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Search of human proteins with 6912326
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912326 family with sequence similarity 50, member B [Homo
sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912326 family with sequence similarity 50, member B [Homo sa... 648 0.0
gi|4758220 XAP-5 protein [Homo sapiens] 518 e-147
gi|148746195 trichohyalin [Homo sapiens] 57 3e-08
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 56 5e-08
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 52 7e-07
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 52 7e-07
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 52 7e-07
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 52 7e-07
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 52 7e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 51 1e-06
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 50 3e-06
gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 49 5e-06
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 49 6e-06
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 49 6e-06
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 49 6e-06
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 49 6e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 49 6e-06
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 49 8e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 1e-05
gi|109150435 ankyrin repeat and zinc finger domain containing 1 ... 48 1e-05
gi|109150425 ankyrin repeat and zinc finger domain containing 1 ... 48 1e-05
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 48 1e-05
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 48 1e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 47 2e-05
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 47 2e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 47 2e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 47 2e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 47 3e-05
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 47 3e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 47 3e-05
>gi|6912326 family with sequence similarity 50, member B [Homo
sapiens]
Length = 325
Score = 648 bits (1672), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60
MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL
Sbjct: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60
Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120
KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL
Sbjct: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120
Query: 121 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV 180
SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV
Sbjct: 121 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV 180
Query: 181 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE 240
KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE
Sbjct: 181 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE 240
Query: 241 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK 300
DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK
Sbjct: 241 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK 300
Query: 301 NKHIFPASRWEAYDPEKKWDKYTIR 325
NKHIFPASRWEAYDPEKKWDKYTIR
Sbjct: 301 NKHIFPASRWEAYDPEKKWDKYTIR 325
>gi|4758220 XAP-5 protein [Homo sapiens]
Length = 339
Score = 518 bits (1334), Expect = e-147
Identities = 252/339 (74%), Positives = 296/339 (87%), Gaps = 14/339 (4%)
Query: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60
MAQYKG EAGRAMHL+KKRE+QREQME +KQRIAEE I+KS +DK+FSAHYDAVEAEL
Sbjct: 1 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL 60
Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120
KSSTVGLVTLNDMKA+QEALV+ERE+QLAK++ +E +++ E+ RE+E+++E KRKIS L
Sbjct: 61 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL 120
Query: 121 SFALDDLDDQADAAE--------------ARRAGNLGKNPDVDTSFLPDRDREEEENRLR 166
SF L++ ++ + E + LGKNPDVDTSFLPDRDREEEENRLR
Sbjct: 121 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR 180
Query: 167 EELRQEWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLE 226
EELRQEWEA++EK+K EE+E+TFSYWDGSGHRRTV++RKGNT+QQFL+KAL+ LRKDF E
Sbjct: 181 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE 240
Query: 227 LRSAGVEQLMFIKEDLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDE 286
LRSAGVEQLM+IKEDLI+PH+H+FYDFI+ +ARGKSGPLF+FDVHDDVRLLSDAT+EKDE
Sbjct: 241 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE 300
Query: 287 SHAGKVVLRSWYEKNKHIFPASRWEAYDPEKKWDKYTIR 325
SHAGKVVLRSWYEKNKHIFPASRWE YDPEKKWDKYTIR
Sbjct: 301 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR 339
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 56.6 bits (135), Expect = 3e-08
Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 36/219 (16%)
Query: 13 RAMHLLKKRERQR------EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVG 66
R LLK+ E +R EQ E L+QR+ E + + + ++R E E +
Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633
Query: 67 LVTLNDMKARQEALVRERE----------------RQLAKRQHLEEQRLQQERQREQEQR 110
L + + RQ+ L RE++ Q KR+H EE+R Q+ + EQEQ
Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693
Query: 111 RER-KRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREEL 169
RER K +I + L+ +ADA +++ K R +E+EE R R E
Sbjct: 694 RERIKSRIPKWQW---QLESEADARQSKVYSRPRKQEG------QRRRQEQEEKRRRRES 744
Query: 170 RQEW---EAQREKVKDEEMEVTFSYWDGSGHRRTVRVRK 205
+W E + ++EE F+ W ++ R R+
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFT-WQWQAEEKSERGRQ 782
Score = 55.8 bits (133), Expect = 5e-08
Identities = 54/189 (28%), Positives = 89/189 (47%), Gaps = 20/189 (10%)
Query: 8 MREAGRAMHLLKKRERQRE--QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65
+R GR ++RERQ Q E K+ ET+L+ + +K + EL+
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK-LQEEEPQRQRELQEEEE 276
Query: 66 GLVTLNDMKARQEALVRE-------RERQLAKRQHLEEQRLQQERQREQEQRRERKRKIS 118
L L + R+E E RE+QL ++Q EE+R QQE +REQ++RRE++ +
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE-EERREQQEERREQQERREQQEERR 335
Query: 119 CLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQRE 178
+ E RR L + + + R RE+EE R ++LR+E + +RE
Sbjct: 336 EQQLRREQ--------EERREQQLRREQEEERREQQLR-REQEEERREQQLRREQQLRRE 386
Query: 179 KVKDEEMEV 187
+ E ++
Sbjct: 387 QQLRREQQL 395
Score = 51.6 bits (122), Expect = 9e-07
Identities = 49/177 (27%), Positives = 82/177 (46%), Gaps = 33/177 (18%)
Query: 13 RAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLND 72
R LLK+ E +R + E +QR+ E Q ++R + LK +
Sbjct: 545 RREQLLKREEEKRLEQERREQRLKRE-----QEERR--------DQLLK---------RE 582
Query: 73 MKARQEALVRERERQLAKRQHLEE-QRLQQERQREQEQRRERKRKISCLSFALDDLDDQA 131
+ RQ+ L RE+E +L +R EE +RL+QE +REQ +RE + + ++
Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642
Query: 132 DAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR--EKVKDEEME 186
+ RR + + REEEE RL + L++E E +R +++ +EE E
Sbjct: 643 RQQQLRREQQERREQRL--------KREEEEERLEQRLKREHEEERREQELAEEEQE 691
Score = 51.2 bits (121), Expect = 1e-06
Identities = 45/180 (25%), Positives = 87/180 (48%), Gaps = 17/180 (9%)
Query: 13 RAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLND 72
R L++RERQ + E L+Q EE +L + + R +E + + +
Sbjct: 1038 REKRRLQERERQYREEEELQQE--EEQLLGEERETR---RRQELERQYRKE-------EE 1085
Query: 73 MKARQEALVRE----RERQLAKRQHLEEQRLQQ-ERQREQEQRRERKRKISCLSFALDDL 127
++ +E L+RE R RQ +RQ EE+ LQQ E Q +E+R +R+R+ + ++
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 128 DDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEV 187
Q + R + +++ + + + ++EE +L E +++ +RE+ EE E+
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL 1205
Score = 50.4 bits (119), Expect = 2e-06
Identities = 52/218 (23%), Positives = 101/218 (46%), Gaps = 23/218 (10%)
Query: 23 RQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALVR 82
RQR++ + ++R AEE L+S D + + L+ L K R+E +
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE----LLELR-RKGREEKQQQ 229
Query: 83 ERERQ-----------LAKRQHL---EEQRLQQE---RQREQEQRRERKRKISCLSFALD 125
RERQ KR+ + EE++LQ+E RQRE ++ E+ RK+ +
Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEM 185
+++ RR L + + + + RE++E R ++E R+E + +RE+ + E
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349
Query: 186 EVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKD 223
++ + ++ R ++ +Q L++ Q LR++
Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLRRE-QQLRRE 386
Score = 50.1 bits (118), Expect = 3e-06
Identities = 45/169 (26%), Positives = 84/169 (49%), Gaps = 20/169 (11%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
++R +++E+ E L+QR+ E L+ + ++R E + + + R++
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL----------EQERREQ 565
Query: 79 ALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARR 138
L RE+E + + EE+R QQ +REQE+R E++ K ++ L+ E RR
Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE----EVERLEQ-----EERR 616
Query: 139 AGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQRE-KVKDEEME 186
L + + EE+E R +++LR+E + +RE ++K EE E
Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665
Score = 49.7 bits (117), Expect = 4e-06
Identities = 44/197 (22%), Positives = 87/197 (44%), Gaps = 28/197 (14%)
Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAV----------- 56
+R R L R+R+ + E L Q E+ + + + D++F +
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711
Query: 57 -EAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115
E +L+ + + + RQE + RQ R+ LEE++L+ ER+ +Q +R+ER R
Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771
Query: 116 KISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRD--REEEENRLREELRQ-- 171
K ++ + R L ++ + D F + +E EE +LR + R
Sbjct: 1772 KFR----------EEEQLRQEREEQQL-RSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820
Query: 172 -EWEAQREKVKDEEMEV 187
WE ++ +++++E +
Sbjct: 1821 YRWEEEQLQLEEQEQRL 1837
Score = 49.3 bits (116), Expect = 5e-06
Identities = 59/246 (23%), Positives = 112/246 (45%), Gaps = 22/246 (8%)
Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDA---VEAELK 61
KG E R + + R+RQ +Q L+ + E+ + ++R D E +L+
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQD--LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLE 1300
Query: 62 SSTVGLVTLNDMKARQEA-LVRE-----RERQLAKRQHLEEQRLQQERQREQEQRRERKR 115
D K+++E L+RE R RQ R+ EE++L QER+ + +R+ER R
Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360
Query: 116 KISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEA 175
K F ++L Q + + + + FL +EE++ R +E +Q +
Sbjct: 1361 K-----FREEELRHQEQGRKFLEEEQRLRRQERERKFL----KEEQQLRCQEREQQLRQD 1411
Query: 176 QREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQL 235
+ K ++EE +++ D +VR+ ++FL++ Q ++ + R EQL
Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE--EQL 1469
Query: 236 MFIKED 241
+ +E+
Sbjct: 1470 LQEREE 1475
Score = 48.9 bits (115), Expect = 6e-06
Identities = 41/172 (23%), Positives = 81/172 (47%), Gaps = 15/172 (8%)
Query: 13 RAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLND 72
R L ++++ +REQ +Q++ E L+ + R + E + + +
Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450
Query: 73 MKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQAD 132
+ R++ L RE E + +H +E+R QQ ++ ++E+RRER K+ +++
Sbjct: 451 QEERRDWLKREEETE----RHEQERRKQQLKRDQEEERRERWLKLE---------EEERR 497
Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184
+ RR L + + R+EEE RL++ LR E + +RE+ + E
Sbjct: 498 EQQERREQQLRREQEERRE--QRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Score = 48.9 bits (115), Expect = 6e-06
Identities = 59/237 (24%), Positives = 101/237 (42%), Gaps = 44/237 (18%)
Query: 3 QYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKS 62
Q + +R R + R+R+ + E L+Q E+ + + + D++F V + +
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 63 STVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSF 122
+ D + + +++ RQ R+ E+++L QER+ +Q R+ER RK
Sbjct: 1595 RKF----MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF----- 1645
Query: 123 ALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDRE--EEENRLREELRQEWEAQR--E 178
L+++ R L DRDR+ EEE L+E Q+ Q
Sbjct: 1646 ----LEEEPQLRRQEREQQLRH----------DRDRKFREEEQLLQEGEEQQLRRQERDR 1691
Query: 179 KVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQL 235
K ++EE ++ RR R RK FL++ Q LR+ LE + EQL
Sbjct: 1692 KFREEEQQL----------RRQERERK------FLQEE-QQLRRQELERKFREEEQL 1731
Score = 45.8 bits (107), Expect = 5e-05
Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 20/170 (11%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKAR-- 76
+K+E QR + E ++R E+ L+ Q ++R AH E E + + R
Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEER--AHRQQQEEEQRRDFTWQWQAEEKSERGR 781
Query: 77 -----QEALVRERERQLA--KRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+ L +RERQL +RQ E++ L +E ++EQ +R+ R+R+ L L++
Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE-----LQFLEE 836
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREK 179
+ RA L + D D++R + + R++ + W+ + E+
Sbjct: 837 EEQLQRRERAQQLQEEED---GLQEDQERRRSQEQRRDQ-KWRWQLEEER 882
Score = 45.8 bits (107), Expect = 5e-05
Identities = 44/127 (34%), Positives = 63/127 (49%), Gaps = 23/127 (18%)
Query: 73 MKARQEALVRE----RERQLAKRQHLEEQRLQQE------RQREQEQRRERKRKISCLSF 122
++ +E L RE R RQ +RQ+ EE++LQQE +RE+ +R+ER+R+
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR-KDK 964
Query: 123 ALDDLDDQ--ADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREE----LRQEWEAQ 176
L ++Q + E RR K + ++EEE LREE RQEWE Q
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEEL-----QQEEEQLLREEREKRRRQEWERQ 1019
Query: 177 REKVKDE 183
K KDE
Sbjct: 1020 YRK-KDE 1025
Score = 45.4 bits (106), Expect = 7e-05
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 23/170 (13%)
Query: 20 KRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEA 79
KRE + E+ E Q ++ + + Q ++R E E + + R++
Sbjct: 459 KREEETERHE---QERRKQQLKRDQEEERRERWLKLEEEERREQ---------QERREQQ 506
Query: 80 LVRERER---QLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEA 136
L RE+E Q KRQ EE+RLQQ + EQ+ RRE++ + L +++ +
Sbjct: 507 LRREQEERREQRLKRQE-EEERLQQRLRSEQQLRREQEERRE----QLLKREEEKRLEQE 561
Query: 137 RRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
RR L + + L R+ E + RL+ R++ E +++K EE+E
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLK---REQEERLEQRLKREEVE 608
Score = 45.1 bits (105), Expect = 9e-05
Identities = 62/246 (25%), Positives = 116/246 (47%), Gaps = 36/246 (14%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
+++ER+ +Q E +Q++ E + + R + E +L+ + + R++
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE-------QEEERREQ 375
Query: 79 ALVRE----RERQLAKRQHLE-EQRLQQERQ--REQEQRRERK-RKISCLSFALDDLDDQ 130
L RE RE+QL + Q L EQ+L++E+Q REQ+ RRE++ R+ L ++ +
Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435
Query: 131 ADAAEARRAGNLGKNPDVDTSFLP---DRDREEEENRLR-------EELRQEW-----EA 175
+ RR L + + +L + +R E+E R + EE R+ W E
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE 495
Query: 176 QREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQL 235
+RE+ + E ++ + +R R + +QQ L+ Q LR++ E R EQL
Sbjct: 496 RREQQERREQQLRREQ-EERREQRLKRQEEEERLQQRLRSE-QQLRREQEERR----EQL 549
Query: 236 MFIKED 241
+ +E+
Sbjct: 550 LKREEE 555
Score = 43.9 bits (102), Expect = 2e-04
Identities = 58/244 (23%), Positives = 109/244 (44%), Gaps = 30/244 (12%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
+++ER+R+ + K + EE +L + +KR + E + +++ +E
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE----------ELQQEEE 1001
Query: 79 ALVRE----RERQLAKRQHLEEQRLQQERQR----EQEQRR--ERKRKISCLSFALDDLD 128
L+RE R RQ +RQ+ ++ LQQE ++ E+E+RR ER+R+ L +
Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR-EEEELQQEE 1060
Query: 129 DQ--ADAAEARRAGNLGKNPDVDTSFLPDRD---REEEENRLREELRQEWEAQREKVKDE 183
+Q + E RR L + + + + REE E R R+E ++ + E ++E
Sbjct: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
Query: 184 EMEVTFSYWDGSGHRRTVRVRKGNTVQ----QFLKKALQGLRKDFLELRSAGVEQLMFIK 239
E + + R+ VQ Q L++ + R+ LE + E+L +
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
Query: 240 EDLI 243
E L+
Sbjct: 1181 EQLL 1184
Score = 43.5 bits (101), Expect = 3e-04
Identities = 42/169 (24%), Positives = 82/169 (48%), Gaps = 22/169 (13%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
++RE+Q E+ E ++R +E + Q+ + + E +L+ + + R++
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRRE---QEERREQQLRRE-------QEEERREQ 362
Query: 79 ALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRERKRKISCLSFALDDLDDQADAAEA 136
L RE+E + ++Q EQ+L++E+Q REQ+ RRE++ L +
Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ---------LRREQQLRREQQL 413
Query: 137 RRAGNLGKNPDVDTSFLPDRDREEEENRLREE-LRQEWEAQREKVKDEE 184
RR L + + +R ++ E RE+ L++E E +R+ +K EE
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462
Score = 42.4 bits (98), Expect = 6e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 24/164 (14%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
++RE+Q Q K R E+ + + + D++F V + +E
Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ----------------ERE 1445
Query: 79 ALVRERERQLAKRQHL---EEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAE 135
E E+QL + +H EE++L QER+ +Q R+ER RK F ++ + +
Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK-----FLEEEQQLRRQERD 1500
Query: 136 ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREK 179
+ ++ + + FL + + + R R+ L++E + +R++
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 50/164 (30%)
Query: 77 QEALVRERERQLAKRQ------HLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQ 130
+E+L+++R ++ +R+ LEE+ Q+ RQ+ QEQ RE L + ++Q
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE-----------LAEGEEQ 154
Query: 131 ADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEVTFS 190
++ E L RDR+ + L + RQEW+ + E+ +EE
Sbjct: 155 SEKQER----------------LEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQ----- 192
Query: 191 YWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQ 234
++ KG+ ++F + Q R++ LELR G E+
Sbjct: 193 ----------LQSCKGHETEEFPDEE-QLRRRELLELRRKGREE 225
Score = 40.4 bits (93), Expect = 0.002
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 42/201 (20%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAV---EAELKSSTVGLVTLNDMKA 75
++RERQ + E L+Q EE +L+ + +KR + E E++ L+ K
Sbjct: 1104 QERERQCREEEELQQE--EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161
Query: 76 RQEALVRE--------RERQLAKRQHLEEQRLQQERQ-REQEQRRERKRKISCLSFALDD 126
R++ L R+ +E + R+ E++R ++ERQ RE+E+ + +KRK D
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK-----QRYRD 1216
Query: 127 LDDQADAA---EARRAGNLGKNP------------DVDTSFLPDRDRE--------EEEN 163
D ++D E + + N ++ S L DR + E++
Sbjct: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 164 RLREELRQEWEAQREKVKDEE 184
R RE+ R+ W+ + +EE
Sbjct: 1277 RDREQERRRWQQRDRHFPEEE 1297
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 19/175 (10%)
Query: 20 KRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEA 79
KRE + E+ E Q +AEE + Q +R + + +L+S + + R++
Sbjct: 673 KREHEEERRE---QELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE 727
Query: 80 LVRERERQLAKRQHLEEQRLQQERQR--EQEQRRERKRKISCLSFALDDLDDQADAAEAR 137
R R+ Q KR+ E + QE +R Q+Q E++R + A + + AR
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR 787
Query: 138 --------RAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184
R + + FLP EEEE R R+E E + + +++EE
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLP----EEEEKEQRRRQRREREKELQFLEEEE 838
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 15/172 (8%)
Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77
L++RER ++ E ++ +SQ +R +E E K TL A Q
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH---TLYAKPALQ 896
Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQ--ADAAE 135
E L +E+QL + + E QR ++E++R QEQ R+ + + L ++Q + E
Sbjct: 897 EQL--RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ-----LQQEEEQLLREERE 949
Query: 136 ARRAGNLGKNPDVDTSFLPDRDR---EEEENRLREELRQEWEAQREKVKDEE 184
RR + D ++ EE E R R+E +++ + E ++EE
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001
Score = 37.7 bits (86), Expect = 0.014
Identities = 33/169 (19%), Positives = 77/169 (45%), Gaps = 10/169 (5%)
Query: 22 ERQREQMEVLKQRIAEETILKSQVDKRF----SAHYDAVEAELKSSTVGLVTLNDMKARQ 77
ER+ + E L+Q +E + + + ++ + E +L+ + + RQ
Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781
Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEAR 137
E ++ Q + R+ EE++L+QER+ +Q + ++R K + ++ Q + E R
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK-----YRWEEEQLQLEEQEQR 1836
Query: 138 RAGNLGKNPDVDTSFLP-DRDREEEENRLREELRQEWEAQREKVKDEEM 185
+ + F ++ R EE+ +EE ++ + + K+++E +
Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885
Score = 35.8 bits (81), Expect = 0.053
Identities = 44/189 (23%), Positives = 82/189 (43%), Gaps = 30/189 (15%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
++R RQR + E Q + EE Q+ +R A +L+ GL + + QE
Sbjct: 818 EQRRRQRREREKELQFLEEE----EQLQRRERAQ------QLQEEEDGLQEDQERRRSQE 867
Query: 79 A---------LVRERERQ---------LAKRQHLEEQRLQQERQR-EQEQRRERKRKISC 119
L ER+R+ L ++ E+Q LQ+E + ++E+R +R+R+
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927
Query: 120 LSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRD-REEEENRLREELRQEWEAQRE 178
+ ++ Q + R + + + + D+ +++EE L EE + +RE
Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987
Query: 179 KVKDEEMEV 187
K EE E+
Sbjct: 988 KKYREEEEL 996
Score = 35.4 bits (80), Expect = 0.070
Identities = 22/96 (22%), Positives = 47/96 (48%), Gaps = 7/96 (7%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
++ +R+ + E L+Q E+ + Q D ++ + ++ E + + +A ++
Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ 1850
Query: 79 ALVRERERQLAKRQHLEEQRLQQERQREQEQRRERK 114
+E+ R+ EEQ L QE ++++ Q RERK
Sbjct: 1851 FATQEKSRR-------EEQELWQEEEQKRRQERERK 1879
Score = 31.2 bits (69), Expect = 1.3
Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 9/115 (7%)
Query: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQA 131
D + +E R R+++ + + L E Q E+Q EQ R+R+R+ L + ++
Sbjct: 126 DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ-RDRQRRDEELWRQRQEWQER- 183
Query: 132 DAAEARRA--GNLGKNPDVDTSFLPDRD--REEEENRLREELRQEWEAQREKVKD 182
E RRA L +T PD + R E LR + R+E + QR + +D
Sbjct: 184 ---EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235
Score = 29.3 bits (64), Expect = 5.0
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 11/104 (10%)
Query: 17 LLKKRERQ--REQMEVLKQRIAEETILKSQVDKRFSAHYDA-VEAELKSSTVGLVTLNDM 73
L ++RE Q R Q K R EE + + ++R D AE + +T
Sbjct: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT-------QE 1855
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKI 117
K+R+E +E + +RQ E++L++E R Q++ +R R++
Sbjct: 1856 KSRREEQELWQEEEQKRRQE-RERKLREEHIRRQQKEEQRHRQV 1898
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 55.8 bits (133), Expect = 5e-08
Identities = 50/184 (27%), Positives = 83/184 (45%), Gaps = 9/184 (4%)
Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSST 64
K RE R ++RER+RE+ ++ E + + DK+ D +A +
Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK- 445
Query: 65 VGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFAL 124
L +EA +ER + R+ + + ++E +RE+E+RRE ++ L L
Sbjct: 446 -----LERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFL 500
Query: 125 DDLDDQADAAEARRAGNLGKN-PDVDTSFLPD-RDREEEENRLREELRQEWEAQREKVKD 182
+D DD D + R L K D + D RDR+ E+ L EE+RQ A+ D
Sbjct: 501 EDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEEL-EEIRQRLLAEGHPDPD 559
Query: 183 EEME 186
E++
Sbjct: 560 AELQ 563
Score = 55.1 bits (131), Expect = 8e-08
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 4/163 (2%)
Query: 25 REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALVRER 84
+E + ++ + ++ ++ K H E + K + + R+ RER
Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER 320
Query: 85 ERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGK 144
ER+ +R+ E+ ++E++RE+E+ R+R R + D D+ + R + +
Sbjct: 321 ERREREREREREREREKEKERERERERDRDRD---RTKERDRDRDRERDRDRDRERSSDR 377
Query: 145 NPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDEEME 186
N D S RDRE E R RE E +E E +RE+ ++ E E
Sbjct: 378 NKDRSRSREKSRDRERERERERERERERERERERERERERERE 420
Score = 47.0 bits (110), Expect = 2e-05
Identities = 53/207 (25%), Positives = 95/207 (45%), Gaps = 35/207 (16%)
Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68
RE R K+RER+RE + R + T + D+ D +SS
Sbjct: 329 REREREREKEKERERERE-----RDRDRDRT---KERDRDRDRERDRDRDRERSSDRNK- 379
Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLD 128
+ ++R+++ RERER+ + + E +R ++ER+RE+E+ RER+R+ D +
Sbjct: 380 --DRSRSREKSRDRERERERERERERERER-ERERERERERERERERERE-KDKKRDREE 435
Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE-AQREKVKDEEMEV 187
D+ DA E R+ +R E+E +E L+ WE +R+K ++ E E
Sbjct: 436 DEEDAYERRKL---------------ERKLREKEAAYQERLK-NWEIRERKKTREYEKEA 479
Query: 188 TFSYWDGSGHRRTVRVRKGNTVQQFLK 214
+ RR ++ +++FL+
Sbjct: 480 -----EREEERRREMAKEAKRLKEFLE 501
Score = 32.3 bits (72), Expect = 0.59
Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 28/94 (29%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
+ R+R++E++E ++QR+ E H D +AEL+ + QE
Sbjct: 534 RDRKREKEELEEIRQRLLAE------------GHPDP-DAELQ------------RMEQE 568
Query: 79 ALVRERERQLAKRQHLEEQRLQQERQREQEQRRE 112
A ER RQ +Q E + ++E+Q ++E+R E
Sbjct: 569 A---ERRRQPQIKQEPESEEEEEEKQEKEEKREE 599
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 52.0 bits (123), Expect = 7e-07
Identities = 58/243 (23%), Positives = 120/243 (49%), Gaps = 41/243 (16%)
Query: 19 KKRERQREQMEVLKQRIAEET----ILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74
++ E ++++E LK+R+ E T ILK++++++ S + +S+ L L +
Sbjct: 182 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS--------DGAASSYQLKQLEEQN 233
Query: 75 AR-QEALVRERERQLAKRQ-HLEEQRLQQERQREQE---QRRER-KRKISCLSFALDDLD 128
AR ++ALVR R+ +++Q H++ Q+L +++ +E E Q+RER + ++S +D+L
Sbjct: 234 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 293
Query: 129 DQADAA-------EARRAGNLGKNPDV--------DTSFLPDRDREEEEN--RLREELRQ 171
+Q DAA E NL V D + + + E +EN ELR+
Sbjct: 294 EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELRE 353
Query: 172 EWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAG 231
+ + +V++ + V + + +++T++ + T LQ + ++ + A
Sbjct: 354 QLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH------LQDVNRELTNQQEAS 407
Query: 232 VEQ 234
VE+
Sbjct: 408 VER 410
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 24/139 (17%)
Query: 50 SAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQ----- 104
S + + A+++ L TL +A +A ++E E+ + + ++E + + + Q
Sbjct: 80 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 139
Query: 105 -REQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN 163
R +E R+E K + ++++ D ADA E + D+E E
Sbjct: 140 RRLKEARKEAKEALEAKERYMEEMADTADAIE-----------------MATLDKEMAEE 182
Query: 164 RLREELRQEWEAQREKVKD 182
R E L+QE EA +E+V +
Sbjct: 183 R-AESLQQEVEALKERVDE 200
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 52.0 bits (123), Expect = 7e-07
Identities = 58/243 (23%), Positives = 120/243 (49%), Gaps = 41/243 (16%)
Query: 19 KKRERQREQMEVLKQRIAEET----ILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74
++ E ++++E LK+R+ E T ILK++++++ S + +S+ L L +
Sbjct: 296 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS--------DGAASSYQLKQLEEQN 347
Query: 75 AR-QEALVRERERQLAKRQ-HLEEQRLQQERQREQE---QRRER-KRKISCLSFALDDLD 128
AR ++ALVR R+ +++Q H++ Q+L +++ +E E Q+RER + ++S +D+L
Sbjct: 348 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 407
Query: 129 DQADAA-------EARRAGNLGKNPDV--------DTSFLPDRDREEEEN--RLREELRQ 171
+Q DAA E NL V D + + + E +EN ELR+
Sbjct: 408 EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELRE 467
Query: 172 EWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAG 231
+ + +V++ + V + + +++T++ + T LQ + ++ + A
Sbjct: 468 QLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH------LQDVNRELTNQQEAS 521
Query: 232 VEQ 234
VE+
Sbjct: 522 VER 524
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 24/139 (17%)
Query: 50 SAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQ----- 104
S + + A+++ L TL +A +A ++E E+ + + ++E + + + Q
Sbjct: 194 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 253
Query: 105 -REQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN 163
R +E R+E K + ++++ D ADA E + D+E E
Sbjct: 254 RRLKEARKEAKEALEAKERYMEEMADTADAIE-----------------MATLDKEMAEE 296
Query: 164 RLREELRQEWEAQREKVKD 182
R E L+QE EA +E+V +
Sbjct: 297 R-AESLQQEVEALKERVDE 314
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 52.0 bits (123), Expect = 7e-07
Identities = 58/243 (23%), Positives = 120/243 (49%), Gaps = 41/243 (16%)
Query: 19 KKRERQREQMEVLKQRIAEET----ILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74
++ E ++++E LK+R+ E T ILK++++++ S + +S+ L L +
Sbjct: 182 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS--------DGAASSYQLKQLEEQN 233
Query: 75 AR-QEALVRERERQLAKRQ-HLEEQRLQQERQREQE---QRRER-KRKISCLSFALDDLD 128
AR ++ALVR R+ +++Q H++ Q+L +++ +E E Q+RER + ++S +D+L
Sbjct: 234 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 293
Query: 129 DQADAA-------EARRAGNLGKNPDV--------DTSFLPDRDREEEEN--RLREELRQ 171
+Q DAA E NL V D + + + E +EN ELR+
Sbjct: 294 EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELRE 353
Query: 172 EWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAG 231
+ + +V++ + V + + +++T++ + T LQ + ++ + A
Sbjct: 354 QLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH------LQDVNRELTNQQEAS 407
Query: 232 VEQ 234
VE+
Sbjct: 408 VER 410
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 24/139 (17%)
Query: 50 SAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQ----- 104
S + + A+++ L TL +A +A ++E E+ + + ++E + + + Q
Sbjct: 80 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 139
Query: 105 -REQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN 163
R +E R+E K + ++++ D ADA E + D+E E
Sbjct: 140 RRLKEARKEAKEALEAKERYMEEMADTADAIE-----------------MATLDKEMAEE 182
Query: 164 RLREELRQEWEAQREKVKD 182
R E L+QE EA +E+V +
Sbjct: 183 R-AESLQQEVEALKERVDE 200
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 52.0 bits (123), Expect = 7e-07
Identities = 58/243 (23%), Positives = 120/243 (49%), Gaps = 41/243 (16%)
Query: 19 KKRERQREQMEVLKQRIAEET----ILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74
++ E ++++E LK+R+ E T ILK++++++ S + +S+ L L +
Sbjct: 316 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS--------DGAASSYQLKQLEEQN 367
Query: 75 AR-QEALVRERERQLAKRQ-HLEEQRLQQERQREQE---QRRER-KRKISCLSFALDDLD 128
AR ++ALVR R+ +++Q H++ Q+L +++ +E E Q+RER + ++S +D+L
Sbjct: 368 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 427
Query: 129 DQADAA-------EARRAGNLGKNPDV--------DTSFLPDRDREEEEN--RLREELRQ 171
+Q DAA E NL V D + + + E +EN ELR+
Sbjct: 428 EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELRE 487
Query: 172 EWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAG 231
+ + +V++ + V + + +++T++ + T LQ + ++ + A
Sbjct: 488 QLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH------LQDVNRELTNQQEAS 541
Query: 232 VEQ 234
VE+
Sbjct: 542 VER 544
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 24/139 (17%)
Query: 50 SAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQ----- 104
S + + A+++ L TL +A +A ++E E+ + + ++E + + + Q
Sbjct: 214 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 273
Query: 105 -REQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN 163
R +E R+E K + ++++ D ADA E + D+E E
Sbjct: 274 RRLKEARKEAKEALEAKERYMEEMADTADAIE-----------------MATLDKEMAEE 316
Query: 164 RLREELRQEWEAQREKVKD 182
R E L+QE EA +E+V +
Sbjct: 317 R-AESLQQEVEALKERVDE 334
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 52.0 bits (123), Expect = 7e-07
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 26/113 (23%)
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133
+ R+ RER+R+ K + LE +R + ER+RE+E+ R+R+R D D D
Sbjct: 687 RERERERERERDREREKERELERERAR-EREREREKERDRER----------DRDRDHDR 735
Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
R +RDRE+E R REE +E E +RE+ ++ E E
Sbjct: 736 ERERER---------------ERDREKEREREREERERERERERERERERERE 773
Score = 46.6 bits (109), Expect = 3e-05
Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 1/117 (0%)
Query: 71 NDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLD-D 129
ND R E R ++ R+ + +ER+R++E+ RER+R+ +L+ +
Sbjct: 651 NDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERE 710
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
+A E R + D D +R+RE E +R +E R+ E +RE+ ++ E E
Sbjct: 711 RAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERE 767
Score = 39.7 bits (91), Expect = 0.004
Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 9/108 (8%)
Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68
RE R ++RER+RE+ E ++R E + + + +R E E +
Sbjct: 677 RERDRERERDRERERERER-ERDREREKERELERERARER--------EREREKERDRER 727
Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRK 116
+ R+ RER+R+ + + EE+ ++ER+RE+E+ RER+R+
Sbjct: 728 DRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775
Score = 38.9 bits (89), Expect = 0.006
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 11/104 (10%)
Query: 84 RERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLG 143
RER + Q E +R++ RRE +R +D +DD+ D R
Sbjct: 635 RERDQRPSSPIRHQGRNDELERDE--RREERR--------VDRVDDRRDERARERDRERE 684
Query: 144 KNPDVDTSFLPDRDRE-EEENRLREELRQEWEAQREKVKDEEME 186
++ + + +RDRE E+E L E +E E +REK +D E +
Sbjct: 685 RDRERERERERERDREREKERELERERAREREREREKERDRERD 728
Score = 34.3 bits (77), Expect = 0.16
Identities = 41/179 (22%), Positives = 75/179 (41%), Gaps = 5/179 (2%)
Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68
RE R K+RER+RE+ E ++R E + + +R + D +
Sbjct: 737 RERERERDREKEREREREERERERERERERERERERERER-ARERDKERERQRDWEDKDK 795
Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLD 128
+D + ++E + +R + + ++R + E Q +R+R+ S S A + D
Sbjct: 796 GRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGD 855
Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEV 187
D+ E R + P S P E+ + R +EE R+ E + + EE E+
Sbjct: 856 DK---NEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKP-ERKESSRRYEEQEL 910
Score = 31.6 bits (70), Expect = 1.0
Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 27/108 (25%)
Query: 81 VRERERQLAKRQHLEEQ-RLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRA 139
V R R L+E+ R + +R+RE+E+R R+R + D AD R
Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQR----------EWDRDADKDWPRNR 1335
Query: 140 GNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDEEME 186
DRDR E R RE + R++ + +RE++ + +E
Sbjct: 1336 ---------------DRDRLRERERERERDKRRDLDRERERLISDSVE 1368
Score = 28.9 bits (63), Expect = 6.5
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 10/102 (9%)
Query: 83 ERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLD--------DQADAA 134
ER Q R+H + + +R RE++ R ER+ + S + D D D+ DA
Sbjct: 404 ERTSQSHDRRHERREDTRGKRDREKDSREEREYE-QDQSSSRDHRDDREPRDGRDRRDAR 462
Query: 135 EARRAGNLGKNPDV-DTSFLPDRDREEEENRLREELRQEWEA 175
+ R L + D+ D+ + D R+ +E+R + R +A
Sbjct: 463 DTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDA 504
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 51.2 bits (121), Expect = 1e-06
Identities = 39/170 (22%), Positives = 83/170 (48%), Gaps = 17/170 (10%)
Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77
+++ +++R + E + E +K++ DK+ + +EAE K++ + R+
Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAA-------QERERR 309
Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDL-DDQADAAEA 136
EA RER R+ KR E QR+++E +R E+R+ K + + + +++ AAE
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369
Query: 137 RRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
R+ + ++ + EE+ R ++ ++ Q K+K E++E
Sbjct: 370 RQRARAEEE---------EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/168 (24%), Positives = 75/168 (44%), Gaps = 16/168 (9%)
Query: 20 KRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEA 79
+ R+R + E L+Q+ EE++ + +A + E K++T T ++ EA
Sbjct: 39 RERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT----TNTQVEGDDEA 94
Query: 80 LVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRA 139
ER LA+R+ ++RLQ+ +R+ +E I+ S +L Q D AE
Sbjct: 95 AFLER---LARREERRQKRLQEALERQ----KEFDPTITDASLSLPSRRMQNDTAENETT 147
Query: 140 GNLGKNPDVDTSFLPDRDREEEENRLREELRQEW-EAQREKVKDEEME 186
K+ + + EE E + + +W +A+ K +D+E E
Sbjct: 148 EKEEKSESRQERY----EIEETETVTKSYQKNDWRDAEENKKEDKEKE 191
Score = 36.6 bits (83), Expect = 0.031
Identities = 35/180 (19%), Positives = 81/180 (45%), Gaps = 12/180 (6%)
Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69
E A ++ +RE+M ++R AEE + +KR + ++ E K +
Sbjct: 299 EKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA---EE 355
Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+K ++ ER+R A+ EE++ + E Q+ +Q E+K + + ++
Sbjct: 356 RQRIKEEEKRAAEERQRARAE----EEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREE--EENRLREELRQEWEA-QREKVKDEEME 186
+ + + + T+ L + E+ + RE+L+++ ++E++KDE+++
Sbjct: 412 KIEGKWVNE--KKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIK 469
Score = 34.3 bits (77), Expect = 0.16
Identities = 36/166 (21%), Positives = 71/166 (42%), Gaps = 19/166 (11%)
Query: 23 RQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALVR 82
+Q E+ E I+ ++ + +R A +EAE +E +
Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAE----------------ERERIKA 282
Query: 83 ERERQLA-KRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGN 141
E+++++A +R +E + ++RE+ + ER+R A ++ + E R A
Sbjct: 283 EQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEE-RQRIKEEEKRAAEE 341
Query: 142 LGKNPDVDTSFLPDRDR-EEEENRLREELRQEWEAQREKVKDEEME 186
+ + + +R R +EEE R EE ++ + EK K EE +
Sbjct: 342 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK 387
Score = 31.6 bits (70), Expect = 1.0
Identities = 27/120 (22%), Positives = 54/120 (45%), Gaps = 15/120 (12%)
Query: 70 LNDMKARQEALVRERERQLAKRQHL--------EEQRLQQERQREQEQRRERKRKISCLS 121
++D + R+E ++RE + + + EE+ ++ R+R +++R +K++ L
Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60
Query: 122 FALDDLDDQA-----DAAEARRAGNLGKNPDVDTSFLPDRDREEE--ENRLREELRQEWE 174
D ++ A D N D + +FL R EE + RL+E L ++ E
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120
Score = 28.9 bits (63), Expect = 6.5
Identities = 44/185 (23%), Positives = 76/185 (41%), Gaps = 46/185 (24%)
Query: 18 LKKRERQREQMEVLKQRIAEETILKSQ-----------VDKRFS-----AHYDAVEAELK 61
+KK + +E+++ R T +KSQ + FS A D EAE
Sbjct: 468 IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGA 527
Query: 62 SSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLS 121
L +++ R+ E +L ++Q +E L+ E E +++RE +RK+
Sbjct: 528 PQVEAGKRLEELRRRRGETESEEFEKLKQKQ--QEAALELE---ELKKKREERRKV---- 578
Query: 122 FALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREEL---RQEWEAQRE 178
+ E RR K + D EEE+ RL+EE+ R E +R+
Sbjct: 579 ---------LEEEEQRR-----KQEEADRKLR----EEEEKRRLKEEIERRRAEAAEKRQ 620
Query: 179 KVKDE 183
K+ ++
Sbjct: 621 KMPED 625
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 50.1 bits (118), Expect = 3e-06
Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 23/138 (16%)
Query: 74 KARQEALVRERERQLAKRQHLEEQR-----LQQERQREQEQRRERKRKISCLSFALDDLD 128
+ R+ RERER+ +++ E +R Q+E +R++E+ RERKRK
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK----------RQ 348
Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME-V 187
+ D R+ G G+ +R+RE E R R+ R+ E +R++ +D + E
Sbjct: 349 TEMDRERNRQTGREGRRQ-------AERERERERERDRQSAREREERERDRDRDRQKERE 401
Query: 188 TFSYWDGSGHRRTVRVRK 205
+ D G R T + R+
Sbjct: 402 RQTEKDRDGQRETEKQRE 419
Score = 49.3 bits (116), Expect = 5e-06
Identities = 56/204 (27%), Positives = 86/204 (42%), Gaps = 28/204 (13%)
Query: 7 TMREAGRAMHLLKKRERQRE-------QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAE 59
T RE R ++RE+Q E + E K+R E + + D+R + +
Sbjct: 228 TDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR-DRRQKERERQTDRK 286
Query: 60 LKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQR---LQQERQREQEQRRERKRK 116
+ T + RQ RERER + + E +R Q+E +R++E+ RERKRK
Sbjct: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346
Query: 117 ISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEE-----NRLREELRQ 171
+D ++ E RR + + + R+REE E +R +E RQ
Sbjct: 347 RQT---EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403
Query: 172 ---------EWEAQREKVKDEEME 186
E E QRE+ KD E E
Sbjct: 404 TEKDRDGQRETEKQREREKDRESE 427
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/183 (25%), Positives = 82/183 (44%), Gaps = 13/183 (7%)
Query: 9 REAGRAMHLLKKRERQRE-QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67
RE R + RERQR+ + E +Q E + + R E E +
Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142
Query: 68 VTLNDMKARQEALVRERERQL-AKRQHLEEQRLQQERQRE--QEQRRERKRKISCLSFAL 124
+ RQ +ERERQ +RQ E+ Q+ER+RE +++RRER+R+
Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ-------- 194
Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDE 183
+ +++ + + R + + +T R + E +R R+ E +E +A+RE+ +
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 184 EME 186
E E
Sbjct: 255 ETE 257
Score = 46.2 bits (108), Expect = 4e-05
Identities = 49/194 (25%), Positives = 76/194 (39%), Gaps = 48/194 (24%)
Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAE-------------ETILKSQVDKRFSAHYDA 55
RE + ++RERQRE+ + R +E ET K Q D+
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 56 VEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115
K + R+ A RE ER + + + R + RQ+E+E++ +RKR
Sbjct: 239 EREREKQAE-----------RERASERETERDKERERERDRDRDRDRRQKERERQTDRKR 287
Query: 116 KISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE---ELRQE 172
+ + D + + R+ +R+RE E NR RE E +E
Sbjct: 288 Q------RRTERDRETERKRERQR---------------ERERERERNRKRERERERERE 326
Query: 173 WEAQREKVKDEEME 186
E QRE +D E E
Sbjct: 327 RERQRETERDREKE 340
Score = 42.0 bits (97), Expect = 7e-04
Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
Query: 76 RQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAE 135
R+ +ERER+ KRQ E ++ER+RE+++ R+R R + + Q D
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 136 AR---RAGNLGKNPDVDTSFLPDRDREEEENRLREELRQ-EWEAQREKVKDEEME 186
R + N K + +T +R R+ + + RE RQ + E +RE+ D E +
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168
Score = 42.0 bits (97), Expect = 7e-04
Identities = 44/164 (26%), Positives = 75/164 (45%), Gaps = 20/164 (12%)
Query: 9 REAGRAMHLLKKRERQRE-QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67
RE R +KRER+RE + E +QR E K + KR E ++ G
Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG- 363
Query: 68 VTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDL 127
R+ RER+RQ A+ +R ++ER R++++++ER+R+ D
Sbjct: 364 ---RRQAERERERERERDRQSAR------EREERERDRDRDRQKERERQTE------KDR 408
Query: 128 DDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQ 171
D Q + + R K+ + + R+RE+++ R R+ RQ
Sbjct: 409 DGQRETEKQRER---EKDRESERGRERGREREKQKGRERDRERQ 449
Score = 38.1 bits (87), Expect = 0.011
Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 12/113 (10%)
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133
+A ++A +RER K + E +R +++ +RE +++RER+R+ D + D
Sbjct: 44 QAHKDADGDDRERNRQKER--ERRREKRQTERETDRKRERRRE--------KDRHRKRDR 93
Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
R+ + K + T DR RE+E NR +E R E E + E+ +D + +
Sbjct: 94 HRERQR-DREKERERQTDRERDRQREKERNRQKERER-ETEREGERGRDRQTD 144
Score = 38.1 bits (87), Expect = 0.011
Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 11/123 (8%)
Query: 72 DMKARQEALV------RERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125
+ + R+E R+RER+ K +H + R +ERQR++E+ RER+
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDR-HRERQRDREKERERQTDRERDRQREK 119
Query: 126 DLDDQAD-AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE---ELRQEWEAQREKVK 181
+ + Q + E R G G++ D +R R+ E+ R R+ E +++ E R+K +
Sbjct: 120 ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKER 179
Query: 182 DEE 184
+ E
Sbjct: 180 ERE 182
Score = 29.6 bits (65), Expect = 3.8
Identities = 24/114 (21%), Positives = 53/114 (46%), Gaps = 9/114 (7%)
Query: 7 TMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVG 66
T RE R ++RER+R++ ++ E + + +R E + + G
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKER--------ERQTEKDRDG 410
Query: 67 LVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120
+ R++ ER R+ + + ++ R +++R+R+ +++ R+RK S L
Sbjct: 411 QRETEKQREREKDRESERGRERGREREKQKGR-ERDRERQTDRQAGRQRKRSTL 463
Score = 28.5 bits (62), Expect = 8.5
Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68
R+ GR +RER+RE+ + E + + R E +
Sbjct: 357 RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK 416
Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115
K R+ RER R+ K++ E R ERQ +++ R+RKR
Sbjct: 417 QREREKDRESERGRERGREREKQKGRERDR---ERQTDRQAGRQRKR 460
>gi|148839339 nexilin (F actin binding protein) [Homo sapiens]
Length = 675
Score = 49.3 bits (116), Expect = 5e-06
Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 16/205 (7%)
Query: 6 GTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65
GT++ M ++ E+++ E K+RI ++ + K ++ + + + +E + T
Sbjct: 100 GTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTE 159
Query: 66 G---------LVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQRE--QEQRRERK 114
L+T+ +K+ + + ++ + +++ E++R++ E + E++R
Sbjct: 160 SASEEGDDSLLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRPSL 219
Query: 115 RKISCLSFALDDLDDQADAAEARRAGNLGKN-PDVDTSFLPDRDREEEE---NRLREELR 170
++ CLS +DD + E+ G L +++ +R ++ EE RL EE R
Sbjct: 220 KEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKR 279
Query: 171 QEWEAQREKV-KDEEMEVTFSYWDG 194
EA+R+ V +DEE + T + G
Sbjct: 280 AFEEARRQMVNEDEENQDTAKIFKG 304
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 9/115 (7%)
Query: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQA 131
D+K + EA+ R RE + +R E+QR +++ RE+E R RK++I + A DD +D +
Sbjct: 30 DVKDKFEAMQRAREERNQRRSRDEKQRRKEQYIREREWNR-RKQEIKEM-LASDDEEDVS 87
Query: 132 DAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
E L T + R E E+ R E+ ++ E ++ +++ + +E
Sbjct: 88 SKVEKAYVPKL-------TGTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLE 135
Score = 34.3 bits (77), Expect = 0.16
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 4/101 (3%)
Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77
L ++E Q++ E +R A + +K + + F D + S +MKAR
Sbjct: 458 LSEKEIQKKIEEERARRRAIDLEIKEREAENFHEEDDVDVRPARKSEAPFTHKVNMKARF 517
Query: 78 EALVRERERQLAKRQHLEEQRL--QQERQREQEQRRERKRK 116
E + + RE + +++ +EEQ+L Q QRE + ++KR+
Sbjct: 518 EQMAKAREEE--EQRRIEEQKLLRMQFEQREIDAALQKKRE 556
Score = 31.2 bits (69), Expect = 1.3
Identities = 34/172 (19%), Positives = 76/172 (44%), Gaps = 10/172 (5%)
Query: 22 ERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALV 81
E +R++ E K++ EE + + +KR A +A + T K + +
Sbjct: 253 ELERQRQENRKKQAEEEARKRLEEEKR--AFEEARRQMVNEDEENQDTAKIFKGYRPGKL 310
Query: 82 RERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGN 141
+ ++ +++ +E+R +E R + + ++ + + +DD + ++
Sbjct: 311 KLSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLT 370
Query: 142 LGKNPDVDTSFLPDRDREEEENRLREELR-------QEWEAQREKVKDEEME 186
GK +++ L + EEE+ R EE + QE+E R+++ +EE E
Sbjct: 371 PGKL-EINFEELLKQKMEEEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEEE 421
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 48.9 bits (115), Expect = 6e-06
Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 38/180 (21%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
K+ E +R++ E L+++ +E IL+ Q ++ + A K ++E
Sbjct: 743 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREEEELARRK--------------QEE 786
Query: 79 ALVRERERQLA-KRQHLEEQRLQQ--------ERQREQEQRRE-----RKRKISCLSFAL 124
AL R+RE+++A +RQ EE+R QQ ER+RE+E+RR+ RK++ +A
Sbjct: 787 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 846
Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184
++ + Q E R ++ R EEE R E++++ E R++ + +E
Sbjct: 847 EEEEAQRRLEENRLR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 898
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Query: 72 DMKARQEALVRERERQLAKRQH--LEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+M+A++E R+R+ +L ++Q L Q+ ++ ++RE+E+ RK++ AL +
Sbjct: 739 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE-----EALRRQRE 793
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
Q A +R + + L +R REEEE R +EEL ++ E + K EE E
Sbjct: 794 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 850
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 20/177 (11%)
Query: 10 EAGRAMHLLKKRERQ----REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65
EA R H ++R+R+ + Q E+++QR ++ L+ ++ + +L SS+
Sbjct: 865 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ--QQQQLAQMKLPSSST 922
Query: 66 GLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125
N + +A + LA+ Q LEE+R ERQ +EQRR+++ + L
Sbjct: 923 WGQQSNTTACQSQATL-----SLAEIQKLEEER---ERQLREEQRRQQRELMKAL----- 969
Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182
Q + GN+ K P T L + +EE +++ +Q+ Q + ++
Sbjct: 970 QQQQQQQQQKLSGWGNVSK-PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1025
Score = 36.6 bits (83), Expect = 0.031
Identities = 35/172 (20%), Positives = 77/172 (44%), Gaps = 16/172 (9%)
Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69
EA R + ++ E +R + E L ++ EE ++ ++ + ++ L
Sbjct: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 871
Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+ + R+E V+ ++ + +RQ +E + ++Q++Q+Q + K S +
Sbjct: 872 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP----SSSTWGQQS 927
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVK 181
A +++ +L + ++ EE E +LREE R++ QRE +K
Sbjct: 928 NTTACQSQATLSLAEIQKLE---------EERERQLREEQRRQ---QRELMK 967
Score = 33.1 bits (74), Expect = 0.35
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 21/180 (11%)
Query: 26 EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLN---------DMKAR 76
+Q + LK RI+++ I+ S V + S EL+ + D
Sbjct: 655 QQFQTLKMRISDQNIIPS-VTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 713
Query: 77 QEALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRE----RKRKISCLSFALDDLDDQ 130
AL + ++ + AK LE++R + E + RE+E+R+ R+++ L ++ +
Sbjct: 714 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 773
Query: 131 ADAAE-ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR----EKVKDEEM 185
+ E ARR + R REEEE + +EE + E +R E+ K EE+
Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 833
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 48.9 bits (115), Expect = 6e-06
Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 38/180 (21%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
K+ E +R++ E L+++ +E IL+ Q ++ + A K ++E
Sbjct: 770 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREEEELARRK--------------QEE 813
Query: 79 ALVRERERQLA-KRQHLEEQRLQQ--------ERQREQEQRRE-----RKRKISCLSFAL 124
AL R+RE+++A +RQ EE+R QQ ER+RE+E+RR+ RK++ +A
Sbjct: 814 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 873
Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184
++ + Q E R ++ R EEE R E++++ E R++ + +E
Sbjct: 874 EEEEAQRRLEENRLR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 925
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Query: 72 DMKARQEALVRERERQLAKRQH--LEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+M+A++E R+R+ +L ++Q L Q+ ++ ++RE+E+ RK++ AL +
Sbjct: 766 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE-----EALRRQRE 820
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
Q A +R + + L +R REEEE R +EEL ++ E + K EE E
Sbjct: 821 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 877
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 20/177 (11%)
Query: 10 EAGRAMHLLKKRERQ----REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65
EA R H ++R+R+ + Q E+++QR ++ L+ ++ + +L SS+
Sbjct: 892 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ--QQQQLAQMKLPSSST 949
Query: 66 GLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125
N + +A + LA+ Q LEE+R ERQ +EQRR+++ + L
Sbjct: 950 WGQQSNTTACQSQATL-----SLAEIQKLEEER---ERQLREEQRRQQRELMKAL----- 996
Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182
Q + GN+ K P T L + +EE +++ +Q+ Q + ++
Sbjct: 997 QQQQQQQQQKLSGWGNVSK-PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1052
Score = 36.6 bits (83), Expect = 0.031
Identities = 35/172 (20%), Positives = 77/172 (44%), Gaps = 16/172 (9%)
Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69
EA R + ++ E +R + E L ++ EE ++ ++ + ++ L
Sbjct: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 898
Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+ + R+E V+ ++ + +RQ +E + ++Q++Q+Q + K S +
Sbjct: 899 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP----SSSTWGQQS 954
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVK 181
A +++ +L + ++ EE E +LREE R++ QRE +K
Sbjct: 955 NTTACQSQATLSLAEIQKLE---------EERERQLREEQRRQ---QRELMK 994
Score = 33.1 bits (74), Expect = 0.35
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 21/180 (11%)
Query: 26 EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLN---------DMKAR 76
+Q + LK RI+++ I+ S V + S EL+ + D
Sbjct: 682 QQFQTLKMRISDQNIIPS-VTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 740
Query: 77 QEALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRE----RKRKISCLSFALDDLDDQ 130
AL + ++ + AK LE++R + E + RE+E+R+ R+++ L ++ +
Sbjct: 741 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 800
Query: 131 ADAAE-ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR----EKVKDEEM 185
+ E ARR + R REEEE + +EE + E +R E+ K EE+
Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 860
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 48.9 bits (115), Expect = 6e-06
Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 38/180 (21%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
K+ E +R++ E L+++ +E IL+ Q ++ + A K ++E
Sbjct: 749 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREEEELARRK--------------QEE 792
Query: 79 ALVRERERQLA-KRQHLEEQRLQQ--------ERQREQEQRRE-----RKRKISCLSFAL 124
AL R+RE+++A +RQ EE+R QQ ER+RE+E+RR+ RK++ +A
Sbjct: 793 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852
Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184
++ + Q E R ++ R EEE R E++++ E R++ + +E
Sbjct: 853 EEEEAQRRLEENRLR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 904
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Query: 72 DMKARQEALVRERERQLAKRQH--LEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+M+A++E R+R+ +L ++Q L Q+ ++ ++RE+E+ RK++ AL +
Sbjct: 745 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE-----EALRRQRE 799
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
Q A +R + + L +R REEEE R +EEL ++ E + K EE E
Sbjct: 800 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 856
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 20/177 (11%)
Query: 10 EAGRAMHLLKKRERQ----REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65
EA R H ++R+R+ + Q E+++QR ++ L+ ++ + +L SS+
Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ--QQQQLAQMKLPSSST 928
Query: 66 GLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125
N + +A + LA+ Q LEE+R ERQ +EQRR+++ + L
Sbjct: 929 WGQQSNTTACQSQATL-----SLAEIQKLEEER---ERQLREEQRRQQRELMKAL----- 975
Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182
Q + GN+ K P T L + +EE +++ +Q+ Q + ++
Sbjct: 976 QQQQQQQQQKLSGWGNVSK-PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1031
Score = 36.6 bits (83), Expect = 0.031
Identities = 35/172 (20%), Positives = 77/172 (44%), Gaps = 16/172 (9%)
Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69
EA R + ++ E +R + E L ++ EE ++ ++ + ++ L
Sbjct: 818 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 877
Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+ + R+E V+ ++ + +RQ +E + ++Q++Q+Q + K S +
Sbjct: 878 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP----SSSTWGQQS 933
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVK 181
A +++ +L + ++ EE E +LREE R++ QRE +K
Sbjct: 934 NTTACQSQATLSLAEIQKLE---------EERERQLREEQRRQ---QRELMK 973
Score = 33.1 bits (74), Expect = 0.35
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 21/180 (11%)
Query: 26 EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLN---------DMKAR 76
+Q + LK RI+++ I+ S V + S EL+ + D
Sbjct: 661 QQFQTLKMRISDQNIIPS-VTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 719
Query: 77 QEALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRE----RKRKISCLSFALDDLDDQ 130
AL + ++ + AK LE++R + E + RE+E+R+ R+++ L ++ +
Sbjct: 720 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 131 ADAAE-ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR----EKVKDEEM 185
+ E ARR + R REEEE + +EE + E +R E+ K EE+
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 48.9 bits (115), Expect = 6e-06
Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 38/180 (21%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
K+ E +R++ E L+++ +E IL+ Q ++ + A K ++E
Sbjct: 749 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREEEELARRK--------------QEE 792
Query: 79 ALVRERERQLA-KRQHLEEQRLQQ--------ERQREQEQRRE-----RKRKISCLSFAL 124
AL R+RE+++A +RQ EE+R QQ ER+RE+E+RR+ RK++ +A
Sbjct: 793 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852
Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184
++ + Q E R ++ R EEE R E++++ E R++ + +E
Sbjct: 853 EEEEAQRRLEENRLR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 904
Score = 47.8 bits (112), Expect = 1e-05
Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
Query: 72 DMKARQEALVRERERQLAKRQH--LEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+M+A++E R+R+ +L ++Q L Q+ ++ ++RE+E+ RK++ AL +
Sbjct: 745 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE-----EALRRQRE 799
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
Q A +R + + L +R REEEE R +EEL ++ E + K EE E
Sbjct: 800 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 856
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 20/177 (11%)
Query: 10 EAGRAMHLLKKRERQ----REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65
EA R H ++R+R+ + Q E+++QR ++ L+ ++ + +L SS+
Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ--QQQQLAQMKLPSSST 928
Query: 66 GLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125
N + +A + LA+ Q LEE+R ERQ +EQRR+++ + L
Sbjct: 929 WGQQSNTTACQSQATL-----SLAEIQKLEEER---ERQLREEQRRQQRELMKAL----- 975
Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182
Q + GN+ K P T L + +EE +++ +Q+ Q + ++
Sbjct: 976 QQQQQQQQQKLSGWGNVSK-PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1031
Score = 36.6 bits (83), Expect = 0.031
Identities = 35/172 (20%), Positives = 77/172 (44%), Gaps = 16/172 (9%)
Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69
EA R + ++ E +R + E L ++ EE ++ ++ + ++ L
Sbjct: 818 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 877
Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129
+ + R+E V+ ++ + +RQ +E + ++Q++Q+Q + K S +
Sbjct: 878 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP----SSSTWGQQS 933
Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVK 181
A +++ +L + ++ EE E +LREE R++ QRE +K
Sbjct: 934 NTTACQSQATLSLAEIQKLE---------EERERQLREEQRRQ---QRELMK 973
Score = 33.1 bits (74), Expect = 0.35
Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 21/180 (11%)
Query: 26 EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLN---------DMKAR 76
+Q + LK RI+++ I+ S V + S EL+ + D
Sbjct: 661 QQFQTLKMRISDQNIIPS-VTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 719
Query: 77 QEALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRE----RKRKISCLSFALDDLDDQ 130
AL + ++ + AK LE++R + E + RE+E+R+ R+++ L ++ +
Sbjct: 720 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 131 ADAAE-ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR----EKVKDEEM 185
+ E ARR + R REEEE + +EE + E +R E+ K EE+
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 48.9 bits (115), Expect = 6e-06
Identities = 43/181 (23%), Positives = 91/181 (50%), Gaps = 15/181 (8%)
Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67
+RE MH ++E+ REQ E +R EE I + + + A E +++ +
Sbjct: 346 IRELEEKMH---EQEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 399
Query: 68 VTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDD 126
+M QE + E+E ++ +++ EE + Q+E+ R QE++ RE+++KI + +
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQE--EEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457
Query: 127 LDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE---AQREKVKDE 183
++ E + GK + + +++EE+ R E++R++ + Q EK++++
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKM---QEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514
Query: 184 E 184
E
Sbjct: 515 E 515
Score = 42.0 bits (97), Expect = 7e-04
Identities = 40/182 (21%), Positives = 86/182 (47%), Gaps = 14/182 (7%)
Query: 18 LKKRERQREQMEV--LKQRIAEETILKSQVDKRFSAHY-----DAVEAELKSSTVGLVTL 70
L + E+ Q+ V LK+++ +L Q + A + +V A+L++
Sbjct: 220 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 279
Query: 71 NDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQ 130
N + +QE + +E ++ +R+ E+ + Q+E+ REQE++ R+ ++ ++
Sbjct: 280 NRLNQQQEEKMWRQEEKIQERE--EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 337
Query: 131 ADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEA----QREKVKDEEM 185
+ + L + ++ +EE ++RE E RQE EA Q EK++++E
Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 186 EV 187
++
Sbjct: 398 KI 399
Score = 41.6 bits (96), Expect = 0.001
Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 25/168 (14%)
Query: 19 KKRERQREQMEVLKQRIAE-ETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77
+K RQ E+++ +++I E E ++ Q +K E E K RQ
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR------------RQ 335
Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEAR 137
E ++ E+E ++ + LEE+ +QE+ REQE++R+ + KI ++ EA+
Sbjct: 336 EEMMWEKEEKI---RELEEKMHEQEKIREQEEKRQEEEKIR--------EQEKRQEQEAK 384
Query: 138 RAGNLGKNPDVDTSFLPDRD-REEEENRLREELRQEWEAQREKVKDEE 184
K + + + +E+E ++ E+ + WE + E + EE
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432
Score = 36.2 bits (82), Expect = 0.041
Identities = 36/191 (18%), Positives = 88/191 (46%), Gaps = 3/191 (1%)
Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKR--FSAHYDAVEAELKS 62
K R+ RA LL +++ Q E + K+ + L++QV++ ++ E ++
Sbjct: 233 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 292
Query: 63 STVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSF 122
+ + QE +RE+E ++ +++ + ++ +++ +R++E E++ KI L
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEK-EEKMRRQEEMMWEKEEKIRELEE 351
Query: 123 ALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182
+ + + + E R+ + + R+EE+ R +EE +E E ++ ++
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411
Query: 183 EEMEVTFSYWD 193
+ E W+
Sbjct: 412 KMGEQEEKMWE 422
Score = 36.2 bits (82), Expect = 0.041
Identities = 36/207 (17%), Positives = 94/207 (45%), Gaps = 28/207 (13%)
Query: 3 QYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAV---EAE 59
Q + +RE + K RQ E++ +++I E+ + + +++ + + E E
Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 60 LKSSTVGLVTLNDMKARQEALVRERERQLAKRQHL---EEQRL----------------Q 100
++ + + QE +RE+E ++ +++ + +E+++ Q
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486
Query: 101 QERQREQEQR-RERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDRE 159
+E+ R QE++ RE+++KI + + ++ E + K + + ++ +E
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE-----EKMQE 541
Query: 160 EEENRLREELRQEWEAQREKVKDEEME 186
+EE R+E + + R + ++E+M+
Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKMQ 568
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 48.5 bits (114), Expect = 8e-06
Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 7/114 (6%)
Query: 76 RQEALVRERERQLAK---RQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQAD 132
RQ +ERERQ + RQ E + ERQRE++++RERKR+ D + + +
Sbjct: 48 RQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107
Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
R G + D +RDRE E R RE RQ QRE+ ++ + E
Sbjct: 108 TDRNRERNRKG-GRERDKQTERERDRERERQRQRERERQR---QRERKRETDRE 157
Score = 39.3 bits (90), Expect = 0.005
Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 8/117 (6%)
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133
+ R+ ERE + +R E+ Q +R++E+E+++ER R+ + + Q +
Sbjct: 23 RQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRER 82
Query: 134 AEAR-RAGNLGKNPDVDTSFLPDRDREEEENRLREELR---QEWEAQREKVKDEEME 186
R R + D D DR+R+ E +R RE R +E + Q E+ +D E E
Sbjct: 83 QRQRERKRQTDRERDKDR----DRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
Score = 38.1 bits (87), Expect = 0.011
Identities = 41/191 (21%), Positives = 80/191 (41%), Gaps = 16/191 (8%)
Query: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60
M + + RE R ++R+RQRE+ +T +++ +R + +
Sbjct: 1 MERQRERKRETDRGKETERERDRQRER--------ENQTERENRHRQRDRHRERDRQTDR 52
Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120
+ + + R+ RE ERQ +RQ E++ Q +R+R++++ RERKR+
Sbjct: 53 EKERERQKERDRQRQRERETERETERQ-RERQRQRERKRQTDRERDKDRDRERKRETDRN 111
Query: 121 -------SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEW 173
D ++ E R + + DRE + REE ++E
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171
Query: 174 EAQREKVKDEE 184
+ +R+K + E+
Sbjct: 172 KKERKKERKEK 182
Score = 33.5 bits (75), Expect = 0.26
Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 16/110 (14%)
Query: 82 RERERQLAKRQHLEEQRLQQERQREQEQR--RERKRKISCLSFALDDLDDQADAAEARRA 139
RER+R+ + + E +R +Q + Q +R R R+R + D Q D + R
Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRD------RHRERDRQTDREKERE- 57
Query: 140 GNLGKNPDVDTSFLPDRDREEEENRLREELRQ---EWEAQREKVKDEEME 186
+ + D +R+ E E R RE RQ + + RE+ KD + E
Sbjct: 58 ----RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRE 103
Score = 29.6 bits (65), Expect = 3.8
Identities = 12/43 (27%), Positives = 27/43 (62%)
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRK 116
+ RQ R+RE +++ E + ++ER++E+++ R+ K+K
Sbjct: 142 RERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKK 184
Score = 28.5 bits (62), Expect = 8.5
Identities = 13/47 (27%), Positives = 31/47 (65%), Gaps = 4/47 (8%)
Query: 74 KARQEALVRER----ERQLAKRQHLEEQRLQQERQREQEQRRERKRK 116
+ R+ RER ER+ K++ +E++ +++ ++++E+RRE K++
Sbjct: 148 RERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/181 (20%), Positives = 92/181 (50%), Gaps = 10/181 (5%)
Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67
+RE + + KK Q EQM+ ++++ E+ + +++ + + + K
Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
Query: 68 VTLNDMKAR---QEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFAL 124
+ D + R Q+ +RE+E ++ +++ + E Q+E+ +E+E+ RER++K+ +
Sbjct: 352 QKMRDQEERMWEQDERLREKEERMREQEKMWE---QEEKMQEEERIREREKKMREEEETM 408
Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPD-RDREEEENRLREELRQEWEAQREKVKDE 183
+ +++ E + + LP+ +++ E+ +++E+ + WE Q EK++D+
Sbjct: 409 REQEEKMQKQEENMWEQ--EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE-QEEKIRDQ 465
Query: 184 E 184
E
Sbjct: 466 E 466
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/186 (21%), Positives = 86/186 (46%), Gaps = 8/186 (4%)
Query: 1 MAQYKGTMREAGRAMHLLKKRERQRE-QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAE 59
+ + +G MRE M +KR R++E ++ ++ + E+ L+ Q ++ E E
Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323
Query: 60 LKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISC 119
K + + RQE + E+E+Q+ R+ ++ R Q+ER EQ++R K +
Sbjct: 324 EK-----MREQEEKMWRQEERLWEQEKQM--REQEQKMRDQEERMWEQDERLREKEERMR 376
Query: 120 LSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREK 179
+ + +++ E R + +T + +++E + E+ +EW+ QR
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Query: 180 VKDEEM 185
+ E++
Sbjct: 437 EQKEKL 442
Score = 46.2 bits (108), Expect = 4e-05
Identities = 51/228 (22%), Positives = 105/228 (46%), Gaps = 30/228 (13%)
Query: 17 LLKKRERQREQMEVLKQ--RIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74
L +K ER REQ ++ +Q ++ EE + Q K + + K
Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD--------------------QEEK 555
Query: 75 ARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDDLDDQADA 133
R+E +RERE+++ R+ E R Q+E+ +EQE++ RE++ K+ + + +++
Sbjct: 556 MREEERMREREKKM--REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613
Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEVTFSYWD 193
E + + + + D + E+E +++E+ + WE Q EK++++E ++
Sbjct: 614 QEEK----MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE-QEEKMREQEEKMREQEEK 668
Query: 194 GSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKED 241
G +R ++ Q K Q + E + G E+ M+ +E+
Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716
Score = 42.4 bits (98), Expect = 6e-04
Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%)
Query: 18 LKKRERQREQMEV--LKQRIAEETILKSQVDKR-FSAHYDAVEAELKSSTVGLVTLNDMK 74
L + E+ Q+ V LK+++ L QV E EL+ + +
Sbjct: 198 LAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 257
Query: 75 ARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAA 134
RQE +RE+E ++ R+ E+ R Q++R REQE+ + K L + ++Q
Sbjct: 258 WRQEERLREQEGKM--REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ 315
Query: 135 EARRAGNLGKNPDVDTSFLPDRDR--------EEEENRLREELRQEWEA-QREKVKDEEM 185
E + K + + +R E+E ++R++ + WE +R + K+E M
Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 375
Query: 186 EVTFSYWD 193
W+
Sbjct: 376 REQEKMWE 383
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/181 (22%), Positives = 88/181 (48%), Gaps = 13/181 (7%)
Query: 19 KKRERQREQM-EVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77
+K RQ E++ E KQ +E ++ Q ++ + E E + + + K ++
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE 390
Query: 78 EALVRERERQLAK-----RQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQAD 132
E +RERE+++ + R+ E+ + Q+E EQE++ +++++ L + ++
Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQ 449
Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEVTFSYW 192
E + K D + + ++ +E ++RE+ Q WE Q EK++D+E ++ W
Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQE-KMREQEDQMWE-QEEKMRDQEQKM----W 503
Query: 193 D 193
D
Sbjct: 504 D 504
Score = 40.4 bits (93), Expect = 0.002
Identities = 44/209 (21%), Positives = 92/209 (44%), Gaps = 26/209 (12%)
Query: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60
M + + TMRE M ++ ++E+ E +QR+ E+ + +K E E
Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHL---EEQRL---------QQERQREQE 108
K + + K ++ +RE+E Q+ +++ +EQ++ Q ER RE+E
Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520
Query: 109 QRRERKRKISCLSFALDD-----------LDDQADAAEARRAGNLGKNPDVDTSFLPDRD 157
+R ++K+ + + D + E R K + + +++
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 158 R--EEEENRLREELRQEWEAQREKVKDEE 184
+E+E ++RE+ + WE Q EK++++E
Sbjct: 581 EKMQEQEEKMREQEEKMWE-QEEKMQEQE 608
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/195 (21%), Positives = 83/195 (42%), Gaps = 22/195 (11%)
Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAE-ETILKSQVDKRFSAHYDAVEAELK----S 62
MRE R KK + E M ++++ E E ++ Q +K + E E K
Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615
Query: 63 STVGLVTLNDMKARQEALVRERERQLAKRQHL-----EEQRLQQERQREQEQR------- 110
+ D QE ++ E+E ++ +++ E+ R Q+E+ REQE++
Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675
Query: 111 -RERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREEL 169
RE++ K+ + + +++ E + G K + + E+E R+R++
Sbjct: 676 MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQK 735
Query: 170 RQEWEAQREKVKDEE 184
E +E++ + E
Sbjct: 736 ----EKMQERLPEHE 746
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/180 (22%), Positives = 86/180 (47%), Gaps = 11/180 (6%)
Query: 17 LLKKRERQREQMEVLKQ--RIAEETILKSQVDKRFSAHYDAV---EAELKSSTVGLVTLN 71
L +K ER REQ ++ +Q ++ EE ++ + +K+ + + E +++ +
Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIRER-EKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 72 DMKARQEALVRERER--QLAKRQHLEEQRLQQERQ-REQEQRRERKRKISCLSFALDDLD 128
+ + +Q+ L ++E+ + K Q EE+ +QE + R+QE+ +++K+ + D
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELR--QEWEAQREKVKDEEME 186
+ E R + + D E+E R+RE+ + Q+ E RE+ K +E E
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQE 546
>gi|109150435 ankyrin repeat and zinc finger domain containing 1
[Homo sapiens]
Length = 726
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 15/85 (17%)
Query: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDDLDDQ 130
+M+ARQ R+RE++ A+RQ E QQ+RQ+EQE+R RE +R+ + LS D + +
Sbjct: 609 EMEARQAT--RKREQKAARRQREE----QQQRQQEQEEREREEQRRFAALS----DREKR 658
Query: 131 ADAAEARRAGNLGKNPDVDTSFLPD 155
A AAE R A LG TS +PD
Sbjct: 659 ALAAERRLAAQLG----APTSPIPD 679
>gi|109150425 ankyrin repeat and zinc finger domain containing 1
[Homo sapiens]
Length = 726
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 15/85 (17%)
Query: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDDLDDQ 130
+M+ARQ R+RE++ A+RQ E QQ+RQ+EQE+R RE +R+ + LS D + +
Sbjct: 609 EMEARQAT--RKREQKAARRQREE----QQQRQQEQEEREREEQRRFAALS----DREKR 658
Query: 131 ADAAEARRAGNLGKNPDVDTSFLPD 155
A AAE R A LG TS +PD
Sbjct: 659 ALAAERRLAAQLG----APTSPIPD 679
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 47.8 bits (112), Expect = 1e-05
Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 18/113 (15%)
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133
K+R+ R R KR+ E+ ++ER +E+++ +ER+R+
Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE----------------- 402
Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
E + GKN D D DR++++E++R RE +E E R+K K++E +
Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDRERER-EKEHEKDRDKEKEKEQD 454
Score = 34.7 bits (78), Expect = 0.12
Identities = 23/103 (22%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 84 RERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLG 143
R+++ R+ ++E+ +E+ RE+E+ RE++R+ D D + + + +
Sbjct: 374 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK-DREKDKEKD 432
Query: 144 KNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
+ + + DRD+E+E+ Q+ E +REK + +E++
Sbjct: 433 REREREKEHEKDRDKEKEK-------EQDKEKEREKDRSKEID 468
Score = 30.0 bits (66), Expect = 2.9
Identities = 21/107 (19%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68
R R + R R++ + +++I E+ +K + ++ E E +
Sbjct: 358 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 417
Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115
K R++ ++RER+ K +H +++ ++E+++++E+ RE+ R
Sbjct: 418 DKEREKDREKDKEKDREREREK-EHEKDRDKEKEKEQDKEKEREKDR 463
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 47.8 bits (112), Expect = 1e-05
Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 18/113 (15%)
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133
K+R+ R R KR+ E+ ++ER +E+++ +ER+R+
Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE----------------- 286
Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
E + GKN D D DR++++E++R RE +E E R+K K++E +
Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDRERER-EKEHEKDRDKEKEKEQD 338
Score = 34.7 bits (78), Expect = 0.12
Identities = 23/103 (22%), Positives = 53/103 (51%), Gaps = 8/103 (7%)
Query: 84 RERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLG 143
R+++ R+ ++E+ +E+ RE+E+ RE++R+ D D + + + +
Sbjct: 258 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK-DREKDKEKD 316
Query: 144 KNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
+ + + DRD+E+E+ Q+ E +REK + +E++
Sbjct: 317 REREREKEHEKDRDKEKEK-------EQDKEKEREKDRSKEID 352
Score = 30.0 bits (66), Expect = 2.9
Identities = 21/107 (19%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68
R R + R R++ + +++I E+ +K + ++ E E +
Sbjct: 242 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 301
Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115
K R++ ++RER+ K +H +++ ++E+++++E+ RE+ R
Sbjct: 302 DKEREKDREKDKEKDREREREK-EHEKDRDKEKEKEQDKEKEREKDR 347
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 47.4 bits (111), Expect = 2e-05
Identities = 49/182 (26%), Positives = 86/182 (47%), Gaps = 21/182 (11%)
Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67
+RE MH ++E+ REQ E +R EE I + + + A E +++ +
Sbjct: 440 IRELEEKMH---EQEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493
Query: 68 VTLNDMKARQEALVRERE--RQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125
+ RQE + E+E R+ KRQ EE Q+E+ REQE+ +K KI
Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI-------H 546
Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE---AQREKVKD 182
+ +++ E + K D + R++EE+ R E++R++ E Q EK+++
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKI---REQEEKVWRQEEKIREQEEKIREQEEKIRE 603
Query: 183 EE 184
+E
Sbjct: 604 QE 605
Score = 43.1 bits (100), Expect = 3e-04
Identities = 41/179 (22%), Positives = 89/179 (49%), Gaps = 19/179 (10%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
++ E+ REQ E +++ +E ++ Q + + E +++ + + RQE
Sbjct: 379 EQEEKIREQEEKIRE---QEEKMRRQEEMMWEK-----EEKMRRQEEMMWEKEEKMRRQE 430
Query: 79 ALVRERE---RQLAKRQH-------LEEQRLQQERQREQEQRRERKRKISCLSFALDDLD 128
++ E+E R+L ++ H EE+R ++E+ REQE+R+E++ K+ + + +
Sbjct: 431 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 490
Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN-RLREELRQEWEAQREKVKDEEME 186
++ E + K + + ++ +E+EE R E++R++ E R+K K E E
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/184 (23%), Positives = 83/184 (45%), Gaps = 15/184 (8%)
Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKR--FSAHYDAVEAELKS 62
K R+ RA LL +++ Q E + K+ + L++QV++ ++ E ++
Sbjct: 306 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 365
Query: 63 STVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSF 122
+ + QE +RE+E ++ R+ E+ R Q+E E+E++ R+ ++
Sbjct: 366 QEEKIQEWEEKIQEQEEKIREQEEKI--REQEEKMRRQEEMMWEKEEKMRRQEEMMW--- 420
Query: 123 ALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182
+ RR + + L ++ E+E+ R +EE RQE E RE+ K
Sbjct: 421 --------EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472
Query: 183 EEME 186
+E E
Sbjct: 473 QEQE 476
Score = 34.3 bits (77), Expect = 0.16
Identities = 34/175 (19%), Positives = 82/175 (46%), Gaps = 24/175 (13%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78
+K RQ E+M +++I E+ + +++ E +++ + +M QE
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ----EEKIREQEEKIREQEEMTQEQE 612
Query: 79 ALVRERERQLAKRQH-LEEQRLQQERQ----REQEQR-RERKRKISCLSFALDDLDDQAD 132
+ E+E ++ +++ ++EQ + RQ REQE++ RE++ KI + + +++
Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 672
Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQ-REKVKDEEME 186
E + + +E+E ++R + + WE + R + ++E+M+
Sbjct: 673 EQEEKMCEQ-------------EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714
Score = 31.2 bits (69), Expect = 1.3
Identities = 40/181 (22%), Positives = 71/181 (39%), Gaps = 27/181 (14%)
Query: 12 GRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDK---RFSAHYDAVEAELKSSTVGLV 68
G A L+ + + L+Q ++ K + D+ + DA+ EL +T+
Sbjct: 219 GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 278
Query: 69 TLNDMKAR-QEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDL 127
L + A+ QE L Q ++ E+ Q +E KRK+ L
Sbjct: 279 ELKEKNAKLQEKL----------------QLVESEKSEIQLNVKELKRKLERAKLLLPQQ 322
Query: 128 DDQADAAEARRAGNLGKN-PDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
QA+A +LGK V + E NRL ++ ++ Q EK+++ E +
Sbjct: 323 QLQAEA------DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 376
Query: 187 V 187
+
Sbjct: 377 I 377
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 47.0 bits (110), Expect = 2e-05
Identities = 61/240 (25%), Positives = 111/240 (46%), Gaps = 36/240 (15%)
Query: 17 LLKKRERQREQMEVLKQ---RIAEETILKSQVDKRFSAHYDAV---EAELKSSTVGLVTL 70
L ++ ER REQ E L++ R+ E+ + ++R + + E L+ L
Sbjct: 201 LREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQ 260
Query: 71 NDMKARQEALVRERERQLAKRQHLEEQRL--QQERQREQEQR--------RERKRKISCL 120
+ QE +RE+E +L H +E+RL Q+ER REQE+R RE++ ++
Sbjct: 261 EERLCEQEERLREQEERL----HEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 316
Query: 121 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN-----RLREELRQEWEA 175
L + +++ E + G +V+ +R +EE+E RL EE+ + E
Sbjct: 317 EERLREQEERLCEQE-KLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQ 375
Query: 176 QREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQL 235
+R + +DE + W + R+R+ +++ L+ + L + E RS G E+L
Sbjct: 376 ERLRQQDERL------WQQETLQELERLRE---LERMLELGWEALYEQRAEPRS-GFEEL 425
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/138 (26%), Positives = 74/138 (53%), Gaps = 8/138 (5%)
Query: 54 DAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHL---EEQRL--QQERQREQE 108
++V +L++ L+ + RQE +RE+E +L +++ +E+RL Q+ER REQE
Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQE 233
Query: 109 QR-RERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDRE-EEENRLR 166
+R RE++ ++ L + +++ E R + + + +R E+E RLR
Sbjct: 234 ERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLR 293
Query: 167 EELRQEWEAQREKVKDEE 184
E+ + E Q E+++++E
Sbjct: 294 EQEERLCE-QEERLREQE 310
Score = 33.9 bits (76), Expect = 0.20
Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 10/124 (8%)
Query: 71 NDMKARQEALVRERERQLAKRQHL------EEQRL--QQERQREQEQR-RERKRKISCLS 121
N ++ E++ R+ + ++ Q L +E+RL Q+ER REQE+R RE++ ++
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQE 226
Query: 122 FALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDRE-EEENRLREELRQEWEAQREKV 180
L + +++ E R + + + +R E+E RLRE+ + E +
Sbjct: 227 ERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLC 286
Query: 181 KDEE 184
+ EE
Sbjct: 287 EQEE 290
Score = 30.8 bits (68), Expect = 1.7
Identities = 41/180 (22%), Positives = 72/180 (40%), Gaps = 17/180 (9%)
Query: 17 LLKKRERQREQMEVL---KQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDM 73
L ++ ER REQ E L ++R+ E+ + ++R + + + + L +
Sbjct: 264 LCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQ 323
Query: 74 KAR---------QEALVRERERQLAKRQHLEEQRLQQERQR-----EQEQRRERKRKISC 119
+ R QE L+ E E+ L + + EEQ ER+R E+ +ER R+
Sbjct: 324 EERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDE 383
Query: 120 LSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREK 179
+ + L + E R LG + P EE N + L+ E + + K
Sbjct: 384 RLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELK 443
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 47.0 bits (110), Expect = 2e-05
Identities = 39/170 (22%), Positives = 84/170 (49%), Gaps = 15/170 (8%)
Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77
LK+ ER R+ ++ ++ + K Q++++F+ + + K+ L + KA++
Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFA------QIDEKTEKAKEERLAEEKAKK 625
Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEAR 137
+A ++ E A+R+ EE R + Q+E+E+RR ++ ++Q +A
Sbjct: 626 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE------LLQKKKEEEQERLRKAA 679
Query: 138 RAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE---AQREKVKDEE 184
A L + + + R++E E RE+ R+E E A++E+ +++E
Sbjct: 680 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE 729
Score = 45.8 bits (107), Expect = 5e-05
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 43/178 (24%)
Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEET--ILKSQVDKRFSAHYDAVEAELKSSTVGL 67
E R + L++ E +R E+L+++ EE + K+ KR + + E
Sbjct: 643 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE-------- 694
Query: 68 VTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQ---RRERKRKISCLSFAL 124
+ R+E RE+ER+ +R+ E Q +QER+REQE+ RE + + L
Sbjct: 695 ------QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 748
Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182
+ L + L ++ ++EE+ RL E RQ E Q +K K+
Sbjct: 749 EQLQRE----------------------LEEKKKKEEQQRLAE--RQLQEEQEKKAKE 782
Score = 41.6 bits (96), Expect = 0.001
Identities = 47/187 (25%), Positives = 90/187 (48%), Gaps = 37/187 (19%)
Query: 24 QREQMEVLKQRIAEETILKSQVDKRFSAHYDA----VEAELKSSTVGLVTLNDMKARQEA 79
QR QM ++ A +++KS + + D VE E + L +++ ++EA
Sbjct: 500 QRNQM-LMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQR-------LENLRRKEEA 551
Query: 80 -LVRERERQLAKRQHLEEQRLQQE---------RQREQEQRRERKRKISCLSFALDDLDD 129
+R ++ + KR+ LEE +L++E R+R ++ + E+K++I +D+ +
Sbjct: 552 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 611
Query: 130 QAD-----AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR-----EK 179
+A +A++ K +V+ R ++EEE R L+QE E +R +K
Sbjct: 612 KAKEERLAEEKAKKKAAAKKMEEVEA-----RRKQEEEARRLRWLQQEEEERRHQELLQK 666
Query: 180 VKDEEME 186
K+EE E
Sbjct: 667 KKEEEQE 673
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 47.0 bits (110), Expect = 2e-05
Identities = 39/170 (22%), Positives = 84/170 (49%), Gaps = 15/170 (8%)
Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77
LK+ ER R+ ++ ++ + K Q++++F+ + + K+ L + KA++
Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFA------QIDEKTEKAKEERLAEEKAKK 621
Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEAR 137
+A ++ E A+R+ EE R + Q+E+E+RR ++ ++Q +A
Sbjct: 622 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE------LLQKKKEEEQERLRKAA 675
Query: 138 RAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE---AQREKVKDEE 184
A L + + + R++E E RE+ R+E E A++E+ +++E
Sbjct: 676 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE 725
Score = 45.8 bits (107), Expect = 5e-05
Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 43/178 (24%)
Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEET--ILKSQVDKRFSAHYDAVEAELKSSTVGL 67
E R + L++ E +R E+L+++ EE + K+ KR + + E
Sbjct: 639 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE-------- 690
Query: 68 VTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQ---RRERKRKISCLSFAL 124
+ R+E RE+ER+ +R+ E Q +QER+REQE+ RE + + L
Sbjct: 691 ------QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744
Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182
+ L + L ++ ++EE+ RL E RQ E Q +K K+
Sbjct: 745 EQLQRE----------------------LEEKKKKEEQQRLAE--RQLQEEQEKKAKE 778
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/178 (25%), Positives = 83/178 (46%), Gaps = 23/178 (12%)
Query: 24 QREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEA-LVR 82
QR QM ++ A +++KS + + D E E + L +++ ++EA +R
Sbjct: 500 QRNQM-LMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR-------LENLRRKEEAEQLR 551
Query: 83 ERERQLAKRQHLEEQRLQ-QERQREQEQRRER-----KRKISCLSFALDDLDDQADAAEA 136
++ + KR+ LEE +L+ +ER R+ Q RER + K + +D++ + A+
Sbjct: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611
Query: 137 RRAGNLGKNPDVDTSFLPD---RDREEEENRLREELRQEWEAQR-----EKVKDEEME 186
R + + R ++EEE R L+QE E +R +K K+EE E
Sbjct: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 669
Score = 28.9 bits (63), Expect = 6.5
Identities = 31/151 (20%), Positives = 62/151 (41%), Gaps = 13/151 (8%)
Query: 82 RERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGN 141
+E+ERQ + +E+ Q RQ+ +E +R R ++ + L A E
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK--REERLRKVLQARERVEQMK 588
Query: 142 LGKNPDVDTSF--LPDRDREEEENRLREE---------LRQEWEAQREKVKDEEMEVTFS 190
K ++ F + ++ + +E RL EE +E EA+R++ ++
Sbjct: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648
Query: 191 YWDGSGHRRTVRVRKGNTVQQFLKKALQGLR 221
+ + + +K Q+ L+KA + R
Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKR 679
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 46.6 bits (109), Expect = 3e-05
Identities = 39/180 (21%), Positives = 82/180 (45%), Gaps = 11/180 (6%)
Query: 7 TMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVG 66
T RE+ R ++RER++ + E K+R E + + K+ + +
Sbjct: 30 TQRESERKK---ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86
Query: 67 LVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDD 126
+ +++ ++RER+ R+ ++++ ++ER+RE +QRRERKRK +
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146
Query: 127 LDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
+ + + R K +R+++ E NR + +E + +RE+ K+ + E
Sbjct: 147 RKREKERGKRERKRKKRKK--------EEREKKRERNRKERKKERERKERRERKKERKKE 198
Score = 34.3 bits (77), Expect = 0.16
Identities = 23/112 (20%), Positives = 52/112 (46%), Gaps = 8/112 (7%)
Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSST 64
K ++ GR KK ++RE+ ++ + K + K + + E K
Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162
Query: 65 VGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRK 116
K + RER R+ K++ ++R +++++R++E+R++++RK
Sbjct: 163 --------RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206
Score = 32.0 bits (71), Expect = 0.77
Identities = 22/102 (21%), Positives = 44/102 (43%), Gaps = 12/102 (11%)
Query: 85 ERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGK 144
E Q+ H+ + Q+E +R++E+R KRK + + R G K
Sbjct: 16 ELQMVSCSHISKPCTQRESERKKERREREKRK------------REREKERKRERGKKEK 63
Query: 145 NPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
+R+R+ +E + + R+E E ++ K + ++ E
Sbjct: 64 KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRE 105
Score = 29.3 bits (64), Expect = 5.0
Identities = 25/138 (18%), Positives = 60/138 (43%), Gaps = 7/138 (5%)
Query: 56 VEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQ-------QERQREQE 108
+ EL+ + ++ + E RER+ KR+ +E++ + + ++RE+
Sbjct: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG 72
Query: 109 QRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREE 168
+ RERKRK ++ + ++ + + +R E EN+ R E
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 169 LRQEWEAQREKVKDEEME 186
+++ ++++ K+ + E
Sbjct: 133 RKRKKRRKKKRRKERKRE 150
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 46.6 bits (109), Expect = 3e-05
Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 24/118 (20%)
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133
+ R+ +RER AK E++ +++RQR++E+ RER R D+
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR-------------DRERE 65
Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQ-----EWEAQREKVKDEEME 186
+ R G + + DRDR+ E R R++ R+ E + +R+K K+ EME
Sbjct: 66 KQTDREGERQRERE------RDRDRQRETERERDKERETDRHTETDRERQKQKEREME 117
Score = 42.4 bits (98), Expect = 6e-04
Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 21/164 (12%)
Query: 5 KGTMREAGRAMHLLKKRERQRE-QMEVLKQRIAE---ETILKSQVDKRFSAHYDAVEAEL 60
K T RE R + R+RQRE + E K+R + ET + Q K
Sbjct: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE 125
Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120
K +G D + RERERQ + + +R ++R RE+E+ R+R+R
Sbjct: 126 KQKEMGRERQTDRETD-----RERERQAERERETGRERKTEDRHRERERERKRER----- 175
Query: 121 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENR 164
+ + + E R ++ + +T DR RE E R
Sbjct: 176 -------ERKRETKERERHTDMERERQRETDRKRDRQRESERER 212
Score = 37.7 bits (86), Expect = 0.014
Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
Query: 90 KRQHLEEQRLQQERQREQEQRRERKR-KISCLSFALDDLDDQADAAEARRAGNLGKNPDV 148
+ H E + + ++R+R +E RER R K S + D Q D R N ++ D
Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRD-----RERNRERDRDR 62
Query: 149 DTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
+ DR+ E + R R+ RQ E +RE+ K+ E +
Sbjct: 63 EREKQTDREGERQRERERDRDRQR-ETERERDKERETD 99
Score = 37.4 bits (85), Expect = 0.018
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 11/115 (9%)
Query: 76 RQEALVRERERQLAKRQHLE---EQRLQQERQREQEQRRER-KRKISCLSFALDDLDDQA 131
RQ RER+++ +H E E++ Q+ER+ E+ + RER K+K D D+
Sbjct: 84 RQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRE 143
Query: 132 DAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186
+A R G+ + DR E R R+ R+ +E+ + +ME
Sbjct: 144 RERQAERERETGRERKTE-------DRHRERERERKRERERKRETKERERHTDME 191
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 46.6 bits (109), Expect = 3e-05
Identities = 37/170 (21%), Positives = 87/170 (51%), Gaps = 21/170 (12%)
Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAE-LKSSTVGLVTLNDMKARQ 77
K+R RQ+ ++ +R + + + ++R A AE LK L L + +
Sbjct: 446 KQRRRQQSEISAAVERARKR---REEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPE 502
Query: 78 EALVRERERQLAKRQHLE---EQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAA 134
E RERE++ + + LE EQ ++ER++++E+++E+++++ +Q
Sbjct: 503 EIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELE---------KEQEKQR 553
Query: 135 EARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQ-EWEAQREKVKDE 183
E + K +++ +++E+E +++E+ ++ E E +REK++++
Sbjct: 554 EMEKERKQEKEKELER----QKEKEKELQKMKEQEKECELEKEREKLEEK 599
Score = 44.3 bits (103), Expect = 1e-04
Identities = 35/113 (30%), Positives = 61/113 (53%), Gaps = 16/113 (14%)
Query: 75 ARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAA 134
A ++ + ++R RQ ++ E+ ++R+ E+E+R E +RK +C L LD+
Sbjct: 439 ADEDEIWKQRRRQQSEISAAVERA--RKRREEEERRMEEQRKAACAE-KLKRLDE----- 490
Query: 135 EARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDEEME 186
+ G L K P + R+RE E+ R RE EL +E E +REK ++++ E
Sbjct: 491 ---KLGILEKQPSPEEI----REREREKEREREKELEKEQEQEREKEREKDRE 536
Score = 42.7 bits (99), Expect = 4e-04
Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 24/115 (20%)
Query: 85 ERQLAKRQHLEEQRLQQE------------RQREQEQRRERKRKISCLSFALDDLDDQAD 132
++Q+A + +QR +Q+ R+ E+E+R E +RK +C L LD+
Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAE-KLKRLDE--- 490
Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDEEME 186
+ G L K P + + +R+RE+E R +E E QE E ++E+ KD E +
Sbjct: 491 -----KLGILEKQPSPEE--IREREREKEREREKELEKEQEQEREKEREKDRERQ 538
Score = 40.0 bits (92), Expect = 0.003
Identities = 27/121 (22%), Positives = 64/121 (52%), Gaps = 8/121 (6%)
Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQR---EQEQRRERKRKISCLSFALDDLDDQ 130
+ RQ++ + + KR+ EE+R++++R+ E+ +R + K I + +++ ++
Sbjct: 448 RRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRER 507
Query: 131 ADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-----ELRQEWEAQREKVKDEEM 185
E R L K + + ++DRE ++ + +E E ++E E +R++ K++E+
Sbjct: 508 EREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKEL 567
Query: 186 E 186
E
Sbjct: 568 E 568
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,656,877
Number of Sequences: 37866
Number of extensions: 524855
Number of successful extensions: 14293
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 297
Number of HSP's successfully gapped in prelim test: 694
Number of HSP's that attempted gapping in prelim test: 5441
Number of HSP's gapped (non-prelim): 4084
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.