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Search of human proteins with 7662470
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662470 neuroligin 1 [Homo sapiens]
(823 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662470 neuroligin 1 [Homo sapiens] 1713 0.0
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 1221 0.0
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 1221 0.0
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 1201 0.0
gi|51593088 neuroligin 3 [Homo sapiens] 1120 0.0
gi|30840978 neuroligin 2 [Homo sapiens] 1049 0.0
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 315 1e-85
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 314 2e-85
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 303 3e-82
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 286 7e-77
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 285 9e-77
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 284 2e-76
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 284 2e-76
gi|33563374 carboxylesterase 3 [Homo sapiens] 282 1e-75
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 278 1e-74
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 275 1e-73
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 266 4e-71
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 238 2e-62
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 229 8e-60
gi|55770862 thyroglobulin [Homo sapiens] 182 1e-45
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 142 2e-33
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 141 3e-33
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 93 9e-19
gi|68299767 arylacetamide deacetylase [Homo sapiens] 41 0.005
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 33 0.82
gi|23308699 transcription factor MAFB [Homo sapiens] 33 1.1
gi|83977459 pleckstrin homology-like domain, family A, member 1 ... 33 1.4
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 33 1.4
gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] 33 1.4
gi|4885509 neuroblastoma, suppression of tumorigenicity 1 2 prec... 32 1.8
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 1713 bits (4437), Expect = 0.0
Identities = 823/823 (100%), Positives = 823/823 (100%)
Query: 1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 60
MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG
Sbjct: 1 MALPRCTWPNYVWRAVMACLVHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFG 60
Query: 61 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 120
KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN
Sbjct: 61 KIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQN 120
Query: 121 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 180
IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH
Sbjct: 121 IIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIH 180
Query: 181 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 240
GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW
Sbjct: 181 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 240
Query: 241 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 300
TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL
Sbjct: 241 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 300
Query: 301 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 360
SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI
Sbjct: 301 SSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVI 360
Query: 361 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 420
DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD
Sbjct: 361 DGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVD 420
Query: 421 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 480
NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG
Sbjct: 421 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 480
Query: 481 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 540
SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM
Sbjct: 481 SPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVM 540
Query: 541 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 600
TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA
Sbjct: 541 TYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRA 600
Query: 601 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 660
NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ
Sbjct: 601 NKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRPTRKNSVPVTSAFPTAKQDDPKQ 660
Query: 661 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 720
QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN
Sbjct: 661 QPSPFSVDQRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQRTTTN 720
Query: 721 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 780
DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT
Sbjct: 721 DLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNT 780
Query: 781 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 823
ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV
Sbjct: 781 ITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 823
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1221 bits (3159), Expect = 0.0
Identities = 590/789 (74%), Positives = 662/789 (83%), Gaps = 36/789 (4%)
Query: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
P+V TN+GKIRG++ L NEILGPV Q+LGVPYA+PPTGERRFQPPEPPS W+ IRN TQ
Sbjct: 46 PVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQ 105
Query: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
FA VCPQ++ + L MLP+WFT NLD + +YVQDQ+EDCLYLNIYVPTEDDI D
Sbjct: 106 FAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSK 165
Query: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
KPVMVYIHGGSYMEGTGN+ DGS+LASYGNVIVIT+NYRLG+LGFLSTGDQAAKGNYGLL
Sbjct: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 225
Query: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
D IQALRW EN+G FGGDP R+T+FGSGAG SCV+LLTLSHYSEG LFQ+A
Sbjct: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEG---------LFQKA 276
Query: 293 IAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARY 352
I QSGTALSSWAV++QPAKY R+LA KVGCN+ DT ++VECL+ K YKEL+ Q I PA Y
Sbjct: 277 IIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATY 336
Query: 353 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFD 412
HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV+ IVD++DG++ +DFD
Sbjct: 337 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFD 396
Query: 413 FAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVAT 472
F+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD+ NPETRRKTL+ALFTDHQWVAPAVAT
Sbjct: 397 FSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVAT 456
Query: 473 ADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKND 532
ADLH+ +GSPTYFYAFYHHCQ++ P+WAD+AHGDEVPYV GIPMIGPTELF CNFSKND
Sbjct: 457 ADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKND 516
Query: 533 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKP 592
VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW++Y+ KDQLYLHIGLKP
Sbjct: 517 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP 576
Query: 593 RVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRP--TRKNSVPVTSAF 650
RV++HYRA KV WLELVPHLHNLN+I QY STTTKVP D+T P TR++ + +
Sbjct: 577 RVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKI---W 633
Query: 651 PTAKQ------DDPKQQPSPFSV----------DQRDYSTELSVTIAVGASLLFLNILAF 694
PT K+ ++PK P +RDYSTELSVTIAVGASLLFLNILAF
Sbjct: 634 PTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAF 693
Query: 695 AALYYKKDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVL 754
AALYYKKDKRRH+ HRR SPQR TTND+ H Q EEIMSLQMK + DHECES+ H+ L
Sbjct: 694 AALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHDHECESLQAHD-TL 752
Query: 755 RTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPH 814
R CPPDYTL +RRSPDD+PLMTPNTITMIPNT+ G+QPLHTFNTF+GGQN+T
Sbjct: 753 RLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQPLHTFNTFSGGQNST-----NL 807
Query: 815 PHSHSTTRV 823
PH HSTTRV
Sbjct: 808 PHGHSTTRV 816
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 1221 bits (3159), Expect = 0.0
Identities = 590/789 (74%), Positives = 662/789 (83%), Gaps = 36/789 (4%)
Query: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
P+V TN+GKIRG++ L NEILGPV Q+LGVPYA+PPTGERRFQPPEPPS W+ IRN TQ
Sbjct: 46 PVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQ 105
Query: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
FA VCPQ++ + L MLP+WFT NLD + +YVQDQ+EDCLYLNIYVPTEDDI D
Sbjct: 106 FAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTEDDIHDQNSK 165
Query: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
KPVMVYIHGGSYMEGTGN+ DGS+LASYGNVIVIT+NYRLG+LGFLSTGDQAAKGNYGLL
Sbjct: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLL 225
Query: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
D IQALRW EN+G FGGDP R+T+FGSGAG SCV+LLTLSHYSEG LFQ+A
Sbjct: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEG---------LFQKA 276
Query: 293 IAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARY 352
I QSGTALSSWAV++QPAKY R+LA KVGCN+ DT ++VECL+ K YKEL+ Q I PA Y
Sbjct: 277 IIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLRNKNYKELIQQTITPATY 336
Query: 353 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFD 412
HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV+ IVD++DG++ +DFD
Sbjct: 337 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFD 396
Query: 413 FAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVAT 472
F+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD+ NPETRRKTL+ALFTDHQWVAPAVAT
Sbjct: 397 FSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVAT 456
Query: 473 ADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKND 532
ADLH+ +GSPTYFYAFYHHCQ++ P+WAD+AHGDEVPYV GIPMIGPTELF CNFSKND
Sbjct: 457 ADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKND 516
Query: 533 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKP 592
VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW++Y+ KDQLYLHIGLKP
Sbjct: 517 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP 576
Query: 593 RVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRP--TRKNSVPVTSAF 650
RV++HYRA KV WLELVPHLHNLN+I QY STTTKVP D+T P TR++ + +
Sbjct: 577 RVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKI---W 633
Query: 651 PTAKQ------DDPKQQPSPFSV----------DQRDYSTELSVTIAVGASLLFLNILAF 694
PT K+ ++PK P +RDYSTELSVTIAVGASLLFLNILAF
Sbjct: 634 PTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAF 693
Query: 695 AALYYKKDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVL 754
AALYYKKDKRRH+ HRR SPQR TTND+ H Q EEIMSLQMK + DHECES+ H+ L
Sbjct: 694 AALYYKKDKRRHETHRRPSPQRNTTNDIAHIQNEEIMSLQMKQLEHDHECESLQAHD-TL 752
Query: 755 RTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPH 814
R CPPDYTL +RRSPDD+PLMTPNTITMIPNT+ G+QPLHTFNTF+GGQN+T
Sbjct: 753 RLTCPPDYTLTLRRSPDDIPLMTPNTITMIPNTLTGMQPLHTFNTFSGGQNST-----NL 807
Query: 815 PHSHSTTRV 823
PH HSTTRV
Sbjct: 808 PHGHSTTRV 816
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 1201 bits (3108), Expect = 0.0
Identities = 581/789 (73%), Positives = 658/789 (83%), Gaps = 36/789 (4%)
Query: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
P+V TN+GKI+G++ L +EILGPV Q+LGVPYA+PPTGERRFQPPE PS W+ IRNATQ
Sbjct: 46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQ 105
Query: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
F+ VCPQ++ + L MLP+WFT +LD + +YVQDQ+EDCLYLNIYVP EDDI +
Sbjct: 106 FSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSK 165
Query: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
KPVMVYIHGGSYMEGTGN+ DGS+LASYGNVIVIT+N RLG+LGFLSTGDQAAKGNYGLL
Sbjct: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLL 225
Query: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
D IQALRW EN+G FGGDP R+T+FGSGAG SCV+LLTLSHYSEG LFQ+A
Sbjct: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEG---------LFQKA 276
Query: 293 IAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARY 352
I QSGTALSSWAV++QPAKY R+LA KVGCN+ DT ++VECL+ K YKEL+ Q I PA Y
Sbjct: 277 IIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATY 336
Query: 353 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFD 412
HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFV+ IVD++DG++ +DFD
Sbjct: 337 HIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFD 396
Query: 413 FAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVAT 472
F+VSNFVDNLYGYPEGKD LRETIKFMYTDWAD+ NPETRRKTL+ALFTDHQWVAPAVAT
Sbjct: 397 FSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVAT 456
Query: 473 ADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKND 532
ADLH+ +GSPTYFYAFYHHCQ++ P+WAD+AHGDEVPYV GIPMIGPTELF CNFSKND
Sbjct: 457 ADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKND 516
Query: 533 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKP 592
VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW++Y+ KDQLYLHIGLKP
Sbjct: 517 VMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKP 576
Query: 593 RVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDITFRP--TRKNSVPVTSAF 650
RV++HYRA KV WLELVPHLHNLN+I QY STTTKVP D+T P TR++ + +
Sbjct: 577 RVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKI---W 633
Query: 651 PTAKQ------DDPKQQPSPFSV----------DQRDYSTELSVTIAVGASLLFLNILAF 694
PT K+ ++PK P +RDYSTELSVTIAVGASLLFLNILAF
Sbjct: 634 PTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAF 693
Query: 695 AALYYKKDKRRHDVHRRCSPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVL 754
AALYYKKDKRRH+ HR SPQR TTND+TH Q EEIMSLQMK + DHECES+ H+ L
Sbjct: 694 AALYYKKDKRRHETHRHPSPQRNTTNDITHIQNEEIMSLQMKQLEHDHECESLQAHD-TL 752
Query: 755 RTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPH 814
R CPPDYTL +RRSPDD+P MTPNTITMIPNT+ G+QPLHTF TF+GGQN+T
Sbjct: 753 RLTCPPDYTLTLRRSPDDIPFMTPNTITMIPNTLMGMQPLHTFKTFSGGQNST-----NL 807
Query: 815 PHSHSTTRV 823
PH HSTTRV
Sbjct: 808 PHGHSTTRV 816
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 1120 bits (2898), Expect = 0.0
Identities = 563/806 (69%), Positives = 641/806 (79%), Gaps = 54/806 (6%)
Query: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
P V T+FGK+RG + L +EILGPV Q+LGVPYAAPP GE+RF PPEPP WS IRNAT
Sbjct: 42 PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTED-------- 164
F PVCPQNI +PEVMLPVWFT NLD+V++Y+Q+ +EDCLYLN+YVPTED
Sbjct: 102 FPPVCPQNIHTA-VPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQG 160
Query: 165 ------------DIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRL 212
DIRDSG KPVMVYIHGGSYMEGTGN+ DGS+LASYGNVIVIT+NYR+
Sbjct: 161 EDLADNDGDEDEDIRDSGA-KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRV 219
Query: 213 GVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTL 272
GVLGFLSTGDQAAKGNYGLLD IQALRW SENI FFGGDP RITVFGSG G SCV+LLTL
Sbjct: 220 GVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTL 279
Query: 273 SHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVE 332
SH+SEG LFQRAI QSG+ALSSWAV++QP KY +LA KVGCNV DTV++V+
Sbjct: 280 SHHSEG---------LFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVD 330
Query: 333 CLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEG 392
CL++K KELV+QDIQPARYH+AFGPVIDGDVIPDDP+ILMEQGEFLNYDIMLGVNQGEG
Sbjct: 331 CLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGEG 390
Query: 393 LKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETR 452
LKFVE +VD +DG+S +DFD++VSNFVDNLYGYPEGKD LRETIKFMYTDWADR NPETR
Sbjct: 391 LKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADRDNPETR 450
Query: 453 RKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYV 512
RKTL+ALFTDHQWV P+V TADLH+ +GSPTYFYAFYHHCQ+ PAW+DAAHGDEVPYV
Sbjct: 451 RKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYV 510
Query: 513 LGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEE 572
G+PM+GPT+LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN+PVPQDTKFIHTK NRFEE
Sbjct: 511 FGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEE 570
Query: 573 VAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVP-- 630
VAW++Y+ +DQLYLHIGLKPRV++HYRA KV W LVPHL+NL+D+ YTSTTTKVP
Sbjct: 571 VAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPPP 630
Query: 631 ----STDITFRPTRKNSVPVTSAFPTAKQDD-------PKQQPSPFSVDQ-RDYSTELSV 678
S+ IT RP K A A ++ Q P V+ RDYSTELSV
Sbjct: 631 DTTHSSHITRRPNGKTWSTKRPAISPAYSNENAQGSWNGDQDAGPLLVENPRDYSTELSV 690
Query: 679 TIAVGASLLFLNILAFAALYYKKDKRRHDVHRRCSPQR-TTTNDLTHAQEEEIMSLQMKH 737
TIAVGASLLFLN+LAFAALYY+KDKRR + R+ SPQR +L A EEE+ +LQ+
Sbjct: 691 TIAVGASLLFLNVLAFAALYYRKDKRRQEPLRQPSPQRGAGAPELGAAPEEELAALQLGP 750
Query: 738 TDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGIQPLHTF 797
T HECE+ PH+ LR PDYTL +RRSPDD+PLMTPNTITMIPN++ G+Q LH +
Sbjct: 751 T--HHECEAGPPHD-TLRLTALPDYTLTLRRSPDDIPLMTPNTITMIPNSLVGLQTLHPY 807
Query: 798 NTFTGGQNNTLPHPHPHPHSHSTTRV 823
NTF G N+T PHSHSTTRV
Sbjct: 808 NTFAAGFNST-----GLPHSHSTTRV 828
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 1049 bits (2713), Expect = 0.0
Identities = 522/812 (64%), Positives = 617/812 (75%), Gaps = 59/812 (7%)
Query: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
P+V T +G++RG+++ELNNEILGPV+QFLGVPYA PP G RRFQPPE P+ W +RNAT
Sbjct: 42 PVVNTAYGRVRGVRRELNNEILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATT 101
Query: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTED-------- 164
P CPQN+ G LP +MLPVWFT+NL+ ++YVQ+QSEDCLYLN+YVPTED
Sbjct: 102 LPPACPQNL-HGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRD 160
Query: 165 ---------DIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVL 215
DIRD G KPVM+++HGGSYMEGTGN++DGSVLA+YGNVIV T+NYRLGVL
Sbjct: 161 EATLNPPDTDIRDPG-KKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVL 219
Query: 216 GFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHY 275
GFLSTGDQAAKGNYGLLD IQALRW SENI FGGDP RIT+FGSGAG SCVNLL LSH+
Sbjct: 220 GFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHH 279
Query: 276 SEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQ 335
SEG LFQ+AIAQSGTA+SSW+V++QP KY R+LA KVGC+ D+ E VECL+
Sbjct: 280 SEG---------LFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLR 330
Query: 336 KKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKF 395
+KP +ELVDQD+QPARYHIAFGPV+DGDV+PDDP+ILM+QGEFLNYD+++GVNQGEGLKF
Sbjct: 331 RKPSRELVDQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKF 390
Query: 396 VENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKT 455
VE+ +S+DG+SAS FDF VSNFVDNLYGYPEGKDVLRETIKFMYTDWADR N E RRKT
Sbjct: 391 VEDSAESEDGVSASAFDFTVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRDNGEMRRKT 450
Query: 456 LLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGI 515
LLALFTDHQWVAPAVATA LH+++ SP YFY FYHHCQ + P WADAAHGDE+PYV G+
Sbjct: 451 LLALFTDHQWVAPAVATAKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYVFGV 510
Query: 516 PMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAW 575
PM+G T+LFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEV W
Sbjct: 511 PMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVVW 570
Query: 576 TRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHLHNLNDISQYTSTTTKVPSTDIT 635
++++ K++ YLHIGLKPRV+++YRANKV WLELVPHLHNL+ ++ +TTT++P
Sbjct: 571 SKFNSKEKQYLHIGLKPRVRDNYRANKVAFWLELVPHLHNLH--TELFTTTTRLPPYATR 628
Query: 636 FRPTRKNSVPVTSAFPTAKQDDPKQQPSP-------FSVDQRDYSTELSVTIAVGASLLF 688
+ P P T P P+ +P P F D RDYSTELSVT+AVGASLLF
Sbjct: 629 WPPRPPAGAPGTRRPPPPATLPPEPEPEPGPRAYDRFPGDSRDYSTELSVTVAVGASLLF 688
Query: 689 LNILAFAALYYKKDKRRHDVHRRCSPQRTTTNDLTHA------------QEEEIMSLQMK 736
LNILAFAALYYK+D+R+ RR SP + + + EEE++SLQ+K
Sbjct: 689 LNILAFAALYYKRDRRQELRCRRLSPPGGSGSGVPGGGPLLPAAGRELPPEEELVSLQLK 748
Query: 737 HTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTI-----PGI 791
P E LR ACPPDYTLA+RR+PDDVPL+ P +T++P+ + P
Sbjct: 749 RGG----GVGADPAE-ALRPACPPDYTLALRRAPDDVPLLAPGALTLLPSGLGPPPPPPP 803
Query: 792 QPLHTFNTFTGGQNNTLPHPHPHPHSHSTTRV 823
LH F F H + PH HSTTRV
Sbjct: 804 PSLHPFGPFPPPPPTATSHNNTLPHPHSTTRV 835
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 315 bits (807), Expect = 1e-85
Identities = 214/635 (33%), Positives = 312/635 (49%), Gaps = 80/635 (12%)
Query: 19 CLVHR-GLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPV 77
CL+H L +PL L +L L G V ++ +D + LV G++RGI+ + GPV
Sbjct: 6 CLLHTPSLASPLLLLLLWLL--GGGVGAEGREDAELLVTVRGGRLRGIRLKTPG---GPV 60
Query: 78 IQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVM-LPVWFT 136
FLG+P+A PP G RRF PPEP PWS + +AT F VC Q +D P +W
Sbjct: 61 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQ-YVDTLYPGFEGTEMWNP 119
Query: 137 NNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNL--YDG 194
N ++ SEDCLYLN++ P P PV+V+I+GG + G +L YDG
Sbjct: 120 N---------RELSEDCLYLNVWTPYPRPT----SPTPVLVWIYGGGFYSGASSLDVYDG 166
Query: 195 SVLASYGNVIVITVNYRLGVLGFLS-TGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPL 253
L +++++NYR+G GFL+ G + A GN GLLD AL+W EN+ FGGDP
Sbjct: 167 RFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPT 226
Query: 254 RITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAV--SFQPAK 311
+T+FG AG + V + LS S +GLF RA+ QSG WA + +
Sbjct: 227 SVTLFGESAGAASVGMHLLSPPS---------RGLFHRAVLQSGAPNGPWATVGMGEARR 277
Query: 312 YARMLATKVGCNVSDT----VELVECLQKKPYKELVDQD----IQPARYHIAFGPVIDGD 363
A LA VGC T ELV CL+ +P + LV+ + Q + + +F PV+DGD
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337
Query: 364 VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVEN-----IVDSDDGISASDFDFAVSNF 418
+ D P+ L+ G+F +++GV + EG F+ D++ IS ++F V
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR-- 395
Query: 419 VDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSN 478
G P+ D+ E + YTDW +P R+ L + DH V P A +
Sbjct: 396 ----VGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAA 451
Query: 479 FGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAV 538
G+ Y Y F H T P W HG E+ ++ GIP + P+ N++ + + +
Sbjct: 452 QGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIP-LDPSR----NYTAEEKIFAQR 506
Query: 539 VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKP-RVKEH 597
+M YW NFA+TGDPN+ P+D K W Y+ Q Y+ + L+P V+
Sbjct: 507 LMRYWANFARTGDPNE--PRDPK----------APQWPPYTAGAQQYVSLDLRPLEVRRG 554
Query: 598 YRANKVNLWLELVPHLHNLNDISQYTSTTTKVPST 632
RA W +P L ++T ++ PST
Sbjct: 555 LRAQACAFWNRFLPKL--------LSATASEAPST 581
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 314 bits (805), Expect = 2e-85
Identities = 211/621 (33%), Positives = 306/621 (49%), Gaps = 72/621 (11%)
Query: 19 CLVHR-GLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPV 77
CL+H L +PL L +L L G V ++ +D + LV G++RGI+ + GPV
Sbjct: 6 CLLHTPSLASPLLLLLLWLL--GGGVGAEGREDAELLVTVRGGRLRGIRLKTPG---GPV 60
Query: 78 IQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVM-LPVWFT 136
FLG+P+A PP G RRF PPEP PWS + +AT F VC Q +D P +W
Sbjct: 61 SAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQ-YVDTLYPGFEGTEMWNP 119
Query: 137 NNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNL--YDG 194
N ++ SEDCLYLN++ P P PV+V+I+GG + G +L YDG
Sbjct: 120 N---------RELSEDCLYLNVWTPYPRPT----SPTPVLVWIYGGGFYSGASSLDVYDG 166
Query: 195 SVLASYGNVIVITVNYRLGVLGFLS-TGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPL 253
L +++++NYR+G GFL+ G + A GN GLLD AL+W EN+ FGGDP
Sbjct: 167 RFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPT 226
Query: 254 RITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAV--SFQPAK 311
+T+FG AG + V + LS S +GLF RA+ QSG WA + +
Sbjct: 227 SVTLFGESAGAASVGMHLLSPPS---------RGLFHRAVLQSGAPNGPWATVGMGEARR 277
Query: 312 YARMLATKVGCNVSDT----VELVECLQKKPYKELVDQD----IQPARYHIAFGPVIDGD 363
A LA VGC T ELV CL+ +P + LV+ + Q + + +F PV+DGD
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337
Query: 364 VIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVEN-----IVDSDDGISASDFDFAVSNF 418
+ D P+ L+ G+F +++GV + EG F+ D++ IS ++F V
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR-- 395
Query: 419 VDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSN 478
G P+ D+ E + YTDW +P R+ L + DH V P A +
Sbjct: 396 ----VGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAA 451
Query: 479 FGSPTYFYAFYHHCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAV 538
G+ Y Y F H T P W HG E+ ++ GIP + P+ N++ + + +
Sbjct: 452 QGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIP-LDPSR----NYTAEEKIFAQR 506
Query: 539 VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKP-RVKEH 597
+M YW NFA+TGDPN+ P+D K W Y+ Q Y+ + L+P V+
Sbjct: 507 LMRYWANFARTGDPNE--PRDPK----------APQWPPYTAGAQQYVSLDLRPLEVRRG 554
Query: 598 YRANKVNLWLELVPHLHNLND 618
RA W +P L + D
Sbjct: 555 LRAQACAFWNRFLPKLLSATD 575
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 303 bits (777), Expect = 3e-82
Identities = 200/602 (33%), Positives = 299/602 (49%), Gaps = 82/602 (13%)
Query: 29 LTLCMLGCLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAP 88
L LCML + + + D ++AT GK+RG+ + G V FLG+PYA P
Sbjct: 17 LLLCML---------IGKSHTEDDIIIATKNGKVRGMNLTVFG---GTVTAFLGIPYAQP 64
Query: 89 PTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQD 148
P G RF+ P+ + WSDI NAT++A C QNI D P + N D+
Sbjct: 65 PLGRLRFKKPQSLTKWSDIWNATKYANSCCQNI-DQSFPGFHGSEMWNPNTDL------- 116
Query: 149 QSEDCLYLNIYVPTEDDIRDSGGPKP----VMVYIHGGSYMEGTGNL--YDGSVLASYGN 202
SEDCLYLN+++P PKP V+++I+GG + GT +L YDG LA
Sbjct: 117 -SEDCLYLNVWIPA---------PKPKNATVLIWIYGGGFQTGTSSLHVYDGKFLARVER 166
Query: 203 VIVITVNYRLGVLGFLST-GDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSG 261
VIV+++NYR+G LGFL+ G+ A GN GL D AL+W +NI FGG+P +T+FG
Sbjct: 167 VIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGES 226
Query: 262 AGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVS--FQPAKYARMLATK 319
AG + V+L LS S LF RAI QSG+ + WAV+ ++ LA
Sbjct: 227 AGAASVSLHLLSPGSHS---------LFTRAILQSGSFNAPWAVTSLYEARNRTLNLAKL 277
Query: 320 VGCNVSDTVELVECLQKKPYKELVDQDIQPARY----HIAFGPVIDGDVIPDDPQILMEQ 375
GC+ + E+++CL+ K +E++ + Y + FGP +DGD + D P IL+E
Sbjct: 278 TGCSRENETEIIKCLRNKDPQEILLNEAFVVPYGTPLSVNFGPTVDGDFLTDMPDILLEL 337
Query: 376 GEFLNYDIMLGVNQGEGLKFVENIV-----DSDDGISASDFDFAVSNFVDNLYGYPEGKD 430
G+F I++GVN+ EG F+ D++ I+ +F + F +P +
Sbjct: 338 GQFKKTQILVGVNKDEGTAFLVYGAPGFSKDNNSIITRKEFQEGLKIF------FPGVSE 391
Query: 431 VLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYH 490
+E+I F YTDW D PE R+ L + D+ ++ PA+ S +G+ +FY F H
Sbjct: 392 FGKESILFHYTDWVDDQRPENYREALGDVVGDYNFICPALEFTKKFSEWGNNAFFYYFEH 451
Query: 491 HCQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTG 550
P W HG E+ +V G+P+ N++K + +LS ++ W NFAK G
Sbjct: 452 RSSKLPWPEWMGVMHGYEIEFVFGLPLERRD-----NYTKAEEILSRSIVKRWANFAKYG 506
Query: 551 DPNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLK-PRVKEHYRANKVNLWLEL 609
+PN+ T +W + +Q YL + + R+ RA + W
Sbjct: 507 NPNETQNNST-------------SWPVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWTSF 553
Query: 610 VP 611
P
Sbjct: 554 FP 555
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 286 bits (731), Expect = 7e-77
Identities = 191/572 (33%), Positives = 284/572 (49%), Gaps = 61/572 (10%)
Query: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
P+V T GK+ G L PV FLG+P+A PP G RF PP+P PWS ++NAT
Sbjct: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
Query: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
+ P+C Q+ G+L L FTN + + + SEDCLYLNIY P + ++
Sbjct: 83 YPPMCTQDPKAGQL----LSELFTNRKENIPLKL---SEDCLYLNIYTPADLTKKNR--- 132
Query: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
PVMV+IHGG M G + YDG LA++ NV+V+T+ YRLG+ GF STGD+ ++GN+G L
Sbjct: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
Query: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
D + ALRW +NI FGG+P +T+FG AGG V++L LS + K LF RA
Sbjct: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLA---------KNLFHRA 243
Query: 293 IAQSGTALSSWAVSFQPAK-YARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQ--- 348
I++SG AL+S V K A +A GC + + +V CL++K +EL++ ++
Sbjct: 244 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 303
Query: 349 --------PARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIV 400
P G VIDG ++ P+ L + F M+G+N+ E + ++
Sbjct: 304 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLM 363
Query: 401 DSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALF 460
D A+S + K+++ E + Y D + ++ L L
Sbjct: 364 SYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATE-KYLGGTD--DTVKKKDLFLDLI 420
Query: 461 TDHQWVAPAVATADLHSNFGSPTYFYAFYHH--CQTDQVPAWADAAHGDEVPYVLGIPMI 518
D + P+V A H + G+PTY Y F + +D P HGDE+ V G P +
Sbjct: 421 ADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFL 480
Query: 519 GPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWTR 577
S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 481 KE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPE 518
Query: 578 YSQKDQLYLHIGLKPRVKEHYRANKVNLWLEL 609
Y+QK+ YL IG + + + +V W L
Sbjct: 519 YNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 549
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 285 bits (730), Expect = 9e-77
Identities = 184/548 (33%), Positives = 283/548 (51%), Gaps = 52/548 (9%)
Query: 76 PVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWF 135
PV FLGVP+AAPP G RF P+P SPW ++R AT + +C QN L + ML V +
Sbjct: 53 PVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHY 112
Query: 136 TNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGS 195
SEDCLYLNIY P D+G PV+V+ GG++ G+ +++DGS
Sbjct: 113 PKF---------GVSEDCLYLNIYAPAH---ADTGSKLPVLVWFPGGAFKTGSASIFDGS 160
Query: 196 VLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRI 255
LA+Y +V+V+ V YRLG+ GF +T DQ A GN+ D + AL W +NI FFGGDP +
Sbjct: 161 ALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSV 220
Query: 256 TVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSW--AVSFQPAKYA 313
T+FG AG V+ L LS + KGLF +AI +SG A+ + A ++ ++
Sbjct: 221 TIFGESAGAISVSSLILSPMA---------KGLFHKAIMESGVAIIPYLEAHDYEKSEDL 271
Query: 314 RMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILM 373
+++A G N SD+ L+ CL+ KP KEL+ + +F V+DG P++P L+
Sbjct: 272 QVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK----SFTRVVDGAFFPNEPLDLL 327
Query: 374 EQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLR 433
Q F ++GVN E F+ + ++ + +S S+ A+ + L+ P+ ++
Sbjct: 328 SQKAFKAIPSIIGVNNHE-CGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVA 386
Query: 434 ETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYH--H 491
+ D+H+ R +LL L D +V PA+ TA H + G+P YFY F H
Sbjct: 387 NEY------FHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRDAGAPVYFYEFRHRPQ 440
Query: 492 CQTDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGD 551
C D PA+ A H DEV +V G + + ++ + +LS +M YW FA+TG+
Sbjct: 441 CFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFEGATEEEKLLSRKMMKYWATFARTGN 500
Query: 552 PNQPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP 611
PN + W Y+ +Q YL + L + + + +V+ W +P
Sbjct: 501 PNGN---------------DLSLWPAYNLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIP 544
Query: 612 HLHNLNDI 619
+ + +D+
Sbjct: 545 LILSASDM 552
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 284 bits (727), Expect = 2e-76
Identities = 192/573 (33%), Positives = 284/573 (49%), Gaps = 62/573 (10%)
Query: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
P+V T GK+ G L PV FLG+P+A PP G RF PP+P PWS ++NAT
Sbjct: 25 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 83
Query: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
+ P+C Q+ G+L L FTN + + + SEDCLYLNIY P + ++
Sbjct: 84 YPPMCTQDPKAGQL----LSELFTNRKENIPLKL---SEDCLYLNIYTPADLTKKNR--- 133
Query: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
PVMV+IHGG M G + YDG LA++ NV+V+T+ YRLG+ GF STGD+ ++GN+G L
Sbjct: 134 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 193
Query: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
D + ALRW +NI FGG+P +T+FG AGG V++L LS + K LF RA
Sbjct: 194 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLA---------KNLFHRA 244
Query: 293 IAQSGTALSSWAVSFQPAK-YARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQ--- 348
I++SG AL+S V K A +A GC + + +V CL++K +EL++ ++
Sbjct: 245 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 304
Query: 349 --------PARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE-GLKFVENI 399
P G VIDG ++ P+ L + F M+G+N+ E G +
Sbjct: 305 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQL 364
Query: 400 VDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLAL 459
+ D A+S + K+++ E + Y D + ++ L L
Sbjct: 365 MSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATE-KYLGGTD--DTVKKKDLFLDL 421
Query: 460 FTDHQWVAPAVATADLHSNFGSPTYFYAFYHH--CQTDQVPAWADAAHGDEVPYVLGIPM 517
D + P+V A H + G+PTY Y F + +D P HGDE+ V G P
Sbjct: 422 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 481
Query: 518 IGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWT 576
+ S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 482 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 519
Query: 577 RYSQKDQLYLHIGLKPRVKEHYRANKVNLWLEL 609
Y+QK+ YL IG + + + +V W L
Sbjct: 520 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 551
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 284 bits (727), Expect = 2e-76
Identities = 192/573 (33%), Positives = 284/573 (49%), Gaps = 62/573 (10%)
Query: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
P+V T GK+ G L PV FLG+P+A PP G RF PP+P PWS ++NAT
Sbjct: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
Query: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
+ P+C Q+ G+L L FTN + + + SEDCLYLNIY P + ++
Sbjct: 83 YPPMCTQDPKAGQL----LSELFTNRKENIPLKL---SEDCLYLNIYTPADLTKKNR--- 132
Query: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
PVMV+IHGG M G + YDG LA++ NV+V+T+ YRLG+ GF STGD+ ++GN+G L
Sbjct: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
Query: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
D + ALRW +NI FGG+P +T+FG AGG V++L LS + K LF RA
Sbjct: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLA---------KNLFHRA 243
Query: 293 IAQSGTALSSWAVSFQPAK-YARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQ--- 348
I++SG AL+S V K A +A GC + + +V CL++K +EL++ ++
Sbjct: 244 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 303
Query: 349 --------PARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE-GLKFVENI 399
P G VIDG ++ P+ L + F M+G+N+ E G +
Sbjct: 304 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQL 363
Query: 400 VDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLAL 459
+ D A+S + K+++ E + Y D + ++ L L
Sbjct: 364 MSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATE-KYLGGTD--DTVKKKDLFLDL 420
Query: 460 FTDHQWVAPAVATADLHSNFGSPTYFYAFYHH--CQTDQVPAWADAAHGDEVPYVLGIPM 517
D + P+V A H + G+PTY Y F + +D P HGDE+ V G P
Sbjct: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
Query: 518 IGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWT 576
+ S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 481 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 518
Query: 577 RYSQKDQLYLHIGLKPRVKEHYRANKVNLWLEL 609
Y+QK+ YL IG + + + +V W L
Sbjct: 519 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 282 bits (721), Expect = 1e-75
Identities = 194/587 (33%), Positives = 291/587 (49%), Gaps = 62/587 (10%)
Query: 36 CLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQ-FLGVPYAAPPTGERR 94
CLL A + + P V T G++RG +++ + ++ FLG+P+A PP G R
Sbjct: 17 CLLLACPATATGPEVAQPEVDTTLGRVRG--RQVGVKGTDRLVNVFLGIPFAQPPLGPDR 74
Query: 95 FQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCL 154
F P P PW +R+A+ P+C Q++ E M F N + SEDCL
Sbjct: 75 FSAPHPAQPWEGVRDASTAPPMCLQDV------ESMNSSRFVLN---GKQQIFSVSEDCL 125
Query: 155 YLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGV 214
LN+Y P E +G +PVMV++HGG+ + G YDGS LA+YG+V+V+TV YRLGV
Sbjct: 126 VLNVYSPAEVP---AGSGRPVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGV 182
Query: 215 LGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSH 274
LGF STGD+ A GN G LD++ ALRW ENI FGGD +TVFG AGGS ++ L LS
Sbjct: 183 LGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSP 242
Query: 275 YSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECL 334
+ GLF RAI QSG + + P A+ +A + C+ S E+V+CL
Sbjct: 243 VA---------AGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAEMVQCL 293
Query: 335 QKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLK 394
Q+K +ELV + + + +DG V P P+ L+++ F + ++GVN E
Sbjct: 294 QQKEGEELV---LSKKLKNTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSW 350
Query: 395 FVE---NIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPET 451
+ ++D+ + +S D A+S V DV E + + ++ ++
Sbjct: 351 LIPRGWGLLDTMEQMSREDM-LAISTPV------LTSLDVPPEMMPTVIDEYLGSNSDAQ 403
Query: 452 RRKTLLALFTDHQWV-APAVATADLHSNFGSPTYFYAFYHHCQT--DQVPAWADAAHGDE 508
+ F ++ P V+ + + GSP +FY F H + PAW A HG E
Sbjct: 404 AKCQAFQEFMGDVFINVPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAE 463
Query: 509 VPYVLGIPMI---GPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIH 564
+V G P + FP ++ + LS +M WT+FA+TGDPN + +P
Sbjct: 464 GAFVFGGPFLMDESSRLAFP-EATEEEKQLSLTMMAQWTHFARTGDPNSKALP------- 515
Query: 565 TKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP 611
W +++Q +Q YL I PR + +R + W E +P
Sbjct: 516 ---------PWPQFNQAEQ-YLEINPVPRAGQKFREAWMQFWSETLP 552
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 278 bits (711), Expect = 1e-74
Identities = 200/603 (33%), Positives = 293/603 (48%), Gaps = 74/603 (12%)
Query: 21 VHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQF 80
+HR L A L+ G LL V Q D P+ T+ G++ G + G V F
Sbjct: 67 LHR-LRARLSAVACGLLLLL--VRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTF 122
Query: 81 LGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLD 140
LG+P+A PP G RF PPEPP WS +R+ T +C Q+ L V N+
Sbjct: 123 LGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQD-----LTAVESEFLSQFNMT 177
Query: 141 VVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASY 200
S SEDCLYL+IY P G PVMV+IHGG+ + G +LYDGS+LA+
Sbjct: 178 FPSD---SMSEDCLYLSIYTPAHSH---EGSNLPVMVWIHGGALVFGMASLYDGSMLAAL 231
Query: 201 GNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGS 260
NV+V+ + YRLGVLGF STGD+ A GN+G LD + ALRW +NI FGG+P R+T+FG
Sbjct: 232 ENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGE 291
Query: 261 GAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKV 320
AGG+ V+ L +S S+ GLF AI +SG AL ++ + ++A
Sbjct: 292 SAGGTSVSSLVVSPISQ---------GLFHGAIMESGVALLPGLIASSADVISTVVANLS 342
Query: 321 GCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLN 380
C+ D+ LV CL+ K +E++ + +P + V+DG +P PQ L+ +F
Sbjct: 343 ACDQVDSEALVGCLRGKSKEEILAIN-KPFK---MIPGVVDGVFLPRHPQELLASADFQP 398
Query: 381 YDIMLGVNQGEG---LKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIK 437
++GVN E + V I D+ + A+ + L P D+LRE
Sbjct: 399 VPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY- 457
Query: 438 FMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQV 497
D +P+T + + D +V PA+ A + +P YFY F H
Sbjct: 458 -----IGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQ------ 505
Query: 498 PAW--------ADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKT 549
P+W A HGDE+P+V G + F++ + LS +M YW NFA+
Sbjct: 506 PSWLKNIRPPHMKADHGDELPFVFR-SFFGGNYI---KFTEEEEQLSRKMMKYWANFARN 561
Query: 550 GDPN-QPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLE 608
G+PN + +P W + Q++Q YL + L+P V +A+++ W +
Sbjct: 562 GNPNGEGLPH----------------WPLFDQEEQ-YLQLNLQPAVGRALKAHRLQFWKK 604
Query: 609 LVP 611
+P
Sbjct: 605 ALP 607
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 275 bits (704), Expect = 1e-73
Identities = 197/580 (33%), Positives = 272/580 (46%), Gaps = 91/580 (15%)
Query: 55 VATNFGKIRGIKKELNNEILGPVIQ-FLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQF 113
V T G + G+ K+L +LG + F G+P+AAP + + P+P W A F
Sbjct: 29 VYTEGGFVEGVNKKLG--LLGDSVDIFKGIPFAAPT---KALENPQPHPGWQGTLKAKNF 83
Query: 114 APVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQS---EDCLYLNIYVPTEDDIRDSG 170
C Q I QD + EDCLYLNI+VP +
Sbjct: 84 KKRCLQATI-----------------------TQDSTYGDEDCLYLNIWVP--QGRKQVS 118
Query: 171 GPKPVMVYIHGGSYMEGTGN--------LYDGSVLASYGNVIVITVNYRLGVLGFLSTGD 222
PVM++I+GG+++ G+G+ LYDG +A+ GNVIV+T NYR+G LGFLSTGD
Sbjct: 119 RDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYRVGPLGFLSTGD 178
Query: 223 QAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWS 282
GNYGL D A+ W NI FGGDP IT+FG AGG+ V+L TLS Y+
Sbjct: 179 ANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLSPYN------ 232
Query: 283 NSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQ------- 335
KGL +RAI+QSG ALS W + P +A+ +A KVGC V D + +CL+
Sbjct: 233 ---KGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGDAARMAQCLKVTDPRAL 289
Query: 336 KKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKF 395
YK + P +++ F PVIDGD IP DP L ++Y + G N +G F
Sbjct: 290 TLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADIDY--IAGTNNMDGHIF 347
Query: 396 ----VENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPET 451
+ I + ++ DF VS F +G + T WA + E
Sbjct: 348 ASIDMPAINKGNKKVTEEDFYKLVSEFT-----ITKGLRGAKTTFDVYTESWAQDPSQEN 402
Query: 452 RRKTLLALFTDHQWVAPA-VATADLHSNFGS-PTYFYAFYHHCQTDQVPAWADAAHGDEV 509
++KT++ TD ++ P +A A +N S TY Y F H + P W A H D++
Sbjct: 403 KKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDI 462
Query: 510 PYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNR 569
YV G P PT + D +S ++ YWTNFAKTGDPN +
Sbjct: 463 QYVFGKPFATPT-----GYRPQDRTVSKAMIAYWTNFAKTGDPNM------------GDS 505
Query: 570 FEEVAWTRYSQKDQLYLHIGLK---PRVKEHYRANKVNLW 606
W Y+ ++ YL I K +K R N + W
Sbjct: 506 AVPTHWEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYW 545
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 266 bits (681), Expect = 4e-71
Identities = 194/597 (32%), Positives = 286/597 (47%), Gaps = 78/597 (13%)
Query: 21 VHRGLGAPLTLCMLGCLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQF 80
+HR L A L+ G LL V Q D P+ T+ G++ G + G V F
Sbjct: 67 LHR-LRARLSAVACGLLLLL--VRGQGQDSASPIRTTHTGQVLGSLVHVKGANAG-VQTF 122
Query: 81 LGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLD 140
LG+P+A PP G RF PPEPP WS +R+ T +C Q+ L V N+
Sbjct: 123 LGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQD-----LTAVESEFLSQFNMT 177
Query: 141 VVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASY 200
S SEDCLYL+IY P G PVMV+IHGG+ + G +LYDGS+LA+
Sbjct: 178 FPSD---SMSEDCLYLSIYTPAHSH---EGSNLPVMVWIHGGALVFGMASLYDGSMLAAL 231
Query: 201 GNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGS 260
NV+V+ + YRLGVLGF STGD+ A GN+G LD + ALRW +NI FGG+P R+T+FG
Sbjct: 232 ENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGE 291
Query: 261 GAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATKV 320
AGG+ V+ L +S S+ GLF AI +SG AL ++ + ++A
Sbjct: 292 SAGGTSVSSLVVSPISQ---------GLFHGAIMESGVALLPGLIASSADVISTVVANLS 342
Query: 321 GCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLN 380
C+ D+ LV CL+ K +E++ + +P + V+DG +P PQ L+ +F
Sbjct: 343 ACDQVDSEALVGCLRGKSKEEILAIN-KPFK---MIPGVVDGVFLPRHPQELLASADFQP 398
Query: 381 YDIMLGVNQGEG---LKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIK 437
++GVN E + V I D+ + A+ + L P D+LRE
Sbjct: 399 VPSIVGVNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEY- 457
Query: 438 FMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQTDQV 497
D +P+T + + D +V PA+ A + +P YFY F H
Sbjct: 458 -----IGDNGDPQTLQAQFQEMMADSMFVIPALQVAHFQCS-RAPVYFYEFQHQ------ 505
Query: 498 PAWADAAHGDEVPYVLGIPMIGPTELFP--CNFSKNDVMLSAVVMTYWTNFAKTGDPN-Q 554
P+W + I P + F++ + LS +M YW NFA+ G+PN +
Sbjct: 506 PSW--------------LKNIRPPHMKADHVKFTEEEEQLSRKMMKYWANFARNGNPNGE 551
Query: 555 PVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVP 611
+P W + Q++Q YL + L+P V +A+++ W + +P
Sbjct: 552 GLPH----------------WPLFDQEEQ-YLQLNLQPAVGRALKAHRLQFWKKALP 591
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 238 bits (607), Expect = 2e-62
Identities = 169/546 (30%), Positives = 260/546 (47%), Gaps = 98/546 (17%)
Query: 76 PVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWF 135
PV FLGVP+AAPP G RF P+P SPW ++R AT + +C QN L + ML V +
Sbjct: 53 PVNVFLGVPFAAPPLGSLRFTNPQPASPWDNLREATSYPNLCLQNSEWLLLDQHMLKVHY 112
Query: 136 TNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGS 195
SEDCLYLNIY P D+G PV+V+ GG++ G+ +++DGS
Sbjct: 113 PKF---------GVSEDCLYLNIYAPAH---ADTGSKLPVLVWFPGGAFKTGSASIFDGS 160
Query: 196 VLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRI 255
LA+Y +V+V+ V YRLG+ GF +T DQ A GN+ D + AL W +NI FFGGDP +
Sbjct: 161 ALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSV 220
Query: 256 TVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSW--AVSFQPAKYA 313
T+FG AG V+ L LS + KGLF +AI +SG A+ + A ++ ++
Sbjct: 221 TIFGESAGAISVSSLILSPMA---------KGLFHKAIMESGVAIIPYLEAHDYEKSEDL 271
Query: 314 RMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGPVIDGDVIPDDPQILM 373
+++A G N SD+ L+ CL+ KP KEL+ + +F V+DG P++P L+
Sbjct: 272 QVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTK----SFTRVVDGAFFPNEPLDLL 327
Query: 374 EQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLR 433
Q F ++GVN E F+ + ++ + +S S+ A+ + L+ P+ ++
Sbjct: 328 SQKAFKAIPSIIGVNNHE-CGFLLPMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVA 386
Query: 434 ETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAFYHHCQ 493
+ D+H+ R +LL L D +V PA+ TA H
Sbjct: 387 NEY------FHDKHSLTEIRDSLLDLLGDVFFVVPALITARYHRE--------------- 425
Query: 494 TDQVPAWADAAHGDEVPYVLGIPMIGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN 553
G TE + +LS +M YW FA+TG+PN
Sbjct: 426 -------------------------GATE--------EEKLLSRKMMKYWATFARTGNPN 452
Query: 554 QPVPQDTKFIHTKPNRFEEVAWTRYSQKDQLYLHIGLKPRVKEHYRANKVNLWLELVPHL 613
+ W Y+ +Q YL + L + + + +V+ W +P +
Sbjct: 453 GN---------------DLSLWPAYNLTEQ-YLQLDLNMSLGQRLKEPRVDFWTSTIPLI 496
Query: 614 HNLNDI 619
+ +D+
Sbjct: 497 LSASDM 502
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 229 bits (584), Expect = 8e-60
Identities = 146/384 (38%), Positives = 200/384 (52%), Gaps = 60/384 (15%)
Query: 29 LTLCMLGCLLQAGHVLSQKLDDVDPLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAP 88
LTLC++ L P V T +G ++G + + P+ FLGVP++ P
Sbjct: 9 LTLCLMA------QTALGALHTKRPQVVTKYGTLQGKQMHVGKT---PIQVFLGVPFSRP 59
Query: 89 PTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQD 148
P G RF PPEPP PW IR+AT + P C Q W + S YV
Sbjct: 60 PLGILRFAPPEPPEPWKGIRDATTYPPGCLQES------------WG----QLASMYVST 103
Query: 149 Q--------SEDCLYLNIYVPTEDDIRDSGGPK-PVMVYIHGGSYMEGTGNLYDGSVLAS 199
+ SEDCLYLN+Y P R G P+ PVMV+ GG+++ G + Y+GS LA+
Sbjct: 104 RERYKWLRFSEDCLYLNVYAPA----RAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAA 159
Query: 200 YGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFG 259
V+++ + +RLG+ GFLST D A+GN+GLLD + ALRW ENI FGGDP +T+FG
Sbjct: 160 REKVVLVFLQHRLGIFGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFG 219
Query: 260 SGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKYARMLATK 319
AG ++ L +S + GLF RAI+QSGTAL ++ P K A+ +A
Sbjct: 220 QSAGAMSISGLMMSPLA---------SGLFHRAISQSGTALFRLFITSNPLKVAKKVAHL 270
Query: 320 VGCNVSDTVELVECLQ------------KKPYKELVDQDIQPARYHIAFGPVIDGDVIPD 367
GCN + T LV CL+ K + +L Q P + PV+DG VIPD
Sbjct: 271 AGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQR-DPEEIIWSMSPVVDGVVIPD 329
Query: 368 DPQILMEQGEFLNYDIMLGVNQGE 391
DP +L+ QG+ + +LGVN E
Sbjct: 330 DPLVLLTQGKVSSVPYLLGVNNLE 353
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 182 bits (462), Expect = 1e-45
Identities = 155/500 (31%), Positives = 239/500 (47%), Gaps = 74/500 (14%)
Query: 77 VIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQFAPVCPQNIIDGRLPEVMLPVWFT 136
V QFLGVPYAAPP ERRFQ PEP + W+ +A++ C W
Sbjct: 2225 VDQFLGVPYAAPPLAERRFQAPEPLN-WTGSWDASKPRASC----------------WQP 2267
Query: 137 NNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGN--LYDG 194
S V SEDCLYLN+++P ++ V+V+ H E + DG
Sbjct: 2268 GTRTSTSPGV---SEDCLYLNVFIP-----QNVAPNASVLVFFHNTMDREESEGWPAIDG 2319
Query: 195 SVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIGFFGGDPLR 254
S LA+ GN+IV+T +YR+GV GFLS+G GN+GLLD + AL W +I FGGDP R
Sbjct: 2320 SFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRR 2379
Query: 255 ITVFG--SGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAV-SFQPA- 310
+++ GA + ++LLT R +NS LF+RA+ G+ALS AV S + A
Sbjct: 2380 VSLAADRGGADVASIHLLTA-------RATNSQ--LFRRAVLMGGSALSPAAVISHERAQ 2430
Query: 311 KYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQ------PARYHIAFGPVIDGDV 364
+ A LA +V C +S + E+V CL++KP L D + P Y +GPVIDG
Sbjct: 2431 QQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFHY---WGPVIDGHF 2487
Query: 365 IPDDPQILMEQGEFLNYDIMLGVNQGEGL----KFVENIVDSDDGISASDFDFAVSNFVD 420
+ + P +++ ++ D+++G +Q +GL K V+ +S S+ A +
Sbjct: 2488 LREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRTSSKT---AFYQALQ 2544
Query: 421 NLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFG 480
N G + + + Y+ + + + L D+ + P + D+ S +
Sbjct: 2545 NSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPII---DMASAWA 2601
Query: 481 SPTYFYAFYHHCQTDQVPAWADAAHGD-----EVPYVLGIPMIGPTELFPCNFSKNDVML 535
F +H A + HG +V + LG+P + FS + L
Sbjct: 2602 KRARGNVFMYH-------APENYGHGSLELLADVQFALGLPFY---PAYEGQFSLEEKSL 2651
Query: 536 SAVVMTYWTNFAKTGDPNQP 555
S +M Y+++F ++G+PN P
Sbjct: 2652 SLKIMQYFSHFIRSGNPNYP 2671
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 142 bits (357), Expect = 2e-33
Identities = 95/298 (31%), Positives = 155/298 (52%), Gaps = 22/298 (7%)
Query: 181 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 240
GG++ G+ +++DGS LA+Y +++V+ V YRLG+ GF +T DQ A GN+ D + AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 241 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 300
+NI FFGGDP +T+FG G V+ L LS +E GLF +A+ +SG A+
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAE---------GLFHKAVMESGVAI 130
Query: 301 SSW--AVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGP 358
+ A ++ ++ +++A G N SD+ + CL+ K KEL+ + AF
Sbjct: 131 ILYLKAHDYEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK----AFTQ 186
Query: 359 VIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNF 418
V+DG P++P L+ Q F ++GVN E F + ++ + +S S+ A+
Sbjct: 187 VVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPE-CGFPLPMKEAPEILSGSNKSLALCLT 245
Query: 419 VDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLH 476
+ L+ P ++ + D+H+ R +LL L D +V P + TA H
Sbjct: 246 QNILHILPNYLHLVAGEY------FHDKHSLTEIRDSLLDLLGDVFFVIPKLITAQYH 297
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 141 bits (355), Expect = 3e-33
Identities = 95/298 (31%), Positives = 155/298 (52%), Gaps = 22/298 (7%)
Query: 181 GGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRW 240
GG++ G+ +++DGS LA+Y +++V+ V YRLG+ GF +T DQ A GN+ D + AL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 241 TSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTAL 300
+NI FFGGDP +T+FG G V+ L LS +E GLF +A+ +SG A+
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAE---------GLFHKAVMESGVAI 130
Query: 301 SSW--AVSFQPAKYARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQPARYHIAFGP 358
+ A ++ ++ +++A G N SD+ + CL+ K KEL+ + AF
Sbjct: 131 ILYLKAHDYEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTK----AFTQ 186
Query: 359 VIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNF 418
V+DG P++P L+ Q F ++GVN E F + ++ + +S S+ A+
Sbjct: 187 VVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPE-CGFPLPMKEAPEILSGSNKSLALCLT 245
Query: 419 VDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLH 476
+ L+ P ++ + D+H+ R +LL L D +V P + TA H
Sbjct: 246 QNILHILPNYLHLVAGEY------FHDKHSLTEIRDSLLDLLGDVFFVIPKLITARYH 297
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 93.2 bits (230), Expect = 9e-19
Identities = 40/93 (43%), Positives = 63/93 (67%)
Query: 172 PKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGL 231
P V+++ GG++ G+ +++DGS LA+Y +++V+ V YRLG+ GF +T DQ A GN+
Sbjct: 17 PPRVLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAF 76
Query: 232 LDLIQALRWTSENIGFFGGDPLRITVFGSGAGG 264
D + AL W +NI FFGGDP +T+F + + G
Sbjct: 77 KDQVAALSWVQKNIEFFGGDPSSVTIFDAVSHG 109
>gi|68299767 arylacetamide deacetylase [Homo sapiens]
Length = 399
Score = 40.8 bits (94), Expect = 0.005
Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 23/126 (18%)
Query: 154 LYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYG----NVIVITVN 209
+ + +YVP R S + + YIHGG + G+ L +L+ + + +V++ N
Sbjct: 89 ILVRVYVPK----RKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTN 144
Query: 210 YRLGVLGFLSTGDQAAKGNYGLL--DLIQALRW--TSENIGFFGGDPLRITVFGSGAGGS 265
YRL A K ++ + D+ ALRW + + +G +P RI + G AGG+
Sbjct: 145 YRL-----------APKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGN 193
Query: 266 CVNLLT 271
+T
Sbjct: 194 LAAAVT 199
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 33.5 bits (75), Expect = 0.82
Identities = 35/112 (31%), Positives = 41/112 (36%), Gaps = 13/112 (11%)
Query: 713 SPQRTTTNDLTHAQEEEIMSLQMKHTDLDHECESIHPHEVVLRTACPPDYTLAMRRSPDD 772
SP TTT D T A + + T H + HP T P T+ D
Sbjct: 1148 SPHPTTTPDPTMAPDP---ITTLNPTVTPHFPTTPHP------TTTPHPTTITHSTMIPD 1198
Query: 773 VPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPH---PHPHPHSHSTT 821
P TP T I ++ P T FT Q T PH PHP H TT
Sbjct: 1199 -PTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTT 1249
Score = 32.0 bits (71), Expect = 2.4
Identities = 23/82 (28%), Positives = 30/82 (36%), Gaps = 10/82 (12%)
Query: 749 PHEVVLRTACPPDYTLAMRRSPDDVPLMTPNTITMIPNTIPGI----------QPLHTFN 798
P + + PD T + P TP++ T P T P P T
Sbjct: 1205 PFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQ 1264
Query: 799 TFTGGQNNTLPHPHPHPHSHST 820
FT Q T+PHP PH +T
Sbjct: 1265 PFTTMQPTTMPHPTTTPHPTTT 1286
>gi|23308699 transcription factor MAFB [Homo sapiens]
Length = 323
Score = 33.1 bits (74), Expect = 1.1
Identities = 15/48 (31%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Query: 769 SPDDVPLMTPNTITMIPNTIPGIQPLHTFNTFTGGQNNTLPHPHPHPH 816
+P+ + L + + + + P QPL +F++F G ++ H HPHPH
Sbjct: 96 NPEALNLTPEDAVEALIGSHPVPQPLQSFDSFRGAHHHH-HHHHPHPH 142
>gi|83977459 pleckstrin homology-like domain, family A, member 1
[Homo sapiens]
Length = 401
Score = 32.7 bits (73), Expect = 1.4
Identities = 11/15 (73%), Positives = 12/15 (80%)
Query: 804 QNNTLPHPHPHPHSH 818
Q + PHPHPHPHSH
Sbjct: 347 QLHPYPHPHPHPHSH 361
Score = 31.2 bits (69), Expect = 4.1
Identities = 14/37 (37%), Positives = 18/37 (48%), Gaps = 3/37 (8%)
Query: 785 PNTIPGIQPLHTF---NTFTGGQNNTLPHPHPHPHSH 818
P P Q LH + + ++ PHPHPHPH H
Sbjct: 339 PQPKPQPQQLHPYPHPHPHPHSHPHSHPHPHPHPHPH 375
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 32.7 bits (73), Expect = 1.4
Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 15/125 (12%)
Query: 375 QGEFLNYDIMLGVNQGEGLKFVENIVDSDDGISASDFDFAVSNFVDN---LYGYPEGKDV 431
+G+ L+ D +Q E +EN++ D F++S +D L YP K V
Sbjct: 1059 RGKDLDTDFTNNASQPETKAIIENLIQKQD--------FSLSVALDGGSMLVTYPYDKPV 1110
Query: 432 L----RETIKFMYTDWADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYA 487
+ET+K + + +A+ H + +D + A+ HS+ GS +
Sbjct: 1111 QTVENKETLKHLASLYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSV 1170
Query: 488 FYHHC 492
Y HC
Sbjct: 1171 TYGHC 1175
>gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]
Length = 401
Score = 32.7 bits (73), Expect = 1.4
Identities = 40/174 (22%), Positives = 70/174 (40%), Gaps = 22/174 (12%)
Query: 107 IRNATQFAPVCPQNIIDGRLPEVMLPVW---FTNNLDVVSSYVQDQSEDCLYLNIYVPTE 163
I F +C +N+ R E + ++ +T L V D + + + +Y+P
Sbjct: 39 IAKTCTFTAMCFENMRIMRYEEFISMIFRLDYTQPLSDEYITVTDTTFVDIPVRLYLPK- 97
Query: 164 DDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVL----ASYGNVIVITVNYRLGVLGFLS 219
R S + ++Y HGG + G+ L A+ + +V+ V+YRL
Sbjct: 98 ---RKSETRRRAVIYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFP 154
Query: 220 TG--DQAAKGNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLT 271
D A + LL+ I + +G DP RI + G +GG+ +T
Sbjct: 155 AQFEDGLAAVKFFLLEKI---------LTKYGVDPTRICIAGDSSGGNLATAVT 199
>gi|4885509 neuroblastoma, suppression of tumorigenicity 1 2
precursor [Homo sapiens]
Length = 180
Score = 32.3 bits (72), Expect = 1.8
Identities = 12/20 (60%), Positives = 12/20 (60%)
Query: 802 GGQNNTLPHPHPHPHSHSTT 821
G Q T PHPHPHPH T
Sbjct: 142 GSQPGTHPHPHPHPHPGGQT 161
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,281,213
Number of Sequences: 37866
Number of extensions: 1738580
Number of successful extensions: 5037
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 4816
Number of HSP's gapped (non-prelim): 75
length of query: 823
length of database: 18,247,518
effective HSP length: 111
effective length of query: 712
effective length of database: 14,044,392
effective search space: 9999607104
effective search space used: 9999607104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.