Search of human proteins with 7019563

Search of human proteins with 7019563

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7019563 testes-specific protease 50 [Homo sapiens]
         (385 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7019563 testes-specific protease 50 [Homo sapiens]                 809   0.0  
gi|4506153 prostasin preproprotein [Homo sapiens]                     156   3e-38
gi|13994276 marapsin [Homo sapiens]                                   153   2e-37
gi|117956391 protease, serine, 33 [Homo sapiens]                      153   2e-37
gi|11545839 protease, serine, 22 [Homo sapiens]                       151   1e-36
gi|5803197 testisin isoform 1 [Homo sapiens]                          147   2e-35
gi|21614531 testisin isoform 2 [Homo sapiens]                         145   5e-35
gi|33695155 hepsin [Homo sapiens]                                     142   4e-34
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             142   4e-34
gi|4504481 hepsin [Homo sapiens]                                      142   4e-34
gi|148806900 epidermis-specific serine protease-like protein [Ho...   141   9e-34
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         140   3e-33
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            139   3e-33
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  136   3e-32
gi|21614533 testisin isoform 3 [Homo sapiens]                         135   8e-32
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]          132   7e-31
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ...   132   7e-31
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ...   132   7e-31
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]      130   2e-30
gi|187761337 transmembrane protease, serine 11B [Homo sapiens]        129   4e-30
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         128   8e-30
gi|34098976 marapsin 2 [Homo sapiens]                                 128   8e-30
gi|4503627 coagulation factor XI precursor [Homo sapiens]             127   1e-29
gi|110815798 ovochymase 1 [Homo sapiens]                              125   6e-29
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   125   8e-29
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   122   4e-28
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   122   4e-28
gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo s...   122   5e-28
gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo ...   122   5e-28
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           122   5e-28

>gi|7019563 testes-specific protease 50 [Homo sapiens]
          Length = 385

 Score =  809 bits (2090), Expect = 0.0
 Identities = 385/385 (100%), Positives = 385/385 (100%)

Query: 1   MGRWCQTVARGQRPRTSAPSRAGALLLLLLLLRSAGCWGAGEAPGALSTADPADQSVQCV 60
           MGRWCQTVARGQRPRTSAPSRAGALLLLLLLLRSAGCWGAGEAPGALSTADPADQSVQCV
Sbjct: 1   MGRWCQTVARGQRPRTSAPSRAGALLLLLLLLRSAGCWGAGEAPGALSTADPADQSVQCV 60

Query: 61  PKATCPSSRPRLLWQTPTTQTLPSTTMETQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAV 120
           PKATCPSSRPRLLWQTPTTQTLPSTTMETQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAV
Sbjct: 61  PKATCPSSRPRLLWQTPTTQTLPSTTMETQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAV 120

Query: 121 ARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQTASD 180
           ARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQTASD
Sbjct: 121 ARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQTASD 180

Query: 181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC 240
           VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC
Sbjct: 181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC 240

Query: 241 TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDT 300
           TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDT
Sbjct: 241 TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDT 300

Query: 301 HREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQ 360
           HREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQ
Sbjct: 301 HREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQ 360

Query: 361 ALALPAPSRTLLLALPLPLSLLAAL 385
           ALALPAPSRTLLLALPLPLSLLAAL
Sbjct: 361 ALALPAPSRTLLLALPLPLSLLAAL 385


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  156 bits (394), Expect = 3e-38
 Identities = 82/238 (34%), Positives = 121/238 (50%), Gaps = 10/238 (4%)

Query: 119 AVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVIYSVRVGSPWIDQMTQ 176
           AVA +WPW VS+   G H+C G++++ QWVL+ AHC         Y V++G+  +D  ++
Sbjct: 51  AVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSE 110

Query: 177 TASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKD 236
            A    +  +I H  Y  +      G   DI LL+L + + +S Y+RPICLP  +    +
Sbjct: 111 DAKVSTLKDIIPHPSYLQE------GSQGDIALLQLSRPITFSRYIRPICLPAANASFPN 164

Query: 237 HSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMC 296
              CTVTGWG           + +Q+ EV +++ + C N  +N    P     ++  M+C
Sbjct: 165 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETC-NCLYNIDAKPEEPHFVQEDMVC 223

Query: 297 AEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
           A      K  C   +G PL C +EG WYL G+VSWG  C     P +Y   SSY  WI
Sbjct: 224 AGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 281


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  153 bits (387), Expect = 2e-37
 Identities = 75/233 (32%), Positives = 127/233 (54%), Gaps = 9/233 (3%)

Query: 124 WPWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVIYSVRVGSPWIDQMTQTASDV 181
           WPW VS++ NG+H C G++IA QWVLT AHC        +Y V +G+  + Q    A   
Sbjct: 46  WPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYA 105

Query: 182 PVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCT 241
            V QV  +  Y+          + D+ L++L+  + ++NY+ P+CLP    + +    C 
Sbjct: 106 RVRQVESNPLYQG------TASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCW 159

Query: 242 VTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAE-DT 300
           VTGWG    + + P+ R +Q+  V I++  +C+  Y   T+     + IK+ M+CA  + 
Sbjct: 160 VTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEE 219

Query: 301 HREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
            ++  C   +G PLVC +  +W   G++SWG GC +   P +Y++V+++ +WI
Sbjct: 220 GKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  153 bits (387), Expect = 2e-37
 Identities = 81/233 (34%), Positives = 120/233 (51%), Gaps = 9/233 (3%)

Query: 124 WPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVI--YSVRVGSPWIDQMTQTASDV 181
           WPW  S++  G H+C G++IA QWVLT AHC   R +   Y VR+G+  +   +     V
Sbjct: 48  WPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSV 107

Query: 182 PVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCT 241
           PV +V++   Y         G   D+ LL+L++ +  S  V+P+CLP         + C 
Sbjct: 108 PVRRVLLPPDYSED------GARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCR 161

Query: 242 VTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTH 301
           VTGWG  +     P++R +Q   V +L+++ CD  YH    +P   +I+    +CA    
Sbjct: 162 VTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQ 221

Query: 302 REK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
             K  C   +G PL C   G+W LVG+VSWG GC     P +Y  V++Y  WI
Sbjct: 222 GHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274


>gi|11545839 protease, serine, 22 [Homo sapiens]
          Length = 317

 Score =  151 bits (381), Expect = 1e-36
 Identities = 84/280 (30%), Positives = 147/280 (52%), Gaps = 23/280 (8%)

Query: 103 SCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCL---IWRD 159
           +CG   + +  +   ++    WPW+VS++ NGTH CAG+++ S+WV+T AHC    + + 
Sbjct: 40  ACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKP 99

Query: 160 VIYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSW-VGQANDIGLLKLKQELKY 218
            ++SV +G+  +      +  V V  V  H  Y      SW  G   DI L++L++ +++
Sbjct: 100 YLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVY------SWKEGACADIALVRLERSIQF 153

Query: 219 SNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYH 278
           S  V PICLP     L  ++ C ++GWG  +     P  +T+Q+ +V I++++ C + Y 
Sbjct: 154 SERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYW 213

Query: 279 NFTKIPTLVQIIKSQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKS 337
                  + +     M+CA     E+  C   +G PL+C ++G W L G++SWG GC + 
Sbjct: 214 RGAGQGPITE----DMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAER 269

Query: 338 EAPPIYLQVSSYQHWIWDCLNGQAL--------ALPAPSR 369
             P +Y+ +S+++ W+   + G  L        AL APS+
Sbjct: 270 NRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQ 309


>gi|5803197 testisin isoform 1 [Homo sapiens]
          Length = 314

 Score =  147 bits (371), Expect = 2e-35
 Identities = 85/272 (31%), Positives = 139/272 (51%), Gaps = 20/272 (7%)

Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQT 177
           +A   RWPW  S+R   +H+C  ++++ +W LT AHC    +    +   S W+ Q  Q 
Sbjct: 47  DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCF---ETYSDLSDPSGWMVQFGQL 103

Query: 178 ASDVPVLQVIM--HSRYRAQRFW---SWVGQAN-DIGLLKLKQELKYSNYVRPICLPGTD 231
            S +P    +   ++RY     +    ++G +  DI L+KL   + Y+ +++PICL  + 
Sbjct: 104 TS-MPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQAST 162

Query: 232 YVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIK 291
           +  ++ + C VTGWG  K D   P   T+QE +V I+NN  C++ +  +    +  + I 
Sbjct: 163 FEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY----SFRKDIF 218

Query: 292 SQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQ 350
             M+CA +    K  C+  +G PL C+  G WY +G+VSWG GC +   P +Y  +S + 
Sbjct: 219 GDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHF 278

Query: 351 HWIWDCLNGQALALPAPSRTLLL-----ALPL 377
            WI   +    ++ P PS  LL      ALPL
Sbjct: 279 EWIQKLMAQSGMSQPDPSWPLLFFPLLWALPL 310


>gi|21614531 testisin isoform 2 [Homo sapiens]
          Length = 312

 Score =  145 bits (367), Expect = 5e-35
 Identities = 85/274 (31%), Positives = 139/274 (50%), Gaps = 26/274 (9%)

Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSP--WIDQMT 175
           +A   RWPW  S+R   +H+C  ++++ +W LT AHC       +   +  P  W+ Q  
Sbjct: 47  DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHC-------FETDLSDPSGWMVQFG 99

Query: 176 QTASDVPVLQVIM--HSRYRAQRFW---SWVGQAN-DIGLLKLKQELKYSNYVRPICLPG 229
           Q  S +P    +   ++RY     +    ++G +  DI L+KL   + Y+ +++PICL  
Sbjct: 100 QLTS-MPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQA 158

Query: 230 TDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQI 289
           + +  ++ + C VTGWG  K D   P   T+QE +V I+NN  C++ +  +    +  + 
Sbjct: 159 STFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY----SFRKD 214

Query: 290 IKSQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSS 348
           I   M+CA +    K  C+  +G PL C+  G WY +G+VSWG GC +   P +Y  +S 
Sbjct: 215 IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISH 274

Query: 349 YQHWIWDCLNGQALALPAPSRTLLL-----ALPL 377
           +  WI   +    ++ P PS  LL      ALPL
Sbjct: 275 HFEWIQKLMAQSGMSQPDPSWPLLFFPLLWALPL 308


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  142 bits (359), Expect = 4e-34
 Identities = 85/243 (34%), Positives = 124/243 (51%), Gaps = 19/243 (7%)

Query: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD-VIYSVRVGSPWIDQMTQTASDV 181
           RWPW VS+R +G H+C G++++  WVLT AHC   R+ V+   RV +  + Q +     +
Sbjct: 173 RWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQL 232

Query: 182 PVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCT 241
            V  V+ H  Y   R  +    +NDI L+ L   L  + Y++P+CLP     L D   CT
Sbjct: 233 GVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICT 292

Query: 242 VTGWGLSKADGMWPQFRTIQEKEVIILNNKECD--NFYHNFTKIPTLVQIIKSQMMCAED 299
           VTGWG ++  G   Q   +QE  V I++N  C+  +FY N          IK +M CA  
Sbjct: 293 VTGWGNTQYYGQ--QAGVLQEARVPIISNDVCNGADFYGN---------QIKPKMFCAGY 341

Query: 300 THRE-KFCYELTGEPLVC----SMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIW 354
                  C   +G P VC    S    W L G+VSWG GC  ++ P +Y +VS ++ WI+
Sbjct: 342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIF 401

Query: 355 DCL 357
             +
Sbjct: 402 QAI 404


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  142 bits (359), Expect = 4e-34
 Identities = 84/242 (34%), Positives = 122/242 (50%), Gaps = 34/242 (14%)

Query: 124 WPWMVSVRANGT---HICAGTIIASQWVLTVAHCL-------IWRDVIYSVRVGSPWIDQ 173
           WPW VS++   T   H+C G++I  QWVLT AHC        +WR  IYS   G   +  
Sbjct: 402 WPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR--IYS---GILNLSD 456

Query: 174 MTQTASDVPVLQVIMHSRYRAQRFWSWVGQAN-DIGLLKLKQELKYSNYVRPICLPGTDY 232
           +T+      + ++I+H  Y+       V + N DI L+KL+  L Y+ + +PICLP    
Sbjct: 457 ITKDTPFSQIKEIIIHQNYK-------VSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509

Query: 233 VLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKS 292
               ++ C VTGWG SK  G       +Q+  + ++ N+EC   Y ++         I  
Sbjct: 510 TSTIYTNCWVTGWGFSKEKGEIQNI--LQKVNIPLVTNEECQKRYQDYK--------ITQ 559

Query: 293 QMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQH 351
           +M+CA      K  C   +G PLVC   G W LVG+ SWG GC + E P +Y +V+ Y  
Sbjct: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619

Query: 352 WI 353
           WI
Sbjct: 620 WI 621


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  142 bits (359), Expect = 4e-34
 Identities = 85/243 (34%), Positives = 124/243 (51%), Gaps = 19/243 (7%)

Query: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD-VIYSVRVGSPWIDQMTQTASDV 181
           RWPW VS+R +G H+C G++++  WVLT AHC   R+ V+   RV +  + Q +     +
Sbjct: 173 RWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQL 232

Query: 182 PVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCT 241
            V  V+ H  Y   R  +    +NDI L+ L   L  + Y++P+CLP     L D   CT
Sbjct: 233 GVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICT 292

Query: 242 VTGWGLSKADGMWPQFRTIQEKEVIILNNKECD--NFYHNFTKIPTLVQIIKSQMMCAED 299
           VTGWG ++  G   Q   +QE  V I++N  C+  +FY N          IK +M CA  
Sbjct: 293 VTGWGNTQYYGQ--QAGVLQEARVPIISNDVCNGADFYGN---------QIKPKMFCAGY 341

Query: 300 THRE-KFCYELTGEPLVC----SMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIW 354
                  C   +G P VC    S    W L G+VSWG GC  ++ P +Y +VS ++ WI+
Sbjct: 342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIF 401

Query: 355 DCL 357
             +
Sbjct: 402 QAI 404


>gi|148806900 epidermis-specific serine protease-like protein [Homo
           sapiens]
          Length = 328

 Score =  141 bits (356), Expect = 9e-34
 Identities = 82/254 (32%), Positives = 124/254 (48%), Gaps = 14/254 (5%)

Query: 104 CGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVI 161
           CG        +   +A A RWPW VS+  +   IC G++++ + +LT AHC+   W    
Sbjct: 19  CGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFS 78

Query: 162 YSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNY 221
           Y+V +GS  +    +      V ++++H +Y+            D+ LLKL  ++ +++ 
Sbjct: 79  YTVWLGSITVGDSRKRVKYY-VSKIVIHPKYQ--------DTTADVALLKLSSQVTFTSA 129

Query: 222 VRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNF- 280
           + PICLP     L     C VTGWG  K          +QE EV I++ + C+  Y+   
Sbjct: 130 ILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIG 189

Query: 281 TKIPTLVQIIKSQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEA 339
             +P L  +IK   +CA DT   K  C   +G PL C ++G W   G+VSWG  C KS  
Sbjct: 190 IFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGKS-L 248

Query: 340 PPIYLQVSSYQHWI 353
           P +Y  V  YQ WI
Sbjct: 249 PGVYTNVIYYQKWI 262


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  140 bits (352), Expect = 3e-33
 Identities = 89/264 (33%), Positives = 130/264 (49%), Gaps = 20/264 (7%)

Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQ- 176
           E+   RWPW  S+R    H C G++++ +WVL+ AHC  ++   Y     S W  Q+ + 
Sbjct: 60  ESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHC--FQKHYYP----SEWTVQLGEL 113

Query: 177 TASDVPVLQVIMHSRYRAQRFW----SWVGQANDIGLLKLKQELKYSNYVRPICLPGTDY 232
           T+   P       SRY+ Q       +     NDI LL+L   + Y+ Y++PIC+  + +
Sbjct: 114 TSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTF 173

Query: 233 VLKDHSRCTVTGWGLSKADGM-WPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIK 291
                  C VTGWGL    G   P    ++E +V ILNN  C+  +      P+   +I 
Sbjct: 174 NFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQ----PSSRSMIW 229

Query: 292 SQMMCA--EDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSY 349
             M CA  ED   +  C   +G PLVC  +G WY VG+VSWG  C +   P +Y  +S Y
Sbjct: 230 DSMFCAGAEDGSVDT-CKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVY 288

Query: 350 QHWIWDCLNGQALALPAPSRTLLL 373
            HWI   ++  +   P PS+ LLL
Sbjct: 289 FHWIRRVMS-HSTPRPNPSQLLLL 311


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  139 bits (351), Expect = 3e-33
 Identities = 85/246 (34%), Positives = 128/246 (52%), Gaps = 24/246 (9%)

Query: 118 EAVARRWPWMVSVRANGT---HICAGTIIASQWVLTVAHCLIWRDV--IYSVRVGSP--- 169
           EA   +WPW VS+R +G    H C G++I  QWVLT AHC +  DV  + ++RV      
Sbjct: 36  EAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQLREQH 94

Query: 170 --WIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICL 227
             + DQ+      +PV ++I+H ++   +  +      DI LL+L++ +  S++V  + L
Sbjct: 95  LYYQDQL------LPVSRIIVHPQFYTAQIGA------DIALLELEEPVNVSSHVHTVTL 142

Query: 228 PGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLV 287
           P           C VTGWG    D   P    +++ +V I+ N  CD  YH        V
Sbjct: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202

Query: 288 QIIKSQMMCAEDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVS 347
           +I++  M+CA +T R+  C   +G PLVC + GTW   G+VSWG GC +   P IY +V+
Sbjct: 203 RIVRDDMLCAGNTRRDS-CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261

Query: 348 SYQHWI 353
            Y  WI
Sbjct: 262 YYLDWI 267


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  136 bits (343), Expect = 3e-32
 Identities = 84/246 (34%), Positives = 126/246 (51%), Gaps = 24/246 (9%)

Query: 118 EAVARRWPWMVSVRANGT---HICAGTIIASQWVLTVAHCLIWRDV--IYSVRVGSP--- 169
           EA   +WPW VS+R       H C G++I  QWVLT AHC +  DV  + ++RV      
Sbjct: 36  EAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQLREQH 94

Query: 170 --WIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICL 227
             + DQ+      +PV ++I+H ++   +  +      DI LL+L++ +  S++V  + L
Sbjct: 95  LYYQDQL------LPVSRIIVHPQFYTAQIGA------DIALLELEEPVNVSSHVHTVTL 142

Query: 228 PGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLV 287
           P           C VTGWG    D   P    +++ +V I+ N  CD  YH        V
Sbjct: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202

Query: 288 QIIKSQMMCAEDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVS 347
           +I++  M+CA +T R+  C   +G PLVC + GTW   G+VSWG GC +   P IY +V+
Sbjct: 203 RIVRDDMLCAGNTRRDS-CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261

Query: 348 SYQHWI 353
            Y  WI
Sbjct: 262 YYLDWI 267


>gi|21614533 testisin isoform 3 [Homo sapiens]
          Length = 300

 Score =  135 bits (339), Expect = 8e-32
 Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 36/273 (13%)

Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQT 177
           +A   RWPW  S+R   +H+C  ++++ +W LT AHC    +    +   S W+ Q  Q 
Sbjct: 47  DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCF---ETYSDLSDPSGWMVQFGQL 103

Query: 178 ASDVPVLQVIM--HSRYRAQRFW---SWVGQAN-DIGLLKLKQELKYSNYVRPICLPGTD 231
            S +P    +   ++RY     +    ++G +  DI L+KL   + Y+ +++PICL  + 
Sbjct: 104 TS-MPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQAST 162

Query: 232 YVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIK 291
           +  ++ + C VTGWG  K D   P   T+QE +V I+NN  C++ +  ++          
Sbjct: 163 FEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYS---------- 212

Query: 292 SQMMCAEDTHREKFCYEL--TGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSY 349
                     R+    ++  +G PL C+  G WY +G+VSWG GC +   P +Y  +S +
Sbjct: 213 ---------FRKDIFGDMGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHH 263

Query: 350 QHWIWDCLNGQALALPAPSRTLLL-----ALPL 377
             WI   +    ++ P PS  LL      ALPL
Sbjct: 264 FEWIQKLMAQSGMSQPDPSWPLLFFPLLWALPL 296


>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
          Length = 410

 Score =  132 bits (331), Expect = 7e-31
 Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 24/249 (9%)

Query: 122 RRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLI----WRDVIYSVRVGSPWIDQMTQT 177
           ++WPW VS++ +  H C G++I  +WVLT AHC+     W    + +     W DQ  + 
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRW-DQAWKH 230

Query: 178 ASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDH 237
             D+     I  S +       +    +DI L  L   + YS++++P CLP   + ++  
Sbjct: 231 LEDI-----IFPSNF------DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAG 279

Query: 238 SRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA 297
           + C VTGWG        P    +QE E+ I+ +++C     N  K  +  +++    +C 
Sbjct: 280 TECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKN--KNISKSKMVTRGTVCG 337

Query: 298 EDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWD-- 355
            +   +  C   +G PLVC + GTW  VG+VSWG GC +   P +Y +VS Y+ WI D  
Sbjct: 338 YNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397

Query: 356 ----CLNGQ 360
               CLN +
Sbjct: 398 RQASCLNSK 406


>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
           sapiens]
          Length = 410

 Score =  132 bits (331), Expect = 7e-31
 Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 24/249 (9%)

Query: 122 RRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLI----WRDVIYSVRVGSPWIDQMTQT 177
           ++WPW VS++ +  H C G++I  +WVLT AHC+     W    + +     W DQ  + 
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRW-DQAWKH 230

Query: 178 ASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDH 237
             D+     I  S +       +    +DI L  L   + YS++++P CLP   + ++  
Sbjct: 231 LEDI-----IFPSNF------DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAG 279

Query: 238 SRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA 297
           + C VTGWG        P    +QE E+ I+ +++C     N  K  +  +++    +C 
Sbjct: 280 TECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKN--KNISKSKMVTRGTVCG 337

Query: 298 EDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWD-- 355
            +   +  C   +G PLVC + GTW  VG+VSWG GC +   P +Y +VS Y+ WI D  
Sbjct: 338 YNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397

Query: 356 ----CLNGQ 360
               CLN +
Sbjct: 398 RQASCLNSK 406


>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
           sapiens]
          Length = 410

 Score =  132 bits (331), Expect = 7e-31
 Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 24/249 (9%)

Query: 122 RRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLI----WRDVIYSVRVGSPWIDQMTQT 177
           ++WPW VS++ +  H C G++I  +WVLT AHC+     W    + +     W DQ  + 
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRW-DQAWKH 230

Query: 178 ASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDH 237
             D+     I  S +       +    +DI L  L   + YS++++P CLP   + ++  
Sbjct: 231 LEDI-----IFPSNF------DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAG 279

Query: 238 SRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA 297
           + C VTGWG        P    +QE E+ I+ +++C     N  K  +  +++    +C 
Sbjct: 280 TECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKN--KNISKSKMVTRGTVCG 337

Query: 298 EDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWD-- 355
            +   +  C   +G PLVC + GTW  VG+VSWG GC +   P +Y +VS Y+ WI D  
Sbjct: 338 YNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397

Query: 356 ----CLNGQ 360
               CLN +
Sbjct: 398 RQASCLNSK 406


>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
          Length = 321

 Score =  130 bits (327), Expect = 2e-30
 Identities = 75/237 (31%), Positives = 116/237 (48%), Gaps = 17/237 (7%)

Query: 119 AVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIW--RDVIYSVRVGSPWIDQMTQ 176
           A A  WPW  S+R    H+C G++++ QWVLT AHC         Y V +G     ++T 
Sbjct: 44  APAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGEL---EITL 100

Query: 177 TASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKD 236
           +     V Q+I+HS    Q      G + DI L++L   +  S+ + P+CLP        
Sbjct: 101 SPHFSTVRQIILHSSPSGQP-----GTSGDIALVELSVPVTLSSRILPVCLPEASDDFCP 155

Query: 237 HSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMC 296
             RC VTGWG ++     P   +++E +V +++ + C   Y           I++  M+C
Sbjct: 156 GIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGG-----SILQPDMLC 210

Query: 297 AEDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
           A        C + +G PLVC + G W   G+VSWG GC +   P +Y +V +Y +WI
Sbjct: 211 ARGPGDA--CQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWI 265


>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score =  129 bits (324), Expect = 4e-30
 Identities = 74/238 (31%), Positives = 118/238 (49%), Gaps = 31/238 (13%)

Query: 124 WPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD------VIYSVRVGSPWIDQMTQT 177
           WPW  S++  G H C  ++I+S+W+L+ AHC   ++      V + + V  P++ +  Q 
Sbjct: 196 WPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTRKVQN 255

Query: 178 ASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDH 237
                   +I H  Y +       G  +DI L++L +E+ ++ Y+R ICLP     L ++
Sbjct: 256 --------IIFHENYSSP------GLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSEN 301

Query: 238 SRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA 297
               VTGWG    +G +P    +QE  + I++NK C+  Y            +   M+CA
Sbjct: 302 DNVVVTGWGTLYMNGSFPVI--LQEDFLKIIDNKICNASY-------AYSGFVTDTMLCA 352

Query: 298 EDTHREK-FCYELTGEPLVC-SMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
                E   C   +G PL        W+LVG+VSWG GC K   P +Y +V+SY++WI
Sbjct: 353 GFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  128 bits (322), Expect = 8e-30
 Identities = 75/246 (30%), Positives = 127/246 (51%), Gaps = 28/246 (11%)

Query: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHC-LIWRDVI---YSVRVGSPWIDQMTQTA 178
           +WPW VS+    THIC GT+I +QWVLT AHC  + R+ +   + V  G+  + Q+ + A
Sbjct: 336 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA 395

Query: 179 SDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHS 238
           S   + ++I++S Y  +          DI L++L + L  S ++ P CLP        + 
Sbjct: 396 S---IAEIIINSNYTDEE------DDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNE 446

Query: 239 RCTVTGWGLSK-ADGMWPQFRTIQEKEVIILNNKECDNF--YHNFTKIPTLVQIIKSQMM 295
            C +TG+G ++  D     F  ++E +V +++ K+C+++  Y ++         +  +MM
Sbjct: 447 TCWITGFGKTRETDDKTSPF--LREVQVNLIDFKKCNDYLVYDSY---------LTPRMM 495

Query: 296 CAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIW 354
           CA D    +  C   +G PLVC     WYL G+ SWG GC +   P +Y +V+    WI+
Sbjct: 496 CAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIY 555

Query: 355 DCLNGQ 360
             +  +
Sbjct: 556 SKMESE 561


>gi|34098976 marapsin 2 [Homo sapiens]
          Length = 326

 Score =  128 bits (322), Expect = 8e-30
 Identities = 94/288 (32%), Positives = 132/288 (45%), Gaps = 23/288 (7%)

Query: 103 SCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD--- 159
           +CG    +   L    A  R+WPW VSV   G H+C G+I+   WVL+ AHC   RD   
Sbjct: 50  ACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHC-FHRDKNI 108

Query: 160 VIYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYS 219
            IY + VG   +           V +VI+H  Y     +  +G   D+ L++LK  + +S
Sbjct: 109 KIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTY---EMYHPIG--GDVALVQLKTRIVFS 163

Query: 220 NYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHN 279
             V P+CL  T  V    + C  TGWGL    G       +QE ++ ++    C   Y +
Sbjct: 164 ESVLPVCL-ATPEVNLTSANCWATGWGLVSKQGETSD--ELQEMQLPLILEPWCHLLYGH 220

Query: 280 FTKIPTLVQIIKSQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSE 338
                  +  I   M+CA D    K  C   +G PLVC    +W  +G+VSWG GC    
Sbjct: 221 -------MSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPL 273

Query: 339 APPIYLQVSSYQHWIWDCLNGQALALPA-PSRTLLLALPLPLSLLAAL 385
            P +Y  VS +  WI  C N +    PA P+  L  AL   LS+L A+
Sbjct: 274 YPGVYASVSYFSKWI--CDNIEITPTPAQPAPALSPALGPTLSVLMAM 319


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  127 bits (320), Expect = 1e-29
 Identities = 78/241 (32%), Positives = 116/241 (48%), Gaps = 22/241 (9%)

Query: 119 AVARRWPWMVSVRANGT---HICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQ-- 173
           +V   WPW V++        H+C G+II +QW+LT AHC    +    +RV S  ++Q  
Sbjct: 394 SVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSE 453

Query: 174 MTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYV 233
           + +  S   V ++I+H +Y+            DI LLKL+  + Y++  RPICLP     
Sbjct: 454 IKEDTSFFGVQEIIIHDQYKMAE------SGYDIALLKLETTVNYTDSQRPICLPSKGDR 507

Query: 234 LKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQ 293
              ++ C VTGWG  K         T+Q+ ++ ++ N+EC   Y            I  +
Sbjct: 508 NVIYTDCWVTGWGYRKLRDKIQN--TLQKAKIPLVTNEECQKRYRGHK--------ITHK 557

Query: 294 MMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHW 352
           M+CA      K  C   +G PL C     W+LVG+ SWG GC + E P +Y  V  Y  W
Sbjct: 558 MICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDW 617

Query: 353 I 353
           I
Sbjct: 618 I 618


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  125 bits (314), Expect = 6e-29
 Identities = 85/267 (31%), Positives = 130/267 (48%), Gaps = 19/267 (7%)

Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD--VIYSVRVGSPWIDQMT 175
           EA    WPW V +R  G + C G II   W+LT AHC+  ++  + +++  G    +   
Sbjct: 580 EACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKE 639

Query: 176 QTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLK 235
            T        +I+H  +    + S      DI L++L   L+Y++ VRP+CLP +   L 
Sbjct: 640 STEQVRRAKHIIVHEDFNTLSYDS------DIALIQLSSPLEYNSVVRPVCLPHSAEPLF 693

Query: 236 DHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMM 295
               C VTGWG   ADG       +Q+ +V +L  + C++ Y++          I  +M+
Sbjct: 694 SSEICAVTGWGSISADGGLAS--RLQQIQVHVLEREVCEHTYYS-----AHPGGITEKMI 746

Query: 296 CA--EDTHREKFCYELTGEPLVCSME-GTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHW 352
           CA    +  + FC   +G PLVC  E G + L G+VSWGAGC +   P ++ +V  +  W
Sbjct: 747 CAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDW 806

Query: 353 IWDCLNGQA-LALPAPSRTLLLALPLP 378
           I   +NG A L      +TL   LP P
Sbjct: 807 IQSKINGPASLQTNNKCKTLKQQLPPP 833



 Score =  104 bits (260), Expect = 1e-22
 Identities = 69/223 (30%), Positives = 110/223 (49%), Gaps = 20/223 (8%)

Query: 125 PWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVIYSVRV--GSPWIDQMTQTASD 180
           PW VS++++  H C G++I    V+T AHCL  +    + ++ V  G   + Q  +   +
Sbjct: 59  PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118

Query: 181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC 240
           +PV ++I H  Y ++ + S      DI LL LK ++K+ N V+PICLP +D  ++    C
Sbjct: 119 IPVSKIITHPEYNSREYMS-----PDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILC 173

Query: 241 TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA--E 298
             +GWG  K          +QE E+ I++++ C+    +    P     +   M+CA   
Sbjct: 174 LSSGWG--KISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPP-----LGRTMLCAGFP 226

Query: 299 DTHREKFCYELTGEPLVCSM-EGTWYLVGLVSWGAGCQKSEAP 340
           D   +  C   +G PLVC    G W L G+ SW AGC     P
Sbjct: 227 DWGMDA-CQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVP 268


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  125 bits (313), Expect = 8e-29
 Identities = 70/234 (29%), Positives = 118/234 (50%), Gaps = 19/234 (8%)

Query: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVIYSVRVGSPWIDQMTQTASD 180
           +WPW  S++  G H+C G++I   W++T AHC+  ++    ++++VG   +  +   A  
Sbjct: 227 QWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVG--LVSLLDNPAPS 284

Query: 181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC 240
             V +++ HS+Y+ +R        NDI L+KL   L ++  ++P+CLP ++    D   C
Sbjct: 285 HLVEKIVYHSKYKPKRL------GNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVC 338

Query: 241 TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAED- 299
             +GWG ++ DG       +    V +++NK C++             II   M+CA   
Sbjct: 339 WTSGWGATE-DGAGDASPVLNHAAVPLISNKICNH-------RDVYGGIISPSMLCAGYL 390

Query: 300 THREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
           T     C   +G PLVC     W LVG  S+G GC +   P +Y +V+S+  WI
Sbjct: 391 TGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 444


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  122 bits (307), Expect = 4e-28
 Identities = 72/265 (27%), Positives = 122/265 (46%), Gaps = 35/265 (13%)

Query: 103 SCGF---SYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD 159
           +CG    S  Q   +    A+   WPW VS+     H+C G+II  +W++T AHC+    
Sbjct: 280 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCV---- 335

Query: 160 VIYSVRVGSPW---------IDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLL 210
                 + +PW                 +   V +VI H  Y ++       + NDI L+
Sbjct: 336 ---EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKT------KNNDIALM 386

Query: 211 KLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNN 270
           KL++ L +++ V+P+CLP    +L+    C ++GWG ++  G   +   +   +V+++  
Sbjct: 387 KLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIET 444

Query: 271 KECDNFYHNFTKIPTLVQIIKSQMMCAEDTH-REKFCYELTGEPLVCSMEGTWYLVGLVS 329
           + C++ Y           +I   M+CA         C   +G PLV S    W+L+G  S
Sbjct: 445 QRCNSRY-------VYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTS 497

Query: 330 WGAGCQKSEAPPIYLQVSSYQHWIW 354
           WG+GC K+  P +Y  V  +  WI+
Sbjct: 498 WGSGCAKAYRPGVYGNVMVFTDWIY 522


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  122 bits (307), Expect = 4e-28
 Identities = 72/265 (27%), Positives = 122/265 (46%), Gaps = 35/265 (13%)

Query: 103 SCGF---SYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD 159
           +CG    S  Q   +    A+   WPW VS+     H+C G+II  +W++T AHC+    
Sbjct: 243 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCV---- 298

Query: 160 VIYSVRVGSPW---------IDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLL 210
                 + +PW                 +   V +VI H  Y ++       + NDI L+
Sbjct: 299 ---EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKT------KNNDIALM 349

Query: 211 KLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNN 270
           KL++ L +++ V+P+CLP    +L+    C ++GWG ++  G   +   +   +V+++  
Sbjct: 350 KLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIET 407

Query: 271 KECDNFYHNFTKIPTLVQIIKSQMMCAEDTH-REKFCYELTGEPLVCSMEGTWYLVGLVS 329
           + C++ Y           +I   M+CA         C   +G PLV S    W+L+G  S
Sbjct: 408 QRCNSRY-------VYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTS 460

Query: 330 WGAGCQKSEAPPIYLQVSSYQHWIW 354
           WG+GC K+  P +Y  V  +  WI+
Sbjct: 461 WGSGCAKAYRPGVYGNVMVFTDWIY 485


>gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo
           sapiens]
          Length = 282

 Score =  122 bits (306), Expect = 5e-28
 Identities = 86/281 (30%), Positives = 132/281 (46%), Gaps = 54/281 (19%)

Query: 79  TQTLPSTTMETQFPVSEGKVDPY-RSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHI 137
           T  L S  ++ Q P  EG   P+ R+CG +      ++       +WPW VS+   GT+I
Sbjct: 12  TSPLSSARLDYQ-PSIEG---PWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYI 67

Query: 138 CAGTIIASQWVLTVAHCL-IWRDV-IYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQ 195
           C+G++I  QWVLT AHCL  ++D+ +YSV VG   + Q  + ++ +P+ ++++H  +   
Sbjct: 68  CSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL 124

Query: 196 RFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWP 255
                   + DI LLKL+  + +S +V+P+CLP   +     S C V GWG +   G   
Sbjct: 125 -------MSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKG--- 174

Query: 256 QFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCYELT---GE 312
                       LN+ +                   S   C E   RE F + LT   G 
Sbjct: 175 -----------FLNHPD-------------------SVKSCCEFI-RECFQFTLTVDSGS 203

Query: 313 PLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
            LVC M+ TW  +G+VSW   C +   P IY   + +  WI
Sbjct: 204 SLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244


>gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo
           sapiens]
          Length = 282

 Score =  122 bits (306), Expect = 5e-28
 Identities = 86/281 (30%), Positives = 132/281 (46%), Gaps = 54/281 (19%)

Query: 79  TQTLPSTTMETQFPVSEGKVDPY-RSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHI 137
           T  L S  ++ Q P  EG   P+ R+CG +      ++       +WPW VS+   GT+I
Sbjct: 12  TSPLSSARLDYQ-PSIEG---PWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYI 67

Query: 138 CAGTIIASQWVLTVAHCL-IWRDV-IYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQ 195
           C+G++I  QWVLT AHCL  ++D+ +YSV VG   + Q  + ++ +P+ ++++H  +   
Sbjct: 68  CSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL 124

Query: 196 RFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWP 255
                   + DI LLKL+  + +S +V+P+CLP   +     S C V GWG +   G   
Sbjct: 125 -------MSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKG--- 174

Query: 256 QFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCYELT---GE 312
                       LN+ +                   S   C E   RE F + LT   G 
Sbjct: 175 -----------FLNHPD-------------------SVKSCCEFI-RECFQFTLTVDSGS 203

Query: 313 PLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
            LVC M+ TW  +G+VSW   C +   P IY   + +  WI
Sbjct: 204 SLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  122 bits (306), Expect = 5e-28
 Identities = 72/265 (27%), Positives = 119/265 (44%), Gaps = 23/265 (8%)

Query: 95  EGKVDPYRSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHC 154
           +G  + +  CG        +    +    WPW  S++  G HIC G +IA +WV+T AHC
Sbjct: 559 DGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHC 618

Query: 155 L----IWRDVIYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLL 210
                +   V+++V +G  W +          V ++++H  +             D+ LL
Sbjct: 619 FQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEED------SHDYDVALL 672

Query: 211 KLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNN 270
           +L   +  S  VRP+CLP   +  +    C +TGWG  +  G  P    +Q+ +V ++  
Sbjct: 673 QLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG--PISNALQKVDVQLIPQ 730

Query: 271 KECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREK-FCYELTGEPLVC-SMEGTWYLVGLV 328
             C   Y            +  +M+CA     +K  C   +G PLVC ++ G W+L GLV
Sbjct: 731 DLCSEVYR---------YQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLV 781

Query: 329 SWGAGCQKSEAPPIYLQVSSYQHWI 353
           SWG GC +     +Y +++    WI
Sbjct: 782 SWGLGCGRPNYFGVYTRITGVISWI 806


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,222,375
Number of Sequences: 37866
Number of extensions: 764361
Number of successful extensions: 2699
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2217
Number of HSP's gapped (non-prelim): 200
length of query: 385
length of database: 18,247,518
effective HSP length: 104
effective length of query: 281
effective length of database: 14,309,454
effective search space: 4020956574
effective search space used: 4020956574
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.