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Search of human proteins with 55956888
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55956888 kelch/ankyrin repeat containing cyclin A1
interacting protein isoform a [Homo sapiens]
(349 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55956888 kelch/ankyrin repeat containing cyclin A1 interactin... 746 0.0
gi|55956890 kelch/ankyrin repeat containing cyclin A1 interactin... 489 e-138
gi|55956892 kelch/ankyrin repeat containing cyclin A1 interactin... 241 7e-64
gi|7657301 kelch domain containing 2 [Homo sapiens] 44 3e-04
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 43 4e-04
gi|55925604 kelch-like 18 [Homo sapiens] 43 5e-04
gi|25188199 leucine carboxyl methyltransferase 2 [Homo sapiens] 40 0.004
gi|24475847 influenza virus NS1A binding protein [Homo sapiens] 39 0.007
gi|17017980 kelch-like 4 isoform 2 [Homo sapiens] 36 0.045
gi|17017982 kelch-like 4 isoform 1 [Homo sapiens] 36 0.045
gi|38194229 kelch-like 17 [Homo sapiens] 36 0.045
gi|148664209 kelch-like 10 [Homo sapiens] 36 0.059
gi|88196794 kelch-like 35 [Homo sapiens] 36 0.059
gi|16945972 kelch domain containing 3 [Homo sapiens] 36 0.059
gi|34101268 kelch-like 8 [Homo sapiens] 35 0.100
gi|41393547 neuroblastoma-amplified protein [Homo sapiens] 35 0.13
gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens] 33 0.29
gi|31881798 muskelin 1, intracellular mediator containing kelch ... 33 0.50
gi|223890246 muskelin 1, intracellular mediator containing kelch... 33 0.50
gi|26190616 kelch domain containing 1 [Homo sapiens] 33 0.50
gi|46410931 attractin-like 1 [Homo sapiens] 32 0.65
gi|40018614 DRE1 protein [Homo sapiens] 32 0.85
gi|21450863 attractin isoform 2 [Homo sapiens] 32 1.1
gi|21450861 attractin isoform 1 [Homo sapiens] 32 1.1
gi|23397572 kelch-like 34 [Homo sapiens] 31 1.4
gi|5174473 intracisternal A particle-promoted polypeptide isofor... 31 1.9
gi|223890235 intracisternal A particle-promoted polypeptide isof... 31 1.9
gi|21314675 kelch domain containing 4 [Homo sapiens] 31 1.9
gi|239835724 kelch-like 2, Mayven isoform 3 [Homo sapiens] 30 2.5
gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens] 30 2.5
>gi|55956888 kelch/ankyrin repeat containing cyclin A1 interacting
protein isoform a [Homo sapiens]
Length = 349
Score = 746 bits (1926), Expect = 0.0
Identities = 349/349 (100%), Positives = 349/349 (100%)
Query: 1 MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV 60
MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV
Sbjct: 1 MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV 60
Query: 61 FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW 120
FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW
Sbjct: 61 FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW 120
Query: 121 TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE 180
TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE
Sbjct: 121 TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE 180
Query: 181 GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKEEPPVAPHLME 240
GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKEEPPVAPHLME
Sbjct: 181 GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKEEPPVAPHLME 240
Query: 241 QLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPP 300
QLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPP
Sbjct: 241 QLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPP 300
Query: 301 LWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI 349
LWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI
Sbjct: 301 LWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI 349
>gi|55956890 kelch/ankyrin repeat containing cyclin A1 interacting
protein isoform b [Homo sapiens]
Length = 288
Score = 489 bits (1260), Expect = e-138
Identities = 229/229 (100%), Positives = 229/229 (100%)
Query: 1 MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV 60
MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV
Sbjct: 1 MAVAVPPGRAAGSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVV 60
Query: 61 FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW 120
FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW
Sbjct: 61 FDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAW 120
Query: 121 TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE 180
TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE
Sbjct: 121 TGTPGDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQE 180
Query: 181 GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIK 229
GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIK
Sbjct: 181 GCHTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIK 229
>gi|55956892 kelch/ankyrin repeat containing cyclin A1 interacting
protein isoform c [Homo sapiens]
Length = 111
Score = 241 bits (615), Expect = 7e-64
Identities = 111/111 (100%), Positives = 111/111 (100%)
Query: 239 MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS 298
MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS
Sbjct: 1 MEQLARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS 60
Query: 299 PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI 349
PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI
Sbjct: 61 PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGFGEDGRTASPQVCILDFI 111
>gi|7657301 kelch domain containing 2 [Homo sapiens]
Length = 406
Score = 43.5 bits (101), Expect = 3e-04
Identities = 70/283 (24%), Positives = 109/283 (38%), Gaps = 40/283 (14%)
Query: 79 RSHHDAAPVDGRWLCVVGGWDGSRRLAT---------VTALDTERGVWEAWTGTPGDCPP 129
RS H A DGR + V GG+ ++ + + E G W+ T GD PP
Sbjct: 32 RSGHVAVS-DGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKK-INTEGDVPP 89
Query: 130 AGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQEGCHTASRSG 189
+ S +C DR L + G G H++ Y L + R +++ C S
Sbjct: 90 S--MSGSCAVCVDRVLYLFG---GHHSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSS 144
Query: 190 HCAALLQTPGPHPGHQLLLFGGCN-LAEPEVAGHWSHGKIKEEPPVAP-------HLMEQ 241
+ ++L+ FGG L E +V G + + P H+++
Sbjct: 145 KDKLGVWVYK----NKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDT 200
Query: 242 LARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPPL 301
S + K P H+C+ VG +FGG R RD NDL+ + T
Sbjct: 201 ETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGG----RYRDARMNDLHYLNLDT---- 252
Query: 302 WFHFPCADRGMKRMGHR----TCLWNDQLYLVGGFGEDGRTAS 340
W +G+ +G T + +D L+L GGF D + S
Sbjct: 253 WEWNELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDKQPLS 295
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/285 (24%), Positives = 100/285 (35%), Gaps = 28/285 (9%)
Query: 12 GSGWAWRPVARDALLARAFHSCTELRGRFYLVGGLLA--GGA--REPSSDTVVFDPARGQ 67
G+GW ARD AF + G F GLLA GG D V+++ +
Sbjct: 211 GAGWWHNVSARDP----AFSARIGAAGAFLSPPGLLAVFGGQDLNNALGDLVLYNFSANT 266
Query: 68 AVRLGARGSPPRSHHDAAPVDGRWLCVVGGW--DGSRRLATVTALDTERGVWEAWTGTPG 125
+P H A L ++GG DGS RG WE
Sbjct: 267 WESWDLSPAPAARHSHVAVAWAGSLVLMGGELADGSLTNDVWAFSPLGRGHWELLAPPAS 326
Query: 126 DCP-PAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYK--QEGC 182
P GL+ H + D L V+G G ++ RLD ++ Y + G
Sbjct: 327 SSSGPPGLAGHAAALVDDVWLYVSG--GRTPHDLFSSGLFRFRLDSTSGGYWEQVIPAGG 384
Query: 183 HTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKEEPPVAPHLMEQL 242
+ +GH P LL+ GG P A E V H+ L
Sbjct: 385 RPPAATGHSMVFHA-----PSRALLVHGG---HRPSTARFSVRVNSTELFHVDRHVWTTL 436
Query: 243 ARLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTIC 287
G+ +GP H+ SV+G + V++GG T ++ C
Sbjct: 437 -----KGRDGLQGPRERAFHTASVLGNYMVVYGGNVHTHYQEEKC 476
Score = 39.3 bits (90), Expect = 0.005
Identities = 73/328 (22%), Positives = 113/328 (34%), Gaps = 55/328 (16%)
Query: 28 RAFHSCTEL---RGRFYLVGGLLAGGAREP----SSDTVVFDPARG-QAVRLGARGSPPR 79
R+FH+ + RG YL+GGL AGG + T+ + + Q V L P
Sbjct: 1499 RSFHAAAYVPAGRGAMYLLGGLTAGGVTRDFWVLNLTTLQWRQEKAPQTVEL-----PAV 1553
Query: 80 SHHDAAPVDGRWLCVVGGWDGSRRL-ATVTALDTERGVWEAWTGTPGDCPPAGLSSHTCT 138
+ H G L +VGG+ + G W +G PP GL H+
Sbjct: 1554 AGHTLTARRGLSLLLVGGYSPENGFNQQLLEYQLATGTWV--SGAQSGTPPTGLYGHSAV 1611
Query: 139 --RISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQEGC---HTASRSGHCAA 193
+D G + +Y+L + +G + G
Sbjct: 1612 YHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTWSLLAPSQGAKRDRMRNVRGSSRG 1671
Query: 194 LLQTPGPHPGHQLLLFGGCNLAEPEVAGHWS----HGKIKEEPPVAPHLMEQLARLVSSG 249
L Q PG PG G ++A W+ G EE ++PHL E RL
Sbjct: 1672 LGQVPGEQPGS-----WGFREVRKKMA-LWAALAGTGGFLEE--ISPHLKEPRPRL---- 1719
Query: 250 QGSQKGPHGLRHHSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTS----PPLWFHF 305
H+ +++G V+ GG + D +D+ +Y + P L
Sbjct: 1720 -----------FHASALLGDTMVVLGGRS---DPDEFSSDVLLYQVNCNAWLLPDLTRSA 1765
Query: 306 PCADRGMKRMGHRTCLWNDQLYLVGGFG 333
+ + H +LY+ GGFG
Sbjct: 1766 SVGPPMEESVAHAVAAVGSRLYISGGFG 1793
>gi|55925604 kelch-like 18 [Homo sapiens]
Length = 574
Score = 42.7 bits (99), Expect = 5e-04
Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 4/85 (4%)
Query: 33 CTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWL 92
CT + G Y VGGL + G + + VFDP R + RS A V+G L
Sbjct: 283 CTSIAGLIYAVGGLNSAG--DSLNVVEVFDPIANCWERCRPM-TTARSRVGVAVVNGL-L 338
Query: 93 CVVGGWDGSRRLATVTALDTERGVW 117
+GG+DG RL+TV A + E W
Sbjct: 339 YAIGGYDGQLRLSTVEAYNPETDTW 363
Score = 32.7 bits (73), Expect = 0.50
Identities = 31/133 (23%), Positives = 54/133 (40%), Gaps = 11/133 (8%)
Query: 22 RDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSH 81
R AR+ + G Y +GG + S ++P R+G+ S RS
Sbjct: 320 RPMTTARSRVGVAVVNGLLYAIGGY---DGQLRLSTVEAYNPETDTWTRVGSMNSK-RSA 375
Query: 82 HDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDCPPAGLSSHTCTRIS 141
+DG+ + V GG+DG+ L++V E W T + AG++ +
Sbjct: 376 MGTVVLDGQ-IYVCGGYDGNSSLSSVETYSPETDKWTVVTSMSSNRSAAGVT------VF 428
Query: 142 DRELQVAGREGGI 154
+ + V+G G+
Sbjct: 429 EGRIYVSGGHDGL 441
>gi|25188199 leucine carboxyl methyltransferase 2 [Homo sapiens]
Length = 686
Score = 39.7 bits (91), Expect = 0.004
Identities = 42/163 (25%), Positives = 67/163 (41%), Gaps = 7/163 (4%)
Query: 15 WAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGAR 74
W PV + AR HS +G + GGL G + EP + + P +
Sbjct: 521 WVRIPVEGEVPEARHSHSACTWQGGALIAGGL--GASEEPLNSVLFLRPISCGFLWESVD 578
Query: 75 GSPP---RSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDCP-PA 130
PP R H A ++G+ L V G W S VT ++ G+ + P P
Sbjct: 579 IQPPITPRYSHTAHVLNGKLLLVGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWPL 638
Query: 131 GLSSHTCTRI-SDRELQVAGREGGIHTQRRYGSIYTLRLDPSA 172
L +HT + +++L + G G + Y + +T+ LD S+
Sbjct: 639 MLHNHTSILLPEEQQLLLLGGGGNCFSFGTYFNPHTVTLDLSS 681
>gi|24475847 influenza virus NS1A binding protein [Homo sapiens]
Length = 642
Score = 38.9 bits (89), Expect = 0.007
Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 26 LARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAA 85
+AR L G+ ++ GG A S ++DP R + +G SP RS+ A
Sbjct: 547 VARRGAGVAVLNGKLFVCGGFDGSHA---ISCVEMYDPTRNEWKMMGNMTSP-RSNAGIA 602
Query: 86 PVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWT 121
V G + VGG+DG+ L TV + E W +T
Sbjct: 603 TV-GNTIYAVGGFDGNEFLNTVEVYNLESNEWSPYT 637
Score = 30.0 bits (66), Expect = 3.2
Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPP--RSHHDAAPVDGRWLC 93
L G+ Y+VGG G ++ + VFDP +L +P R H A G +L
Sbjct: 461 LNGKLYIVGGSDPYG-QKGLKNCDVFDPV----TKLWTSCAPLNIRRHQSAVCELGGYLY 515
Query: 94 VVGGWDGSRRLATVTALDTERGVW 117
++GG + L TV + E W
Sbjct: 516 IIGGAESWNCLNTVERYNPENNTW 539
>gi|17017980 kelch-like 4 isoform 2 [Homo sapiens]
Length = 720
Score = 36.2 bits (82), Expect = 0.045
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 38 GRFYLVGGLLAGGAREPS--SDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
G Y+VGG A + S SD V +G + A S PR P+ G L VV
Sbjct: 617 GFLYVVGGHDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPL-GDKLYVV 675
Query: 96 GGWDGSRRLATVTALDTERGVWE 118
GG+DG L TV + D +R W+
Sbjct: 676 GGYDGHTYLNTVESYDAQRNEWK 698
>gi|17017982 kelch-like 4 isoform 1 [Homo sapiens]
Length = 718
Score = 36.2 bits (82), Expect = 0.045
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 3/83 (3%)
Query: 38 GRFYLVGGLLAGGAREPS--SDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
G Y+VGG A + S SD V +G + A S PR P+ G L VV
Sbjct: 617 GFLYVVGGHDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPL-GDKLYVV 675
Query: 96 GGWDGSRRLATVTALDTERGVWE 118
GG+DG L TV + D +R W+
Sbjct: 676 GGYDGHTYLNTVESYDAQRNEWK 698
>gi|38194229 kelch-like 17 [Homo sapiens]
Length = 642
Score = 36.2 bits (82), Expect = 0.045
Identities = 32/108 (29%), Positives = 42/108 (38%), Gaps = 16/108 (14%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W PVA L R+ L G Y+ GG + T + + + GA S
Sbjct: 510 WSPVA-SMLSRRSSAGVAVLEGALYVAGG---------NDGTSCLNSVERYSPKAGAWES 559
Query: 77 PP-----RSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEA 119
RS HD +DG WL VGG DGS L ++ + W A
Sbjct: 560 VAPMNIRRSTHDLVAMDG-WLYAVGGNDGSSSLNSIEKYNPRTNKWVA 606
Score = 32.7 bits (73), Expect = 0.50
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 5/82 (6%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
L G Y GG + +DP G + A S R + A +DG L V
Sbjct: 434 LHGLLYSAGGYDGASCLNSAER---YDPLTGTWTSVAAM-STRRRYVRVATLDGN-LYAV 488
Query: 96 GGWDGSRRLATVTALDTERGVW 117
GG+D S LATV + + VW
Sbjct: 489 GGYDSSSHLATVEKYEPQVNVW 510
Score = 32.3 bits (72), Expect = 0.65
Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 16/94 (17%)
Query: 89 GRWLCVVGGWDGSRRLATVTALDTERGVW--EAWTGTPGDC-----------PPAGLSSH 135
G L VGG+DG+ LATV + D W E GT C G
Sbjct: 388 GNRLYAVGGYDGTSDLATVESYDPVTNTWQPEVSMGTRRSCLGVAALHGLLYSAGGYDGA 447
Query: 136 TCTRISDRELQVAG---REGGIHTQRRYGSIYTL 166
+C ++R + G + T+RRY + TL
Sbjct: 448 SCLNSAERYDPLTGTWTSVAAMSTRRRYVRVATL 481
>gi|148664209 kelch-like 10 [Homo sapiens]
Length = 608
Score = 35.8 bits (81), Expect = 0.059
Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W V + RA+H L+G Y++GG + + + FDP + ++ S
Sbjct: 318 WVNVTCEEESPRAYHGAAYLKGYVYIIGGF---DSVDYFNSVKRFDPVKKTWHQVAPMHS 374
Query: 77 PPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVW 117
R + + V G ++ +GG+DG RL T + E W
Sbjct: 375 --RRCYVSVTVLGNFIYAMGGFDGYVRLNTAERYEPETNQW 413
>gi|88196794 kelch-like 35 [Homo sapiens]
Length = 363
Score = 35.8 bits (81), Expect = 0.059
Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 14/143 (9%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W P+ R+ + LR Y+ GG + S D +F +++ +
Sbjct: 109 WTPLPSLPGYTRSEFAACALRNDVYVSGGHIN------SHDVWMFSSHLHTWIKVASLHK 162
Query: 77 PPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDCPPAGLSSHT 136
R H A V G+ L VGG+DG RRL +V D W A P +SS
Sbjct: 163 G-RWRHKMAVVQGQ-LFAVGGFDGLRRLHSVERYDPFSNTWAAAAPL-----PEAVSSAA 215
Query: 137 CTRISDRELQVAG-REGGIHTQR 158
+ + + G R+GG++T +
Sbjct: 216 VASCAGKLFVIGGARQGGVNTDK 238
>gi|16945972 kelch domain containing 3 [Homo sapiens]
Length = 382
Score = 35.8 bits (81), Expect = 0.059
Identities = 63/279 (22%), Positives = 102/279 (36%), Gaps = 52/279 (18%)
Query: 75 GSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTE--RGVWEAWTGTP-------G 125
G P R +H A V G + GG+ T+ +D V WT P G
Sbjct: 10 GGPRRVNHAAVAV-GHRVYSFGGYCSGEDYETLRQIDVHIFNAVSLRWTKLPPVKSAIRG 68
Query: 126 DCP--PAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQEGCH 183
P P H+ I D L GR T+ +Y ++ + + + + G
Sbjct: 69 QAPVVPYMRYGHSTVLIDDTVLLWGGRND---TEGACNVLYAFDVN-THKWFTPRVSGTV 124
Query: 184 TASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKEEPPVAPHLMEQLA 243
+R GH A +L G + +FGG + A +S+ K + +
Sbjct: 125 PGARDGHSACVL-------GKIMYIFGGYE----QQADCFSNDIHKLDTSTMTWTL---- 169
Query: 244 RLVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGGET-----LTRARDTICNDLYIYDTRTS 298
+ + G ++ HS +++G +FGG + CN + ++DTRT
Sbjct: 170 -ICTKGSPARWRDF----HSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTE 224
Query: 299 -----PPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGF 332
PP P G R H +N +LY+ GG+
Sbjct: 225 AWLDCPPT----PVLPEG--RRSHSAFGYNGELYIFGGY 257
Score = 32.3 bits (72), Expect = 0.65
Identities = 25/88 (28%), Positives = 37/88 (42%), Gaps = 8/88 (9%)
Query: 262 HSCSVVGPFAVLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMK--RMGHRT 319
HS ++ +L+GG T CN LY +D T WF P + R GH
Sbjct: 80 HSTVLIDDTVLLWGGRNDTEGA---CNVLYAFDVNTHK--WFT-PRVSGTVPGARDGHSA 133
Query: 320 CLWNDQLYLVGGFGEDGRTASPQVCILD 347
C+ +Y+ GG+ + S + LD
Sbjct: 134 CVLGKIMYIFGGYEQQADCFSNDIHKLD 161
>gi|34101268 kelch-like 8 [Homo sapiens]
Length = 620
Score = 35.0 bits (79), Expect = 0.100
Identities = 35/119 (29%), Positives = 53/119 (44%), Gaps = 7/119 (5%)
Query: 28 RAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPV 87
RA + ++L G Y+VGG P S +DP + + A + PR A V
Sbjct: 497 RAGNGVSKLHGCLYVVGGF---DDNSPLSSVERYDPRSNKWDYVAAL-TTPRGGVGIATV 552
Query: 88 DGRWLCVVGGWDGSRRLATVTALDTERGVWEAWTGTPGDC-PPAGLSSHTCTRISDREL 145
G+ + VGG +G+ L TV A D WE G+ C AG++ +C R++
Sbjct: 553 MGK-IFAVGGHNGNAYLNTVEAFDPVLNRWEL-VGSVSHCRAGAGVAVCSCLTSQIRDV 609
>gi|41393547 neuroblastoma-amplified protein [Homo sapiens]
Length = 2371
Score = 34.7 bits (78), Expect = 0.13
Identities = 17/34 (50%), Positives = 19/34 (55%)
Query: 183 HTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAE 216
H S S H + T HPGH+LLL GGC AE
Sbjct: 227 HCFSFSSHYPHGINTAIYHPGHRLLLVGGCETAE 260
>gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens]
Length = 589
Score = 33.5 bits (75), Expect = 0.29
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 2/89 (2%)
Query: 46 LLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLA 105
++ G ++ FD Q R+G + S H A G L VVGG+ G++R
Sbjct: 496 IMGGDTEFTAASAYRFDCETNQWTRIGDMTAKRMSCHALA--SGNKLYVVGGYFGTQRCK 553
Query: 106 TVTALDTERGVWEAWTGTPGDCPPAGLSS 134
T+ D W T P P S
Sbjct: 554 TLDCYDPTSDTWNCITTVPYSLIPTAFVS 582
>gi|31881798 muskelin 1, intracellular mediator containing kelch
motifs isoform 2 [Homo sapiens]
Length = 735
Score = 32.7 bits (73), Expect = 0.50
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 66 GQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWT-GTP 124
G+ R G RG H V + + GGWDG++ LA A + W + T
Sbjct: 263 GEDNRPGMRGG----HQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTE 318
Query: 125 GDCPPAGLSSH-TCTRISDRELQVAGR 150
+ P+ S H C I R++ GR
Sbjct: 319 KENGPSARSCHKMCIDIQRRQIYTLGR 345
>gi|223890246 muskelin 1, intracellular mediator containing kelch
motifs isoform 1 [Homo sapiens]
Length = 712
Score = 32.7 bits (73), Expect = 0.50
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 66 GQAVRLGARGSPPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVWEAWT-GTP 124
G+ R G RG H V + + GGWDG++ LA A + W + T
Sbjct: 240 GEDNRPGMRGG----HQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTE 295
Query: 125 GDCPPAGLSSH-TCTRISDRELQVAGR 150
+ P+ S H C I R++ GR
Sbjct: 296 KENGPSARSCHKMCIDIQRRQIYTLGR 322
>gi|26190616 kelch domain containing 1 [Homo sapiens]
Length = 406
Score = 32.7 bits (73), Expect = 0.50
Identities = 43/174 (24%), Positives = 63/174 (36%), Gaps = 26/174 (14%)
Query: 125 GDCPPAGLSSHTCTRISDRELQVAGREGGIHTQRRYGSIYTLRLDPSARTYCYKQEGCHT 184
G PP ++HTC + ++ GR Q R ++ L LD + G
Sbjct: 190 GGVPPQPRAAHTCAVLGNKGYIFGGRV----LQTRMNDLHYLNLDTWTWSGRITINGESP 245
Query: 185 ASRSGHCAALLQTPGPHPGHQLLLFGGCNLAEPEVAGHWSHGKIKEEPPVAPHLMEQLAR 244
RS H T P +L L GG + ++ W H V + +QL
Sbjct: 246 KHRSWH------TLTPIADDKLFLCGGLSADNIPLSDGWIHN-------VTTNCWKQLTH 292
Query: 245 LVSSGQGSQKGPHGLRHHSCSVVGPFAVLFGG--ETLTRARDTICNDLYIYDTR 296
L K L H +C ++FGG + L CNDL I+ T+
Sbjct: 293 L-------PKTRPRLWHTACLGKENEIMVFGGSKDDLLALDTGHCNDLLIFQTQ 339
>gi|46410931 attractin-like 1 [Homo sapiens]
Length = 1379
Score = 32.3 bits (72), Expect = 0.65
Identities = 20/76 (26%), Positives = 29/76 (38%), Gaps = 5/76 (6%)
Query: 262 HSCSVVGPFAVLFGGET-----LTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMG 316
HS ++ ++FGG T L+ D YD P R + R G
Sbjct: 524 HSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFG 583
Query: 317 HRTCLWNDQLYLVGGF 332
H + N +Y+ GGF
Sbjct: 584 HSAVVINGSMYIFGGF 599
>gi|40018614 DRE1 protein [Homo sapiens]
Length = 600
Score = 32.0 bits (71), Expect = 0.85
Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 8/101 (7%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W+ +A+ ++ ++ LR +L G R S D +++ +R+ +
Sbjct: 342 WKSLAKLPEFTKSEYAVCALRN------DILVSGGRINSRDVWIYNSQLNIWIRVASLNK 395
Query: 77 PPRSHHDAAPVDGRWLCVVGGWDGSRRLATVTALDTERGVW 117
R H A + G+ + VVGG+DG RL++V D+ W
Sbjct: 396 G-RWRHKMAVLLGK-VYVVGGYDGQNRLSSVECYDSFSNRW 434
>gi|21450863 attractin isoform 2 [Homo sapiens]
Length = 1272
Score = 31.6 bits (70), Expect = 1.1
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 9/78 (11%)
Query: 262 HSCSVVGPFAVLFGGET-----LTRARDTICNDLYIYDTRTSPPLWFHFPCAD--RGMKR 314
H+ +V ++FGG T ++ +D YD W P D + R
Sbjct: 557 HTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDR--WSVLPRPDLHHDVNR 614
Query: 315 MGHRTCLWNDQLYLVGGF 332
GH L N +Y+ GGF
Sbjct: 615 FGHSAVLHNSTMYVFGGF 632
>gi|21450861 attractin isoform 1 [Homo sapiens]
Length = 1429
Score = 31.6 bits (70), Expect = 1.1
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 9/78 (11%)
Query: 262 HSCSVVGPFAVLFGGET-----LTRARDTICNDLYIYDTRTSPPLWFHFPCAD--RGMKR 314
H+ +V ++FGG T ++ +D YD W P D + R
Sbjct: 557 HTAVIVSGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDR--WSVLPRPDLHHDVNR 614
Query: 315 MGHRTCLWNDQLYLVGGF 332
GH L N +Y+ GGF
Sbjct: 615 FGHSAVLHNSTMYVFGGF 632
>gi|23397572 kelch-like 34 [Homo sapiens]
Length = 644
Score = 31.2 bits (69), Expect = 1.4
Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 15/110 (13%)
Query: 15 WAWRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGAR 74
W P R+A RA C + R VGGL AGG E + ++D R R A
Sbjct: 405 WTEVPAMREA---RAHFWCGAVGERLLAVGGLGAGG--EVLASVEMYDLRRD---RWTAA 456
Query: 75 GSPPRS-HHDAAPVDGRWLCVVGGW------DGSRRLATVTALDTERGVW 117
G+ PR+ H A V R + + G G+ L + L E VW
Sbjct: 457 GALPRALHGHAGAVGDRGVVYISGGKAGRGEGGASSLRDLYVLGPEEQVW 506
>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
[Homo sapiens]
Length = 584
Score = 30.8 bits (68), Expect = 1.9
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W V A+ +R + C E++G Y++GG+ G S + V+DP + L G+
Sbjct: 417 WEVVGNMAV-SRYYFGCCEMQGLIYVIGGISNEGIELRSFE--VYDPLSKRWSPLPPMGT 473
Query: 77 PPRSHHDAAPVDGRWLCV--VGGWDGSR-RLATVTALDTERGVW 117
R++ A ++ C+ VGGW+ ++ L TV E W
Sbjct: 474 -RRAYLGVAALND---CIYSVGGWNETQDALHTVEKYSFEEEKW 513
>gi|223890235 intracisternal A particle-promoted polypeptide isoform
2 [Homo sapiens]
Length = 582
Score = 30.8 bits (68), Expect = 1.9
Identities = 29/104 (27%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
Query: 17 WRPVARDALLARAFHSCTELRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGS 76
W V A+ +R + C E++G Y++GG+ G S + V+DP + L G+
Sbjct: 417 WEVVGNMAV-SRYYFGCCEMQGLIYVIGGISNEGIELRSFE--VYDPLSKRWSPLPPMGT 473
Query: 77 PPRSHHDAAPVDGRWLCV--VGGWDGSR-RLATVTALDTERGVW 117
R++ A ++ C+ VGGW+ ++ L TV E W
Sbjct: 474 -RRAYLGVAALND---CIYSVGGWNETQDALHTVEKYSFEEEKW 513
>gi|21314675 kelch domain containing 4 [Homo sapiens]
Length = 520
Score = 30.8 bits (68), Expect = 1.9
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 5/63 (7%)
Query: 272 VLFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMGHRTCL---WNDQLYL 328
+LFGGE + + N+LY+Y+TR W +R H+ + QL++
Sbjct: 79 ILFGGEYFNGQKTFLYNELYVYNTRKD--TWTKVDIPSPPPRRCAHQAVVVPQGGGQLWV 136
Query: 329 VGG 331
GG
Sbjct: 137 FGG 139
Score = 30.0 bits (66), Expect = 3.2
Identities = 18/65 (27%), Positives = 25/65 (38%)
Query: 273 LFGGETLTRARDTICNDLYIYDTRTSPPLWFHFPCADRGMKRMGHRTCLWNDQLYLVGGF 332
+FGGE + + + ++ + W R GHR W QL L GGF
Sbjct: 136 VFGGEFASPNGEQFYHYKDLWVLHLATKTWEQVKSTGGPSGRSGHRMVAWKRQLILFGGF 195
Query: 333 GEDGR 337
E R
Sbjct: 196 HESTR 200
>gi|239835724 kelch-like 2, Mayven isoform 3 [Homo sapiens]
Length = 505
Score = 30.4 bits (67), Expect = 2.5
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
+ G + VGG G R + D+ +DP + Q + A RS AA ++G L V
Sbjct: 263 MAGLVFAVGGF-NGSLRVRTVDS--YDPVKDQWTSV-ANMRDRRSTLGAAVLNGL-LYAV 317
Query: 96 GGWDGSRRLATVTALDTERGVW 117
GG+DGS L++V A + + W
Sbjct: 318 GGFDGSTGLSSVEAYNIKSNEW 339
>gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens]
Length = 597
Score = 30.4 bits (67), Expect = 2.5
Identities = 27/82 (32%), Positives = 41/82 (50%), Gaps = 5/82 (6%)
Query: 36 LRGRFYLVGGLLAGGAREPSSDTVVFDPARGQAVRLGARGSPPRSHHDAAPVDGRWLCVV 95
+ G + VGG G R + D+ +DP + Q + A RS AA ++G L V
Sbjct: 355 MAGLVFAVGGF-NGSLRVRTVDS--YDPVKDQWTSV-ANMRDRRSTLGAAVLNGL-LYAV 409
Query: 96 GGWDGSRRLATVTALDTERGVW 117
GG+DGS L++V A + + W
Sbjct: 410 GGFDGSTGLSSVEAYNIKSNEW 431
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.465
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,939,481
Number of Sequences: 37866
Number of extensions: 860987
Number of successful extensions: 2007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 1916
Number of HSP's gapped (non-prelim): 118
length of query: 349
length of database: 18,247,518
effective HSP length: 103
effective length of query: 246
effective length of database: 14,347,320
effective search space: 3529440720
effective search space used: 3529440720
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.