Search of human proteins with 51477716

Search of human proteins with 51477716

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51477716 mannosidase, alpha, class 2A, member 2 [Homo
sapiens]
         (1150 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51477716 mannosidase, alpha, class 2A, member 2 [Homo sapiens]    2342   0.0  
gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo sapiens]    1241   0.0  
gi|51873064 mannosidase, alpha, class 2B, member 1 precursor [Ho...   287   4e-77
gi|50659093 mannosidase, alpha, class 2B, member 2 [Homo sapiens]     270   6e-72
gi|46852164 mannosidase, alpha, class 2C, member 1 [Homo sapiens]      45   3e-04
gi|116812628 coiled-coil domain containing 67 [Homo sapiens]           33   2.0  

>gi|51477716 mannosidase, alpha, class 2A, member 2 [Homo sapiens]
          Length = 1150

 Score = 2342 bits (6069), Expect = 0.0
 Identities = 1150/1150 (100%), Positives = 1150/1150 (100%)

Query: 1    MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPRSQISVLQNRIEQLEQL 60
            MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPRSQISVLQNRIEQLEQL
Sbjct: 1    MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPRSQISVLQNRIEQLEQL 60

Query: 61   LEENHEIISHIKDSVLELTANAEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFAL 120
            LEENHEIISHIKDSVLELTANAEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFAL
Sbjct: 61   LEENHEIISHIKDSVLELTANAEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFAL 120

Query: 121  GGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGW 180
            GGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGW
Sbjct: 121  GGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGW 180

Query: 181  IKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGN 240
            IKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGN
Sbjct: 181  IKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGN 240

Query: 241  GQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYL 300
            GQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYL
Sbjct: 241  GQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYL 300

Query: 301  LRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTC 360
            LRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTC
Sbjct: 301  LRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTC 360

Query: 361  GPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLL 420
            GPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLL
Sbjct: 361  GPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLL 420

Query: 421  VPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPG 480
            VPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPG
Sbjct: 421  VPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPG 480

Query: 481  ARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHAR 540
            ARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHAR
Sbjct: 481  ARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHAR 540

Query: 541  RSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVII 600
            RSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVII
Sbjct: 541  RSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVII 600

Query: 601  HAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLEQER 660
            HAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLEQER
Sbjct: 601  HAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLEQER 660

Query: 661  FSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQL 720
            FSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQL
Sbjct: 661  FSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQL 720

Query: 721  QLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGL 780
            QLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGL
Sbjct: 721  QLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGL 780

Query: 781  LKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPF 840
            LKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPF
Sbjct: 781  LKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPF 840

Query: 841  FSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFT 900
            FSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFT
Sbjct: 841  FSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFT 900

Query: 901  DLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVIL 960
            DLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVIL
Sbjct: 901  DLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVIL 960

Query: 961  DRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSMYLN 1020
            DRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSMYLN
Sbjct: 961  DRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSMYLN 1020

Query: 1021 APALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKG 1080
            APALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKG
Sbjct: 1021 APALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKG 1080

Query: 1081 FDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPM 1140
            FDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPM
Sbjct: 1081 FDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPM 1140

Query: 1141 EIATFRLRLG 1150
            EIATFRLRLG
Sbjct: 1141 EIATFRLRLG 1150


>gi|51477714 mannosidase, alpha, class 2A, member 1 [Homo sapiens]
          Length = 1144

 Score = 1241 bits (3211), Expect = 0.0
 Identities = 623/1155 (53%), Positives = 815/1155 (70%), Gaps = 18/1155 (1%)

Query: 1    MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHD-PTRHQNGGNFPRSQISVLQNRIEQLEQ 59
            MKL +Q TV G+AIFCV +FSLYLMLDR   D P   +  G+FP+ Q+S+LQ +I+ LE+
Sbjct: 1    MKLSRQFTVFGSAIFCVVIFSLYLMLDRGHLDYPRNPRREGSFPQGQLSMLQEKIDHLER 60

Query: 60   LLEENHEIISHIKDSVLELTANAE-GPPAMLPYYTVN-GSWVVPPEPRPSFFSISPQDCQ 117
            LL EN+EIIS+I+DSV+ L+ + E GP +    ++   GS ++P +      S+   DC 
Sbjct: 61   LLAENNEIISNIRDSVINLSESVEDGPKSSQSNFSQGAGSHLLPSQLS---LSVDTADCL 117

Query: 118  FALGGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHND 177
            FA        ++QML V   + FDN DGGVW+QGFDI+Y+ ++WD E LQVFVVPHSHND
Sbjct: 118  FASQSGSHNSDVQMLDVYSLISFDNPDGGVWKQGFDITYESNEWDTEPLQVFVVPHSHND 177

Query: 178  PGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRL 237
            PGW+KTF+ Y+ ++TQ+I N+MV KL+ED RR+F+W+E+S+ +KWWD I++QK+ AV+ L
Sbjct: 178  PGWLKTFNDYFRDKTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSL 237

Query: 238  VGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTM 297
            + NGQLEI TGGWVMPDEA  HYFALIDQLIEGHQWLE N+G  PRSGWA+DPFG+S TM
Sbjct: 238  IENGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLENNIGVKPRSGWAIDPFGHSPTM 297

Query: 298  PYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVP 357
             YLL RA L+ MLIQRVHYA+KKHFA   +LEF WRQ WD  S TDI CHMMPFYSYD+P
Sbjct: 298  AYLLNRAGLSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVTDILCHMMPFYSYDIP 357

Query: 358  HTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSN 417
            HTCGPDPKICCQFDFKRLPGGR  CPW VPP  I   NV  RA +LLDQYRKKS+LFR+ 
Sbjct: 358  HTCGPDPKICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTK 417

Query: 418  VLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGV 477
            VLL PLGDDFRY +  EWD QF NYQ+LFD+ NS+    V+ QFGTLSD+FDAL K    
Sbjct: 418  VLLAPLGDDFRYCEYTEWDLQFKNYQQLFDYMNSQSKFKVKIQFGTLSDFFDALDKADET 477

Query: 478  EPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAA 537
            +       FPVLSGDFF+YADR+DHYW+GY+TSRPFYK +DR++E+HLR AE+LY  A  
Sbjct: 478  QRDKGQSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALR 537

Query: 538  HARRSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQ 597
             A +  +      S +T LTEARR LGLFQHHDAITGTAK+ VVVDYG RL  SL+ L++
Sbjct: 538  QAHKYKINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMVLEK 597

Query: 598  VIIHAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRFVVLFNPLE 657
            +I ++A  L+L DK TY       FL++D  + S D+LP++ +I+L + PR++V++NPLE
Sbjct: 598  IIGNSAFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLE 657

Query: 658  QERFSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGV 717
            Q+R S+VS+ V+SP V+V S  G+P+ VQ+SA W +A       Y++S    +P LGL V
Sbjct: 658  QDRISLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKV 717

Query: 718  LQLQLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGL 777
             ++      +  L   V +Y +     V     F ++ + +      L N ++ + F   
Sbjct: 718  YKILESASSNSHLADYV-LYKN----KVEDSGIFTIKNMINTEEGITLENSFVLLRFD-Q 771

Query: 778  TGLLKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTE 837
            TGL+K +   ++    +V++Q   YGT   +DKSGAYLFLPDG AKPYV   PP +RVT 
Sbjct: 772  TGLMKQMMTKEDGKHHEVNVQFSWYGTTIKRDKSGAYLFLPDGNAKPYVYTTPPFVRVTH 831

Query: 838  GPFFSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGI 897
            G  +SEV  +++H+   VRLY++ G+EG S+++S++VDIR   N+E+A+ I +DI SQ  
Sbjct: 832  GRIYSEVTCFFDHVTHRVRLYHIQGIEGQSVEVSNIVDIRKVYNREIAMKISSDIKSQNR 891

Query: 898  FFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLE 957
            F+TDLNG+Q+QPR  L KLPLQAN YPM  MAYIQDA+ RLTL +AQ+LGVSSL  GQ+E
Sbjct: 892  FYTDLNGYQIQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIE 951

Query: 958  VILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEVQDSHSTSYPSLLSHLTSM 1017
            VI+DRRLMQDDNRGL QG++DNK T N FR+LLE+R+  +  ++  S SYPSLLSH+TS 
Sbjct: 952  VIMDRRLMQDDNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSS 1011

Query: 1018 YLNAPALALPVARMQLPGPGLR---SFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETAL 1074
             +N P   +P+A  +   P L     F PL SSLPCD HL+NLRT+Q++     S E AL
Sbjct: 1012 LMNHP--VIPMAN-KFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAAL 1068

Query: 1075 ILHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTD 1134
            ILHRKGFDC   +K  G  C+T+QGK+ +  L +   V  L P+SL+L++      N ++
Sbjct: 1069 ILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISE 1128

Query: 1135 VYLEPMEIATFRLRL 1149
            + L PMEI+TFR++L
Sbjct: 1129 INLSPMEISTFRIQL 1143


>gi|51873064 mannosidase, alpha, class 2B, member 1 precursor [Homo
            sapiens]
          Length = 1011

 Score =  287 bits (735), Expect = 4e-77
 Identities = 289/1036 (27%), Positives = 444/1036 (42%), Gaps = 154/1036 (14%)

Query: 166  LQVFVVPHSHNDPGWIKTFDKYYT--------EQTQHILNSMVSKLQEDPRRRFLWAEVS 217
            L V ++PH+H+D GW+KT D+Y+            Q+IL+S++S L  DP RRF++ E++
Sbjct: 63   LNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVEIA 122

Query: 218  FFAKWWDNINVQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERN 277
            FF++WW       +  VR LV  G+LE A GGWVM DEA +HY A++DQ+  G ++LE  
Sbjct: 123  FFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLEDT 182

Query: 278  LG--ATPRSGWAVDPFGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQT 335
             G    PR  W +DPFG+S     L  +         R+ Y  K        +E +WR +
Sbjct: 183  FGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWRAS 242

Query: 336  WDSDSST-DIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEA 394
                  T D+F  ++P   Y+ P     D  + C           ++ P    PR+  E 
Sbjct: 243  TSLKPPTADLFTGVLP-NGYNPPRNLCWD--VLC-----------VDQPLVEDPRS-PEY 287

Query: 395  NVAERAALLLDQYRKKSQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSR-- 452
            N  E     L+    + + +R+N  ++ +G DF+Y+    W   F N  +L    N++  
Sbjct: 288  NAKELVDYFLNVATAQGRYYRTNHTVMTMGSDFQYENANMW---FKNLDKLIRLVNAQQA 344

Query: 453  PNLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRP 512
                V   + T + Y   L K            + V   DFF YAD    +WTGY++SRP
Sbjct: 345  KGSSVHVLYSTPACYLWELNKANLT--------WSVKHDDFFPYADGPHQFWTGYFSSRP 396

Query: 513  FYKSLDRVLEAHLRGAEVLYSLAAAHARRSGLAGRYPLSDFTLLTEARRTLGLFQHHDAI 572
              K  +R+    L+    L +L    A      G Y   D   L EA   + + QHHDA+
Sbjct: 397  ALKRYERLSYNFLQVCNQLEALVGLAAN----VGPYGSGDSAPLNEA---MAVLQHHDAV 449

Query: 573  TGTAKEAVVVDYGVRLLRSLVNLKQVIIHAAHYLVLGDKETYHFDPEAPFLQVDDTRLSH 632
            +GT+++ V  DY  R L +     +V++  A   + G K+ + F  +   L +    LS 
Sbjct: 450  SGTSRQHVANDY-ARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQ---LNISICPLSQ 505

Query: 633  DALPERTVIQLDSSPRF-VVLFNPLEQERFSMVSLLVNSPRVRVLSEEGQPLAVQISAHW 691
             A             RF V+++NPL ++   MV L V+     V    G+ +   +    
Sbjct: 506  TA------------ARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDPNGRTVPSDVVIFP 553

Query: 692  SSATEAVPDVYQVSVPVRLPALGLGVLQLQLGLDGHRTLPSSVRIYLHGRQLSVSRHEAF 751
            SS ++A P   ++     LPALG     +       R  P +               +  
Sbjct: 554  SSDSQAHPP--ELLFSASLPALGFSTYSV---AQVPRWKPQA------------RAPQPI 596

Query: 752  PLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSIRRVDEEHEQQVDMQVLVY----GTRTS 807
            P R   S +    + N +++  F   TGLL  I  ++++    V      Y    G   S
Sbjct: 597  PRR---SWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNES 653

Query: 808  KDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEVVAYYE-HIHQAVRLYNLPGVEGL 866
               SGAY+F P+ + KP        + + + P   EV   +     Q VRLY  PG   L
Sbjct: 654  DQASGAYIFRPN-QQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLY--PGQRHL 710

Query: 867  SLDIS-SLVDIRDYVNKELALHIHTDIDSQGIFFTDLNGFQVQPRR--------YLKKLP 917
             L+ S   + + D   KE+     T ++++G F+TD NG ++  RR          +  P
Sbjct: 711  ELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEP 770

Query: 918  LQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGLK 977
            +  N+YP+    YI D   +LT+ T ++ G SSL+DG LE+++ RRL++DD RG+ + L 
Sbjct: 771  VAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLM 830

Query: 978  DNKRTCNRFRLLLERRTVGSEVQDSH----STSYPSLLSH--LTSMYLNAPALALPV--- 1028
            +N                G+ V+  H     T+  +   H  L    + AP + L     
Sbjct: 831  ENGS--------------GAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGG 876

Query: 1029 ARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDTLPSAETALILHRKGFDCGLEAK 1088
            A   L  P    F  L   LP   HLL L +   E   L       +    G D G   +
Sbjct: 877  AAYNLGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAV----GEDSG---R 929

Query: 1089 NLGFNCTTSQGKVALGSLFHGLDVVFLQPTSL-----------------TLLYPLASP-- 1129
            NL    T +     L  LF    +  LQ T+L                 T   P  +P  
Sbjct: 930  NLSAPVTLN-----LRDLFSTFTITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQ 984

Query: 1130 SNSTDVYLEPMEIATF 1145
             +  ++ LEPMEI TF
Sbjct: 985  LDPANITLEPMEIRTF 1000


>gi|50659093 mannosidase, alpha, class 2B, member 2 [Homo sapiens]
          Length = 1009

 Score =  270 bits (690), Expect = 6e-72
 Identities = 246/851 (28%), Positives = 371/851 (43%), Gaps = 96/851 (11%)

Query: 163 AEDLQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKW 222
           A  ++ FVVPHSH D GW+ T  +       ++  S+V +L    +RRF+  E  FF  W
Sbjct: 24  AGPIRAFVVPHSHMDVGWVYTVQESMRAYAANVYTSVVEELARGQQRRFIAVEQEFFRLW 83

Query: 223 WDNI-NVQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGAT 281
           WD + + Q++  VR+L+  G+LE   GG VM DEA +H    I QL EGH +L    G  
Sbjct: 84  WDGVASDQQKYQVRQLLEEGRLEFVIGGQVMHDEAVTHLDDQILQLTEGHGFLYETFGIR 143

Query: 282 PRSGWAVDPFGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSS 341
           P+  W VDPFG S+T P L   A   + L  R+ Y +K        L+F+WR +      
Sbjct: 144 PQFSWHVDPFGASATTPTLFALAGFNAHLGSRIDYDLKAAMQEARGLQFVWRGSPSLSER 203

Query: 342 TDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRIN--CPWKVPPR---------A 390
            +IF H+M  YSY  P              F    G   N    +  PP+          
Sbjct: 204 QEIFTHIMDQYSYCTP----------SHIPFSNRSGFYWNGVAVFPKPPQDGVYPNMSEP 253

Query: 391 ITEANVAERAALLLDQYRKKSQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFN 450
           +T AN+   A  L+   ++++  FR+  +L P G D ++        QF N   L D  N
Sbjct: 254 VTPANINLYAEALVANVKQRAAWFRTPHVLWPWGCDKQFFNA---SVQFANMDPLLDHIN 310

Query: 451 SR-PNLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYT 509
           S    L V  Q+ TL DYF AL+    V    R         DF  Y+      WTG+YT
Sbjct: 311 SHAAELGVSVQYATLGDYFRALH-ALNVTWRVRD------HHDFLPYSTEPFQAWTGFYT 363

Query: 510 SRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRSGLAGRYPLSDFTLLTEARRTLGLFQHH 569
           SR   K L R   A L   E +++     A R  L   + L     L + R  +   QHH
Sbjct: 364 SRSSLKGLARRASALLYAGESMFTRYLWPAPRGHLDPTWALQQ---LQQLRWAVSEVQHH 420

Query: 570 DAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHAAHYLVLGDKETYHFDPEAPFLQVDDTR 629
           DAITGT    V   Y   L   ++ +++++      +VL +       P+AP        
Sbjct: 421 DAITGTESPKVRDMYATHLASGMLGMRKLMAS----IVLDE-----LQPQAPM------A 465

Query: 630 LSHDALPERTVIQLDSSPRFVVLFNPLEQERFSMVSLLVNSPRVRVLSEEGQPLAVQISA 689
            S DA P         +  F  ++NPL     ++V+L V  P VRV  E G P+  QI  
Sbjct: 466 ASSDAGP---------AGHFASVYNPLAWTVTTIVTLTVGFPGVRVTDEAGHPVPSQI-- 514

Query: 690 HWSSATEAVPDVYQVSVPVRLPALG---LGVLQLQLGLDGHRTLPSSVRIYLH-GRQLSV 745
              ++TE  P  Y + +   +P L      +       +G +   ++V   L  GR+L  
Sbjct: 515 --QNSTE-TPSAYDLLILTTIPGLSYRHYNIRPTAGAQEGTQEPAATVASTLQFGRRLR- 570

Query: 746 SRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSIRRVDEEHEQQVDMQVLVY--- 802
                   R   +G     ++N    V     T L+ SI         +V  + L Y   
Sbjct: 571 -------RRTSHAGRYLVPVANDCYIVLLDQDTNLMHSIWERQSNRTVRVTQEFLEYHVN 623

Query: 803 GTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEVVAYY------EHIHQAVR 856
           G       S  YLF P   A P    E   + +  G   +E+  Y+      ++   A+R
Sbjct: 624 GDVKQGPISDNYLFTPGKAAVP--AWEAVEMEIVAGQLVTEIRQYFYRNMTAQNYTYAIR 681

Query: 857 LYNLPGVEGLSLDISSLVDIRDY------VNKELALHIHTDIDSQGIFFTDLNGFQVQPR 910
                  +G   ++      ++Y      +N+E  L   T+++SQ + ++D NG+Q+Q R
Sbjct: 682 SRLTHVPQGHDGELLCHRIEQEYQAGPLELNREAVLRTSTNLNSQQVIYSDNNGYQMQRR 741

Query: 911 RYLKKL--PLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDD 968
            Y+  +   +  N+YPM   A+++D + RL L + +A G+SS  +GQ+EV+L RRL  + 
Sbjct: 742 PYVSYVNNSIARNYYPMVQSAFMEDGKSRLVLLSERAHGISSQGNGQVEVMLHRRLWNNF 801

Query: 969 NRGLGQGLKDN 979
           +  LG  L  N
Sbjct: 802 DWDLGYNLTLN 812


>gi|46852164 mannosidase, alpha, class 2C, member 1 [Homo sapiens]
          Length = 1040

 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 41/184 (22%), Positives = 70/184 (38%), Gaps = 13/184 (7%)

Query: 173 HSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRR-RFLWA-EVSFFAKWWDNINVQK 230
           H H D  W+  F     E  +    S V+ LQ   R   F++A   +   +W  +     
Sbjct: 258 HCHIDTAWLWPFK----ETVRKCARSWVTALQLMERNPEFIFACSQAQQLEWVKSRYPGL 313

Query: 231 RAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDP 290
            + ++     GQ     G WV  D       A++ Q ++G  +  +  G      W  D 
Sbjct: 314 YSRIQEFACRGQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDT 373

Query: 291 FGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMP 350
           FGYS+ +P ++    +   L Q++ + +   F   H   F     W+    + +  H  P
Sbjct: 374 FGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSF--PHHTFF-----WEGLDGSRVLVHFPP 426

Query: 351 FYSY 354
             SY
Sbjct: 427 GDSY 430


>gi|116812628 coiled-coil domain containing 67 [Homo sapiens]
          Length = 604

 Score = 32.7 bits (73), Expect = 2.0
 Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 11/131 (8%)

Query: 877  RDYVNKELALHIHT-DIDSQGIFFTD-LNGFQVQPRRYL-----KKLPLQANFYPMPVMA 929
            R++  +E+    H   +D+Q    ++  N FQ Q + Y      KK  L+ +   +P + 
Sbjct: 151  REWDKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGKKQCLEDSSSEIPRL- 209

Query: 930  YIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNRFRLL 989
             I D      ++      +  LK    E+ L R  +QD+N+ L Q LK  +R C      
Sbjct: 210  -ICDPDPNCEINERDEFIIEKLKSAVNEIALSRNKLQDENQKLLQELKMYQRQCQAMEAG 268

Query: 990  LERRTVGSEVQ 1000
            L    V SE+Q
Sbjct: 269  LSE--VKSELQ 277


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,841,678
Number of Sequences: 37866
Number of extensions: 2154040
Number of successful extensions: 4931
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 4900
Number of HSP's gapped (non-prelim): 10
length of query: 1150
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1037
effective length of database: 13,968,660
effective search space: 14485500420
effective search space used: 14485500420
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.