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Search of human proteins with 7019465
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo
sapiens]
(376 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo sapiens] 764 0.0
gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo sapi... 688 0.0
gi|148839372 thioredoxin domain containing 3 [Homo sapiens] 144 2e-34
gi|4505413 non-metastatic cells 5, protein expressed in (nucleos... 122 7e-28
gi|5031951 nucleoside diphosphate kinase type 6 [Homo sapiens] 93 4e-19
gi|66392203 NME1-NME2 protein [Homo sapiens] 89 8e-18
gi|30023828 thioredoxin domain containing 6 [Homo sapiens] 81 1e-15
gi|4826862 nucleoside diphosphate kinase 4 [Homo sapiens] 75 7e-14
gi|37693993 nucleoside diphosphate kinase 3 [Homo sapiens] 74 3e-13
gi|38045913 non-metastatic cells 1, protein (NM23A) expressed in... 71 1e-12
gi|4557797 non-metastatic cells 1, protein (NM23A) expressed in ... 71 1e-12
gi|66392227 nucleoside diphosphate kinase B [Homo sapiens] 70 2e-12
gi|66392205 nucleoside diphosphate kinase B [Homo sapiens] 70 2e-12
gi|66392192 nucleoside diphosphate kinase B [Homo sapiens] 70 2e-12
gi|4505409 nucleoside diphosphate kinase B [Homo sapiens] 70 2e-12
gi|47078261 double C2-like domains, alpha [Homo sapiens] 31 1.6
gi|112363080 microtubule associated serine/threonine kinase 2 [H... 30 3.5
gi|191251777 breast carcinoma amplified sequence 1 [Homo sapiens] 29 6.0
>gi|7019465 nucleoside diphosphate kinase 7 isoform a [Homo sapiens]
Length = 376
Score = 764 bits (1972), Expect = 0.0
Identities = 376/376 (100%), Positives = 376/376 (100%)
Query: 1 MNHSERFVFIAEWYDPNASLLRRYELLFYPGDGSVEMHDVKNHRTFLKRTKYDNLHLEDL 60
MNHSERFVFIAEWYDPNASLLRRYELLFYPGDGSVEMHDVKNHRTFLKRTKYDNLHLEDL
Sbjct: 1 MNHSERFVFIAEWYDPNASLLRRYELLFYPGDGSVEMHDVKNHRTFLKRTKYDNLHLEDL 60
Query: 61 FIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGFTI 120
FIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGFTI
Sbjct: 61 FIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGFTI 120
Query: 121 TKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPAN 180
TKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPAN
Sbjct: 121 TKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPAN 180
Query: 181 SGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCT 240
SGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCT
Sbjct: 181 SGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCT 240
Query: 241 CCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVT 300
CCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVT
Sbjct: 241 CCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVT 300
Query: 301 EMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLP 360
EMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLP
Sbjct: 301 EMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLP 360
Query: 361 EDGLLEVQYFFKILDN 376
EDGLLEVQYFFKILDN
Sbjct: 361 EDGLLEVQYFFKILDN 376
>gi|37574614 nucleoside diphosphate kinase 7 isoform b [Homo
sapiens]
Length = 340
Score = 688 bits (1776), Expect = 0.0
Identities = 340/340 (100%), Positives = 340/340 (100%)
Query: 37 MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA 96
MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA
Sbjct: 1 MHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLA 60
Query: 97 LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG 156
LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG
Sbjct: 61 LIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTG 120
Query: 157 PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR 216
PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR
Sbjct: 121 PIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAR 180
Query: 217 EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM 276
EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM
Sbjct: 181 EMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNM 240
Query: 277 DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL 336
DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL
Sbjct: 241 DRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHL 300
Query: 337 RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN 376
RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN
Sbjct: 301 RPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN 340
>gi|148839372 thioredoxin domain containing 3 [Homo sapiens]
Length = 588
Score = 144 bits (362), Expect = 2e-34
Identities = 88/266 (33%), Positives = 147/266 (55%), Gaps = 17/266 (6%)
Query: 92 EKTLALIKPDAI-SKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELI 150
EKTLAL++P+ + +++ II F I + + ++LS KEA ++++ +FN+LI
Sbjct: 316 EKTLALLRPNLFHERKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYENEDYFNKLI 375
Query: 151 QFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIR-NAAHGPD 209
+ +T+GP +A+ +LRD+ + WK+LLGP A ES+ A F D + N +G D
Sbjct: 376 ENMTSGPSLALVLLRDNGLQYWKQLLGPRTVEEAIEYFPESLCAQFAMDSLPVNQLYGSD 435
Query: 210 SFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEIS 269
S +A RE++ FFP G ++KPHA SE +IL +++AGF+++
Sbjct: 436 SLETAEREIQHFFPLQSTLG-------------LIKPHATSE-QREQILKIVKEAGFDLT 481
Query: 270 AMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPAD 329
++ + +E+ Y G Y D++ + GP + M + + NA +R GP D
Sbjct: 482 QVKKMFLTPEQIEKIYPKVTG-KDFYKDLLEMLSVGPSMVMILTKWNAVAEWRRLMGPTD 540
Query: 330 PEIARHLRPGTLRAIFGKTKIQNAVH 355
PE A+ L P ++RA FG +K++N VH
Sbjct: 541 PEEAKLLSPDSIRAQFGISKLKNIVH 566
Score = 84.0 bits (206), Expect = 2e-16
Identities = 42/132 (31%), Positives = 77/132 (58%), Gaps = 1/132 (0%)
Query: 92 EKTLALIKPDAISKAGE-IIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELI 150
+ TL LIKP A S+ E I++I+ +AGF +T++K M L+ ++ + + F+ +L+
Sbjct: 451 QSTLGLIKPHATSEQREQILKIVKEAGFDLTQVKKMFLTPEQIEKIYPKVTGKDFYKDLL 510
Query: 151 QFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDS 210
+ ++ GP + M + + +A+ EW+RL+GP + A+ + +SIRA FG ++N HG +
Sbjct: 511 EMLSVGPSMVMILTKWNAVAEWRRLMGPTDPEEAKLLSPDSIRAQFGISKLKNIVHGASN 570
Query: 211 FASAAREMELFF 222
A + F
Sbjct: 571 AYEAKEVVNRLF 582
Score = 59.3 bits (142), Expect = 5e-09
Identities = 63/307 (20%), Positives = 125/307 (40%), Gaps = 39/307 (12%)
Query: 94 TLALIKPDAI--SKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQ 151
++A+IKPDA+ K EI I KAGF I +L+ ++ ++F+ + F E +
Sbjct: 156 SIAIIKPDAVISKKVLEIKRKITKAGFIIEAEHKTVLTEEQVVNFYSRIADQCDFEEFVS 215
Query: 152 FITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDA----------------------- 188
F+T+G + + + + P+ +TD
Sbjct: 216 FMTSGLSYIL------VVSQGSKHNPPSEETEPQTDTEPNERSEDQPEVEAQVTPGMMKN 269
Query: 189 -SESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPH 247
+S++ + + A+ A+ M+ FFP K T +++P+
Sbjct: 270 KQDSLQEYLERQHLAQLCDIEEDAANVAKFMDAFFPDFKKMKSMKLEK----TLALLRPN 325
Query: 248 AVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPC 307
E +L I+D F+I + + + + Y+ ++ ++ M SGP
Sbjct: 326 LFHE-RKDDVLRIIKDEDFKILEQRQVVLSEKEAQALCKEYEN-EDYFNKLIENMTSGPS 383
Query: 308 VAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQ-NAVHCTDLPEDGLLE 366
+A+ + ++N + +++ GP E A P +L A F + N ++ +D E E
Sbjct: 384 LALVLLRDNGLQYWKQLLGPRTVEEAIEYFPESLCAQFAMDSLPVNQLYGSDSLETAERE 443
Query: 367 VQYFFKI 373
+Q+FF +
Sbjct: 444 IQHFFPL 450
>gi|4505413 non-metastatic cells 5, protein expressed in
(nucleoside-diphosphate kinase) [Homo sapiens]
Length = 212
Score = 122 bits (305), Expect = 7e-28
Identities = 59/132 (44%), Positives = 89/132 (67%)
Query: 92 EKTLALIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQ 151
EKTLA+IKPD + K EI +II ++GFTI + + + LS ++ +F+V+ + FF L
Sbjct: 13 EKTLAIIKPDIVDKEEEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMFFPNLTA 72
Query: 152 FITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSF 211
++++GP++AM + R AI W LLGP NS VA+ +S+RA++GTD +RNA HG + F
Sbjct: 73 YMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSNDF 132
Query: 212 ASAAREMELFFP 223
A+A RE+ FP
Sbjct: 133 AAAEREIRFMFP 144
Score = 50.8 bits (120), Expect = 2e-06
Identities = 36/132 (27%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Query: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 299
T I+KP V + +I I +GF I + + FY G + + ++
Sbjct: 15 TLAIIKPDIVDKE--EEIQDIILRSGFTIVQRRKLRLSPEQCSNFYVEKYGKMF-FPNLT 71
Query: 300 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 359
M SGP VAM + ++ A + E GP + +A+ P +LRAI+G ++NA+H ++
Sbjct: 72 AYMSSGPLVAMILARHKAISYWLELLGPNNSLVAKETHPDSLRAIYGTDDLRNALHGSND 131
Query: 360 PEDGLLEVQYFF 371
E+++ F
Sbjct: 132 FAAAEREIRFMF 143
>gi|5031951 nucleoside diphosphate kinase type 6 [Homo sapiens]
Length = 194
Score = 92.8 bits (229), Expect = 4e-19
Identities = 51/134 (38%), Positives = 79/134 (58%), Gaps = 5/134 (3%)
Query: 94 TLALIKPDAISKAGEIIEIINKA----GFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149
TLALIKPDA++ I+E +++ F I +++ ++ +++ F+ +H+ R F+ L
Sbjct: 22 TLALIKPDAVAHP-LILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFFYQRL 80
Query: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209
++F+ +GPI A + DAI W+ L+GP AR A +SIR FG RN HG D
Sbjct: 81 VEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSD 140
Query: 210 SFASAAREMELFFP 223
S SA+RE+ FFP
Sbjct: 141 SVVSASREIAAFFP 154
Score = 53.1 bits (126), Expect = 4e-07
Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 2/133 (1%)
Query: 240 TCCIVKPHAVSEGL-LGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDM 298
T ++KP AV+ L L + I F I M+ + + + FY ++G Y +
Sbjct: 22 TLALIKPDAVAHPLILEAVHQQILSNKFLIVRMRELLWRKEDCQRFYREHEGRFF-YQRL 80
Query: 299 VTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTD 358
V M SGP A + +A + +R GP ARH+ P ++R FG T +N H +D
Sbjct: 81 VEFMASGPIRAYILAHKDAIQLWRTLMGPTRVFRARHVAPDSIRGSFGLTDTRNTTHGSD 140
Query: 359 LPEDGLLEVQYFF 371
E+ FF
Sbjct: 141 SVVSASREIAAFF 153
>gi|66392203 NME1-NME2 protein [Homo sapiens]
Length = 267
Score = 88.6 bits (218), Expect = 8e-18
Identities = 74/283 (26%), Positives = 123/283 (43%), Gaps = 39/283 (13%)
Query: 92 EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149
E+T IKPD + + GEII+ + GF + LK M S + +VD + RPFF L
Sbjct: 5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGL 64
Query: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209
++++ +GP++AM + + + +LG N ++ +IR F R A+
Sbjct: 65 VKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRTMANLER 121
Query: 210 SFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEIS 269
+F + +KP V GL+G+I+ GF +
Sbjct: 122 TFIA------------------------------IKPDGVQRGLVGEIIKRFEQKGFRLV 151
Query: 270 AMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPAD 329
AM+ ++++ Y K + +V M SGP VAM + N KT R G +
Sbjct: 152 AMKFLRASEEHLKQHYIDLKD-RPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGETN 210
Query: 330 PEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFK 372
P + +PGT+R F +N +H +D + E+ +FK
Sbjct: 211 PADS---KPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFK 250
Score = 48.5 bits (114), Expect = 1e-05
Identities = 34/110 (30%), Positives = 51/110 (46%), Gaps = 6/110 (5%)
Query: 238 NC--TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEY 295
NC T +KP V GL+G+I+ GF + ++ ++E Y K +
Sbjct: 3 NCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKD-RPFF 61
Query: 296 HDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIF 345
+V M+SGP VAM + N KT R G +P + +PGT+R F
Sbjct: 62 AGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDF 108
>gi|30023828 thioredoxin domain containing 6 [Homo sapiens]
Length = 263
Score = 81.3 bits (199), Expect = 1e-15
Identities = 49/144 (34%), Positives = 76/144 (52%), Gaps = 6/144 (4%)
Query: 87 LGSRKEKTLALIKPDAIS--KAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRP 144
+ S + TLA+IKPDA++ K EII I +AGF I + ++ E F+
Sbjct: 93 VSSERTCTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQHKAGEE 152
Query: 145 FFNELIQFITTGPIIAMEILR----DDAICEWKRLLGPANSGVARTDASESIRALFGTDG 200
F +L+ + +GP + + R +D + W+ ++GP + VAR + ES+RA +GT+
Sbjct: 153 AFEKLVHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEM 212
Query: 201 IRNAAHGPDSFASAAREMELFFPS 224
NA HG A RE+ L FPS
Sbjct: 213 PFNAVHGSRDREDADRELALLFPS 236
Score = 73.9 bits (180), Expect = 2e-13
Identities = 48/140 (34%), Positives = 70/140 (50%), Gaps = 5/140 (3%)
Query: 239 CTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDM 298
CT I+KP AV+ G +I+M I++AGFEI + M V FY+ +K + +
Sbjct: 99 CTLAIIKPDAVAHGKTDEIIMKIQEAGFEILTNEERTMTEAEVRLFYQ-HKAGEEAFEKL 157
Query: 299 VTEMYSGPCVAMEIQQ----NNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAV 354
V M SGP + + + + T+R GP DP +AR +P +LRA +G NAV
Sbjct: 158 VHHMCSGPSHLLILTRTEGFEDVVTTWRTVMGPRDPNVARREQPESLRAQYGTEMPFNAV 217
Query: 355 HCTDLPEDGLLEVQYFFKIL 374
H + ED E+ F L
Sbjct: 218 HGSRDREDADRELALLFPSL 237
>gi|4826862 nucleoside diphosphate kinase 4 [Homo sapiens]
Length = 187
Score = 75.5 bits (184), Expect = 7e-14
Identities = 41/141 (29%), Positives = 77/141 (54%), Gaps = 13/141 (9%)
Query: 91 KEKTLALIKPDAISK--AGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNE 148
+E+TL +KPD + + G++I+ + GFT+ +KM+ + + D + +PF+
Sbjct: 37 RERTLVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPA 96
Query: 149 LIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASE----SIRALFGTDGIRNA 204
LI+++++GP++AM + E ++ + + + TD++E +IR F RN
Sbjct: 97 LIRYMSSGPVVAM-------VWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNV 149
Query: 205 AHGPDSFASAAREMELFFPSS 225
H DS A RE++L+F SS
Sbjct: 150 IHASDSVEGAQREIQLWFQSS 170
Score = 54.7 bits (130), Expect = 1e-07
Identities = 42/147 (28%), Positives = 63/147 (42%), Gaps = 7/147 (4%)
Query: 226 GGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFY 285
G GP+ T + T VKP V L+G ++ GF + M+M + E Y
Sbjct: 29 GSGGPSWTRERT---LVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHY 85
Query: 286 EVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIF 345
+ + Y ++ M SGP VAM + N + R G D A PGT+R F
Sbjct: 86 QDLRRKPF-YPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAA---PGTIRGDF 141
Query: 346 GKTKIQNAVHCTDLPEDGLLEVQYFFK 372
+N +H +D E E+Q +F+
Sbjct: 142 SVHISRNVIHASDSVEGAQREIQLWFQ 168
>gi|37693993 nucleoside diphosphate kinase 3 [Homo sapiens]
Length = 169
Score = 73.6 bits (179), Expect = 3e-13
Identities = 45/152 (29%), Positives = 79/152 (51%), Gaps = 6/152 (3%)
Query: 73 LVLIDYGDQYTARQLGSRKEKTLALIKPDAISK--AGEIIEIINKAGFTITKLKMMMLSR 130
LVL + + + A G+ E+T +KPD + + GEI+ + GF + LK++ S
Sbjct: 4 LVLTIFANLFPAACTGAH-ERTFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASE 62
Query: 131 KEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASE 190
+ + + + + RPF+ L++++ +GP++AM D + + L+G N A
Sbjct: 63 ELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGATNPADA---PPG 119
Query: 191 SIRALFGTDGIRNAAHGPDSFASAAREMELFF 222
+IR F + +N HG DS SA RE+ L+F
Sbjct: 120 TIRGDFCIEVGKNLIHGSDSVESARREIALWF 151
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/133 (29%), Positives = 60/133 (45%), Gaps = 4/133 (3%)
Query: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 299
T VKP V L+G+I+ GF++ A+++ + E Y + Y +V
Sbjct: 24 TFLAVKPDGVQRRLVGEIVRRFERKGFKLVALKLVQASEELLREHYAELR-ERPFYGRLV 82
Query: 300 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 359
M SGP VAM Q + +T R G +P A PGT+R F +N +H +D
Sbjct: 83 KYMASGPVVAMVWQGLDVVRTSRALIGATNPADA---PPGTIRGDFCIEVGKNLIHGSDS 139
Query: 360 PEDGLLEVQYFFK 372
E E+ +F+
Sbjct: 140 VESARREIALWFR 152
>gi|38045913 non-metastatic cells 1, protein (NM23A) expressed in
isoform a [Homo sapiens]
Length = 177
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/150 (31%), Positives = 75/150 (50%), Gaps = 11/150 (7%)
Query: 92 EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149
E+T IKPD + + GEII+ + GF + LK M S + +VD + RPFF L
Sbjct: 30 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGL 89
Query: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209
++++ +GP++AM + + + +LG N ++ +IR F RN HG D
Sbjct: 90 VKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 146
Query: 210 SFASAAREMELFFPSSGGCGPANTAKFTNC 239
S SA +E+ L+F P +T+C
Sbjct: 147 SVESAEKEIGLWF------HPEELVDYTSC 170
Score = 56.6 bits (135), Expect = 4e-08
Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 6/142 (4%)
Query: 232 NTAKFTNC--TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYK 289
+T NC T +KP V GL+G+I+ GF + ++ ++E Y K
Sbjct: 22 DTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLK 81
Query: 290 GVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTK 349
+ +V M+SGP VAM + N KT R G +P + +PGT+R F
Sbjct: 82 D-RPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQV 137
Query: 350 IQNAVHCTDLPEDGLLEVQYFF 371
+N +H +D E E+ +F
Sbjct: 138 GRNIIHGSDSVESAEKEIGLWF 159
>gi|4557797 non-metastatic cells 1, protein (NM23A) expressed in
isoform b [Homo sapiens]
Length = 152
Score = 71.2 bits (173), Expect = 1e-12
Identities = 47/150 (31%), Positives = 75/150 (50%), Gaps = 11/150 (7%)
Query: 92 EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149
E+T IKPD + + GEII+ + GF + LK M S + +VD + RPFF L
Sbjct: 5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKDRPFFAGL 64
Query: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209
++++ +GP++AM + + + +LG N ++ +IR F RN HG D
Sbjct: 65 VKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121
Query: 210 SFASAAREMELFFPSSGGCGPANTAKFTNC 239
S SA +E+ L+F P +T+C
Sbjct: 122 SVESAEKEIGLWF------HPEELVDYTSC 145
Score = 54.7 bits (130), Expect = 1e-07
Identities = 40/136 (29%), Positives = 62/136 (45%), Gaps = 6/136 (4%)
Query: 238 NC--TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEY 295
NC T +KP V GL+G+I+ GF + ++ ++E Y K +
Sbjct: 3 NCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASEDLLKEHYVDLKD-RPFF 61
Query: 296 HDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVH 355
+V M+SGP VAM + N KT R G +P + +PGT+R F +N +H
Sbjct: 62 AGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIH 118
Query: 356 CTDLPEDGLLEVQYFF 371
+D E E+ +F
Sbjct: 119 GSDSVESAEKEIGLWF 134
>gi|66392227 nucleoside diphosphate kinase B [Homo sapiens]
Length = 152
Score = 70.5 bits (171), Expect = 2e-12
Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)
Query: 92 EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149
E+T IKPD + + GEII+ + GF + +K + S + ++D + RPFF L
Sbjct: 5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
Query: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209
++++ +GP++AM + + + +LG N ++ +IR F RN HG D
Sbjct: 65 VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121
Query: 210 SFASAAREMELFF 222
S SA +E+ L+F
Sbjct: 122 SVKSAEKEISLWF 134
Score = 56.6 bits (135), Expect = 4e-08
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)
Query: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 299
T +KP V GL+G+I+ GF + AM+ ++++ Y K + +V
Sbjct: 7 TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65
Query: 300 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 359
M SGP VAM + N KT R G +P + +PGT+R F +N +H +D
Sbjct: 66 KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122
Query: 360 PEDGLLEVQYFFK 372
+ E+ +FK
Sbjct: 123 VKSAEKEISLWFK 135
>gi|66392205 nucleoside diphosphate kinase B [Homo sapiens]
Length = 152
Score = 70.5 bits (171), Expect = 2e-12
Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)
Query: 92 EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149
E+T IKPD + + GEII+ + GF + +K + S + ++D + RPFF L
Sbjct: 5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
Query: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209
++++ +GP++AM + + + +LG N ++ +IR F RN HG D
Sbjct: 65 VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121
Query: 210 SFASAAREMELFF 222
S SA +E+ L+F
Sbjct: 122 SVKSAEKEISLWF 134
Score = 56.6 bits (135), Expect = 4e-08
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)
Query: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 299
T +KP V GL+G+I+ GF + AM+ ++++ Y K + +V
Sbjct: 7 TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65
Query: 300 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 359
M SGP VAM + N KT R G +P + +PGT+R F +N +H +D
Sbjct: 66 KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122
Query: 360 PEDGLLEVQYFFK 372
+ E+ +FK
Sbjct: 123 VKSAEKEISLWFK 135
>gi|66392192 nucleoside diphosphate kinase B [Homo sapiens]
Length = 152
Score = 70.5 bits (171), Expect = 2e-12
Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)
Query: 92 EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149
E+T IKPD + + GEII+ + GF + +K + S + ++D + RPFF L
Sbjct: 5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
Query: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209
++++ +GP++AM + + + +LG N ++ +IR F RN HG D
Sbjct: 65 VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121
Query: 210 SFASAAREMELFF 222
S SA +E+ L+F
Sbjct: 122 SVKSAEKEISLWF 134
Score = 56.6 bits (135), Expect = 4e-08
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)
Query: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 299
T +KP V GL+G+I+ GF + AM+ ++++ Y K + +V
Sbjct: 7 TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65
Query: 300 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 359
M SGP VAM + N KT R G +P + +PGT+R F +N +H +D
Sbjct: 66 KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122
Query: 360 PEDGLLEVQYFFK 372
+ E+ +FK
Sbjct: 123 VKSAEKEISLWFK 135
>gi|4505409 nucleoside diphosphate kinase B [Homo sapiens]
Length = 152
Score = 70.5 bits (171), Expect = 2e-12
Identities = 41/133 (30%), Positives = 70/133 (52%), Gaps = 5/133 (3%)
Query: 92 EKTLALIKPDAISKA--GEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNEL 149
E+T IKPD + + GEII+ + GF + +K + S + ++D + RPFF L
Sbjct: 5 ERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKDRPFFPGL 64
Query: 150 IQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPD 209
++++ +GP++AM + + + +LG N ++ +IR F RN HG D
Sbjct: 65 VKYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPG---TIRGDFCIQVGRNIIHGSD 121
Query: 210 SFASAAREMELFF 222
S SA +E+ L+F
Sbjct: 122 SVKSAEKEISLWF 134
Score = 56.6 bits (135), Expect = 4e-08
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 4/133 (3%)
Query: 240 TCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMV 299
T +KP V GL+G+I+ GF + AM+ ++++ Y K + +V
Sbjct: 7 TFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMKFLRASEEHLKQHYIDLKD-RPFFPGLV 65
Query: 300 TEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDL 359
M SGP VAM + N KT R G +P + +PGT+R F +N +H +D
Sbjct: 66 KYMNSGPVVAMVWEGLNVVKTGRVMLGETNPADS---KPGTIRGDFCIQVGRNIIHGSDS 122
Query: 360 PEDGLLEVQYFFK 372
+ E+ +FK
Sbjct: 123 VKSAEKEISLWFK 135
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 31.2 bits (69), Expect = 1.6
Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 4/56 (7%)
Query: 323 EFCGPADPEIARHLRPGTLRAIFGKTKIQ----NAVHCTDLPEDGLLEVQYFFKIL 374
+F G ADP + HL PG +A KTK Q N V DL G+ + K+L
Sbjct: 120 DFNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVL 175
>gi|112363080 microtubule associated serine/threonine kinase 2 [Homo
sapiens]
Length = 1798
Score = 30.0 bits (66), Expect = 3.5
Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 323 EFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN 376
EF P+ L G L I + I+ A C D GL+ QYF+++ DN
Sbjct: 337 EFISSNTPDSVLPLADGALSFIHHQV-IEMARDCLDKSRSGLITSQYFYELQDN 389
>gi|191251777 breast carcinoma amplified sequence 1 [Homo sapiens]
Length = 584
Score = 29.3 bits (64), Expect = 6.0
Identities = 21/57 (36%), Positives = 26/57 (45%), Gaps = 6/57 (10%)
Query: 179 ANSGVARTDASES----IRALFGTDGIRNAAHGP--DSFASAAREMELFFPSSGGCG 229
+N A D SES + A G D + H P D SAAR+ L P +GG G
Sbjct: 125 SNKAPANKDPSESWTLPVAAGPGQDTDKTPGHAPAQDKVLSAARDPTLLPPETGGAG 181
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,567,945
Number of Sequences: 37866
Number of extensions: 554415
Number of successful extensions: 1117
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1041
Number of HSP's gapped (non-prelim): 35
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.