188 (44%), Gaps = 25/188 (13%)
Query: 7 QKQEEIKENIKNS--SVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTSTTSS 64
QK EE + + N + +R K I+ A + +S + ++ L +
Sbjct: 1151 QKLEEERSVLNNQLLEMKKRESKFIK-DADEEKASLQKSISITSALLTEKDAELEKLRNE 1209
Query: 65 PGVIVPESSENKNLGGVTQ-------------ESFDLMIKENPSSQYWKEVAEKRRKALY 111
V+ E++ K+L V Q ++ +L +KEN ++++
Sbjct: 1210 VTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENK-----RQLSSSSGNTDT 1264
Query: 112 EALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDN 171
+A ++ +I+ ++ I L+++N++L V+ M+E NG+ L+N++S D+
Sbjct: 1265 QADEDERAQESQIDFLNSVIVDLQRKNQDLKM---KVEMMSEAALNGNGDDLNNYDS-DD 1320
Query: 172 QEFDSEEE 179
QE S+++
Sbjct: 1321 QEKQSKKK 1328
Score = 30.8 bits (68), Expect = 0.86
Identities = 48/201 (23%), Positives = 80/201 (39%), Gaps = 23/201 (11%)
Query: 6 KQKQEEIKENIKNSSVPRRT-LKMIQPSASGSLVGRENELSAGLSKRKHRNDH------L 58
K K EEI +N++ + + LK + SG L E EL K K +
Sbjct: 991 KTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELE-ELRKQADKAKAAQTAEDAMQIM 1049
Query: 59 TSTTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSS----QYWKEVAEKRRKALYEAL 114
T + + K Q D + + N + KE+ + + E
Sbjct: 1050 EQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFR 1109
Query: 115 KENEKLHKEIEQKDNEIARLKKENKELA--------EVAEHVQYMAELIERLNGEPLD-- 164
KE E L + QK +++ L++EN +LA EV H Q + E LN + L+
Sbjct: 1110 KEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSH-QKLEEERSVLNNQLLEMK 1168
Query: 165 NFESLDNQEFDSEEETVEDSL 185
ES ++ D E+ +++ S+
Sbjct: 1169 KRESKFIKDADEEKASLQKSI 1189
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 36.2 bits (82), Expect = 0.021
Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 15/107 (14%)
Query: 100 KEVAEKRRK------ALYEALKENEKLHKEIEQKDNEIARLKKENKELA----EVAEHVQ 149
KE+ E R K L+E LK+ + L E Q D +I +L +EN +L+ E A H+Q
Sbjct: 276 KELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQ 335
Query: 150 YMAELIERLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEIGTCAE 196
+ + + L E S QE+ ++ +E L + C E
Sbjct: 336 QLQDALNELTEE-----HSKATQEWLEKQAQLEKELSAALQDKKCLE 377
Score = 29.3 bits (64), Expect = 2.5
Identities = 17/58 (29%), Positives = 34/58 (58%), Gaps = 5/58 (8%)
Query: 91 KENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHV 148
KE + Y ++ ++ K Y+A K+ ++E++++ + +L+KENKEL AE +
Sbjct: 1603 KEQAAEHY--KLQMEKAKTHYDAKKQQ---NQELQEQLRSLEQLQKENKELRAEAERL 1655
Score = 28.1 bits (61), Expect = 5.6
Identities = 28/122 (22%), Positives = 59/122 (48%), Gaps = 16/122 (13%)
Query: 100 KEVAEKRRKALYEALKENEK----LHKEIEQKDNEIARLKKENKELAEVAE-----HVQY 150
K+ A++++ L + L++ E+ L ++EQ + + + +++ KE+AE E H Q
Sbjct: 525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQ 584
Query: 151 MAELIE------RLNGEPLDNFESLDNQEFDSEEETVEDSLVEDSEIGTCAEGTVSSSTD 204
+A E R L E+L+ +E ++ E ++ L +E A+ +V+ +
Sbjct: 585 LATAAEEREASLRERDAALKQLEALE-KEKAAKLEILQQQLQVANEARDSAQTSVTQAQR 643
Query: 205 AK 206
K
Sbjct: 644 EK 645
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 36.2 bits (82), Expect = 0.021
Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 12/85 (14%)
Query: 106 RRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDN 165
R +L + K+N K K ++ + EI L+ + + E+ + + Y LD
Sbjct: 59 RLPSLNKLRKQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITY------------LDG 106
Query: 166 FESLDNQEFDSEEETVEDSLVEDSE 190
F+ DN+ DSEEE ED +D E
Sbjct: 107 FDQEDNEAPDSEEEDDEDGDEDDEE 131
Score = 28.5 bits (62), Expect = 4.3
Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Query: 104 EKRRKALYEALKENEKLHKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPL 163
E R++++E L++ L +Q+DNE ++E+ E + + + E P
Sbjct: 88 EDYRESIFELLQQITYLDG-FDQEDNEAPDSEEEDDEDGDEDDEEE------EENEAGPP 140
Query: 164 DNFESLDNQEFDSEEETVEDSLVEDSEIG 192
+ +E + +E + +E+ ED SE+G
Sbjct: 141 EGYEEEEEEEEEEDEDEDEDEDEAGSELG 169
>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
Length = 237
Score = 36.2 bits (82), Expect = 0.021
Identities = 39/189 (20%), Positives = 75/189 (39%), Gaps = 16/189 (8%)
Query: 10 EEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKR--KHRNDHLTSTTSSPGV 67
EE+KE ++ S +L E +++ K KHR L+ + SS
Sbjct: 32 EEVKEQLEKKK-----------KGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKK 80
Query: 68 IVPESSENKNLG---GVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEI 124
+ E K G + S D + S K+ ++R+K + K +E E
Sbjct: 81 RQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSET 140
Query: 125 EQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVEDS 184
E + + KK++K+ E + ++ +++ + + + + ESL E+ E +
Sbjct: 141 ESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK 200
Query: 185 LVEDSEIGT 193
E+ E T
Sbjct: 201 SSEEREKAT 209
>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
Length = 247
Score = 36.2 bits (82), Expect = 0.021
Identities = 39/189 (20%), Positives = 75/189 (39%), Gaps = 16/189 (8%)
Query: 10 EEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKR--KHRNDHLTSTTSSPGV 67
EE+KE ++ S +L E +++ K KHR L+ + SS
Sbjct: 42 EEVKEQLEKKK-----------KGSKALAEFEEKMNENWKKELEKHREKLLSGSESSSKK 90
Query: 68 IVPESSENKNLG---GVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEI 124
+ E K G + S D + S K+ ++R+K + K +E E
Sbjct: 91 RQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSET 150
Query: 125 EQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVEDS 184
E + + KK++K+ E + ++ +++ + + + + ESL E+ E +
Sbjct: 151 ESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKK 210
Query: 185 LVEDSEIGT 193
E+ E T
Sbjct: 211 SSEEREKAT 219
>gi|21071077 dishevelled-associated activator of morphogenesis 1
[Homo sapiens]
Length = 1078
Score = 36.2 bits (82), Expect = 0.021
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 15/100 (15%)
Query: 70 PESS--ENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKEIEQK 127
P+S+ EN N+ V + +++ EN Q WKE AEK RK E ++ EK +E + K
Sbjct: 422 PDSTPLENFNIKNVVR----MLVNENEVKQ-WKEQAEKMRKEHNELQQKLEKKERECDAK 476
Query: 128 DNEIARL--------KKENKELAEVAEHVQYMAELIERLN 159
E + +K KE E + Q +A+L +L+
Sbjct: 477 TQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLTAQLH 516
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.303 0.122 0.322
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,760,279
Number of Sequences: 37866
Number of extensions: 343575
Number of successful extensions: 3124
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 395
Number of HSP's that attempted gapping in prelim test: 2381
Number of HSP's gapped (non-prelim): 1150
length of query: 209
length of database: 18,247,518
effective HSP length: 98
effective length of query: 111
effective length of database: 14,536,650
effective search space: 1613568150
effective search space used: 1613568150
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.