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Search of human proteins with 68508965
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68508965 carboxylesterase 1 isoform b precursor [Homo
sapiens]
(567 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens] 1152 0.0
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens] 1147 0.0
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens] 1145 0.0
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens] 473 e-133
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens] 456 e-128
gi|33563374 carboxylesterase 3 [Homo sapiens] 450 e-126
gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens] 429 e-120
gi|115529439 carboxylesterase 8 (putative) [Homo sapiens] 395 e-110
gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens] 365 e-101
gi|51593088 neuroligin 3 [Homo sapiens] 292 6e-79
gi|31317256 X-linked neuroligin 4 [Homo sapiens] 291 8e-79
gi|24308209 X-linked neuroligin 4 [Homo sapiens] 291 8e-79
gi|30840978 neuroligin 2 [Homo sapiens] 291 1e-78
gi|40538788 neuroligin 4, Y-linked [Homo sapiens] 285 1e-76
gi|7662470 neuroligin 1 [Homo sapiens] 284 1e-76
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa... 249 4e-66
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa... 249 4e-66
gi|4557351 butyrylcholinesterase precursor [Homo sapiens] 249 4e-66
gi|148536848 carboxyl ester lipase precursor [Homo sapiens] 234 2e-61
gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens] 195 1e-49
gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens] 194 2e-49
gi|55770862 thyroglobulin [Homo sapiens] 155 9e-38
gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens] 111 2e-24
gi|68299767 arylacetamide deacetylase [Homo sapiens] 42 0.001
gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo sap... 39 0.017
gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo sa... 37 0.037
gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens] 35 0.18
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 33 0.70
gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens] 33 0.91
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 31 2.7
>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
Length = 567
Score = 1152 bits (2979), Expect = 0.0
Identities = 567/567 (100%), Positives = 567/567 (100%)
Query: 1 MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL 60
MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL
Sbjct: 1 MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL 60
Query: 61 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN
Sbjct: 61 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
Query: 121 IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST
Sbjct: 121 IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 301 MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP 360
MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP 360
Query: 361 MQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL 420
MQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL
Sbjct: 361 MQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL 420
Query: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF
Sbjct: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
Query: 481 LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK 540
LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK
Sbjct: 481 LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK 540
Query: 541 DKEVAFWTNLFAKKAVEKPPQTEHIEL 567
DKEVAFWTNLFAKKAVEKPPQTEHIEL
Sbjct: 541 DKEVAFWTNLFAKKAVEKPPQTEHIEL 567
>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
Length = 568
Score = 1147 bits (2967), Expect = 0.0
Identities = 567/568 (99%), Positives = 567/568 (99%), Gaps = 1/568 (0%)
Query: 1 MWLRAFILATLSASAAW-GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 59
MWLRAFILATLSASAAW GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP
Sbjct: 1 MWLRAFILATLSASAAWAGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPP 60
Query: 60 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 119
LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL
Sbjct: 61 LGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYL 120
Query: 120 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 179
NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS
Sbjct: 121 NIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFS 180
Query: 180 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 239
TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL
Sbjct: 181 TGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNL 240
Query: 240 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 299
FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL
Sbjct: 241 FHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTL 300
Query: 300 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 359
KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI
Sbjct: 301 KMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLI 360
Query: 360 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 419
PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD
Sbjct: 361 PMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD 420
Query: 420 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 479
LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP
Sbjct: 421 LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAP 480
Query: 480 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 539
FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL
Sbjct: 481 FLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 540
Query: 540 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 567
KDKEVAFWTNLFAKKAVEKPPQTEHIEL
Sbjct: 541 KDKEVAFWTNLFAKKAVEKPPQTEHIEL 568
>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
Length = 566
Score = 1145 bits (2962), Expect = 0.0
Identities = 566/567 (99%), Positives = 566/567 (99%), Gaps = 1/567 (0%)
Query: 1 MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL 60
MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL
Sbjct: 1 MWLRAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPL 60
Query: 61 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN
Sbjct: 61 GPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
Query: 121 IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST
Sbjct: 121 IYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFST 180
Query: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF
Sbjct: 181 GDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLF 240
Query: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK
Sbjct: 241 HRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLK 300
Query: 301 MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP 360
MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP
Sbjct: 301 MKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIP 360
Query: 361 MQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL 420
M LMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL
Sbjct: 361 M-LMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDL 419
Query: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF
Sbjct: 420 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 479
Query: 481 LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK 540
LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK
Sbjct: 480 LKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLK 539
Query: 541 DKEVAFWTNLFAKKAVEKPPQTEHIEL 567
DKEVAFWTNLFAKKAVEKPPQTEHIEL
Sbjct: 540 DKEVAFWTNLFAKKAVEKPPQTEHIEL 566
>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
Length = 623
Score = 473 bits (1216), Expect = e-133
Identities = 260/557 (46%), Positives = 350/557 (62%), Gaps = 30/557 (5%)
Query: 18 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 77
G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V
Sbjct: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149
Query: 78 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 136
++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM
Sbjct: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207
Query: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA
Sbjct: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267
Query: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 255
ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++
Sbjct: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327
Query: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315
DV ++ +A + C S +V CLR K++EE+L K
Sbjct: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372
Query: 316 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQ 375
++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP + Y ++ ++D+
Sbjct: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYD-TQKEMDR 429
Query: 376 KTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR 435
+ + + L K L+ + E+Y+G D + F +++AD MF +P++ VA
Sbjct: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA- 488
Query: 436 NHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDEL----FSVFGAPFLKEGASEEEIR 491
+ + + AP Y YEFQ++PS+ +++P + DHGDEL S FG ++K +EEE +
Sbjct: 489 HFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHGDELPFVFRSFFGGNYIK--FTEEEEQ 546
Query: 492 LSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLF 551
LS+ +MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW
Sbjct: 547 LSRKMMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKAL 606
Query: 552 AKKAVE-KPPQTEHIEL 567
+K E + P+ H EL
Sbjct: 607 PQKIQELEEPEERHTEL 623
>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
Length = 607
Score = 456 bits (1174), Expect = e-128
Identities = 252/553 (45%), Positives = 340/553 (61%), Gaps = 38/553 (6%)
Query: 18 GHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFV 77
G S+ P+ T G+VLG V ++G V FLGIPFAKPPLGPLRF PP+P E WS V
Sbjct: 90 GQDSASPIRTTHTGQVLGSLVHVKGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGV 149
Query: 78 KNATSYPPMCTQDPKAGQLLSELFTNRKENIPL-KLSEDCLYLNIYTPADLTKKNRLPVM 136
++ T++P MC QD A + SE + P +SEDCLYL+IYTPA + + LPVM
Sbjct: 150 RDGTTHPAMCLQDLTAVE--SEFLSQFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVM 207
Query: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
VWIHGG L+ G AS YDG LAA ENVVVV IQYRLG+ GFFSTGD+H+ GNWG+LDQVA
Sbjct: 208 VWIHGGALVFGMASLYDGSMLAALENVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVA 267
Query: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVA-LTSVL 255
ALRWVQ NIA FGGNP VTIFGESAGG SVS LV+SP+++ LFH AI ESGVA L ++
Sbjct: 268 ALRWVQQNIAHFGGNPDRVTIFGESAGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLI 327
Query: 256 VKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRES 315
DV ++ +A + C S +V CLR K++EE+L K
Sbjct: 328 ASSADV--ISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFK------------- 372
Query: 316 QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQ 375
++ V+DG+ L + P+EL A +F VP +VG+N EFGWLIP + Y ++ ++D+
Sbjct: 373 --MIPGVVDGVFLPRHPQELLASADFQPVPSIVGVNNNEFGWLIPKVMRIYD-TQKEMDR 429
Query: 376 KTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVAR 435
+ + + L K L+ + E+Y+G D + F +++AD MF +P++ VA
Sbjct: 430 EASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDPQTLQAQFQEMMADSMFVIPALQVA- 488
Query: 436 NHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEEIRLSKM 495
+ + + AP Y YEFQ++PS+ +++P + DH +EEE +LS+
Sbjct: 489 HFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADH--------------VKFTEEEEQLSRK 534
Query: 496 VMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKA 555
+MK+WANFARNGNPNGEGLPHWP ++Q+E YLQ+ + LK + FW +K
Sbjct: 535 MMKYWANFARNGNPNGEGLPHWPLFDQEEQYLQLNLQPAVGRALKAHRLQFWKKALPQKI 594
Query: 556 VE-KPPQTEHIEL 567
E + P+ H EL
Sbjct: 595 QELEEPEERHTEL 607
>gi|33563374 carboxylesterase 3 [Homo sapiens]
Length = 571
Score = 450 bits (1157), Expect = e-126
Identities = 249/555 (44%), Positives = 344/555 (61%), Gaps = 38/555 (6%)
Query: 14 SAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEP 73
+ A G + P VDT G+V G+ V ++G + V +FLGIPFA+PPLGP RF+ P PA+P
Sbjct: 24 ATATGPEVAQPEVDTTLGRVRGRQVGVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQP 83
Query: 74 WSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRL 133
W V++A++ PPMC QD ++ S N K+ I +SEDCL LN+Y+PA++ +
Sbjct: 84 WEGVRDASTAPPMCLQDVESMNS-SRFVLNGKQQI-FSVSEDCLVLNVYSPAEVPAGSGR 141
Query: 134 PVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 193
PVMVW+HGG L+ GAA++YDG ALAA+ +VVVVT+QYRLG+ GFFSTGDEH+ GN G LD
Sbjct: 142 PVMVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLD 201
Query: 194 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTS 253
VAALRWVQ+NIA FGG+ VT+FG SAGG +S LVLSP+A LFHRAI++SGV T
Sbjct: 202 VVAALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTP 261
Query: 254 VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 313
++ PLA++IA T C +++ A MV CL+QK EEL+ + K+K
Sbjct: 262 GII-DSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELV-LSKKLK----------- 308
Query: 314 ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373
+ +DG + K+P+EL E+ FH+VP+++G+N EF WLIP G L
Sbjct: 309 --NTIYPLTVDGTVFPKSPKELLKEKPFHSVPFLMGVNNHEFSWLIPR-------GWGLL 359
Query: 374 DQKTAMS---LLWKSYPLVC---IAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFG 427
D MS +L S P++ + E++P ++YLG D K F + + DV
Sbjct: 360 DTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDAQAKCQAFQEFMGDVFIN 419
Query: 428 VPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE---- 483
VP+V +R RD+G+P + YEFQ+RPS + +KP V DHG E VFG PFL +
Sbjct: 420 VPTVSFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHGAEGAFVFGGPFLMDESSR 479
Query: 484 ----GASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKL 539
A+EEE +LS +M W +FAR G+PN + LP WP++NQ E YL+I +A QK
Sbjct: 480 LAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKALPPWPQFNQAEQYLEINPVPRAGQKF 539
Query: 540 KDKEVAFWTNLFAKK 554
++ + FW+ K
Sbjct: 540 REAWMQFWSETLPSK 554
>gi|219521907 carboxylesterase 7 isoform 1 [Homo sapiens]
Length = 575
Score = 429 bits (1104), Expect = e-120
Identities = 242/546 (44%), Positives = 322/546 (58%), Gaps = 33/546 (6%)
Query: 13 ASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 72
A+ G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA
Sbjct: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79
Query: 73 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++
Sbjct: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137
Query: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW
Sbjct: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197
Query: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+
Sbjct: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257
Query: 253 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 309
L K +E + + A G + S ++ CLR K +ELL + K K +
Sbjct: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311
Query: 310 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS 369
V+DG P +L +++ F +P ++G+N E G+L+PM+ LS
Sbjct: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
Query: 370 EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP 429
++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP
Sbjct: 361 GS--NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVP 415
Query: 430 SVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK------E 483
++I AR HRDAGAP Y YEF++RP D KP V DH DE+ VFG FLK E
Sbjct: 416 ALITARYHRDAGAPVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKGDIVMFE 475
Query: 484 GASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKE 543
GA+EEE LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+
Sbjct: 476 GATEEEKLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPR 535
Query: 544 VAFWTN 549
V FWT+
Sbjct: 536 VDFWTS 541
>gi|115529439 carboxylesterase 8 (putative) [Homo sapiens]
Length = 491
Score = 395 bits (1015), Expect = e-110
Identities = 226/565 (40%), Positives = 318/565 (56%), Gaps = 82/565 (14%)
Query: 2 WLRAFILAT-LSASAAWG--HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKP 58
W+ + L L A A G H P VV T +G + GK + + P+ +FLG+PF++P
Sbjct: 3 WILCWSLTLCLMAQTALGALHTKRPQVV-TKYGTLQGKQMHVG--KTPIQVFLGVPFSRP 59
Query: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY 118
PLG LRF PP+P EPW +++AT+YPP C Q+ GQL S + R+ L+ SEDCLY
Sbjct: 60 PLGILRFAPPEPPEPWKGIRDATTYPPGCLQE-SWGQLASMYVSTRERYKWLRFSEDCLY 118
Query: 119 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFF 178
LN+Y PA +LPVMVW GG +VGAAS+Y+G LAA E VV+V +Q+RLGI+GF
Sbjct: 119 LNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFL 178
Query: 179 STGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN 238
ST D H+RGNWG LDQ+AALRWVQ+NIA+FGG+PG+VT+FG+SAG S+S L++SPLA
Sbjct: 179 STDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASG 238
Query: 239 LFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETT 298
LFHRAIS+SG AL + + +K +A+++A AGC ++ ++V+CLR + +++ +
Sbjct: 239 LFHRAISQSGTALFRLFITSNPLK-VAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVS 297
Query: 299 LKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWL 358
KM+FL L+ Q DP E + V+DG+++ P L + +VPY++G+N EF WL
Sbjct: 298 NKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWL 357
Query: 359 IPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTD--DTVKKKDL 416
+P I KE +P E+YL + D ++
Sbjct: 358 LPYN----------------------------ITKEQVPLVVEEYLDNVNEHDWKMLRNR 389
Query: 417 FLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVF 476
+D++ D F ++ A HR
Sbjct: 390 MMDIVQDATFVYATLQTAHYHR-------------------------------------- 411
Query: 477 GAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAA 536
G KE A LS +MK+WANFAR GNPN LP WP YN+ E YLQ+ T+
Sbjct: 412 GLSMGKEKA------LSLQMMKYWANFARTGNPNDGNLPCWPRYNKDEKYLQLDFTTRVG 465
Query: 537 QKLKDKEVAFWTNLFAKKAVEKPPQ 561
KLK+K++AFW +L+ + EK Q
Sbjct: 466 MKLKEKKMAFWMSLYQSQRPEKQRQ 490
>gi|21450749 carboxylesterase 7 isoform 2 [Homo sapiens]
Length = 525
Score = 365 bits (937), Expect = e-101
Identities = 217/540 (40%), Positives = 294/540 (54%), Gaps = 71/540 (13%)
Query: 13 ASAAWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAE 72
A+ G + P +T G + GK V++ G PV +FLG+PFA PPLG LRFT PQPA
Sbjct: 20 AAPTKGPSAEGPQRNTRLGWIQGKQVTVLGSPVPVNVFLGVPFAAPPLGSLRFTNPQPAS 79
Query: 73 PWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
PW ++ ATSYP +C Q+ + LL + + +SEDCLYLNIY PA ++
Sbjct: 80 PWDNLREATSYPNLCLQNSE--WLLLDQHMLKVHYPKFGVSEDCLYLNIYAPAHADTGSK 137
Query: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
LPV+VW GG G+AS +DG ALAA+E+V+VV +QYRLGI+GFF+T D+H+ GNW
Sbjct: 138 LPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGIFGFFTTWDQHAPGNWAFK 197
Query: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
DQVAAL WVQ NI FGG+P SVTIFGESAG SVS L+LSP+AK LFH+AI ESGVA+
Sbjct: 198 DQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSPMAKGLFHKAIMESGVAII 257
Query: 253 SVLVKKGDVKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQ 309
L K +E + + A G + S ++ CLR K +ELL + K K +
Sbjct: 258 PYLEAHDYEK--SEDLQVVAHFCGNNASDSEALLRCLRTKPSKELLTLSQKTKSFT---- 311
Query: 310 GDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLS 369
V+DG P +L +++ F +P ++G+N E G+L+PM+ LS
Sbjct: 312 -----------RVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLLPMKEAPEILS 360
Query: 370 EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVP 429
++ A+ L+ ++ I + + +Y + +D LDL+ DV F VP
Sbjct: 361 GS--NKSLALHLIQN---ILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDVFFVVP 415
Query: 430 SVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKEGASEEE 489
++I AR HR EGA+EEE
Sbjct: 416 ALITARYHR--------------------------------------------EGATEEE 431
Query: 490 IRLSKMVMKFWANFARNGNPNGEGLPHWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTN 549
LS+ +MK+WA FAR GNPNG L WP YN E YLQ+ N Q+LK+ V FWT+
Sbjct: 432 KLLSRKMMKYWATFARTGNPNGNDLSLWPAYNLTEQYLQLDLNMSLGQRLKEPRVDFWTS 491
>gi|51593088 neuroligin 3 [Homo sapiens]
Length = 828
Score = 292 bits (747), Expect = 6e-79
Identities = 199/591 (33%), Positives = 286/591 (48%), Gaps = 89/591 (15%)
Query: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
P V+T GK+ G V L PV +LG+P+A PP+G RF PP+P WS ++NAT
Sbjct: 42 PTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATH 101
Query: 83 YPPMCTQDPKAGQ---LLSELFTNRKENIPLKL---SEDCLYLNIYTPA----------- 125
+PP+C Q+ +L FT + + + +EDCLYLN+Y P
Sbjct: 102 FPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGE 161
Query: 126 -----------DLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174
D+ PVMV+IHGG M G + DG LA++ NV+V+T+ YR+G+
Sbjct: 162 DLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGV 221
Query: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234
GF STGD+ ++GN+G LDQ+ ALRWV +NIA FGG+P +T+FG G VS+L LS
Sbjct: 222 LGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSH 281
Query: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294
++ LF RAI +SG AL+S V VK +A GC + MV CLRQK+ +EL
Sbjct: 282 HSEGLFQRAIIQSGSALSSWAVNYQPVK-YTSLLADKVGCNVLDTVDMVDCLRQKSAKEL 340
Query: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354
+E ++ P G VIDG ++ PE L + F M+G+N+ E
Sbjct: 341 VEQDIQ-----------PARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLGVNQGE 389
Query: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL-- 404
EG +D + +S Y + L PE T K++
Sbjct: 390 ----------GLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYPEGKDTLRETIKFMYT 439
Query: 405 --GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPK 462
D+ ++ + L D + PSV+ A H G+PTY Y F + S MKP
Sbjct: 440 DWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARYGSPTYFYAFYHH--CQSLMKPA 497
Query: 463 TVIGDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH 516
HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN + +P
Sbjct: 498 WSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-KPVPQ 556
Query: 517 ----------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
W +YN ++ YL IG + + +VAFW +L
Sbjct: 557 DTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHL 607
>gi|31317256 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 291 bits (746), Expect = 8e-79
Identities = 200/597 (33%), Positives = 294/597 (49%), Gaps = 77/597 (12%)
Query: 1 MWLRAFILA-TLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKP 58
+WL A + TL S A PVV+T +GK+ G L PV +LG+P+A P
Sbjct: 27 LWLTALAIKFTLIDSQA-----QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASP 81
Query: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSEL----FTNRKENIPLKL-- 112
P G RF PP+P W+ ++N T + +C Q LL ++ FT + + +
Sbjct: 82 PTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQD 141
Query: 113 -SEDCLYLNIYTPA--DLTKKN-RLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI 168
+EDCLYLNIY P D+ +N + PVMV+IHGG M G + DG LA++ NV+V+TI
Sbjct: 142 QNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITI 201
Query: 169 QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVS 228
YRLGI GF STGD+ ++GN+G LDQ+ ALRW+++N+ +FGG+P VTIFG AG VS
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 229 VLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQ 288
+L LS ++ LF +AI +SG AL+S V K +A GC + MV CLR
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRN 320
Query: 289 KTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMV 348
K +EL++ T+ P G VIDG ++ P+ L + F M+
Sbjct: 321 KNYKELIQQTI-----------TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIML 369
Query: 349 GINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL--IPEA------T 400
G+N+ E +G +D + ++ + + L PE T
Sbjct: 370 GVNQGE----------GLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRET 419
Query: 401 EKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFS 456
K++ ++ ++ + L D + P+V A H G+PTY Y F +
Sbjct: 420 IKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQ 477
Query: 457 SDMKPKTVIGDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPN 510
S+MKP HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN
Sbjct: 478 SEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
Query: 511 GEGLPH----------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
+ +P W +YN K+ YL IG + + +VAFW L
Sbjct: 538 -QPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
>gi|24308209 X-linked neuroligin 4 [Homo sapiens]
Length = 816
Score = 291 bits (746), Expect = 8e-79
Identities = 200/597 (33%), Positives = 294/597 (49%), Gaps = 77/597 (12%)
Query: 1 MWLRAFILA-TLSASAAWGHPSSPPVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKP 58
+WL A + TL S A PVV+T +GK+ G L PV +LG+P+A P
Sbjct: 27 LWLTALAIKFTLIDSQA-----QYPVVNTNYGKIRGLRTPLPNEILGPVEQYLGVPYASP 81
Query: 59 PLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQLLSEL----FTNRKENIPLKL-- 112
P G RF PP+P W+ ++N T + +C Q LL ++ FT + + +
Sbjct: 82 PTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLDERSLLHDMLPIWFTANLDTLMTYVQD 141
Query: 113 -SEDCLYLNIYTPA--DLTKKN-RLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI 168
+EDCLYLNIY P D+ +N + PVMV+IHGG M G + DG LA++ NV+V+TI
Sbjct: 142 QNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITI 201
Query: 169 QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVS 228
YRLGI GF STGD+ ++GN+G LDQ+ ALRW+++N+ +FGG+P VTIFG AG VS
Sbjct: 202 NYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVS 261
Query: 229 VLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQ 288
+L LS ++ LF +AI +SG AL+S V K +A GC + MV CLR
Sbjct: 262 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLRN 320
Query: 289 KTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMV 348
K +EL++ T+ P G VIDG ++ P+ L + F M+
Sbjct: 321 KNYKELIQQTI-----------TPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIML 369
Query: 349 GINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKEL--IPEA------T 400
G+N+ E +G +D + ++ + + L PE T
Sbjct: 370 GVNQGE----------GLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRET 419
Query: 401 EKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFS 456
K++ ++ ++ + L D + P+V A H G+PTY Y F +
Sbjct: 420 IKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQ 477
Query: 457 SDMKPKTVIGDHGDELFSVFGAPFLKE------GASEEEIRLSKMVMKFWANFARNGNPN 510
S+MKP HGDE+ VFG P + S+ ++ LS +VM +W NFA+ G+PN
Sbjct: 478 SEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN 537
Query: 511 GEGLPH----------------WPEYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
+ +P W +YN K+ YL IG + + +VAFW L
Sbjct: 538 -QPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
>gi|30840978 neuroligin 2 [Homo sapiens]
Length = 835
Score = 291 bits (744), Expect = 1e-78
Identities = 203/621 (32%), Positives = 298/621 (47%), Gaps = 88/621 (14%)
Query: 1 MWLRAFILATLSASA------AWGHPSSP------------PVVDTVHGKVLGKFVSLEG 42
MWL A L L+ + G P P PVV+T +G+V G L
Sbjct: 1 MWLLALCLVGLAGAQRGGGGPGGGAPGGPGLGLGSLGEERFPVVNTAYGRVRGVRRELNN 60
Query: 43 -FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATSYPPMCTQDPKAGQ---LLS 98
PV FLG+P+A PPLG RF PP+ W V+NAT+ PP C Q+ +L
Sbjct: 61 EILGPVVQFLGVPYATPPLGARRFQPPEAPASWPGVRNATTLPPACPQNLHGALPAIMLP 120
Query: 99 ELFTNRKENIPLKL---SEDCLYLNIYTPAD---LTKKN----------------RLPVM 136
FT+ E + SEDCLYLN+Y P + LTKK + PVM
Sbjct: 121 VWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDEATLNPPDTDIRDPGKKPVM 180
Query: 137 VWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
+++HGG M G + +DG LAA+ NV+V T+ YRLG+ GF STGD+ ++GN+G LDQ+
Sbjct: 181 LFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGLLDQIQ 240
Query: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLV 256
ALRW+ +NIA FGG+P +TIFG AG V++L+LS ++ LF +AI++SG A++S V
Sbjct: 241 ALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSGTAISSWSV 300
Query: 257 KKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQ 316
+K +A GC SA V CLR+K EL++ ++ P
Sbjct: 301 NYQPLK-YTRLLAAKVGCDREDSAEAVECLRRKPSRELVDQDVQ-----------PARYH 348
Query: 317 PLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQK 376
G V+DG ++ PE L + F ++G+N+ E + S
Sbjct: 349 IAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKFVEDSAESEDGVSASAFDF 408
Query: 377 TAMSLLWKSYPLVCIAKELIPEATEKYL----GGTDDTVKKKDLFLDLIADVMFGVPSVI 432
T + + Y K+++ E T K++ D+ ++ L L D + P+V
Sbjct: 409 TVSNFVDNLYGYP-EGKDVLRE-TIKFMYTDWADRDNGEMRRKTLLALFTDHQWVAPAVA 466
Query: 433 VARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLKE------GAS 486
A+ H D +P Y Y F + ++ +P+ HGDEL VFG P + S
Sbjct: 467 TAKLHADYQSPVYFYTFYHH--CQAEGRPEWADAAHGDELPYVFGVPMVGATDLFPCNFS 524
Query: 487 EEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WPEYNQKE-GYLQI 529
+ ++ LS +VM +W NFA+ G+PN + +P W ++N KE YL I
Sbjct: 525 KNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVVWSKFNSKEKQYLHI 583
Query: 530 GANTQAAQKLKDKEVAFWTNL 550
G + + +VAFW L
Sbjct: 584 GLKPRVRDNYRANKVAFWLEL 604
>gi|40538788 neuroligin 4, Y-linked [Homo sapiens]
Length = 816
Score = 285 bits (728), Expect = 1e-76
Identities = 191/573 (33%), Positives = 285/573 (49%), Gaps = 71/573 (12%)
Query: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
PVV+T +GK+ G L PV +LG+P+A PP G RF PP+ W+ ++NAT
Sbjct: 46 PVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQ 105
Query: 83 YPPMCTQDPKAGQLLSEL----FTNRKENIPLKL---SEDCLYLNIYTPA--DLTKKN-R 132
+ +C Q LL ++ FT + + + +EDCLYLNIY P D+ ++N +
Sbjct: 106 FSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSK 165
Query: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
PVMV+IHGG M G + DG LA++ NV+V+TI RLGI GF STGD+ ++GN+G L
Sbjct: 166 KPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINCRLGILGFLSTGDQAAKGNYGLL 225
Query: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALT 252
DQ+ ALRW+++N+ +FGG+P VTIFG AG VS+L LS ++ LF +AI +SG AL+
Sbjct: 226 DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALS 285
Query: 253 SVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDP 312
S V K +A GC + MV CL+ K +EL++ T+ P
Sbjct: 286 SWAVNYQPAK-YTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTI-----------TP 333
Query: 313 RESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQ 372
G VIDG ++ P+ L + F M+G+N+ E +G
Sbjct: 334 ATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE----------GLKFVDGI 383
Query: 373 LDQKTAMSLLWKSYPLVCIAKEL--IPEA------TEKYL----GGTDDTVKKKDLFLDL 420
+D + ++ + + L PE T K++ ++ ++ + L
Sbjct: 384 VDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVAL 443
Query: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
D + P+V A H G+PTY Y F + S+MKP HGDE+ VFG P
Sbjct: 444 FTDHQWVAPAVATADLHAQYGSPTYFYAFYHH--CQSEMKPSWADSAHGDEVPYVFGIPM 501
Query: 481 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 518
+ S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 502 IGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWS 560
Query: 519 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
+YN K+ YL IG + + +VAFW L
Sbjct: 561 KYNPKDQLYLHIGLKPRVRDHYRATKVAFWLEL 593
>gi|7662470 neuroligin 1 [Homo sapiens]
Length = 823
Score = 284 bits (727), Expect = 1e-76
Identities = 192/573 (33%), Positives = 284/573 (49%), Gaps = 62/573 (10%)
Query: 24 PVVDTVHGKVLGKFVSLEG-FAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVKNATS 82
P+V T GK+ G L PV FLG+P+A PP G RF PP+P PWS ++NAT
Sbjct: 53 PLVATNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRNATQ 112
Query: 83 YPPMCTQDPKAGQL----LSELFTNRKENIPLKL---SEDCLYLNIYTPADLTKKNR--- 132
+ P+C Q+ G+L L FTN + + + SEDCLYLNIY P + ++
Sbjct: 113 FAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDSGGP 172
Query: 133 LPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL 192
PVMV+IHGG M G + YDG LA++ NV+V+T+ YRLG+ GF STGD+ ++GN+G L
Sbjct: 173 KPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLL 232
Query: 193 DQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLA---------KNLFHRA 243
D + ALRW +NI FGG+P +T+FG AGG V++L LS + K LF RA
Sbjct: 233 DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLFQRA 292
Query: 244 ISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKF 303
I++SG AL+S V K A +A GC + + +V CL++K +EL++ ++
Sbjct: 293 IAQSGTALSSWAVSFQPAK-YARMLATKVGCNVSDTVELVECLQKKPYKELVDQDIQ--- 348
Query: 304 LSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQL 363
P G VIDG ++ P+ L + F M+G+N+ E G +
Sbjct: 349 --------PARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGE-GLKFVENI 399
Query: 364 MSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATE-KYLGGTD--DTVKKKDLFLDL 420
+ D A+S + K+++ E + Y D + ++ L L
Sbjct: 400 VDSDDGISASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYTDWADRHNPETRRKTLLAL 459
Query: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
D + P+V A H + G+PTY Y F + +D P HGDE+ V G P
Sbjct: 460 FTDHQWVAPAVATADLHSNFGSPTYFYAFYHH--CQTDQVPAWADAAHGDEVPYVLGIPM 517
Query: 481 LKE------GASEEEIRLSKMVMKFWANFARNGNPNGEGLPH----------------WP 518
+ S+ ++ LS +VM +W NFA+ G+PN + +P W
Sbjct: 518 IGPTELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPN-QPVPQDTKFIHTKPNRFEEVAWT 576
Query: 519 EYNQKEG-YLQIGANTQAAQKLKDKEVAFWTNL 550
Y+QK+ YL IG + + + +V W L
Sbjct: 577 RYSQKDQLYLHIGLKPRVKEHYRANKVNLWLEL 609
>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
sapiens]
Length = 614
Score = 249 bits (637), Expect = 4e-66
Identities = 186/560 (33%), Positives = 285/560 (50%), Gaps = 43/560 (7%)
Query: 16 AWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWS 75
A G + +V G++ G + L+ PV+ FLGIPFA+PP+GP RF PP+P +PWS
Sbjct: 31 AEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWS 88
Query: 76 FVKNATSYPPMCTQDPKA---GQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
V +AT++ +C Q G +E++ +E LSEDCLYLN++TP +
Sbjct: 89 GVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRE-----LSEDCLYLNVWTPYP-RPTSP 142
Query: 133 LPVMVWIHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFST-GDEHSRGNW 189
PV+VWI+GGG GA+S YDG L E V+V++ YR+G +GF + G + GN
Sbjct: 143 TPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNV 202
Query: 190 GHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV 249
G LDQ AL+WVQ+N+A+FGG+P SVT+FGESAG SV + +LSP ++ LFHRA+ +SG
Sbjct: 203 GLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262
Query: 250 ALTS-VLVKKGDVKPLAEQIAITAGCKT----TTSAVMVHCLRQKTEEELLETTLKMKFL 304
V G+ + A Q+A GC +V CLR + + L+ +
Sbjct: 263 PNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVL-- 320
Query: 305 SLDLQGDPRES--QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQ 362
P+ES + V+DG L TPE L +FH + +VG+ K E + +
Sbjct: 321 -------PQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYG 373
Query: 363 LMSYPL-SEGQLDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGGTDDTVKKKDLFLDL 420
+ +E + + ++ + P V +A E + +L +D + ++ D+
Sbjct: 374 APGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWL-HPEDPARLREALSDV 432
Query: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
+ D P +A GA Y Y F++R S S P + HG E+ +FG P
Sbjct: 433 VGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLS--WPLWMGVPHGYEIEFIFGIPL 490
Query: 481 --LKEGASEEEIRLSKMVMKFWANFARNGNPN---GEGLPHWPEYNQ-KEGYLQIGAN-T 533
+ +EE+I ++ +M++WANFAR G+PN P WP Y + Y+ +
Sbjct: 491 DPSRNYTAEEKI-FAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPL 549
Query: 534 QAAQKLKDKEVAFWTNLFAK 553
+ + L+ + AFW K
Sbjct: 550 EVRRGLRAQACAFWNRFLPK 569
>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
sapiens]
Length = 617
Score = 249 bits (637), Expect = 4e-66
Identities = 186/560 (33%), Positives = 285/560 (50%), Gaps = 43/560 (7%)
Query: 16 AWGHPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWS 75
A G + +V G++ G + L+ PV+ FLGIPFA+PP+GP RF PP+P +PWS
Sbjct: 31 AEGREDAELLVTVRGGRLRG--IRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWS 88
Query: 76 FVKNATSYPPMCTQDPKA---GQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNR 132
V +AT++ +C Q G +E++ +E LSEDCLYLN++TP +
Sbjct: 89 GVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRE-----LSEDCLYLNVWTPYP-RPTSP 142
Query: 133 LPVMVWIHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFST-GDEHSRGNW 189
PV+VWI+GGG GA+S YDG L E V+V++ YR+G +GF + G + GN
Sbjct: 143 TPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNV 202
Query: 190 GHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV 249
G LDQ AL+WVQ+N+A+FGG+P SVT+FGESAG SV + +LSP ++ LFHRA+ +SG
Sbjct: 203 GLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGA 262
Query: 250 ALTS-VLVKKGDVKPLAEQIAITAGCKT----TTSAVMVHCLRQKTEEELLETTLKMKFL 304
V G+ + A Q+A GC +V CLR + + L+ +
Sbjct: 263 PNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVL-- 320
Query: 305 SLDLQGDPRES--QPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQ 362
P+ES + V+DG L TPE L +FH + +VG+ K E + +
Sbjct: 321 -------PQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYG 373
Query: 363 LMSYPL-SEGQLDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGGTDDTVKKKDLFLDL 420
+ +E + + ++ + P V +A E + +L +D + ++ D+
Sbjct: 374 APGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWL-HPEDPARLREALSDV 432
Query: 421 IADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPF 480
+ D P +A GA Y Y F++R S S P + HG E+ +FG P
Sbjct: 433 VGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLS--WPLWMGVPHGYEIEFIFGIPL 490
Query: 481 --LKEGASEEEIRLSKMVMKFWANFARNGNPN---GEGLPHWPEYNQ-KEGYLQIGAN-T 533
+ +EE+I ++ +M++WANFAR G+PN P WP Y + Y+ +
Sbjct: 491 DPSRNYTAEEKI-FAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPL 549
Query: 534 QAAQKLKDKEVAFWTNLFAK 553
+ + L+ + AFW K
Sbjct: 550 EVRRGLRAQACAFWNRFLPK 569
>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
Length = 602
Score = 249 bits (637), Expect = 4e-66
Identities = 192/553 (34%), Positives = 273/553 (49%), Gaps = 41/553 (7%)
Query: 19 HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 78
H ++ T +GKV G ++L F V FLGIP+A+PPLG LRF PQ WS +
Sbjct: 27 HTEDDIIIATKNGKVRG--MNLTVFGGTVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIW 84
Query: 79 NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 138
NAT Y C Q+ Q + N LSEDCLYLN++ PA K V++W
Sbjct: 85 NATKYANSCCQN--IDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIPAP--KPKNATVLIW 140
Query: 139 IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFST-GDEHSRGNWGHLDQV 195
I+GGG G +S YDG LA E V+VV++ YR+G GF + G+ + GN G DQ
Sbjct: 141 IYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNPEAPGNMGLFDQQ 200
Query: 196 AALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGV-----A 250
AL+WVQ NIA+FGGNP SVT+FGESAG SVS+ +LSP + +LF RAI +SG A
Sbjct: 201 LALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWA 260
Query: 251 LTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQG 310
+TS+ + LA+ GC ++ CLR K +E+L L F+ G
Sbjct: 261 VTSLYEARNRTLNLAK----LTGCSRENETEIIKCLRNKDPQEIL---LNEAFVV--PYG 311
Query: 311 DPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSE 370
P G +DG L P+ L F +VG+NK E + +
Sbjct: 312 TPLSVN--FGPTVDGDFLTDMPDILLELGQFKKTQILVGVNKDEGTAFLVYGAPGFSKDN 369
Query: 371 GQ-LDQKTAMSLLWKSYPLVC-IAKELIPEATEKYLGGTDDTVKK--KDLFLDLIADVMF 426
+ +K L +P V KE I Y DD + ++ D++ D F
Sbjct: 370 NSIITRKEFQEGLKIFFPGVSEFGKESI---LFHYTDWVDDQRPENYREALGDVVGDYNF 426
Query: 427 GVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMK-PKTVIGDHGDELFSVFGAPF-LKEG 484
P++ + + G + Y F++R SS + P+ + HG E+ VFG P ++
Sbjct: 427 ICPALEFTKKFSEWGNNAFFYYFEHR---SSKLPWPEWMGVMHGYEIEFVFGLPLERRDN 483
Query: 485 ASEEEIRLSKMVMKFWANFARNGNPN--GEGLPHWPEYNQKE-GYLQIGA-NTQAAQKLK 540
++ E LS+ ++K WANFA+ GNPN WP + E YL + +T+ KL+
Sbjct: 484 YTKAEEILSRSIVKRWANFAKYGNPNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTKLR 543
Query: 541 DKEVAFWTNLFAK 553
++ FWT+ F K
Sbjct: 544 AQQCRFWTSFFPK 556
>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
Length = 756
Score = 234 bits (596), Expect = 2e-61
Identities = 189/571 (33%), Positives = 268/571 (46%), Gaps = 63/571 (11%)
Query: 8 LATLSASAAWGHPSSPPV--VDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRF 65
L L + W S+ + V T G V G L V IF GIPFA P
Sbjct: 9 LVVLGLTCCWAVASAAKLGAVYTEGGFVEGVNKKLGLLGDSVDIFKGIPFAAPTKA---L 65
Query: 66 TPPQPAEPWSFVKNATSYPPMC-----TQDPKAGQLLSELFTNRKENIPLKLSEDCLYLN 120
PQP W A ++ C TQD G EDCLYLN
Sbjct: 66 ENPQPHPGWQGTLKAKNFKKRCLQATITQDSTYGD------------------EDCLYLN 107
Query: 121 IYTPADLTKKNR-LPVMVWIHGGGLMVGAAS--------TYDGLALAAHENVVVVTIQYR 171
I+ P + +R LPVM+WI+GG ++G+ YDG +A NV+VVT YR
Sbjct: 108 IWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVTFNYR 167
Query: 172 LGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLV 231
+G GF STGD + GN+G DQ A+ WV+ NIA+FGG+P ++T+FGESAGG SVS+
Sbjct: 168 VGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQT 227
Query: 232 LSPLAKNLFHRAISESGVALTSVLVKKGDVKPL--AEQIAITAGCKTTTSAVMVHCLRQK 289
LSP K L RAIS+SGVAL+ +++K PL A+++A GC +A M CL+
Sbjct: 228 LSPYNKGLIRRAISQSGVALSPWVIQK---NPLFWAKKVAEKVGCPVGDAARMAQCLK-V 283
Query: 290 TEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG 349
T+ L K+ L+ P VIDG + P L A N + Y+ G
Sbjct: 284 TDPRALTLAYKVPLAGLEY---PMLHYVGFVPVIDGDFIPADPINLYA--NAADIDYIAG 338
Query: 350 INKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCI--AKELIPEATEKYLGGT 407
N + + + + ++ ++ L+ + + AK TE +
Sbjct: 339 TNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYTESWAQDP 398
Query: 408 DDTVKKKDLFLDLIADVMFGVPSVIVARNHR--DAGAPTYMYEFQYRPSFSSDMKPKTVI 465
KKK + +D DV+F VP+ I HR A TY Y F + PS + PK V
Sbjct: 399 SQENKKKTV-VDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSH-PS-RMPVYPKWVG 455
Query: 466 GDHGDELFSVFGAPF-LKEGASEEEIRLSKMVMKFWANFARNGNPN--GEGLP-HWPEY- 520
DH D++ VFG PF G ++ +SK ++ +W NFA+ G+PN +P HW Y
Sbjct: 456 ADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPNMGDSAVPTHWEPYT 515
Query: 521 NQKEGYLQIG---ANTQAAQKLKDKEVAFWT 548
+ GYL+I ++ + L+ + +WT
Sbjct: 516 TENSGYLEITKKMGSSSMKRSLRTNFLRYWT 546
>gi|169216018 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 195 bits (495), Expect = 1e-49
Identities = 116/301 (38%), Positives = 170/301 (56%), Gaps = 25/301 (8%)
Query: 141 GGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRW 200
GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQVAAL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 201 VQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 260
VQ NI FGG+P SVTIFGES G SVS L+LSP+A+ LFH+A+ ESGVA+ +L K
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLMLSPMAEGLFHKAVMESGVAI--ILYLKAH 137
Query: 261 VKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQP 317
+E + + A G + S + CLR K+ +ELL + K K +
Sbjct: 138 DYEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFT------------ 185
Query: 318 LLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKT 377
V+DG P +L +++ F +P ++G+N E G+ +PM+ LS ++
Sbjct: 186 ---QVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGS--NKSL 240
Query: 378 AMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNH 437
A+ L + ++ I + +Y + +D LDL+ DV F +P +I AR H
Sbjct: 241 ALCL---TQNILHILPNYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITARYH 297
Query: 438 R 438
R
Sbjct: 298 R 298
>gi|169215613 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 327
Score = 194 bits (493), Expect = 2e-49
Identities = 115/301 (38%), Positives = 170/301 (56%), Gaps = 25/301 (8%)
Query: 141 GGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRW 200
GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQVAAL W
Sbjct: 20 GGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQVAALSW 79
Query: 201 VQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGD 260
VQ NI FGG+P SVTIFGES G SVS L+LSP+A+ LFH+A+ ESGVA+ +L K
Sbjct: 80 VQKNIEFFGGDPSSVTIFGESVGAISVSSLILSPMAEGLFHKAVMESGVAI--ILYLKAH 137
Query: 261 VKPLAEQIAITA---GCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQP 317
+E + + A G + S + CLR K+ +ELL + K K +
Sbjct: 138 DYEKSEDLQVVAQFCGYNASDSEAPLRCLRTKSSKELLTLSQKTKAFT------------ 185
Query: 318 LLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKT 377
V+DG P +L +++ F +P ++G+N E G+ +PM+ LS ++
Sbjct: 186 ---QVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNPECGFPLPMKEAPEILSGS--NKSL 240
Query: 378 AMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLDLIADVMFGVPSVIVARNH 437
A+ L + ++ I + +Y + +D LDL+ DV F +P +I A+ H
Sbjct: 241 ALCL---TQNILHILPNYLHLVAGEYFHDKHSLTEIRDSLLDLLGDVFFVIPKLITAQYH 297
Query: 438 R 438
R
Sbjct: 298 R 298
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 155 bits (392), Expect = 9e-38
Identities = 157/554 (28%), Positives = 241/554 (43%), Gaps = 57/554 (10%)
Query: 21 SSPPVVDTVHGKVLGKFVSLEGFA--QPVAIFLGIPFAKPPLGPLRFTPPQPAEPWSFVK 78
S P V + HG++LG+ +++ + V FLG+P+A PPL RF P+P W+
Sbjct: 2197 SVPSVPISTHGRLLGRSQAIQVGTSWKQVDQFLGVPYAAPPLAERRFQAPEPLN-WTGSW 2255
Query: 79 NATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLYLNIYTPADLTKKNRLPVMVW 138
+A+ C Q R P +SEDCLYLN++ P ++ V+V+
Sbjct: 2256 DASKPRASCWQPG-----------TRTSTSP-GVSEDCLYLNVFIPQNVAPN--ASVLVF 2301
Query: 139 IHGGGLMVGAAS--TYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVA 196
H + DG LAA N++VVT YR+G++GF S+G GNWG LDQVA
Sbjct: 2302 FHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLSSGSGEVSGNWGLLDQVA 2361
Query: 197 ALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSPLAKN--LFHRAISESGVALT-S 253
AL WVQ +I FGG+P V++ + G + S+ +L+ A N LF RA+ G AL+ +
Sbjct: 2362 ALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNSQLFRRAVLMGGSALSPA 2421
Query: 254 VLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPR 313
++ + A +A C ++S +V CLRQK L + K+ +S
Sbjct: 2422 AVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLNDAQTKLLAVSGPFH---- 2477
Query: 314 ESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQL 373
G VIDG L + P + V ++G ++ + + + S G+
Sbjct: 2478 ----YWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVKQFEESRGRT 2533
Query: 374 DQKTAM-SLLWKSYPLVCIAKELIPEATEKYL--GGTDDTVKKKDLFLDLIADVMFGVPS 430
KTA L S + AT Y TDD + D P
Sbjct: 2534 SSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENATRDYFIICPI 2593
Query: 431 VIVARN-HRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFSVFGAPFLK--EGA-S 486
+ +A + A +MY S + D F++ G PF EG S
Sbjct: 2594 IDMASAWAKRARGNVFMYHAPENYGHGS-------LELLADVQFAL-GLPFYPAYEGQFS 2645
Query: 487 EEEIRLSKMVMKFWANFARNGNPN-----GEGLP----HWPEYNQK---EGYLQIGANTQ 534
EE LS +M+++++F R+GNPN +P WP++ + E Y +
Sbjct: 2646 LEEKSLSLKIMQYFSHFIRSGNPNYPYEFSRKVPTFATPWPDFVPRAGGENYKEFSELLP 2705
Query: 535 AAQKLKDKEVAFWT 548
Q LK + +FW+
Sbjct: 2706 NRQGLKKADCSFWS 2719
>gi|239752162 PREDICTED: similar to hCG40360 [Homo sapiens]
Length = 131
Score = 111 bits (277), Expect = 2e-24
Identities = 51/90 (56%), Positives = 67/90 (74%)
Query: 135 VMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQ 194
V++W GG G+AS +DG +LAA+E+++VV +QYRLGI+GFF+T D+H+ GNW DQ
Sbjct: 20 VLLWFPGGAFETGSASIFDGSSLAAYEDMLVVIVQYRLGIFGFFTTWDQHAPGNWAFKDQ 79
Query: 195 VAALRWVQDNIASFGGNPGSVTIFGESAGG 224
VAAL WVQ NI FGG+P SVTIF + G
Sbjct: 80 VAALSWVQKNIEFFGGDPSSVTIFDAVSHG 109
>gi|68299767 arylacetamide deacetylase [Homo sapiens]
Length = 399
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 16/114 (14%)
Query: 117 LYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAA--STYDGLA--LAAHENVVVVTIQYRL 172
+ + +Y P ++ R + +IHGGG VG+A S YD L+ A + VVV+ YRL
Sbjct: 89 ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147
Query: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGG 224
F E D ALRW + +A +G NP + I G+SAGG
Sbjct: 148 APKYHFPIQFE---------DVYNALRWFLRKKVLAKYGVNPERIGISGDSAGG 192
>gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo
sapiens]
Length = 440
Score = 38.5 bits (88), Expect = 0.017
Identities = 32/101 (31%), Positives = 50/101 (49%), Gaps = 15/101 (14%)
Query: 136 MVWIHGGGLMVGAAST--YDGL--ALAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGH 191
+V+IHGGG + +A YD L A+A N V+V+I+YRL +F
Sbjct: 141 VVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIH-------- 192
Query: 192 LDQVAALRWV--QDNIASFGGNPGSVTIFGESAGGESVSVL 230
D V A ++ + + + +PG + I G+SAGG + L
Sbjct: 193 -DVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAAL 232
>gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo
sapiens]
Length = 448
Score = 37.4 bits (85), Expect = 0.037
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 23/109 (21%)
Query: 136 MVWIHGGGLMVGAAST----------YDGL--ALAAHENVVVVTIQYRLGIWGFFSTGDE 183
+V+IHGGG + +AS YD L A+A N V+V+I+YRL +F
Sbjct: 141 VVYIHGGGWALASASASWSPSDEIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIH 200
Query: 184 HSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGGESVSVL 230
D V A ++ + + + +PG + I G+SAGG + L
Sbjct: 201 ---------DVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAAL 240
>gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens]
Length = 407
Score = 35.0 bits (79), Expect = 0.18
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 11/97 (11%)
Query: 136 MVWIHGGGLMVGAASTYDGLA--LAAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLD 193
+++ HGG + G+ Y GL LA V++ I YR D HS + D
Sbjct: 115 IIFYHGGATVFGSLDCYHGLCNYLARETESVLLMIGYR-------KLPDHHSPALFQ--D 165
Query: 194 QVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVL 230
+ A + ++G +P V + GES GG +V+ +
Sbjct: 166 CMNASIHFLKALETYGVDPSRVVVCGESVGGAAVAAI 202
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 33.1 bits (74), Expect = 0.70
Identities = 14/25 (56%), Positives = 16/25 (64%)
Query: 46 PVAIFLGIPFAKPPLGPLRFTPPQP 70
P +F G PF +PPLGPL PP P
Sbjct: 275 PPVLFPGQPFGQPPLGPLPPGPPPP 299
>gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]
Length = 401
Score = 32.7 bits (73), Expect = 0.91
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 16/112 (14%)
Query: 119 LNIYTPADLTKKNRLPVMVWIHGGGLMVGAAS--TYDGLA--LAAHENVVVVTIQYRLGI 174
+ +Y P ++ R V ++ HGGG G++ +D L A + VVV + YRL
Sbjct: 91 VRLYLPKRKSETRRRAV-IYFHGGGFCFGSSKQRAFDFLNRWTANTLDAVVVGVDYRLAP 149
Query: 175 WGFFSTGDEHSRGNWGHLDQVAALRW--VQDNIASFGGNPGSVTIFGESAGG 224
F E D +AA+++ ++ + +G +P + I G+S+GG
Sbjct: 150 QHHFPAQFE---------DGLAAVKFFLLEKILTKYGVDPTRICIAGDSSGG 192
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 31.2 bits (69), Expect = 2.7
Identities = 22/68 (32%), Positives = 25/68 (36%), Gaps = 9/68 (13%)
Query: 4 RAFILATLSASAAWGHPSSPPVVDTVHGKVLGKFVSL---------EGFAQPVAIFLGIP 54
R I A HP PPV T+ G LG SL + QPV + G P
Sbjct: 495 RVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTP 554
Query: 55 FAKPPLGP 62
PP P
Sbjct: 555 GMAPPPAP 562
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,928,624
Number of Sequences: 37866
Number of extensions: 1081121
Number of successful extensions: 2783
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2639
Number of HSP's gapped (non-prelim): 46
length of query: 567
length of database: 18,247,518
effective HSP length: 108
effective length of query: 459
effective length of database: 14,157,990
effective search space: 6498517410
effective search space used: 6498517410
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.