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Search of human proteins with 6912528
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens]
(305 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens] 637 0.0
gi|5729941 tetraspanin 9 [Homo sapiens] 105 5e-23
gi|87159824 CD151 antigen [Homo sapiens] 102 4e-22
gi|87159822 CD151 antigen [Homo sapiens] 102 4e-22
gi|21237751 CD151 antigen [Homo sapiens] 102 4e-22
gi|21237748 CD151 antigen [Homo sapiens] 102 4e-22
gi|68800005 tetraspanin 4 isoform a [Homo sapiens] 97 2e-20
gi|4507543 tetraspanin 4 isoform a [Homo sapiens] 97 2e-20
gi|68800018 tetraspanin 4 isoform a [Homo sapiens] 97 2e-20
gi|68800024 tetraspanin 4 isoform a [Homo sapiens] 97 2e-20
gi|68800011 tetraspanin 4 isoform a [Homo sapiens] 97 2e-20
gi|68799997 tetraspanin 4 isoform a [Homo sapiens] 97 2e-20
gi|4502679 CD63 antigen isoform A [Homo sapiens] 96 3e-20
gi|91199546 CD63 antigen isoform B [Homo sapiens] 94 1e-19
gi|122937466 tetraspanin 11 [Homo sapiens] 91 2e-18
gi|4504813 CD82 antigen isoform 1 [Homo sapiens] 85 7e-17
gi|4502693 CD9 antigen [Homo sapiens] 77 1e-14
gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens] 74 2e-13
gi|68800032 tetraspanin 4 isoform b [Homo sapiens] 73 4e-13
gi|4757944 CD81 antigen [Homo sapiens] 70 2e-12
gi|21265104 tetraspanin 7 [Homo sapiens] 69 5e-12
gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo ... 66 4e-11
gi|67782354 CD82 antigen isoform 2 [Homo sapiens] 65 6e-11
gi|4502663 CD37 antigen isoform A [Homo sapiens] 65 6e-11
gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens] 65 1e-10
gi|21264580 tetraspan 2 [Homo sapiens] 64 1e-10
gi|30425534 tetraspanin 33 [Homo sapiens] 62 8e-10
gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens] 58 9e-09
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens] 57 2e-08
gi|10834972 CD53 antigen [Homo sapiens] 57 2e-08
>gi|6912528 transmembrane 4 superfamily member 12 [Homo sapiens]
Length = 305
Score = 637 bits (1642), Expect = 0.0
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60
MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF
Sbjct: 1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60
Query: 61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELM 120
PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELM
Sbjct: 61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELM 120
Query: 121 VPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDS 180
VPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDS
Sbjct: 121 VPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDS 180
Query: 181 CCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMIL 240
CCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMIL
Sbjct: 181 CCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMIL 240
Query: 241 TITLLWALYYDRREPGTDQMMSLKNDNSQHLSCPSVELLKPSLSRIFEHTSMANSFNTHF 300
TITLLWALYYDRREPGTDQMMSLKNDNSQHLSCPSVELLKPSLSRIFEHTSMANSFNTHF
Sbjct: 241 TITLLWALYYDRREPGTDQMMSLKNDNSQHLSCPSVELLKPSLSRIFEHTSMANSFNTHF 300
Query: 301 EMEEL 305
EMEEL
Sbjct: 301 EMEEL 305
>gi|5729941 tetraspanin 9 [Homo sapiens]
Length = 239
Score = 105 bits (262), Expect = 5e-23
Identities = 71/236 (30%), Positives = 108/236 (45%), Gaps = 17/236 (7%)
Query: 9 CLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMI 68
CL+ +++ NL+FWL +L V W+ N T + A L +I
Sbjct: 8 CLKYMMFLFNLIFWLCGCGLLGVGIWLSVSQGNFATFSPSFPSLSAANL---------VI 58
Query: 69 AVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWSDM 128
A+ +++ G LG G +K N LL +F LLVI EL + + M V +
Sbjct: 59 AIGTIVMVTGFLGCLGAIKENKCLLLSFFIVLLVILLAELILLILFFVY--MDKVNENAK 116
Query: 129 VTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREFPG 188
LK + Y L +AWN Q E +CCGV +TDW + + PD CC+ G
Sbjct: 117 KDLKEGLLLYHTENNVGLKNAWNIIQAEMRCCGVTDYTDWYPVLGENTVPDRCCMENSQG 176
Query: 189 CSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITL 244
C + A + L++ GC +K+ + K VL +G+ I + QIL M ++TL
Sbjct: 177 CGRNA----TTPLWRTGCYEKVKMWFDDNK--HVLGTVGMCILIMQILGMAFSMTL 226
>gi|87159824 CD151 antigen [Homo sapiens]
Length = 253
Score = 102 bits (254), Expect = 4e-22
Identities = 74/253 (29%), Positives = 121/253 (47%), Gaps = 32/253 (12%)
Query: 9 CLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMI 68
CL+ LL+ N FWL ++V+AV W ++ ++L A TY + +++
Sbjct: 15 CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASG--------TYLATAY-ILV 65
Query: 69 AVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVPVQWS 126
+++ G+LG C T K LL YF LL+IF +E+ G+ + Y Q+L ++
Sbjct: 66 VAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELK-- 123
Query: 127 DMVTLKARMT-NYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDW--------- 176
LK MT Y P + +T A + Q+EF CCG DW + +W
Sbjct: 124 --ENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDW---RDSEWIRSQEAGGR 178
Query: 177 -PPDSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQI 235
PDSCC C ++ H ++ + + GC K+ +F++ + L+V+ +GI I Q+
Sbjct: 179 VVPDSCCKTVVALCGQRDHASNIYKV-EGGCITKLETFIQ--EHLRVIGAVGIGIACVQV 235
Query: 236 LAMILTITLLWAL 248
MI T L +L
Sbjct: 236 FGMIFTCCLYRSL 248
>gi|87159822 CD151 antigen [Homo sapiens]
Length = 253
Score = 102 bits (254), Expect = 4e-22
Identities = 74/253 (29%), Positives = 121/253 (47%), Gaps = 32/253 (12%)
Query: 9 CLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMI 68
CL+ LL+ N FWL ++V+AV W ++ ++L A TY + +++
Sbjct: 15 CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASG--------TYLATAY-ILV 65
Query: 69 AVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVPVQWS 126
+++ G+LG C T K LL YF LL+IF +E+ G+ + Y Q+L ++
Sbjct: 66 VAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELK-- 123
Query: 127 DMVTLKARMT-NYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDW--------- 176
LK MT Y P + +T A + Q+EF CCG DW + +W
Sbjct: 124 --ENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDW---RDSEWIRSQEAGGR 178
Query: 177 -PPDSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQI 235
PDSCC C ++ H ++ + + GC K+ +F++ + L+V+ +GI I Q+
Sbjct: 179 VVPDSCCKTVVALCGQRDHASNIYKV-EGGCITKLETFIQ--EHLRVIGAVGIGIACVQV 235
Query: 236 LAMILTITLLWAL 248
MI T L +L
Sbjct: 236 FGMIFTCCLYRSL 248
>gi|21237751 CD151 antigen [Homo sapiens]
Length = 253
Score = 102 bits (254), Expect = 4e-22
Identities = 74/253 (29%), Positives = 121/253 (47%), Gaps = 32/253 (12%)
Query: 9 CLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMI 68
CL+ LL+ N FWL ++V+AV W ++ ++L A TY + +++
Sbjct: 15 CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASG--------TYLATAY-ILV 65
Query: 69 AVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVPVQWS 126
+++ G+LG C T K LL YF LL+IF +E+ G+ + Y Q+L ++
Sbjct: 66 VAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELK-- 123
Query: 127 DMVTLKARMT-NYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDW--------- 176
LK MT Y P + +T A + Q+EF CCG DW + +W
Sbjct: 124 --ENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDW---RDSEWIRSQEAGGR 178
Query: 177 -PPDSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQI 235
PDSCC C ++ H ++ + + GC K+ +F++ + L+V+ +GI I Q+
Sbjct: 179 VVPDSCCKTVVALCGQRDHASNIYKV-EGGCITKLETFIQ--EHLRVIGAVGIGIACVQV 235
Query: 236 LAMILTITLLWAL 248
MI T L +L
Sbjct: 236 FGMIFTCCLYRSL 248
>gi|21237748 CD151 antigen [Homo sapiens]
Length = 253
Score = 102 bits (254), Expect = 4e-22
Identities = 74/253 (29%), Positives = 121/253 (47%), Gaps = 32/253 (12%)
Query: 9 CLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMI 68
CL+ LL+ N FWL ++V+AV W ++ ++L A TY + +++
Sbjct: 15 CLKYLLFTYNCCFWLAGLAVMAVGIWTLALKSDYISLLASG--------TYLATAY-ILV 65
Query: 69 AVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVPVQWS 126
+++ G+LG C T K LL YF LL+IF +E+ G+ + Y Q+L ++
Sbjct: 66 VAGTVVMVTGVLGCCATFKERRNLLRLYFILLLIIFLLEIIAGILAYAYYQQLNTELK-- 123
Query: 127 DMVTLKARMT-NYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDW--------- 176
LK MT Y P + +T A + Q+EF CCG DW + +W
Sbjct: 124 --ENLKDTMTKRYHQPGHEAVTSAVDQLQQEFHCCGSNNSQDW---RDSEWIRSQEAGGR 178
Query: 177 -PPDSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQI 235
PDSCC C ++ H ++ + + GC K+ +F++ + L+V+ +GI I Q+
Sbjct: 179 VVPDSCCKTVVALCGQRDHASNIYKV-EGGCITKLETFIQ--EHLRVIGAVGIGIACVQV 235
Query: 236 LAMILTITLLWAL 248
MI T L +L
Sbjct: 236 FGMIFTCCLYRSL 248
>gi|68800005 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 96.7 bits (239), Expect = 2e-20
Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 25/242 (10%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHP- 65
++ ++ L++A NLLFWL VL V W+ A T+ A + + FP +
Sbjct: 6 LQAVKYLMFAFNLLFWLGGCGVLGVGIWL-----------AATQGSFATLSSSFPSLSAA 54
Query: 66 -VMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVP 122
++I F++ +G +G G +K N LL +F LL++F +E + + Y ++
Sbjct: 55 NLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRY 114
Query: 123 VQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCC 182
Q LK + YG LT+AW+ Q +F+CCGV +TDW E+ PDSCC
Sbjct: 115 AQQD----LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCC 170
Query: 183 VREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTI 242
+ C A ++ C + + +L+ + L + G+ + QIL + +
Sbjct: 171 LEFSESCGLHAP----GTWWKAPCYETVKVWLQ--ENLLAVGIFGLCTALVQILGLTFAM 224
Query: 243 TL 244
T+
Sbjct: 225 TM 226
>gi|4507543 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 96.7 bits (239), Expect = 2e-20
Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 25/242 (10%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHP- 65
++ ++ L++A NLLFWL VL V W+ A T+ A + + FP +
Sbjct: 6 LQAVKYLMFAFNLLFWLGGCGVLGVGIWL-----------AATQGSFATLSSSFPSLSAA 54
Query: 66 -VMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVP 122
++I F++ +G +G G +K N LL +F LL++F +E + + Y ++
Sbjct: 55 NLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRY 114
Query: 123 VQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCC 182
Q LK + YG LT+AW+ Q +F+CCGV +TDW E+ PDSCC
Sbjct: 115 AQQD----LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCC 170
Query: 183 VREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTI 242
+ C A ++ C + + +L+ + L + G+ + QIL + +
Sbjct: 171 LEFSESCGLHAP----GTWWKAPCYETVKVWLQ--ENLLAVGIFGLCTALVQILGLTFAM 224
Query: 243 TL 244
T+
Sbjct: 225 TM 226
>gi|68800018 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 96.7 bits (239), Expect = 2e-20
Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 25/242 (10%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHP- 65
++ ++ L++A NLLFWL VL V W+ A T+ A + + FP +
Sbjct: 6 LQAVKYLMFAFNLLFWLGGCGVLGVGIWL-----------AATQGSFATLSSSFPSLSAA 54
Query: 66 -VMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVP 122
++I F++ +G +G G +K N LL +F LL++F +E + + Y ++
Sbjct: 55 NLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRY 114
Query: 123 VQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCC 182
Q LK + YG LT+AW+ Q +F+CCGV +TDW E+ PDSCC
Sbjct: 115 AQQD----LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCC 170
Query: 183 VREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTI 242
+ C A ++ C + + +L+ + L + G+ + QIL + +
Sbjct: 171 LEFSESCGLHAP----GTWWKAPCYETVKVWLQ--ENLLAVGIFGLCTALVQILGLTFAM 224
Query: 243 TL 244
T+
Sbjct: 225 TM 226
>gi|68800024 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 96.7 bits (239), Expect = 2e-20
Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 25/242 (10%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHP- 65
++ ++ L++A NLLFWL VL V W+ A T+ A + + FP +
Sbjct: 6 LQAVKYLMFAFNLLFWLGGCGVLGVGIWL-----------AATQGSFATLSSSFPSLSAA 54
Query: 66 -VMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVP 122
++I F++ +G +G G +K N LL +F LL++F +E + + Y ++
Sbjct: 55 NLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRY 114
Query: 123 VQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCC 182
Q LK + YG LT+AW+ Q +F+CCGV +TDW E+ PDSCC
Sbjct: 115 AQQD----LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCC 170
Query: 183 VREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTI 242
+ C A ++ C + + +L+ + L + G+ + QIL + +
Sbjct: 171 LEFSESCGLHAP----GTWWKAPCYETVKVWLQ--ENLLAVGIFGLCTALVQILGLTFAM 224
Query: 243 TL 244
T+
Sbjct: 225 TM 226
>gi|68800011 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 96.7 bits (239), Expect = 2e-20
Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 25/242 (10%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHP- 65
++ ++ L++A NLLFWL VL V W+ A T+ A + + FP +
Sbjct: 6 LQAVKYLMFAFNLLFWLGGCGVLGVGIWL-----------AATQGSFATLSSSFPSLSAA 54
Query: 66 -VMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVP 122
++I F++ +G +G G +K N LL +F LL++F +E + + Y ++
Sbjct: 55 NLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRY 114
Query: 123 VQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCC 182
Q LK + YG LT+AW+ Q +F+CCGV +TDW E+ PDSCC
Sbjct: 115 AQQD----LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCC 170
Query: 183 VREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTI 242
+ C A ++ C + + +L+ + L + G+ + QIL + +
Sbjct: 171 LEFSESCGLHAP----GTWWKAPCYETVKVWLQ--ENLLAVGIFGLCTALVQILGLTFAM 224
Query: 243 TL 244
T+
Sbjct: 225 TM 226
>gi|68799997 tetraspanin 4 isoform a [Homo sapiens]
Length = 238
Score = 96.7 bits (239), Expect = 2e-20
Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 25/242 (10%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHP- 65
++ ++ L++A NLLFWL VL V W+ A T+ A + + FP +
Sbjct: 6 LQAVKYLMFAFNLLFWLGGCGVLGVGIWL-----------AATQGSFATLSSSFPSLSAA 54
Query: 66 -VMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVP 122
++I F++ +G +G G +K N LL +F LL++F +E + + Y ++
Sbjct: 55 NLLIITGAFVMAIGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRY 114
Query: 123 VQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCC 182
Q LK + YG LT+AW+ Q +F+CCGV +TDW E+ PDSCC
Sbjct: 115 AQQD----LKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCC 170
Query: 183 VREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTI 242
+ C A ++ C + + +L+ + L + G+ + QIL + +
Sbjct: 171 LEFSESCGLHAP----GTWWKAPCYETVKVWLQ--ENLLAVGIFGLCTALVQILGLTFAM 224
Query: 243 TL 244
T+
Sbjct: 225 TM 226
>gi|4502679 CD63 antigen isoform A [Homo sapiens]
Length = 238
Score = 96.3 bits (238), Expect = 3e-20
Identities = 70/247 (28%), Positives = 122/247 (49%), Gaps = 21/247 (8%)
Query: 1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60
MA E +KC++ LLY L L F ++ ++AV + L+ +T ++ A +
Sbjct: 1 MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLS-------QTIIQGATPGSLL 53
Query: 61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELM 120
PVV +IAV FL +V +G CG K N L+ + L +I VE+A + Y
Sbjct: 54 PVV---IIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDK 110
Query: 121 VPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEM--DWPP 178
V ++++ + +M NY P+ + Q +FKCCG +TDW ++ M + P
Sbjct: 111 VMSEFNN--NFRQQMENY--PKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVP 166
Query: 179 DSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAM 238
DSCC+ GC +++ +++EGC +K+ +LR K + V+ + I ++L +
Sbjct: 167 DSCCINVTVGCGINFNEK---AIHKEGCVEKIGGWLR--KNVLVVAAAALGIAFVEVLGI 221
Query: 239 ILTITLL 245
+ L+
Sbjct: 222 VFACCLV 228
>gi|91199546 CD63 antigen isoform B [Homo sapiens]
Length = 236
Score = 94.4 bits (233), Expect = 1e-19
Identities = 70/247 (28%), Positives = 121/247 (48%), Gaps = 23/247 (9%)
Query: 1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60
MA E +KC++ LLY L L F ++ ++AV + L+ +T ++ A +
Sbjct: 1 MAVEGGMKCVKFLLYVLLLAFCACAVGLIAVGVGAQLVLS-------QTIIQGATPGSLL 53
Query: 61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELM 120
PVV +IAV FL +V +G CG K N L+ + L +I VE+A + Y
Sbjct: 54 PVV---IIAVGVFLFLVAFVGCCGACKENYCLMITFAIFLSLIMLVEVAAAIAGYVFRDK 110
Query: 121 VPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEM--DWPP 178
V ++++ + +M NY P+ + Q +FKCCG +TDW ++ M + P
Sbjct: 111 VMSEFNN--NFRQQMENY--PKNNHTASILDRMQADFKCCGAANYTDWEKIPSMSKNRVP 166
Query: 179 DSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAM 238
DSCC+ GC +++ +++EGC +K+ +LR VL ++G+ +L +
Sbjct: 167 DSCCINVTVGCGINFNEK---AIHKEGCVEKIGGWLR----KNVLVVAAAALGIAFVLGI 219
Query: 239 ILTITLL 245
+ L+
Sbjct: 220 VFACCLV 226
>gi|122937466 tetraspanin 11 [Homo sapiens]
Length = 253
Score = 90.5 bits (223), Expect = 2e-18
Identities = 73/244 (29%), Positives = 108/244 (44%), Gaps = 24/244 (9%)
Query: 10 LRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIA 69
L+ LL+ N FW+ +VLAV W + L++ A + + + F V
Sbjct: 16 LKYLLFVFNFFFWVGGAAVLAVGIWTLVEKSGYLSVLASSTFAASAYILIFAGV------ 69
Query: 70 VCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWT--YEQELMVPVQWSD 127
+++ G LG+ + L+ YF LLVIF VEL GV Y Q L ++
Sbjct: 70 ---LVMVTGFLGFGAILWERKGCLSTYFCLLLVIFLVELVAGVLAHVYYQRLSDELKQHL 126
Query: 128 MVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDW-------LEMTEMDWPPDS 180
TL NYG P +T + + Q++FKCCG DW L E PDS
Sbjct: 127 NRTLAE---NYGQPGATQITASVDRLQQDFKCCGSNSSADWQHSTYILLREAEGRQVPDS 183
Query: 181 CCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMIL 240
CC C ++AH ++ + + GC K+ FL L ++ +GI + QI M+L
Sbjct: 184 CCKTVVVRCGQRAHPSNIYKV-EGGCLTKLEQFL--ADHLLLMGAVGIGVACLQICGMVL 240
Query: 241 TITL 244
T L
Sbjct: 241 TCCL 244
>gi|4504813 CD82 antigen isoform 1 [Homo sapiens]
Length = 267
Score = 85.1 bits (209), Expect = 7e-17
Identities = 70/259 (27%), Positives = 121/259 (46%), Gaps = 33/259 (12%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPV 66
+K + L+ NL+F+++ +L W+ ++ +++ +T + Y V
Sbjct: 6 IKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVL-QTSSSSLRMGAY------V 58
Query: 67 MIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWS 126
I V +++G LG G V LL YF LL+I ++ G Y + +
Sbjct: 59 FIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMG 118
Query: 127 DMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTE-MDWP----PDSC 181
+VT R +Y R L AW++ Q + KCCG V F +W + E M+ P P SC
Sbjct: 119 GIVTELIR--DYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSC 176
Query: 182 CVR--------------EFPGCSKQA--HQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRF 225
V+ E PG Q+ H ED +YQEGC +K+ ++L+ + L ++
Sbjct: 177 EVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDW-PVYQEGCMEKVQAWLQ--ENLGIILG 233
Query: 226 LGISIGVTQILAMILTITL 244
+G+ + + ++L M+L+I L
Sbjct: 234 VGVGVAIIELLGMVLSICL 252
>gi|4502693 CD9 antigen [Homo sapiens]
Length = 228
Score = 77.4 bits (189), Expect = 1e-14
Identities = 38/118 (32%), Positives = 64/118 (54%), Gaps = 4/118 (3%)
Query: 1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60
M + KC++ LL+ N +FWL I+VLA+ W+R ET + +++
Sbjct: 1 MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNS---SFY 57
Query: 61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQE 118
V+ ++I +++VG LG CG V+ + +L +FG LLVIF +E+A +W Y +
Sbjct: 58 TGVY-ILIGAGALMMLVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHK 114
>gi|4759238 transmembrane 4 superfamily member 3 [Homo sapiens]
Length = 237
Score = 73.6 bits (179), Expect = 2e-13
Identities = 62/244 (25%), Positives = 111/244 (45%), Gaps = 28/244 (11%)
Query: 9 CLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMI 68
C++ ++ N LFWL I +LA++ W+R ++ +E + + ++I
Sbjct: 7 CIKYSMFTFNFLFWLCGILILALAIWVRVSNDSQAIFGSEDVGSSSYVAV------DILI 60
Query: 69 AVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWSDM 128
AV ++I+G LG CG +K + +L +F LL+I +++A G+ V SD
Sbjct: 61 AVGAIIMILGFLGCCGAIKESRCMLLLFFIGLLLILLLQVATGILG-----AVFKSKSDR 115
Query: 129 VTLKARMTNYGL-----PRYRWLTHAWNFFQREFKCCGVVY-FTDWLEMTEMDWPPDSCC 182
+ + N L + A FQ EFKCCG+V DW + +P C
Sbjct: 116 IVNETLYENTKLLSATGESEKQFQEAIIVFQEEFKCCGLVNGAADWGNNFQ-HYPELCAC 174
Query: 183 VREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIG--VTQILAMIL 240
+ + C ++ +Y+E C SF++ ++ +GIS G V +IL ++
Sbjct: 175 LDKQRPCQSYNGKQ----VYKETC----ISFIKDFLAKNLIIVIGISFGLAVIEILGLVF 226
Query: 241 TITL 244
++ L
Sbjct: 227 SMVL 230
>gi|68800032 tetraspanin 4 isoform b [Homo sapiens]
Length = 174
Score = 72.8 bits (177), Expect = 4e-13
Identities = 47/170 (27%), Positives = 79/170 (46%), Gaps = 12/170 (7%)
Query: 77 VGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGV--WTYEQELMVPVQWSDMVTLKAR 134
+G +G G +K N LL +F LL++F +E + + Y ++ Q LK
Sbjct: 3 IGFVGCLGAIKENKCLLLTFFLLLLLVFLLEATIAILFFAYTDKIDRYAQQD----LKKG 58
Query: 135 MTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREFPGCSKQAH 194
+ YG LT+AW+ Q +F+CCGV +TDW E+ PDSCC+ C A
Sbjct: 59 LHLYGTQGNVGLTNAWSIIQTDFRCCGVSNYTDWFEVYNATRVPDSCCLEFSESCGLHAP 118
Query: 195 QEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITL 244
++ C + + +L+ + L + G+ + QIL + +T+
Sbjct: 119 ----GTWWKAPCYETVKVWLQ--ENLLAVGIFGLCTALVQILGLTFAMTM 162
>gi|4757944 CD81 antigen [Homo sapiens]
Length = 236
Score = 70.1 bits (170), Expect = 2e-12
Identities = 63/258 (24%), Positives = 102/258 (39%), Gaps = 46/258 (17%)
Query: 1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60
M E KC++ LL+ N +FWL +L V+ W+R L E + A Y
Sbjct: 1 MGVEGCTKCIKYLLFVFNFVFWLAGGVILGVALWLRHDPQTTNLLYLELGDKPAPNTFYV 60
Query: 61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVW------- 113
+ ++IAV ++ VG LG G ++ + LL +F L+++F E+A G+W
Sbjct: 61 GIY--ILIAVGAVMMFVGFLGCYGAIQESQCLLGTFFTCLVILFACEVAAGIWGFVNKDQ 118
Query: 114 -------TYEQELMVPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFT 166
Y+Q L V D KA + F CCG T
Sbjct: 119 IAKDVKQFYDQALQQAVVDDDANNAKAVVKT---------------FHETLDCCGSSTLT 163
Query: 167 DWLEMTEMDWPPDSCCVREFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFL 226
+T + C + +S+L++E C +K+ G +L ++
Sbjct: 164 ---ALTTSVLKNNLC----------PSGSNIISNLFKEDCHQKIDDLFSG--KLYLIGIA 208
Query: 227 GISIGVTQILAMILTITL 244
I + V I MIL++ L
Sbjct: 209 AIVVAVIMIFEMILSMVL 226
>gi|21265104 tetraspanin 7 [Homo sapiens]
Length = 249
Score = 68.9 bits (167), Expect = 5e-12
Identities = 58/249 (23%), Positives = 103/249 (41%), Gaps = 22/249 (8%)
Query: 1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYF 60
M + + CL+ LL + +FW+ + +LAV W + L ++L AE +L
Sbjct: 6 METKPVITCLKTLLIIYSFVFWITGVILLAVGVWGKLTLGTYISLIAENSTNAPYVL--- 62
Query: 61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELM 120
I +++ G+ G T + + +L Y L ++F EL G+ +
Sbjct: 63 -------IGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGISGFVFRHE 115
Query: 121 VPVQWSDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLE---MTEMDWP 177
+ + T + N R R + H QR CCGV +T+W E P
Sbjct: 116 IKDTFLRTYTDAMQTYNGNDERSRAVDHV----QRSLSCCGVQNYTNWSTSPYFLEHGIP 171
Query: 178 PDSCCVREFPGCSKQAHQEDL--SDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQI 235
P SCC+ E + H + + + Q+GC + SF+ + ++ + I +Q+
Sbjct: 172 P-SCCMNETDCNPQDLHNLTVAATKVNQKGCYDLVTSFME--TNMGIIAGVAFGIAFSQL 228
Query: 236 LAMILTITL 244
+ M+L L
Sbjct: 229 IGMLLACCL 237
>gi|5032201 transmembrane 4 superfamily member 8 isoform 1 [Homo
sapiens]
Length = 253
Score = 65.9 bits (159), Expect = 4e-11
Identities = 64/241 (26%), Positives = 106/241 (43%), Gaps = 22/241 (9%)
Query: 11 RCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAV 70
+ +L LNL+FW + + V A++ +T E V T P V V+IAV
Sbjct: 10 KTVLVFLNLIFWGAAGILCYVGAYV------FITYDDYDHFFEDVY-TLIPAV--VIIAV 60
Query: 71 CCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWSDMVT 130
L I+G++G C T++ + LA + LL++F E+ V Y V + +
Sbjct: 61 GALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQ 120
Query: 131 LKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYF-----TDWLEMTEMDWPPDSCCVRE 185
+ N P + A ++ QR+ CCG+ + TDW + T+ P SCC
Sbjct: 121 KVYKTYNGTNPDA--ASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRET 178
Query: 186 FPGCS-KQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITL 244
C+ AH SDLY EGC + L+ + + + + ++ Q+L M+ +
Sbjct: 179 ASNCNGSLAHP---SDLYAEGCEALVVKKLQ--EIMMHVIWAALAFAAIQLLGMLCACIV 233
Query: 245 L 245
L
Sbjct: 234 L 234
>gi|67782354 CD82 antigen isoform 2 [Homo sapiens]
Length = 242
Score = 65.5 bits (158), Expect = 6e-11
Identities = 65/259 (25%), Positives = 115/259 (44%), Gaps = 58/259 (22%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPV 66
+K + L+ NL+F+++ +L W+ ++ +++ +T + Y V
Sbjct: 6 IKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVL-QTSSSSLRMGAY------V 58
Query: 67 MIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWS 126
I V +++G LG G V E+ C + +QE+
Sbjct: 59 FIGVGAVTMLMGFLGCIGAVN-------------------EVRCLLGLLKQEM------G 93
Query: 127 DMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTE-MDWP----PDSC 181
+VT R +Y R L AW++ Q + KCCG V F +W + E M+ P P SC
Sbjct: 94 GIVTELIR--DYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSC 151
Query: 182 CVR--------------EFPGCSKQA--HQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRF 225
V+ E PG Q+ H ED +YQEGC +K+ ++L+ + L ++
Sbjct: 152 EVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDW-PVYQEGCMEKVQAWLQ--ENLGIILG 208
Query: 226 LGISIGVTQILAMILTITL 244
+G+ + + ++L M+L+I L
Sbjct: 209 VGVGVAIIELLGMVLSICL 227
>gi|4502663 CD37 antigen isoform A [Homo sapiens]
Length = 281
Score = 65.5 bits (158), Expect = 6e-11
Identities = 59/278 (21%), Positives = 115/278 (41%), Gaps = 51/278 (18%)
Query: 2 AREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFP 61
A+E + ++ L+ NL F+++ + W+ L +T V L + P
Sbjct: 3 AQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWI---------LIDKTSFVSFVGLAFVP 53
Query: 62 V-VHPVMIAVC-CFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQEL 119
+ + ++A+ F + + +LG G +K LL YFG LL++F ++ G+ Q
Sbjct: 54 LQIWSKVLAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRA 113
Query: 120 MVPVQWSDMV--TLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEM------ 171
+ D+V T++ TN P +W++ Q + +CCG Y DW ++
Sbjct: 114 QLERSLRDVVEKTIQKYGTN---PEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGN 170
Query: 172 -TEMDWPPDSCC------------------VREFPGCSKQAHQEDL------SDLYQEGC 206
+E P SC + ++ H D+ S +Y+EGC
Sbjct: 171 GSEAHRVPCSCYNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGC 230
Query: 207 GKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITL 244
+ + +L ++ +GI +GV + +T+++
Sbjct: 231 AQGLQKWLHN----NLISIVGICLGVGLLELGFMTLSI 264
>gi|4507541 transmembrane 4 superfamily member 6 [Homo sapiens]
Length = 245
Score = 64.7 bits (156), Expect = 1e-10
Identities = 57/250 (22%), Positives = 101/250 (40%), Gaps = 22/250 (8%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPV 66
+ C + +L +FW+ + +LAV W + L N +L E V V
Sbjct: 14 ITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATN----------VPFV 63
Query: 67 MIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWS 126
+IA +I++G G T + + +L Y L ++F VEL + + + +
Sbjct: 64 LIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHEIKNSFK 123
Query: 127 DMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWP--PDSCCVR 184
+ + N YR +HA + Q CCGV + DW + P SCC
Sbjct: 124 NNYEKALKQYN-STGDYR--SHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKL 180
Query: 185 EFPGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITL 244
E C+ Q D + EGC K+ + + ++ V+ + + Q++ + L L
Sbjct: 181 E--DCTP---QRDADKVNNEGCFIKVMTIIE--SEMGVVAGISFGVACFQLIGIFLAYCL 233
Query: 245 LWALYYDRRE 254
A+ ++ E
Sbjct: 234 SRAITNNQYE 243
>gi|21264580 tetraspan 2 [Homo sapiens]
Length = 221
Score = 64.3 bits (155), Expect = 1e-10
Identities = 62/246 (25%), Positives = 104/246 (42%), Gaps = 35/246 (14%)
Query: 7 VKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPV 66
++C++ LL NLLFWL +V+A W R + + L++E + E YF V V
Sbjct: 8 LRCIKYLLLGFNLLFWLAGSAVIAFGLWFR-FGGAIKELSSEDKSPE-----YFYVGLYV 61
Query: 67 MIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWS 126
++ ++ VG G CG ++ + +L +F LLVIF E+ GV+ + + V
Sbjct: 62 LVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAF---IGKGVAIR 118
Query: 127 DMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREF 186
+ T+ N L F F+CCG E +E P C +E
Sbjct: 119 HVQTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCG-------KESSEQVQP---TCPKEL 168
Query: 187 PGCSKQAHQEDLSDLYQEGCGKKMYSFLRGTKQLQVLRFLGISIGVTQILAMILTITLLW 246
G + C ++ + + + +LQ++ +GI I I MI ++ L
Sbjct: 169 LG--------------HKNCIDEIETII--SVKLQLIGIVGIGIAGLTIFGMIFSMVLCC 212
Query: 247 ALYYDR 252
A+ R
Sbjct: 213 AIRNSR 218
>gi|30425534 tetraspanin 33 [Homo sapiens]
Length = 283
Score = 61.6 bits (148), Expect = 8e-10
Identities = 60/261 (22%), Positives = 118/261 (45%), Gaps = 46/261 (17%)
Query: 10 LRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIA 69
++ LL+ N+LFW++S+ ++AV + R + + A V+ A++L +++
Sbjct: 22 VKYLLFFFNMLFWVISMVMVAVGVYAR-LMKHAEAALACLAVDPAILL--------IVVG 72
Query: 70 VCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWSDMV 129
V FL+ G G+++ N+ LL + L +F ++LA G+ + +SD
Sbjct: 73 VLMFLLT--FCGCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGF--------VFSDKA 122
Query: 130 TLK-ARMTNYGLPRYR---WLTHAWNFFQREFKCCGVVYFTDWLE-----------MTEM 174
K + + N + YR L + +F Q++F CCG + + DW + E
Sbjct: 123 RGKVSEIINNAIVHYRDDLDLQNLIDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRER 182
Query: 175 DWPPDSCC--------VREFPGCSKQA--HQEDLSDLYQEGCGKKMYSFLRGTKQLQVLR 224
P SCC + G QA + E +Y GC K+ +++ L +L
Sbjct: 183 CSVPYSCCLPTPDQAVINTMCGQGMQAFDYLEASKVIYTNGCIDKLVNWIH--SNLFLLG 240
Query: 225 FLGISIGVTQILAMILTITLL 245
+ + + + Q++ ++L+ L+
Sbjct: 241 GVALGLAIPQLVGILLSQILV 261
>gi|21264583 transmembrane 4 superfamily member 9 [Homo sapiens]
Length = 268
Score = 58.2 bits (139), Expect = 9e-09
Identities = 61/261 (23%), Positives = 108/261 (41%), Gaps = 40/261 (15%)
Query: 9 CLRCLLYALNLLFWLMSISVLAVSAWM---RDYLNNVLTLTAETRVEEAVILTYFPVVHP 65
C++ ++ N++FW + I+ L + W + L+N+ ++T + + F VV
Sbjct: 14 CIKYFIFGFNVIFWFLGITFLGIGLWAWNEKGVLSNISSITDLGGFDPVWL---FLVVGG 70
Query: 66 VMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQW 125
VM I+G G G ++ N LL ++ L +IF +EL GV + + + Q
Sbjct: 71 VM-------FILGFAGCIGALRENTFLLKFFSVFLGIIFFLELTAGVLAFVFKDWIKDQL 123
Query: 126 SDMVTLKARMTNYGLPRYRWLTHAWNFFQREFKCCGV---------VYF--TDWLEMTEM 174
+ R + L + +F Q ++CCG +YF TD E
Sbjct: 124 YFFINNNIRAYRDDID----LQNLIDFTQEYWQCCGAFGADDWNLNIYFNCTDSNASRER 179
Query: 175 DWPPDSCCVRE------FPGCSKQAHQEDLSD----LYQEGCGKKMYSFLRGTKQLQVLR 224
P SCC ++ C A Q+ D +Y +GC + +L+ L ++
Sbjct: 180 CGVPFSCCTKDPAEDVINTQCGYDARQKPEVDQQIVIYTKGCVPQFEKWLQ--DNLTIVA 237
Query: 225 FLGISIGVTQILAMILTITLL 245
+ I I + QI + L L+
Sbjct: 238 GIFIGIALLQIFGICLAQNLV 258
>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
Length = 270
Score = 57.4 bits (137), Expect = 2e-08
Identities = 59/254 (23%), Positives = 107/254 (42%), Gaps = 34/254 (13%)
Query: 13 LLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFPVVHPVMIAVCC 72
LL++ N++FWL + L V W + LT TR+ PVV +M+ V
Sbjct: 18 LLFSYNIIFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRMHGID-----PVVLVLMVGVVM 72
Query: 73 FLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVELACGVWTYEQELMVPVQWSDMVTLK 132
F + G G G ++ N+ LL ++ G++++IF +ELA V + + V ++ +
Sbjct: 73 FTL--GFAGCVGALRENICLLNFFCGTIVLIFFLELAVAVLAFLFQDWVRDRFREFFESN 130
Query: 133 ARMTNYGLPRYRWLTHAWNFFQREFKCCGVVYFTDW-----------LEMTEMDWPPDSC 181
+ + L + + Q+ +CCG DW E P SC
Sbjct: 131 IKSYRDDID----LQNLIDSLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSC 186
Query: 182 CVRE------FPGCSKQAHQEDLS----DLYQEGCGKKMYSFLRGTKQLQVLRFLGISIG 231
CV + C + S ++ +GC + + S+L + + ++ + I+I
Sbjct: 187 CVPDPAQKVVNTQCGYDVRIQLKSKWDESIFTKGCIQALESWL--PRNIYIVAGVFIAIS 244
Query: 232 VTQILAMILTITLL 245
+ QI + L TL+
Sbjct: 245 LLQIFGIFLARTLI 258
>gi|10834972 CD53 antigen [Homo sapiens]
Length = 219
Score = 57.4 bits (137), Expect = 2e-08
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 34/196 (17%)
Query: 6 SVKCLRCLLYALNLLFWLMSISVLAVSAWMRDYLNNVLTLTAETRVEEAVILTYFP--VV 63
S+K L+ +L+ NLLFW+ +L ++ + N V+ P +
Sbjct: 5 SLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNF------------GVLFHNLPSLTL 52
Query: 64 HPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGSLLVIFCVE--LACGVWTYEQELMV 121
V + V +++V LG G++K N LL +F LL+I E LA ++ YEQ+L
Sbjct: 53 GNVFVIVGSIIMVVAFLGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNE 112
Query: 122 PVQWSDMVTLKARMTNYGLPRY---RWLTHAWNFFQREFKCCGVVYFTDWLEMTEMDWPP 178
V A+ + RY AW+ Q +CCG+ +DW PP
Sbjct: 113 YV---------AKGLTDSIHRYHSDNSTKAAWDSIQSFLQCCGINGTSDW-----TSGPP 158
Query: 179 DSC-CVREFPGCSKQA 193
SC R+ GC +A
Sbjct: 159 ASCPSDRKVEGCYAKA 174
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.139 0.457
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,439,676
Number of Sequences: 37866
Number of extensions: 465849
Number of successful extensions: 1350
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1236
Number of HSP's gapped (non-prelim): 59
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.