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Search of human proteins with 54111428
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54111428 WD repeat domain, phosphoinositide interacting 2
isoform b [Homo sapiens]
(436 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54111428 WD repeat domain, phosphoinositide interacting 2 iso... 873 0.0
gi|7661580 WD repeat domain, phosphoinositide interacting 2 isof... 862 0.0
gi|75677331 WD repeat domain, phosphoinositide interacting 2 iso... 842 0.0
gi|75677329 WD repeat domain, phosphoinositide interacting 2 iso... 831 0.0
gi|75677340 WD repeat domain, phosphoinositide interacting 2 iso... 740 0.0
gi|157388939 WD repeat domain, phosphoinositide interacting 1 [H... 484 e-137
gi|122939167 WDR45-like [Homo sapiens] 140 2e-33
gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens] 101 2e-21
gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens] 100 3e-21
gi|21071067 TBP-associated factor 5 [Homo sapiens] 50 4e-06
gi|186928847 cirhin [Homo sapiens] 42 0.001
gi|32189425 WD repeat domain 69 [Homo sapiens] 40 0.004
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 38 0.016
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 38 0.021
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 38 0.021
gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Ho... 37 0.027
gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Ho... 37 0.027
gi|26665869 WD repeat domain 51B [Homo sapiens] 35 0.13
gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1... 34 0.23
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 34 0.23
gi|14150171 THO complex 3 [Homo sapiens] 34 0.23
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 33 0.51
gi|13376840 WD repeat domain 61 [Homo sapiens] 33 0.66
gi|148528998 Dmx-like 1 [Homo sapiens] 33 0.66
gi|157739942 gemin 5 [Homo sapiens] 32 0.87
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 32 0.87
gi|38569484 kinesin family member 21A [Homo sapiens] 32 1.5
gi|56550086 WD repeat and HMG-box DNA binding protein 1 isoform ... 32 1.5
gi|94400919 WD repeat domain 90 [Homo sapiens] 32 1.5
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] 31 1.9
>gi|54111428 WD repeat domain, phosphoinositide interacting 2
isoform b [Homo sapiens]
Length = 436
Score = 873 bits (2256), Expect = 0.0
Identities = 436/436 (100%), Positives = 436/436 (100%)
Query: 1 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI 60
MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI
Sbjct: 1 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI 60
Query: 61 VERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLY 120
VERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLY
Sbjct: 61 VERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLY 120
Query: 121 IHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMI 180
IHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMI
Sbjct: 121 IHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMI 180
Query: 181 PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSM 240
PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSM
Sbjct: 181 PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSM 240
Query: 241 DGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGR 300
DGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGR
Sbjct: 241 DGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGR 300
Query: 301 AFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGS 360
AFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGS
Sbjct: 301 AFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGS 360
Query: 361 LETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASAL 420
LETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASAL
Sbjct: 361 LETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASAL 420
Query: 421 RLDEDSEHPPMILRTD 436
RLDEDSEHPPMILRTD
Sbjct: 421 RLDEDSEHPPMILRTD 436
>gi|7661580 WD repeat domain, phosphoinositide interacting 2 isoform
a [Homo sapiens]
Length = 454
Score = 862 bits (2227), Expect = 0.0
Identities = 436/454 (96%), Positives = 436/454 (96%), Gaps = 18/454 (3%)
Query: 1 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS 42
MNLASQSGEAGAGQLLFANFNQDNT SLAVGSKSGYKFFSLSS
Sbjct: 1 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 60
Query: 43 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 102
VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
Sbjct: 61 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 120
Query: 103 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 162
AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
Sbjct: 121 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 180
Query: 163 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 222
IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
Sbjct: 181 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 240
Query: 223 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 282
FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
Sbjct: 241 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 300
Query: 283 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 342
ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
Sbjct: 301 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360
Query: 343 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 402
PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
Sbjct: 361 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 420
Query: 403 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 436
DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
Sbjct: 421 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 454
>gi|75677331 WD repeat domain, phosphoinositide interacting 2
isoform d [Homo sapiens]
Length = 425
Score = 842 bits (2176), Expect = 0.0
Identities = 425/436 (97%), Positives = 425/436 (97%), Gaps = 11/436 (2%)
Query: 1 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI 60
MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI
Sbjct: 1 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI 60
Query: 61 VERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLY 120
VERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLY
Sbjct: 61 VERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLY 120
Query: 121 IHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMI 180
IHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMI
Sbjct: 121 IHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMI 180
Query: 181 PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSM 240
PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSM
Sbjct: 181 PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSM 240
Query: 241 DGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGR 300
DGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGR
Sbjct: 241 DGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGR 300
Query: 301 AFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGS 360
AFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGS
Sbjct: 301 AFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGS 360
Query: 361 LETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASAL 420
LETTNEILDSASHDCPLVTQTYGAAAGK AYTDDLGAVGGACLEDEASAL
Sbjct: 361 LETTNEILDSASHDCPLVTQTYGAAAGK-----------AYTDDLGAVGGACLEDEASAL 409
Query: 421 RLDEDSEHPPMILRTD 436
RLDEDSEHPPMILRTD
Sbjct: 410 RLDEDSEHPPMILRTD 425
>gi|75677329 WD repeat domain, phosphoinositide interacting 2
isoform c [Homo sapiens]
Length = 443
Score = 831 bits (2147), Expect = 0.0
Identities = 425/454 (93%), Positives = 425/454 (93%), Gaps = 29/454 (6%)
Query: 1 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS 42
MNLASQSGEAGAGQLLFANFNQDNT SLAVGSKSGYKFFSLSS
Sbjct: 1 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS 60
Query: 43 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 102
VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
Sbjct: 61 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL 120
Query: 103 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 162
AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
Sbjct: 121 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT 180
Query: 163 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 222
IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
Sbjct: 181 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE 240
Query: 223 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 282
FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
Sbjct: 241 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM 300
Query: 283 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 342
ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
Sbjct: 301 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 360
Query: 343 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT 402
PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK AYT
Sbjct: 361 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT 409
Query: 403 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 436
DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
Sbjct: 410 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD 443
>gi|75677340 WD repeat domain, phosphoinositide interacting 2
isoform e [Homo sapiens]
Length = 384
Score = 740 bits (1910), Expect = 0.0
Identities = 372/383 (97%), Positives = 372/383 (97%), Gaps = 11/383 (2%)
Query: 54 DTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIV 113
DTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIV
Sbjct: 13 DTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIV 72
Query: 114 CLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTIN 173
CLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTIN
Sbjct: 73 CLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTIN 132
Query: 174 LRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSI 233
LRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSI
Sbjct: 133 LRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSI 192
Query: 234 CSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVT 293
CSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVT
Sbjct: 193 CSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVT 252
Query: 294 EMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMK 353
EMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMK
Sbjct: 253 EMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMK 312
Query: 354 QHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACL 413
QHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK AYTDDLGAVGGACL
Sbjct: 313 QHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYTDDLGAVGGACL 361
Query: 414 EDEASALRLDEDSEHPPMILRTD 436
EDEASALRLDEDSEHPPMILRTD
Sbjct: 362 EDEASALRLDEDSEHPPMILRTD 384
>gi|157388939 WD repeat domain, phosphoinositide interacting 1 [Homo
sapiens]
Length = 446
Score = 484 bits (1245), Expect = e-137
Identities = 247/418 (59%), Positives = 320/418 (76%), Gaps = 7/418 (1%)
Query: 19 NFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAP 78
+FNQD TSLA G+K+GYK FSLSSV++L+Q++ + DV IVERLFSSSLV +VS P
Sbjct: 21 SFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEIPDVYIVERLFSSSLVVVVSHTKP 80
Query: 79 RKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPP 138
R++ V HFKKGTEICNYSYS+ IL+++LNRQRL+VCLEES+YIHNI+DMK+L T+ + P
Sbjct: 81 RQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCLEESIYIHNIKDMKLLKTLLDIPA 140
Query: 139 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 198
NP GLCALSIN+ N YLAYPGS T GE+ ++D +L+ I AH+ LAA+ F+ASG+K
Sbjct: 141 NPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLKTVCTIAAHEGTLAAITFNASGSK 200
Query: 199 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 258
LA+ASEKGTVIRVFS+P+GQKL+EFRRG+KR V+I SL FSMD FL ASSNTETVHIFK
Sbjct: 201 LASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISSLVFSMDSQFLCASSNTETVHIFK 260
Query: 259 LETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSL 318
LE V PEEP+TW+GY GK+ MA+T+YLP+QV++M +Q RAFAT RL F G +NIC+L
Sbjct: 261 LEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDMMHQDRAFATARLNFSGQRNICTL 320
Query: 319 ATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLV 378
+TIQK+PRLLV ++ G+LYMYNLDPQ+GGEC L+K H L GS TT E ++ P +
Sbjct: 321 STIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTHSLLGS-GTTEENKENDLR--PSL 377
Query: 379 TQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASA---LRLDEDSEHPPMIL 433
Q+Y A + + S+ T Y++D GA+ G + + A + LD+++E PP+IL
Sbjct: 378 PQSYAATVARPS-ASSASTVPGYSEDGGALRGEVIPEHEFATGPVCLDDENEFPPIIL 434
>gi|122939167 WDR45-like [Homo sapiens]
Length = 344
Score = 140 bits (353), Expect = 2e-33
Identities = 109/345 (31%), Positives = 172/345 (49%), Gaps = 39/345 (11%)
Query: 15 LLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVS 74
LL+A FNQD+ A G ++G++ ++ + + E+ E + V VE LF + +A+V
Sbjct: 13 LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGHVEMLFRCNYLALVG 70
Query: 75 -----LKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESL----YIHNIR 125
P K+ + K + +S + AVKL R R++V L+ + + HN
Sbjct: 71 GGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPH 130
Query: 126 DMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANM-IPAHD 184
+ V ET NP GLC L N++N LA+PG+ T G VQ+ D + + IPAH+
Sbjct: 131 QLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDLASTEKPPVDIPAHE 185
Query: 185 SPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMF 244
L+ +A + GT++ATASEKGT+IR+F G + E RRG + +I + F+ D
Sbjct: 186 GVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG-SQAANIYCINFNQDASL 244
Query: 245 LSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFAT 304
+ SS+ TVHIF E K +AS S+LP + F+ +F+
Sbjct: 245 ICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP----KYFSSKWSFSK 288
Query: 305 VRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGEC 349
++P G IC+ T + ++ ADG Y + +P+ GEC
Sbjct: 289 FQVP-SGSPCICAFGT--EPNAVIAICADGSYYKFLFNPK--GEC 328
>gi|71483646 WD repeat domain 45 isoform 2 [Homo sapiens]
Length = 360
Score = 101 bits (251), Expect = 2e-21
Identities = 70/260 (26%), Positives = 127/260 (48%), Gaps = 19/260 (7%)
Query: 20 FNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPR 79
FNQD + ++G + +++ + + + + + +VE L S+L+A+V +
Sbjct: 14 FNQDQSCFCCAMETGVRIYNVEPLMEKGHL-DHEQVGSMGLVEMLHRSNLLALVGGGSSP 72
Query: 80 KLKVCHF-----------KKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMK 128
K K + ++++ +L+V++ ++++ L+ +Y+++ D
Sbjct: 73 KFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDNP 132
Query: 129 VLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPAH 183
+T NP GLC L + + L +PG G +Q+ D + + A I AH
Sbjct: 133 RKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINAH 191
Query: 184 DSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGM 243
S +A ++ + GT +A+AS+KGT+IR+F +KL E RRG C + FS D
Sbjct: 192 QSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDSS 250
Query: 244 FLSASSNTETVHIFKLETVK 263
FL ASS+ TVHIF L+ +
Sbjct: 251 FLCASSDKGTVHIFALKDTR 270
>gi|47059042 WD repeat domain 45 isoform 1 [Homo sapiens]
Length = 361
Score = 100 bits (249), Expect = 3e-21
Identities = 70/261 (26%), Positives = 127/261 (48%), Gaps = 20/261 (7%)
Query: 20 FNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPR 79
FNQD + ++G + +++ + + + + + +VE L S+L+A+V +
Sbjct: 14 FNQDQSCFCCAMETGVRIYNVEPLMEKGHL-DHEQVGSMGLVEMLHRSNLLALVGGGSSP 72
Query: 80 KLKVCHF------------KKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDM 127
K K + ++++ +L+V++ ++++ L+ +Y+++ D
Sbjct: 73 KFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIVIVLKNRIYVYSFPDN 132
Query: 128 KVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR-----AANMIPA 182
+T NP GLC L + + L +PG G +Q+ D + + A I A
Sbjct: 133 PRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKC-GSLQLVDLASTKPGTSSAPFTINA 191
Query: 183 HDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDG 242
H S +A ++ + GT +A+AS+KGT+IR+F +KL E RRG C + FS D
Sbjct: 192 HQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGTDPATLYC-INFSHDS 250
Query: 243 MFLSASSNTETVHIFKLETVK 263
FL ASS+ TVHIF L+ +
Sbjct: 251 SFLCASSDKGTVHIFALKDTR 271
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 50.1 bits (118), Expect = 4e-06
Identities = 37/144 (25%), Positives = 69/144 (47%), Gaps = 11/144 (7%)
Query: 140 PAGLCALSINNDNCYLAYPGSATIGE------VQVFDTINLRAANMIPAHDSPLAALAFD 193
P + A + + NC +P S + V+++D +N + H P+ +L F
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFS 678
Query: 194 ASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTET 253
+G LAT + G V+ ++ I G + E + ++CSL FS DG L++ S T
Sbjct: 679 PNGRFLATGATDGRVL-LWDIGHGLMVGELKGHTD---TVCSLRFSRDGEILASGSMDNT 734
Query: 254 VHIF-KLETVKEKPPEEPTTWTGY 276
V ++ ++ ++ ++ TT TG+
Sbjct: 735 VRLWDAIKAFEDLETDDFTTATGH 758
>gi|186928847 cirhin [Homo sapiens]
Length = 686
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 3/96 (3%)
Query: 170 DTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG--QKLFEFRRGV 227
D I+L+ + +PA + F TKL AS +G + + + G + L F+
Sbjct: 423 DNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGA-LHIVQLSGGSFKHLHAFQPQS 481
Query: 228 KRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK 263
++C LA S DG +L+AS + VH++ ++ +K
Sbjct: 482 GTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLK 517
Score = 37.0 bits (84), Expect = 0.035
Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 13/147 (8%)
Query: 73 VSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRL-IVCLEESLYIHNIRDMKVLH 131
+SLK K+ F + +S +T L V N+ L IV L + H LH
Sbjct: 425 ISLKRVSKMPA--FLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKH-------LH 475
Query: 132 TIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALA 191
+ +C L+++ D +LA S T V V++ L+ +PA++ P+ A+A
Sbjct: 476 AFQPQSGTVEAMCLLAVSPDGNWLA--ASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMA 533
Query: 192 FDASGTKLATASEKGTVIRVFSIPEGQ 218
+ L A V +SIP+ Q
Sbjct: 534 IAPNTNNLVIAHSDQQVFE-YSIPDKQ 559
Score = 31.2 bits (69), Expect = 1.9
Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 164 GEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEF 223
GE+ +D L + A P+ ++A SG++L E G+V ++F I + FE
Sbjct: 81 GEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSV-KLFQITPDKIQFE- 138
Query: 224 RRGVKRCVSICSLAFSMDGMFLSASS 249
R ++ I SL++ G ++A S
Sbjct: 139 RNFDRQKSRILSLSWHPSGTHIAAGS 164
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 40.0 bits (92), Expect = 0.004
Identities = 58/260 (22%), Positives = 104/260 (40%), Gaps = 36/260 (13%)
Query: 116 EESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR 175
+++ + ++ K HT R + A + LS N + +A T ++ +D N
Sbjct: 156 DKTCKLWSVETGKCYHTFRG---HTAEIVCLSFNPQSTLVATGSMDTTAKL--WDIQNGE 210
Query: 176 AANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICS 235
+ H + + +L+F+ SG ++ T S TV+ V+ G+K+ + C I S
Sbjct: 211 EVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVV-VWDADTGRKVNIL---IGHCAEISS 266
Query: 236 LAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEM 295
+F+ D + S +T ++ K T TG+ ++L + Y
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGK-----CVATLTGHDDEILDSCFDY-------- 313
Query: 296 FNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQH 355
G+ AT G I S AT + I +L +G + + +PQ H
Sbjct: 314 --TGKLIATASAD--GTARIFSAATRKCIAKL--EGHEGEISKISFNPQ--------GNH 359
Query: 356 RLDGSLETTNEILDSASHDC 375
L GS + T I D+ + C
Sbjct: 360 LLTGSSDKTARIWDAQTGQC 379
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 38.1 bits (87), Expect = 0.016
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 22/151 (14%)
Query: 139 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 198
+P+G C + DN V+V+D R H + + L+F SG
Sbjct: 196 HPSGTCIAAAGMDNT------------VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNY 243
Query: 199 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 258
L TAS T +++ + EG+ L+ ++ AFS G + ++ + E V ++K
Sbjct: 244 LITASSDST-LKILDLMEGRLLYTLHGHQGPATTV---AFSRTGEYFASGGSDEQVMVWK 299
Query: 259 --LETVKE----KPPEEPTTWTGYFGKVLMA 283
+ V K P P T G + ++
Sbjct: 300 SNFDIVDHGEVTKVPRPPATLASSMGNLTVS 330
Score = 28.9 bits (63), Expect = 9.6
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 8/78 (10%)
Query: 182 AHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVK--RCVSICSLAFS 239
AH + + ++ F + G TAS+ TV +V++ + LF + + RC FS
Sbjct: 101 AHTATVRSVHFCSDGQSFVTASDDKTV-KVWATHRQKFLFSLSQHINWVRCAK-----FS 154
Query: 240 MDGMFLSASSNTETVHIF 257
DG + ++S+ +TV ++
Sbjct: 155 PDGRLIVSASDDKTVKLW 172
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 37.7 bits (86), Expect = 0.021
Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 16/120 (13%)
Query: 139 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 198
+P+G C + DN V+V+D R H + + L+F SG
Sbjct: 158 HPSGTCIAAAGMDNT------------VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNY 205
Query: 199 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 258
L TAS T +++ + EG+ L+ ++ AFS G + ++ + E V ++K
Sbjct: 206 LITASSDST-LKILDLMEGRLLYTLHGHQGPATTV---AFSRTGEYFASGGSDEQVMVWK 261
Score = 28.9 bits (63), Expect = 9.6
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 8/78 (10%)
Query: 182 AHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVK--RCVSICSLAFS 239
AH + + ++ F + G TAS+ TV +V++ + LF + + RC FS
Sbjct: 63 AHTATVRSVHFCSDGQSFVTASDDKTV-KVWATHRQKFLFSLSQHINWVRCAK-----FS 116
Query: 240 MDGMFLSASSNTETVHIF 257
DG + ++S+ +TV ++
Sbjct: 117 PDGRLIVSASDDKTVKLW 134
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 37.7 bits (86), Expect = 0.021
Identities = 29/120 (24%), Positives = 51/120 (42%), Gaps = 16/120 (13%)
Query: 139 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 198
+P+G C + DN V+V+D R H + + L+F SG
Sbjct: 196 HPSGTCIAAAGMDNT------------VKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNY 243
Query: 199 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 258
L TAS T +++ + EG+ L+ ++ AFS G + ++ + E V ++K
Sbjct: 244 LITASSDST-LKILDLMEGRLLYTLHGHQGPATTV---AFSRTGEYFASGGSDEQVMVWK 299
Score = 28.9 bits (63), Expect = 9.6
Identities = 21/78 (26%), Positives = 40/78 (51%), Gaps = 8/78 (10%)
Query: 182 AHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVK--RCVSICSLAFS 239
AH + + ++ F + G TAS+ TV +V++ + LF + + RC FS
Sbjct: 101 AHTATVRSVHFCSDGQSFVTASDDKTV-KVWATHRQKFLFSLSQHINWVRCAK-----FS 154
Query: 240 MDGMFLSASSNTETVHIF 257
DG + ++S+ +TV ++
Sbjct: 155 PDGRLIVSASDDKTVKLW 172
>gi|153218631 breast carcinoma amplified sequence 3 isoform 1 [Homo
sapiens]
Length = 928
Score = 37.4 bits (85), Expect = 0.027
Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 13/117 (11%)
Query: 162 TIGEVQVFDTINLRAANMI---PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG- 217
T+GE QV + + + ++ PAH+ P+ +AF+ SG L T G VF I
Sbjct: 326 TVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHP 385
Query: 218 --------QKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKP 266
L+ RG + + FS D ++ S+ T H+F + +P
Sbjct: 386 WSSSQCAVHHLYTLHRGETE-AKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQP 441
>gi|153218595 breast carcinoma amplified sequence 3 isoform 2 [Homo
sapiens]
Length = 913
Score = 37.4 bits (85), Expect = 0.027
Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 13/117 (11%)
Query: 162 TIGEVQVFDTINLRAANMI---PAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG- 217
T+GE QV + + + ++ PAH+ P+ +AF+ SG L T G VF I
Sbjct: 326 TVGEGQVLVSEDSDSDGIVAHFPAHEKPVCCMAFNTSGMLLVTTDTLGHDFHVFQILTHP 385
Query: 218 --------QKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKP 266
L+ RG + + FS D ++ S+ T H+F + +P
Sbjct: 386 WSSSQCAVHHLYTLHRGETE-AKVQDICFSHDCRWVVVSTLRGTSHVFPINPYGGQP 441
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 35.0 bits (79), Expect = 0.13
Identities = 26/78 (33%), Positives = 41/78 (52%), Gaps = 8/78 (10%)
Query: 182 AHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVK--RCVSICSLAFS 239
AH +P+ ++ F A G LATASE + I+V+S+ + L+ R RC FS
Sbjct: 100 AHTAPVRSVDFSADGQFLATASEDKS-IKVWSMYRQRFLYSLYRHTHWVRCAK-----FS 153
Query: 240 MDGMFLSASSNTETVHIF 257
DG + + S +T+ I+
Sbjct: 154 PDGRLIVSCSEDKTIKIW 171
Score = 33.9 bits (76), Expect = 0.30
Identities = 27/117 (23%), Positives = 52/117 (44%), Gaps = 17/117 (14%)
Query: 139 NPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTK 198
NP+G C S +D V+V+D + H + ++F SG
Sbjct: 195 NPSGTCIASAGSDQT------------VKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNY 242
Query: 199 LATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDG-MFLSASSNTETV 254
L TAS GT +++ + EG+ ++ + + +++FS G +F S ++T+ +
Sbjct: 243 LITASSDGT-LKILDLLEGRLIYTLQ---GHTGPVFTVSFSKGGELFASGGADTQVL 295
Score = 32.3 bits (72), Expect = 0.87
Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 183 HDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDG 242
H + ++ F G LA+AS TV R++ + K EF+ + S+ FS DG
Sbjct: 59 HKDVVTSVQFSPHGNLLASASRDRTV-RLWIPDKRGKFSEFKA---HTAPVRSVDFSADG 114
Query: 243 MFLSASSNTETVHIFKL 259
FL+ +S +++ ++ +
Sbjct: 115 QFLATASEDKSIKVWSM 131
>gi|5901892 WD repeat and HMG-box DNA binding protein 1 isoform 1
[Homo sapiens]
Length = 1129
Score = 34.3 bits (77), Expect = 0.23
Identities = 28/101 (27%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
Query: 166 VQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE-----GQKL 220
V++ D ++ HD+P+ +L+FD LA+AS G+V RV+ I + L
Sbjct: 118 VKIVDVMDSSQQKTFRGHDAPVLSLSFDPKDIFLASASCDGSV-RVWQISDQTCAISWPL 176
Query: 221 FEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET 261
+ V SIC LA+ L A ++V +++ E+
Sbjct: 177 LQKCNDVINAKSICRLAWQPKSGKLLAIPVEKSVKLYRRES 217
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 34.3 bits (77), Expect = 0.23
Identities = 24/102 (23%), Positives = 48/102 (47%), Gaps = 6/102 (5%)
Query: 159 GSATI-GEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEG 217
G+ T+ +++++D P H P+ ++AF +G LATA++ +V + +
Sbjct: 366 GTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSV----KLWDL 421
Query: 218 QKLFEFRR-GVKRCVSICSLAFSMDGMFLSASSNTETVHIFK 258
+KL F+ + + SL F G +L+ ++I K
Sbjct: 422 RKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICK 463
>gi|14150171 THO complex 3 [Homo sapiens]
Length = 351
Score = 34.3 bits (77), Expect = 0.23
Identities = 32/117 (27%), Positives = 52/117 (44%), Gaps = 8/117 (6%)
Query: 146 LSINNDN-CYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASE 204
+S NNDN + G+ G + + L+ I AH S + FD G AT S
Sbjct: 188 ISWNNDNNMFFLTNGN---GCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSA 244
Query: 205 KGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET 261
V S+ + +L R + + +L+FS DG L+++S + I ++ET
Sbjct: 245 DALV----SLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVET 297
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 33.1 bits (74), Expect = 0.51
Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 184 DSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGM 243
D + + F LAT ++ G I+V+ I GQ L F R + + L+FS D
Sbjct: 264 DDAVLCMCFSRDTEMLATGAQDGK-IKVWKIQSGQCLRRFERAHSK--GVTCLSFSKDSS 320
Query: 244 FLSASSNTETVHIFKLETVK 263
+ ++S +T+ I L++ K
Sbjct: 321 QILSASFDQTIRIHGLKSGK 340
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 32.7 bits (73), Expect = 0.66
Identities = 25/119 (21%), Positives = 52/119 (43%), Gaps = 6/119 (5%)
Query: 143 LCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATA 202
+ +++ + D YLA A G + +FD + + + H P+ +L F L TA
Sbjct: 151 ILSIAYSPDGKYLA--SGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTA 208
Query: 203 SEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLET 261
S+ G I+++ + + ++AF D +SS+ ++V ++ + T
Sbjct: 209 SDDG-YIKIYDVQHANLAGTLS---GHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGT 263
Score = 32.0 bits (71), Expect = 1.1
Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 18/164 (10%)
Query: 187 LAALAFDASGT-KLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFL 245
L ++ D S T +A +S IR++ + G+++ G V +LAFS D +L
Sbjct: 65 LGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGP---VDAWTLAFSPDSQYL 121
Query: 246 SASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMA-----STSYLPSQVTEMFNQGR 300
+ ++ V+IF +E+ K++ + GK +++ YL S +
Sbjct: 122 ATGTHVGKVNIFGVESGKKEYSLDTR------GKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 301 AFATVRL--PFCGHKNICSLATIQKIPRLLVGAA-DGYLYMYNL 341
AT +L GH T +LLV A+ DGY+ +Y++
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDV 219
>gi|148528998 Dmx-like 1 [Homo sapiens]
Length = 3027
Score = 32.7 bits (73), Expect = 0.66
Identities = 33/141 (23%), Positives = 55/141 (39%), Gaps = 9/141 (6%)
Query: 74 SLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTI 133
S+ P CH K + S S+ I L+ VCL ++L +
Sbjct: 2826 SMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDNRNVCLWDTLVA------PANSLV 2879
Query: 134 RETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFD 193
+ +G L+ + L G G VFD + + +HDSP+ A+A D
Sbjct: 2880 HAFTCHDSGATVLAYAPKHQLLISGGRK--GFTYVFDLCQRQQRQLFQSHDSPVKAVAVD 2937
Query: 194 ASGTKLATASEKGTVIRVFSI 214
+ T S +G I+++S+
Sbjct: 2938 PTEEYFVTGSAEGN-IKIWSL 2957
>gi|157739942 gemin 5 [Homo sapiens]
Length = 1508
Score = 32.3 bits (72), Expect = 0.87
Identities = 32/125 (25%), Positives = 56/125 (44%), Gaps = 10/125 (8%)
Query: 180 IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSIC---SL 236
+P H +++ A G +A +E G+ I +F IP + + ++ K +I
Sbjct: 536 LPVHTE----ISWKADGKIMALGNEDGS-IEIFQIPNLKLICTIQQHHKLVNTISWHHEH 590
Query: 237 AFSMDGMFLSAS-SNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEM 295
+ +L AS SN +++ L+TV E PE P T T + + L T+ + S
Sbjct: 591 GSQPELSYLMASGSNNAVIYVHNLKTVIESSPESPVTITEPY-RTLSGHTAKITSVAWSP 649
Query: 296 FNQGR 300
+ GR
Sbjct: 650 HHDGR 654
>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit
[Homo sapiens]
Length = 340
Score = 32.3 bits (72), Expect = 0.87
Identities = 24/91 (26%), Positives = 40/91 (43%), Gaps = 2/91 (2%)
Query: 157 YPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE 216
+ A ++++D + H+S + A+AF +G T S+ T R+F +
Sbjct: 199 FVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDAT-CRLFDLRA 257
Query: 217 GQKLFEFRRGVKRCVSICSLAFSMDGMFLSA 247
Q+L + C I S+AFS G L A
Sbjct: 258 DQELLMYSHDNIIC-GITSVAFSRSGRLLLA 287
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 31.6 bits (70), Expect = 1.5
Identities = 56/277 (20%), Positives = 106/277 (38%), Gaps = 42/277 (15%)
Query: 79 RKLKVCHFKKGTEICNYS-YSNTILAVKLNRQRLIVCLEESLYIH--NIRDM-KVLHTIR 134
R KV + G EI + + N +++VK +V + YI +IRD K + T+
Sbjct: 1354 RTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLT 1413
Query: 135 ETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDA 194
+ G T+G+ T A IP+ ++ + +A +
Sbjct: 1414 SS----------------------GQVTLGDACSASTSRTVA---IPSGENQINQIALNP 1448
Query: 195 SGTKLATASEKGTVIRVFSIPEGQKLFEF--RRGVKRCVSICSLAFSMDGMFLSASSNTE 252
+GT L AS G +R++ + Q + G C+++ ++ D + S
Sbjct: 1449 TGTFLYAAS--GNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQD--LIITGSKDH 1504
Query: 253 TVHIFK-----LETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVT--EMFNQGRAFATV 305
+ +F L TV EP + G + + S+ + ++ +
Sbjct: 1505 YIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQ 1564
Query: 306 RLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD 342
++P +C+L + P LL G G L ++N+D
Sbjct: 1565 QVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMD 1601
>gi|56550086 WD repeat and HMG-box DNA binding protein 1 isoform 2
[Homo sapiens]
Length = 1006
Score = 31.6 bits (70), Expect = 1.5
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 183 HDSPLAALAFDASGTKLATASEKGTVIRVFSIPE-----GQKLFEFRRGVKRCVSICSLA 237
HD+P+ +L+FD LA+AS G+V RV+ I + L + V SIC LA
Sbjct: 12 HDAPVLSLSFDPKDIFLASASCDGSV-RVWQISDQTCAISWPLLQKCNDVINAKSICRLA 70
Query: 238 FSMDGMFLSASSNTETVHIFKLET 261
+ L A ++V +++ E+
Sbjct: 71 WQPKSGKLLAIPVEKSVKLYRRES 94
>gi|94400919 WD repeat domain 90 [Homo sapiens]
Length = 1748
Score = 31.6 bits (70), Expect = 1.5
Identities = 18/60 (30%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Query: 164 GEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEF 223
G + DT++ + +H +P+ ALA + +LAT S+ TV R++ + Q+L++F
Sbjct: 680 GHLGFLDTLSRVYHMLARSHTAPVLALAMEQRRGQLATVSQDRTV-RIWDLATLQQLYDF 738
>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
Length = 770
Score = 31.2 bits (69), Expect = 1.9
Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 8/98 (8%)
Query: 164 GEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEF 223
G + V+D N H + + GTKL T TV R + + EG++L +
Sbjct: 596 GNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTV-RSWDLREGRQLQQH 654
Query: 224 RRGVKRCVSICSLAFSMDGMFLSA---SSNTETVHIFK 258
I SL + G +L+ SSN E +H+ K
Sbjct: 655 ----DFTSQIFSLGYCPTGEWLAVGMESSNVEVLHVNK 688
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,784,681
Number of Sequences: 37866
Number of extensions: 721822
Number of successful extensions: 1668
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 1596
Number of HSP's gapped (non-prelim): 89
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.