Search of human proteins with 5453621

Search of human proteins with 5453621

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453621 solute carrier family 35 (CMP-sialic acid
transporter), member A1 [Homo sapiens]
         (337 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5453621 solute carrier family 35 (CMP-sialic acid transporter...   650   0.0  
gi|109948265 solute carrier family 35, member A2 isoform c [Homo...   269   3e-72
gi|5032211 solute carrier family 35, member A2 isoform a [Homo s...   269   3e-72
gi|6912668 solute carrier family 35 member 3A [Homo sapiens]          237   1e-62
gi|8923657 solute carrier family 35, member A5 [Homo sapiens]         100   2e-21
gi|18087849 solute carrier family 35, member A4 [Homo sapiens]         94   1e-19
gi|73808086 solute carrier family 35, member A2 isoform b [Homo ...    76   5e-14
gi|160707905 similar to solute carrier family 35, member E2 [Hom...    45   7e-05
gi|223671915 GDP-fucose transporter 1 isoform a [Homo sapiens]         37   0.019
gi|223671919 GDP-fucose transporter 1 isoform b [Homo sapiens]         37   0.019
gi|223671917 GDP-fucose transporter 1 isoform b [Homo sapiens]         37   0.019
gi|14249528 solute carrier family 35, member B4 [Homo sapiens]         35   0.073
gi|31542711 ANT2-binding protein [Homo sapiens]                        32   1.1  
gi|5032213 solute carrier family 35, member B1 [Homo sapiens]          32   1.1  
gi|76159293 thioesterase superfamily member 4 [Homo sapiens]           31   1.4  
gi|238814322 aldehyde dehydrogenase 1 family, member L2 [Homo sa...    31   1.8  
gi|21536378 ATP-binding cassette, sub-family B (MDR/TAP), member...    29   5.2  
gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo...    29   6.8  
gi|196123580 NADH dehydrogenase subunit 2 [Homo sapiens neandert...    28   8.9  
gi|251831108 NADH dehydrogenase subunit 2 [Homo sapiens]               28   8.9  

>gi|5453621 solute carrier family 35 (CMP-sialic acid transporter),
           member A1 [Homo sapiens]
          Length = 337

 Score =  650 bits (1678), Expect = 0.0
 Identities = 337/337 (100%), Positives = 337/337 (100%)

Query: 1   MAAPRDNVTLLFKLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSV 60
           MAAPRDNVTLLFKLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSV
Sbjct: 1   MAAPRDNVTLLFKLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSV 60

Query: 61  GILAKETGSLGRFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVT 120
           GILAKETGSLGRFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVT
Sbjct: 61  GILAKETGSLGRFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVT 120

Query: 121 YQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVVVEQNPLLGFGA 180
           YQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVVVEQNPLLGFGA
Sbjct: 121 YQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVVVEQNPLLGFGA 180

Query: 181 IAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFY 240
           IAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFY
Sbjct: 181 IAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFY 240

Query: 241 GYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFA 300
           GYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFA
Sbjct: 241 GYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFA 300

Query: 301 LGTLLVCVSIYLYGLPRQDTTSIQQGETASKERVIGV 337
           LGTLLVCVSIYLYGLPRQDTTSIQQGETASKERVIGV
Sbjct: 301 LGTLLVCVSIYLYGLPRQDTTSIQQGETASKERVIGV 337


>gi|109948265 solute carrier family 35, member A2 isoform c [Homo
           sapiens]
          Length = 393

 Score =  269 bits (687), Expect = 3e-72
 Identities = 146/320 (45%), Positives = 210/320 (65%), Gaps = 2/320 (0%)

Query: 13  KLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGIL-AKETGSLG 71
           K   LAV+ +  A   +++RY RT   + +F+TTAV + EV+K L  + +L A++ G++ 
Sbjct: 36  KYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVK 95

Query: 72  RFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALC 131
                L E VL    + LKL+VPSL+Y +QNN+ ++A+SNL AA +QVTYQLKI  TAL 
Sbjct: 96  HLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTALF 155

Query: 132 TVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKV-VVEQNPLLGFGAIAIAVLCSGF 190
           +VLMLNR+LS+LQW S+ +L  GV +VQ + A       ++QNP  G  A+  + L SGF
Sbjct: 156 SVLMLNRSLSRLQWASLLLLFTGVAIVQAQQAGGGGPRPLDQNPGAGLAAVVASCLSSGF 215

Query: 191 AGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYGYTYYVWFVI 250
           AGVYFEK+LK S  S+W+RN+Q+ L G  + L G++ ++G  +  +GFF+GYT  VW V+
Sbjct: 216 AGVYFEKILKGSSGSVWLRNLQLGLFGTALGLVGLWWAEGTAVATRGFFFGYTPAVWGVV 275

Query: 251 FLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTLLVCVSI 310
              + GGL  +VVVKY DNI+KGF+ + +IVLST+AS+ LFG  +   FALG  LV  ++
Sbjct: 276 LNQAFGGLLVAVVVKYADNILKGFATSLSIVLSTVASIRLFGFHVDPLFALGAGLVIGAV 335

Query: 311 YLYGLPRQDTTSIQQGETAS 330
           YLY LPR    +I     ++
Sbjct: 336 YLYSLPRGAAKAIASASASA 355


>gi|5032211 solute carrier family 35, member A2 isoform a [Homo
           sapiens]
          Length = 396

 Score =  269 bits (687), Expect = 3e-72
 Identities = 146/320 (45%), Positives = 210/320 (65%), Gaps = 2/320 (0%)

Query: 13  KLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGIL-AKETGSLG 71
           K   LAV+ +  A   +++RY RT   + +F+TTAV + EV+K L  + +L A++ G++ 
Sbjct: 36  KYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVK 95

Query: 72  RFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALC 131
                L E VL    + LKL+VPSL+Y +QNN+ ++A+SNL AA +QVTYQLKI  TAL 
Sbjct: 96  HLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQVTYQLKILTTALF 155

Query: 132 TVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKV-VVEQNPLLGFGAIAIAVLCSGF 190
           +VLMLNR+LS+LQW S+ +L  GV +VQ + A       ++QNP  G  A+  + L SGF
Sbjct: 156 SVLMLNRSLSRLQWASLLLLFTGVAIVQAQQAGGGGPRPLDQNPGAGLAAVVASCLSSGF 215

Query: 191 AGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYGYTYYVWFVI 250
           AGVYFEK+LK S  S+W+RN+Q+ L G  + L G++ ++G  +  +GFF+GYT  VW V+
Sbjct: 216 AGVYFEKILKGSSGSVWLRNLQLGLFGTALGLVGLWWAEGTAVATRGFFFGYTPAVWGVV 275

Query: 251 FLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTLLVCVSI 310
              + GGL  +VVVKY DNI+KGF+ + +IVLST+AS+ LFG  +   FALG  LV  ++
Sbjct: 276 LNQAFGGLLVAVVVKYADNILKGFATSLSIVLSTVASIRLFGFHVDPLFALGAGLVIGAV 335

Query: 311 YLYGLPRQDTTSIQQGETAS 330
           YLY LPR    +I     ++
Sbjct: 336 YLYSLPRGAAKAIASASASA 355


>gi|6912668 solute carrier family 35 member 3A [Homo sapiens]
          Length = 325

 Score =  237 bits (604), Expect = 1e-62
 Identities = 129/309 (41%), Positives = 190/309 (61%), Gaps = 8/309 (2%)

Query: 13  KLYCLAVMTLMAAVYTIALRYTRTSDKE--LYFSTTAVCITEVIKLLLSVGILAKETG-S 69
           K   L ++        + +RY+RT  +E   Y S+TAV + E++K++  + ++ K++  S
Sbjct: 6   KYVSLGILVFQTTSLVLTMRYSRTLKEEGPRYLSSTAVVVAELLKIMACILLVYKDSKCS 65

Query: 70  LGRFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTA 129
           L      L + +L  P E LKL++PS +Y +QNN+ ++ALSNLDAA YQVTYQLKI  TA
Sbjct: 66  LRALNRVLHDEILNKPMETLKLAIPSGIYTLQNNLLYVALSNLDAATYQVTYQLKILTTA 125

Query: 130 LCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQA---TKVVVEQNPLLGFGAIAIAVL 186
           L +V ML++ L   QW+S+ +L  GV  VQW P+ +   +K +   +  +G  A+  A  
Sbjct: 126 LFSVSMLSKKLGVYQWLSLVILMTGVAFVQW-PSDSQLDSKELSAGSQFVGLMAVLTACF 184

Query: 187 CSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYGYTYYV 246
            SGFAGVYFEK+LK +  S+W+RNIQ+   G I  L GVY+ DG  + + GFF GY    
Sbjct: 185 SSGFAGVYFEKILKETKQSVWIRNIQLGFFGSIFGLMGVYIYDGELVSKNGFFQGYNRLT 244

Query: 247 WFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVM-LFGLQITLTFALGTLL 305
           W V+ L ++GGL  + V+KY DNI+KGF+ + +I+LST+ S   L     T  F LG +L
Sbjct: 245 WIVVVLQALGGLVIAAVIKYADNILKGFATSLSIILSTLISYFWLQDFVPTSVFFLGAIL 304

Query: 306 VCVSIYLYG 314
           V  + +LYG
Sbjct: 305 VITATFLYG 313


>gi|8923657 solute carrier family 35, member A5 [Homo sapiens]
          Length = 424

 Score =  100 bits (248), Expect = 2e-21
 Identities = 88/355 (24%), Positives = 157/355 (44%), Gaps = 64/355 (18%)

Query: 18  AVMTLMAAVYTIALRYTRTSDKEL-YFSTTAVCITEVIKL----LLSVGILAKETGSLGR 72
           A+   +++   + ++Y+   + +  Y  TT    +E++KL    L+S  ++ K+  S   
Sbjct: 24  AIFIALSSSRILLVKYSANEENKYDYLPTTVNVCSELVKLVFCVLVSFCVIKKDHQSRNL 83

Query: 73  FKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCT 132
             AS +E       + +K S+P+ +Y + N + F  LS L  A+  +     I  TAL  
Sbjct: 84  KYASWKEF-----SDFMKWSIPAFLYFLDNLIVFYVLSYLQPAMAVIFSNFSIITTALLF 138

Query: 133 VLMLNRTLSKLQWVSVFMLCAGV------------------------------------- 155
            ++L R L+ +QW S+  L   +                                     
Sbjct: 139 RIVLKRRLNWIQWASLLTLFLSIVALTAGTKTLQHNLAGRGFHHDAFFSPSNSCLLFRSE 198

Query: 156 -------TLVQWKPAQA---TKVVVEQNPLLGFGAIAIAVLC--SGFAGVYFEKVLKSSD 203
                  T  +W   +A   T   V  +  LG G + I V C  S  A +Y EK+LK  +
Sbjct: 199 CPRKDNCTAKEWTFPEAKWNTTARVFSHIRLGMGHVLIIVQCFISSMANIYNEKILKEGN 258

Query: 204 T---SLWVRNIQMYLSGIIVT--LAGVYLSDGAEIKEKGFFYGYTYYVWFVIFLASVGGL 258
               S++++N ++Y  GI+      G+  S+  +IK  GFFYG++ +   +IF+ +  GL
Sbjct: 259 QLTESIFIQNSKLYFFGILFNGLTLGLQRSNRDQIKNCGFFYGHSAFSVALIFVTAFQGL 318

Query: 259 YTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTLLVCVSIYLY 313
             + ++K+ DN+     A    V+ T  SV++F  + +L F L    V +SI++Y
Sbjct: 319 SVAFILKFLDNMFHVLMAQVTTVIITTVSVLVFDFRPSLEFFLEAPSVLLSIFIY 373


>gi|18087849 solute carrier family 35, member A4 [Homo sapiens]
          Length = 324

 Score = 94.4 bits (233), Expect = 1e-19
 Identities = 80/312 (25%), Positives = 142/312 (45%), Gaps = 29/312 (9%)

Query: 17  LAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGILAKETGSLGRFKAS 76
           L + T M   +   L       +  +  ++AV +TE+ KLLL    L     +  +    
Sbjct: 23  LLLSTAMYGAHAPLLALCHVDGRVPFRPSSAVLLTELTKLLLCAFSLLVGWQAWPQ---- 78

Query: 77  LRENVLGSP--KELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVL 134
                 G P  ++    ++ +L+Y   NN+       +D + YQV   LKI  TA+   L
Sbjct: 79  ------GPPPWRQAAPFALSALLYGANNNLVIYLQRYMDPSTYQVLSNLKIGSTAVLYCL 132

Query: 135 MLNRTLSKLQWVSVFMLCA-------------GVTLVQWKPAQATKVVVEQNPLLGFGAI 181
            L   LS  Q +++ +L A             G TL    PA A   +      LG   +
Sbjct: 133 CLRHRLSVRQGLALLLLMAAGACYAAGGLQVPGNTLPSPPPAAAASPMPLHITPLGLLLL 192

Query: 182 AIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYG 241
            +  L SG + VY E ++K     L ++N+ +Y  G+++ L G++   G+     G   G
Sbjct: 193 ILYCLISGLSSVYTELLMKRQRLPLALQNLFLYTFGVLLNL-GLHAGGGSG---PGLLEG 248

Query: 242 YTYYVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFAL 301
           ++ +   V+   ++ GL  S V+K+  +I + F  + ++V++ + S +L  LQ+T  F L
Sbjct: 249 FSGWAALVVLSQALNGLLMSAVMKHGSSITRLFVVSCSLVVNAVLSAVLLRLQLTAAFFL 308

Query: 302 GTLLVCVSIYLY 313
            TLL+ +++ LY
Sbjct: 309 ATLLIGLAMRLY 320


>gi|73808086 solute carrier family 35, member A2 isoform b [Homo
           sapiens]
          Length = 242

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 43/107 (40%), Positives = 68/107 (63%), Gaps = 1/107 (0%)

Query: 13  KLYCLAVMTLMAAVYTIALRYTRTSDKELYFSTTAVCITEVIKLLLSVGIL-AKETGSLG 71
           K   LAV+ +  A   +++RY RT   + +F+TTAV + EV+K L  + +L A++ G++ 
Sbjct: 36  KYISLAVLVVQNASLILSIRYARTLPGDRFFATTAVVMAEVLKGLTCLLLLFAQKRGNVK 95

Query: 72  RFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQ 118
                L E VL    + LKL+VPSL+Y +QNN+ ++A+SNL AA +Q
Sbjct: 96  HLVLFLHEAVLVQYVDTLKLAVPSLIYTLQNNLQYVAISNLPAATFQ 142


>gi|160707905 similar to solute carrier family 35, member E2 [Homo
           sapiens]
          Length = 405

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 49/170 (28%), Positives = 71/170 (41%), Gaps = 15/170 (8%)

Query: 175 LLGFGAIAIAVLCSGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTL---AGVYLSDGA 231
           +LGF A     +      V+ +K+L           +Q Y S   V +   A V+ +D  
Sbjct: 222 VLGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVAMLVPARVFFTDVP 281

Query: 232 EIKEKGFFYGYTYYVWFVIFLASVGGLYTSVVVKYTDNIMKG------FSAAAAI--VLS 283
            I   G  + Y   V  V+ L + G L+    V  T   + G      FS A+ +   LS
Sbjct: 282 VIGRSGKSFSYNQDV--VLLLLTDGVLFHLQSV--TAYALMGKISPVTFSVASTVKHALS 337

Query: 284 TIASVMLFGLQITLTFALGTLLVCVSIYLYGLPRQDTTSIQQGETASKER 333
              SV++FG +IT   A+GT LV V + LY   RQ      Q   A+  R
Sbjct: 338 IWLSVIVFGNKITSLSAVGTALVTVGVLLYNKARQHQQEALQSLAAATGR 387


>gi|223671915 GDP-fucose transporter 1 isoform a [Homo sapiens]
          Length = 364

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 48/211 (22%), Positives = 83/211 (39%), Gaps = 15/211 (7%)

Query: 86  KELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQW 145
           + +L LSV  +     NN   L L  +  A Y V   L      L + L+L +T S    
Sbjct: 115 RSVLPLSVVFIGMITFNN---LCLKYVGVAFYNVGRSLTTVFNVLLSYLLLKQTTSFYAL 171

Query: 146 VSVFMLCAGVTL-VQWKPAQATKVVVEQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDT 204
           ++  ++  G  L V  + A+ T         LG     +A LC     +Y  KVL + D 
Sbjct: 172 LTCGIIIGGFWLGVDQEGAEGTL------SWLGTVFGVLASLCVSLNAIYTTKVLPAVDG 225

Query: 205 SLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYGYTYYVWFVIFLASVGGL----YT 260
           S+W       ++  I+ L  + L    +        G  ++ W ++ L  + G      T
Sbjct: 226 SIWRLTFYNNVNACILFLPLLLLLGELQALRDFAQLGSAHF-WGMMTLGGLFGFAIGYVT 284

Query: 261 SVVVKYTDNIMKGFSAAAAIVLSTIASVMLF 291
            + +K+T  +    S  A     T+ +V+ +
Sbjct: 285 GLQIKFTSPLTHNVSGTAKACAQTVLAVLYY 315


>gi|223671919 GDP-fucose transporter 1 isoform b [Homo sapiens]
          Length = 351

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 48/211 (22%), Positives = 83/211 (39%), Gaps = 15/211 (7%)

Query: 86  KELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQW 145
           + +L LSV  +     NN   L L  +  A Y V   L      L + L+L +T S    
Sbjct: 102 RSVLPLSVVFIGMITFNN---LCLKYVGVAFYNVGRSLTTVFNVLLSYLLLKQTTSFYAL 158

Query: 146 VSVFMLCAGVTL-VQWKPAQATKVVVEQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDT 204
           ++  ++  G  L V  + A+ T         LG     +A LC     +Y  KVL + D 
Sbjct: 159 LTCGIIIGGFWLGVDQEGAEGTL------SWLGTVFGVLASLCVSLNAIYTTKVLPAVDG 212

Query: 205 SLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYGYTYYVWFVIFLASVGGL----YT 260
           S+W       ++  I+ L  + L    +        G  ++ W ++ L  + G      T
Sbjct: 213 SIWRLTFYNNVNACILFLPLLLLLGELQALRDFAQLGSAHF-WGMMTLGGLFGFAIGYVT 271

Query: 261 SVVVKYTDNIMKGFSAAAAIVLSTIASVMLF 291
            + +K+T  +    S  A     T+ +V+ +
Sbjct: 272 GLQIKFTSPLTHNVSGTAKACAQTVLAVLYY 302


>gi|223671917 GDP-fucose transporter 1 isoform b [Homo sapiens]
          Length = 351

 Score = 37.4 bits (85), Expect = 0.019
 Identities = 48/211 (22%), Positives = 83/211 (39%), Gaps = 15/211 (7%)

Query: 86  KELLKLSVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQW 145
           + +L LSV  +     NN   L L  +  A Y V   L      L + L+L +T S    
Sbjct: 102 RSVLPLSVVFIGMITFNN---LCLKYVGVAFYNVGRSLTTVFNVLLSYLLLKQTTSFYAL 158

Query: 146 VSVFMLCAGVTL-VQWKPAQATKVVVEQNPLLGFGAIAIAVLCSGFAGVYFEKVLKSSDT 204
           ++  ++  G  L V  + A+ T         LG     +A LC     +Y  KVL + D 
Sbjct: 159 LTCGIIIGGFWLGVDQEGAEGTL------SWLGTVFGVLASLCVSLNAIYTTKVLPAVDG 212

Query: 205 SLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYGYTYYVWFVIFLASVGGL----YT 260
           S+W       ++  I+ L  + L    +        G  ++ W ++ L  + G      T
Sbjct: 213 SIWRLTFYNNVNACILFLPLLLLLGELQALRDFAQLGSAHF-WGMMTLGGLFGFAIGYVT 271

Query: 261 SVVVKYTDNIMKGFSAAAAIVLSTIASVMLF 291
            + +K+T  +    S  A     T+ +V+ +
Sbjct: 272 GLQIKFTSPLTHNVSGTAKACAQTVLAVLYY 302


>gi|14249528 solute carrier family 35, member B4 [Homo sapiens]
          Length = 331

 Score = 35.4 bits (80), Expect = 0.073
 Identities = 55/258 (21%), Positives = 107/258 (41%), Gaps = 43/258 (16%)

Query: 92  SVPSLVYAVQNNMAFL-------ALS-NLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKL 143
           ++P   YA+   M F        AL+ N+   ++ +     +    +  +++L +  S  
Sbjct: 60  AIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIF 119

Query: 144 QWVSVFMLCAGVTLVQWKPAQ--ATKVVVEQNP--------LLGFGAIAIAVLCSGFAGV 193
           ++ S+ ++  G+ +  +  A+   ++  + +N         LLG GA+  A+L S   G+
Sbjct: 120 KYTSIALVSVGIFICTFMSAKQVTSQSSLSENDGFQAFVWWLLGIGALTFALLMSARMGI 179

Query: 194 Y----FEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFY-----GYTY 244
           +    +++  K S  +L+  N  + L G +   + +Y  D A +  K   Y     G T 
Sbjct: 180 FQETLYKRFGKHSKEALFY-NHALPLPGFVFLASDIY--DHAVLFNKSELYEIPVIGVTL 236

Query: 245 -YVWFVIFLASVGGLYTSVVVKYTDNIMKGFSAAAAIVL--------STIASVMLFGLQI 295
             +WF + +     + T  V      I+    A+  + L        S I S++ F    
Sbjct: 237 PIMWFYLLM----NIITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPF 292

Query: 296 TLTFALGTLLVCVSIYLY 313
           TL   LGTL V +   +Y
Sbjct: 293 TLWHWLGTLFVFIGTLMY 310


>gi|31542711 ANT2-binding protein [Homo sapiens]
          Length = 371

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 18/65 (27%), Positives = 32/65 (49%)

Query: 94  PSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCA 153
           P+L      ++ ++AL+   A+ +Q+     I  T L +V  L R L   QW+ +    A
Sbjct: 94  PALCDMTGTSLMYVALNMTSASSFQMLRGAVIIFTGLFSVAFLGRRLVLSQWLGILATIA 153

Query: 154 GVTLV 158
           G+ +V
Sbjct: 154 GLVVV 158


>gi|5032213 solute carrier family 35, member B1 [Homo sapiens]
          Length = 322

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 39/188 (20%), Positives = 80/188 (42%), Gaps = 9/188 (4%)

Query: 130 LCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVVVEQNPLLGFG--AIAIAVLC 187
           L  V +L +     +++ V ++ AGV L  +KP    KVV  +   +G+G   + +++  
Sbjct: 126 LLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKP---KKVVGIEEHTVGYGELLLLLSLTL 182

Query: 188 SGFAGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLAGVYLSDGAEIKEKGFFYGYTYYVW 247
            G  GV  + +     T      + + L   ++   G+ L  G   +   F   Y   ++
Sbjct: 183 DGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGMGI-LFTGELWEFLSFAERYPAIIY 241

Query: 248 FVIFL---ASVGGLYTSVVVKYTDNIMKGFSAAAAIVLSTIASVMLFGLQITLTFALGTL 304
            ++     +++G  +  + V Y   +            + +ASV+LF   I+    +GT+
Sbjct: 242 NILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGTV 301

Query: 305 LVCVSIYL 312
           LV + + L
Sbjct: 302 LVFLGLGL 309


>gi|76159293 thioesterase superfamily member 4 [Homo sapiens]
          Length = 240

 Score = 31.2 bits (69), Expect = 1.4
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 6/85 (7%)

Query: 92  SVPSLVYAVQNNMAFLALSNLDAAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVSVFML 151
           ++ +++ A     A +A   +  A   + Y+  IP   LC+V+M+N  L K++    F+ 
Sbjct: 155 AIATMIDATVGMCAMMAGGIVMTANLNINYKRPIP---LCSVVMINSQLDKVEGRKFFVS 211

Query: 152 CAGVTLVQWKP--AQATKVVVEQNP 174
           C  V  V  K   ++AT + ++ NP
Sbjct: 212 C-NVQSVDEKTLYSEATSLFIKLNP 235


>gi|238814322 aldehyde dehydrogenase 1 family, member L2 [Homo
           sapiens]
          Length = 923

 Score = 30.8 bits (68), Expect = 1.8
 Identities = 28/80 (35%), Positives = 34/80 (42%), Gaps = 7/80 (8%)

Query: 119 VTYQLKIPCTALCTVLMLNRTLSKLQWVSVFMLCAGVTLVQWKPAQATKVV----VEQNP 174
           +T+  K P      ++  N  L  L W S   L AG TLV  KPAQ T +      E + 
Sbjct: 577 LTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLV-LKPAQVTPLTALKFAELSV 635

Query: 175 LLGF--GAIAIAVLCSGFAG 192
             GF  G I I     G AG
Sbjct: 636 KAGFPKGVINIIPGSGGIAG 655


>gi|21536378 ATP-binding cassette, sub-family B (MDR/TAP), member 11
           [Homo sapiens]
          Length = 1321

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 28/109 (25%)

Query: 160 WKPAQATKVVVEQNPLLGFGAIAIAVLCSGF----------AGVYFEKVLKSSDTSLWV- 208
           WK    T V++  +PL+G GA  I +  S F          AGV  ++V+ S  T     
Sbjct: 239 WK---LTLVIISVSPLIGIGAATIGLSVSKFTDYELKAYAKAGVVADEVISSMRTVAAFG 295

Query: 209 ---RNIQMYLSGIIVTLA-GVYLSDGAEIKEKGFFYG-YTYYVWFVIFL 252
              R ++ Y   ++     G+          KG   G +T +VW +IFL
Sbjct: 296 GEKREVERYEKNLVFAQRWGI---------RKGIVMGFFTGFVWCLIFL 335


>gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo
           sapiens]
          Length = 754

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 29/153 (18%), Positives = 60/153 (39%), Gaps = 22/153 (14%)

Query: 87  ELLKLSVPSL---VYAVQNNMAFLALSNLDAAVYQVTYQLKIPCT---ALCTVLMLNRTL 140
           +L ++ +P++   ++    N++ +   N     Y    ++ +P T   +    L+ N  L
Sbjct: 359 DLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNIL 418

Query: 141 SKLQWVSVFMLCAGVTLV----------QWKPAQATKVVVEQNPLLGFGAIAIAVLCSGF 190
               WV  F+ C G   V              A + K++   + L+G     + +    +
Sbjct: 419 RIFVWVIAFITCFGNLFVIGMRSFIKAENTTHAMSIKILCCADCLMGVYLFFVGIFDIKY 478

Query: 191 AGVYFEKVLKSSDTSLWVRNIQMYLSGIIVTLA 223
            G Y +  L      LW+ ++Q  L G +  L+
Sbjct: 479 RGQYQKYAL------LWMESVQCRLMGFLAMLS 505


>gi|196123580 NADH dehydrogenase subunit 2 [Homo sapiens
           neanderthalensis]
          Length = 347

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 54  IKLLLSVGILAKETGSLGRFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLD 113
           + LLL++ IL+   GS G    +    +L     +  +     V     NM  L L+   
Sbjct: 151 VSLLLTLSILSIMAGSWGGLNQTQLRKILAY-SSITHMGWMMAVLPYNPNMTILNLTIY- 208

Query: 114 AAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVS 147
             +   T  L +   +  T L+L+RT +KL W++
Sbjct: 209 -IILTTTAFLLLNLNSSTTTLLLSRTWNKLTWLT 241


>gi|251831108 NADH dehydrogenase subunit 2 [Homo sapiens]
          Length = 347

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 54  IKLLLSVGILAKETGSLGRFKASLRENVLGSPKELLKLSVPSLVYAVQNNMAFLALSNLD 113
           + LLL++ IL+   GS G    +    +L     +  +     V     NM  L L+   
Sbjct: 151 VSLLLTLSILSIMAGSWGGLNQTQLRKILAY-SSITHMGWMMAVLPYNPNMTILNLTIY- 208

Query: 114 AAVYQVTYQLKIPCTALCTVLMLNRTLSKLQWVS 147
             +   T  L +   +  T L+L+RT +KL W++
Sbjct: 209 -IILTTTAFLLLNLNSSTTTLLLSRTWNKLTWLT 241


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.137    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,192,830
Number of Sequences: 37866
Number of extensions: 368590
Number of successful extensions: 1018
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 996
Number of HSP's gapped (non-prelim): 21
length of query: 337
length of database: 18,247,518
effective HSP length: 103
effective length of query: 234
effective length of database: 14,347,320
effective search space: 3357272880
effective search space used: 3357272880
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.