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Search of human proteins with 50557644
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50557644 zinc finger, FYVE domain containing 27 isoform b
[Homo sapiens]
(411 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Ho... 837 0.0
gi|50557646 zinc finger, FYVE domain containing 27 isoform a [Ho... 830 0.0
gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Ho... 816 0.0
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 58 2e-08
gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens] 52 7e-07
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 52 7e-07
gi|217272865 myotubularin related protein 4 [Homo sapiens] 52 1e-06
gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens] 50 3e-06
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 50 4e-06
gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens] 49 6e-06
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 49 1e-05
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 48 2e-05
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 48 2e-05
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 47 3e-05
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom... 47 3e-05
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo... 47 3e-05
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 45 2e-04
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 45 2e-04
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 45 2e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 45 2e-04
gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens] 45 2e-04
gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens] 45 2e-04
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 41 0.002
gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform... 40 0.003
gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Hom... 38 0.015
gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Hom... 38 0.015
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 37 0.043
gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens] 37 0.043
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su... 36 0.056
gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens] 36 0.073
>gi|50557644 zinc finger, FYVE domain containing 27 isoform b [Homo
sapiens]
Length = 411
Score = 837 bits (2161), Expect = 0.0
Identities = 411/411 (100%), Positives = 411/411 (100%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLE 300
HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLE
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLE 300
Query: 301 DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL 360
DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL
Sbjct: 301 DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL 360
Query: 361 KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 411
KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 361 KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 411
>gi|50557646 zinc finger, FYVE domain containing 27 isoform a [Homo
sapiens]
Length = 416
Score = 830 bits (2145), Expect = 0.0
Identities = 411/416 (98%), Positives = 411/416 (98%), Gaps = 5/416 (1%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTE-----DLTPGSVEEAEEAEPDEEFKDAIEETH 295
HAFESPPPPDVGGKDGLMDSTPALTPTE DLTPGSVEEAEEAEPDEEFKDAIEETH
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTESLSSQDLTPGSVEEAEEAEPDEEFKDAIEETH 300
Query: 296 LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 355
LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA
Sbjct: 301 LVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSA 360
Query: 356 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 411
TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 361 TFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 416
>gi|50557648 zinc finger, FYVE domain containing 27 isoform c [Homo
sapiens]
Length = 404
Score = 816 bits (2109), Expect = 0.0
Identities = 404/411 (98%), Positives = 404/411 (98%), Gaps = 7/411 (1%)
Query: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG
Sbjct: 1 MQTSEREGSGPELSPSVMPEAPLESPPFPTKSPAFDLFNLVLSYKRLEIYLEPLKDAGDG 60
Query: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS
Sbjct: 61 VRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAWYSVGALMISVPALLGYLQEVCRARLPDS 120
Query: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV
Sbjct: 121 ELMRRKYHSVRQEDLQRGRLSRPEAVAEVKSFLIQLEAFLSRLCCTCEAAYRVLHWENPV 180
Query: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE
Sbjct: 181 VSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNVEFFRVVSEYRASLQQRMNPKQEE 240
Query: 241 HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLE 300
HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIE E
Sbjct: 241 HAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGSVEEAEEAEPDEEFKDAIE-------E 293
Query: 301 DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL 360
DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL
Sbjct: 294 DDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVL 353
Query: 361 KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 411
KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK
Sbjct: 354 KKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTLSK 404
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 57.8 bits (138), Expect = 2e-08
Identities = 39/149 (26%), Positives = 62/149 (41%), Gaps = 32/149 (21%)
Query: 281 AEPDEEFKDAIEETHLVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRK 340
+ PD+ + +++ + V D + L ++G + E L+ +V L RL
Sbjct: 1005 SSPDQPSRSHLDDDGMSVYTDT------IQQRLRQIESGHQQEVETLKKQVQELKSRLES 1058
Query: 341 RYPTNN------FGN--------------CTGCSATFSVLKKRRSCSNCGNSFCSRCCSF 380
+Y T++ FG+ C C + F + ++ C NCGN FCS CC+
Sbjct: 1059 QYLTSSLHFNGDFGDEVMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQ 1118
Query: 381 KVPKSSMGATAPEAQRETVFVCASCNQTL 409
KVP S P VC SC +L
Sbjct: 1119 KVPVPSQQLFEPSR------VCKSCYSSL 1141
>gi|55741864 zinc finger, FYVE domain containing 28 [Homo sapiens]
Length = 887
Score = 52.4 bits (124), Expect = 7e-07
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 6/63 (9%)
Query: 343 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 402
P G CT C A F+V++++ C +CG FCSRC S P G P V VC
Sbjct: 816 PDEACGFCTACKAPFTVIRRKHHCRSCGKIFCSRCSSHSAPLPRYGQVKP------VRVC 869
Query: 403 ASC 405
C
Sbjct: 870 THC 872
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 52.4 bits (124), Expect = 7e-07
Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 324 NEVLRSKVSRLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVP 383
+E +V + + + P + +C C + F + ++ C NCGN FCS CC+ KVP
Sbjct: 1099 SEASWEQVDKQDTEMTRWLPDHLAAHCYACDSAFWLASRKHHCRNCGNVFCSSCCNQKVP 1158
Query: 384 KSSMGATAPEAQRETVFVCASCNQTL 409
S P VC SC +L
Sbjct: 1159 VPSQQLFEPSR------VCKSCYSSL 1178
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 51.6 bits (122), Expect = 1e-06
Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 17/129 (13%)
Query: 278 AEEAEPDEEFKDAIEETHLVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTER 337
A AEP +++D L++ +G+ ED + LS E V +
Sbjct: 1057 APPAEPPMDYED-----DFTCLKESDGSD--TEDFGSDHSEDCLS--EASWEPVDKKETE 1107
Query: 338 LRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQ-R 396
+ + P + +C C F + K+R C NCGN FC+ CC K+P P+ Q
Sbjct: 1108 VTRWVPDHMASHCYNCDCEFWLAKRRHHCRNCGNVFCAGCCHLKLP-------IPDQQLY 1160
Query: 397 ETVFVCASC 405
+ V VC SC
Sbjct: 1161 DPVLVCNSC 1169
>gi|116268103 zinc finger, FYVE domain containing 19 [Homo sapiens]
Length = 471
Score = 50.4 bits (119), Expect = 3e-06
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 7/62 (11%)
Query: 350 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 409
C GC+ F++ KK C NCG +FCS C SF A P VC C++ L
Sbjct: 80 CYGCAVKFTLFKKEYGCKNCGRAFCSGCLSF-------SAAVPRTGNTQQKVCKQCHEVL 132
Query: 410 SK 411
++
Sbjct: 133 TR 134
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 50.1 bits (118), Expect = 4e-06
Identities = 39/158 (24%), Positives = 62/158 (39%), Gaps = 41/158 (25%)
Query: 281 AEPDEEFKDAIEETHLVVLEDDEGAPCPAEDELALQDNGFLSKNEVLRSKVSRLTERLRK 340
+ PD+ + +++ + V D + L ++G + E L+ +V L RL
Sbjct: 1005 SSPDQPSRSHLDDDGMSVYTDT------IQQRLRQIESGHQQEVETLKKQVQELKSRLES 1058
Query: 341 RYPTNN------FGN--------------CTGCSATFSVLKKRRSCS---------NCGN 371
+Y T++ FG+ C C + F + ++ C NCGN
Sbjct: 1059 QYLTSSLHFNGDFGDEVMTRWLPDHLAAHCYACDSAFWLASRKHHCRDTDRVDQTWNCGN 1118
Query: 372 SFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 409
FCS CC+ KVP S P VC SC +L
Sbjct: 1119 VFCSSCCNQKVPVPSQQLFEPSR------VCKSCYSSL 1150
>gi|13129054 zinc finger, FYVE domain containing 21 [Homo sapiens]
Length = 234
Score = 49.3 bits (116), Expect = 6e-06
Identities = 24/63 (38%), Positives = 26/63 (41%), Gaps = 6/63 (9%)
Query: 343 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 402
P C C A F L ++ C CG FC RCCS KVP M P Q C
Sbjct: 43 PDKECRRCMQCDAKFDFLTRKHHCRRCGKCFCDRCCSQKVPLRRMCFVDPVRQ------C 96
Query: 403 ASC 405
A C
Sbjct: 97 AEC 99
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 48.5 bits (114), Expect = 1e-05
Identities = 19/48 (39%), Positives = 26/48 (54%)
Query: 343 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGAT 390
P + C CS F+ ++R C CG FCSRCC+ ++P MG T
Sbjct: 157 PDSQCKECYDCSEKFTTFRRRHHCRLCGQIFCSRCCNQEIPGKFMGYT 204
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 6/61 (9%)
Query: 349 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 408
+C+GCS FS+ ++R C NCG FC +C F+ + ++P V VC +C
Sbjct: 214 SCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSP------VRVCQNCYYN 267
Query: 409 L 409
L
Sbjct: 268 L 268
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 47.8 bits (112), Expect = 2e-05
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 6/61 (9%)
Query: 349 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 408
+C+GCS FS+ ++R C NCG FC +C F+ + ++P V VC +C
Sbjct: 3459 SCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSP------VRVCQNCYYN 3512
Query: 409 L 409
L
Sbjct: 3513 L 3513
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 343 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 402
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 403 ASCNQTL 409
C+ L
Sbjct: 751 VICHSVL 757
>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
sapiens]
Length = 1425
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 343 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 402
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 403 ASCNQTL 409
C+ L
Sbjct: 751 VICHSVL 757
>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
sapiens]
Length = 762
Score = 47.0 bits (110), Expect = 3e-05
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 343 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 402
P + NC C A F+ K+R C CG FC+ CCS K M R+ VC
Sbjct: 698 PDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYM-------DRKEARVC 750
Query: 403 ASCNQTL 409
C+ L
Sbjct: 751 VICHSVL 757
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 11/103 (10%)
Query: 310 EDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFGNCTGCSATFSVLKKRRSC 366
E E ALQ+ G LS++++ + + + L+ + +C C FS+ +++ C
Sbjct: 497 EQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHC 556
Query: 367 SNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 409
NCG+ FC+ C S ++ A + + V VC SC+ L
Sbjct: 557 RNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTLL 591
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 11/103 (10%)
Query: 310 EDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFGNCTGCSATFSVLKKRRSC 366
E E ALQ+ G LS++++ + + + L+ + +C C FS+ +++ C
Sbjct: 497 EQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHC 556
Query: 367 SNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 409
NCG+ FC+ C S ++ A + + V VC SC+ L
Sbjct: 557 RNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTLL 591
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/103 (27%), Positives = 50/103 (48%), Gaps = 11/103 (10%)
Query: 310 EDELALQDNGF-LSKNEVLRSKVSRLTERLRKR--YPTNNFGNCTGCSATFSVLKKRRSC 366
E E ALQ+ G LS++++ + + + L+ + +C C FS+ +++ C
Sbjct: 605 EQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHC 664
Query: 367 SNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQTL 409
NCG+ FC+ C S ++ A + + V VC SC+ L
Sbjct: 665 RNCGHIFCNTCSSNEL--------ALPSYPKPVRVCDSCHTLL 699
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 44.7 bits (104), Expect = 2e-04
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 8/67 (11%)
Query: 339 RKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRET 398
RK N NC C FSV +R C CGN FC+ C S+ A P + ++
Sbjct: 1347 RKWAEDNEVQNCMACGKGFSVTVRRHHCRQCGNIFCAEC-------SAKNALTP-SSKKP 1398
Query: 399 VFVCASC 405
V VC +C
Sbjct: 1399 VRVCDAC 1405
>gi|157426866 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 343 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 402
P + NC C F+ K+R C CG FC CC+ K + A VC
Sbjct: 746 PDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEAR--------VC 797
Query: 403 ASCNQTLSK 411
C +T+SK
Sbjct: 798 VVCYETISK 806
>gi|157426864 zinc finger, FYVE domain containing 16 [Homo sapiens]
Length = 1539
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 8/69 (11%)
Query: 343 PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVC 402
P + NC C F+ K+R C CG FC CC+ K + A VC
Sbjct: 746 PDSEAPNCMNCQVKFTFTKRRHHCRACGKVFCGVCCNRKCKLQYLEKEAR--------VC 797
Query: 403 ASCNQTLSK 411
C +T+SK
Sbjct: 798 VVCYETISK 806
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 40.8 bits (94), Expect = 0.002
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 8/61 (13%)
Query: 349 NCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQT 408
+C C FS+ K++ C NCG FC+ C ++P S +P+ R VC SC+
Sbjct: 580 HCKLCEKEFSLSKRKHHCRNCGEIFCNACSDNELPLPS----SPKPVR----VCDSCHAL 631
Query: 409 L 409
L
Sbjct: 632 L 632
>gi|110815813 ankyrin repeat and FYVE domain containing 1 isoform 1
[Homo sapiens]
Length = 1170
Score = 40.4 bits (93), Expect = 0.003
Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 6/78 (7%)
Query: 333 RLTERLRKRYPTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAP 392
RL + L K P + C C+A F V ++ C +CG C +C + ++P P
Sbjct: 1094 RLLDMLSKEPPWCDGSYCYECTARFGVTTRKHHCRHCGRLLCHKCSTKEIPIIKFDLNKP 1153
Query: 393 EAQRETVFVCASCNQTLS 410
V VC C L+
Sbjct: 1154 ------VRVCNICFDVLT 1165
>gi|30795182 zinc finger, FYVE domain containing 1 isoform 2 [Homo
sapiens]
Length = 362
Score = 38.1 bits (87), Expect = 0.015
Identities = 36/158 (22%), Positives = 54/158 (34%), Gaps = 15/158 (9%)
Query: 255 DGLMDSTPALT---PTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLEDDEGAPCPAED 311
+G DS + T P P V + + A+ E + DDEG A
Sbjct: 210 EGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQV----DDEGGTLIARK 265
Query: 312 ELALQDNGFLSKNEVLRSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNC 369
N + + + + + R Y P + +C C FS+ + C C
Sbjct: 266 VGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRAC 325
Query: 370 GNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQ 407
G FC C + S G P V VC +CN+
Sbjct: 326 GQGFCDECSHDRRAVPSRGWDHP------VRVCFNCNK 357
Score = 35.8 bits (81), Expect = 0.073
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 328 RSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKS 385
++ S LT+++ Y P + +C C+ +F + C CG FC C S P
Sbjct: 165 KAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVP 224
Query: 386 SMG-ATAPEAQRETVFVCASC 405
G AP V VC +C
Sbjct: 225 ERGWGPAP------VRVCDNC 239
>gi|30795180 zinc finger, FYVE domain containing 1 isoform 1 [Homo
sapiens]
Length = 777
Score = 38.1 bits (87), Expect = 0.015
Identities = 36/158 (22%), Positives = 54/158 (34%), Gaps = 15/158 (9%)
Query: 255 DGLMDSTPALT---PTEDLTPGSVEEAEEAEPDEEFKDAIEETHLVVLEDDEGAPCPAED 311
+G DS + T P P V + + A+ E + DDEG A
Sbjct: 625 EGFCDSCSSKTRPVPERGWGPAPVRVCDNCYEARNVQLAVTEAQV----DDEGGTLIARK 680
Query: 312 ELALQDNGFLSKNEVLRSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNC 369
N + + + + + R Y P + +C C FS+ + C C
Sbjct: 681 VGEAVQNTLGAVVTAIDIPLGLVKDAARPAYWVPDHEILHCHNCRKEFSIKLSKHHCRAC 740
Query: 370 GNSFCSRCCSFKVPKSSMGATAPEAQRETVFVCASCNQ 407
G FC C + S G P V VC +CN+
Sbjct: 741 GQGFCDECSHDRRAVPSRGWDHP------VRVCFNCNK 772
Score = 35.8 bits (81), Expect = 0.073
Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 9/81 (11%)
Query: 328 RSKVSRLTERLRKRY--PTNNFGNCTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKS 385
++ S LT+++ Y P + +C C+ +F + C CG FC C S P
Sbjct: 580 KAVTSWLTDQIAPAYWRPNSQILSCNKCATSFKDNDTKHHCRACGEGFCDSCSSKTRPVP 639
Query: 386 SMG-ATAPEAQRETVFVCASC 405
G AP V VC +C
Sbjct: 640 ERGWGPAP------VRVCDNC 654
>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.043
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 349 NCTGCSATF-SVLKKRRSCSNCGNSFCSRCCSFKVPKS 385
+C C TF S+ K+R C CG C +C FK S
Sbjct: 537 SCKSCGETFNSITKRRHHCKLCGAVICGKCSEFKAENS 574
>gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
Length = 725
Score = 36.6 bits (83), Expect = 0.043
Identities = 15/38 (39%), Positives = 19/38 (50%), Gaps = 1/38 (2%)
Query: 349 NCTGCSATF-SVLKKRRSCSNCGNSFCSRCCSFKVPKS 385
+C C TF S+ K+R C CG C +C FK S
Sbjct: 537 SCKSCGETFNSITKRRHHCKLCGAVICGKCSEFKAENS 574
>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
substrate [Homo sapiens]
Length = 777
Score = 36.2 bits (82), Expect = 0.056
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 350 CTGCSATFSVLKKRRSCSNCGNSFCSRCCSFKVPKSSMGATAPE-AQRETVFVCASCNQT 408
C C F V+ ++ C CG FC +C SS +T P+ + V VC C +
Sbjct: 166 CHRCRVQFGVMTRKHHCRACGQIFCGKC-------SSKYSTIPKFGIEKEVRVCEPCYEQ 218
Query: 409 LSK 411
L++
Sbjct: 219 LNR 221
>gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens]
Length = 497
Score = 35.8 bits (81), Expect = 0.073
Identities = 56/242 (23%), Positives = 97/242 (40%), Gaps = 32/242 (13%)
Query: 52 EPLKDAGDGVRYLLRWQMPLCSLLTCLGLNVLFLTLNEGAW--YSVGALMISVPALLGYL 109
EP+ G LL W+ PL SLL + N+LF L W Y + ++MI ++ +
Sbjct: 74 EPVLWLGCRADELLSWKRPLRSLLGFVAANLLFWFLALTPWRVYHLISVMILGRVIMQII 133
Query: 110 QEVCRARLPDSELMR---RKYHSVRQEDLQRGRLSR--PEAVAEVKSFLIQLEAFLSR-- 162
+++ +R ++L R + + + +R RLS E+ FL ++ F +
Sbjct: 134 KDMVLSRTRGAQLWRSLSESWEVINSKPDERPRLSHCIAESWMNFSIFLQEMSLFKQQSP 193
Query: 163 -----LCCTCEAAYRVLHWENPVVSSQFYGALLGTVCMLYLLPLCWVLTLLNSTLFLGNV 217
L C+ + +L G+ + V + YLL LC L L +G
Sbjct: 194 GKFCLLVCSVCTFFTIL------------GSYIPGVILSYLLLLCAFLCPLFKCNDIGQK 241
Query: 218 EFFRVVS---EYRASLQQRMNPKQEEHAFESPPPPDVGGKDGLMDSTPALTPTEDLTPGS 274
+ ++ S + + + +N K+ E S + KD AL P LT +
Sbjct: 242 IYSKIKSVLLKLDFGIGEYINQKKRE---RSEADKEKSHKDDSELDFSALCPKISLTVAA 298
Query: 275 VE 276
E
Sbjct: 299 KE 300
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,883,235
Number of Sequences: 37866
Number of extensions: 899927
Number of successful extensions: 4980
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 4864
Number of HSP's gapped (non-prelim): 155
length of query: 411
length of database: 18,247,518
effective HSP length: 105
effective length of query: 306
effective length of database: 14,271,588
effective search space: 4367105928
effective search space used: 4367105928
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.