Search of human proteins with 74271845

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
         (1454 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]              2927   0.0  
gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]           1070   0.0  
gi|162809334 pregnancy-zone protein [Homo sapiens]                    984   0.0  
gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]                    714   0.0  
gi|169204289 PREDICTED: ovostatin [Homo sapiens]                      686   0.0  
gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]         522   e-147
gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]         514   e-145
gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]         474   e-133
gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]         336   8e-92
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta...   302   2e-81
gi|178557739 complement component 4B preproprotein [Homo sapiens]     220   9e-57
gi|115298678 complement component 3 precursor [Homo sapiens]          219   1e-56
gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo s...   216   2e-55
gi|67190748 complement component 4A preproprotein [Homo sapiens]      215   3e-55
gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo s...   212   2e-54
gi|169218213 PREDICTED: similar to complement component C3, part...   181   3e-45
gi|38016947 complement component 5 preproprotein [Homo sapiens]       181   6e-45
gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...   129   2e-29
gi|239758130 PREDICTED: similar to complement component 4B (Chil...   125   3e-28
gi|239755748 PREDICTED: ovostatin [Homo sapiens]                      122   2e-27
gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...   110   1e-23
gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    82   4e-15
gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    76   3e-13
gi|239754277 PREDICTED: similar to Complement component 4A (Rodg...    62   4e-09
gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]             62   5e-09
gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sap...    62   5e-09
gi|169214179 PREDICTED: similar to complement component 3 [Homo ...    54   8e-07
gi|169217831 PREDICTED: similar to Ovostatin homolog 2 [Homo sap...    50   2e-05
gi|239755754 PREDICTED: ovostatin 2 [Homo sapiens]                     44   0.001
gi|170172518 microtubule associated monoxygenase, calponin and L...    33   2.0  

>gi|74271845 alpha-2-macroglobulin-like 1 [Homo sapiens]
          Length = 1454

 Score = 2927 bits (7588), Expect = 0.0
 Identities = 1454/1454 (100%), Positives = 1454/1454 (100%)

Query: 1    MWAQLLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKD 60
            MWAQLLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKD
Sbjct: 1    MWAQLLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKD 60

Query: 61   KTQKLLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGN 120
            KTQKLLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGN
Sbjct: 61   KTQKLLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGN 120

Query: 121  GTFVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGI 180
            GTFVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGI
Sbjct: 121  GTFVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGI 180

Query: 181  VDLSFQLAPEAMLGTYTVAVAEGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKI 240
            VDLSFQLAPEAMLGTYTVAVAEGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKI
Sbjct: 181  VDLSFQLAPEAMLGTYTVAVAEGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKI 240

Query: 241  CCRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMAT 300
            CCRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMAT
Sbjct: 241  CCRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMAT 300

Query: 301  FDLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGK 360
            FDLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGK
Sbjct: 301  FDLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGK 360

Query: 361  IRVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQ 420
            IRVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQ
Sbjct: 361  IRVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQ 420

Query: 421  MEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPAD 480
            MEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPAD
Sbjct: 421  MEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPAD 480

Query: 481  ASPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIF 540
            ASPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIF
Sbjct: 481  ASPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIF 540

Query: 541  PSGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLL 600
            PSGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLL
Sbjct: 541  PSGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLL 600

Query: 601  LRPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSII 660
            LRPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSII
Sbjct: 601  LRPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSII 660

Query: 661  WRPSFSEGTDLFSFFRDVGLKILSNAKIKKPVDCSHRSPEYSTAMGAGGGHPEAFESSTP 720
            WRPSFSEGTDLFSFFRDVGLKILSNAKIKKPVDCSHRSPEYSTAMGAGGGHPEAFESSTP
Sbjct: 661  WRPSFSEGTDLFSFFRDVGLKILSNAKIKKPVDCSHRSPEYSTAMGAGGGHPEAFESSTP 720

Query: 721  LHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSP 780
            LHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSP
Sbjct: 721  LHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSP 780

Query: 781  TVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADS 840
            TVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADS
Sbjct: 781  TVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADS 840

Query: 841  QTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKP 900
            QTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKP
Sbjct: 841  QTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKP 900

Query: 901  VLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNL 960
            VLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNL
Sbjct: 901  VLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNL 960

Query: 961  DGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSN 1020
            DGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSN
Sbjct: 961  DGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSN 1020

Query: 1021 GSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVG 1080
            GSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVG
Sbjct: 1021 GSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVG 1080

Query: 1081 NLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNSATSTTNLYTQALL 1140
            NLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNSATSTTNLYTQALL
Sbjct: 1081 NLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNSATSTTNLYTQALL 1140

Query: 1141 AYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTAYA 1200
            AYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTAYA
Sbjct: 1141 AYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTAYA 1200

Query: 1201 LLAQLTKPSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSE 1260
            LLAQLTKPSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSE
Sbjct: 1201 LLAQLTKPSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSE 1260

Query: 1261 EINLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILP 1320
            EINLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILP
Sbjct: 1261 EINLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILP 1320

Query: 1321 PTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEG 1380
            PTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEG
Sbjct: 1321 PTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEG 1380

Query: 1381 TNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYL 1440
            TNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYL
Sbjct: 1381 TNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYL 1440

Query: 1441 PDEQATIQYSDPCE 1454
            PDEQATIQYSDPCE
Sbjct: 1441 PDEQATIQYSDPCE 1454


>gi|66932947 alpha-2-macroglobulin precursor [Homo sapiens]
          Length = 1474

 Score = 1070 bits (2767), Expect = 0.0
 Identities = 598/1476 (40%), Positives = 875/1476 (59%), Gaps = 48/1476 (3%)

Query: 5    LLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQK 64
            LLL +L  + A     P Y+V +P+ L+  + +K C+ LS     V  + +LE+    + 
Sbjct: 13   LLLLVLLPTDASVSGKPQYMVLVPSLLHTETTEKGCVLLSYLNETVTVSASLESVRGNRS 72

Query: 65   LLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFV 124
            L      +   LHC++F VP  +   EEV  + V   G    F+++  V+++ + +  FV
Sbjct: 73   LFTDLEAENDVLHCVAFAVPK-SSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEDSLVFV 131

Query: 125  QTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLS 184
            QTDK +Y PGQ V FR+V+MD NF P+N+   +V +QDP  NRIAQW     E G+   S
Sbjct: 132  QTDKSIYKPGQTVKFRVVSMDENFHPLNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQFS 191

Query: 185  FQLAPEAMLGTYTVAVAE---GKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKIC 241
            F L+ E   G+Y V V +   G+T   F+VEE+VLPKF+V+V  PK ++ ++E   V +C
Sbjct: 192  FPLSSEPFQGSYKVVVQKKSGGRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVC 251

Query: 242  CRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATF 301
              YTYGKP+ G V VS+C+K +     +   E     C   SGQ +  GCF   V    F
Sbjct: 252  GLYTYGKPVPGHVTVSICRKYSDA--SDCHGEDSQAFCEKFSGQLNSHGCFYQQVKTKVF 309

Query: 302  DLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGKI 361
             L    Y  +++  A + EEGT VE    Q+  I+  +  ++F    + +    PF G++
Sbjct: 310  QLKRKEYEMKLHTEAQIQEEGTVVELTGRQSSEITRTITKLSFVKVDSHFRQGIPFFGQV 369

Query: 362  RVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQM 421
            R+       + N ++F  I G    +     TD +GL  F++ T+   GT +++   ++ 
Sbjct: 370  RLVDGKGVPIPNKVIF--IRGNEANYYSNATTDEHGLVQFSINTTNVMGTSLTVRVNYKD 427

Query: 422  EDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADA 481
                Y  + V   ++ A+      +S ++SF+ +  ++  L CG  Q V   Y ++    
Sbjct: 428  RSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPMSHELPCGHTQTVQAHYILNGGTL 487

Query: 482  SPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFP 541
               +++SF Y ++ KG +V  G   L  K++ +K  FS+S+   S +AP   L+IYA+ P
Sbjct: 488  LGLKKLSFYYLIMAKGGIVRTGTHGLLVKQEDMKGHFSISIPVKSDIAPVARLLIYAVLP 547

Query: 542  SGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLL 601
            +G V+ D  ++ VE C  N+V L FSPSQ LP +   L++ AAP S+CALRAVD+SVLL+
Sbjct: 548  TGDVIGDSAKYDVENCLANKVDLSFSPSQSLPASHAHLRVTAAPQSVCALRAVDQSVLLM 607

Query: 602  RPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIW 661
            +PD ELS  SVY + P           E D     GP +  Q   D + + +     I +
Sbjct: 608  KPDAELSASSVYNLLP-----------EKDLTGFPGPLN-DQDDEDCINRHNVYINGITY 655

Query: 662  RP-SFSEGTDLFSFFRDVGLKILSNAKIKKPVDCSH------RSPE-----YSTAMGAGG 709
             P S +   D++SF  D+GLK  +N+KI+KP  C          PE     +  +   G 
Sbjct: 656  TPVSSTNEKDMYSFLEDMGLKAFTNSKIRKPKMCPQLQQYEMHGPEGLRVGFYESDVMGR 715

Query: 710  GHPEAFESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFC 769
            GH        P        VR+YFPETW+WDL  + ++G   V VTVPD ITEWKA +FC
Sbjct: 716  GHARLVHVEEP----HTETVRKYFPETWIWDLVVVNSAGVAEVGVTVPDTITEWKAGAFC 771

Query: 770  TSQSRGFGLSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKS 829
             S+  G G+S T  L AF+PFFV+LT+PYSV+RGE+F L AT+ NYL  CIRV   L  S
Sbjct: 772  LSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEAS 831

Query: 830  HEYQLESWADSQTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVP 889
              +        Q   C+CA+  +T  W +T   LG++NFT+S + L+S E CG +   VP
Sbjct: 832  PAFLAVPVEKEQAPHCICANGRQTVSWAVTPKSLGNVNFTVSAEALESQELCGTEVPSVP 891

Query: 890  QKGRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVL 949
            + GR DT+IKP+LV+PEG+  E T +SLLCP G   SE +SL+LP ++V +S +A V+VL
Sbjct: 892  EHGRKDTVIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVL 951

Query: 950  GDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIG 1009
            GDI+G+A+QN   L+QMP GCGEQNMVLFAP IYVL YL +   LT EI+S+A+G+L  G
Sbjct: 952  GDILGSAMQNTQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIKSKAIGYLNTG 1011

Query: 1010 YQKELMYKHSNGSYSAFGERDG--NGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMA 1067
            YQ++L YKH +GSYS FGER G   GNTWLTAFV K F QA+ +IFID  +I  AL W++
Sbjct: 1012 YQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLS 1071

Query: 1068 GNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNS 1127
              Q  +GC+ + G+LL+ A+KGGV+DEV+L+AY+T ALLE+   V  P+V   L CL+++
Sbjct: 1072 QRQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLTVTHPVVRNALFCLESA 1131

Query: 1128 ATST------TNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSS 1181
              +       +++YT+ALLAY F+LAG  D R  +LK L+++A+    S++W +   P +
Sbjct: 1132 WKTAQEGDHGSHVYTKALLAYAFALAGNQDKRKEVLKSLNEEAVKKDNSVHWERPQKPKA 1191

Query: 1182 NASPWSEPAA--VDVELTAYALLAQLT-KPSLTQKEIAKATSIVAWLAKQRNAYGGFSST 1238
                + EP A   +VE+T+Y LLA LT +P+ T +++  AT+IV W+ KQ+NA GGFSST
Sbjct: 1192 PVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNIVKWITKQQNAQGGFSST 1251

Query: 1239 QDTVVALQALAKY-ATTAYMPSEEINLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGM 1297
            QDTVVAL AL+KY A T     +   + ++S+  F   F + + NRL+ QQ +LP +PG 
Sbjct: 1252 QDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSSKFQVDNNNRLLLQQVSLPELPGE 1311

Query: 1298 YTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVG 1357
            Y+++ +G+GCVY+QT L+YNILP      F+L V+     C++P +  S  +++  SY G
Sbjct: 1312 YSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPQTCDEPKAHTSFQISLSVSYTG 1371

Query: 1358 SRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTF 1417
            SRS+SNMAIV+VKM+SGF P++ T ++L +   V + E  ++ + IYLD++   T +  F
Sbjct: 1372 SRSASNMAIVDVKMVSGFIPLKPTVKMLERSNHVSRTEVSSNHVLIYLDKVSNQTLSLFF 1431

Query: 1418 TISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDPC 1453
            T+ Q V V +LKPA +KVYDYY  DE A  +Y+ PC
Sbjct: 1432 TVLQDVPVRDLKPAIVKVYDYYETDEFAIAEYNAPC 1467


>gi|162809334 pregnancy-zone protein [Homo sapiens]
          Length = 1482

 Score =  984 bits (2545), Expect = 0.0
 Identities = 564/1487 (37%), Positives = 851/1487 (57%), Gaps = 64/1487 (4%)

Query: 5    LLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQK 64
            LLL +L+ S + + E P Y+V +P+ L+  + +K C+ LS     V  + +LE+  + + 
Sbjct: 13   LLLILLSASDSNSTE-PQYMVLVPSLLHTEAPKKGCVLLSHLNETVTVSASLESGRENRS 71

Query: 65   LLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFV 124
            L      +K   HC+SF +P     + EVA + +   G    F ++  VL+    +  FV
Sbjct: 72   LFTDLVAEKDLFHCVSFTLPR-ISASSEVAFLSIQIKGPTQDFRKRNTVLVLNTQSLVFV 130

Query: 125  QTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLS 184
            QTDKP+Y PGQ V FR+V++D NF P N+   ++ L++P  NRIAQW  +  E GI  LS
Sbjct: 131  QTDKPMYKPGQTVRFRVVSVDENFRPRNELIPLIYLENPRRNRIAQWQSLKLEAGINQLS 190

Query: 185  FQLAPEAMLGTYTVAV---AEGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKIC 241
            F L+ E + G+Y V V   + G+    F+VEE+VLPKF+V+V  PK +S + E   + +C
Sbjct: 191  FPLSSEPIQGSYRVVVQTESGGRIQHPFTVEEFVLPKFEVKVQVPKIISIMDEKVNITVC 250

Query: 242  CRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATF 301
              YTYGKP+ G   VS+C+K +      V      + C   S Q +  GC +  V     
Sbjct: 251  GEYTYGKPVPGLATVSLCRKLS-----RVLNCDKQEVCEEFSQQLNSNGCITQQVHTKML 305

Query: 302  DLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGKI 361
             +    +  ++ + A + EEGT +E  A +   I+  +  + F    + +    PF  ++
Sbjct: 306  QITNTGFEMKLRVEARIREEGTDLEVTANRISEITNIVSKLKFVKVDSHFRQGIPFFAQV 365

Query: 362  RVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQM 421
             +       + N L F+ +   N   N T  T+  GLA F++ T+  +   + +      
Sbjct: 366  LLVDGKGVPIPNKLFFISVNDANYYSNAT--TNEQGLAQFSINTTSISVNKLFVRVFTVH 423

Query: 422  EDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADA 481
             +L ++   V   +Q A       +S + S++ +  + G L CG  + +   Y ++    
Sbjct: 424  PNLCFHYSWVAEDHQGAQHTANRVFSLSGSYIHLEPVAGTLPCGHTETITAHYTLNRQAM 483

Query: 482  SPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFP 541
                E+SF Y ++ KG +V  G   L  +   +K SF+LS    S +AP   + I+AI P
Sbjct: 484  GELSELSFHYLIMAKGVIVRSGTHTLPVESGDMKGSFALSFPVESDVAPIARMFIFAILP 543

Query: 542  SGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLL 601
             G VV D  +F +E C  N+V L FSP+Q  P +   LQ+ AAP SLCALRAVD+SVLL+
Sbjct: 544  DGEVVGDSEKFEIENCLANKVDLSFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLM 603

Query: 602  RPDRELSNRSVYGMFPFW-YGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQ---- 656
            +P+ ELS  SVY +       ++P  V + ++                  QGH  +    
Sbjct: 604  KPEAELSVSSVYNLLTVKDLTNFPDNVDQQEE-----------------EQGHCPRPFFI 646

Query: 657  -RSIIWRPSFSEGTDLFSFFRDVGLKILSNAKIKKPVDCSHRSPEYSTAMG-----AGGG 710
                I+ P  S   D++SF + +GLK+ +N+KI+KP  CS      + A+G     AG G
Sbjct: 647  HNGAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKPKSCSVIPSVSAGAVGQGYYGAGLG 706

Query: 711  ---HPEAFESST----PLHQAEDS-----QVRQYFPETWLWDLFPIGNSGKEAVHVTVPD 758
                P   +  T    PL+  + S      VR YFPETW+W+L  + +SG   V VTVPD
Sbjct: 707  VVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSYFPETWIWELVAVNSSGVAEVGVTVPD 766

Query: 759  AITEWKAMSFCTSQSRGFGLSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKD 818
             ITEWKA +FC S+  G G+S T  L AF+PFFV+LT+PYSV+RGE F L AT+ NYL  
Sbjct: 767  TITEWKAGAFCLSEDAGLGISSTASLRAFQPFFVELTMPYSVIRGEVFTLKATVLNYLPK 826

Query: 819  CIRVQTDLAKSHEYQLESWADSQTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSN 878
            CIRV   L  S  +        + S C+C +E +T  W +T   LG++NF++S + + S 
Sbjct: 827  CIRVSVQLKASPAFLASQNTKGEESYCICGNERQTLSWTVTPKTLGNVNFSVSAEAMQSL 886

Query: 879  EPCGGQKGFVPQKGRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIV 938
            E CG +   VP+  R DT+IK +LV+ EG+  EKT SS+ C  G   SE +SL+LP ++V
Sbjct: 887  ELCGNEVVEVPEIKRKDTVIKTLLVEAEGIEQEKTFSSMTCASGANVSEQLSLKLPSNVV 946

Query: 939  PDSTKAYVTVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEI 998
             +S +A  +VLGDI+G+A+QN+  L+QMP GCGEQNMVLFAP IYVL YL +   LT+EI
Sbjct: 947  KESARASFSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEI 1006

Query: 999  RSRAVGFLEIGYQKELMYKHSNGSYSAFGERDG--NGNTWLTAFVTKCFGQAQKFIFIDP 1056
            +++AVG+L  GYQ++L YKH +GSYS FGER G   GNTWLTAFV K F QA+ +IFID 
Sbjct: 1007 KAKAVGYLITGYQRQLNYKHQDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDE 1066

Query: 1057 KNIQDALKWMAGNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPM 1116
             +I  +L W++  Q  +GC+ + G+LL+ A+KGGV+DE +L+AYVT ALLE+   V +P+
Sbjct: 1067 AHITQSLTWLSQMQKDNGCFRSSGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPI 1126

Query: 1117 VSQGLRCLKNS------ATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGES 1170
            V   L CL+++       T  +++YT+ALLAY FSL G+ +    +L  LD++A+     
Sbjct: 1127 VRNALFCLESAWNVAKEGTHGSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNL 1186

Query: 1171 IYWS--QKPTPSSNASPWSEPAAVDVELTAYALLAQLT-KPSLTQKEIAKATSIVAWLAK 1227
            ++W   Q+P         ++  + +VE+T+Y LLA LT +P+ T  ++  AT+IV W+ K
Sbjct: 1187 VHWERPQRPKAPVGHLYQTQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMK 1246

Query: 1228 QRNAYGGFSSTQDTVVALQALAKYATTAYMPSEE-INLVVKSTENFQRTFNIQSVNRLVF 1286
            Q+NA GGFSSTQDTVVAL AL++Y    +  +E+   + V+ ++ F   F + + N L+ 
Sbjct: 1247 QQNAQGGFSSTQDTVVALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLL 1306

Query: 1287 QQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRS 1346
            QQ +LP +PG Y +  +G+ CVY+QT ++YNILP      F+L V+     C+   +  S
Sbjct: 1307 QQISLPELPGEYVITVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTS 1366

Query: 1347 LTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLD 1406
              +++  SY G+R +SNM IV+VKM+SGF P++ T ++L +   V + E   + + IY++
Sbjct: 1367 FQISLTISYTGNRPASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVE 1426

Query: 1407 ELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDPC 1453
            ++   T +++F + Q + V +LKPA +KVYDYY  DE    +Y  PC
Sbjct: 1427 QVTNQTLSFSFMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAPC 1473


>gi|239744583 PREDICTED: ovostatin 2 [Homo sapiens]
          Length = 1394

 Score =  714 bits (1842), Expect = 0.0
 Identities = 465/1390 (33%), Positives = 710/1390 (51%), Gaps = 78/1390 (5%)

Query: 23   YLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQKLLEYSGLKKRHLHCISFL 82
            Y++ +P+ L   S+ K C  L      V  TV+L   +   K+ E +   +    CISF 
Sbjct: 13   YVLLIPSVLQEGSLDKACAQLFNLTESVVLTVSLNYGEVQTKIFEENVTGENFFKCISFE 72

Query: 83   VPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFVQTDKPLYTPGQQVYFRIV 142
            VP     ++ +A I  S  G  ++ EE++ V I+ + N  FVQTDKP Y PGQ+    I 
Sbjct: 73   VPQAR--SDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIA 130

Query: 143  TMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSFQLAPEAMLGTYTVAVAE 202
                +       Y  + L+DP +NRI QW  V   + I  LSFQL  E M G Y + V  
Sbjct: 131  QFFLDTYTFT--YPNITLKDPQNNRIFQWQNVTSFRNITQLSFQLISEPMFGDYWIVVKR 188

Query: 203  GK---TFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKICCRYTYGKPMLGAVQVSVC 259
                     F+V+ YVLPKF+V V  P+ ++   + F V +C +YT+G+P+ G  Q+ VC
Sbjct: 189  NSRKTVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYTFGQPVQGKTQIRVC 248

Query: 260  QKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATFDLIGYAYSHQINIVATVV 319
            ++   Y+      +   + C     Q +  GC S  V+   F L         ++   V 
Sbjct: 249  RE---YFSSSNCEKNDNEICEQFIAQLEN-GCVSQIVNTKVFQLYRSGLFMTFHVAVIVT 304

Query: 320  EEGTG---VEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDSFLKNHLV 376
            E GTG   ++ +   +++I+  +G++ FE+   FY     + G ++    ++  + N L+
Sbjct: 305  EFGTGNYCMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNVPMVNKLL 364

Query: 377  FLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQ 436
             L +   N  F     TD NG A F+++TS     + +L+  +      Y P  +   Y 
Sbjct: 365  QLEL---NDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPKSCYLPSWLTPQYL 421

Query: 437  NAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGK 496
            +A+  +  FYS T SFL I      L+C   + V V Y ++      D  + F +YL+  
Sbjct: 422  DAHFLVSRFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKF-FYLVSL 480

Query: 497  GSLVMEGQKHLNSKK--KGLKASFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSV 554
                   Q  ++S         +FS  L+ ++ LAP   L +Y + PSG +VAD ++F V
Sbjct: 481  SHDSGNFQHRISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQV 540

Query: 555  EMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRSVYG 614
            + CF ++V++ FS  Q LPG+   L LQAAP   CAL AVD +VLLL+ +++LS  SVY 
Sbjct: 541  DKCFKHKVNIKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYN 600

Query: 615  MFPFW--YGHYPYQV----AEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEG 668
            M P    YG++ + +     + D C               +PQ       + + P  + G
Sbjct: 601  MVPSIEPYGYFYHGLNLDDGKEDPC---------------IPQRDMFYNGLYYTPVSNYG 645

Query: 669  T-DLFSFFRDVGLKILSNAKIKKPVDCSHR------SPEYSTAMGAGGGH--PEAF---- 715
              D+++  R++GLK+ +N   +KP  C          P Y      G  H  P       
Sbjct: 646  DGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIACRG 705

Query: 716  ESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRG 775
            E++  + QA    VR  FPETW+WDL  + +SG   +   +PD IT+W+A  FC +   G
Sbjct: 706  ENADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVG 765

Query: 776  FGLSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQ-- 833
            FG+S T  L   +PFF+++  P+SVV+ E F L    F+YL  C+ +   + +S  Y+  
Sbjct: 766  FGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEAN 825

Query: 834  LESWADSQTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQK-G 892
            + +W  +  S  + A   KT+ W I   KLG +N T+  +   S+  C  + G   QK  
Sbjct: 826  INTWKING-SEVIQAGGRKTNIWTIIPKKLGKVNITVVAESKQSSA-CPNE-GMEQQKLN 882

Query: 893  RSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVLGDI 952
              DT++K  LV+PEG+  E+T S L+C +G  AS+   L+LP D+V  S + + TV+GDI
Sbjct: 883  WKDTVVKSFLVEPEGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDI 942

Query: 953  MGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIGYQK 1012
            +G A+QNL  ++QMP G GEQN  L A   YVL YL+    LTEE++S+A   L  GYQ+
Sbjct: 943  LGLAMQNLV-VLQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLLSNGYQR 1001

Query: 1013 ELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLP 1072
            +L +K+S+GSYS F +++  G+ WL+A   K   + +KF+FID    +  L W++  Q  
Sbjct: 1002 QLSFKNSDGSYSVFWQQNQKGSIWLSALTFKTLERMKKFVFIDENVQKQTLIWLSSQQKT 1061

Query: 1073 SGCYANVGNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNSATS-T 1131
            SGC+ N G L + A +GG ++++SLTAYV     E G +   P +   L CL+ +  S  
Sbjct: 1062 SGCFKNDGQLFNHAWEGGDEEDISLTAYVVGMFFEAGLNSTFPALRNALFCLEAALDSGV 1121

Query: 1132 TNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSSNASPWSEPAA 1191
            TN Y  A+LAY F+LAG+      LL+ LDQ A      IYW ++  P +   P   P A
Sbjct: 1122 TNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYWERERKPKTEEFPSFIPWA 1181

Query: 1192 --VDVELTAYALLAQLTK--PSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDTVVALQA 1247
                 E + Y LLA +++  P LT      A+ IV WLA+Q N++GGFSS Q   V L  
Sbjct: 1182 PSAQTEKSCYVLLAVISRKIPDLTY-----ASKIVQWLAQQMNSHGGFSSNQVINVGLIL 1236

Query: 1248 LAKYATTAYMPSEEINLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGMYTLEASGQGC 1307
            +A           +  +   S  + +  FN    NRL+ Q+  +   PG YT++  G+GC
Sbjct: 1237 IAICGEEGLFSKNQNTVTFSSEGSSEIQFN--GHNRLLVQRSEVTQAPGQYTVDVEGRGC 1294

Query: 1308 VYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIV 1367
             ++Q  L+YN+L P     FSLS+EI K       S     LT++  Y G R+ S+M ++
Sbjct: 1295 TFIQATLKYNVLLPKKASGFSLSLEIVK-----NYSLTVFDLTVNLKYTGIRNKSSMVVI 1349

Query: 1368 EVKMLSGFSP 1377
            +VKMLSGF+P
Sbjct: 1350 DVKMLSGFTP 1359


>gi|169204289 PREDICTED: ovostatin [Homo sapiens]
          Length = 1353

 Score =  686 bits (1769), Expect = 0.0
 Identities = 447/1344 (33%), Positives = 683/1344 (50%), Gaps = 82/1344 (6%)

Query: 76   LHCISFLVPPPAGGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFVQTDKPLYTPGQ 135
            L   S L   P   ++ +A I  S  G  ++ EE++ V I+ + N  FVQTDKP Y PGQ
Sbjct: 15   LMIFSILNVVPQARSDPLAFITFSAKGATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQ 74

Query: 136  QVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSFQLAPEAMLGT 195
            +    I     +       Y  + L+DP +NRI Q   V   + I  LSFQL  E M G 
Sbjct: 75   KDVNGIAQFFLDTYTFT--YPNITLKDPQNNRIFQRQNVTSFRNITQLSFQLISEPMFGD 132

Query: 196  YTVAVAEGK---TFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKICCRYTYGKPMLG 252
            Y + V           F+V+ YVLPKF+V V  P+ ++   + F V +C +Y +G+P+ G
Sbjct: 133  YWIVVKRNSRETVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAKYNFGQPVQG 192

Query: 253  AVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATFDLIGYAYSHQI 312
              Q+ VC++  +    E    ++   C     Q +  GC S  V+   F L         
Sbjct: 193  ETQIRVCREYFSSSNCEKNENEI---CEQFIAQLEN-GCVSQIVNTKVFQLYRSGLFMTF 248

Query: 313  NIVATVVEEGTG---VEANATQNIYISPQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDS 369
            ++   V E GTG   ++ +   +++I+  +G++ FE+   FY     + G ++    ++ 
Sbjct: 249  HVAVIVTESGTGNYFMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGTLKFSDPNNV 308

Query: 370  FLKNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPE 429
             + N L+ L +   N  F     TD NG A F+++TS     + +L+  +   +  Y P 
Sbjct: 309  PMVNKLLQLEL---NDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPS 365

Query: 430  QVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISF 489
             +   Y +A+  +  FYS T SFL I      L+C Q + V V Y ++      D  + F
Sbjct: 366  WLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNQQKVVTVHYSLNSEAYEDDSNVKF 425

Query: 490  SYYLIGKGSLVMEGQKHLNSKK--KGLKASFSLSLTFTSRLAPDPSLVIYAIFPSGGVVA 547
             +YL+         Q  ++S         +FS  ++ ++ LAP   L +Y + PSG +VA
Sbjct: 426  -FYLVSLSHDSGNFQHRISSSPIYTAWNGNFSFPISISADLAPAAVLFVYTLHPSGEIVA 484

Query: 548  DKIQFSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLLRPDREL 607
            D ++F V+ CF ++V++ FS  Q LPG+   L LQAAP   CALRAVD +VLLL+ +++L
Sbjct: 485  DSVRFQVDKCFKHKVNIKFSNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQL 544

Query: 608  SNRSVYGMFPFW--YGHYPYQV----AEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIW 661
            S  SVY M P    YG++ + +     + D C               +PQ       + +
Sbjct: 545  SAESVYNMVPSIEPYGYFYHGLNLDDGKEDPC---------------IPQRDMFYNGLYY 589

Query: 662  RPSFSEGT-DLFSFFRDVGLKILSNAKIKKPVDC--SHRSP----------EYSTAMGAG 708
             P  + G  D+++  R++GLK+ +N   +KP  C    R P           Y       
Sbjct: 590  TPVSNYGDGDIYNIVRNMGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMRSVP 649

Query: 709  GGHPEAFESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSF 768
                   E++  + QA    VR  FPETW+WDL  + +SG   +   +PD IT+W+A  F
Sbjct: 650  SRIACRGENADYVEQAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGF 709

Query: 769  CTSQSRGFGLSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAK 828
            C +   GFG+S T  L   +PFF+++  P+SVV+ E F L   +F+Y   C+ +   + +
Sbjct: 710  CVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEE 769

Query: 829  SHEYQLESWA-DSQTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGF 887
            S  Y+          S  + A   KT+ W I   KLG +N T+  +   S+  C  + G 
Sbjct: 770  SQNYEANIHTLKINGSEVIQAGGRKTNVWTIIPKKLGKVNITVVAESKQSSA-CPNE-GM 827

Query: 888  VPQK-GRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYV 946
              QK    DT+++  LV+PEG+  E+T S L+C +G  AS+   L+LP D+V  S + + 
Sbjct: 828  EQQKLNWKDTVVQSFLVEPEGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFF 887

Query: 947  TVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFL 1006
            TV+GDI+G ALQNL  ++QMP G GEQN  L A   YVL YL+    LTEE++S+A   L
Sbjct: 888  TVVGDILGLALQNLV-VLQMPYGSGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLL 946

Query: 1007 EIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWM 1066
              GYQ++L +K+S+GSYS F ++   G+  L+A   K   + +K++FID    +  L W+
Sbjct: 947  SNGYQRQLSFKNSDGSYSVFWQQSQKGSIXLSALTFKTLERMKKYVFIDENVQKQTLIWL 1006

Query: 1067 AGNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKN 1126
            +  Q  SGC+ N G L + A +GG ++++SLTAYV     E G +   P +   L CL+ 
Sbjct: 1007 SSQQKTSGCFKNDGQLFNHAWEGGDEEDISLTAYVVGMFFEAGLNFTFPALRNALFCLEA 1066

Query: 1127 SATS-TTNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSSNASP 1185
            +  S  TN Y  A+LAY F+LAG+      LL+ LDQ A      IYW ++  P +   P
Sbjct: 1067 ALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSAPKLNNVIYWERERKPKTEEFP 1126

Query: 1186 WSEPAA--VDVELTAYALLAQLTK--PSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDT 1241
               P A     E + Y LLA +++  P LT      A+ IV WLA++ N++GGFSS Q  
Sbjct: 1127 SFIPWAPSAQTEKSCYVLLAVISRKIPDLTY-----ASKIVQWLAQRMNSHGGFSSNQVI 1181

Query: 1242 VVAL--------QALAKYATTAYMPSEEINLVVKSTENFQRTFNIQSVNRLVFQQDTLPN 1293
             V L        Q LA+     +  S++ N V  S+E     F +   NRL+ Q+  +  
Sbjct: 1182 NVGLILIAICLMQKLARGEEGLF--SKDQNTVTFSSEGSSEIFQVNGHNRLLVQRSEVTQ 1239

Query: 1294 VPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPRSLTLTIHT 1353
             PG YT++  G GC ++Q  L+YN+L P     FSLS+EI K       S  +  LT+  
Sbjct: 1240 APGEYTVDVEGHGCTFIQATLKYNVLLPKKASGFSLSLEIVK-----NYSSTAFDLTVTL 1294

Query: 1354 SYVGSRSSSNMAIVEVKMLSGFSP 1377
             Y G R+ S+M +++VKMLSGF+P
Sbjct: 1295 KYTGIRNKSSMVVIDVKMLSGFTP 1318


>gi|115529484 CD109 antigen isoform 1 precursor [Homo sapiens]
          Length = 1445

 Score =  522 bits (1344), Expect = e-147
 Identities = 419/1501 (27%), Positives = 710/1501 (47%), Gaps = 184/1501 (12%)

Query: 10   LALSPAIAEELPNYLVTLPARLNFPSVQKVCLDL---SPGYSDVKFTVTLETKDKTQKLL 66
            LA++P      P +LVT P  +       + ++L    P    VK  +     + T  +L
Sbjct: 20   LAVAPG-----PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVL 74

Query: 67   EYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSG-VGNNISFEEKKKVLIQRQGNGTFVQ 125
            E  G+ ++       L   P    +E+  +RV+G   + I F    ++  + +    F+Q
Sbjct: 75   EAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQ 134

Query: 126  TDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSF 185
            TDK LY P Q+V FRIVT+ S+F P     +++ ++DP SN I QWL    + G++  +F
Sbjct: 135  TDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGVISKTF 193

Query: 186  QLAPEAMLGTYTVAVA--EGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKICCR 243
            QL+   +LG +++ V   +   + +F V EYVLPKF+V +  P   S   +     I  +
Sbjct: 194  QLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAK 253

Query: 244  YTYGKPMLGAVQVSVC-------QKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPV 296
            YTYGKP+ G V ++         +K  T  ++             +    D +   S  +
Sbjct: 254  YTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYL 313

Query: 297  DMATFDLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFP 356
            D+++           + I+ TV E  TG+  N + N++       + F D +    P+  
Sbjct: 314  DLSS--------PGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLN 365

Query: 357  FSGKIRVRGHDDSFL-----KNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGT 411
            F+  ++V   D + L     +N++V  V   T   + +     N+G     +E       
Sbjct: 366  FTATVKVTRADGNQLTLEERRNNVVITV---TQRNYTEYWSGSNSGNQK--MEAVQKINY 420

Query: 412  DVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRL------------- 458
             V   G F++E         P    ++ L L+ ++  ++S + +H L             
Sbjct: 421  TVPQSGTFKIE--------FPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKT 472

Query: 459  -NGPLKCGQPQEVLVDYYIDPADASPDQEIS-FSYYLIGKGSLVMEGQKHLNSKKKGLKA 516
             +  +K G P E++V         S ++ +   SY ++ +G LV  G+++          
Sbjct: 473  RDENIKVGSPFELVV---------SGNKRLKELSYMVVSRGQLVAVGKQN---------- 513

Query: 517  SFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAE 576
            S   SLT  +   P   +++Y I   G +++D ++  V++ F N++ L +S  +  P  +
Sbjct: 514  STMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEK 573

Query: 577  VELQLQAA-PGSLCALRAVDESVLLLRPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPV 635
            V L++    P S+  + AVD+SV L+    +++  +V            +++  Y+    
Sbjct: 574  VSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVV-----------HELELYNTGYY 622

Query: 636  SGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGTDLFSFFRDVGLKILSNAKIKKP-VDC 694
             G +                              + F+ F++ GL +L++A + K  +D 
Sbjct: 623  LGMF-----------------------------MNSFAVFQECGLWVLTDANLTKDYIDG 653

Query: 695  SHRSPEYSTA-MGAGGGHPEAFESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVH 753
             + + EY+   M    GH       +         VR++FPETW+W    +G    +   
Sbjct: 654  VYDNAEYAERFMEENEGHIVDIHDFS---LGSSPHVRKHFPETWIWLDTNMGYRIYQEFE 710

Query: 754  VTVPDAITEWKAMSFCTSQSRGFGLSPT-VGLTAFKPFFVDLTLPYSVVRGESFRLTATI 812
            VTVPD+IT W A  F  S+  G GL+ T V L AF+PFF+ L LPYSV+RGE F L  TI
Sbjct: 711  VTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITI 770

Query: 813  FNYLKDCIRVQTDLAKSHEYQLESWADS------QTSSCLCADEAKTHHWNITAVKLGHI 866
            FNYLKD   V+  + KS ++ +   ++       Q +  + +++  T  + I    LG I
Sbjct: 771  FNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEI 830

Query: 867  NFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKPVLVKPEGVLVEKTHSSLL-CPKGKVA 925
              T++                      SD + + +LVK EG+    + S LL     ++ 
Sbjct: 831  PITVTAL----------------SPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQ 874

Query: 926  S--ESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIY 983
            S  +++S   P + V  S +  +T +GD++G ++  L  L++MP GCGEQNM+ FAP IY
Sbjct: 875  STLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIY 934

Query: 984  VLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTK 1043
            +L YL K   LT+ ++ +A+ F+  GYQ+EL+Y+  +GS+SAFG  D +G+TWL+AFV +
Sbjct: 935  ILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLR 994

Query: 1044 CFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTA 1103
            CF +A  +I ID   +     W+ G+Q  +G + + G ++H+ ++GG    V+LTAY+  
Sbjct: 995  CFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVT 1054

Query: 1104 ALLEMGKDVDDPMVSQGLRCLKNS-ATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQ 1162
            +LL   K   +  V + +  L++  +   ++ YT AL+ Y  S  G    +   L  L  
Sbjct: 1055 SLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKE-ALNMLTW 1113

Query: 1163 QAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATSIV 1222
            +A   G   +W    +  S++  W +P ++D+E+ AYALL+        Q + ++   I+
Sbjct: 1114 RAEQEGGMQFWVSSESKLSDS--W-QPRSLDIEVAAYALLSH-----FLQFQTSEGIPIM 1165

Query: 1223 AWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVVKSTENFQRT---FNIQ 1279
             WL++QRN+ GGF+STQDT VAL+AL+++A  A M +E  N+ V  T     +   F I 
Sbjct: 1166 RWLSRQRNSLGGFASTQDTTVALKALSEFA--ALMNTERTNIQVTVTGPSSPSPVKFLID 1223

Query: 1280 SVNRLVFQQDTLPNV-PGMYTLEASGQGCVYVQTVLRYNILPP---------TNMKTFSL 1329
            + NRL+ Q   L  V P    + A+G G    Q  + YN+             N + F L
Sbjct: 1224 THNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDL 1283

Query: 1330 SVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQP 1389
             V +     E       + L + TS+ G    S MA++EV +LSGF  M  +  + L + 
Sbjct: 1284 DVAVK----ENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGF--MVPSEAISLSE- 1335

Query: 1390 LVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQY 1449
             VKKVE+    LN+YLD + +          ++  V+N + A++ + DYY P  QA   Y
Sbjct: 1336 TVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSY 1395

Query: 1450 S 1450
            +
Sbjct: 1396 N 1396


>gi|227430301 CD109 antigen isoform 2 precursor [Homo sapiens]
          Length = 1428

 Score =  514 bits (1325), Expect = e-145
 Identities = 415/1497 (27%), Positives = 704/1497 (47%), Gaps = 193/1497 (12%)

Query: 10   LALSPAIAEELPNYLVTLPARLNFPSVQKVCLDL---SPGYSDVKFTVTLETKDKTQKLL 66
            LA++P      P +LVT P  +       + ++L    P    VK  +     + T  +L
Sbjct: 20   LAVAPG-----PRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVL 74

Query: 67   EYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSG-VGNNISFEEKKKVLIQRQGNGTFVQ 125
            E  G+ ++       L   P    +E+  +RV+G   + I F    ++  + +    F+Q
Sbjct: 75   EAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQ 134

Query: 126  TDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDLSF 185
            TDK LY P Q+V FRIVT+ S+F P     +++ ++DP SN I QWL    + G++  +F
Sbjct: 135  TDKALYKPKQEVKFRIVTLFSDFKPYKTSLNIL-IKDPKSNLIQQWLSQQSDLGVISKTF 193

Query: 186  QLAPEAMLGTYTVAVA--EGKTFGTFSVEEYVLPKFKVEVVEPKELSTVQESFLVKICCR 243
            QL+   +LG +++ V   +   + +F V EYVLPKF+V +  P   S   +     I  +
Sbjct: 194  QLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAK 253

Query: 244  YTYGKPMLGAVQVSVC-------QKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPV 296
            YTYGKP+ G V ++         +K  T  ++             +    D +   S  +
Sbjct: 254  YTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYL 313

Query: 297  DMATFDLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMTFEDTSNFYHPNFP 356
            D+++           + I+ TV E  TG+  N + N++       + F D +    P+  
Sbjct: 314  DLSS--------PGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLN 365

Query: 357  FSGKIRVRGHDDSFL-----KNHLVFLVIYGTNGTFNQTLVTDNNGLAPFTLETSGWNGT 411
            F+  ++V   D + L     +N++V  V   T   + +     N+G     +E       
Sbjct: 366  FTATVKVTRADGNQLTLEERRNNVVITV---TQRNYTEYWSGSNSGNQK--MEAVQKINY 420

Query: 412  DVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRL------------- 458
             V   G F++E         P    ++ L L+ ++  ++S + +H L             
Sbjct: 421  TVPQSGTFKIE--------FPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKT 472

Query: 459  -NGPLKCGQPQEVLVDYYIDPADASPDQEIS-FSYYLIGKGSLVMEGQKHLNSKKKGLKA 516
             +  +K G P E++V         S ++ +   SY ++ +G LV  G+++          
Sbjct: 473  RDENIKVGSPFELVV---------SGNKRLKELSYMVVSRGQLVAVGKQN---------- 513

Query: 517  SFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSVEMCFDNQVSLGFSPSQQLPGAE 576
            S   SLT  +   P   +++Y I   G +++D ++  V++ F N++ L +S  +  P  +
Sbjct: 514  STMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEK 573

Query: 577  VELQLQAA-PGSLCALRAVDESVLLLRPDRELSNRSVYGMFPFWYGHYPYQVAEYDQCPV 635
            V L++    P S+  + AVD+SV L+    +++  +V            +++  Y+    
Sbjct: 574  VSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVV-----------HELELYNTGYY 622

Query: 636  SGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGTDLFSFFRDVGLKILSNAKIKKP-VDC 694
             G +                              + F+ F++ GL +L++A + K  +D 
Sbjct: 623  LGMF-----------------------------MNSFAVFQECGLWVLTDANLTKDYIDG 653

Query: 695  SHRSPEYSTA-MGAGGGHPEAFESSTPLHQAEDSQVRQYFPETWLWDLFPIGNSGKEAVH 753
             + + EY+   M    GH       +         VR++FPETW+W    +G    +   
Sbjct: 654  VYDNAEYAERFMEENEGHIVDIHDFS---LGSSPHVRKHFPETWIWLDTNMGYRIYQEFE 710

Query: 754  VTVPDAITEWKAMSFCTSQSRGFGLSPT-VGLTAFKPFFVDLTLPYSVVRGESFRLTATI 812
            VTVPD+IT W A  F  S+  G GL+ T V L AF+PFF+ L LPYSV+RGE F L  TI
Sbjct: 711  VTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITI 770

Query: 813  FNYLKDCIRVQTDLAKSHEYQLESWADS------QTSSCLCADEAKTHHWNITAVKLGHI 866
            FNYLKD   V+  + KS ++ +   ++       Q +  + +++  T  + I    LG I
Sbjct: 771  FNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEI 830

Query: 867  NFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKPVLVKPEGVLVEKTHSSLL-CPKGKVA 925
              T++                      SD + + +LVK EG+    + S LL     ++ 
Sbjct: 831  PITVTAL----------------SPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQ 874

Query: 926  S--ESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIY 983
            S  +++S   P + V  S +  +T +GD++G ++  L  L++MP GCGEQNM+ FAP IY
Sbjct: 875  STLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIY 934

Query: 984  VLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTK 1043
            +L YL K   LT+ ++ +A+ F+  GYQ+EL+Y+  +GS+SAFG  D +G+TWL+AFV +
Sbjct: 935  ILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLR 994

Query: 1044 CFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTA 1103
            CF +A  +I ID   +     W+ G+Q  +G + + G ++H+ ++GG    V+LTAY+  
Sbjct: 995  CFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVT 1054

Query: 1104 ALLEMGKDVDDPMVSQGLRCLKNS-ATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQ 1162
            +LL   K   +  V + +  L++  +   ++ YT AL+ Y  S  G    +   L  L  
Sbjct: 1055 SLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKE-ALNMLTW 1113

Query: 1163 QAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATSIV 1222
            +A   G   +W    +  S++  W +P ++D+E+ AYALL+        Q + ++   I+
Sbjct: 1114 RAEQEGGMQFWVSSESKLSDS--W-QPRSLDIEVAAYALLSH-----FLQFQTSEGIPIM 1165

Query: 1223 AWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVVKSTENFQRTFNIQSVN 1282
             WL++QRN+ GGF+STQDT VAL+AL+++A  A M +E  N+ V  T          S +
Sbjct: 1166 RWLSRQRNSLGGFASTQDTTVALKALSEFA--ALMNTERTNIQVTVT-------GPSSPS 1216

Query: 1283 RLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPP---------TNMKTFSLSVEI 1333
             L   Q T  N+       A+G G    Q  + YN+             N + F L V +
Sbjct: 1217 PLAVVQPTAVNI------SANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAV 1270

Query: 1334 GKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLLLQQPLVKK 1393
                 E       + L + TS+ G    S MA++EV +LSGF  M  +  + L +  VKK
Sbjct: 1271 K----ENKDDLNHVDLNVCTSFSGP-GRSGMALMEVNLLSGF--MVPSEAISLSE-TVKK 1322

Query: 1394 VEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYS 1450
            VE+    LN+YLD + +          ++  V+N + A++ + DYY P  QA   Y+
Sbjct: 1323 VEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYN 1379


>gi|227430303 CD109 antigen isoform 3 precursor [Homo sapiens]
          Length = 1368

 Score =  474 bits (1221), Expect = e-133
 Identities = 377/1345 (28%), Positives = 637/1345 (47%), Gaps = 174/1345 (12%)

Query: 162  DPNSNRIAQWLEVVPEQGIVDLSFQLAPEAMLGTYTVAVA--EGKTFGTFSVEEYVLPKF 219
            DP SN I QWL    + G++  +FQL+   +LG +++ V   +   + +F V EYVLPKF
Sbjct: 93   DPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKF 152

Query: 220  KVEVVEPKELSTVQESFLVKICCRYTYGKPMLGAVQVSVC-------QKANTYWYREVER 272
            +V +  P   S   +     I  +YTYGKP+ G V ++         +K  T  ++    
Sbjct: 153  EVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGS 212

Query: 273  EQLPDKCRNLSGQTDKTGCFSAPVDMATFDLIGYAYSHQINIVATVVEEGTGVEANATQN 332
                     +    D +   S  +D+++           + I+ TV E  TG+  N + N
Sbjct: 213  ANFSFNDEEMKNVMDSSNGLSEYLDLSS--------PGPVEILTTVTESVTGISRNVSTN 264

Query: 333  IYISPQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDSFL-----KNHLVFLVIYGTNGTF 387
            ++       + F D +    P+  F+  ++V   D + L     +N++V  V   T   +
Sbjct: 265  VFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITV---TQRNY 321

Query: 388  NQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYS 447
             +     N+G     +E        V   G F++E         P    ++ L L+ ++ 
Sbjct: 322  TEYWSGSNSGNQK--MEAVQKINYTVPQSGTFKIE--------FPILEDSSELQLKAYFL 371

Query: 448  TTRSFLGIHRL--------------NGPLKCGQPQEVLVDYYIDPADASPDQEIS-FSYY 492
             ++S + +H L              +  +K G P E++V         S ++ +   SY 
Sbjct: 372  GSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVV---------SGNKRLKELSYM 422

Query: 493  LIGKGSLVMEGQKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQF 552
            ++ +G LV  G+++          S   SLT  +   P   +++Y I   G +++D ++ 
Sbjct: 423  VVSRGQLVAVGKQN----------STMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKI 472

Query: 553  SVEMCFDNQVSLGFSPSQQLPGAEVELQLQAA-PGSLCALRAVDESVLLLRPDRELSNRS 611
             V++ F N++ L +S  +  P  +V L++    P S+  + AVD+SV L+    +++  +
Sbjct: 473  PVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMEN 532

Query: 612  VYGMFPFWYGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGTDL 671
            V            +++  Y+     G +                              + 
Sbjct: 533  VV-----------HELELYNTGYYLGMF-----------------------------MNS 552

Query: 672  FSFFRDVGLKILSNAKIKKP-VDCSHRSPEYSTA-MGAGGGHPEAFESSTPLHQAEDSQV 729
            F+ F++ GL +L++A + K  +D  + + EY+   M    GH       +         V
Sbjct: 553  FAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFS---LGSSPHV 609

Query: 730  RQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPT-VGLTAFK 788
            R++FPETW+W    +G    +   VTVPD+IT W A  F  S+  G GL+ T V L AF+
Sbjct: 610  RKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQ 669

Query: 789  PFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADS------QT 842
            PFF+ L LPYSV+RGE F L  TIFNYLKD   V+  + KS ++ +   ++       Q 
Sbjct: 670  PFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQ 729

Query: 843  SSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQKGRSDTLIKPVL 902
            +  + +++  T  + I    LG I  T++                      SD + + +L
Sbjct: 730  TLLVPSEDGATVLFPIRPTHLGEIPITVTAL----------------SPTASDAVTQMIL 773

Query: 903  VKPEGVLVEKTHSSLL-CPKGKVAS--ESVSLELPVDIVPDSTKAYVTVLGDIMGTALQN 959
            VK EG+    + S LL     ++ S  +++S   P + V  S +  +T +GD++G ++  
Sbjct: 774  VKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSING 833

Query: 960  LDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHS 1019
            L  L++MP GCGEQNM+ FAP IY+L YL K   LT+ ++ +A+ F+  GYQ+EL+Y+  
Sbjct: 834  LASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQRE 893

Query: 1020 NGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANV 1079
            +GS+SAFG  D +G+TWL+AFV +CF +A  +I ID   +     W+ G+Q  +G + + 
Sbjct: 894  DGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDP 953

Query: 1080 GNLLHTAMKGGVDDEVSLTAYVTAALLEMGKDVDDPMVSQGLRCLKNS-ATSTTNLYTQA 1138
            G ++H+ ++GG    V+LTAY+  +LL   K   +  V + +  L++  +   ++ YT A
Sbjct: 954  GRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLA 1013

Query: 1139 LLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYWSQKPTPSSNASPWSEPAAVDVELTA 1198
            L+ Y  S  G    +   L  L  +A   G   +W    +  S++  W +P ++D+E+ A
Sbjct: 1014 LITYALSSVGSPKAKE-ALNMLTWRAEQEGGMQFWVSSESKLSDS--W-QPRSLDIEVAA 1069

Query: 1199 YALLAQLTKPSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMP 1258
            YALL+        Q + ++   I+ WL++QRN+ GGF+STQDT VAL+AL+++A  A M 
Sbjct: 1070 YALLSH-----FLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFA--ALMN 1122

Query: 1259 SEEINLVVKSTENFQRT---FNIQSVNRLVFQQDTLPNV-PGMYTLEASGQGCVYVQTVL 1314
            +E  N+ V  T     +   F I + NRL+ Q   L  V P    + A+G G    Q  +
Sbjct: 1123 TERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNV 1182

Query: 1315 RYNILPP---------TNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMA 1365
             YN+             N + F L V +     E       + L + TS+ G    S MA
Sbjct: 1183 VYNVKASGSSRRRRSIQNQEAFDLDVAVK----ENKDDLNHVDLNVCTSFSGP-GRSGMA 1237

Query: 1366 IVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLV 1425
            ++EV +LSGF  M  +  + L +  VKKVE+    LN+YLD + +          ++  V
Sbjct: 1238 LMEVNLLSGF--MVPSEAISLSE-TVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKV 1294

Query: 1426 TNLKPATIKVYDYYLPDEQATIQYS 1450
            +N + A++ + DYY P  QA   Y+
Sbjct: 1295 SNTQDASVSIVDYYEPRRQAVRSYN 1319


>gi|239750255 PREDICTED: similar to ovostatin-2 [Homo sapiens]
          Length = 750

 Score =  336 bits (862), Expect = 8e-92
 Identities = 219/644 (34%), Positives = 329/644 (51%), Gaps = 45/644 (6%)

Query: 384  NGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLR 443
            N  F     TD NG A F+++TS     + +L+  +   +  Y P  +   Y +A+  + 
Sbjct: 11   NDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFLVS 70

Query: 444  PFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEG 503
             FYS T SFL I      L+C   + V V Y ++      D  + F +YL    S   + 
Sbjct: 71   RFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKF-FYLCTSDSGNFQH 129

Query: 504  QKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSVEMCFDNQVS 563
            +   +        +FS  L+ ++ LAP   L +Y + PSG +VAD ++F V+ CF ++V+
Sbjct: 130  RISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVN 189

Query: 564  LGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRSVYGMFPFW--YG 621
            + FS  Q LPG+   L LQAAP   CAL AVD +VLLL+ +++LS  SVY M P    YG
Sbjct: 190  IKFSNEQGLPGSNASLYLQAAPVLFCALGAVDGNVLLLKSEQQLSAESVYNMVPSIEPYG 249

Query: 622  HYPYQV----AEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGT-DLFSFFR 676
            ++ + +     + D C               +PQ       + + P  + G  D+++  R
Sbjct: 250  YFYHGLNLDDGKEDPC---------------IPQRDMFYNGLYYTPVSNYGDGDIYNIVR 294

Query: 677  DVGLKILSNAKIKKPVDCSHR------SPEYSTAMGAGGGH--PEAFESS-------TPL 721
            ++GLK+ +N   +KP  C          P Y      G  H  P    SS         +
Sbjct: 295  NMGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMHSVPSRIASSGIRGENADYV 354

Query: 722  HQAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPT 781
             QA    VR  FPETW+WDL  + +SG   +   +PD IT+W+A  FC +   GFG+S T
Sbjct: 355  EQAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISST 414

Query: 782  VGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQ--LESWAD 839
              L   +PFF+++  P+SVV+ E F L    F+YL  C+ +   + +S  Y+  + +W  
Sbjct: 415  TTLEVSQPFFIEIASPFSVVQNEQFDLIVNAFSYLNTCVEISVQVEESQNYEANINTW-K 473

Query: 840  SQTSSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPCGGQKGFVPQK-GRSDTLI 898
               S  + A   KT+ W I   KLG +N T+  +   S+  C  + G   QK    DT++
Sbjct: 474  INGSEVIQAGGRKTNIWTIIPKKLGKVNITVVAESKQSS-ACPNE-GMEQQKLNWKDTVV 531

Query: 899  KPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLELPVDIVPDSTKAYVTVLGDIMGTALQ 958
            K  LV+PEG+  E+T S L+C +G  AS+   L+LP D+V  S + + TV+GDI+G A+Q
Sbjct: 532  KSFLVEPEGIEKERTQSFLICTEGAKASKQGVLDLPNDVVEGSARGFFTVVGDILGLAMQ 591

Query: 959  NLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAGLLTEEIRSRA 1002
            NL  ++QMP G GEQN  L A   YVL YL+    LTEE++S+A
Sbjct: 592  NL-VVLQMPYGGGEQNAALLASDTYVLDYLKSTEQLTEEVQSKA 634


>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
            8 [Homo sapiens]
          Length = 1932

 Score =  302 bits (773), Expect = 2e-81
 Identities = 199/568 (35%), Positives = 301/568 (52%), Gaps = 50/568 (8%)

Query: 926  SESVSLELPVDIVPDSTKAYVTVLGDIMGTALQNLDGLVQMPSGCGEQNMVLFAPIIYVL 985
            SE+ +L +P   +P S +A  +++GD+MG  L +L+ L+++P GCGEQNM+ FAP ++VL
Sbjct: 1147 SEAFTLGVPHGAIPGSERATASIIGDVMGPTLNHLNNLLRLPFGCGEQNMIHFAPNVFVL 1206

Query: 986  QYLEKAGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCF 1045
            +YL+K   L+ E+      +L  GYQ++L YK  +GSYSAFGERD +G+ WLTAFV K F
Sbjct: 1207 KYLQKTQQLSPEVERETTDYLVQGYQRQLTYKRQDGSYSAFGERDASGSMWLTAFVLKSF 1266

Query: 1046 GQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVGNLLHTAMKGGVDDEVSLTAYVTAAL 1105
             QA+ FIF+DP+ +  A  W+   Q   G +  VG +L+  ++GG+   V LTAYV  AL
Sbjct: 1267 AQARSFIFVDPRELAAAKSWIIQQQQADGSFLAVGRVLNKDIQGGIHGTVPLTAYVVVAL 1326

Query: 1106 LEMGKDVDDPMVS--QGLRCLKNSATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQQ 1163
            LE G   ++   S  +    L+++A    + Y+ AL  Y  +L          L++L   
Sbjct: 1327 LETGTASEEERGSTDKARHFLESAAPLAMDPYSCALTTYALTLL-RSPAAPEALRKLRSL 1385

Query: 1164 AIISGESIYWS-------QKPTPSSNASPWSEP-AAVDVELTAYALLAQLTKPSLTQKEI 1215
            AI+     +WS        K T  S +   S+   + +VE+TAYALL           ++
Sbjct: 1386 AIMRDGVTHWSLSNSWDVDKGTFLSFSDRVSQSVVSAEVEMTAYALLTY-----TLLGDV 1440

Query: 1216 AKATSIVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVVKSTE-NFQR 1274
            A A  +V WL++QRNA GGFSSTQDT VALQALA+YA  +Y     + + + ST  ++Q 
Sbjct: 1441 AAALPVVKWLSQQRNALGGFSSTQDTCVALQALAEYAILSYAGGINLTVSLASTNLDYQE 1500

Query: 1275 TFNIQSVNRLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSL--SVE 1332
            TF +   N+ V Q   +P++P    + A G GC  +Q  + YN+  P     F L  S++
Sbjct: 1501 TFELHRTNQKVLQTAAIPSLPTGLFVSAKGDGCCLMQIDVTYNVPDPVAKPAFQLLVSLQ 1560

Query: 1333 IGKARCEQPTSPRS---------------------------LTLTIHTSYVGSRSSSNMA 1365
              +A+   P  P S                           + L + T ++ +  SSNMA
Sbjct: 1561 EPEAQGRPPPMPASAAEGSRGDWPPADDDDPAADQHHQEYKVMLEVCTRWLHA-GSSNMA 1619

Query: 1366 IVEVKMLSGF-SPMEGTNQLLLQQPL-VKKVEFGTDTLNIYLDELIKNTQT-YTFTISQS 1422
            ++EV +LSGF + +E   QLLL + + +K+ E     +  Y DE+     T   F   + 
Sbjct: 1620 VLEVPLLSGFRADIESLEQLLLDKHMGMKRYEVAGRRVLFYFDEIPSRCLTCVRFRALRE 1679

Query: 1423 VLVTNLKPATIKVYDYYLPDEQATIQYS 1450
             +V       + VYDYY P  +AT  Y+
Sbjct: 1680 CVVGRTSALPVSVYDYYEPAFEATRFYN 1707



 Score =  249 bits (635), Expect = 2e-65
 Identities = 246/991 (24%), Positives = 423/991 (42%), Gaps = 112/991 (11%)

Query: 1   MWAQLLLGMLALSP-----AIAEELPNYLVTLPA--RLNFPSVQKVCLDLSPGYSDVKFT 53
           +W  L L +L LS      A   + P YL+  P+  R     V  V +  SP    V+  
Sbjct: 53  LWPLLPLLLLLLSARDGVRAAQPQAPGYLIAAPSVFRAGVEEVISVTIFNSPREVTVQAQ 112

Query: 54  VTLETKDKTQK---LLEYSGLKKRHLHCISFLVPPPAGGTEEVATIRVSGVGNNIS---- 106
           +  + +   Q    +L+   +K +        VP    G    A ++V G G        
Sbjct: 113 LVAQGEPVVQSQGAILDKGTIKLK--------VPT---GLRGQALLKVWGRGWQAEEGPL 161

Query: 107 FEEKKKVLIQRQGNGTFVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSN 166
           F  +  V +  +G   F+QTDKP+Y P  +V   I T+  N  PVN+K     L DP  +
Sbjct: 162 FHNQTSVTVDGRGASVFIQTDKPVYRPQHRVLISIFTVSPNLRPVNEKLEAYIL-DPRGS 220

Query: 167 RIAQWLEVVPEQ-GIVDLSFQLAPEAMLGTYTVAVA-EGKTFG-TFSVEEYVLPKFKVEV 223
           R+ +W  + P   GI ++SF L+ + +LG + + V  +G  +  +F V++YVLPKF++ +
Sbjct: 221 RMIEWRHLKPFCCGITNMSFPLSDQPVLGEWFIFVEMQGHAYNKSFEVQKYVLPKFELLI 280

Query: 224 VEPKELSTVQESFLVKICCRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLS 283
             P+ +  +       +  RYT+GKP+ GA+ +++      Y+  EV R  L  +   + 
Sbjct: 281 DPPRYIQDLDACETGTVRARYTFGKPVAGALMINMTVNGVGYYSHEVGRPVL--RTTKIL 338

Query: 284 GQTDKTGCFSAPVDMATFDLIGYAYSHQINIVATVVEEGTGVEANATQNIYISPQMGSMT 343
           G  D   C     DM   D+  + +  +++I A V       +     +  +  Q+  + 
Sbjct: 339 GSRDFDICVR---DMIPADVPEH-FRGRVSIWAMVTSVDGSQQVAFDDSTPVQRQLVDIR 394

Query: 344 F-EDTSNFYHPNFPFSGKIRVRGHDDSFLKNHLVFLVIYGT-NGTFNQTLVTDNNGLAPF 401
           + +DT   + P   + GK+ +   D S  +   V +    T       + V    GL  F
Sbjct: 395 YSKDTRKQFKPGLAYVGKVELSYPDGSPAEGVTVQIKAELTPKDNIYTSEVVSQRGLVGF 454

Query: 402 TLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNGP 461
            + +   +   V LE K     +  N + V   Y  +YL L  +YS ++ +L +   + P
Sbjct: 455 EIPSIPTSAQHVWLETKV----MALNGKPVGAQYLPSYLSLGSWYSPSQCYLQLQPPSHP 510

Query: 462 LKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKAS---- 517
           L+ G+      + Y       P    +  Y +  +G++V+ GQ+  ++ ++  K +    
Sbjct: 511 LQVGE------EAYFSVKSTCP-CNFTLYYEVAARGNIVLSGQQPAHTTQQRSKRAAPAL 563

Query: 518 --------------------------FSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQ 551
                                      SL L  T  + P   L+++ +  +G  VAD +Q
Sbjct: 564 EKPIRLTHLSETEPPPAPEAEVDVCVTSLHLAVTPSMVPLGRLLVFYVRENGEGVADSLQ 623

Query: 552 FSVEMCFDNQVSLGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRS 611
           F+VE  F+NQVS+ +S ++  PG  V+L+++AA GS   + AVD+SV LLR    L+   
Sbjct: 624 FAVETFFENQVSVTYSANETQPGEVVDLRIRAARGSCVCVAAVDKSVYLLRSGFRLTPAQ 683

Query: 612 VYGMFPFWYGHYPYQVAEYDQCPVSGPWDFPQPLIDPMPQGHSSQRSIIWRPSFSEGTDL 671
           V+            ++ +YD     G      P           +RS ++   +    D 
Sbjct: 684 VF-----------QELEDYDVSDSFGVSREDGPFWWAGLTAQRRRRSSVFPWPWGITKDS 732

Query: 672 FSFFRDVGLKILSNAKIKKPVDCSHRSP---EYSTAMGAGGGHPEAFESSTPLHQ--AED 726
              F + GL ++++      V  +HR         A+ A   H  +  +  P       +
Sbjct: 733 GFAFTETGLVVMTDR-----VSLNHRQDGGLYTDEAVPAFQPHTGSLVAVAPSRHPPRTE 787

Query: 727 SQVRQYFPETWLWDLFPIGN-SGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGLT 785
            + R +FPETW+W    I + SG+  + V VPD+IT W   +   S S+G G++    L 
Sbjct: 788 KRKRTFFPETWIWHCLNISDPSGEGTLSVKVPDSITSWVGEAVALSTSQGLGIAEPSLLK 847

Query: 786 AFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADSQ---T 842
            FKPFFVD  LP  ++RGE  ++  +++NY+  C  V   L+     Q       +    
Sbjct: 848 TFKPFFVDFMLPALIIRGEQVKIPLSVYNYMGTCAEVYMKLSVPKGIQFVGHPGKRHVTK 907

Query: 843 SSCLCADEAKTHHWNITAVKLGHINFTISTKILDSNEPC-GGQKGFVPQKGRSDTLI--- 898
             C+   EA+     ++   LG  N T           C  G+    P++  +D  +   
Sbjct: 908 KMCVAPGEAEPIWVVLSFSDLGLNNITAKALAYGDTNCCRDGRSSKHPEENHADRRVPIG 967

Query: 899 -----KPVLVKPEGVLVEKTHSSLLCPKGKV 924
                + V+V+ EGV    T+S+  CP  +V
Sbjct: 968 VDHVRRSVMVEAEGVPRAYTYSAFFCPSERV 998


>gi|178557739 complement component 4B preproprotein [Homo sapiens]
          Length = 1744

 Score =  220 bits (560), Expect = 9e-57
 Identities = 207/829 (24%), Positives = 358/829 (43%), Gaps = 126/829 (15%)

Query: 725  EDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGL 784
            +D  VR +FPE WLW +  +     + + + +PD++T W+      S+++G  ++  V L
Sbjct: 770  DDIPVRSFFPENWLWRVETVDRF--QILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQL 827

Query: 785  TAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADSQTSS 844
              F+ F + L LP SV R E   L   ++NYL   + V   ++      L          
Sbjct: 828  RVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQV 887

Query: 845  CLCADEAKTHHWNITAVKLGHINFTISTKILDSNE-PCGGQKGFVPQKGRSDTLIKPVLV 903
             + A  A+   +++       ++  +  +   S E P G            D + K + +
Sbjct: 888  LVPAGSARPVAFSVVPTAATAVSLKVVAR--GSFEFPVG------------DAVSKVLQI 933

Query: 904  KPEGVLVEKTHSSLLCPKGKVASESVSLELP----VDIVPDST-KAYVTVLG----DIMG 954
            + EG +  +    L+     +     +LE+P     +++PD    +YV V      D +G
Sbjct: 934  EKEGAIHRE---ELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLG 990

Query: 955  T--ALQ--NLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKA---GLLTEEIRSRAVGFLE 1007
            +  AL    +  L+++P GCGEQ M+  AP +   +YL+K      L  E +  AV  ++
Sbjct: 991  SEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQ 1050

Query: 1008 IGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMA 1067
             GY +   ++ ++GSY+A+  R    +TWLTAFV K    AQ+ +   P+ +Q+   W+ 
Sbjct: 1051 KGYMRIQQFRKADGSYAAWLSR--GSSTWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLL 1108

Query: 1068 GNQLPSGCYANVGNLLHTAMKGGV---DDEVSLTAYVTAAL---LEMGKDVDDPMVSQGL 1121
              Q   G + ++  ++H +M+GG+   D+ V+LTA+VT AL   L + +D     + Q +
Sbjct: 1109 SQQQADGSFQDLSPVIHRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRV 1168

Query: 1122 RCLKNSATS---------TTNLYTQALLAYIFSLA-GEMDIRNILLKQLDQQAIISGESI 1171
                + A+S             +  A+ AY  +L     D+R +    L   A  +G+++
Sbjct: 1169 EASISKASSFLGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNL 1228

Query: 1172 YW-----------SQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATS 1220
            YW           S  P P + + P  +  A+ +E TAYALL  L    L + +   A  
Sbjct: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLL----LHEGKAEMADQ 1284

Query: 1221 IVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEE-INLVVKST-ENFQRTFNI 1278
              AWL +Q +  GGF STQDTV+AL AL+ Y   ++   E  +N+ + ST  N  ++  +
Sbjct: 1285 AAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHAL 1344

Query: 1279 QSVNRLV--FQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIG-K 1335
            Q  NR +   +++   ++     ++  G     ++ +  YN+L   N     L +E+  K
Sbjct: 1345 QLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVK 1404

Query: 1336 ARCE---------------------------QPTSPRSL--------------------- 1347
               E                           QP +P  L                     
Sbjct: 1405 GHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQES 1464

Query: 1348 --TLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLL--LQQPLVKKVEFGTDTLNI 1403
                T+     G    S MAI +V +LSGF  +    + L  L    V   E     + +
Sbjct: 1465 RVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLL 1524

Query: 1404 YLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDP 1452
            Y D +  + +   F   Q V V  ++PA+  +YDYY P+ + ++ Y  P
Sbjct: 1525 YFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 65/257 (25%), Positives = 116/257 (45%), Gaps = 22/257 (8%)

Query: 123 FVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVD 182
           F+QTD+P+Y PGQ+V +R+  +D    P  D  + V +++ +  R+ +  EV     I  
Sbjct: 142 FLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRK-KEVYMPSSIFQ 199

Query: 183 LSFQLAPEAMLGTYTVAV-----AEGKTFGTFSVEEYVLPKFKVEVVEPKE-LSTVQ--- 233
             F +   +  GT+ ++       E  +   F V++YVLP F+V++   K  + TV    
Sbjct: 200 DDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHL 259

Query: 234 ESFLVKICCRYTYGKPMLGAVQVS---VCQKANTYWYREVERE-QLPDKCRNLSGQTDKT 289
           +   + I  RY YGKP+ G   V    + +     ++R +E + +L +   ++S    + 
Sbjct: 260 DEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEF 319

Query: 290 GCFSAPVDMATFDLIGYAYSHQINIVATVVEE--GTGVEANATQNIYISPQMGSMTFEDT 347
                 ++M   DL G     ++ + A ++E   G   EA  T   ++S    S+    T
Sbjct: 320 QDALEKLNMGITDLQGL----RLYVAAAIIESPGGEMEEAELTSWYFVSSPF-SLDLSKT 374

Query: 348 SNFYHPNFPFSGKIRVR 364
                P  PF  +  VR
Sbjct: 375 KRHLVPGAPFLLQALVR 391


>gi|115298678 complement component 3 precursor [Homo sapiens]
          Length = 1663

 Score =  219 bits (559), Expect = 1e-56
 Identities = 211/784 (26%), Positives = 359/784 (45%), Gaps = 105/784 (13%)

Query: 724  AEDSQV-RQYFPETWLWDLFPIGNSGKEAV-----HVTVPDAITEWKAMSFCTSQSRGFG 777
            AE++ V R  FPE+WLW++  +    K  +     ++ + D+IT W+ ++   S  +G  
Sbjct: 757  AEENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGIC 816

Query: 778  LSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDC-IRVQTDLAKSHEYQLES 836
            ++    +T  + FF+DL LPYSVVR E   + A ++NY ++  ++V+ +L  +  +    
Sbjct: 817  VADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAF---- 872

Query: 837  WADSQTSSCLCADEAKTHHWNIT-----AVKLGHINFTISTKILDSNEPCGGQKGFVPQK 891
                    C  A   + H   +T     ++ + ++   + T + +          F+   
Sbjct: 873  --------CSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFI--- 921

Query: 892  GRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLE--LPVDI---VPDSTKAYV 946
              SD + K + V PEG+ + KT +       ++  E V  E   P D+   VPD T++  
Sbjct: 922  --SDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPD-TESET 978

Query: 947  TVLGDIMGTAL----------QNLDGLVQMPSGCGEQNMVLFAPIIYVLQYL------EK 990
             +L  + GT +          + L  L+  PSGCGEQNM+   P +  + YL      EK
Sbjct: 979  RIL--LQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEK 1036

Query: 991  AGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQK 1050
             GL   E R  A+  ++ GY ++L ++  + +++AF +R    +TWLTA+V K F  A  
Sbjct: 1037 FGL---EKRQGALELIKKGYTQQLAFRQPSSAFAAFVKR--APSTWLTAYVVKVFSLAVN 1091

Query: 1051 FIFIDPKNIQDALKWM-AGNQLPSGCYANVGNLLHTAMKGGV----DDEVSLTAYVTAAL 1105
             I ID + +  A+KW+    Q P G +     ++H  M GG+    + +++LTA+V  +L
Sbjct: 1092 LIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISL 1151

Query: 1106 LEMGKDVDDPMVSQGLRCLKNSATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAI 1165
             E  KD+ +  V+     +  +       Y     +Y  ++AG           L Q   
Sbjct: 1152 QE-AKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAG---------YALAQMGR 1201

Query: 1166 ISGESIYWSQKPTPSSNASPWSEPA--AVDVELTAYALLAQLTKPSLTQKEIAKATSIVA 1223
            + G  +  ++  T + + + W +P     +VE T+YALLA      L  K+      +V 
Sbjct: 1202 LKGPLL--NKFLTTAKDKNRWEDPGKQLYNVEATSYALLA-----LLQLKDFDFVPPVVR 1254

Query: 1224 WLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVV-----KSTENFQRTFNI 1278
            WL +QR   GG+ STQ T +  QALA+Y   A    +E+NL V       +       + 
Sbjct: 1255 WLNEQRYYGGGYGSTQATFMVFQALAQYQKDA-PDHQELNLDVSLQLPSRSSKITHRIHW 1313

Query: 1279 QSVNRLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARC 1338
            +S + L+  ++T  N     T E  GQG + V T+             F L V I K   
Sbjct: 1314 ESAS-LLRSEETKENEGFTVTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTI-KPAP 1371

Query: 1339 EQPTSPR----SLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSP--------MEGTNQLLL 1386
            E    P+    ++ L I T Y G + ++ M+I+++ M++GF+P          G ++ + 
Sbjct: 1372 ETEKRPQDAKNTMILEICTRYRGDQDAT-MSILDISMMTGFAPDTDDLKQLANGVDRYIS 1430

Query: 1387 QQPLVKKVEFGTDTLNIYLDELI-KNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQA 1445
            +  L K      +TL IYLD++         F + Q   V  ++P  +KVY YY  +E  
Sbjct: 1431 KYELDKAFS-DRNTLIIYLDKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESC 1489

Query: 1446 TIQY 1449
            T  Y
Sbjct: 1490 TRFY 1493



 Score =  105 bits (262), Expect = 3e-22
 Identities = 160/654 (24%), Positives = 272/654 (41%), Gaps = 90/654 (13%)

Query: 5   LLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQK 64
           LLL +L   P +A   P Y +  P  L   S + + L+      DV  TVT+   D   K
Sbjct: 9   LLLLLLTHLP-LALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH--DFPGK 65

Query: 65  LLEYSGLKK------RHLHCISFLVPP-----PAGGTEEVATIRVSGVGNNISFEEKKKV 113
            L  S  K        H+  ++F +P         G  +  T++ +  G  +    +K V
Sbjct: 66  KLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQAT-FGTQVV---EKVV 121

Query: 114 LIQRQGNGTFVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQ-WL 172
           L+  Q    F+QTDK +YTPG  V +RI T++   +PV  +  MV +++P    + Q  L
Sbjct: 122 LVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVG-RTVMVNIENPEGIPVKQDSL 180

Query: 173 EVVPEQGIVDLSFQLAPEAMLGTYTVAV----AEGKTFGT-FSVEEYVLPKFKVEVVEPK 227
               + G++ LS+ +     +G + +      +  + F T F V+EYVLP F+V +VEP 
Sbjct: 181 SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEV-IVEPT 239

Query: 228 ELSTV---QESFLVKICCRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNL-- 282
           E       ++   V I  R+ YGK + G   V    +         +R  LP+  + +  
Sbjct: 240 EKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGE------QRISLPESLKRIPI 293

Query: 283 ---SGQT--DKTGCFSAPVDMATFDLIGYAYSHQINIVATVV-EEGTGVEANATQNIYIS 336
              SG+    +        +    DL+G      + + ATV+   G+ +       I I 
Sbjct: 294 EDGSGEVVLSRKVLLDGVQNPRAEDLVG----KSLYVSATVILHSGSDMVQAERSGIPIV 349

Query: 337 PQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNN 396
                + F  T  ++ P  PF   + V   D S       + V     G      +T  +
Sbjct: 350 TSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGS-----PAYRVPVAVQGEDTVQSLTQGD 404

Query: 397 GLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQ----------NAYLHLRPFY 446
           G+A  ++ T   +   +S+  + + ++L    EQ  R  Q          N YLHL    
Sbjct: 405 GVAKLSINTHP-SQKPLSITVRTKKQEL-SEAEQATRTMQALPYSTVGNSNNYLHLSVLR 462

Query: 447 STTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEGQKH 506
           +  R    ++ +N  L+  +  E  + YY              +Y ++ KG L+  G++ 
Sbjct: 463 TELRPGETLN-VNFLLRMDRAHEAKIRYY--------------TYLIMNKGRLLKAGRQ- 506

Query: 507 LNSKKKGLKASFSLSLTFTSRLAPDPSLVIY--AIFPSG--GVVADKIQFSV-EMCFDN- 560
               ++  +    L L+ T+   P   LV Y   I  SG   VVAD +   V + C  + 
Sbjct: 507 ---VREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSL 563

Query: 561 QVSLGFSPSQQ-LPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRSVY 613
            V  G S  +Q +PG ++ L+++   G+   L AVD+ V +L    +L+   ++
Sbjct: 564 VVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIW 617


>gi|239740684 PREDICTED: similar to C4A protein isoform 1 [Homo
            sapiens]
          Length = 1744

 Score =  216 bits (549), Expect = 2e-55
 Identities = 207/829 (24%), Positives = 356/829 (42%), Gaps = 126/829 (15%)

Query: 725  EDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGL 784
            +D  VR +FPE WLW +  +     + + + +PD++T W+      S+++G  ++  V L
Sbjct: 770  DDIPVRSFFPENWLWRVETVDRF--QILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQL 827

Query: 785  TAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADSQTSS 844
              F+ F + L LP SV R E   L   ++NYL   + V   ++      L          
Sbjct: 828  RVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQV 887

Query: 845  CLCADEAKTHHWNITAVKLGHINFTISTKILDSNE-PCGGQKGFVPQKGRSDTLIKPVLV 903
             + A  A+   +++       ++  +  +   S E P G            D + K + +
Sbjct: 888  LVPAGSARPVAFSVVPTAAAAVSLKVVAR--GSFEFPVG------------DAVSKVLQI 933

Query: 904  KPEGVLVEKTHSSLLCPKGKVASESVSLELP----VDIVPDST-KAYVTVLG----DIMG 954
            + EG +  +    L+     +     +LE+P     +++PD    +YV V      D +G
Sbjct: 934  EKEGAIHRE---ELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLG 990

Query: 955  T--ALQ--NLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKA---GLLTEEIRSRAVGFLE 1007
            +  AL    +  L+++P GCGEQ M+  AP +   +YL+K      L  E +  AV  ++
Sbjct: 991  SEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQ 1050

Query: 1008 IGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMA 1067
             GY +   ++ ++GSY+A+  RD +  TWLTAFV K    AQ+ +   P+ +Q+   W+ 
Sbjct: 1051 KGYMRIQQFRKADGSYAAWLSRDSS--TWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLL 1108

Query: 1068 GNQLPSGCYANVGNLLHTAMKGGV---DDEVSLTAYVTAAL---LEMGKDVDDPMVSQGL 1121
              Q   G + +   +L  +M+GG+   D+ V+LTA+VT AL   L + +D     + Q +
Sbjct: 1109 SQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRV 1168

Query: 1122 RCLKNSATS---------TTNLYTQALLAYIFSLA-GEMDIRNILLKQLDQQAIISGESI 1171
                + A S             +  A+ AY  +L    +D+  +    L   A  +G+++
Sbjct: 1169 EASISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNL 1228

Query: 1172 YW-----------SQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATS 1220
            YW           S  P P + + P  +  A+ +E TAYALL  L    L + +   A  
Sbjct: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLL----LHEGKAEMADQ 1284

Query: 1221 IVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEE-INLVVKST-ENFQRTFNI 1278
              AWL +Q +  GGF STQDTV+AL AL+ Y   ++   E  +N+ + ST  N  ++  +
Sbjct: 1285 AAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHAL 1344

Query: 1279 QSVNRLV--FQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIG-K 1335
            Q  NR +   +++   ++     ++  G     ++ +  YN+L   N     L +E+  K
Sbjct: 1345 QLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVK 1404

Query: 1336 ARCE---------------------------QPTSPRSL--------------------- 1347
               E                           QP +P  L                     
Sbjct: 1405 GHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQES 1464

Query: 1348 --TLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLL--LQQPLVKKVEFGTDTLNI 1403
                T+     G    S MAI +V +LSGF  +    + L  L    V   E     + +
Sbjct: 1465 RVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLL 1524

Query: 1404 YLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDP 1452
            Y D +  + +   F   Q V V  ++PA+  +YDYY P+ + ++ Y  P
Sbjct: 1525 YFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 65/257 (25%), Positives = 116/257 (45%), Gaps = 22/257 (8%)

Query: 123 FVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVD 182
           F+QTD+P+Y PGQ+V +R+  +D    P  D  + V +++ +  R+ +  EV     I  
Sbjct: 142 FLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRK-KEVYMPSSIFQ 199

Query: 183 LSFQLAPEAMLGTYTVAV-----AEGKTFGTFSVEEYVLPKFKVEVVEPKE-LSTVQ--- 233
             F +   +  GT+ ++       E  +   F V++YVLP F+V++   K  + TV    
Sbjct: 200 DDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHL 259

Query: 234 ESFLVKICCRYTYGKPMLGAVQVS---VCQKANTYWYREVERE-QLPDKCRNLSGQTDKT 289
           +   + I  RY YGKP+ G   V    + +     ++R +E + +L +   ++S    + 
Sbjct: 260 DEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEF 319

Query: 290 GCFSAPVDMATFDLIGYAYSHQINIVATVVE--EGTGVEANATQNIYISPQMGSMTFEDT 347
                 ++M   DL G     ++ + A ++E   G   EA  T   ++S    S+    T
Sbjct: 320 QDALEKLNMGITDLQGL----RLYVAAAIIEYPGGEMEEAELTSWYFVSSPF-SLDLSKT 374

Query: 348 SNFYHPNFPFSGKIRVR 364
                P  PF  +  VR
Sbjct: 375 KRHLVPGAPFLLQALVR 391


>gi|67190748 complement component 4A preproprotein [Homo sapiens]
          Length = 1744

 Score =  215 bits (547), Expect = 3e-55
 Identities = 207/829 (24%), Positives = 356/829 (42%), Gaps = 126/829 (15%)

Query: 725  EDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGL 784
            +D  VR +FPE WLW +  +     + + + +PD++T W+      S+++G  ++  V L
Sbjct: 770  DDIPVRSFFPENWLWRVETVDRF--QILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQL 827

Query: 785  TAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADSQTSS 844
              F+ F + L LP SV R E   L   ++NYL   + V   ++      L          
Sbjct: 828  RVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQV 887

Query: 845  CLCADEAKTHHWNITAVKLGHINFTISTKILDSNE-PCGGQKGFVPQKGRSDTLIKPVLV 903
             + A  A+   +++       ++  +  +   S E P G            D + K + +
Sbjct: 888  LVPAGSARPVAFSVVPTAAAAVSLKVVAR--GSFEFPVG------------DAVSKVLQI 933

Query: 904  KPEGVLVEKTHSSLLCPKGKVASESVSLELP----VDIVPDST-KAYVTVLG----DIMG 954
            + EG +  +    L+     +     +LE+P     +++PD    +YV V      D +G
Sbjct: 934  EKEGAIHRE---ELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLG 990

Query: 955  T--ALQ--NLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKA---GLLTEEIRSRAVGFLE 1007
            +  AL    +  L+++P GCGEQ M+  AP +   +YL+K      L  E +  AV  ++
Sbjct: 991  SEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQ 1050

Query: 1008 IGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMA 1067
             GY +   ++ ++GSY+A+  RD +  TWLTAFV K    AQ+ +   P+ +Q+   W+ 
Sbjct: 1051 KGYMRIQQFRKADGSYAAWLSRDSS--TWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLL 1108

Query: 1068 GNQLPSGCYANVGNLLHTAMKGGV---DDEVSLTAYVTAAL---LEMGKDVDDPMVSQGL 1121
              Q   G + +   +L  +M+GG+   D+ V+LTA+VT AL   L + +D     + Q +
Sbjct: 1109 SQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRV 1168

Query: 1122 RCLKNSATS---------TTNLYTQALLAYIFSLA-GEMDIRNILLKQLDQQAIISGESI 1171
                + A S             +  A+ AY  +L    +D+  +    L   A  +G+++
Sbjct: 1169 EASISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNL 1228

Query: 1172 YW-----------SQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATS 1220
            YW           S  P P + + P  +  A+ +E TAYALL  L    L + +   A  
Sbjct: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLL----LHEGKAEMADQ 1284

Query: 1221 IVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEE-INLVVKST-ENFQRTFNI 1278
              AWL +Q +  GGF STQDTV+AL AL+ Y   ++   E  +N+ + ST  N  ++  +
Sbjct: 1285 ASAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHAL 1344

Query: 1279 QSVNRLV--FQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIG-K 1335
            Q  NR +   +++   ++     ++  G     ++ +  YN+L   N     L +E+  K
Sbjct: 1345 QLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVK 1404

Query: 1336 ARCE---------------------------QPTSPRSL--------------------- 1347
               E                           QP +P  L                     
Sbjct: 1405 GHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQES 1464

Query: 1348 --TLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGTNQLL--LQQPLVKKVEFGTDTLNI 1403
                T+     G    S MAI +V +LSGF  +    + L  L    V   E     + +
Sbjct: 1465 RVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLL 1524

Query: 1404 YLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYSDP 1452
            Y D +  + +   F   Q V V  ++PA+  +YDYY P+ + ++ Y  P
Sbjct: 1525 YFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAP 1573



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 65/257 (25%), Positives = 116/257 (45%), Gaps = 22/257 (8%)

Query: 123 FVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVD 182
           F+QTD+P+Y PGQ+V +R+  +D    P  D  + V +++ +  R+ +  EV     I  
Sbjct: 142 FLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRK-KEVYMPSSIFQ 199

Query: 183 LSFQLAPEAMLGTYTVAV-----AEGKTFGTFSVEEYVLPKFKVEVVEPKE-LSTVQ--- 233
             F +   +  GT+ ++       E  +   F V++YVLP F+V++   K  + TV    
Sbjct: 200 DDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHL 259

Query: 234 ESFLVKICCRYTYGKPMLGAVQVS---VCQKANTYWYREVERE-QLPDKCRNLSGQTDKT 289
           +   + I  RY YGKP+ G   V    + +     ++R +E + +L +   ++S    + 
Sbjct: 260 DEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEF 319

Query: 290 GCFSAPVDMATFDLIGYAYSHQINIVATVVEE--GTGVEANATQNIYISPQMGSMTFEDT 347
                 ++M   DL G     ++ + A ++E   G   EA  T   ++S    S+    T
Sbjct: 320 QDALEKLNMGITDLQGL----RLYVAAAIIESPGGEMEEAELTSWYFVSSPF-SLDLSKT 374

Query: 348 SNFYHPNFPFSGKIRVR 364
                P  PF  +  VR
Sbjct: 375 KRHLVPGAPFLLQALVR 391


>gi|239740686 PREDICTED: similar to C4A protein isoform 2 [Homo
            sapiens]
          Length = 1698

 Score =  212 bits (540), Expect = 2e-54
 Identities = 195/783 (24%), Positives = 343/783 (43%), Gaps = 80/783 (10%)

Query: 725  EDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGL 784
            +D  VR +FPE WLW +  +     + + + +PD++T W+      S+++G  ++  V L
Sbjct: 770  DDIPVRSFFPENWLWRVETVDRF--QILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQL 827

Query: 785  TAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQLESWADSQTSS 844
              F+ F + L LP SV R E   L   ++NYL   + V   ++      L          
Sbjct: 828  RVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQV 887

Query: 845  CLCADEAKTHHWNITAVKLGHINFTISTKILDSNE-PCGGQKGFVPQKGRSDTLIKPVLV 903
             + A  A+   +++       ++  +  +   S E P G            D + K + +
Sbjct: 888  LVPAGSARPVAFSVVPTAAAAVSLKVVAR--GSFEFPVG------------DAVSKVLQI 933

Query: 904  KPEGVLVEKTHSSLLCPKGKVASESVSLELP----VDIVPDST-KAYVTVLG----DIMG 954
            + EG +  +    L+     +     +LE+P     +++PD    +YV V      D +G
Sbjct: 934  EKEGAIHRE---ELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLG 990

Query: 955  T--ALQ--NLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKA---GLLTEEIRSRAVGFLE 1007
            +  AL    +  L+++P GCGEQ M+  AP +   +YL+K      L  E +  AV  ++
Sbjct: 991  SEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQ 1050

Query: 1008 IGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFIDPKNIQDALKWMA 1067
             GY +   ++ ++GSY+A+  RD +  TWLTAFV K    AQ+ +   P+ +Q+   W+ 
Sbjct: 1051 KGYMRIQQFRKADGSYAAWLSRDSS--TWLTAFVLKVLSLAQEQVGGSPEKLQETSNWLL 1108

Query: 1068 GNQLPSGCYANVGNLLHTAMKGGV---DDEVSLTAYVTAAL---LEMGKDVDDPMVSQGL 1121
              Q   G + +   +L  +M+GG+   D+ V+LTA+VT AL   L + +D     + Q +
Sbjct: 1109 SQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRV 1168

Query: 1122 RCLKNSATS---------TTNLYTQALLAYIFSLA-GEMDIRNILLKQLDQQAIISGESI 1171
                + A S             +  A+ AY  +L    +D+  +    L   A  +G+++
Sbjct: 1169 EASISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNL 1228

Query: 1172 YW-----------SQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATS 1220
            YW           S  P P + + P  +  A+ +E TAYALL  L    L + +   A  
Sbjct: 1229 YWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLL----LHEGKAEMADQ 1284

Query: 1221 IVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEE-INLVVKST-ENFQRTFNI 1278
              AWL +Q +  GGF STQDTV+AL AL+ Y   ++   E  +N+ + ST  N  ++  +
Sbjct: 1285 AAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHAL 1344

Query: 1279 QSVNRLV--FQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIG-K 1335
            Q  NR +   +++   ++     ++  G     ++ +  YN+L   N     L +E+  K
Sbjct: 1345 QLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVK 1404

Query: 1336 ARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFS------PMEGTNQLLLQQP 1389
               E                + ++   +  +  V  L  F         E      L   
Sbjct: 1405 GHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKLTSLSDR 1464

Query: 1390 LVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQY 1449
             V   E     + +Y D +  + +   F   Q V V  ++PA+  +YDYY P+ + ++ Y
Sbjct: 1465 YVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFY 1524

Query: 1450 SDP 1452
              P
Sbjct: 1525 GAP 1527



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 65/257 (25%), Positives = 116/257 (45%), Gaps = 22/257 (8%)

Query: 123 FVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVD 182
           F+QTD+P+Y PGQ+V +R+  +D    P  D  + V +++ +  R+ +  EV     I  
Sbjct: 142 FLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRK-KEVYMPSSIFQ 199

Query: 183 LSFQLAPEAMLGTYTVAV-----AEGKTFGTFSVEEYVLPKFKVEVVEPKE-LSTVQ--- 233
             F +   +  GT+ ++       E  +   F V++YVLP F+V++   K  + TV    
Sbjct: 200 DDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHL 259

Query: 234 ESFLVKICCRYTYGKPMLGAVQVS---VCQKANTYWYREVERE-QLPDKCRNLSGQTDKT 289
           +   + I  RY YGKP+ G   V    + +     ++R +E + +L +   ++S    + 
Sbjct: 260 DEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKTFFRGLESQTKLVNGQSHISLSKAEF 319

Query: 290 GCFSAPVDMATFDLIGYAYSHQINIVATVVE--EGTGVEANATQNIYISPQMGSMTFEDT 347
                 ++M   DL G     ++ + A ++E   G   EA  T   ++S    S+    T
Sbjct: 320 QDALEKLNMGITDLQGL----RLYVAAAIIEYPGGEMEEAELTSWYFVSSPF-SLDLSKT 374

Query: 348 SNFYHPNFPFSGKIRVR 364
                P  PF  +  VR
Sbjct: 375 KRHLVPGAPFLLQALVR 391


>gi|169218213 PREDICTED: similar to complement component C3, partial
            [Homo sapiens]
          Length = 1295

 Score =  181 bits (460), Expect = 3e-45
 Identities = 160/581 (27%), Positives = 274/581 (47%), Gaps = 83/581 (14%)

Query: 724  AEDSQV-RQYFPETWLWDLFPIGNSGKEAV-----HVTVPDAITEWKAMSFCTSQSRGFG 777
            AE++ V R  FPE+WLW++  +    K  +     ++ + D+IT W+ ++   S  +G  
Sbjct: 757  AEENIVSRSEFPESWLWNVEDLKEPPKNGISTKLMNIFLKDSITTWEILAVSMSDKKGIC 816

Query: 778  LSPTVGLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDC-IRVQTDLAKSHEYQLES 836
            ++    +T  + FF+DL LPYSVVR E   + A ++NY ++  ++V+ +L  +  +    
Sbjct: 817  VADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYRQNQELKVRVELLHNPAF---- 872

Query: 837  WADSQTSSCLCADEAKTHHWNIT-----AVKLGHINFTISTKILDSNEPCGGQKGFVPQK 891
                    C  A   + H   +T     ++ + ++   + T + +          F+   
Sbjct: 873  --------CSLATTKRRHQQTVTIPPKSSLSVPYVIVPLKTGLQEVEVKAAVYHHFI--- 921

Query: 892  GRSDTLIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLE--LPVDI---VPDSTKAYV 946
              SD + K + V PEG+ + KT +       ++  E V  E   P D+   VPD T++  
Sbjct: 922  --SDGVRKSLKVVPEGIRMNKTVAVRTLDPERLGREGVQKEDIPPADLSDQVPD-TESET 978

Query: 947  TVLGDIMGTAL----------QNLDGLVQMPSGCGEQNMVLFAPIIYVLQYL------EK 990
             +L  + GT +          + L  L+  PSGCGEQNM+   P +  + YL      EK
Sbjct: 979  RIL--LQGTPVAQMTEDAVDAERLKHLIVTPSGCGEQNMIGMTPTVIAVHYLDETEQWEK 1036

Query: 991  AGLLTEEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQK 1050
             GL   E R  A+  ++ GY ++L ++  + +++AF +R    +TWLTA+V K F  A  
Sbjct: 1037 FGL---EKRQGALELIKKGYTQQLAFRQPSSAFAAFVKR--APSTWLTAYVVKVFSLAVN 1091

Query: 1051 FIFIDPKNIQDALKWM-AGNQLPSGCYANVGNLLHTAMKGGV----DDEVSLTAYVTAAL 1105
             I ID + +  A+KW+    Q P G +     ++H  M GG+    + +++LTA+V  +L
Sbjct: 1092 LIAIDSQVLCGAVKWLILEKQKPDGVFQEDAPVIHQEMIGGLRNNNEKDMALTAFVLISL 1151

Query: 1106 LEMGKDVDDPMVSQGLRCLKNSATSTTNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAI 1165
             E  KD+ +  V+     +  +       Y     +Y  ++AG           L Q   
Sbjct: 1152 QE-AKDICEEQVNSLPGSITKAGDFLEANYMNLQRSYTVAIAG---------YALAQMGR 1201

Query: 1166 ISGESIYWSQKPTPSSNASPWSEPA--AVDVELTAYALLAQLTKPSLTQKEIAKATSIVA 1223
            + G  +  ++  T + + + W +P     +VE T+YALLA      L  K+      +V 
Sbjct: 1202 LKGPLL--NKFLTTAKDKNRWEDPGKQLYNVEATSYALLA-----LLQLKDFDFVPPVVR 1254

Query: 1224 WLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINL 1264
            WL +QR   GG+ STQ T +  QALA+Y   A    +E+NL
Sbjct: 1255 WLNEQRYYGGGYGSTQATFMVFQALAQYQKDA-PDHQELNL 1294



 Score =  107 bits (266), Expect = 1e-22
 Identities = 160/654 (24%), Positives = 273/654 (41%), Gaps = 90/654 (13%)

Query: 5   LLLGMLALSPAIAEELPNYLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQK 64
           LLL +L   P +A   P Y +  P  L   S + + L+      DV  TVT+   D   K
Sbjct: 9   LLLLLLTHLP-LALGSPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVH--DFPGK 65

Query: 65  LLEYSGLKK------RHLHCISFLVPP-----PAGGTEEVATIRVSGVGNNISFEEKKKV 113
            L  S  K        H+  ++F +P         G  +  T++ +  G  +    +K V
Sbjct: 66  KLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGRNKFVTVQAT-FGTQVV---EKVV 121

Query: 114 LIQRQGNGTFVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQ-WL 172
           L+  Q    F+QTDK +YTPG  V +RI T++   +PV  +  MV +++P    + Q  L
Sbjct: 122 LVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVNHKLLPVG-RTVMVNIENPEGIPVKQDSL 180

Query: 173 EVVPEQGIVDLSFQLAPEAMLGTYTVAV----AEGKTFGT-FSVEEYVLPKFKVEVVEPK 227
               + G++ LS+ +     +G + +      +  + F T F V+EYVLP F+V +VEP 
Sbjct: 181 SSQNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEFEVKEYVLPSFEV-IVEPT 239

Query: 228 ELSTV---QESFLVKICCRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNL-- 282
           E       ++   V I  R+ YGK + G   V    +         +R  LP+  + +  
Sbjct: 240 EKFYYIYNEKGLEVTITARFLYGKKVEGTAFVIFGIQDGE------QRISLPESLKRIPI 293

Query: 283 ---SGQT--DKTGCFSAPVDMATFDLIGYAYSHQINIVATVV-EEGTGVEANATQNIYIS 336
              SG+    +        ++   DL+G      + + ATV+   G+ +       I I 
Sbjct: 294 EDGSGEVVLSRKVLLDGVQNLRAEDLVG----KSLYVSATVILHSGSDMVQAERSGIPIV 349

Query: 337 PQMGSMTFEDTSNFYHPNFPFSGKIRVRGHDDSFLKNHLVFLVIYGTNGTFNQTLVTDNN 396
                + F  T  ++ P  PF   + V   D S       + V     G      +T  +
Sbjct: 350 TSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGS-----PAYRVPVAVQGEDTVQSLTQGD 404

Query: 397 GLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQ----------NAYLHLRPFY 446
           G+A  ++ T   +   +S+  + + ++L    EQ  R  Q          N YLHL    
Sbjct: 405 GVAKLSINTHP-SQKPLSITVRTKKQEL-SEAEQATRTMQALPYSTVGNSNNYLHLSVLR 462

Query: 447 STTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEGQKH 506
           +  R    ++ +N  L+  +  E  + YY              +Y ++ KG L+  G++ 
Sbjct: 463 TELRPGETLN-VNFLLRMDRAHEAKIRYY--------------TYLIMNKGRLLKAGRQ- 506

Query: 507 LNSKKKGLKASFSLSLTFTSRLAPDPSLVIY--AIFPSG--GVVADKIQFSV-EMCFDN- 560
               ++  +    L L+ T+   P   LV Y   I  SG   VVAD +   V + C  + 
Sbjct: 507 ---VREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASGQREVVADSVWVDVKDSCVGSL 563

Query: 561 QVSLGFSPSQQ-LPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRSVY 613
            V  G S  +Q +PG ++ L+++   G+   L AVD+ V +L    +L+   ++
Sbjct: 564 VVKSGQSEDRQPVPGQQMTLKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIW 617


>gi|38016947 complement component 5 preproprotein [Homo sapiens]
          Length = 1676

 Score =  181 bits (458), Expect = 6e-45
 Identities = 185/782 (23%), Positives = 355/782 (45%), Gaps = 94/782 (12%)

Query: 728  QVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTVGLTAF 787
            ++R YFPE+WLW++  +    ++ +   +PD++T W+      S + G  ++ TV    F
Sbjct: 764  EIRSYFPESWLWEVHLVPR--RKQLQFALPDSLTTWEIQGVGISNT-GICVADTVKAKVF 820

Query: 788  KPFFVDLTLPYSVVRGESFRLTATIFNY----LKDCIRVQ-TDLAKSHEYQLESWADSQT 842
            K  F+++ +PYSVVRGE  +L  T++NY    ++ C+++   +   + E  +     +++
Sbjct: 821  KDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKS 880

Query: 843  SSCL--CADEAKTHHWNITA----VKLGHINFTISTKILDSNEPCGGQKGFVPQKGRSDT 896
            S C+    + + +H    T     + L +INF++ T                      + 
Sbjct: 881  SKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWF------------------GKEI 922

Query: 897  LIKPVLVKPEGVLVEKTHSSLLCPKGKVASESVSLE----LPVDIVPDS-TKAYVTVLGD 951
            L+K + V PEGV  E      L P+G   + S   E    +P+D+VP +  K  ++V G 
Sbjct: 923  LVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGL 982

Query: 952  IMGTAL------QNLDGLVQMPSGCGEQNMVLFAPIIYVLQYLEKAG----------LLT 995
            ++G  L      + ++ L  +P G  E  ++   P+ YV  YLE             +  
Sbjct: 983  LVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEK 1042

Query: 996  EEIRSRAVGFLEIGYQKELMYKHSNGSYSAFGERDGNGNTWLTAFVTKCFGQAQKFIFID 1055
            ++++ +    L+ G    + Y++++ SYS +  + G+ +TWLTAF  +  GQ  K++  +
Sbjct: 1043 QKLKKK----LKEGMLSIMSYRNADYSYSVW--KGGSASTWLTAFALRVLGQVNKYVEQN 1096

Query: 1056 PKNIQDALKWMAGN-QLPSGCYANVGNLLHTAMKGGV-----DDEVSLTAYVTAALLEMG 1109
              +I ++L W+  N QL +G +          ++G +     ++ + LTA+    + +  
Sbjct: 1097 QNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAF 1156

Query: 1110 K-----DVDDPMVSQGLRCLKNSATSTTNLYTQALLAYIFSLAGEMDIR-NILLKQLDQQ 1163
                   +D  ++      L+N+  + +  +T A+ AY  SL  +   +   ++  L ++
Sbjct: 1157 DICPLVKIDTALIKADNFLLENTLPAQST-FTLAISAYALSLGDKTHPQFRSIVSALKRE 1215

Query: 1164 AIISGES---IYWSQKPTPSSNASPWSEPAAVDVELTAYALLAQLTKPSLTQKEIAKATS 1220
            A++ G      +W        ++ P +  A + VE TAYALL      SL  K+I     
Sbjct: 1216 ALVKGNPPIYRFWKDNLQHKDSSVPNTGTARM-VETTAYALLT-----SLNLKDINYVNP 1269

Query: 1221 IVAWLAKQRNAYGGFSSTQDTVVALQALAKYATTAYMPSEEINLVVK-STENFQRTFNIQ 1279
            ++ WL++++   GGF STQDT+ A++ L +Y+         +++ V    +     + + 
Sbjct: 1270 VIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKGALHNYKMT 1329

Query: 1280 SVNRLVFQQDTLPNVPGMY-TLEASGQGCVYVQTVLRYNILPPTNMKTFSLSV---EIGK 1335
              N L    + L N   +  T   SG   V+V TV+ +       + +F L +   +I  
Sbjct: 1330 DKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVV-HKTSTSEEVCSFYLKIDTQDIEA 1388

Query: 1336 ARCEQPTSPRSLTLTIHTSYVGSR----SSSNMAIVEVKMLSGFSPMEGTNQLLLQ--QP 1389
            +      +     +    SY  SR    S S+ A++++ + +G S  E   + L++    
Sbjct: 1389 SHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQ 1448

Query: 1390 LVKKVEFGTDTLNIYLDEL-IKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQ 1448
            L    +     + + L+ +   +     F I +   V  L PAT  VY+Y+ PD+Q T+ 
Sbjct: 1449 LFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMF 1508

Query: 1449 YS 1450
            YS
Sbjct: 1509 YS 1510



 Score = 97.1 bits (240), Expect = 1e-19
 Identities = 145/626 (23%), Positives = 250/626 (39%), Gaps = 89/626 (14%)

Query: 23  YLVTLPARLNFPSVQKVCLDLSPGYSDVKFTVTLETKDKTQKLLEYSGLKKRHLHCIS-- 80
           Y+++ P      + + + + +  GY++  F  T+  K    K   YS     H+H  S  
Sbjct: 23  YVISAPKIFRVGASENIVIQVY-GYTEA-FDATISIKSYPDKKFSYSS---GHVHLSSEN 77

Query: 81  -------FLVPPPA--GGTEEVATIRVSGVGNNISFEEKKKVLIQRQGNGTFVQTDKPLY 131
                    + P    GG   V+ + +  V  +  F + K++ I       F+ TDKP+Y
Sbjct: 78  KFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKH--FSKSKRMPITYDNGFLFIHTDKPVY 135

Query: 132 TPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVDL-SFQLAPE 190
           TP Q V  R+ +++ +  P   + +++   DP  + +   +E +   GI+    F++   
Sbjct: 136 TPDQSVKVRVYSLNDDLKPAK-RETVLTFIDPEGSEV-DMVEEIDHIGIISFPDFKIPSN 193

Query: 191 AMLGTYTVAVAEGKTFGT-----FSVEEYVLPKFKVEVVEPKELSTVQ----ESFLVKIC 241
              G +T+     + F T     F V+EYVLP F V  +EP E + +     ++F + I 
Sbjct: 194 PRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVS-IEP-EYNFIGYKNFKNFEITIK 251

Query: 242 CRYTYGKPMLGAVQVSVCQKANTYWYREVEREQLPDKCRNLSGQTDKTGCFSAPVDMATF 301
            RY Y K         V  +A+ Y    + RE L D  + +     +       +   TF
Sbjct: 252 ARYFYNK---------VVTEADVYITFGI-REDLKDDQKEMMQTAMQNTMLINGIAQVTF 301

Query: 302 DL------IGYAYSHQIN-----IVATVVEEGTGVEANAT---QNIYISPQMGSMTFEDT 347
           D       + Y     +N     I  TV+E   G    A        +SP    +    T
Sbjct: 302 DSETAVKELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPY--KLNLVAT 359

Query: 348 SNFYHPNFPFSGKIRVRGHDDSFLKNHLVFL------VIYGTNGTFNQTLVTD-NNGLAP 400
             F  P  P+  K++V+   D  +    V L      V   T+       VT  ++G+A 
Sbjct: 360 PLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLDPSKSVTRVDDGVAS 419

Query: 401 FTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLRPFYSTTRSFLGIHRLNG 460
           F L       T +    K    DL    +    Y   AY       S ++S+L I   + 
Sbjct: 420 FVLNLPS-GVTVLEFNVKTDAPDLPEENQAREGYRAIAY------SSLSQSYLYIDWTDN 472

Query: 461 --PLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEGQKHLNSKKKGLKASF 518
              L  G+   ++V     P     D+   ++Y ++ KG ++     H  +++K   AS+
Sbjct: 473 HKALLVGEHLNIIV----TPKSPYIDKITHYNYLILSKGKII-----HFGTREKFSDASY 523

Query: 519 -SLSLTFTSRLAPDPSLVIYAIF---PSGGVVADKIQFSVEMCFDNQVSLGFSPSQQL-- 572
            S+++  T  + P   L++Y I     +  +V+D +  ++E    NQ+ +  SP      
Sbjct: 524 QSINIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLSPDADAYS 583

Query: 573 PGAEVELQLQAAPGSLCALRAVDESV 598
           PG  V L +     S  AL AVD +V
Sbjct: 584 PGQTVSLNMATGMDSWVALAAVDSAV 609


>gi|239752557 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 261

 Score =  129 bits (324), Expect = 2e-29
 Identities = 79/229 (34%), Positives = 120/229 (52%), Gaps = 1/229 (0%)

Query: 384 NGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLR 443
           N  F     TD NG A F+++TS     + +L+  +   +  Y P  +   Y +A+  + 
Sbjct: 11  NDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFLVS 70

Query: 444 PFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEG 503
            FYS T SFL I      L+C   + V V Y ++      D  + F +YL    S   + 
Sbjct: 71  RFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKF-FYLCTSDSGNFQH 129

Query: 504 QKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSVEMCFDNQVS 563
           +   +        +FS  L+ ++ LAP   L +Y + PSG +VAD ++F V+ CF ++V+
Sbjct: 130 RISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVN 189

Query: 564 LGFSPSQQLPGAEVELQLQAAPGSLCALRAVDESVLLLRPDRELSNRSV 612
           + FS  Q LPG+   L LQAAP   CALRAVD +VLLL+ +++LS  SV
Sbjct: 190 IKFSNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESV 238


>gi|239758130 PREDICTED: similar to complement component 4B (Childo
            blood group), partial [Homo sapiens]
          Length = 666

 Score =  125 bits (314), Expect = 3e-28
 Identities = 124/499 (24%), Positives = 207/499 (41%), Gaps = 88/499 (17%)

Query: 1038 TAFVTKCFGQAQKFIFIDPKNIQDALKWMAGNQLPSGCYANVGNLLHTAMKGGV---DDE 1094
            TAFV K    AQ+ +    + +Q+   W+   Q   G + ++  ++H +M+GG+   D+ 
Sbjct: 1    TAFVLKVLSLAQEQVGGSREKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDET 60

Query: 1095 VSLTAYVTAAL---LEMGKDVDDPMVSQGLRCLKNSATS---------TTNLYTQALLAY 1142
            V+LTA+VT AL   L + +D     + Q +    + A S             +  A+ AY
Sbjct: 61   VALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAY 120

Query: 1143 IFSLA-GEMDIRNILLKQLDQQAIISGESIYW-----------SQKPTPSSNASPWSEPA 1190
              +L     D+R +    L   A  +G+++YW           S  P P + + P  +  
Sbjct: 121  ALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAP 180

Query: 1191 AVDVELTAYALLAQLTKPSLTQKEIAKATSIVAWLAKQRNAYGGFSSTQDTVVALQALAK 1250
            A+ +E TAYALL  L    L + +   A    AWL +Q +  GGF STQDTV+AL AL+ 
Sbjct: 181  ALWIETTAYALLHLL----LHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSA 236

Query: 1251 YATTAYMPSEE-INLVVKST-ENFQRTFNIQSVNRLV--FQQDTLPNVPGMYTLEASGQG 1306
            Y   ++   E  +N+ + ST  N  ++  +Q  NR +   +++   ++     ++  G  
Sbjct: 237  YWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNS 296

Query: 1307 CVYVQTVLRYNILPPTNMKTFSLSVEIG-KARCE-------------------------- 1339
               ++ +  YN+L   N     L +E+  K   E                          
Sbjct: 297  KGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAP 356

Query: 1340 -QPTSPRSL-----------------------TLTIHTSYVGSRSSSNMAIVEVKMLSGF 1375
             QP +P  L                         T+     G    S MAI +V +LSGF
Sbjct: 357  LQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGF 416

Query: 1376 SPMEGTNQLL--LQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATI 1433
              +    + L  L    V   E     + +Y D +  + +   F   Q V V  ++PA+ 
Sbjct: 417  HALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASA 476

Query: 1434 KVYDYYLPDEQATIQYSDP 1452
             +YDYY P+ + ++ Y  P
Sbjct: 477  TLYDYYNPERRCSVFYGAP 495


>gi|239755748 PREDICTED: ovostatin [Homo sapiens]
          Length = 257

 Score =  122 bits (307), Expect = 2e-27
 Identities = 65/189 (34%), Positives = 101/189 (53%), Gaps = 5/189 (2%)

Query: 1262 INLVVKSTENFQRTFNIQSVNRLVFQQDTLPNVPGMYTLEASGQGCVYVQTVLRYNILPP 1321
            +++    +E     F +   NRL+ Q+  +   PG YT++  G GC ++Q  L+YN+L P
Sbjct: 66   LSVSASRSEGSSEIFQVNGHNRLLVQRSEVTQAPGQYTVDVEGHGCTFIQATLKYNVLLP 125

Query: 1322 TNMKTFSLSVEIGKARCEQPTSPRSLTLTIHTSYVGSRSSSNMAIVEVKMLSGFSPMEGT 1381
                 FSLS+EI K       S  +  LT+   Y G R+ S+M +++VKMLSGF+P   +
Sbjct: 126  KKASGFSLSLEIVKNY-----SSTAFDLTVTLKYTGIRNKSSMVVIDVKMLSGFTPTMSS 180

Query: 1382 NQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLP 1441
             + L  +  V K E   D +  YL+       ++ F++ QS LV N++PA   VYDYY  
Sbjct: 181  IEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSNLVFNIQPAPAMVYDYYEK 240

Query: 1442 DEQATIQYS 1450
            +E A   Y+
Sbjct: 241  EEYALAFYN 249


>gi|169217711 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 278

 Score =  110 bits (275), Expect = 1e-23
 Identities = 66/212 (31%), Positives = 99/212 (46%), Gaps = 18/212 (8%)

Query: 678 VGLKILSNAKIKKPVDCSHR------SPEYSTAMGAG---------GGHPEAFESSTPLH 722
           +GLK+ +N   +KP  C          P Y      G                E++  + 
Sbjct: 1   MGLKVFTNLHYRKPEVCVMERRLPLPKPLYLETENYGPMRSVPSRIASSGIRGENADYVE 60

Query: 723 QAEDSQVRQYFPETWLWDLFPIGNSGKEAVHVTVPDAITEWKAMSFCTSQSRGFGLSPTV 782
           QA    VR  FPETW+WDL  + +SG   +   +PD IT+W+A  FC +   GFG+S T 
Sbjct: 61  QAIIQTVRTNFPETWMWDLVSVDSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTT 120

Query: 783 GLTAFKPFFVDLTLPYSVVRGESFRLTATIFNYLKDCIRVQTDLAKSHEYQ--LESWADS 840
            L   +PFF+++  P+SVV+ E F L   +F+Y   C+ +   + +S  Y+  + +W   
Sbjct: 121 TLEVSQPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEISVQVEESQNYEANINTW-KI 179

Query: 841 QTSSCLCADEAKTHHWNITAVKLGHINFTIST 872
             S  + A   KT+ W I   KL      IST
Sbjct: 180 NGSEVIQAGGRKTNIWTIIPKKLDLKFLNIST 211


>gi|239752555 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 195

 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 52/179 (29%), Positives = 85/179 (47%), Gaps = 1/179 (0%)

Query: 384 NGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLR 443
           N  F     TD NG A F+++TS     + +L+  +   +  Y P  +   Y +A+  + 
Sbjct: 11  NDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFLVS 70

Query: 444 PFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSYYLIGKGSLVMEG 503
            FYS T SFL I      L+C   + V V Y ++      D  + F +YL    S   + 
Sbjct: 71  RFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKF-FYLCTSDSGNFQH 129

Query: 504 QKHLNSKKKGLKASFSLSLTFTSRLAPDPSLVIYAIFPSGGVVADKIQFSVEMCFDNQV 562
           +   +        +FS  L+ ++ LAP   L +Y + PSG +VAD ++F V+ CF ++V
Sbjct: 130 RISSSPIYTAWNGNFSFPLSISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKV 188


>gi|169217713 PREDICTED: similar to Ovostatin homolog 2 [Homo sapiens]
          Length = 189

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 54/140 (38%), Positives = 73/140 (52%), Gaps = 10/140 (7%)

Query: 1115 PMVSQGLRCLKNSATS-TTNLYTQALLAYIFSLAGEMDIRNILLKQLDQQAIISGESIYW 1173
            P +   L CL+ +  S  TN Y  A+LAY F+LAG+      LL+ LDQ A      IYW
Sbjct: 48   PALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSATKLNNVIYW 107

Query: 1174 SQKPTPSSNASPWSEPAA--VDVELTAYALLAQLTK--PSLTQKEIAKATSIVAWLAKQR 1229
             ++  P +   P   P A     E + Y LLA +++  P LT      A+ IV WLA+Q 
Sbjct: 108  ERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTY-----ASKIVQWLAQQM 162

Query: 1230 NAYGGFSSTQDTVVALQALA 1249
            N++GGFSS Q   V L  +A
Sbjct: 163  NSHGGFSSNQVINVGLILIA 182


>gi|239754277 PREDICTED: similar to Complement component 4A (Rodgers
           blood group) [Homo sapiens]
          Length = 270

 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 43/143 (30%), Positives = 72/143 (50%), Gaps = 11/143 (7%)

Query: 123 FVQTDKPLYTPGQQVYFRIVTMDSNFVPVNDKYSMVELQDPNSNRIAQWLEVVPEQGIVD 182
           F+QTD+P+Y PGQ+V +R+  +D    P  D  + V +++ +  R+ +  EV     I  
Sbjct: 62  FLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRK-KEVYMPSSIFQ 119

Query: 183 LSFQLAPEAMLGTYTVAV-----AEGKTFGTFSVEEYVLPKFKVEVVEPKE-LSTVQ--- 233
             F +   +  GT+ ++       E  +   F V++YVLP F+V++   K  + TV    
Sbjct: 120 DDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHL 179

Query: 234 ESFLVKICCRYTYGKPMLGAVQV 256
           +   + I  RY YGKP+ G   V
Sbjct: 180 DEMQLDIQARYIYGKPVQGVAYV 202


>gi|169205183 PREDICTED: similar to hCG38149 [Homo sapiens]
          Length = 95

 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 32/87 (36%), Positives = 49/87 (56%)

Query: 1364 MAIVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSV 1423
            M +++VKMLSGF+P   + + L  +  V K E   D +  YL+       ++ F++ QS 
Sbjct: 1    MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60

Query: 1424 LVTNLKPATIKVYDYYLPDEQATIQYS 1450
            LV N++PA   VYDYY  +E A   Y+
Sbjct: 61   LVFNIQPAPAMVYDYYEKEEYALAFYN 87


>gi|239744557 PREDICTED: hypothetical protein LOC728715 [Homo sapiens]
          Length = 95

 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 32/87 (36%), Positives = 49/87 (56%)

Query: 1364 MAIVEVKMLSGFSPMEGTNQLLLQQPLVKKVEFGTDTLNIYLDELIKNTQTYTFTISQSV 1423
            M +++VKMLSGF+P   + + L  +  V K E   D +  YL+       ++ F++ QS 
Sbjct: 1    MVVIDVKMLSGFTPTMSSIEELENKGQVMKTEVKNDHVLFYLENGFGRADSFPFSVEQSN 60

Query: 1424 LVTNLKPATIKVYDYYLPDEQATIQYS 1450
            LV N++PA   VYDYY  +E A   Y+
Sbjct: 61   LVFNIQPAPAMVYDYYEKEEYALAFYN 87


>gi|169214179 PREDICTED: similar to complement component 3 [Homo
            sapiens]
          Length = 390

 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 60/225 (26%), Positives = 99/225 (44%), Gaps = 23/225 (10%)

Query: 1243 VALQALAKYATTAYMPSEEINLVVK-----STENFQRTFNIQSVNRLVFQQDTLPNVPGM 1297
            +  QALA+Y   A    +E+NL V       +       + +S + L+  ++T  N    
Sbjct: 1    MVFQALAQYQKDA-PDHQELNLDVSLQLPSRSSKITHRIHWESAS-LLRSEETKENEGFT 58

Query: 1298 YTLEASGQGCVYVQTVLRYNILPPTNMKTFSLSVEIGKARCEQPTSPR----SLTLTIHT 1353
             T E  GQG + V T+             F L V I K   E    P+    ++ L I T
Sbjct: 59   VTAEGKGQGTLSVVTMYHAKAKDQLTCNKFDLKVTI-KPAPETEKRPQDAKNTMILEICT 117

Query: 1354 SYVGSRSSSNMAIVEVKMLSGFSP--------MEGTNQLLLQQPLVKKVEFGTDTLNIYL 1405
             Y G + ++ M+I+++ M++GF+P          G ++ + +  L K      +TL IYL
Sbjct: 118  RYRGDQDAT-MSILDISMMTGFAPDTDDLKQLANGVDRYISKYELDKAFS-DRNTLIIYL 175

Query: 1406 DELIKNTQT-YTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQY 1449
            D++  +      F + Q   V  ++P  +KVY YY  +E  T  Y
Sbjct: 176  DKVSHSEDDCLAFKVHQYFNVELIQPGAVKVYAYYNLEESCTRFY 220


>gi|169217831 PREDICTED: similar to Ovostatin homolog 2 [Homo
           sapiens]
          Length = 136

 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 31/108 (28%), Positives = 48/108 (44%)

Query: 384 NGTFNQTLVTDNNGLAPFTLETSGWNGTDVSLEGKFQMEDLVYNPEQVPRYYQNAYLHLR 443
           N  F     TD NG A F+++TS     + +L+  +   +  Y P  +   Y +A+  + 
Sbjct: 11  NDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKATYVRPESCYLPSWLTPQYLDAHFLVS 70

Query: 444 PFYSTTRSFLGIHRLNGPLKCGQPQEVLVDYYIDPADASPDQEISFSY 491
            FYS T SFL I      L+C   + V V Y ++      D  + F Y
Sbjct: 71  RFYSRTNSFLKIVPEPKQLECNHQKVVTVHYSLNSEAYEDDSNVKFFY 118


>gi|239755754 PREDICTED: ovostatin 2 [Homo sapiens]
          Length = 164

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 22/60 (36%), Positives = 32/60 (53%)

Query: 1391 VKKVEFGTDTLNIYLDELIKNTQTYTFTISQSVLVTNLKPATIKVYDYYLPDEQATIQYS 1450
            V K E   D +  YL+       ++ F++ QS LV N++PA   VYDYY  +E A   Y+
Sbjct: 97   VMKTEVKNDHVLFYLENGFGRADSFPFSVEQSNLVFNIQPAPAMVYDYYEKEEYALAFYN 156


>gi|170172518 microtubule associated monoxygenase, calponin and LIM
            domain containing 3 isoform 3 [Homo sapiens]
          Length = 966

 Score = 33.1 bits (74), Expect = 2.0
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 1/58 (1%)

Query: 1193 DVELTAYALLAQLTKPSLTQKE-IAKATSIVAWLAKQRNAYGGFSSTQDTVVALQALA 1249
            D+ L   +L+   T P LT+ E +A+++ ++ W  +Q + Y G + T  T+     LA
Sbjct: 495  DIHLEMESLVNSRTTPKLTRNESVARSSKLLGWCQRQTDGYAGVNVTDLTMSWKSGLA 552


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,813,739
Number of Sequences: 37866
Number of extensions: 2558806
Number of successful extensions: 5451
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 5198
Number of HSP's gapped (non-prelim): 75
length of query: 1454
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1339
effective length of database: 13,892,928
effective search space: 18602630592
effective search space used: 18602630592
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.