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Search of human proteins with 7662058
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7662058 tectonin beta-propeller repeat containing 2 [Homo
sapiens]
(1411 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7662058 tectonin beta-propeller repeat containing 2 [Homo sap... 2872 0.0
gi|31657123 Hermansky-Pudlak syndrome 5 isoform a [Homo sapiens] 106 1e-22
gi|31657125 Hermansky-Pudlak syndrome 5 isoform b [Homo sapiens] 88 5e-17
gi|31657127 Hermansky-Pudlak syndrome 5 isoform b [Homo sapiens] 88 5e-17
gi|32698704 tectonin beta-propeller repeat containing 1 [Homo sa... 70 1e-11
gi|16757970 niban protein isoform 2 [Homo sapiens] 47 1e-04
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 39 0.035
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 38 0.060
gi|157388929 epsin 3 [Homo sapiens] 37 0.10
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 37 0.13
gi|199559532 Abelson helper integration site 1 isoform b [Homo s... 36 0.30
gi|199559490 Abelson helper integration site 1 isoform a [Homo s... 36 0.30
gi|199559438 Abelson helper integration site 1 isoform a [Homo s... 36 0.30
gi|31542701 Abelson helper integration site 1 isoform a [Homo sa... 36 0.30
gi|31652242 transcription factor 20 isoform 2 [Homo sapiens] 36 0.30
gi|31652244 transcription factor 20 isoform 1 [Homo sapiens] 36 0.30
gi|4557515 damage-specific DNA binding protein 2 [Homo sapiens] 35 0.39
gi|45827755 transforming, acidic coiled-coil containing protein ... 35 0.39
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens] 35 0.67
gi|41281447 intraflagellar transport 140 [Homo sapiens] 35 0.67
gi|82830424 gon-4-like isoform a [Homo sapiens] 34 0.87
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens] 34 0.87
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens] 34 0.87
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 34 1.1
gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [H... 34 1.1
gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [H... 34 1.1
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 34 1.1
gi|149944410 hypothetical protein LOC57587 [Homo sapiens] 34 1.1
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 33 1.5
gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 ... 33 1.5
>gi|7662058 tectonin beta-propeller repeat containing 2 [Homo sapiens]
Length = 1411
Score = 2872 bits (7444), Expect = 0.0
Identities = 1411/1411 (100%), Positives = 1411/1411 (100%)
Query: 1 MASISEPVTFREFCPLYYLLNAIPTKIQKGFRSIVVYLTALDTNGDYIAVGSSIGMLYLY 60
MASISEPVTFREFCPLYYLLNAIPTKIQKGFRSIVVYLTALDTNGDYIAVGSSIGMLYLY
Sbjct: 1 MASISEPVTFREFCPLYYLLNAIPTKIQKGFRSIVVYLTALDTNGDYIAVGSSIGMLYLY 60
Query: 61 CRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLPGRNKQLRRF 120
CRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLPGRNKQLRRF
Sbjct: 61 CRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLPGRNKQLRRF 120
Query: 121 DVTGIHKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNSQLVLEEPSSIVQLDY 180
DVTGIHKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNSQLVLEEPSSIVQLDY
Sbjct: 121 DVTGIHKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNSQLVLEEPSSIVQLDY 180
Query: 181 SQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLTLYASRPGL 240
SQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLTLYASRPGL
Sbjct: 181 SQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLTLYASRPGL 240
Query: 241 RLWKADVHGTVQATFILKDAFAGGVKPFELHPRLESPNSGSCSLPERHLGLVSCFFQEGW 300
RLWKADVHGTVQATFILKDAFAGGVKPFELHPRLESPNSGSCSLPERHLGLVSCFFQEGW
Sbjct: 241 RLWKADVHGTVQATFILKDAFAGGVKPFELHPRLESPNSGSCSLPERHLGLVSCFFQEGW 300
Query: 301 VLSWNEYSIYLLDTVNQATIAGLEGSGDIVSVSCTENEIFFLKGDRNIIRISSRPEGLTS 360
VLSWNEYSIYLLDTVNQATIAGLEGSGDIVSVSCTENEIFFLKGDRNIIRISSRPEGLTS
Sbjct: 301 VLSWNEYSIYLLDTVNQATIAGLEGSGDIVSVSCTENEIFFLKGDRNIIRISSRPEGLTS 360
Query: 361 TVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGS 420
TVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGS
Sbjct: 361 TVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGS 420
Query: 421 GLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTC 480
GLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTC
Sbjct: 421 GLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTC 480
Query: 481 HSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQE 540
HSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQE
Sbjct: 481 HSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQE 540
Query: 541 NTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAREDVGGSDVTGLGDE 600
NTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAREDVGGSDVTGLGDE
Sbjct: 541 NTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAREDVGGSDVTGLGDE 600
Query: 601 PCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSA 660
PCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSA
Sbjct: 601 PCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSA 660
Query: 661 EQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGS 720
EQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGS
Sbjct: 661 EQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGS 720
Query: 721 VGGQLTPVSALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQ 780
VGGQLTPVSALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQ
Sbjct: 721 VGGQLTPVSALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQ 780
Query: 781 QDLSRLGAEDAGLLKPDQFAESWMGYSGPGYGILSLVVSEKYIWCLDYKGGLFCSALPGA 840
QDLSRLGAEDAGLLKPDQFAESWMGYSGPGYGILSLVVSEKYIWCLDYKGGLFCSALPGA
Sbjct: 781 QDLSRLGAEDAGLLKPDQFAESWMGYSGPGYGILSLVVSEKYIWCLDYKGGLFCSALPGA 840
Query: 841 GLRWQKFEDAVQQVAVSPSGALLWKIEQKSNRAFACGKVTIKGKRHWYEALPQAVFVALS 900
GLRWQKFEDAVQQVAVSPSGALLWKIEQKSNRAFACGKVTIKGKRHWYEALPQAVFVALS
Sbjct: 841 GLRWQKFEDAVQQVAVSPSGALLWKIEQKSNRAFACGKVTIKGKRHWYEALPQAVFVALS 900
Query: 901 DDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYRE 960
DDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYRE
Sbjct: 901 DDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYRE 960
Query: 961 GVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDD 1020
GVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDD
Sbjct: 961 GVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDD 1020
Query: 1021 DHWWQVSITDYVVFDQCSLFQTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSL 1080
DHWWQVSITDYVVFDQCSLFQTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSL
Sbjct: 1021 DHWWQVSITDYVVFDQCSLFQTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSL 1080
Query: 1081 LGVNNSGVWISSGKNEFHVAKGSLIGTYWNHVVPRGTASATKWAFVLASAAPTKEGSFLW 1140
LGVNNSGVWISSGKNEFHVAKGSLIGTYWNHVVPRGTASATKWAFVLASAAPTKEGSFLW
Sbjct: 1081 LGVNNSGVWISSGKNEFHVAKGSLIGTYWNHVVPRGTASATKWAFVLASAAPTKEGSFLW 1140
Query: 1141 LCQSSKDLCSVSAQSAQSRPSTVQLPPEAEMRAYAACQDALWALDSLGQVFIRTLSKSCP 1200
LCQSSKDLCSVSAQSAQSRPSTVQLPPEAEMRAYAACQDALWALDSLGQVFIRTLSKSCP
Sbjct: 1141 LCQSSKDLCSVSAQSAQSRPSTVQLPPEAEMRAYAACQDALWALDSLGQVFIRTLSKSCP 1200
Query: 1201 TGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEP 1260
TGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEP
Sbjct: 1201 TGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEP 1260
Query: 1261 PVQPAGVSLVSVHSSPNDQMLWVLDSRWNVHVRTGITEEMPVGTAWEHVPGLQACQLALS 1320
PVQPAGVSLVSVHSSPNDQMLWVLDSRWNVHVRTGITEEMPVGTAWEHVPGLQACQLALS
Sbjct: 1261 PVQPAGVSLVSVHSSPNDQMLWVLDSRWNVHVRTGITEEMPVGTAWEHVPGLQACQLALS 1320
Query: 1321 TRTVWARCPNGDLARRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVGPPGYLLQRL 1380
TRTVWARCPNGDLARRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVGPPGYLLQRL
Sbjct: 1321 TRTVWARCPNGDLARRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVGPPGYLLQRL 1380
Query: 1381 TKTFSHSHGTQKSSQAAMPHPEDLEDEWEVI 1411
TKTFSHSHGTQKSSQAAMPHPEDLEDEWEVI
Sbjct: 1381 TKTFSHSHGTQKSSQAAMPHPEDLEDEWEVI 1411
>gi|31657123 Hermansky-Pudlak syndrome 5 isoform a [Homo sapiens]
Length = 1129
Score = 106 bits (265), Expect = 1e-22
Identities = 96/327 (29%), Positives = 149/327 (45%), Gaps = 24/327 (7%)
Query: 39 TALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTAS 98
T++ + ++A+GSS G L+L + + R + + +I+ V DD VA T+
Sbjct: 38 TSIAVSRKWLALGSSGGGLHLIQKEGWKHRLF-LSHREGAISQVACCLHDDDYVAVATSQ 96
Query: 99 GRVAVFQLVSSLPGRNKQLRRFDVTGIHKNS-ITALAWSPNGMKLFSGDDKGKIVYSSLD 157
G V V++L G+ +Q+ V+ HK +TAL W +++F GD GK+ L+
Sbjct: 97 GLVVVWELNQERRGKPEQMY---VSSEHKGRRVTALCWDTAILRVFVGDHAGKVSAIKLN 153
Query: 158 LDQG--------LCNSQLVLEEPSSIVQLDYSQKVLLVSTLQRSLLFYTEEKSVRQIGTQ 209
+ + Q + S +VQLDY LL+S+L RS L TE + +IG +
Sbjct: 154 TSKQAKAAAAFVMFPVQTITTVDSCVVQLDYLDGRLLISSLTRSFLCDTEREKFWKIGNK 213
Query: 210 PRKSTGKFGACFIPGLCKQSDLTL-YASRPGLRLWKADVHGTVQATFILKDAFAGGVKP- 267
R G++GACF PG C L Y +RPG R+W+ + G V +T K + P
Sbjct: 214 ER--DGEYGACFFPGRCSGGQQPLIYCARPGSRMWEVNFDGEVISTHQFKKLLSLPPLPV 271
Query: 268 --FELHPRLESPNSGSCSLPERHLGLVSCFFQEGWVLSWNEYSIYLLDTVNQATIAGLEG 325
P+ + S SL L E VL+W E IY+ N + E
Sbjct: 272 ITLRSEPQYDHTAGSSQSLSFPKL----LHLSEHCVLTWTERGIYIFIPQNVQVLLWSEV 327
Query: 326 SGDIVSVSCTENEIFFLKGDRNIIRIS 352
DI V+ NE+F L + + +S
Sbjct: 328 K-DIQDVAVCRNELFCLHLNGKVSHLS 353
>gi|31657125 Hermansky-Pudlak syndrome 5 isoform b [Homo sapiens]
Length = 1015
Score = 88.2 bits (217), Expect = 5e-17
Identities = 74/244 (30%), Positives = 108/244 (44%), Gaps = 20/244 (8%)
Query: 122 VTGIHKNS-ITALAWSPNGMKLFSGDDKGKIVYSSLDLDQG--------LCNSQLVLEEP 172
V+ HK +TAL W +++F GD GK+ L+ + + Q +
Sbjct: 3 VSSEHKGRRVTALCWDTAILRVFVGDHAGKVSAIKLNTSKQAKAAAAFVMFPVQTITTVD 62
Query: 173 SSIVQLDYSQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLT 232
S +VQLDY LL+S+L RS L TE + +IG + R G++GACF PG C
Sbjct: 63 SCVVQLDYLDGRLLISSLTRSFLCDTEREKFWKIGNKER--DGEYGACFFPGRCSGGQQP 120
Query: 233 L-YASRPGLRLWKADVHGTVQATFILKDAFAGGVKP---FELHPRLESPNSGSCSLPERH 288
L Y +RPG R+W+ + G V +T K + P P+ + S SL
Sbjct: 121 LIYCARPGSRMWEVNFDGEVISTHQFKKLLSLPPLPVITLRSEPQYDHTAGSSQSLSFPK 180
Query: 289 LGLVSCFFQEGWVLSWNEYSIYLLDTVNQATIAGLEGSGDIVSVSCTENEIFFLKGDRNI 348
L E VL+W E IY+ N + E DI V+ NE+F L + +
Sbjct: 181 L----LHLSEHCVLTWTERGIYIFIPQNVQVLLWSEVK-DIQDVAVCRNELFCLHLNGKV 235
Query: 349 IRIS 352
+S
Sbjct: 236 SHLS 239
>gi|31657127 Hermansky-Pudlak syndrome 5 isoform b [Homo sapiens]
Length = 1015
Score = 88.2 bits (217), Expect = 5e-17
Identities = 74/244 (30%), Positives = 108/244 (44%), Gaps = 20/244 (8%)
Query: 122 VTGIHKNS-ITALAWSPNGMKLFSGDDKGKIVYSSLDLDQG--------LCNSQLVLEEP 172
V+ HK +TAL W +++F GD GK+ L+ + + Q +
Sbjct: 3 VSSEHKGRRVTALCWDTAILRVFVGDHAGKVSAIKLNTSKQAKAAAAFVMFPVQTITTVD 62
Query: 173 SSIVQLDYSQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLT 232
S +VQLDY LL+S+L RS L TE + +IG + R G++GACF PG C
Sbjct: 63 SCVVQLDYLDGRLLISSLTRSFLCDTEREKFWKIGNKER--DGEYGACFFPGRCSGGQQP 120
Query: 233 L-YASRPGLRLWKADVHGTVQATFILKDAFAGGVKP---FELHPRLESPNSGSCSLPERH 288
L Y +RPG R+W+ + G V +T K + P P+ + S SL
Sbjct: 121 LIYCARPGSRMWEVNFDGEVISTHQFKKLLSLPPLPVITLRSEPQYDHTAGSSQSLSFPK 180
Query: 289 LGLVSCFFQEGWVLSWNEYSIYLLDTVNQATIAGLEGSGDIVSVSCTENEIFFLKGDRNI 348
L E VL+W E IY+ N + E DI V+ NE+F L + +
Sbjct: 181 L----LHLSEHCVLTWTERGIYIFIPQNVQVLLWSEVK-DIQDVAVCRNELFCLHLNGKV 235
Query: 349 IRIS 352
+S
Sbjct: 236 SHLS 239
>gi|32698704 tectonin beta-propeller repeat containing 1 [Homo
sapiens]
Length = 1165
Score = 70.1 bits (170), Expect = 1e-11
Identities = 52/182 (28%), Positives = 79/182 (43%), Gaps = 13/182 (7%)
Query: 1180 ALWALDSLGQVFIRT-LSKSCPTGMHWTRLDLSQLGAVKLTSLACG-NQHIWACDSRGGV 1237
++WA+ G+V+ R +S S P G W+ LD ++ ++CG + +WA G
Sbjct: 210 SVWAVSLQGKVWYREDVSHSNPEGSSWSLLDTPG----EVVQISCGPHDLLWATLWEGQA 265
Query: 1238 YFRVGTQPLNPSLMLPAWIMIEPPVQPAGVSLVSVHSSPNDQMLWVLDSRWNVHVRTGIT 1297
R G NP +W ++EPP GV +SV S ++W + W V R G+
Sbjct: 266 LVREGINRSNPKGS--SWSIVEPPGSENGVMHISVGVS----VVWAVTKDWKVWFRRGVN 319
Query: 1298 EEMPVGTAWEHVPGLQACQLALSTRTVWA-RCPNGDLARRYGVTDKNPAGDYWKKIPGSV 1356
P GT+W + G VW C + + R GVT +G WK I +
Sbjct: 320 SHNPCGTSWIEMVGEMTMVNVGMNDQVWGIGCEDRAVYFRQGVTPSELSGKTWKAIIAAR 379
Query: 1357 SC 1358
C
Sbjct: 380 EC 381
Score = 66.6 bits (161), Expect = 2e-10
Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 13/167 (7%)
Query: 1209 DLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEPPVQPAGVS 1268
DLS +G ++T G +WA +G V++R NP +W +++ P +
Sbjct: 193 DLS-VGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHSNPEGS--SWSLLDTPGE----- 244
Query: 1269 LVSVHSSPNDQMLWVLDSRWNVHVRTGITEEMPVGTAWEHV--PGLQ--ACQLALSTRTV 1324
+V + P+D +LW VR GI P G++W V PG + +++ V
Sbjct: 245 VVQISCGPHD-LLWATLWEGQALVREGINRSNPKGSSWSIVEPPGSENGVMHISVGVSVV 303
Query: 1325 WARCPNGDLARRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVG 1371
WA + + R GV NP G W ++ G ++ V +D++W +G
Sbjct: 304 WAVTKDWKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGMNDQVWGIG 350
Score = 62.4 bits (150), Expect = 3e-09
Identities = 41/176 (23%), Positives = 74/176 (42%), Gaps = 17/176 (9%)
Query: 1228 IWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEPPVQPAGVSLVSVHSSPNDQMLWVLDSR 1287
+WA +G V R+G LNP+ +W+ + A +S+ + + +W +
Sbjct: 955 LWAVSDKGDVLCRLGVSELNPAGS--SWLHVGTDQPFASISIGACYQ------VWAVARD 1006
Query: 1288 WNVHVRTGITEEMPVGTAWEHVPG---LQACQLALSTRTVWARCPNGDLARRYGVTDKNP 1344
+ R + P G W H+P + Q++ +V+A NG+L R G+T P
Sbjct: 1007 GSAFYRGSVYPSQPAGDCWYHIPSPPRQRLKQVSAGQTSVYALDENGNLWYRQGITPSYP 1066
Query: 1345 AGDYWKKIPGSVSCFTVTASDELWAVGPPGYLLQRLTKTFSHSHGTQKSSQAAMPH 1400
G W+ + +V +V D++W + ++ + S S GT PH
Sbjct: 1067 QGSSWEHVSNNVCRVSVGPLDQVWVIA------NKVQGSHSLSRGTVCHRTGVQPH 1116
Score = 55.5 bits (132), Expect = 4e-07
Identities = 41/126 (32%), Positives = 56/126 (44%), Gaps = 9/126 (7%)
Query: 905 WIIRTSGDLYLQTGLSVDRPCARA---VKVDCPYPLSQITARNNVVWALTEQRALLYREG 961
W + GD+ + G+S P + V D P+ I A V WA+ + YR
Sbjct: 956 WAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASISIGACYQV-WAVARDGSAFYRGS 1014
Query: 962 VSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDDD 1021
V P G+ W RQ L+ V Q +++ALD +GNLW+R GI PQG
Sbjct: 1015 VYPSQPAGDCWYHIPSPPRQRLKQVS---AGQTSVYALDENGNLWYRQGITPSYPQGSS- 1070
Query: 1022 HWWQVS 1027
W VS
Sbjct: 1071 -WEHVS 1075
Score = 40.8 bits (94), Expect = 0.009
Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 4/118 (3%)
Query: 903 TAWIIRTSGDLYLQTGLSVDRPCARAVKV-DCPYPLSQITAR-NNVVWALTEQRALLYRE 960
+ W + G ++ + +S P + + D P + QI+ ++++WA + L RE
Sbjct: 210 SVWAVSLQGKVWYREDVSHSNPEGSSWSLLDTPGEVVQISCGPHDLLWATLWEGQALVRE 269
Query: 961 GVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQG 1018
G++ P+G W IV + V +WA+ +WFR G+ S P G
Sbjct: 270 GINRSNPKGSSW--SIVEPPGSENGVMHISVGVSVVWAVTKDWKVWFRRGVNSHNPCG 325
Score = 39.7 bits (91), Expect = 0.021
Identities = 45/187 (24%), Positives = 78/187 (41%), Gaps = 21/187 (11%)
Query: 1179 DALWALDSLGQVFIRT-LSKSCPTGMHWTRLDL--SQLGAVKLTSLACGNQHIWACDSRG 1235
D LWA GQ +R +++S P G W+ ++ S+ G + ++ G +WA
Sbjct: 254 DLLWATLWEGQALVREGINRSNPKGSSWSIVEPPGSENGVMHIS---VGVSVVWAVTKDW 310
Query: 1236 GVYFRVGTQPLNPSLMLPAWIMIEPPVQPAGVSLVSVHSSPNDQMLWVLDSRWNVHVRTG 1295
V+FR G NP +WI + + V + NDQ+ + V+ R G
Sbjct: 311 KVWFRRGVNSHNPCGT--SWIEMVGEMTMVNVGM-------NDQVWGIGCEDRAVYFRQG 361
Query: 1296 ITEEMPVGTAWEHVPGLQACQLA---LSTRTVWARCPNGDLARRYG---VTDKNPAGDYW 1349
+T G W+ + + C + S+ + A C GD R G +D + + +
Sbjct: 362 VTPSELSGKTWKAIIAARECDRSHSGSSSSLLSAGCFFGDEVRGSGESAPSDTDASSEVE 421
Query: 1350 KKIPGSV 1356
+ PG +
Sbjct: 422 RPGPGQI 428
Score = 39.3 bits (90), Expect = 0.027
Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 6/128 (4%)
Query: 919 LSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYREGVSSFCPEGEQWKCDIVS 978
L V R V + P ++ + + +WA++++ +L R GVS P G W V
Sbjct: 927 LEVPPIALRDVSIIPESPGAEGSGHSIALWAVSDKGDVLCRLGVSELNPAGSSWL--HVG 984
Query: 979 ERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDDDHWWQVSITDYVVFDQCS 1038
Q I++G +WA+ G+ ++R + +P G D W+ + Q S
Sbjct: 985 TDQPF--ASISIGACYQVWAVARDGSAFYRGSVYPSQPAG--DCWYHIPSPPRQRLKQVS 1040
Query: 1039 LFQTIIHA 1046
QT ++A
Sbjct: 1041 AGQTSVYA 1048
Score = 36.2 bits (82), Expect = 0.23
Identities = 37/138 (26%), Positives = 57/138 (41%), Gaps = 22/138 (15%)
Query: 1181 LWALDSLGQVFIR-TLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYF 1239
+WA+ G F R ++ S P G W + +L ++ G ++A D G +++
Sbjct: 1000 VWAVARDGSAFYRGSVYPSQPAGDCWYHIPSPP--RQRLKQVSAGQTSVYALDENGNLWY 1057
Query: 1240 RVGTQPLNPSLMLPAWIMIEPPVQPAGVSLVSVHSSPNDQMLWVLD---------SRWNV 1290
R G P P +W + V VSV P DQ+ WV+ SR V
Sbjct: 1058 RQGITPSYPQGS--SWEHVSN-----NVCRVSV--GPLDQV-WVIANKVQGSHSLSRGTV 1107
Query: 1291 HVRTGITEEMPVGTAWEH 1308
RTG+ P G W++
Sbjct: 1108 CHRTGVQPHEPKGHGWDY 1125
Score = 35.0 bits (79), Expect = 0.51
Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 13/123 (10%)
Query: 902 DTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQ-----ITARNNVVWALTEQRAL 956
D W G ++ G++ P + + P P S+ I+ +VVWA+T+ +
Sbjct: 254 DLLWATLWEGQALVREGINRSNPKGSSWSIVEP-PGSENGVMHISVGVSVVWAVTKDWKV 312
Query: 957 LYREGVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGN-LWFRTGIISKK 1015
+R GV+S P G W ++V E + +G +W + ++FR G+ +
Sbjct: 313 WFRRGVNSHNPCGTSW-IEMVGEM-----TMVNVGMNDQVWGIGCEDRAVYFRQGVTPSE 366
Query: 1016 PQG 1018
G
Sbjct: 367 LSG 369
Score = 33.5 bits (75), Expect = 1.5
Identities = 26/91 (28%), Positives = 40/91 (43%), Gaps = 11/91 (12%)
Query: 1166 PPEAEMRAYAACQDALWALDSLGQVFIRT-LSKSCPTGMHW-------TRLDLSQLGAVK 1217
PP ++ +A Q +++ALD G ++ R ++ S P G W R+ + L V
Sbjct: 1031 PPRQRLKQVSAGQTSVYALDENGNLWYRQGITPSYPQGSSWEHVSNNVCRVSVGPLDQVW 1090
Query: 1218 LTSLACGNQHIWACDSRGGVYFRVGTQPLNP 1248
+ + H SRG V R G QP P
Sbjct: 1091 VIANKVQGSHSL---SRGTVCHRTGVQPHEP 1118
Score = 30.8 bits (68), Expect = 9.6
Identities = 17/84 (20%), Positives = 40/84 (47%), Gaps = 3/84 (3%)
Query: 897 VALSDDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITA-RNNVVWAL-TEQR 954
+++ W + ++ + G++ PC + ++ ++ + N+ VW + E R
Sbjct: 296 ISVGVSVVWAVTKDWKVWFRRGVNSHNPCGTSW-IEMVGEMTMVNVGMNDQVWGIGCEDR 354
Query: 955 ALLYREGVSSFCPEGEQWKCDIVS 978
A+ +R+GV+ G+ WK I +
Sbjct: 355 AVYFRQGVTPSELSGKTWKAIIAA 378
>gi|16757970 niban protein isoform 2 [Homo sapiens]
Length = 928
Score = 47.4 bits (111), Expect = 1e-04
Identities = 75/270 (27%), Positives = 105/270 (38%), Gaps = 39/270 (14%)
Query: 355 PEGLTSTVRDGLEMSGCSERVHVQQAEK-LPGATVSETRLRGSSMASSVASEPRSRSSSL 413
P S++ D +G ++ ++A LPG SET S +P SS
Sbjct: 576 PSESVSSLTDLKPPTGSNQASPARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLA 635
Query: 414 NSTDSGSGLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTE 473
G L PG P+ G++ + IS D + VV P+ +
Sbjct: 636 K----GESLSLPGPSPPPD---GTEQV-----IISRVD---DPVVNPVATE-------DT 673
Query: 474 GGSRSTCHSSLE--STPCSEFPG-DSPQSLNTD-LLSMTSSVLGSSVDQLSAESPDQESS 529
G TC S LE T E P + P+ + L +L +SV+ +P E
Sbjct: 674 AGLPGTCSSELEFGGTLEDEEPAQEEPEPITASGSLKALRKLLTASVEVPVDSAPVMEED 733
Query: 530 FNGEVNGVPQENTDPETFNVLEVSGSMPDSLAE-EDDIRTEMPHCHHAHGRELLNGARED 588
NGE + VPQEN + E + + PD+ E E R P C AHG EL G +
Sbjct: 734 TNGESH-VPQENEEEEEKEPSQAAAIHPDNCEESEVSEREAQPPCPEAHGEEL--GGFPE 790
Query: 589 VGGSDVT----GLGDEPCPADDGPNSTQLP 614
VG GL +EP GP +LP
Sbjct: 791 VGSPASPPASGGLTEEPL----GPMEGELP 816
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 38.9 bits (89), Expect = 0.035
Identities = 53/248 (21%), Positives = 97/248 (39%), Gaps = 37/248 (14%)
Query: 402 VASEPRSRSSSLNSTD--------SGSGLLP-PGLQATP------ELGKGSQPLSQRFNA 446
V SE R SSS S + SGLLP P ++ P + S P +F
Sbjct: 2653 VTSESRKVSSSSESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQP 2712
Query: 447 ISSEDF----DQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSLNT 502
+ S+ + +++ +P K + +K + R + E + D+ Q
Sbjct: 2713 VVSKQYTFKMNEDTQEEPGKSEEEKDSESHLAEDRHAVSTEAEDRSYDKLNRDTDQPKIC 2772
Query: 503 D-----LLSMTSSV--LGSSVDQLSAESPDQESSFNGE---VNGVPQENTDPETFNVLEV 552
D +S +SS + S + + + D++ E + G +++T+ E +V
Sbjct: 2773 DGHGCEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEKDTEGEELDVSRA 2832
Query: 553 SGSMPDSLAEEDDIRTEMPHCHHAHGRELLN--GAREDVGGSDVTGLGD------EPCPA 604
D +E + +PHC + G+EL A + ++VT + + CP+
Sbjct: 2833 ESPQADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTDETFENLPKDCPS 2892
Query: 605 DDGPNSTQ 612
D +TQ
Sbjct: 2893 QDSSITTQ 2900
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 38.1 bits (87), Expect = 0.060
Identities = 42/160 (26%), Positives = 61/160 (38%), Gaps = 9/160 (5%)
Query: 357 GLTSTVRDGLEMSGCSE---RVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSL 413
G+ S G+ S E QQ L ++ R SS +SS +S S SSS
Sbjct: 2492 GMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS 2551
Query: 414 NSTDSGSGLLP---PGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKK 470
+S+ SGS L PE+ P E + +P KRK++
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPSP---TPAPKEAVREGRPPEPTPAKRKRRSS 2608
Query: 471 KTEGGSRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSS 510
+ S S+ SS S+ S S S ++ S +SS
Sbjct: 2609 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
>gi|157388929 epsin 3 [Homo sapiens]
Length = 632
Score = 37.4 bits (85), Expect = 0.10
Identities = 47/186 (25%), Positives = 67/186 (36%), Gaps = 35/186 (18%)
Query: 630 IQPIGPQSTFC-----EVPLLNSLTVPSSLSWAPSAEQWLPGTRADEGSPVEPSQEQDIL 684
+ + P ST C ++P T S SW PSA+ W P G+ + SQ D+
Sbjct: 308 VPALAPPSTHCSADPWDIPGFRPNTEASGSSWGPSADPWSP---IPSGTVLSRSQPWDLT 364
Query: 685 TSMEAS-----------GHLSTNLWHAVTD----DDTGQKEIPISERVLGSVGGQLTPVS 729
+ +S G +T+ W + TG S + GG
Sbjct: 365 PMLSSSEPWGRTPVLPAGPPTTDPWALNSPHHKLPSTGADPWGASLETSDTPGG------ 418
Query: 730 ALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSV-TELGPSCSQQDLSRLGA 788
AST P+ + P + T T E G PSS E + + PS Q A
Sbjct: 419 ---ASTFDPFAKPP--ESTETKEGLEQALPSGKPSSPVELDLFGDPSPSSKQNGTKEPDA 473
Query: 789 EDAGLL 794
D G+L
Sbjct: 474 LDLGIL 479
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 37.0 bits (84), Expect = 0.13
Identities = 39/168 (23%), Positives = 70/168 (41%), Gaps = 18/168 (10%)
Query: 462 KVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSA 521
K KK+KK + GSRS +S ++ S F P SS G +++ A
Sbjct: 294 KPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKP-------AKDKSSTRG---EKVKA 343
Query: 522 ESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEM---PHCHHAHG 578
ES +E+ EV + N++ E E + S P + + D ++ P +H+ G
Sbjct: 344 ESEPREAKKALEVE---ESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQG 400
Query: 579 --RELLNGAREDVGGSDVTGLGDEPCPADDGPNSTQLPFQEQDSSPGA 624
R ++ + + D + G+E + ++L F + +S A
Sbjct: 401 PLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSA 448
>gi|199559532 Abelson helper integration site 1 isoform b [Homo
sapiens]
Length = 1053
Score = 35.8 bits (81), Expect = 0.30
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)
Query: 35 VVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAA 94
++Y + + YI SS G ++ +N + + K +LV
Sbjct: 656 IIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVT 715
Query: 95 GTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIV 152
G + +++ V +R+FDV HK+ I +L + G ++SGD G IV
Sbjct: 716 GCYDSMIRIWK-VEMREDSAILVRQFDV---HKSFINSLCFDTEGHHMYSGDCTGVIV 769
>gi|199559490 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 35.8 bits (81), Expect = 0.30
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)
Query: 35 VVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAA 94
++Y + + YI SS G ++ +N + + K +LV
Sbjct: 656 IIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVT 715
Query: 95 GTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIV 152
G + +++ V +R+FDV HK+ I +L + G ++SGD G IV
Sbjct: 716 GCYDSMIRIWK-VEMREDSAILVRQFDV---HKSFINSLCFDTEGHHMYSGDCTGVIV 769
>gi|199559438 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 35.8 bits (81), Expect = 0.30
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)
Query: 35 VVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAA 94
++Y + + YI SS G ++ +N + + K +LV
Sbjct: 656 IIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVT 715
Query: 95 GTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIV 152
G + +++ V +R+FDV HK+ I +L + G ++SGD G IV
Sbjct: 716 GCYDSMIRIWK-VEMREDSAILVRQFDV---HKSFINSLCFDTEGHHMYSGDCTGVIV 769
>gi|31542701 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 35.8 bits (81), Expect = 0.30
Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)
Query: 35 VVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAA 94
++Y + + YI SS G ++ +N + + K +LV
Sbjct: 656 IIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVT 715
Query: 95 GTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIV 152
G + +++ V +R+FDV HK+ I +L + G ++SGD G IV
Sbjct: 716 GCYDSMIRIWK-VEMREDSAILVRQFDV---HKSFINSLCFDTEGHHMYSGDCTGVIV 769
>gi|31652242 transcription factor 20 isoform 2 [Homo sapiens]
Length = 1938
Score = 35.8 bits (81), Expect = 0.30
Identities = 47/222 (21%), Positives = 81/222 (36%), Gaps = 25/222 (11%)
Query: 426 GLQATPELGKGSQPLSQRFNAISSEDFD-----QELVVKPIKVKRKKKKKKTEGGSRSTC 480
GL+ PE LS +A+S++ + Q +++ +KK K+ ++
Sbjct: 439 GLEGVPEKRLTDPGLSS-LSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADS 497
Query: 481 HSSLESTPCSEFPGDSPQSLNTDL-LSMTSSVLGSSVDQLSAESPDQESSFNGEV----- 534
++ E + E SP + + D S +S G V QLS +S ++++ G
Sbjct: 498 CTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAG 557
Query: 535 --------NGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAR 586
N P+ N P G+ L+ + + + RE + G
Sbjct: 558 SSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRV 617
Query: 587 EDVGGSDVTGLGDEPC-----PADDGPNSTQLPFQEQDSSPG 623
E GG D D+P P++ G T Q PG
Sbjct: 618 EKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPG 659
>gi|31652244 transcription factor 20 isoform 1 [Homo sapiens]
Length = 1960
Score = 35.8 bits (81), Expect = 0.30
Identities = 47/222 (21%), Positives = 81/222 (36%), Gaps = 25/222 (11%)
Query: 426 GLQATPELGKGSQPLSQRFNAISSEDFD-----QELVVKPIKVKRKKKKKKTEGGSRSTC 480
GL+ PE LS +A+S++ + Q +++ +KK K+ ++
Sbjct: 439 GLEGVPEKRLTDPGLSS-LSALSTQVANLPNTVQHMLLSDALTPQKKTSKRPSSSKKADS 497
Query: 481 HSSLESTPCSEFPGDSPQSLNTDL-LSMTSSVLGSSVDQLSAESPDQESSFNGEV----- 534
++ E + E SP + + D S +S G V QLS +S ++++ G
Sbjct: 498 CTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKGGASEKAG 557
Query: 535 --------NGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAR 586
N P+ N P G+ L+ + + + RE + G
Sbjct: 558 SSPAQGAQNEPPRLNASPAAREEATSPGAKDMPLSSDGNPKVNEKTVGVIVSREAMTGRV 617
Query: 587 EDVGGSDVTGLGDEPC-----PADDGPNSTQLPFQEQDSSPG 623
E GG D D+P P++ G T Q PG
Sbjct: 618 EKPGGQDKGSQEDDPAATQRPPSNGGAKETSHASLPQPEPPG 659
>gi|4557515 damage-specific DNA binding protein 2 [Homo sapiens]
Length = 427
Score = 35.4 bits (80), Expect = 0.39
Identities = 31/133 (23%), Positives = 62/133 (46%), Gaps = 16/133 (12%)
Query: 33 SIVVYLTALDTNGD--YIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDD 90
+I ++ +LD + + G ++G + L +++ +N + +T V L C D
Sbjct: 199 TINIWFCSLDVSASSRMVVTGDNVGNVILL--NMDGKELWNLRMHKKKVTHVALNPCCDW 256
Query: 91 LVAAGTASGRVAVFQLVSSLPGRNKQLR---RFDVTGIHKNSITALAWSPNGMKLFSGDD 147
+A + V ++ L +Q+R F + H++ + A +SP+G +L + D
Sbjct: 257 FLATASVDQTVKIWDL--------RQVRGKASFLYSLPHRHPVNAACFSPDGARLLTTDQ 308
Query: 148 KGKI-VYSSLDLD 159
K +I VYS+ D
Sbjct: 309 KSEIRVYSASQWD 321
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 35.4 bits (80), Expect = 0.39
Identities = 82/329 (24%), Positives = 120/329 (36%), Gaps = 47/329 (14%)
Query: 466 KKKKKKTEGGSRSTCHSSLESTPCSE--FPGDSPQSLNTDLLSMTSSVLGSSVDQLSAES 523
K+K++ T G S H S+P ++ +P L + L+ SS G V Q+S +
Sbjct: 32 KRKQQDTPG---SPDHRDASSSPVADDIIQPAAPADLESPTLA-ASSYHGDVVGQVSTDL 87
Query: 524 PDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLN 583
Q SS + E P+ T + P + E ++ T+ P
Sbjct: 88 IAQRSSDSEEAFETPESTTPVKA---PPAPPPPPPEVIPEPEVSTQPP------------ 132
Query: 584 GAREDVGGSDVTGLGDEPCPADDGPNSTQL---PFQEQDSSPGAHDGEDIQPIGPQST-- 638
+ G G E P DGP S + PF+ S A ED +PI T
Sbjct: 133 --------PEEPGCGSETVPVPDGPRSDSVEGSPFRPPSHSFSAVFDED-KPIASSGTYN 183
Query: 639 --FCEVPLLNSL-TVPSSLSWAPSAEQWLPGTRADEGS-PVEPSQEQDILTSMEAS---G 691
F + L+++ T+ S A + E + R S P+ S L S++AS G
Sbjct: 184 LDFDNIELVDTFQTLEPRASDAKNQEGKVNTRRKSTDSVPISKSTLSRSL-SLQASDFDG 242
Query: 692 HLSTNLWHAVT-DDDTGQKEIPISERVLGSVGGQLTPVSALAASTHKPWLEQPPRDQTLT 750
S+ AV D + L P +T KP E PP +T
Sbjct: 243 ASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKP-TETPPVKETQQ 301
Query: 751 SSDEEDIYAHG--LPSSSSETSVTELGPS 777
DEE + G L S + S GPS
Sbjct: 302 EPDEESLVPSGENLASETKTESAKTEGPS 330
>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
Length = 1992
Score = 34.7 bits (78), Expect = 0.67
Identities = 52/186 (27%), Positives = 73/186 (39%), Gaps = 31/186 (16%)
Query: 365 GLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLP 424
G E +G ER A+ A+ S T + + +S S SSS ++ S S +P
Sbjct: 162 GSESTGAEER----SAKPTKLASKSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVP 217
Query: 425 PGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGS------RS 478
PG A + GK Q ++R + SS P + R+K++ KT G S R
Sbjct: 218 PG--ARVKQGK-DQNKARRSRSASSP--------SPRRSSREKEQSKTGGSSKFDWAARF 266
Query: 479 TCHSSLESTPCSEFPGDS--------PQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSF 530
+ SL T S PG S P L L S+ S S + AE P S
Sbjct: 267 SPKVSLPKTKLS-LPGSSKSETSKPGPSGLQAKLASLRKSTKKRS-ESPPAELPSLRRST 324
Query: 531 NGEVNG 536
+ G
Sbjct: 325 RQKTTG 330
Score = 33.5 bits (75), Expect = 1.5
Identities = 49/170 (28%), Positives = 64/170 (37%), Gaps = 12/170 (7%)
Query: 372 SERVHVQQAEKLPGATVSETRLRGS-SMASSVASEPRSRSSSLNSTDS-GSGLLPPGLQA 429
S V V Q E A SE + G + RS S N T+S S P LQ
Sbjct: 38 SSAVIVPQPEDPDRANTSERQKTGQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPKALQH 97
Query: 430 TPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRS-----TCHSSL 484
T + ++P S+ ++ + P K +K GGSRS T S +
Sbjct: 98 TESPSETNKPHSKSKKRHLDQEQQLKSAQSPSTSKAHTRKSGATGGSRSQKRKRTESSCV 157
Query: 485 ESTPCSEFPGDSPQSLNTDLL---SMTSSVLGSS--VDQLSAESPDQESS 529
+S SE G +S L S TS+ G S D SA S SS
Sbjct: 158 KSGSGSESTGAEERSAKPTKLASKSATSAKAGCSTITDSSSAASTSSSSS 207
>gi|41281447 intraflagellar transport 140 [Homo sapiens]
Length = 1462
Score = 34.7 bits (78), Expect = 0.67
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 8/67 (11%)
Query: 91 LVAAGTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGK 150
++A G +G V VF ++K+ +T H IT L WSP+G L SGD G
Sbjct: 75 VLAVGWETGEVTVFNK------QDKEQHTMPLT--HTADITVLRWSPSGNCLLSGDRLGV 126
Query: 151 IVYSSLD 157
++ LD
Sbjct: 127 LLLWRLD 133
>gi|82830424 gon-4-like isoform a [Homo sapiens]
Length = 2240
Score = 34.3 bits (77), Expect = 0.87
Identities = 50/233 (21%), Positives = 78/233 (33%), Gaps = 15/233 (6%)
Query: 476 SRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVN 535
+R S E C + + L+T S S G Q + ++E S +
Sbjct: 1332 AREEISGSPERDICDDIKVEHAVELDTGAPSEELSSAGEVTKQTVLQK-EEERSQPTKTP 1390
Query: 536 GVPQENTDPETFNVLEVSGSMPDSLAEED-DIRTEMPHCHHAHGRELLNGAREDVGGSDV 594
QE D T GS ++L+ D ++R P G ED D
Sbjct: 1391 SSSQEPPDEGTSGTDVNKGSSKNALSSMDPEVRLSSPP-----------GKPEDSSSVDG 1439
Query: 595 TGLGDEPCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSL 654
+G P G + +E+D D ED + + VP L L
Sbjct: 1440 QSVGTPVGPETGGEKNGPEEEEEEDFDDLTQDEEDEMSSASEESVLSVPELQE--TMEKL 1497
Query: 655 SWAPSAEQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTG 707
+W S + ++E + E + E + EA G S +TD+ G
Sbjct: 1498 TWLASERRMSQEGESEEENSQEENSEPEEEEEEEAEGMESLQKEDEMTDEAVG 1550
>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
Length = 498
Score = 34.3 bits (77), Expect = 0.87
Identities = 14/40 (35%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 126 HKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNS 165
H++S+T++AW+P+G + +G +G+ + DLD L +S
Sbjct: 282 HEDSLTSVAWNPDGKRFVTGGQRGQ--FYQCDLDGNLLDS 319
>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
Length = 514
Score = 34.3 bits (77), Expect = 0.87
Identities = 14/40 (35%), Positives = 27/40 (67%), Gaps = 2/40 (5%)
Query: 126 HKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNS 165
H++S+T++AW+P+G + +G +G+ + DLD L +S
Sbjct: 298 HEDSLTSVAWNPDGKRFVTGGQRGQ--FYQCDLDGNLLDS 335
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 33.9 bits (76), Expect = 1.1
Identities = 32/167 (19%), Positives = 62/167 (37%), Gaps = 6/167 (3%)
Query: 614 PFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSAEQWLPGTRADEGS 673
P + ++ +P A++ + P P P N T PSS E+ S
Sbjct: 879 PTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPS 938
Query: 674 PVEPSQEQDILTSMEASGHLSTNLWH---AVTDDDTGQKEIPISERVLGSVGGQLTPVSA 730
EP++ + + + +A+ + H V +D T P + + T S
Sbjct: 939 RAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSP 998
Query: 731 LAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPS 777
++ H E+ ++T S E + PS++ +T + P+
Sbjct: 999 TESTEHG---ERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPT 1042
>gi|242117953 SH3 domain-containing protein C1orf113 isoform 1 [Homo
sapiens]
Length = 756
Score = 33.9 bits (76), Expect = 1.1
Identities = 44/192 (22%), Positives = 71/192 (36%), Gaps = 23/192 (11%)
Query: 381 EKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLPPGLQATPELGKGSQPL 440
+KL AT ++ + S S + + SR S N G PG K S+
Sbjct: 275 KKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGR-------KRSKTQ 327
Query: 441 SQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSL 500
+ + ++SS++ + VK VKR KT R + S+ P P
Sbjct: 328 TPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPE 387
Query: 501 NTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPD-S 559
T L +S+ G+S S + P P + PE E S+P+ S
Sbjct: 388 KTLTLGDKASIPGNST---SGKIP------------APDKVPTPEKMVTPEDKASIPENS 432
Query: 560 LAEEDDIRTEMP 571
+ E+ + + P
Sbjct: 433 IIPEETLTVDKP 444
>gi|242117948 SH3 domain-containing protein C1orf113 isoform 2 [Homo
sapiens]
Length = 645
Score = 33.9 bits (76), Expect = 1.1
Identities = 44/192 (22%), Positives = 71/192 (36%), Gaps = 23/192 (11%)
Query: 381 EKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLPPGLQATPELGKGSQPL 440
+KL AT ++ + S S + + SR S N G PG K S+
Sbjct: 164 KKLATATTGPSKAKTSRTPSRDSQKLTSRDSGPNGGFQSGGSYHPGR-------KRSKTQ 216
Query: 441 SQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSL 500
+ + ++SS++ + VK VKR KT R + S+ P P
Sbjct: 217 TPQQRSVSSQEEEHSSPVKAPSVKRTPMPDKTATPERPPAPENAPSSKKIPAPDKVPSPE 276
Query: 501 NTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPD-S 559
T L +S+ G+S S + P P + PE E S+P+ S
Sbjct: 277 KTLTLGDKASIPGNST---SGKIP------------APDKVPTPEKMVTPEDKASIPENS 321
Query: 560 LAEEDDIRTEMP 571
+ E+ + + P
Sbjct: 322 IIPEETLTVDKP 333
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 33.9 bits (76), Expect = 1.1
Identities = 76/420 (18%), Positives = 132/420 (31%), Gaps = 60/420 (14%)
Query: 372 SERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLPPGLQATP 431
SE V +AE + E + V ++P+S + T
Sbjct: 1997 SEDVEAPEAE----GEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEG----------ETQ 2042
Query: 432 ELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSE 491
+ +QP S A +E+ QE + + ++ EG + H E E
Sbjct: 2043 KTEGDAQPESDGVEAPEAEEEAQEA---------EGEVQEAEGEA----HPESEDVDAQE 2089
Query: 492 FPGDS-PQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQENTDPETFNVL 550
G++ P+S + G + E+P+ E E G+ + E
Sbjct: 2090 AEGEAQPESEGVE----APEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGE----- 2140
Query: 551 EVSGSMPDSLA-EEDDIRTE-MPHCHHAHGRELLNGAREDVGGSDVTGLGDEPCPADDGP 608
+ P+S E D E P +E A+ ++ G + E P +G
Sbjct: 2141 ----AQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGI 2196
Query: 609 NSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSAEQWLPGTR 668
+ + + Q G E + P+ E P P S ++ P
Sbjct: 2197 EAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVS 2256
Query: 669 ADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGSVGGQLTPV 728
+G E S+ V +D P + G Q P
Sbjct: 2257 LGDGQSEEASESSS-----------------PVPEDRPTPPPSPGGDTPHQRPGSQTGPS 2299
Query: 729 SALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQQDLSRLGA 788
S+ A+S W + D L + D + G P + + + S S+Q+ + LG+
Sbjct: 2300 SSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPESSTSEQEEAPLGS 2359
Score = 31.2 bits (69), Expect = 7.4
Identities = 43/186 (23%), Positives = 71/186 (38%), Gaps = 25/186 (13%)
Query: 462 KVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSA 521
+V+ ++ K+ TEG LE T E G + + L T G + A
Sbjct: 1300 EVQLEETKEGTEGEGLQEEAVQLEETKTEE--GLQEEGVQ---LEETKETEGEGQQEEEA 1354
Query: 522 ESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTE-MPHCHHAHGRE 580
+ + E + GE G+ +E E G ++L E+ ++ E +P HG+E
Sbjct: 1355 QLEEIEET-GGE--GLQEEGVQLEEVKEGPEGGLQGEAL--EEGLKEEGLPEEGSVHGQE 1409
Query: 581 LLNGAREDVGGSDV-----------TGLGDEPCPADDGPNSTQLPFQEQDSSPGAHD--- 626
L + D GS EPCPA+ T+ P ++ P A +
Sbjct: 1410 LSEASSPDGKGSQEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSHLSETDPSASERQS 1469
Query: 627 GEDIQP 632
G ++P
Sbjct: 1470 GSQLEP 1475
>gi|149944410 hypothetical protein LOC57587 [Homo sapiens]
Length = 532
Score = 33.9 bits (76), Expect = 1.1
Identities = 46/171 (26%), Positives = 67/171 (39%), Gaps = 27/171 (15%)
Query: 356 EGLTSTVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNS 415
EG DG E S ++ HV+ P V ++ + SS S SSSL+S
Sbjct: 126 EGEDDYYTDGEESSDDGKKYHVKSKSAKPSTNVKKSIRKKYCKVSS------SSSSSLSS 179
Query: 416 TDSGSGLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGG 475
+ SGSG T L GS + S + V I + K K K+ G
Sbjct: 180 SSSGSG--------TDCLDAGS---DSHLSDSSPSSKSSKKHVSGITLLSPKHKYKS--G 226
Query: 476 SRSTCHSSLESTP-CSEFPGDSPQSL-------NTDLLSMTSSVLGSSVDQ 518
+ST +TP C +P +S ++ D+ + S LG + DQ
Sbjct: 227 IKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIANDQ 277
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 33.5 bits (75), Expect = 1.5
Identities = 33/95 (34%), Positives = 38/95 (40%), Gaps = 13/95 (13%)
Query: 592 SDVTGLGDEPCPADDGPNSTQ-LPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTV 650
SDV L P P D P+ +P D SP P S +VP L S V
Sbjct: 236 SDVPSLSGVPSPPSDVPSLLSGVPSPPSDISP---------PSDVPSLLSDVPSLPS-DV 285
Query: 651 PSSLSWAPSAEQWLPGTRADEGSPVE--PSQEQDI 683
PS LS PS +P +D SP PS DI
Sbjct: 286 PSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDI 320
>gi|71565160 SMC1 structural maintenance of chromosomes 1-like 2 [Homo
sapiens]
Length = 1235
Score = 33.5 bits (75), Expect = 1.5
Identities = 17/56 (30%), Positives = 29/56 (51%)
Query: 1041 QTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSLLGVNNSGVWISSGKNE 1096
QT+I T + +Q +E + K +AF+ +Q Q Q LL + + + +S G E
Sbjct: 702 QTLIQGTQTRLKYSQNELEMIKKKHLVAFYQEQSQLQSELLNIESQCIMLSEGIKE 757
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,197,594
Number of Sequences: 37866
Number of extensions: 2871194
Number of successful extensions: 8814
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 105
Number of HSP's that attempted gapping in prelim test: 8563
Number of HSP's gapped (non-prelim): 322
length of query: 1411
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1296
effective length of database: 13,892,928
effective search space: 18005234688
effective search space used: 18005234688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.