Search of human proteins with 72534658

Search of human proteins with 72534658

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|72534658 interferon-induced protein with tetratricopeptide
repeats 3 [Homo sapiens]
         (490 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542980 interferon-induced protein with tetratricopeptide re...   995   0.0  
gi|72534658 interferon-induced protein with tetratricopeptide re...   995   0.0  
gi|153082755 interferon-induced protein with tetratricopeptide r...   488   e-138
gi|58330892 interferon-induced protein with tetratricopeptide re...   391   e-109
gi|6912630 interferon-induced protein with tetratricopeptide rep...   377   e-104
gi|116534937 interferon-induced protein with tetratricopeptide r...   363   e-100
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]       61   3e-09
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]       61   3e-09
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]                     45   1e-04
gi|54607135 translocase of outer mitochondrial membrane 70 homol...    43   7e-04
gi|83415184 transmembrane and tetratricopeptide repeat containin...    41   0.003
gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    40   0.004
gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo ...    40   0.004
gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Hom...    40   0.004
gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens]         39   0.008
gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo ...    39   0.014
gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo ...    39   0.014
gi|224809432 transmembrane and tetratricopeptide repeat containi...    38   0.018
gi|118766328 transmembrane and tetratricopeptide repeat containi...    38   0.024
gi|118766330 transmembrane and tetratricopeptide repeat containi...    38   0.024
gi|110611917 tetratricopeptide repeat domain 14 isoform b [Homo ...    37   0.031
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s...    37   0.041
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H...    37   0.053
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H...    37   0.053
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-...    37   0.053
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]       36   0.091
gi|22749211 transmembrane and tetratricopeptide repeat containin...    36   0.091
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       35   0.15 
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    34   0.26 
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    34   0.26 

>gi|31542980 interferon-induced protein with tetratricopeptide
           repeats 3 [Homo sapiens]
          Length = 490

 Score =  995 bits (2573), Expect = 0.0
 Identities = 490/490 (100%), Positives = 490/490 (100%)

Query: 1   MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60
           MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI
Sbjct: 1   MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60

Query: 61  KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120
           KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV
Sbjct: 61  KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120

Query: 121 KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM 180
           KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM
Sbjct: 121 KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM 180

Query: 181 YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ 240
           YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ
Sbjct: 181 YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ 240

Query: 241 TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA 300
           TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA
Sbjct: 241 TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA 300

Query: 301 SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS 360
           SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS
Sbjct: 301 SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS 360

Query: 361 HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL 420
           HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL
Sbjct: 361 HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL 420

Query: 421 QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR 480
           QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR
Sbjct: 421 QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR 480

Query: 481 ELLSNSEQLN 490
           ELLSNSEQLN
Sbjct: 481 ELLSNSEQLN 490


>gi|72534658 interferon-induced protein with tetratricopeptide
           repeats 3 [Homo sapiens]
          Length = 490

 Score =  995 bits (2573), Expect = 0.0
 Identities = 490/490 (100%), Positives = 490/490 (100%)

Query: 1   MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60
           MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI
Sbjct: 1   MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60

Query: 61  KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120
           KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV
Sbjct: 61  KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120

Query: 121 KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM 180
           KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM
Sbjct: 121 KQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAM 180

Query: 181 YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ 240
           YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ
Sbjct: 181 YHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQ 240

Query: 241 TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA 300
           TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA
Sbjct: 241 TDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA 300

Query: 301 SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS 360
           SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS
Sbjct: 301 SGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQS 360

Query: 361 HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL 420
           HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL
Sbjct: 361 HQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPNYWYL 420

Query: 421 QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR 480
           QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR
Sbjct: 421 QGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPR 480

Query: 481 ELLSNSEQLN 490
           ELLSNSEQLN
Sbjct: 481 ELLSNSEQLN 490


>gi|153082755 interferon-induced protein with tetratricopeptide
           repeats 2 [Homo sapiens]
          Length = 472

 Score =  488 bits (1255), Expect = e-138
 Identities = 270/472 (57%), Positives = 330/472 (69%), Gaps = 19/472 (4%)

Query: 1   MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60
           MSE  KNSLE  L QLKCHFTWNL + ++   D ED+V  + EF N EFKATM NLLAY+
Sbjct: 1   MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYL 60

Query: 61  KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120
           KHL G NEAALECLR+AEELIQQEHADQAEIRSLVTWGNYAWVYYH+GRLSD QIYVDKV
Sbjct: 61  KHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKV 120

Query: 121 KQTCKKFSNPYSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSGLAI 178
           K  C+KFS+PY IE  ELDCEEGWT+LKCG  +NERAKVCFEKALE+KP NPEF+SGLAI
Sbjct: 121 KHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAI 180

Query: 179 AMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKM----NKEAEGEQFVEEAL 234
           A Y LDN P  Q + D L+QAI L+PDNQY+KVLL LKL KM     +E EGE+ VEEAL
Sbjct: 181 ASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEAL 240

Query: 235 EKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQN 294
           EK+P  TDVLRSAAKFYRRK + DKAIEL ++ LE  PNN YL+ QIGCCY+AKV Q+ N
Sbjct: 241 EKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMN 300

Query: 295 TGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLA-------EFLETECY-QT 346
             E+   G ++++E L  +A+ +  KA E   N     S LA       ++ + E Y Q 
Sbjct: 301 LRENGMYGKRKLLE-LIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQK 359

Query: 347 PFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVS 406
            F+KE+    KQ  H RY N Q Y  K ED A+ H +EG+ I++KS +KE++KD+ Q ++
Sbjct: 360 EFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIA 419

Query: 407 ENLLPQNAPNYWYLQGL--IHKQNGDLLQAAKCYEK--ELGRLLRDAPSGIG 454
           +  L +N  +   L  L  + + N  + QA +  E+  E G L+  A S  G
Sbjct: 420 KMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNG 471


>gi|58330892 interferon-induced protein with tetratricopeptide
           repeats 1-like [Homo sapiens]
          Length = 474

 Score =  391 bits (1004), Expect = e-109
 Identities = 217/470 (46%), Positives = 301/470 (64%), Gaps = 23/470 (4%)

Query: 1   MSEVTKNSL-EKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAY 59
           MSE +   L E  L QL+CHFTW L  E     DLE+R+  +I+FL+T++   ++NLLAY
Sbjct: 1   MSEESDGKLIEDSLIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAY 60

Query: 60  IKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDK 119
           +KHL G NE AL  L++AE+LIQ+EHA+QA+IRSLVTWGN+AWVYYH+GRL++AQ Y+DK
Sbjct: 61  VKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDK 120

Query: 120 VKQTCKKFSNP--YSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSG 175
           V+ TCKKF+NP  Y +E  E+DCEEGW   KCG    ERAK CFEKALE  P NPEF++G
Sbjct: 121 VENTCKKFANPSRYRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTG 180

Query: 176 LAIAMYHLD-----NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFV 230
            AI +Y LD     +   K FS  VLK+A+ L+PD+ Y++VLL LKLQ   +EAEGE+++
Sbjct: 181 YAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYI 240

Query: 231 EEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVR 290
           EEAL     Q  V + AAKFYRRKG +DKA+EL +  LE+TP + +L+HQ+G CY+A++ 
Sbjct: 241 EEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMI 300

Query: 291 QMQNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFL--------ET 341
           Q++     +  G ++E ++ L Q A+    K +        AY DLAE            
Sbjct: 301 QIKEATNWQPRGQDRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAE 360

Query: 342 ECYQTPFNKEV-PDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKD 400
           E +Q     ++  D  KQ+ H  Y   Q+++GKS+D A+ H L+GL I K S  +E++ +
Sbjct: 361 EHFQKGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLN 420

Query: 401 QPQNVSENLLPQN--APNYWYLQGLIHKQNGDLLQAAKCYEKELGRLLRD 448
             + +++  + QN        L GLIHK  G++  A  CYE+ L RL  D
Sbjct: 421 ALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERAL-RLAAD 469


>gi|6912630 interferon-induced protein with tetratricopeptide
           repeats 5 [Homo sapiens]
          Length = 482

 Score =  377 bits (968), Expect = e-104
 Identities = 205/460 (44%), Positives = 291/460 (63%), Gaps = 20/460 (4%)

Query: 1   MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYI 60
           MSE+ K++L+ IL +L+CHFTWNL KED    ++ED +  Q+EFL T+ +  +YNLLAY+
Sbjct: 1   MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYV 60

Query: 61  KHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKV 120
           KHL G N+ ALECL QAEE+IQQEH+D+ E+RSLVTWGNYAWVYYH+ +L +AQ Y  K+
Sbjct: 61  KHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKI 120

Query: 121 KQTCKKFSNP--YSIEYSELDCEEGWTQLKCGRN--ERAKVCFEKALEEKPNNPEFSSGL 176
              CKK S+P  Y +E  E DCE+GW  LK G    ++AK  FEKALE +P+NPEF+ G 
Sbjct: 121 GNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGY 180

Query: 177 AIAMYHLDNHPE----KQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEE 232
           AI +Y LD+       K FS   L++A+ L+PDN Y+KV L LKLQ ++ EAEGE+++EE
Sbjct: 181 AITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEE 240

Query: 233 ALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQM 292
            L++   Q  VLR AAKFYRRK   +KA+EL ++ LE TP + +L+HQ+G CY+A++ Q+
Sbjct: 241 ILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQI 300

Query: 293 QNTGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE-FLETECYQTP--- 347
           +    +   G +K  ++ L   A+ +   A+E+      AY+DLA  + E   Y      
Sbjct: 301 KKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDI 360

Query: 348 FNK-----EVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQP 402
           F K      + D  K Q H  Y   Q+++ KSE+TA+ H LE L +  +S  + ++    
Sbjct: 361 FRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL 420

Query: 403 QNVSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEK 440
           + +S   L  NA +   L   G ++K  G+  QAA+ YEK
Sbjct: 421 KKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEK 460


>gi|116534937 interferon-induced protein with tetratricopeptide
           repeats 1 isoform 2 [Homo sapiens]
          Length = 478

 Score =  363 bits (933), Expect = e-100
 Identities = 207/471 (43%), Positives = 292/471 (61%), Gaps = 30/471 (6%)

Query: 6   KNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDG 65
           K+SLE    QL+CHFTW L  +D    DLE+RV +QIEFL+T++   ++NLLAY+KHL G
Sbjct: 11  KDSLE----QLRCHFTWELSIDDDEMPDLENRVLDQIEFLDTKYSVGIHNLLAYVKHLKG 66

Query: 66  NNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCK 125
            NE AL+ L++AE L+Q+EH +QA +RSLVTWGN+AW+YYH+GRL++AQ Y+DKV+  CK
Sbjct: 67  QNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICK 126

Query: 126 KFSNP--YSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSGLAIAMY 181
           K SNP  Y +E  E+DCEEGW  LKCG    ERAK CFEK LE  P NPE S+G AI+ Y
Sbjct: 127 KLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAY 186

Query: 182 HLD-------NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEAL 234
            LD       NH  K FS   L+QA+ L+PDN Y+KVLL LKLQ   +EAEGE+++EEAL
Sbjct: 187 RLDGFKLATKNH--KPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEAL 244

Query: 235 EKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQN 294
                QT V R AAKFYRRKG +DKA+EL ++ L+ TP +  L+HQIG CYKA++ Q++ 
Sbjct: 245 ANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKE 304

Query: 295 TGESEASG-NKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEF---------LETECY 344
             + +  G N+E ++ + + A+ +   A+EK      A+ DLA            E    
Sbjct: 305 ATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQ 364

Query: 345 QTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQN 404
           +    K V +   Q  H  Y   Q++  KS+  A+ H L+ + I + S  +++  +  + 
Sbjct: 365 KLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKK 424

Query: 405 VSENLLPQNAPNYWYLQ--GLIHKQNGDLLQAAKCYEKELGRLLRDAPSGI 453
           +    L + A +   L   G ++K  G++ +A + YE+ L RL  D  + +
Sbjct: 425 LVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERAL-RLAADFENSV 474


>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
          Length = 1036

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 75/322 (23%), Positives = 124/322 (38%), Gaps = 30/322 (9%)

Query: 58  AYIKHLDGNNEAALECLRQ-----AEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSD 112
           AY+  L  N +  L C+R       + L + E A    ++++ T  N+A  + +LG + +
Sbjct: 135 AYVSALQYNPD--LYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFN 192

Query: 113 AQIYVDKVKQTCKKFSNPYSIEYSELDC--EEGWTQLKCGRNERAKVCFEKALEEKPNNP 170
           AQ    ++      F    +++ + LD     G    +    +RA   + +AL   PN+ 
Sbjct: 193 AQ---GEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHA 249

Query: 171 EFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFV 230
                LA   Y          + D  ++AIEL P        L   L++    AE E   
Sbjct: 250 VVHGNLACVYYE---QGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCY 306

Query: 231 EEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVR 290
             AL   P   D L + A   R +G++++A+ L+++ LE  P     +  +     A V 
Sbjct: 307 NTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNL-----ASVL 361

Query: 291 QMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNK 350
           Q Q   +      KE I     +A  YSN       N L    D+   L+        N 
Sbjct: 362 QQQGKLQEALMHYKEAIRISPTFADAYSNMG-----NTLKEMQDVQGALQCYTRAIQINP 416

Query: 351 EVPDAEKQQSHQRYCNLQKYNG 372
              DA     H    ++ K +G
Sbjct: 417 AFADA-----HSNLASIHKDSG 433



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 51/234 (21%), Positives = 94/234 (40%), Gaps = 20/234 (8%)

Query: 51  ATMYNLLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRL 110
           A ++  LA + +  G  + A++  R+A EL  Q H   A       + N A      G +
Sbjct: 249 AVVHGNLACVYYEQGLIDLAIDTYRRAIEL--QPHFPDA-------YCNLANALKEKGSV 299

Query: 111 SDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNP 170
           ++A+   +   + C   ++  +   + +  E+G         E A   + KALE  P   
Sbjct: 300 AEAEDCYNTALRLCPTHADSLN-NLANIKREQG-------NIEEAVRLYRKALEVFPEFA 351

Query: 171 EFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFV 230
              S LA     L    + Q +    K+AI +SP        +G  L++M       Q  
Sbjct: 352 AAHSNLASV---LQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCY 408

Query: 231 EEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCC 284
             A++ +P   D   + A  ++  G++ +AI  ++  L+  P+    Y  +  C
Sbjct: 409 TRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 462


>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
          Length = 1046

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 75/322 (23%), Positives = 124/322 (38%), Gaps = 30/322 (9%)

Query: 58  AYIKHLDGNNEAALECLRQ-----AEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSD 112
           AY+  L  N +  L C+R       + L + E A    ++++ T  N+A  + +LG + +
Sbjct: 145 AYVSALQYNPD--LYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFN 202

Query: 113 AQIYVDKVKQTCKKFSNPYSIEYSELDC--EEGWTQLKCGRNERAKVCFEKALEEKPNNP 170
           AQ    ++      F    +++ + LD     G    +    +RA   + +AL   PN+ 
Sbjct: 203 AQ---GEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHA 259

Query: 171 EFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFV 230
                LA   Y          + D  ++AIEL P        L   L++    AE E   
Sbjct: 260 VVHGNLACVYYE---QGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCY 316

Query: 231 EEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVR 290
             AL   P   D L + A   R +G++++A+ L+++ LE  P     +  +     A V 
Sbjct: 317 NTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNL-----ASVL 371

Query: 291 QMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNK 350
           Q Q   +      KE I     +A  YSN       N L    D+   L+        N 
Sbjct: 372 QQQGKLQEALMHYKEAIRISPTFADAYSNMG-----NTLKEMQDVQGALQCYTRAIQINP 426

Query: 351 EVPDAEKQQSHQRYCNLQKYNG 372
              DA     H    ++ K +G
Sbjct: 427 AFADA-----HSNLASIHKDSG 443



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 51/234 (21%), Positives = 94/234 (40%), Gaps = 20/234 (8%)

Query: 51  ATMYNLLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRL 110
           A ++  LA + +  G  + A++  R+A EL  Q H   A       + N A      G +
Sbjct: 259 AVVHGNLACVYYEQGLIDLAIDTYRRAIEL--QPHFPDA-------YCNLANALKEKGSV 309

Query: 111 SDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNP 170
           ++A+   +   + C   ++  +   + +  E+G         E A   + KALE  P   
Sbjct: 310 AEAEDCYNTALRLCPTHADSLN-NLANIKREQG-------NIEEAVRLYRKALEVFPEFA 361

Query: 171 EFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFV 230
              S LA     L    + Q +    K+AI +SP        +G  L++M       Q  
Sbjct: 362 AAHSNLASV---LQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCY 418

Query: 231 EEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCC 284
             A++ +P   D   + A  ++  G++ +AI  ++  L+  P+    Y  +  C
Sbjct: 419 TRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHC 472


>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
          Length = 519

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 25/95 (26%), Positives = 46/95 (48%)

Query: 194 DVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRR 253
           +V K+A+E SP+N  +   LGL   ++    +  + +  AL   P     + +A    + 
Sbjct: 189 EVYKKAVEFSPENTELLTTLGLLYLQLGIYQKAFEHLGNALTYDPTNYKAILAAGSMMQT 248

Query: 254 KGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAK 288
            GD D A+  ++ V  + P +  L++ IG C+  K
Sbjct: 249 HGDFDVALTKYRVVACAVPESPPLWNNIGMCFFGK 283



 Score = 36.6 bits (83), Expect = 0.053
 Identities = 32/145 (22%), Positives = 66/145 (45%), Gaps = 11/145 (7%)

Query: 150 GRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYV 209
           G  + +   F+      P + +    +A +++ L  H   + + +V  +A +L+  +  +
Sbjct: 81  GNIQESLELFQTCAVLSPQSADNLKQVARSLFLLGKH---KAAIEVYNEAAKLNQKDWEI 137

Query: 210 KVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLE 269
              LG+    + +  + +  +  AL  +      +    K +  +GDLDKAIE++++ +E
Sbjct: 138 SHNLGVCYIYLKQFNKAQDQLHNALNLNRHDLTYIM-LGKIHLLEGDLDKAIEVYKKAVE 196

Query: 270 STPNN-------GYLYHQIGCCYKA 287
            +P N       G LY Q+G   KA
Sbjct: 197 FSPENTELLTTLGLLYLQLGIYQKA 221


>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
           A [Homo sapiens]
          Length = 608

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 42/189 (22%), Positives = 76/189 (40%), Gaps = 10/189 (5%)

Query: 103 VYYHLGRLSDAQIYVDKVKQTCKKFSN-----PYSIEYSELDCEEGWTQLKCGRNERAKV 157
           VY+H G+L   +I +D+V++    F       P S       C   + Q   G N     
Sbjct: 403 VYHHRGQL---KILLDQVEEAVADFDECIRLRPESALAQAQKCFALYRQAYTGNNSSQIQ 459

Query: 158 CFEKALEEKPNN-PEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLG-L 215
              K  EE     P  + G A+    L +  +   + ++  + I+L PDN    V  G L
Sbjct: 460 AAMKGFEEVIKKFPRCAEGYALYAQALTDQQQFGKADEMYDKCIDLEPDNATTYVHKGLL 519

Query: 216 KLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNG 275
           +LQ       G + + +A+E          +      ++G+++KAI++F + +    +  
Sbjct: 520 QLQWKQDLDRGLELISKAIEIDNKCDFAYETMGTIEVQRGNMEKAIDMFNKAINLAKSEM 579

Query: 276 YLYHQIGCC 284
            + H    C
Sbjct: 580 EMAHLYSLC 588


>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
           [Homo sapiens]
          Length = 774

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 52/269 (19%), Positives = 112/269 (41%), Gaps = 22/269 (8%)

Query: 20  FTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDGNNEAALECLRQAEE 79
           F+W   K++ +    E    + ++ L    K   YN   ++K   G N+ A+   R A +
Sbjct: 346 FSWKTVKQNEIWLSRESLFRSGVQTLPHNAKVH-YNYANFLKD-QGRNKEAIYHYRTALK 403

Query: 80  LIQQEHADQAEIRSLVTWGNYAWVYY---------------HLGRLSDAQIYVDKVKQTC 124
           L  +  +    + +L      A +YY               +LG L  +Q   ++   T 
Sbjct: 404 LYPRHASALNNLGTLTRDTAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKKEEAI-TL 462

Query: 125 KKFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLD 184
            K S  Y  E+++          +  R + A+  ++  ++  P++ +  +   + +    
Sbjct: 463 LKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNYGVFLVDT- 521

Query: 185 NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVL 244
             PEK  +    +QAI+LSP +    V LG   + + + +  E++ + AL+ +  + ++L
Sbjct: 522 GLPEKAVAH--YQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAH-KAEIL 578

Query: 245 RSAAKFYRRKGDLDKAIELFQRVLESTPN 273
                 Y   G  ++A++++Q      P+
Sbjct: 579 SPLGALYYNTGRYEEALQIYQEAAALQPS 607



 Score = 30.8 bits (68), Expect = 2.9
 Identities = 50/223 (22%), Positives = 89/223 (39%), Gaps = 26/223 (11%)

Query: 45  LNTEFKATMYNLLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVY 104
           L    KA + + L  + +  G  E AL+  ++A  L       Q E+R  +     A V 
Sbjct: 569 LQVAHKAEILSPLGALYYNTGRYEEALQIYQEAAAL----QPSQRELRLAL-----AQVL 619

Query: 105 YHLGRLSDAQIYVDKVKQTCKKFSNPYSIEYSELDCEEGWTQL--KCGRNERAKVCFEKA 162
             +G+  +A+          K  ++  S E   L+C    + +  K   +++A    +KA
Sbjct: 620 AVMGQTKEAE----------KMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKA 669

Query: 163 LEEKPNNPEFSSGLAIA---MYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQK 219
           L+ KP +P+  S L           N  +K F +   + A++L+PD     + +G     
Sbjct: 670 LQLKPKDPKVISELFFTKGNQLREQNLLDKAFES--YRVAVQLNPDQAQAWMNMGGIQHI 727

Query: 220 MNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE 262
             K      + E AL+  P    +  + AK  R +  L +  E
Sbjct: 728 KGKYVSARAYYERALQLVPDSKLLKENLAKLDRLEKRLQEVRE 770


>gi|239756104 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 5/122 (4%)

Query: 169  NPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQ 228
            NP++S     A     +H +   ++D   +A++  P+N+YV +   +    + K  E ++
Sbjct: 1472 NPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKE 1531

Query: 229  FVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAK 288
                 +E  P    V  + A FY      + A E   + L   PN+  +Y+     ++AK
Sbjct: 1532 DFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN-----FRAK 1586

Query: 289  VR 290
            VR
Sbjct: 1587 VR 1588



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 24/100 (24%), Positives = 51/100 (51%), Gaps = 6/100 (6%)

Query: 190  QFSTDVLKQAIELSP---DNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRS 246
            Q + + L++ I L P   +  + + L+ L   K+N+  +   ++ +  + +   T+   S
Sbjct: 934  QSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNN---TEAYLS 990

Query: 247  AAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYK 286
             A+ YR K D+  AI  + + ++STP +  +Y + G  Y+
Sbjct: 991  KAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYE 1030


>gi|239750633 PREDICTED: tetratricopeptide repeat domain 6 [Homo
            sapiens]
          Length = 1614

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 5/122 (4%)

Query: 169  NPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQ 228
            NP++S     A     +H +   ++D   +A++  P+N+YV +   +    + K  E ++
Sbjct: 1472 NPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKE 1531

Query: 229  FVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAK 288
                 +E  P    V  + A FY      + A E   + L   PN+  +Y+     ++AK
Sbjct: 1532 DFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN-----FRAK 1586

Query: 289  VR 290
            VR
Sbjct: 1587 VR 1588



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 24/100 (24%), Positives = 51/100 (51%), Gaps = 6/100 (6%)

Query: 190  QFSTDVLKQAIELSP---DNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRS 246
            Q + + L++ I L P   +  + + L+ L   K+N+  +   ++ +  + +   T+   S
Sbjct: 934  QSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNN---TEAYLS 990

Query: 247  AAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYK 286
             A+ YR K D+  AI  + + ++STP +  +Y + G  Y+
Sbjct: 991  KAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYE 1030


>gi|239744942 PREDICTED: chromosome 14 open reading frame 25 [Homo
            sapiens]
          Length = 1614

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 5/122 (4%)

Query: 169  NPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQ 228
            NP++S     A     +H +   ++D   +A++  P+N+YV +   +    + K  E ++
Sbjct: 1472 NPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKE 1531

Query: 229  FVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAK 288
                 +E  P    V  + A FY      + A E   + L   PN+  +Y+     ++AK
Sbjct: 1532 DFANVIESCPFWAAVYFNRAHFYYCLKQYELAEEDLNKALSLKPNDALVYN-----FRAK 1586

Query: 289  VR 290
            VR
Sbjct: 1587 VR 1588



 Score = 31.2 bits (69), Expect = 2.2
 Identities = 24/100 (24%), Positives = 51/100 (51%), Gaps = 6/100 (6%)

Query: 190  QFSTDVLKQAIELSP---DNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRS 246
            Q + + L++ I L P   +  + + L+ L   K+N+  +   ++ +  + +   T+   S
Sbjct: 934  QSAMNDLQRVILLEPLFLNAYWHRHLIYLFQDKINEALDDLNYIHKYNKNN---TEAYLS 990

Query: 247  AAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYK 286
             A+ YR K D+  AI  + + ++STP +  +Y + G  Y+
Sbjct: 991  KAEIYRGKKDITLAILNYTQAIKSTPTDADIYFRRGEMYE 1030


>gi|7706671 peroxisomal biogenesis factor 5-like [Homo sapiens]
          Length = 626

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 36/163 (22%), Positives = 64/163 (39%), Gaps = 37/163 (22%)

Query: 143 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL 202
           G TQ +    + A V  ++ LE +PNN +    LA++     N   +Q + D LK  I+ 
Sbjct: 367 GITQAENENEQAAIVALQRCLELQPNNLKALMALAVS---YTNTGHQQDACDALKNWIKQ 423

Query: 203 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFY----------- 251
           +P  +Y           + K  +G   +   + KSP  + VL    + Y           
Sbjct: 424 NPKYKY-----------LVKSKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDMI 472

Query: 252 ------------RRKGDLDKAIELFQRVLESTPNNGYLYHQIG 282
                          G+ ++AI+ F   L   P +  L++++G
Sbjct: 473 DPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLG 515


>gi|28558993 intraflagellar transport 88 homolog isoform 1 [Homo
           sapiens]
          Length = 833

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 3/144 (2%)

Query: 143 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL 202
           G T  K  R + A  CF K      N+ E    +A  +Y L  +P +  + + L Q + +
Sbjct: 534 GLTYEKLNRLDEALDCFLKLHAILRNSAEVLYQIA-NIYELMENPSQ--AIEWLMQVVSV 590

Query: 203 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE 262
            P +  V   LG    +   +++  Q+  E+    PC  +V+     +Y      +KAI+
Sbjct: 591 IPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQ 650

Query: 263 LFQRVLESTPNNGYLYHQIGCCYK 286
            F+R     P        +  C++
Sbjct: 651 YFERASLIQPTQVKWQLMVASCFR 674


>gi|28329439 intraflagellar transport 88 homolog isoform 2 [Homo
           sapiens]
          Length = 824

 Score = 38.5 bits (88), Expect = 0.014
 Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 3/144 (2%)

Query: 143 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL 202
           G T  K  R + A  CF K      N+ E    +A  +Y L  +P +  + + L Q + +
Sbjct: 525 GLTYEKLNRLDEALDCFLKLHAILRNSAEVLYQIA-NIYELMENPSQ--AIEWLMQVVSV 581

Query: 203 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE 262
            P +  V   LG    +   +++  Q+  E+    PC  +V+     +Y      +KAI+
Sbjct: 582 IPTDPQVLSKLGELYDREGDKSQAFQYYYESYRYFPCNIEVIEWLGAYYIDTQFWEKAIQ 641

Query: 263 LFQRVLESTPNNGYLYHQIGCCYK 286
            F+R     P        +  C++
Sbjct: 642 YFERASLIQPTQVKWQLMVASCFR 665


>gi|224809432 transmembrane and tetratricopeptide repeat containing
           3 [Homo sapiens]
          Length = 914

 Score = 38.1 bits (87), Expect = 0.018
 Identities = 29/132 (21%), Positives = 56/132 (42%), Gaps = 5/132 (3%)

Query: 185 NHPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVL 244
           N    + +  + +QAI + PD +   +  G  L KMNK  + ++   +ALE      D+ 
Sbjct: 541 NESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRNNADLW 600

Query: 245 RSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEASGNK 304
            + A  +    + ++A++ F R LE  P      H++     A V Q     +      K
Sbjct: 601 YNLAIVHIELKEPNEALKNFNRALELNPK-----HKLALFNSAIVMQESGEVKLRPEARK 655

Query: 305 EMIEALKQYAMD 316
            ++  + +  +D
Sbjct: 656 RLLSYINEEPLD 667



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 1/91 (1%)

Query: 196 LKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTD-VLRSAAKFYRRK 254
           +K+AI+L  D +     L L   +  KE +    +EE L   P     ++        +K
Sbjct: 691 MKKAIKLQADFRSALFNLALLYSQTAKELKALPILEELLRYYPDHIKGLILKGDILMNQK 750

Query: 255 GDLDKAIELFQRVLESTPNNGYLYHQIGCCY 285
            D+  A + F+R+LE  P+N    H +   Y
Sbjct: 751 KDILGAKKCFERILEMDPSNVQGKHNLCVVY 781



 Score = 29.3 bits (64), Expect = 8.5
 Identities = 18/72 (25%), Positives = 34/72 (47%), Gaps = 7/72 (9%)

Query: 155 AKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQF--STDVLKQAIELSPDNQYVKVL 212
           AK CFE+ LE  P+N +    L +  +      EK    +   L + + L+P  +Y++  
Sbjct: 756 AKKCFERILEMDPSNVQGKHNLCVVYFE-----EKDLLKAERCLLETLALAPHEEYIQRH 810

Query: 213 LGLKLQKMNKEA 224
           L +   K++  +
Sbjct: 811 LNIVRDKISSSS 822


>gi|118766328 transmembrane and tetratricopeptide repeat containing
           4 isoform 2 [Homo sapiens]
          Length = 741

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 62/257 (24%), Positives = 93/257 (36%), Gaps = 23/257 (8%)

Query: 17  KCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDGNNEAALECLRQ 76
           K H+       D  ++    R   +   LN ++   M NL   +K     NE     L++
Sbjct: 483 KVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE---RNE-----LQE 534

Query: 77  AEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDA-QIYVDKVKQTCKKFSNPYSIEY 135
           AEEL+    A Q +      W N   V   L R   A Q Y   +K   K     Y++  
Sbjct: 535 AEELLSL--AVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGR 592

Query: 136 SELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDV 195
              D       L   RN                 PE S      +  LDN      +  V
Sbjct: 593 LYADLNRHVDALNAWRNATVL------------KPEHSLAWNNMIILLDNTGNLAQAEAV 640

Query: 196 LKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKG 255
            ++A+EL P++  +   L   L K  K  E E    +A++ +P       + A  Y R G
Sbjct: 641 GREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWG 700

Query: 256 DLDKAIELFQRVLESTP 272
            LD A + ++  L+  P
Sbjct: 701 HLDLAKKHYEISLQLDP 717



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 39/178 (21%), Positives = 70/178 (39%), Gaps = 11/178 (6%)

Query: 143 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL 202
           G  Q    R E A+  +  A++ +   P+    L      L+ H +   + +  + A  L
Sbjct: 557 GIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVD---ALNAWRNATVL 613

Query: 203 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE 262
            P++      + + L      A+ E    EALE  P    ++ S A    +     ++  
Sbjct: 614 KPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEA 673

Query: 263 LFQRVLESTPNN-------GYLYHQIGCCYKAKVR-QMQNTGESEASGNKEMIEALKQ 312
           LF + +++ PN          LYH+ G    AK   ++    +  ASG KE    L++
Sbjct: 674 LFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRR 731


>gi|118766330 transmembrane and tetratricopeptide repeat containing
           4 isoform 1 [Homo sapiens]
          Length = 760

 Score = 37.7 bits (86), Expect = 0.024
 Identities = 62/257 (24%), Positives = 93/257 (36%), Gaps = 23/257 (8%)

Query: 17  KCHFTWNLFKEDSVSRDLEDRVCNQIEFLNTEFKATMYNLLAYIKHLDGNNEAALECLRQ 76
           K H+       D  ++    R   +   LN ++   M NL   +K     NE     L++
Sbjct: 502 KVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE---RNE-----LQE 553

Query: 77  AEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDA-QIYVDKVKQTCKKFSNPYSIEY 135
           AEEL+    A Q +      W N   V   L R   A Q Y   +K   K     Y++  
Sbjct: 554 AEELLSL--AVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGR 611

Query: 136 SELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDV 195
              D       L   RN                 PE S      +  LDN      +  V
Sbjct: 612 LYADLNRHVDALNAWRNATVL------------KPEHSLAWNNMIILLDNTGNLAQAEAV 659

Query: 196 LKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKG 255
            ++A+EL P++  +   L   L K  K  E E    +A++ +P       + A  Y R G
Sbjct: 660 GREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWG 719

Query: 256 DLDKAIELFQRVLESTP 272
            LD A + ++  L+  P
Sbjct: 720 HLDLAKKHYEISLQLDP 736



 Score = 33.1 bits (74), Expect = 0.59
 Identities = 39/178 (21%), Positives = 70/178 (39%), Gaps = 11/178 (6%)

Query: 143 GWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIEL 202
           G  Q    R E A+  +  A++ +   P+    L      L+ H +   + +  + A  L
Sbjct: 576 GIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVD---ALNAWRNATVL 632

Query: 203 SPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIE 262
            P++      + + L      A+ E    EALE  P    ++ S A    +     ++  
Sbjct: 633 KPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEA 692

Query: 263 LFQRVLESTPNN-------GYLYHQIGCCYKAKVR-QMQNTGESEASGNKEMIEALKQ 312
           LF + +++ PN          LYH+ G    AK   ++    +  ASG KE    L++
Sbjct: 693 LFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGLLRR 750


>gi|110611917 tetratricopeptide repeat domain 14 isoform b [Homo
           sapiens]
          Length = 439

 Score = 37.4 bits (85), Expect = 0.031
 Identities = 44/185 (23%), Positives = 69/185 (37%), Gaps = 16/185 (8%)

Query: 160 EKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVK--VLLGLKL 217
           EK   ++ N P    GL            K FS D    A+       +    V +G+  
Sbjct: 268 EKLGIDESNPPSLMRGLQ----------SKNFSEDDFASALRKKQSASWALKCVKIGVDY 317

Query: 218 QKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYL 277
            K+ +  +      +ALE      + L +    Y  KG L+KAIE F+  LE+ P +   
Sbjct: 318 FKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNA 377

Query: 278 YHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE 337
              +      +  Q++   E E   N E     K  A+D + K  E  L  L+ Y  +  
Sbjct: 378 RKYLCQTLVERGGQLE---EEEKFLNAESYYK-KALALDETFKDAEDALQKLHKYMQVIP 433

Query: 338 FLETE 342
           +   E
Sbjct: 434 YFLLE 438


>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
           sapiens]
          Length = 770

 Score = 37.0 bits (84), Expect = 0.041
 Identities = 57/251 (22%), Positives = 93/251 (37%), Gaps = 26/251 (10%)

Query: 160 EKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIELSPDNQYVK--VLLGLKL 217
           EK   ++ N P    GL            K FS D    A+       +    V +G+  
Sbjct: 268 EKLGIDESNPPSLMRGLQ----------SKNFSEDDFASALRKKQSASWALKCVKIGVDY 317

Query: 218 QKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYL 277
            K+ +  +      +ALE      + L +    Y  KG L+KAIE F+  LE+ P +   
Sbjct: 318 FKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNA 377

Query: 278 YHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLAE 337
              +      +  Q++   E E   N E     K  A+D + K  E  L  L+ Y  + +
Sbjct: 378 RKYLCQTLVERGGQLE---EEEKFLNAESYYK-KALALDETFKDAEDALQKLHKY--MQK 431

Query: 338 FLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNG--KSEDTAVQHGLEGLSISKKSTDK 395
            LE         K+    EKQ++ +   + +K     K E    +   +  S S  S+  
Sbjct: 432 SLELR------EKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSSVSSAD 485

Query: 396 EEIKDQPQNVS 406
           E +     + S
Sbjct: 486 ESVSSSSSSSS 496


>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
           sapiens]
          Length = 631

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 57/253 (22%), Positives = 94/253 (37%), Gaps = 51/253 (20%)

Query: 141 EEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAI 200
           E+G    K G+ + A  C+ K ++  P NP   +  A A + L     K+F+        
Sbjct: 138 EKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL-----KKFAV------- 185

Query: 201 ELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKA 260
                                  AE +  +  AL +S  +    R AA+F  +K  L++A
Sbjct: 186 -----------------------AESDCNLAVALNRSYTKAYSRRGAARFALQK--LEEA 220

Query: 261 IELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA-------SGNKEMIEALKQY 313
            + ++RVLE  PNN    +++    +A +   +N+   EA        G ++ IEA +  
Sbjct: 221 KKDYERVLELEPNNFEATNELRKISQA-LASKENSYPKEADIVIKSTEGERKQIEAQQNK 279

Query: 314 AMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSH-QRYCNLQKYNG 372
               S K    G      Y         ECY      +  +A    +    Y  +QKY  
Sbjct: 280 QQAISEKDRGNGFFKEGKYE-----RAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334

Query: 373 KSEDTAVQHGLEG 385
             +D      L+G
Sbjct: 335 AEKDCTQAILLDG 347


>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 57/253 (22%), Positives = 94/253 (37%), Gaps = 51/253 (20%)

Query: 141 EEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAI 200
           E+G    K G+ + A  C+ K ++  P NP   +  A A + L     K+F+        
Sbjct: 138 EKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRL-----KKFAV------- 185

Query: 201 ELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKA 260
                                  AE +  +  AL +S  +    R AA+F  +K  L++A
Sbjct: 186 -----------------------AESDCNLAVALNRSYTKAYSRRGAARFALQK--LEEA 220

Query: 261 IELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGESEA-------SGNKEMIEALKQY 313
            + ++RVLE  PNN    +++    +A +   +N+   EA        G ++ IEA +  
Sbjct: 221 KKDYERVLELEPNNFEATNELRKISQA-LASKENSYPKEADIVIKSTEGERKQIEAQQNK 279

Query: 314 AMDYSNKALEKGLNPLNAYSDLAEFLETECYQTPFNKEVPDAEKQQSH-QRYCNLQKYNG 372
               S K    G      Y         ECY      +  +A    +    Y  +QKY  
Sbjct: 280 QQAISEKDRGNGFFKEGKYE-----RAIECYTRGIAADGANALLPANRAMAYLKIQKYEE 334

Query: 373 KSEDTAVQHGLEG 385
             +D      L+G
Sbjct: 335 AEKDCTQAILLDG 347


>gi|24308141 small glutamine-rich tetratricopeptide repeat
           (TPR)-containing, beta [Homo sapiens]
          Length = 304

 Score = 36.6 bits (83), Expect = 0.053
 Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 10/117 (8%)

Query: 141 EEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAI 200
           +EG   +K      A  C+ +A+E  PNN  +    A A   L ++      TD +K   
Sbjct: 90  DEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHY------TDAIKDCE 143

Query: 201 E-LSPDNQYVKVL--LGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRK 254
           + ++ D++Y K    +GL L  +NK  E     ++AL+  P + D  +S  K   +K
Sbjct: 144 KAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDP-ENDSYKSNLKIAEQK 199



 Score = 32.7 bits (73), Expect = 0.77
 Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 17/114 (14%)

Query: 66  NNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCK 125
           N  AA++C  QA EL         +  + V + N A     LG  +DA    +K      
Sbjct: 100 NYAAAVDCYTQAIEL---------DPNNAVYYCNRAAAQSKLGHYTDAIKDCEKAIAIDS 150

Query: 126 KFSNPYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIA 179
           K+S  Y           G       + E A   ++KAL+  P N  + S L IA
Sbjct: 151 KYSKAYG--------RMGLALTALNKFEEAVTSYQKALDLDPENDSYKSNLKIA 196


>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
          Length = 313

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 28/97 (28%), Positives = 42/97 (43%), Gaps = 3/97 (3%)

Query: 142 EGWTQLKCGRNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDNHPEKQFSTDVLKQAIE 201
           EG  Q+K    E A   + KA+E  P N  +    A A   L N+     +    ++AI 
Sbjct: 97  EGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAG---AVQDCERAIC 153

Query: 202 LSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSP 238
           + P        +GL L  +NK  E   + ++ALE  P
Sbjct: 154 IDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDP 190


>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
           [Homo sapiens]
          Length = 836

 Score = 35.8 bits (81), Expect = 0.091
 Identities = 49/233 (21%), Positives = 103/233 (44%), Gaps = 23/233 (9%)

Query: 71  LECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDA-QIYVDKVKQTCKKFSN 129
           L+C    +E ++  HA ++ + S +   N   +Y+  G   +A  +Y + +++  ++F+ 
Sbjct: 585 LKCSEIPDENLKDPHAHKSSVTSCLY--NLGKLYHEQGHYEEALSVYKEAIQKMPRQFA- 641

Query: 130 PYSIEYSELDCEEGWTQLKCGRNERAKVCFEKALEEKPNN--PEFSSGLAIAMYHLDNHP 187
           P S+ Y+ +    G   ++  +   A+  + ++L  K ++     + G  +A+    +  
Sbjct: 642 PQSL-YNMM----GEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLTYGKLLALTGRKSEA 696

Query: 188 EKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSA 247
           EK F      +AIEL P      +  G  L +  +  E  +  ++A E    + DV+ +A
Sbjct: 697 EKLFL-----KAIELDPTKGNCYMHYGQFLLEEARLIEAAEMAKKAAELDSTEFDVVFNA 751

Query: 248 AKFYRRKG---DLDKAIELFQRVLESTP----NNGYLYHQIGCCYKAKVRQMQ 293
           A   R+       +K  +L  R+  + P    N G + H  G   KA+   ++
Sbjct: 752 AHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAILHLNGRLQKAEANYLR 804


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 45/186 (24%), Positives = 75/186 (40%), Gaps = 13/186 (6%)

Query: 216 KLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNG 275
           +++   K A  E+   EA E+   + +  R+A +  R K +  +A E  QR+ E      
Sbjct: 294 RIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 353

Query: 276 YLYHQIGCCYKAKVRQMQNTGESEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDL 335
               +I    K    + Q     E    K  +E  K+      NK LE+  + +      
Sbjct: 354 EERQRIKEEEKRAAEERQRARAEEEE--KAKVEEQKR------NKQLEEKKHAMQETKIK 405

Query: 336 AEFLETECYQTPFNKEVPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDK 395
            E +E +      N++    +K Q+      + K  G+ + T VQ   E L   K +  K
Sbjct: 406 GEKVEQKIEGKWVNEKKAQEDKLQTA-----VLKKQGEEKGTKVQAKREKLQEDKPTFKK 460

Query: 396 EEIKDQ 401
           EEIKD+
Sbjct: 461 EEIKDE 466


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform
           5 [Homo sapiens]
          Length = 6907

 Score = 34.3 bits (77), Expect = 0.26
 Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 4/73 (5%)

Query: 190 QFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAK 249
           +FSTD+   ++EL P+N    +  G K +K N+E  G+  V + +EK   Q ++  + AK
Sbjct: 699 EFSTDM---SVEL-PENYNQNIKAGEKHEKENEEFTGQLKVAKDVEKLIGQVEIWEAEAK 754

Query: 250 FYRRKGDLDKAIE 262
               + D+D ++E
Sbjct: 755 SVLDQDDVDTSME 767


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform
           1 [Homo sapiens]
          Length = 6885

 Score = 34.3 bits (77), Expect = 0.26
 Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 4/73 (5%)

Query: 190 QFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAEGEQFVEEALEKSPCQTDVLRSAAK 249
           +FSTD+   ++EL P+N    +  G K +K N+E  G+  V + +EK   Q ++  + AK
Sbjct: 699 EFSTDM---SVEL-PENYNQNIKAGEKHEKENEEFTGQLKVAKDVEKLIGQVEIWEAEAK 754

Query: 250 FYRRKGDLDKAIE 262
               + D+D ++E
Sbjct: 755 SVLDQDDVDTSME 767


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,168,605
Number of Sequences: 37866
Number of extensions: 815605
Number of successful extensions: 2310
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 2144
Number of HSP's gapped (non-prelim): 202
length of query: 490
length of database: 18,247,518
effective HSP length: 106
effective length of query: 384
effective length of database: 14,233,722
effective search space: 5465749248
effective search space used: 5465749248
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.